Digital Commons Network^™

Cancer And Infection, Kathleen Hope Plummer

USF Tampa Graduate Theses and Dissertations

E. coli is the most frequently isolated Gram negative pathogen from bacteremia in cancer patients and is repeatedly recovered from many other extraintestinal illnesses. These infections are commonly endogenous in nature and interfere with the treatment of cancer resulting in increased healthcare costs, morbidity, and mortality rates. Cancer and the treatments related to cancer cause alterations in the microbiome of the gut and other organs. Despite this point, there is a serious lack of knowledge about the genetic types of E. coli infecting cancer patients. This gap results in vague prevention strategies and limited treatment options for cancer patients. Multi …

Manipulating The Tumor Microenvironment For Therapeutic Benefit, Kate M. Bailey

USF Tampa Graduate Theses and Dissertations

The physical tumor microenvironment contributes significantly to carcinogenesis, cancer progression and metastatic dissemination. Two main components of the tumor microenvironment, hypoxia and acidosis, are present in nearly every solid tumor and act as powerful selection forces against the tumor. Hypoxia and acidosis promote tumor heterogeneity and contribute to chemotherapy and radiotherapy resistance. This dissertation interrogates methods to target the tumor microenvironment including two novel studies describing mechanisms of buffer therapy resistance and targeting tumor hypoxia with vasodilators to enhance the efficacy of a hypoxia activated prodrug, TH-302.

In the first study, mechanisms of buffer therapy resistance were identified and detailed. …

Testing The Correlation Between Response Latency, Derivation, And Complexity, Jeffrey Ryan Oliver

USF Tampa Graduate Theses and Dissertations

This study investigates the constructs of Derivation and Complexity and how they relate to latency. Derivation and Complexity are theoretical constructs that have been posited as two of the main factors in differences in latency to responding in implicit measures such as the Implicit Relational Assessment Procedure (IRAP) and the Implicit Association Task (IAT). This study trained participants to relate two groups of novel stimuli in a linear fashion and then tested their latency to responding to derived relations (relations based on previously trained relations, but not directly trained themselves). The study then analyzed participant's latency to responding after dividing …

Applying Modeled Hemi-Ellipsoids To The Study Of Pressure Distribution In Normal And Paraplegic Seated Subjects, Alicia Billington

USF Tampa Graduate Theses and Dissertations

The three goals of this research were to investigate how normal subjects move while seated, how paraplegic patients move while seated, and whether seated movements can be modeled using a hemi-ellipsoid shape. Pressure readings were recorded at 11 Hz using a 36 by 36 sensor pressure map by XSENSOR. Subjects were instructed to move or perform pressure relief as they normally would while seated. Analysis was performed using Microsoft Excel with Solver and Matrix.xla add-ins and automated with VBA code. Major movements and time intervals between movements were calculated by locating the area of maximum pressure on each hemi-buttock for …

Method Of Treatment Of Cancer Using Guanosine 3′, 5′ Cyclic Monophosphate (Cyclic Gmp), David L. Vesely

USF Patents

A method of treating cancer through use of guanosine 3′,5′-cyclic monophosphate (cyclic GMP). Cyclic GMP decreases the number of human breast cancer and prostate adenocarcinoma as well as small-cell and squamous lung cells in culture by 30% (1 μM), 84% (1 mM), 31% (1 μM), and 30% (1 μM), respectively. Cyclic GMP decreases DNA synthesis in human pancreatic, breast, and prostate adenocarcinomas as well as small-cell and squamous cell carcinomas of the lung at its 1 μM concentration by 51%, 54%, 56%, 50% and 52%, respectively. Cyclic GMP when infused for one week decreases the tumor volume of human pancreatic …

Early Developmental Impacts On Male Traits And Female Preference In Zebra Finches (Taeniopygia Guttata), Martyna Boruta

USF Tampa Graduate Theses and Dissertations

Some male sexually selected traits are sensitive to stressors early in life and provide females with information to discriminate among males with different developmental experiences. Moreover, female early life experiences could also impact which males they choose. Females might either choose honest traits indicative of male quality, no matter their own experiences, or they might choose mates to match or compensate for their own experiences. To determine how developmental stressors alter male sexually-selected traits and female preference thereof, I exposed zebra finches (Taeniopygia guttata, ZEFI) to i) lipopolysaccharide (LPS), an immunogenic, Gram-negative bacterial component, ii) corticosterone (CORT), an avian stress …

Environment, Rights, And Waste In Bolivia: Addressing Water And Sanitation Processes For Improved Infrastructure, Maryann R. Cairns

USF Tampa Graduate Theses and Dissertations

Water and sanitation (WatSan) development projects impact both natural systems and societal structures where they are placed. A complex process of development, including inter-governmental policies, aid agencies, personal relationships, and community politics enhance and constrain the efficacy of these projects. This study presents the many ways in which the WatSan development process has unintended and unexpected returns for certain community groups. Using a political ecology framework, I look at power structures, perceived and projected environmental impacts, multiple stakeholders, and individual discourses to critique how the right to water and sanitation is implemented in a specific community context. This project advances …

The Weekly Challenger, June 19, 2014, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The June 19, 2014, issue of The Weekly Challenger.

Inactivation Of Ascaris In Double-Vault Urine-Diverting Composting Latrines In Panama: Methods And Environmental Health Engineering Field Applications, Daragh A. Gibson

USF Tampa Graduate Theses and Dissertations

The United Nations Millennium Development Goals have prioritized improving access to sanitation, but unfortunately about a third of the global population is still without an improved sanitation source and one billion still practice open defecation. Lack of access to adequate and safe sanitation means the proliferation of dangerous pathogens in the environment, especially soil-transmitted helminths (STHs). In the Bocas del Toro Province of Panama (and similar locations in the world), composting latrines have been built in many of the indigenous communities in the area. They are a form of dry or ecological sanitation and are designed to produce an end …

Targeting Cancer Metabolism With Ketosis And Hyperbaric Oxygen, Angela M. Poff

USF Tampa Graduate Theses and Dissertations

Cancer cells exhibit an abnormal metabolic phenotype characterized by glycolysis and lactate fermentation in the presence of oxygen, a phenomenon known as the Warburg effect. This dysregulated metabolism plays an important role in every aspect of cancer progression, from tumorigenesis to invasion and metastasis. The Warburg effect is a common phenotype shared by most, if not all, cancer types. It is especially prominent in metastatic tumors, which are notoriously resistant to treatment and responsible for the majority of cancer-related deaths. Thus, metabolic therapies which target the Warburg effect could offer novel therapeutic options for most cancer patients, including those with …

The Rhetoric Of Corporate Identity: Corporate Social Responsibility, Creating Shared Value, And Globalization, Carolyn Day

USF Tampa Graduate Theses and Dissertations

In today's global political and media climate, the stakes are high for corporations, local or otherwise, to create and maintain an `ethical' perception of not only their daily business activities and how they can benefit society or protect the environment, but also their enduring characteristics or `corporate identity' (Conrad, 2011) for numerous, sometimes conflicting stakeholder audiences (Cheney, 1983). This dissertation examines how such forms of `socially responsible' corporate identities are created and maintained through the use of persuasive language. In particular it examines the role and implications of rhetoric within the contexts of Corporate Social Responsibility (CSR), as well as …

Acculturation, Self-Efficacy And Breastfeeding Behavior In A Sample Of Hispanic Women, Ivonne F. Hernandez

USF Tampa Graduate Theses and Dissertations

Breastfeeding confers immunological, physiological and psychological benefits for the infant and mother as well as social and economic benefits to the nation. The United States Department of Health and Human Servcies (HHS), Healthy People 2020 has established national objectives for the initiation and duration of breastfeeding at 82% initiation, 61% at six months and 34% at one year. In addition, they have set goals for exclusive breastfeeding at 3 months to be 46% and 25% at 6 months of infant's age. Currently breastfeeding initiation is at the highest recorded level of 76.9%, yet significant disparities exist (CDC, 2012). The purpose …

Informing, Entertaining And Persuading: Health Communication At The Amazing You, David Haldane Lee

USF Tampa Graduate Theses and Dissertations

This is a study of the communication environment at The Amazing You, an exhibition about health and wellness with over 400 different exhibits at the Tampa Museum of Science and Industry (MOSI). The purpose of this study is to describe a multi-media, multi-vocal health communication environment which incorporates forms of intervention from various medical communities of practice into a narrative about human life stages. Describing communication at a science center as circular, complex and multi-directional allows for notions of feedback to be considered in an otherwise unilinear and unidirectional process from message to receiver. This research is about science center …

Agenda And Reports, Juvenile Welfare Board, May 8, 2014, Juvenile Welfare Board Of Pinellas County

Juvenile Welfare Board Agendas, Minutes, and Historical Audits

Agenda for the May 8, 2014, meeting of the Juvenile Welfare Board. Also included are previous meetings' minutes and documents to review before the meeting.

Commencement Convocation Program, Usf, Graduate, May 3, 2014, University Of South Florida

USF Graduation and Convocation Programs

Presidential Management Fellowship - Terrill Curtis; Fulbright U.S. Student Program - Trina Halfhide and Lauren Shumate

Craniometric Ancestry Proportions Among Groups Considered Hispanic: Genetic Biological Variation, Sex-Biased Asymmetry, And Forensic Applications, Meredith L. Tise

USF Tampa Graduate Theses and Dissertations

Today, groups considered Hispanic in the United States consist of populations whose complex genetic structures reflect intermixed diverse groups of people who came in contact during Spanish colonization in Latin America. After coming in contact and wiping out most of the Native Americans who occupied North and Latin America, the Spanish also introduced West African individuals for labor to begin developing crops to be shipped back to Europe, resulting in the Trans-Atlantic African slave trade. These migration events and differential gene flow among males and females that occurred throughout Latin America have led to populations that have been genetically transformed …

(−)-Epigallocatechin Gallate Derivatives For Inhibiting Proteasome, Tak-Hang Chan, Wai-Har Lam, Larry Ming-Cheung Chow, Qing Ping Dou, Deborah Joyce Kuhn, Aslamuzzaman Kazi, Sheng Biao Wan, Kristin R. Landis-Piwowar

USF Patents

A method of reducing tumor cell growth, the method including administering an effective amount of a compound having the formula:

Regeneration Rates Of The Brittle Star Ophiocoma Echinata Under Conditions Of Near-Future Ocean Acidification And Temperature, Steven E. Bruzek

USF St. Petersburg campus Honors Program Theses (Undergraduate)

Ocean acidification is the result of uptake of atmospheric CO2 in the oceans. Anthropogenic CO2 emissions have increased rapidly since the start of the Industrial Revolution. Along with an increase in acidity, the ocean’s average temperature is rising from global warming. This study investigates the near-future (year 2100) effects of acidification and temperature on regeneration rates of the brittle star Ophiocoma echinata. Using HCl to induce acidification, regeneration rates for near-future conditions (pH 7.8 and temperature 30°C) did not decrease significantly from present conditions. Regeneration increased significantly with an increase in temperature alone, suggesting a complex interaction between temperature and …

Growing Children: The Relationship Between Food Insecurity And Child Growth And Development., Ernesto Ruiz

USF Tampa Graduate Theses and Dissertations

This dissertation examined the relationship between food security status and cultural congruence and indicators of child growth and development in a rural mountain town in Costa Rica. Results show that children from food secure households are significantly shorter and shorter-legged than their food insecure counterparts. It is theorized that these findings correspond to low quality diets associated with increasing commodification of food systems in rural Costa Rica. Identity-based mechanisms are discussed as potential factors contributing to the increasing commodification of life through the encroachment of the global market economy.

Agenda And Reports, Finance Committee Meeting, Juvenile Welfare Board, April 22, 2014, Juvenile Welfare Board Of Pinellas County

Juvenile Welfare Board Agendas, Minutes, and Historical Audits

Agenda for the April 22, 2014, meeting of the Finance Committee of the Juvenile Welfare Board. Also included are previous meetings' minutes and documents to review before the meeting.

Harbor Notes, April 11, 2014, Jessica Blais

Harbor Notes

The April 11, 2014, issue of Harbor Notes.

Host-Parasite Interactions In An Invasive Songbird, Courtney A.C. Coon

USF Tampa Graduate Theses and Dissertations

Introduced species are the greatest threat to biodiversity after habitat loss. Understanding the processes that permit organisms to become successful invaders may provide opportunities to prevent or limit their dispersal and establishment and thereby alleviate some of their harmful effects. The goal of my dissertation research has been to investigate whether invasive species have distinctive interactions with parasites, and some of the mechanisms that may underlie that variation. I used one of the world's most successful vertebrate invaders as a case study: the house sparrow (Passer domesticus; Introduction).

Previous research in the house sparrow suggested that loss of …

Crow's Nest, April 7, 2014, Crow's Nest Staff

Crow's Nest

The April 7, 2014, issue of the Crow's Nest.

Multisensory Integration And Behavioral Plasticity In Sharks From Different Ecological Niches, Jayne M. Gardiner, Jelle Atema, Robert E. Hueter, Philip J. Motta

Integrative Biology Faculty and Staff Publications

The underwater sensory world and the sensory systems of aquatic animals have become better understood in recent decades, but typically have been studied one sense at a time. A comprehensive analysis of multisensory interactions during complex behavioral tasks has remained a subject of discussion without experimental evidence. We set out to generate a general model of multisensory information extraction by aquatic animals. For our model we chose to analyze the hierarchical, integrative, and sometimes alternate use of various sensory systems during the feeding sequence in three species of sharks that differ in sensory anatomy and behavioral ecology. By blocking senses …

Ang 6469 Anthropology Of Food, Roberta Baer

Service-Learning Syllabi

No abstract provided.

Monitoring Powdery Mildew Of Winter Wheat By Using Moderate Resolution Multi-Temporal Satellite Imagery, Jingcheng Zhang, Ruiliang Pu, Lin Yuan, Jihua Wang, Wenjiang Huang, Guijun Yang

School of Geosciences Faculty and Staff Publications

Powdery mildew is one of the most serious diseases that have a significant impact on the production of winter wheat. As an effective alternative to traditional sampling methods, remote sensing can be a useful tool in disease detection. This study attempted to use multi-temporal moderate resolution satellite-based data of surface reflectances in blue (B), green (G), red (R) and near infrared (NIR) bands from HJ-CCD (CCD sensor on Huanjing satellite) to monitor disease at a regional scale. In a suburban area in Beijing, China, an extensive field campaign for disease intensity survey was conducted at key growth stages of winter …

Exploring The Energy Link Between Emotion Regulation At Work And Health Behaviors, Ryan Christopher Johnson

USF Tampa Graduate Theses and Dissertations

The present study explores the process through which the regulation of emotions at work, also known as emotional labor, depletes self-regulatory resources, specifically energy, and distally impacts health behaviors in the form of less physical activity and more unhealthy eating. Differences in relationships between two forms of emotional labor, surface acting and deep acting, as well as differences between psychological and physical energy depletion, are explored. Additionally, the roles of trait mindfulness and future temporal focus are examined as between-individual differences moderating the proposed relationships.

Multi-level analysis of daily diary data collected from participants (N = 108 participants) over ten …

Obesity And Dining Out: An Exploration Of Dietary Trends In Urban Malaysia, Sylvia S. Lim

USF Tampa Graduate Theses and Dissertations

Economic growth has spurred rapid urbanization in Malaysia and triggered changes in diet, lifestyle, and disease trends. National studies show that a third of Malaysia's population is overweight/obese while household expenditures on dining out grow. In metropolitan Kuala Lumpur (KL), residents navigate concepts of nutrition, body weight, and health as they dine out. Using the biocultural framework, this study examined links between body weight, diet, income, street food consumption, and nutritional knowledge through the perspectives of consumers and vendors. Altogether, 77 participants were recruited for this three-phase research. In the first phase, a survey was administered to 60 participants recruited …

Religiosity, Spirituality, And Depressive Symptoms In Older Adults In An Active Living Community, Monica D'Adrianne Solomon

USF Tampa Graduate Theses and Dissertations

The population of older adults in the United States is steadily rising. The Centers for Disease Control and Prevention (CDC) recently released a call to reduce mental distress in older adults. Research shows that mental distress is associated with depressive symptoms, which are significantly related to many chronic medical conditions, functional impairment, suicide, and all-cause mortality. Depression is a major public health concern. There is an interest in gerontology research on the buffering role of engagement against depressive symptoms such as volunteering, social activities, and religion. Certain religious beliefs and behaviors contribute to maintaining or improving mental health and research …

The Hypertrophic Effects Of Practical Vascular Blood Flow Restriction Training, John Francis O'Halloran

USF Tampa Graduate Theses and Dissertations

Practical blood flow restriction training is a new training technique that has the potential to increase muscular hypertrophy and muscular strength while allowing practitioners to train with lighter loads (20-30% of 1-RM). Through the use of elastic knee wraps, the limbs can be restricted using a perceived pressure scale. The comparison of practical blood flow resistance training with traditional, non-blood flow restricted resistance training and its effects on muscular hypertrophy and strength has not been investigated.

Twenty-one resistance-trained males participated in a 4-week training program and were randomly assigned to one of two groups: Practical BFR training (BFR; n = …