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Dosage Sensitivity And The Evolution Of Dosage Compensation: Tests Of The Insensitive Sex Chromosome Hypothesis In Flour Beetles, Shana Pau

Biology Dissertations

Sex chromosome evolution generates imbalances in gene dosage that can disrupt gene expression and organismal function. These imbalances are often resolved through dosage compensation mechanisms, yet the factors that drive the emergence and diversity of these systems remain poorly understood. This dissertation addresses a central question in evolutionary genomics: what governs the evolution of dosage compensation?

Focusing on dosage sensitivity as a potential driver, I evaluate the Insensitive Sex Chromosome Hypothesis (ISCH), which predicts that chromosome-wide compensation is more likely to evolve in genomic contexts that are not depleted of dosage-sensitive genes. Using flour beetles (Tribolium spp.) as a …

Coordinating The Layers: Regulation Of Peptidoglycan Synthesis And Cell Wall Assembly In Mycobacterium Smegmatis By Murj And Pgfa, Karen Emmanuella Samaga-De-Tembiwa

Biology Dissertations

The mycobacterial cell envelope consists of three covalently linked layers whose synthesis must be coordinated to maintain structural integrity during polar growth. While the biosynthetic enzymes for each layer are well characterized, the molecular mechanisms that coordinate synthesis across layers have remained poorly understood. This thesis investigates two essential transmembrane proteins, PgfA and MurJ, that regulate peptidoglycan metabolism in Mycobacterium smegmatis and provide new insight into how mycobacteria synchronize cell wall assembly.

We present evidence that PgfA functions as a bifunctional regulator that links peptidoglycan metabolism to the availability of trehalose monomycolate (TMM), a key mycolic acid precursor. Through epistasis …

Application Of Matlab Simulation For Quantum Wells And Absorption Modelling, Mohamed Nur

Electrical Engineering Theses

The Quantum-Well User Entered Simulation Tool (QUEST), originally developed at the University of Texas at Arlington in 2005, is a simulation program built in MATLAB for computing energy eigenvalues and wavefunctions in user-defined semiconductor quantum well structures. This thesis presents a new revision and extension of QUEST with three primary contributions: compatibility updates to the existing MATLAB codebase, intersubband absorption modelling, and a redesigned graphical user interface for ease-of-use in testing.

The modernization effort for this program addresses incompatibilities introduced by changes to the MATLAB runtime environment since QUEST’s original release in 2005, including corrections to the self-consistent Schrödinger-Poisson solver …

A Bayesian Late-Fusion Supportability Framework For Rare-Disease Severity Prediction In Glut1 Deficiency Syndrome, Jordan M. Rodriguez

Mathematics Dissertations

Glucose transporter type 1 deficiency syndrome (GLUT1-DS) is a rare neurometabolic disorder with heterogeneous neurological and developmental severity. Because patient-level severity is not observed as a single validated outcome, this dissertation develops a Bayesian late-fusion supportability framework for constructing and predicting an ordered latent severity phenotype from clinical, genetic, and EEG-derived evidence. The primary target was constructed in a larger clinical cohort using age-5 symptom burden and learning cognition, then assigned to an aligned multimodal prediction cohort. Target-defining variables were excluded from supervised predictors, and models were evaluated using patient-exclusive cross-validation with training-fold preprocessing and fold-wise EEG PCA.

The primary …

Improving Blood Pressure Control Through Lifestyle Modification In African Americans Adults With Uncontrolled Hypertension, Tasha Leonard

Doctor of Nursing Practice (DNP) Scholarly Projects

African American adults have the highest incidence of uncontrolled hypertension (HTN), leading to premature cardiovascular death in Texas and worldwide. In a South Texas cardiac clinic, over 90% of African American adults with HTN also have obesity, compared with 55% of their Caucasian counterparts. The most prevalent factor affecting this group is poor understanding of blood pressure management, which leads to nonadherence to dietary and exercise recommendations, medication regimens, and blood pressure monitoring. The objective was to determine whether lifestyle modification using a hypertensive bundle would improve blood pressure management among African American adults in the clinical setting. The initiative …

A Guideline To Address Barriers To Mental Health Treatment Experienced By Law Enforcement Officers, Jacqueline Estrella

Doctor of Nursing Practice (DNP) Scholarly Projects

Problem: Law enforcement officers are exposed to repeated trauma on the job that may negatively affect their mental health. Officers may avoid seeking mental health treatment due to police culture, stigma, and other barriers which may increase risks for suicide, absenteeism, and maladaptive coping.

Objectives: Develop an evidenced-based guideline to address barriers law enforcement officers face in seeking mental health treatment.

Methods: The National Quality Measures Clearinghouse (NQMC) Domain Framework was used to guide a literature review to identify best practices suitable for a guideline. Articles were graded for strength based on the John Hopkins Nursing Evidence Based Practice (JHNEBP) …

Strain-Induced Nonvolatile Domain Switching And Tunable Elastic Modulus In Ba1-Xsrxtio3 Membrane By Phase-Field Simulation., Laveeza Ahmad

Material Science and Engineering Dissertations

Ferroelectrics underpin a broad spectrum of technological applications due to its switchable ferroelectric polarization and the associated electro-mechanical responses under electrical, optical, thermal, and mechanical stimuli. Recent advancement in membrane technology offers new opportunities to tune ferroelectric polarizations via mechanical strains at relatively large magnitude and scale. However, its influence on the tunability of mechanical responses of the membrane remains underexplored. Herein, we developed a phase-field model for free-standing Ba_1-xSr_xTiO₃ ferroelectric membranes with stress-free boundary conditions on top/bottom surfaces and achieved strain-induced nonvolatile ferroelectric domain switching in the membrane. It is discovered that a …

Anaerobic Digestion Of Food Waste Components: Modeling Biogas Production, Opeyemi E. Adelegan

Civil Engineering Dissertations

Food waste constitutes the single largest component of municipal solid waste landfilled in the United States — approximately 22% of 292.4 million tons generated in 2018 — and its anaerobic decomposition releases methane, a greenhouse gas with global warming potential approximately 27–30 times that of carbon dioxide over a 100-year horizon (IPCC, 2021). Anaerobic digestion (AD) offers an alternative management pathway that recovers energy and produces nutrient-rich digestate, but AD performance varies by as much as five-fold across food waste streams (130–630 m³ CH₄ per Mg VS added), and existing predictive tools either treat food waste as a …

Impact Of Family And Social Determinants Of Health On Behavioral And Bmi Outcomes In Adolescents With And Without Intellectual And Developmental Disabilities: An Ecological System Perspective, Pingnan Li

Social Work Theses

Adolescence is a critical developmental period during which behavioral and physical health outcomes are shaped by social and family determinants of health; yet limited research has examined how these determinants operate among adolescents with intellectual and developmental disabilities (IDD) within a multilevel ecological framework. To address this gap, this thesis used data from Years 9 and 15 of the Future of Families and Child Wellbeing Study (FFCWS), with a final analytic sample of 3,176 adolescents at Year 15, including 150 with IDD. Descriptive analyses first examined the differences in demographic characteristics, behavioral outcomes (externalizing and internalizing behaviors), and physical outcomes …

Exploring The Academic Trajectories Of Transfer Students Enrolled In An Introduction To Proof Course And Their Self-Efficacy For Proving, Sundas Hussain

Mathematics Dissertations

Transfer students entering proof-based mathematics courses face a double transition: they are adjusting to a new institution while simultaneously learning to construct mathematical proofs. Although transfer students have been widely studied in higher education and self-efficacy for proving has received increasing attention in mathematics education, little research has examined the intersection of these two areas. The purpose of this study was to better understand how transfer students’ academic trajectories shape their self-efficacy for proving. This multiple case study examined twelve transfer students enrolled in an Introduction to Proofs (ITP) course, using Bandura's (1997) four sources of self-efficacy as the …

Clinical Challenges Associated With Enhancing Hypertension Among The Underserved African American Population, Ashley Richardson

Doctor of Nursing Practice (DNP) Scholarly Projects

Background 

African Americans face a significantly higher prevalence of hypertension, tend to develop complications at younger ages, and have disproportionately higher mortality rates. Key social determinants of health (SDoH)—including food deserts, unequal access to healthcare, and geographic disparities in healthcare resources—contribute to these ongoing inequities. Addressing both systemic and individual barriers is crucial for effective hypertension management.

Objective

This study aims to assess the effectiveness of a culturally relevant, community-based intervention designed to reduce both systolic and diastolic blood pressure among Black adults with uncontrolled hypertension.

Methods 

Quality improvement (QI) initiatives typically employ multicomponent, equity-focused models. The primary components of …

Data Repository For: Dorsey Et Al., 'Rapid Transient Uplift Driven By Active Slab Tear, Southern Calabria, Italy', Rebecca J. Dorsey, Nathan D. Brown, Sergio G. Longhitano, Marco Meschis, Domenico Chiarella, Charles P. Ogle

Earth & Environmental Sciences Datasets

Southern Italy preserves a well-studied record of deformation and uplift related to migrating oblique collision, trench retreat, and tearing of subducted ocean slabs. However, the surface expression of these processes is incompletely understood due to a lack of reliable ages for marine terraces >200 m above sea level (masl). Here we use luminescence methods to date shallow marine sands from terraces ~ 100 to 1,000 masl in southern Calabria and interpolate the results with regional surface mapping. Burial ages overlap across the full range of sampled elevations with a weighted mean of 118.8 ± 8.7 thousand years before present (ka). …

The Feminine Way Of Campaigning: How Female Politicians Navigate Gender Bias, Jordan V. Pruitt

2025 Fall Honors Capstones Projects - Archive

Women are rapidly taking over the world of politics, holding more elected positions than ever before. With the increase of women in politics, we begin to question how gender stereotypes and bias affect female politicians. There are numerous studies examining the public's perception of female candidates and how they are framed differently from their male opponents in the media; however, the main objective of this project is to learn how gender affects women’s campaign strategies or public personas, and how this differs from their male counterparts. Through interviews with women in locally elected positions, this study examines these issues through …

Virtual Process Modeling Of Metal Additive Manufacturing Basedon Direct Energy Deposition In-Situ Failure, Jachin J. Ramirez

2025 Fall Honors Capstones Projects - Archive

This study builds a mesoscale finite element simulation to examine how internal stresses form during additive metal manufacturing using directed energy deposition. The goal is to track how heat and stress develop layer by layer and determine where a failure criterion could appear during the print. The model uses temperature-dependent material properties for Inconel 718 and a moving heat source defined with custom G-code.

Thermal results are mapped into a mechanical simulation to watch stress accumulate as new layers are added. Different scan paths were tested to determine whether varying heat exposure could reduce the extent of a region exceeding …

Lost In Translation: How Health Literacy Impacts Pharmaceutical Transactions From Healthcare Professionals To Patients, Grace Nwaege

2025 Fall Honors Capstones Projects - Archive

Health literacy is a core element of public health, involving the ability to access, understand, evaluate, and use information to maintain well-being. In the United States, it aligns with an average reading level of about an eighth grader, which continues to decline over time. As pharmacists serve as the final point of contact in most outpatient settings, their ability to communicate effectively at this literacy level is crucial. This study examines how pharmacies address this challenge using qualitative methods, including health literacy assessments of patient consent forms and stakeholder interviews with pharmacy technicians about resource use. Findings show materials higher …

Function Of Drosophila Melanogaster Domesticated Transposable Element Protein Dplg3 In Oogenesis And Total Fitness, Aron Herrera

2025 Fall Honors Capstones Projects - Archive

Transposable elements (TEs) are selfish DNA segments capable of self-replication and reinsertion within genomes, often harming hosts. Rarely, host genomes can adopt TEs and use their proteins for new cellular functions through molecular domestication. One example primarily expressed in Drosophila melanogaster ovaries is DPLG3. Previous Betrán Lab students generated DPLG3 loss-of-function flies and found that their ovaries misregulated one primordial and 14 testis-specific genes, leading to variable ovarian malformations. However, it is unclear when during oogenesis these misexpressions occur. We will extract RNA from non-rudimentary ovaries at early and late stages to generate cDNA for qRT-PCR analysis of three …

Power Solutions For Large Loads: Mastering Electrical Supply For New Industrial Facilities, Chris Boyer, William Bourgeois, Skyler Bryant

Mavs Open Press Open Educational Resources - Archive

The next 25 years will see unprecedented growth in U.S. electricity demand, driven primarily by data centers for AI and industrial electrification. This surge presents unique challenges for power generation, especially for large loads requiring hundreds of megawatts to gigawatts from a single location. Conventional grid expansion is inadequate, prompting the need for innovative, flexible, and sustainable solutions. This book explores the opportunities, challenges, and hybrid generation strategies to support the evolving landscape of large-scale electric loads.

Article Draft, Bob Schieffer

Bob Schieffer Vietnam War Collection

Article draft by Bob Schieffer about Master Sergeant Rodolfo Salinas in Vietnam.

Article Draft, Bob Schieffer

Bob Schieffer Vietnam War Collection

Article draft by Bob Schieffer about Major Bruce Miller in Vietnam.

Article Draft, Bob Schieffer

Bob Schieffer Vietnam War Collection

Bob Schieffer's notes of events that occured during a battle in Vietnam.

Article Draft, Bob Schieffer

Bob Schieffer Vietnam War Collection

Article draft by Bob Schieffer about the Vietnamese dislike of Americans in Vietnam.

Article Draft, Bob Schieffer

Bob Schieffer Vietnam War Collection

Bob Schieffer's notes of events that occured during a battle in Vietnam.

Article Draft, Bob Schieffer

Bob Schieffer Vietnam War Collection

Article draft by Bob Schieffer about the Vietnamese dislike of Americans in Vietnam.

Exploring The Impact Of Inpatient Mental Health Care On Adolescents, Alexandria M. Mckahan

2025 Fall Honors Capstones Projects - Archive

Adolescent psychiatric hospitalizations continue to rise, yet there is limited research on which daily practices inside inpatient units genuinely support engagement and recovery. This project examined how structure, staff tone, and therapeutic programming influence adolescents’ participation and emotional stability within a real inpatient setting. The study focused on three questions: how structured routines affect recovery, what challenges staff face when supporting adolescents with complex needs, and how adolescents’ engagement patterns reflect their perception of care. Using a mixed-methods case study at Mesa Springs Behavioral Health Hospital, I conducted approximately twenty field observations, semi-structured staff interviews, and descriptive engagement tracking across …

Healing Through History, Nancy Baker Jones

Journal of Texas History

This is the written transcription of the author’s closing plenary address to the inaugural conference of the Alliance for Texas History, May 17, 2025. Its purpose is to put into both broad and personal historical contexts the events of 2023 and 2024 that led to the founding of the Alliance for Texas History. It concludes that, despite the difficulties of those events for her and for many other historians of Texas, history offers a potentially healing context for moving forward.

Letter To Bob From Amon G. Carter Jr., Amon G. Carter Jr.

Bob Schieffer Vietnam War Collection

Letter to Bob Schieffer from Amon G. Carter Jr. asking for Propaganda leaflets, March 30, 1966.

Exploring The Association Between Nurse Characteristics And Intent To Leave Their Current Position In Counties With Rural Hospital Closures, Caroline A. King

2025 Fall Honors Capstones Projects - Archive

Increased rural hospital closures and nursing burnout may lead to greater morbidity/mortality for rural residents. Current literature fails to capture whether rural hospital closures influence nurses’ intent to leave their current position. In this cross-sectional study, descriptive and correlational statistical analyses were conducted on survey responses from a sample of nurses who lived in a rural county that experienced a hospital closure. 66% of nurses stated that, at one point, they had considered leaving their primary nursing position. Logistic regression model results revealed that nurse-reported age and gender were significant predictors of a nurse’s intention to leave their current position. …

Patent Searching With Uspto, Derwent Innovation And Lens.Org, Ibis Anette Moreno-Lozano

Day Family Research Lab Workshop Series

No abstract provided.

Letter From Clifford To Bob, Clifford Watters Williams

Bob Schieffer Vietnam War Collection

Letter from Pastor Clifford W. Williams to Bob Schieffer, February 17, 1966.

All Of Us Live In Texas, But Our Friends Hang Their Hats In New Zealand, Augusta Arata, Irene L. Flores, Angel Castillo, Robert Hoilman, Donald D. Sanders Ii

Sociology and Anthropology Student Research - Archive

Cultural similarities and differences between New Zealand and Texas through an anthropological perspective. The zine focuses on cuisine, sports, consumerism, and lifestyle choices.