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Foraging Areas Of Breeding Adult Sooty Terns Onychoprion Fuscatus On Bird Island, Seychelles., Jessica L. Neumann, Ruth E. Dunn, Malcolm A. C. Nicoll, Christine S. Larose, Chris Foster, Gary Brodin, Chris J. Feare Aug 2026

Foraging Areas Of Breeding Adult Sooty Terns Onychoprion Fuscatus On Bird Island, Seychelles., Jessica L. Neumann, Ruth E. Dunn, Malcolm A. C. Nicoll, Christine S. Larose, Chris Foster, Gary Brodin, Chris J. Feare

Marine Ornithology

The foraging areas used by adult Sooty Terns Onychoprion fuscatus during incubation and early chick-rearing on Bird Island, Seychelles, were investigated using small GPS loggers. Birds departed the colony mainly during the night and foraged by day. Most foraging trips were completed within 24 hr, but during incubation the longest duration recorded was seven days and 14 hr (during which the bird travelled 2,783 km and reached a maximum of 692 km from the colony). Departures were generally in an arc from south (180°) through westerly to 40°. Sooty Terns foraged frequently in waters over the Seychelles Bank shelf break, …


First Gps Tracking Of The Black Storm Petrel Hydrobates Melania., Jorge Cristerna, Gemma Abaunza, Joel Aarón López-Hernández, Cecilia Soldatini, Yuri Vladimir Albores-Barajas, Federico De Pascalis, Jacopo G. Cecere Aug 2026

First Gps Tracking Of The Black Storm Petrel Hydrobates Melania., Jorge Cristerna, Gemma Abaunza, Joel Aarón López-Hernández, Cecilia Soldatini, Yuri Vladimir Albores-Barajas, Federico De Pascalis, Jacopo G. Cecere

Marine Ornithology

The research reported here, conducted at Archipiélago de Espíritu Santo National Park, Baja California Sur, Mexico, establishes the first successful application of biologging on a Black Storm Petrel Hydrobates melania. Results yielded preliminary insights into this population's marine movements during nesting. The device used, weighing less than 3% of the bird's body mass, recorded a 181-km foraging trip. Subsequent trajectory analysis indicated navigation behavior that potentially was optimized to use crosswind assistance. The individual showed no weight loss post-retrieval, a finding that suggests this method is viable and unharmful, demonstrating the feasibility of using miniaturized tracking devices to unravel …


Predicting Suitable Marine Habitat For Pink-Footed Shearwaters Ardenna Creatopus In The Waters Along The Pacific Coast Of Canada., Sonya A. Pastran, Patrick D. O’Hara, Kenneth H. Morgan, Caroline H. Fox, W. Eric Gross Aug 2026

Predicting Suitable Marine Habitat For Pink-Footed Shearwaters Ardenna Creatopus In The Waters Along The Pacific Coast Of Canada., Sonya A. Pastran, Patrick D. O’Hara, Kenneth H. Morgan, Caroline H. Fox, W. Eric Gross

Marine Ornithology

Anthropogenic activities are threatening global marine ecosystems, with seabirds representing a vulnerable group that has experienced pronounced population declines in recent decades. The ability to identify important marine areas for vulnerable seabirds is fundamental to conservation initiatives. The Pink-footed Shearwater Ardenna creatopus (listed as Endangered in Canada) breeds only in Chile, but during the non-breeding season, it ranges northward to waters off Canada's Pacific coast and the northern Gulf of Alaska. Using at-sea survey data spanning from 1992 to 2019, we examined the relationship between the species' distribution and environmental variables using a two-step generalized additive model approach. Cross-validation with …


Tasmanian Records Of Vagrant Penguins, 1991–2025., Eric J. Woehler Aug 2026

Tasmanian Records Of Vagrant Penguins, 1991–2025., Eric J. Woehler

Marine Ornithology

During the period 01 January 1991 to 31 August 2025, there were 274 records of vagrant penguins in Tasmania. These records represented three genera: Aptenodytes, Pygoscelis, and Eudyptes. The most frequently reported species were Fiordland Penguin E. pachyrhynchus, Royal Penguin E. schlegeli, and King Penguin A. patagonicus. High numbers of records were reported from 10 years, with a peak in 1999 and a lower peak in 2023. Records from January to March accounted for approximately 42% of all vagrant penguin occurrences and corresponded with the arrival of pre-moult birds of all ages. A range …


Comparative Diet Analysis Of Three Larid Species Nesting At Isla Rasa, Gulf Of California, Mexico., Enriqueta Velarde, Lloyd T. Findley Aug 2026

Comparative Diet Analysis Of Three Larid Species Nesting At Isla Rasa, Gulf Of California, Mexico., Enriqueta Velarde, Lloyd T. Findley

Marine Ornithology

Isla Rasa, situated in highly productive waters of the Gulf of California, has the largest nesting colony of Royal Terns Thalasseus maximus (as many as 17,000 individuals) in the Mexican Pacific, sharing this site with 300,000 Elegant Terns T. elegans and 260,000 Heermann's Gulls Larus heermanni. During eight breeding seasons between 1996 and 2011, we found that the Royal Tern diet contained over twice the number of prey species as the other two seabirds' diets: the Royal Tern's diet included 36 species of fishes, in 20 families, and pelagic squat lobster Grimothea planipes, whereas the Elegant Tern and …


Evidence For Colony Attendance By Immature Streaked Shearwaters Calonectris Leucomelas During The Chick-Rearing Period., Helen M. Pružina, Akiko Shoji, Masaki Shirai, Sakiko Matsumoto, Ken Yoda, Annette L. Fayet Aug 2026

Evidence For Colony Attendance By Immature Streaked Shearwaters Calonectris Leucomelas During The Chick-Rearing Period., Helen M. Pružina, Akiko Shoji, Masaki Shirai, Sakiko Matsumoto, Ken Yoda, Annette L. Fayet

Marine Ornithology

Many seabird species have a long breeding-deferral period, during which individuals mature and spend most of their time at sea, making them particularly difficult to study. In some species, immatures are known to start visiting colonies before reaching adulthood, presumably to learn the behaviours required to secure a nest and mate for future breeding. However, immature colony attendance remains undocumented in many species, particularly those that are difficult to observe, such as nocturnal, cavity-nesting species and species in which immatures are indistinguishable from adults. Here, we studied the attendance patterns and behaviour of Streaked Shearwaters Calonectris leucomelas on Awashima Island, …


First Record Of Leucism In Kerguelen Shag Leucocarbo Verrucosus, Kevin Guille Aug 2026

First Record Of Leucism In Kerguelen Shag Leucocarbo Verrucosus, Kevin Guille

Marine Ornithology

The first case of leucism in the Kerguelen Shag Leucocarbo verrucosus was observed on Mayes Island, Kerguelen Archipelago, in the southern Indian Ocean between October 2021 and November 2022. The individual exhibited extensive white plumage with scattered black feathers while maintaining normal eye pigmentation, consistent with leucism rather than albinism. Despite exhibiting typical behavior and social interactions, no breeding activity was recorded. This observation highlights the occurrence of pigment abnormalities in sub-Antarctic seabirds and underscores the importance of continued monitoring to better understand their ecological or genetic implications.


Satellite Tracking Of Galapagos Petrel Pterodroma Phaeopygia Reveals Distribution And Movements During Chick Rearing., Carolina B. Proaño, Sebastian M. Cruz, Josh Adams, Martin Wikelski Aug 2026

Satellite Tracking Of Galapagos Petrel Pterodroma Phaeopygia Reveals Distribution And Movements During Chick Rearing., Carolina B. Proaño, Sebastian M. Cruz, Josh Adams, Martin Wikelski

Marine Ornithology

We tracked 19 adult Galapagos Petrels Pterodroma phaeopygia during the chick-rearing seasons in 2009 and 2010 (Santa Cruz Island [n = 16] and Floreana Island [n = 3]) in the Galápagos Islands, Ecuador. Eight petrels performed 27 complete foraging trips lasting 0.6 to 18.8 days. Short trips (3.2 ± 2.1 days; 785 km; max displacement 671 km) and long trips (10.8 ± 3.9 days; 2,856 km; max displacement 1,034 km) resulted in concentrated use of waters off southern and western Isabela Island and within the Galápagos Marine Reserve (GMR). Less concentrated time extended farther southwest and eastward, in …


Unfamiliar Plumage Aberration Observed On A Razorbill Alca Torda At Machias Seal Island., Daniel Oliker, Antony W. Diamond, Heather L. Major Aug 2026

Unfamiliar Plumage Aberration Observed On A Razorbill Alca Torda At Machias Seal Island., Daniel Oliker, Antony W. Diamond, Heather L. Major

Marine Ornithology

Aberrant plumage variation in seabirds can be caused by both heritable genetic mutations and non-heritable somatic mutations due to environmental stressors. In Razorbills Alca torda, aberrant colouration has been documented four times: three as cases of melanism and one seemingly of leucism, both heritable mutations. Here, we describe the observation and subsequent capture of a Razorbill with an unfamiliar plumage phenotype we hypothesize to be caused by a somatic mutation. To our knowledge, this is the first reported instance of a somatic mutation affecting the plumage of a Razorbill in the primary literature.


Seasonal Variation In Trophic Niche And Resource Use In Great Black-Backed Gulls Larus Marinus., Samuel Langlois Lopez, Nina J. O’Hanlon, Jared Wilson, Rona A. R. Mcgill, Francis Daunt, Elizabeth A. Masden Aug 2026

Seasonal Variation In Trophic Niche And Resource Use In Great Black-Backed Gulls Larus Marinus., Samuel Langlois Lopez, Nina J. O’Hanlon, Jared Wilson, Rona A. R. Mcgill, Francis Daunt, Elizabeth A. Masden

Marine Ornithology

Seabirds experience variable extrinsic and intrinsic pressures throughout the annual cycle that affect their ability to forage. Consequently, their foraging strategies may vary between breeding and non-breeding seasons due to the constraints of central-place foraging during the former. Here, we studied a population of a generalist seabird, the Great Black-backed Gull Larus marinus, breeding at a colony on the Isle of May, Scotland. We quantified seasonal variation in sexual segregation, trophic position, trophic niche width, and resource use by examining stable isotopes in feathers collected from adults. We found no sexual segregation, but we detected population- and individual-level shifts …


Observation Of Black Noddies Anous Minutus Swallowing Coral Pebbles On A Polynesian Atoll., Simon Ducatez, Jayna L. Devore Aug 2026

Observation Of Black Noddies Anous Minutus Swallowing Coral Pebbles On A Polynesian Atoll., Simon Ducatez, Jayna L. Devore

Marine Ornithology

We report the observation of Black Noddies Anous minutus ingurgitating small pieces of coral debris on top of beachrock on the atoll of Tetiʻaroa, 50 km north of Tahiti in French Polynesia.


Assessing The Impact Of Coordinated Mink Culling On Bird Populations On Coastal Islands In Norway., Fredrik R. Staven, Torgeir Nygård Aug 2026

Assessing The Impact Of Coordinated Mink Culling On Bird Populations On Coastal Islands In Norway., Fredrik R. Staven, Torgeir Nygård

Marine Ornithology

The introduction of the non-native American Mink Neogale vison (syn. Neovison vison), a predator of birds and their chicks and eggs, is one of many anthropogenic factors that may be driving the decline of seabird populations in areas where mink are prevalent. Previous studies have shown that ground-nesting birds utilising coastal ecosystems are especially vulnerable. In this study, we investigated changes in seabird and coastal-bound bird populations, focusing on ground-nesting species, and the potential effect from mink culling. Ten locations in the archipelago of Flatanger, a coastal municipality in central Norway, were surveyed, and bird counts from 1991, 2016, …


Important Bird Area Ant 110 Muskegbukta, Queen Maud Land, East Antarctica: A Case Study., Barbara Wienecke Aug 2026

Important Bird Area Ant 110 Muskegbukta, Queen Maud Land, East Antarctica: A Case Study., Barbara Wienecke

Marine Ornithology

The nomination of Important Bird Areas (IBAs) is a useful approach to determine where valuable biodiversity areas occur. In Antarctica, 204 areas have been designated as IBAs, 34 of which contain Emperor Penguin Aptenodytes forsteri colonies. The dynamic nature of the Antarctic environment presents challenges to IBA nominations, particularly for a species such as the Emperor Penguin, whose colonies can shift markedly in location across years. This paper uses IBA ANT 110 Muskegbukta as a case study to explore how changes in local and regional fast ice conditions result in relocation of a colony beyond the nominated IBA boundary. Because …


Atlantic Puffin Fratercula Arctica Mortality Along The Portuguese West Coast In Early 2023., Rute A. Costa, Ana S. Tavares, Francisca V. Hilário, Jorge Vaqueiro, Marisa Ferreira, Sara Sá, Silvia S. Monteiro, Andreia Torres-Pereira, Catarina Eira Aug 2026

Atlantic Puffin Fratercula Arctica Mortality Along The Portuguese West Coast In Early 2023., Rute A. Costa, Ana S. Tavares, Francisca V. Hilário, Jorge Vaqueiro, Marisa Ferreira, Sara Sá, Silvia S. Monteiro, Andreia Torres-Pereira, Catarina Eira

Marine Ornithology

This study presents data about a mortality event involving Atlantic Puffins Fratercula arctica in the central region of Portugal, including information on the species' biometrics. More than 2,000 seabirds were collected from beaches between Lisbon and Matosinhos in January and February 2023, as casualties of a massive wreck. In total 444 Atlantic Puffins (171 live, 273 dead) were found and analysed. Leg bands on some birds indicated that these individuals primarily originated from colonies in Scotland. Of the live puffins that entered the Ecomare Marine Animal Rehabilitation Centre, only 18 survived to be successfully released. We conducted 426 post-mortem examinations …


Diel And Seasonal Patterns Of Markham’S Storm Petrel Hydrobates Markhami In The Atacama Desert, Chile, Maya E. Philipp, Abram B. Fleishman, Jeff Schlueter, Giannira Álvarez, Benjamin Gallardo, Pablo Gutiérrez, Ronny Peredo, Brad Keitt, Fernando Medrano Aug 2026

Diel And Seasonal Patterns Of Markham’S Storm Petrel Hydrobates Markhami In The Atacama Desert, Chile, Maya E. Philipp, Abram B. Fleishman, Jeff Schlueter, Giannira Álvarez, Benjamin Gallardo, Pablo Gutiérrez, Ronny Peredo, Brad Keitt, Fernando Medrano

Marine Ornithology

Markham's Storm Petrel Hydrobates markhami is endemic to the Humboldt Current, breeding inland in Chile and Peru. Its nesting habitat in Atacama Desert saltpeter deposits overlaps with light pollution, roadways, and other anthropogenic disturbances—factors that may impact the species' populations. Owing to its remote nesting locations and nocturnal behavior, finding and monitoring its colonies is challenging. In fact, the first colonies were discovered only recently. In this study, we assessed whether passive acoustic monitoring of this species detects the same activity patterns as active nest monitoring. Acoustic monitors were placed at eight sites within colonies at Caleta Buena (Tarapacá Region) …


Masthead, Marine Ornithology Aug 2026

Masthead, Marine Ornithology

Marine Ornithology

No abstract provided.


Inside Front Cover, Marine Ornithology Aug 2026

Inside Front Cover, Marine Ornithology

Marine Ornithology

No abstract provided.


Book Review: A People Destroyed: New Research On The Roma Genocide, 1941–1945, Elizabeth Graham Jul 2026

Book Review: A People Destroyed: New Research On The Roma Genocide, 1941–1945, Elizabeth Graham

Genocide Studies and Prevention: An International Journal

No abstract provided.


The Aging Muscle Phenotype Of C57bl/6j Wild-Type Mice, Gaurav Shingote Jul 2026

The Aging Muscle Phenotype Of C57bl/6j Wild-Type Mice, Gaurav Shingote

OneUSF Undergraduate Research Conference

Aging causes a slow and progressive loss of muscle fiber number and size. Sarcopenia is termed as an age-related loss of muscle mass and function. Here, we characterized the aging skeletal muscle phenotype of C57Bl/6J wildtype mice. 30 weeks old (young) and 2 years old (aged) C57Bl/6J wildtype male mice were utilized in this study. The body weight and hind leg muscle weight were recorded during collection. The hind leg muscle Tibialis anterior (TA) was OCT embedded, cut at the mid- belly region, and stained with hematoxylin and eosin (H&E) stain as per our previously published protocol. The 20X images …


Efficacy Of Monoclonal Antibody Treatment On Lowering Infectious Disease Burden In U.S. Elderly Patients, Lyndsey M. White, Daniel Johnson, A'Niya Jackson, Laiba Majid Jul 2026

Efficacy Of Monoclonal Antibody Treatment On Lowering Infectious Disease Burden In U.S. Elderly Patients, Lyndsey M. White, Daniel Johnson, A'Niya Jackson, Laiba Majid

OneUSF Undergraduate Research Conference

Older adults in the United States experience a high burden of infectious diseases due to age related immune decline, reduced vaccine responsiveness, and increased comorbidities. Monoclonal antibody therapies are an important strategy for lowering this burden because they provide immediate and highly specific immune protection. This review evaluates the effectiveness of monoclonal antibodies in reducing infectious disease severity in elderly populations and examines how neutrophils and the formation of neutrophil extracellular traps interact with antibody based treatments. Throughout the review, these therapies have been shown to be successful against multiple infectious diseases, and clinical findings suggest that hospitalized elderly or …


Accelerating Protein Engineering: Using Computer Modeling To Identify Beneficial Interleukin-23 (Il-23) Mutations, Andrew S. Chadwell Jul 2026

Accelerating Protein Engineering: Using Computer Modeling To Identify Beneficial Interleukin-23 (Il-23) Mutations, Andrew S. Chadwell

OneUSF Undergraduate Research Conference

Interleukin-23 (IL-23) regulates inflammation, yet its overproduction, driven by genetics or overactive immune triggers, can lead to chronic inflammatory diseases like psoriasis. IL-23 consists of two subunits; an exclusive subunit, p19, and a second subunit, p40, that is shared with Interleukin-12. Driving selectivity of p19-p40 interactions promotes a shift in cytokine formation between IL-23 and IL-12. By integrating computational biology, protein engineering, and structural data from the RCSB Protein Data Bank (entry 4RGW), the research addressed structural challenges like unresolved regions in experimental structures and the difficulty of predicting beneficial mutations. Structural modeling using ColabFold, a prediction tool based on …


Annotation Of The Immunity Cassette In Ay Cluster Phage Lebruni, Kelis Brown, Mehalia Hoyte, Ella King, Bianca Kulcsar, Zayda Perez Jul 2026

Annotation Of The Immunity Cassette In Ay Cluster Phage Lebruni, Kelis Brown, Mehalia Hoyte, Ella King, Bianca Kulcsar, Zayda Perez

OneUSF Undergraduate Research Conference

Bacteriophages typically follow either a lytic or lysogenic life cycle, yet the genetic mechanisms controlling the decision in Arthrobacter phages remain poorly understood. In the well-studied phage Lambda, various proteins are found to regulate the control between lysogeny and lysis. Inspired by this model, this research project investigates whether LeBruni contains immunity genes and a defined immunity cassette. LeBruni genes were annotated and analyzed using bioinformatics tools such as NCBI Blast, HHPred, PhageDB, and Phamerator to predict functions of the gene products. The immunity cassette in LeBruni determined to span genes 39 – 54, with gene 39 encoding a tyrosine …


Strategies To Improve Car-T Efficacy: Preconditioning, Gene Knockouts, And Enhancing Infiltration, Safa A. Khan, Salvina Alexander, Duy Anh Khuc, Tumaris Jarkinova, Fatema-Zahra Vhora, Neha Kunka, Rebecca Detweiler Jul 2026

Strategies To Improve Car-T Efficacy: Preconditioning, Gene Knockouts, And Enhancing Infiltration, Safa A. Khan, Salvina Alexander, Duy Anh Khuc, Tumaris Jarkinova, Fatema-Zahra Vhora, Neha Kunka, Rebecca Detweiler

OneUSF Undergraduate Research Conference

Chimeric Antigen Receptor T-cell (CAR-T) therapy is a powerful form of immunotherapy that has shown success in treating blood cancers. CAR-T cells often face challenges that limit their overall effectiveness; hence, researchers are focusing on strategies that improve how well CAR-T cells survive, grow, and target cancer cells. This review was conducted to analyze how CAR-T cells are constructed, highlight the major barriers that limit CAR-T’s efficacy, and determine how to improve it through preconditioning, gene knockouts, and enhanced infiltration. Literature was found through the PubMed, Scopus, and Web of Science databases. The following key search terms and synonyms were …


Comparative Analysis Of Car-T Cell Therapy Across Cancer Subtypes: Influence Of Antigen Binding Properties On Efficacy And Safety, Isabella Ware, Nadia Rohani, Kai Peñalosa, Samia Khan, Selena Berhie, Sreehitha Sajja Jul 2026

Comparative Analysis Of Car-T Cell Therapy Across Cancer Subtypes: Influence Of Antigen Binding Properties On Efficacy And Safety, Isabella Ware, Nadia Rohani, Kai Peñalosa, Samia Khan, Selena Berhie, Sreehitha Sajja

OneUSF Undergraduate Research Conference

CAR-T cell therapy is a personalized immunotherapy that genetically engineers a patient’s own immune T-cells in a lab to recognize and attack specific cancer cells. CAR-T cell therapy has shown remarkable success in hematologic malignancies, where antigen expression is highly uniform. The research question that was addressed is “To what extent does antigen heterogeneity and downregulation in solid tumors reduce CAR-T cell cytotoxicity compared with the more uniform antigen expression seen in hematologic malignancies?” CAR-T cell cytotoxicity is measurably reduced in solid tumors due to the tumor’s capacity to alter antigen expression and downregulate CAR proteins whereas hematologic malignancies exhibit …


Reproductive Equity: A Comparative Chemical Analysis Of Emerging Male Contraception Technology, Grace Kim, Esmaralda Pilar-Lopez Jul 2026

Reproductive Equity: A Comparative Chemical Analysis Of Emerging Male Contraception Technology, Grace Kim, Esmaralda Pilar-Lopez

OneUSF Undergraduate Research Conference

Female oral contraceptives, although abundant in access and successful as contraceptives, pose significant risks to women’s health. Biosocial factors that discourage male contraceptive drugs include harmful hormonal changes and inconsistent efficacy. This research employs comparative analysis of three current methods on potential male contraceptive options, focusing on steroid chemistry, functional group modification, and bioavailability. Emerging male contraceptive drugs of interest include the non-hormonal retinoic acid (vitamin A) receptor to antagonize sperm production, blocking the sperm-specific 〖Ca〗^(+2)  ion channel, and a reversible “Chemical Plug” that limits sperm movement at the vas deferens. Through comparison, this research will use six references to …


How Has Western Biomedical Framing Of Type 2 Diabetes Shaped Prevention And Treatment In South Asian Populations?, Amrita Nayak, Sreehitha Sajja Jul 2026

How Has Western Biomedical Framing Of Type 2 Diabetes Shaped Prevention And Treatment In South Asian Populations?, Amrita Nayak, Sreehitha Sajja

OneUSF Undergraduate Research Conference

This paper examines how Western biomedical framing of Type 2 diabetes (T2D) has shaped prevention and treatment strategies in South Asian populations, often with limited effectiveness. The dominant Western model emphasizes individual responsibility, standardized dietary guidelines, and generalized treatment protocols. While these approaches have proven useful in broader populations, they frequently fail to address the distinct biological, cultural, and structural realities that influence T2D risk among South Asians. A key limitation lies in the underrecognition of earlier metabolic risk. South Asian individuals tend to develop T2D at younger ages and lower body mass index (BMI) levels compared to European populations, …


It's In Your Dna: A Comprehensive Overview Of Forensic Genetic Genealogy And The Future Of Profiling Methods And Legal Implications, Selah A. Thompson Jul 2026

It's In Your Dna: A Comprehensive Overview Of Forensic Genetic Genealogy And The Future Of Profiling Methods And Legal Implications, Selah A. Thompson

OneUSF Undergraduate Research Conference

Forensic Genetic Genealogy (FGG) is a relatively modern and transformative technique within the field of forensics that allows for precise scientific identification of suspects or victims through DNA (Deoxyribonucleic Acid) analysis, primarily consisting of analyses of Short Tandem Repeats (STRs) and Single Nucleotide Polymorphisms (SNPs) found within samples of DNA. While FGG is quite new within the field, the applications for accurate, scientific-based analysis of crime scenes can help make an unsolvable case something that can be resolved, including some of the most famous cold cases of the past century. Current FGG technology provides incredibly valuable investigative leads, but current …


Determination Of The Degree Of Channeling Present Between Separate Catalytic Domains In Rat Peptidyl-Glycine Alpha-Amidating Monooxygenase, Chloe E. Jones, Tyler Holets, David J. Merkler Jul 2026

Determination Of The Degree Of Channeling Present Between Separate Catalytic Domains In Rat Peptidyl-Glycine Alpha-Amidating Monooxygenase, Chloe E. Jones, Tyler Holets, David J. Merkler

OneUSF Undergraduate Research Conference

Rat Peptidyl-Gly Alpha-Amidating Monooxygenase, or PAM, is the ortholog of the enzyme in humans solely responsible for amidating bioactive peptides to enable full biological function. The enzyme is composed of two catalytic domains held together by a flexible linker. The first domain is the copper-containing peptidylglycine α-hydroxylating monooxygenase, or PHM, which α-hydroxylates the peptidyl-glycine substrates. The second domain is the zinc-containing peptidyl-α- hydroxyglycine α-amidating lyase, or PAL, which produces glyoxylate and the amidated peptide final product. In part due to the flexible linker between the domains, the mechanism of substrate transfer between PHM and PAL is poorly characterized. Channeling, or …


Exploring Stem Faculty Perceptions On The Barriers Of Community Engaged Learning, Chandni M. Rattansingh Jul 2026

Exploring Stem Faculty Perceptions On The Barriers Of Community Engaged Learning, Chandni M. Rattansingh

OneUSF Undergraduate Research Conference

Calls to transform STEM education increasingly emphasize student-centered practices that move beyond passive lectures toward meaningful learning, preparing the future STEM workforce for complex, science-driven challenges. Community Engaged Learning (CEL) represents one such approach. While prior CEL research has largely focused on student outcomes, STEM faculty perceptions, especially regarding motivations, benefits, and barriers, remain understudied, despite faculty being central to CEL design and sustainability. This study investigates STEM faculty perceptions of the barriers to implementing CEL. We conducted 5 focus groups, each varying from 3-6 participants, intentionally separating adopters and non-adopters. Participants were STEM faculty from research-intensive universities holding the …


Optimization Of Antibiotic Selection Conditions In Human T-Cell Lines To Study Mechanisms Of Resistance To Bi-Specific Antibody Therapy In Multiple Myeloma, Raphael Gabra Jul 2026

Optimization Of Antibiotic Selection Conditions In Human T-Cell Lines To Study Mechanisms Of Resistance To Bi-Specific Antibody Therapy In Multiple Myeloma, Raphael Gabra

OneUSF Undergraduate Research Conference

Multiple myeloma is a malignancy of plasma cells for which emerging therapies increasingly target B-cell maturation antigen (BCMA). Many experimental approaches used to investigate therapeutic resistance rely on genetically modified cell populations that must be maintained through antibiotic selection to ensure stable expression of introduced constructs. However, antibiotic sensitivity varies across cell lines and drug types, and improper dosing can compromise experimental reproducibility by allowing unmodified cells to persist or inducing excessive cytotoxic stress. This study aimed to define efficient and practical selection conditions for two commonly used antibiotics, G418 and puromycin, in Jurkat and TALL-104 human T-cell lines. Cells …