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Niclosamide Induces Protein Ubiquitination And Inhibits Multiple Pro-Survival Signaling Pathways In The Human Glioblastoma U-87 Mg Cell Line, Benxu Cheng, Liza Doreen Morales, Yonghong Zhang, Shizue Mito, Andrew Tsin Sep 2017

Niclosamide Induces Protein Ubiquitination And Inhibits Multiple Pro-Survival Signaling Pathways In The Human Glioblastoma U-87 Mg Cell Line, Benxu Cheng, Liza Doreen Morales, Yonghong Zhang, Shizue Mito, Andrew Tsin

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Glioblastoma is the most common and lethal malignant primary brain tumor for which the development of efficacious chemotherapeutic agents remains an urgent need. The anti-helminthic drug niclosamide, which has long been in use to treat tapeworm infections, has recently attracted renewed interest due to its apparent anticancer effects in a variety of in vitro and in vivo cancer models. However, the mechanism(s) of action remains to be elucidated. In the present study, we found that niclosamide induced cell toxicity in human glioblastoma cells corresponding with increased protein ubiquitination, ER stress and autophagy. In addition, niclosamide treatment led to down-regulation of …

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Understanding The Uncanny: Both Atypical Features And Category Ambiguity Provoke Aversion Toward Humanlike Robots, Megan K. Strait, Victoria A. Floerke, Wendy Ju, Keith Maddox, Jessica D. Remedios, Malte F. Jung, Heather L. Urry Aug 2017

Understanding The Uncanny: Both Atypical Features And Category Ambiguity Provoke Aversion Toward Humanlike Robots, Megan K. Strait, Victoria A. Floerke, Wendy Ju, Keith Maddox, Jessica D. Remedios, Malte F. Jung, Heather L. Urry

Computer Science Faculty Publications

Robots intended for social contexts are often designed with explicit humanlike attributes in order to facilitate their reception by (and communication with) people. However, observation of an “uncanny valley”—a phenomenon in which highly humanlike entities provoke aversion in human observers—has lead some to caution against this practice. Both of these contrasting perspectives on the anthropomorphic design of social robots find some support in empirical investigations to date. Yet, owing to outstanding empirical limitations and theoretical disputes, the uncanny valley and its implications for human-robot interaction remains poorly understood. We thus explored the relationship between human similarity and people's aversion toward …

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The Rider (2017-08-28), Jesus Sanchez Aug 2017

The Rider (2017-08-28), Jesus Sanchez

The Rider Archives

Vol.3 No.1

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Cytidine Deaminase As A Molecular Target In Cancer: An Insight, Claudia A. Almaraz, Debasish Bandyopadhyay Aug 2017

Cytidine Deaminase As A Molecular Target In Cancer: An Insight, Claudia A. Almaraz, Debasish Bandyopadhyay

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Cancer is one of the leading causes of death globally. Although more than 400 varieties of cancer have been reported, based on cell lines, still the actual reason of all types of cancer is not very clear. Several internal and external factors have been identified and the study is ongoing. Up to now about 73 proteins have been identified that are capable to influence directly various phases of cancer including mutation, cell proliferation, invasion, angiogenesis, and metastasis. Cytidine deaminase is one of the important proteins that is responsible for various types of cancer that includes gastric, liver, biliary tract, bladder, …

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Biomedical Research Careers Pipeline In A Southern Hispanic-Serving Institution (Hsi): Perspectives Of Faculty And Students On Efficacy Of Mentoring Workshops, Ming-Tsan P. Lu, Stacey Lee Gonzalez, Yuridia Munoz, Luis V. Colom Aug 2017

Biomedical Research Careers Pipeline In A Southern Hispanic-Serving Institution (Hsi): Perspectives Of Faculty And Students On Efficacy Of Mentoring Workshops, Ming-Tsan P. Lu, Stacey Lee Gonzalez, Yuridia Munoz, Luis V. Colom

Teaching and Learning Faculty Publications

The purpose of the study was to investigate the efficacy of the Mentoring Workshops for students and faculty. College student and faculty participants’ perceptions of competencies, abilities, beliefs, and attitudes through the study university’s mentoring workshops were reported. The studies were exploratory in nature, leading the investigators to conduct pre-post surveys. Findings suggested that students and faculty had a positive perception of the mentoring workshops’ effectiveness. Faculty provided suggestions, such as making the workshops longer, providing case studies, and holding future mentoring workshops, were reported for enhancing the effectiveness of the mentoring workshops.

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Biocidal Defeat Agents Produced By Silver-Iodine Nanoenergetic Gas Generators, Ivan Davila Aug 2017

Biocidal Defeat Agents Produced By Silver-Iodine Nanoenergetic Gas Generators, Ivan Davila

Theses and Dissertations

Nanostructured aluminum (Al), iodine pentoxide (I2O5) nano-rods, and silver oxide (Ag2O) nanoparticles, (Al-I2O5-Ag 2O) were used to compose the ternary thermite composition that serves as a Nanoenergetic Gas Generator (NGG). This composition produces biocidal gases giving the mixture the ability to destroy highly pathogenic microorganisms or bacteria. The dissemination of the biocidal gas in combustion chamber was observed using a high-speed camera. The testing of NGG combustion process against the living Escherichia coli (E.coli) K-12 strain cells, that were cultivated/placed on the sample/chamber surfaces, demonstrated that iodine and silver atoms clouds were deposited to the bacteria surface. The 10/75/15 wt …

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Algan/Gan Hemt By Magnetron Sputtering System, Roman Garcia Perez Aug 2017

Algan/Gan Hemt By Magnetron Sputtering System, Roman Garcia Perez

Theses and Dissertations

In this thesis, the growth of the semiconductor materials AlGaN and GaN is achieved by magnetron sputtering for the fabrication of High Electron Mobility Transistors (HEMTs). The study of the deposited nitrides is conducted by spectroscopy, diffraction, and submicron scale microscope methods. The preparation of the materials is performed using different parameters in terms of power, pressure, temperature, gas, and time. Silicon (Si) and Sapphire (Al2O3) wafers are used as substrates. The chemical composition and surface topography of the samples are analyzed to calculate the materials atomic percentages and to observe the devices surface. The instruments used for the semiconductors …

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Development Of Lower Rio Grande River Water Quality Transportation Numerical Model For Bi-National River Management, Jose O. Gonzalez Aug 2017

Development Of Lower Rio Grande River Water Quality Transportation Numerical Model For Bi-National River Management, Jose O. Gonzalez

Theses and Dissertations

Traditionally, water quality modelling has focused on modelling individual water bodies. However, water quality management problems must be analyzed at the larger scale to include influences from various water bodies that are interconnected. This paper provides a study on the hydrologic and quality transportation calculation by developing a hydrodynamic (unsteady state) channel routing model using a water-balanced approach. A one dimension Lagrangian river model was developed and applied to the 210 plus miles for the lower Rio Grande River Basin from the Falcon Dam to the head water of Brownsville that pours onto the Gulf of Mexico. This model can …

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Molecular Dynamics Simulations Of Dna Duplex Stretching, Ramin Salimi Aug 2017

Molecular Dynamics Simulations Of Dna Duplex Stretching, Ramin Salimi

Theses and Dissertations

Single-molecule DNA stretching experiments is a an extremely rigorous method to investigate mechanical properties of DNA and how DNA molecule binding to proteins, and other small molecules works. In these experiments, double-stranded DNA molecules are stretched by a force applied to opposite ends of the DNA, e.g., in an atomic force microscope or an optical tweezers instrument. Here we study the stretching behavior of the DNA duplex d(CGCAAAAAAGCG) 2 by molecular dynamics simulations. In particular, we calculate the change in free energy ∆F = ∆U − T ∆S as the DNA duplex is stretched. We seek to show that employing …

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Hankel Partial Contraction, Contractive Completion, Moore-Penrose Inverse, Extremal Case, Manuel A. Villarreal Jr. Aug 2017

Hankel Partial Contraction, Contractive Completion, Moore-Penrose Inverse, Extremal Case, Manuel A. Villarreal Jr.

Theses and Dissertations

In this article we find concrete necessary and sufficient conditions for the existence of contractive completions of Hankel partial contractions of size 3x3 non-extremal case.

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Upscaling Capillary Pressure–Saturation Functions Using Different Reference Pressure Elevations, Chu-Lin Cheng, S. Clark Cropper, Edmund Perfect, Larry Mckay, Misun Kang Aug 2017

Upscaling Capillary Pressure–Saturation Functions Using Different Reference Pressure Elevations, Chu-Lin Cheng, S. Clark Cropper, Edmund Perfect, Larry Mckay, Misun Kang

School of Earth, Environmental, & Marine Sciences Faculty Publications

Choice of reference pressure elevation (RPE) on average effective saturation–capillary pressure functions, 〈〉(ψ), was investigated for monotonic drainage of homogeneous porous media. Nine columns of Flint sand with heights ranging from 4.3 to 55.0 cm were prepared. Measured 〈〉(ψ) functions were determined gravimetrically using the hanging water column method. Predicted 〈〉(ψ) functions were obtained by upscaling point function parameters determined by neutron radiographic imaging of a single drainage experiment. Bottom and midpoint RPEs resulted in the inaccurate parameterization of 〈〉(ψ) functions for tall columns. A top RPE produced accurate upscaled functions for all column heights. To evaluate the overall performance …

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Impact Of Salinity Change On Water Quality Variables From The Sediment Of An Artificial Lake Under Anaerobic Conditions, Tae-Hoon Kim, James Jihoon Kang, Sang Hyun Kim, I-Song Choi, Kwang-Hyeon Chang, Jong Min Oh, Ki-Hyun Kim Aug 2017

Impact Of Salinity Change On Water Quality Variables From The Sediment Of An Artificial Lake Under Anaerobic Conditions, Tae-Hoon Kim, James Jihoon Kang, Sang Hyun Kim, I-Song Choi, Kwang-Hyeon Chang, Jong Min Oh, Ki-Hyun Kim

School of Earth, Environmental, & Marine Sciences Faculty Publications

Artificial reservoirs are created by dike construction in coastal areas to secure the agricultural water supply on the west coast of South Korea. These systems are found to retain brackish characteristics until total desalination is achieved. To evaluate the effects of salinity on the organic substances released from the sediment, a laboratory water-sediment column experiment was conducted to assess associated changes in water quality variables such as the sediment oxygen demand (SOD), chemical oxygen demand (COD), and concentrations of nitrogen (N) and phosphorus (P). Under high salinity conditions, the release of N from the sediment was promoted with the enhancement …

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Analyzing The Relationship Between Human Behavior And Indoor Air Quality, Beiyu Lin, Yibo Huangfu, Nathan Lima, Bertram Jobson, Max Kirk, Patrick O’Keeffe, Shelley N. Pressley, Von Walden, Brian Lamb, Diane J. Cook Aug 2017

Analyzing The Relationship Between Human Behavior And Indoor Air Quality, Beiyu Lin, Yibo Huangfu, Nathan Lima, Bertram Jobson, Max Kirk, Patrick O’Keeffe, Shelley N. Pressley, Von Walden, Brian Lamb, Diane J. Cook

Computer Science Faculty Publications

In the coming decades, as we experience global population growth and global aging issues, there will be corresponding concerns about the quality of the air we experience inside and outside buildings. Because we can anticipate that there will be behavioral changes that accompany population growth and aging, we examine the relationship between home occupant behavior and indoor air quality. To do this, we collect both sensor-based behavior data and chemical indoor air quality measurements in smart home environments. We introduce a novel machine learning-based approach to quantify the correlation between smart home features and chemical measurements of air quality, and …

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Nanostructured Functional Materials For Advanced Three-Dimensional (3d) Solar Cells, Jared Jaksik, H. Justin Moore, Tarek Trad, Okenwa Okoli, M. Jasim Uddin Aug 2017

Nanostructured Functional Materials For Advanced Three-Dimensional (3d) Solar Cells, Jared Jaksik, H. Justin Moore, Tarek Trad, Okenwa Okoli, M. Jasim Uddin

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Advancements in dye-sensitized solar cell (DSSC) technology are occurring at an ever-increasing rate, as the development of novel carbon-based materials, the increasing research into new 3D surface morphologies and cell design, and the focus on the development of new sensitizers and electrolytes have allowed many new possibilities for DSSCs. Solar cells that are three-dimensionally structured offer significant advantages over traditional crystalline / semi-crystalline panels in that they can convert incident photons that strike them at large incident angles, can be flexible / used in applications which require non-rigid materials, and can be substantially cheaper to produce than traditional panels, especially …

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Wayne Booth's Rhetoric Of Pluralism, William John Ordeman Aug 2017

Wayne Booth's Rhetoric Of Pluralism, William John Ordeman

Theses and Dissertations

In this thesis, I will be examining the arguments Wayne C. Booth put forth for Pluralism in rhetorical studies. I will show how Booth believed that ethical criticism, not only in literary criticism but in all disputation, must take place in order for us to understand each other and objective values. Booth believed that our differing opinions and arguments may not be reconcilable, but by employing “listening rhetoric”, a method of paying close attention to the arguments of those who disagree with us, we can arrive at truths that are shared within a community. I juxtapose Booth with both Positivists …

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An Extended Jahn-Teller Hamiltonian For Large-Amplitude Motion: Application To Vibrational Conical Intersections In Ch3sh And Ch3oh, Mahesh B. Dawadi, Bishnu P. Thapaliya, David S. Perry Jul 2017

An Extended Jahn-Teller Hamiltonian For Large-Amplitude Motion: Application To Vibrational Conical Intersections In Ch3sh And Ch3oh, Mahesh B. Dawadi, Bishnu P. Thapaliya, David S. Perry

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

An extended Jahn-Teller Hamiltonian is presented for the case where the (slow) nuclear motion extends far from the symmetry point and may be described approximately as motion on a sphere. Rather than the traditional power series expansion in the displacement from the C3v symmetry point, an expansion in the spherical harmonics is employed. Application is made to the vibrational Jahn-Teller effect in CH3XH, with X = S, O, where the equilibrium CXH angles are 83° and 72°, respectively. In addition to the symmetry-required conical intersection (CI) at the C3v symmetry point, ab initio calculations reveal sets of six symmetry-allowed vibrational …

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Maritime Cyber Security: What About Digital Forensics?, Scott Blough, Gordon A. Crews Jul 2017

Maritime Cyber Security: What About Digital Forensics?, Scott Blough, Gordon A. Crews

Criminal Justice Faculty Publications

No abstract provided.

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Search For High-Energy Neutrinos From Gravitational Wave Event Gw151226 And Candidate Lvt151012 With Antares And Icecube, A. Albert, M. André, M. Anghinolfi, Teviet Creighton, Mario C. Diaz, Soma Mukherjee, Volker Quetschke, Malik Rakhmanov Jul 2017

Search For High-Energy Neutrinos From Gravitational Wave Event Gw151226 And Candidate Lvt151012 With Antares And Icecube, A. Albert, M. André, M. Anghinolfi, Teviet Creighton, Mario C. Diaz, Soma Mukherjee, Volker Quetschke, Malik Rakhmanov

Physics & Astronomy Faculty Publications

The Advanced LIGO observatories detected gravitational waves from two binary black hole mergers during their first observation run (O1). We present a high-energy neutrino follow-up search for the second gravitational wave event, GW151226, as well as for gravitational wave candidate LVT151012. We find two and four neutrino candidates detected by IceCube, and one and zero detected by Antares, within ±500  s around the respective gravitational wave signals, consistent with the expected background rate. None of these neutrino candidates are found to be directionally coincident with GW151226 or LVT151012. We use nondetection to constrain isotropic-equivalent high-energy neutrino emission from GW151226, adopting …

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Search For Intermediate Mass Black Hole Binaries In The First Observing Run Of Advanced Ligo, B. P. Abbott, R. Abbott, T. D. Abbott, F. Acernese, K. Ackley, Teviet Creighton, Mario C. Diaz, Soma Mukherjee, Volker Quetschke, Malik Rakhmanov Jul 2017

Search For Intermediate Mass Black Hole Binaries In The First Observing Run Of Advanced Ligo, B. P. Abbott, R. Abbott, T. D. Abbott, F. Acernese, K. Ackley, Teviet Creighton, Mario C. Diaz, Soma Mukherjee, Volker Quetschke, Malik Rakhmanov

Physics & Astronomy Faculty Publications

During their first observational run, the two Advanced LIGO detectors attained an unprecedented sensitivity, resulting in the first direct detections of gravitational-wave signals produced by stellar-mass binary black hole systems. This paper reports on an all-sky search for gravitational waves (GWs) from merging intermediate mass black hole binaries (IMBHBs). The combined results from two independent search techniques were used in this study: the first employs a matched-filter algorithm that uses a bank of filters covering the GW signal parameter space, while the second is a generic search for GW transients (bursts). No GWs from IMBHBs were detected; therefore, we constrain …

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Phenotypic Variations In Violence Involvement: Results From The National Longitudinal Study Of Adolescent Health, Igor Ryabov Jul 2017

Phenotypic Variations In Violence Involvement: Results From The National Longitudinal Study Of Adolescent Health, Igor Ryabov

Sociology Faculty Publications

Numerous studies suggest that our society is stratified not only by race and class, but also by phenotypic characteristics. The main objective of the present investigation was, using the National Longitudinal Study of Adolescent Health, to elucidate the link between phenotype and violence involvement. Two outcomes were examined: being a perpetrator of violence and criminal justice system contact. Cross-sectional and longitudinal analyses were conducted on Asian, black and Hispanic respondents and as well as on the subsample of siblings. Independent variables included phenotype, socioeconomic status, other family, peer and neighborhood effects. Notwithstanding a certain degree of heterogeneity of outcomes across …

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Latino Youth’S Out-Of-School Math And Science Experiences: Impact On Teacher Candidates, Maria E. Diaz, Kathy Bussert-Webb Jul 2017

Latino Youth’S Out-Of-School Math And Science Experiences: Impact On Teacher Candidates, Maria E. Diaz, Kathy Bussert-Webb

Bilingual and Literacy Studies Faculty Publications

This qualitative study examines the learning and interaction processes between Latino/a teacher candidates (TCs) and youth during a community service-learning program involving science and math. Knowing and affirming nondominant youth‟s strengths are essential from funds of knowledge and Third Space perspectives. Participants were 11 TCs and their tutees, 30 youth in first through tenth grades. The study took place in a Texas border colonia, or unincorporated settlement lacking basic services. Data sources were participant observations, youth‟s interviews and TCs‟ pre- and final reflections, rapport- building analyses, a focus group, and lesson plans. We found TCs incorporated the youth‟s funds to …

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Thermal Consolidation Of Dredge Sand For Artificial Reef Formations, Alexandro Trevino Jul 2017

Thermal Consolidation Of Dredge Sand For Artificial Reef Formations, Alexandro Trevino

Theses and Dissertations

Coral Reef ecosystems have degraded over years due to a variety of environmental issues such as ocean acidification. The continuous stress has detrimental effects on coral reef ecosystems that can possibly lead to the loss of the ecosystem. Our research aims to construct a prototype of an artificial reef by consolidating dredge sand from the ship channels of South Texas. Consolidation is achieved through an aluminum polytetrafluoroethylene self-propagating high temperature process that yields a solid formation to mimic the physical properties of coral reef structures. Using thermodynamic calculations, the variation of initial components was determined that reached an adiabatic temperature …

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Removal Of Lead And Arsenic From Aqueous Solution By Biochar Produced From Locally-Sourced Biomass, Sergio I. Mireles Jul 2017

Removal Of Lead And Arsenic From Aqueous Solution By Biochar Produced From Locally-Sourced Biomass, Sergio I. Mireles

Theses and Dissertations

This study evaluated the effectiveness of four adsorbent materials, pyrolyzed corn stover, orange peel, pistachio shell, and magnetic biochar for their ability to adsorb lead (Pb) and arsenic (As III, As V) from aqueous solution. An increase in adsorption was seen as the pH of the solution increased from pH 2 to pH 6. Magnetic orange peel biochar with Fe3O4 particles precipitated on the surface of biochar was synthetized by co-precipitation and used for arsenic adsorption. Initial pH value had an influence on the adsorption behavior of As (III) and As (V). In the pH range of 2–6, As (V) …

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Exploring Bilingual Teachers' Beliefs About Academic Language Development In Mathematics Teaching: Implications For Bilingual Teachers' Professional Development, Viola Canales-Vela Jul 2017

Exploring Bilingual Teachers' Beliefs About Academic Language Development In Mathematics Teaching: Implications For Bilingual Teachers' Professional Development, Viola Canales-Vela

Theses and Dissertations

The achievement of mathematics within Hispanic youth is of great concern across the nation. In order to improve student achievement in mathematics, the nature of a mathematics teacher’s complex belief system must be understood (McGee &Wang, 2014). The purpose of this exploratory qualitative study is to investigate the K-5 bilingual teachers’ beliefs about how to develop the academic language of mathematics in Spanish and English in the context of dual language programs at the elementary school level and bilingual teachers’ perceptions on the impact of professional development design for bilingual teachers to meet the needs of their students’ academic language …

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Can Ecosystem Functional Recovery Be Traced To Decomposition And Nitrogen Dynamics In Estuaries Of The Lower Laguna Madre, Texas?, Mario A. Marquez, Alejandro Fierro-Cabo, Carlos E. Cintra-Buenrostro Jul 2017

Can Ecosystem Functional Recovery Be Traced To Decomposition And Nitrogen Dynamics In Estuaries Of The Lower Laguna Madre, Texas?, Mario A. Marquez, Alejandro Fierro-Cabo, Carlos E. Cintra-Buenrostro

School of Earth, Environmental, & Marine Sciences Faculty Publications

The biggest incentive to attempt the restoration and protection of estuaries is their widely acknowledged ecological and economic importance. Assessing estuary health and recovery can most accurately come from examining ecosystem processes. The purpose of this study was to explore the potential of mass loss and nitrogen (N) dynamics during leaf litter decomposition, to detect signs of functional recovery in two estuarine systems in south Texas. Submerged litterbags with black mangrove (Avicennia germinans) leaves were retrieved at various dates over 320 days. Decomposition was about 50% slower in one of the recovering systems compared to a reference site. …

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Sorption Of Cr(Iii) And Cr(Vi) To K2mn4o9 Nanomaterial A Study Of The Effect Of Ph, Time, Temperature And Interferences, J. P. Valle, B. Gonzalez, J. Schulz, D. Salinas, U. Romero, Diego F. Gonzalez, Carolina Valdes, J. M. Cantu, Thomas Eubanks, Jason Parsons Jul 2017

Sorption Of Cr(Iii) And Cr(Vi) To K2mn4o9 Nanomaterial A Study Of The Effect Of Ph, Time, Temperature And Interferences, J. P. Valle, B. Gonzalez, J. Schulz, D. Salinas, U. Romero, Diego F. Gonzalez, Carolina Valdes, J. M. Cantu, Thomas Eubanks, Jason Parsons

School of Earth, Environmental, & Marine Sciences Faculty Publications

A Rancieite type material (K2Mn4O9) nanomaterial was synthesized and tested for the removal of chromium (III) and chromium (VI) from aqueous solutions. The synthesized nanomaterial was characterized using powder XRD and SEM. XRD showed weak diffraction peaks at only at the angles associated with K2Mn4O9. The SEM corroborated that the nanoparticles were present; however, the nanoparticles were clustered into larger aggregates. Batch studies were performed to determine the optimum pH, capacity, time dependency, interferences, and the thermodynamics of the binding. The optimum pH for the binding of Cr(III) and Cr(VI) were determined to be pH 5 and pH 2, respectively. …

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Using Pedagogical Tools To Help Hispanics Be Successful In Computer Science, Rodger Irish Jul 2017

Using Pedagogical Tools To Help Hispanics Be Successful In Computer Science, Rodger Irish

Theses and Dissertations

Irish, Rodger, Using Pedagogical Tools to Help Hispanics Be Successful in Computer Science. Master of Science (MS), July 2017, 68 pp., 4 tables, 2 figures, references 48 titles. Computer science (CS) jobs are a growing field and pay a living wage, but the Hispanics are underrepresented in this field. This project seeks to give an overview of several contributing factors to this problem. It will then explore some possible solutions to this problem and how a combination of some tools (teaching methods) can create the best possible outcome. It is my belief that this approach can produce successful Hispanics to …

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Identification Of Chemical Compounds That Inhibit Protein Synthesis In Pseudomonas Aeruginosa, Stephanie O. Palmer, Yanmei Hu, Megan Keniry, James M. Bullard Jul 2017

Identification Of Chemical Compounds That Inhibit Protein Synthesis In Pseudomonas Aeruginosa, Stephanie O. Palmer, Yanmei Hu, Megan Keniry, James M. Bullard

School of Integrative Biological & Chemical Sciences Faculty Publications

Four inhibitory compounds were identified using a poly-uridylic acid (polyU) mRNA-directed aminoacylation/translation (A/T) protein synthesis system composed of phenylalanyl-tRNA synthetases (PheRS), ribosomes, and ribosomal factors from Pseudomonas aeruginosa in an in vitro screen of a synthetic compound library. The compounds were specific for inhibition of bacterial protein synthesis. In enzymatic assays, the compounds inhibited protein synthesis with IC50 values ranging from 20 to 60 μM. Minimum inhibitory concentrations (MICs) were determined in cultures for a panel of pathogenic organisms, including Enterococcus faecalis, Escherichia coli, Haemophilus influenzae, P. aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae. All the compounds were observed to have …

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A Novice Bilingual Teacher’S Journey: Teacher’S Noticing As A Pathway To Negotiate Contradictory Teaching Discourses, Sandra I. Musanti Jun 2017

A Novice Bilingual Teacher’S Journey: Teacher’S Noticing As A Pathway To Negotiate Contradictory Teaching Discourses, Sandra I. Musanti

Bilingual and Literacy Studies Faculty Publications

This qualitative case study investigates a fourth grade novice bilingual teacher’s repertoire of practice during her first year of teaching. Drawing on recent work on teacher noticing, the study explores how the teacher negotiates prevailing bilingual education discourses. Two themes are discussed: how this novice teacher embraced bilingual teaching while questioning practices and policies and how she negotiated contradictions through multiple attempts to redefine her teaching practices. Findings show how the teacher’s ability to notice framed her possibility to bridge her understandings about teaching, her critical pedagogical discourse, and the contextual contradictory discourses predominant in her school about bilingual education.

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On Orientation Memory In High Density Polyethylene - Carbon Nanofibers Composites, Mircea Chipara, Brian Jones, Dorina M. Chipara, Jianhua Li, Karen Lozano, Shah Valloppilly, David Sellmyer Jun 2017

On Orientation Memory In High Density Polyethylene - Carbon Nanofibers Composites, Mircea Chipara, Brian Jones, Dorina M. Chipara, Jianhua Li, Karen Lozano, Shah Valloppilly, David Sellmyer

Physics & Astronomy Faculty Publications

An orientation memory effect in high density polyethylene (HDPE) filled with vapor grown carbon nanofibers (VGCNF) is reported. Two-dimensional X-ray (2DXR) confirmed the reorientation of HDPE crystallites upon the uniaxial stretching of HDPE and HDPE filled by VGCNFs. This anisotropy of 2DXR spectra was decreased by heating all stretched samples (loaded or not loaded by VGCNFs) from room to the melting temperature of HDPE. Upon cooling these samples to room temperature, it was noticed that only the nanocomposite retained a weak partial (uniaxial) order, while HDPE showed a completely isotropic 2DXR spectrum. It was concluded that during the stretching of …

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