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Nox2 Activity Is Required In Obesity-Mediated Alteration Of Bone Remodeling, Md Mizanur Rahman, Amina El Jamali, Ganesh V. Halade, Allal Ouhtit, Haissam Abou-Saleh, Gianfranco Pintus Jan 2018

Nox2 Activity Is Required In Obesity-Mediated Alteration Of Bone Remodeling, Md Mizanur Rahman, Amina El Jamali, Ganesh V. Halade, Allal Ouhtit, Haissam Abou-Saleh, Gianfranco Pintus

Internal Medicine Faculty Publications

Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. Nox2 is one of the predominant Nox enzymes expressed in the bone marrow microenvironment and is a major source of ROS generation during inflammatory processes. It is also well recognized that a high-fat diet (HFD) induces obesity, which negatively impacts bone remodeling. In this work, we investigated the effect of Nox2 loss of function on obesity-mediated alteration of bone remodeling using wild-type (WT) and Nox2-knockout (KO) mice fed with a standard lab chow diet …


Changing Patterns Of Hiv-Tb Coinfection Among Patients In A Public Health Department Ambulatory Care Setting: A 5-Year Experience From A Us Metropolitan Area, Anteneh Addisu, Sadaf Aslam, Douglas Holt, Sally Alrabaa, Beata Casanas Jan 2018

Changing Patterns Of Hiv-Tb Coinfection Among Patients In A Public Health Department Ambulatory Care Setting: A 5-Year Experience From A Us Metropolitan Area, Anteneh Addisu, Sadaf Aslam, Douglas Holt, Sally Alrabaa, Beata Casanas

Internal Medicine Faculty Publications

Background: HIV–TB coinfection leads to a complex set of synergistic interactions in the epidemiology, risk of acquisition, pathogenesis and prognosis of both infections. In the United States, the prevalence of HIV-TB coinfection has been around 6% for the past several years. We present here a 5-year experience at a public health department ambulatory care setting in Tampa, Florida, showing potentially changing patterns. Descriptive data and clinical aspect of coinfected patients is presented. Methods: A retrospective review of tuberculosis cases over the 5-year period ending December 2017 was performed. Those with HIV coinfection were included in the study. Clinical, microbiological and/or …


Annual Security And Fire Safety Report, 2018, University Of South Florida St. Petersburg. University Police Services. Jan 2018

Annual Security And Fire Safety Report, 2018, University Of South Florida St. Petersburg. University Police Services.

Crime Reports, Alerts, and Information

The annual security and fire safety report for the University of South Florida St. Petersburg's campus for 2018. This report satisfied requirements under the Clery Act.


Attitudes Of U.S. Hispanic And Non-Hispanic Women Toward Congenital Cmv Prevention Behaviors: A Cross Sectional Study, Rosemary Thackeray, Brianna M. Magnusson, Erica Bennion, Natalia N. Nielson, Ryan Bailey Jan 2018

Attitudes Of U.S. Hispanic And Non-Hispanic Women Toward Congenital Cmv Prevention Behaviors: A Cross Sectional Study, Rosemary Thackeray, Brianna M. Magnusson, Erica Bennion, Natalia N. Nielson, Ryan Bailey

Epidemiology and Biostatistics Faculty Publications

Background: Congenital cytomegalovirus (CMV) infection is the most common intrauterine infection. The only way to protect against congenital CMV infection is to practice CMV prevention behaviors. CMV seroprevalence rates are high in Hispanic women. It is unknown whether communication strategies should differ by ethnicity. The purpose of this study was to understand differences between U.S. Hispanic and non-Hispanic women’s attitudes toward CMV prevention behaviors and examine the relationship between perceived subjective norms and these attitudes.

Methods: This was a cross-sectional study using an online panel. Participants were U.S. women of childbearing age. The dependent variable was attitude toward practicing CMV …


Body Mass Index At Pediatric Leukemia Diagnosis And The Risks Of Relapse And Mortality: Findings From A Single Institution And Meta-Analysis, Ashleigh M. Saenz, Stacie Stapleton, Raquel G. Hernandez, Greg A. Hale, Neil A. Goldenberg, Skai W. Schwartz, Ernest K. Amankwah Jan 2018

Body Mass Index At Pediatric Leukemia Diagnosis And The Risks Of Relapse And Mortality: Findings From A Single Institution And Meta-Analysis, Ashleigh M. Saenz, Stacie Stapleton, Raquel G. Hernandez, Greg A. Hale, Neil A. Goldenberg, Skai W. Schwartz, Ernest K. Amankwah

Epidemiology and Biostatistics Faculty Publications

High body mass index (BMI) is associated with relapse of certain adult cancers, but limited knowledge exists on its association with pediatric leukemia relapse. We evaluated the association between overweight/obesity (BMI ≥ 85th percentile) at pediatric leukemia diagnosis and relapse or mortality. A meta-analysis combining our findings with those of previous studies was also performed. The study included 181 pediatric leukemia patients. Sporadic missing data were multiply imputed, and hazard ratios (HR) and 95% confidence intervals (95% CI) were calculated using Cox proportional hazard. Age- and sex-adjusted analysis for patients ≥10 years showed a trend towards increased risk of relapse …


Preparing To Launch The ‘Thinking Healthy Programme’ Perinatal Depression Intervention In Urban Lima, Peru: Experiences From The Field, B. S. Eappen, M. Aguilar, K. Ramos, C. Contreras, M. C. Prom, P. Scorza, B. Gelaye, M. Rondon, G. Raviola, Jerome T. Galea Jan 2018

Preparing To Launch The ‘Thinking Healthy Programme’ Perinatal Depression Intervention In Urban Lima, Peru: Experiences From The Field, B. S. Eappen, M. Aguilar, K. Ramos, C. Contreras, M. C. Prom, P. Scorza, B. Gelaye, M. Rondon, G. Raviola, Jerome T. Galea

Social Work Faculty Publications

Background. An estimated 19–25% of perinatal women in low- and middle-income countries are affected by depression which, untreated, is associated with multiple health problems for mothers and children. Nonetheless, few perinatal women have access to depression care. The Thinking Healthy Programme (THP), promoted by the World Health Organization (WHO), is an evidence-based, non-specialist delivered depression intervention that addresses this care gap. However, the WHO THP manual explains intervention delivery but not the antecedents to implementation. Here, we describe a principled, planned approach leading to the implementation of THP in Lima, Peru by the non-profit organization Socios En Salud with community …


Peroral Endoscopic Myotomy Is Effective And Safe In Non-Achalasia Esophageal Motility Disorders: An International Multicenter Study, Mouen A. Khashab, Pietro Familiari, Peter V. Draganov, Hanaa Dakour Aridi, Joo Young Cho, Michael Ujiki, Ricardo Rio Tinto, Hubert Louis, Pankaj N. Desai, Vic Velanovich, Eduardo Albéniz, Amyn Haji, Jeffrey Marks, Guido Costamagna, Jacques Devière, Yaseen Perbtani, Mason Hedberg, Fermin Estremera, Luis A. Martin Del Campo, Dennis Yang, Majidah Bukhari, Olaya Brewer, Omid Sanaei, Lea Fayad, Amol Agarwal, Vivek Kumbhari, Yen-I Chen Jan 2018

Peroral Endoscopic Myotomy Is Effective And Safe In Non-Achalasia Esophageal Motility Disorders: An International Multicenter Study, Mouen A. Khashab, Pietro Familiari, Peter V. Draganov, Hanaa Dakour Aridi, Joo Young Cho, Michael Ujiki, Ricardo Rio Tinto, Hubert Louis, Pankaj N. Desai, Vic Velanovich, Eduardo Albéniz, Amyn Haji, Jeffrey Marks, Guido Costamagna, Jacques Devière, Yaseen Perbtani, Mason Hedberg, Fermin Estremera, Luis A. Martin Del Campo, Dennis Yang, Majidah Bukhari, Olaya Brewer, Omid Sanaei, Lea Fayad, Amol Agarwal, Vivek Kumbhari, Yen-I Chen

Surgery Faculty Publications

Background and study aims: The efficacy of per oral endoscopic myotomy (POEM) in non-achalasia esophageal motility disorders such as esophagogastric junction outflow obstruction (EGJOO), diffuse esophageal spasm (DES), and jackhammer esophagus (JE) has not been well demonstrated. The aim of this international multicenter study was to assess clinical outcomes of POEM in patients with non-achalasia disorders, namely DES, JE, and EGJOO, in a large cohort of patients.

Patients and methods: This was a retrospective study at 11 centers. Consecutive patients who underwent POEM for EGJOO, DES, or JE between 1/2014 and 9/2016 were included. Rates of technical success (completion of …


Are Cancer Survivors Following The National Comprehensive Cancer Network Health Behavior Guidelines? An Assessment Of Patients Attending A Cancer Survivorship Clinic, Kelly A. Hyland, Jamie M. Jacobs, Inga T. Lennes, William F. Pirl, Elyse R. Park Jan 2018

Are Cancer Survivors Following The National Comprehensive Cancer Network Health Behavior Guidelines? An Assessment Of Patients Attending A Cancer Survivorship Clinic, Kelly A. Hyland, Jamie M. Jacobs, Inga T. Lennes, William F. Pirl, Elyse R. Park

Psychology Faculty Publications

Purpose: Engaging in positive health behaviors post-treatment is important for cancer survivors' health. However, little is known about whether survivors are practicing health promoting behaviors. We aimed to explore whether survivors are meeting the recent health behavior guidelines set forth by the National Comprehensive Cancer Network (NCCN) and to examine associations between health behaviors and distress. Methods: Sixty-six survivors completed a cross-sectional questionnaire assessing health behaviors prior to an initial appointment at a survivorship care clinic. Information about sociodemographic, clinical, and psychosocial variables and six health behavior recommendations, including physical activity, sunscreen use, tobacco use, alcohol consumption, weight …


He Narrowing Of Healing Practices: Andean Women And The State, Meghan O'Quinn Jan 2018

He Narrowing Of Healing Practices: Andean Women And The State, Meghan O'Quinn

USF St. Petersburg campus Honors Program Theses (Undergraduate)

In this paper, the multifaceted issues surrounding women's health in South America will be explored with a focus on the history of medical practices and how changing political and social tides affect the success of health services. Issues of sexism, racism, and religious influence have shaped how medicine is distributed and received. The interrelatedness of social issues and day-to-day medical care will be explored. The Centro de Salud in Pisac, as well as other programs, will be used as a case study in which the current challenges faced by women are examined. In addition, both grassroots and top-down efforts to …


The Politics Of Organic Food Consumption, Recycling And Solar Power Use, Ana Maria Quintero Jan 2018

The Politics Of Organic Food Consumption, Recycling And Solar Power Use, Ana Maria Quintero

USF St. Petersburg campus Honors Program Theses (Undergraduate)

The Republican and Democratic parties have long had different agendas, and I want to see if there is any evidence to suggest that Republicans are less supportive of environmental issues while Democrats are more supportive of environmental issues.1 There are many environmental issues, but I am interested in organic food consumption, recycling and solar energy. This research contains a literature review of these environmental subjects, a review of the two major political party platforms, an online survey of more than 100 USFSP students, and an analysis of the survey results. The most important finding is that there is no relationship …


Commencement Convocation Program, Usf, Graduate, December 9, 2017, University Of South Florida Dec 2017

Commencement Convocation Program, Usf, Graduate, December 9, 2017, University Of South Florida

USF Graduation and Convocation Programs

Honorary Doctor of Engineering and Nursing - Patricia Flatley-Brennan


Perceptual And Physiologic Analysis Of Dystussia In Amyotrophic Lateral Sclerosis, Stephanie Anne Watts Dec 2017

Perceptual And Physiologic Analysis Of Dystussia In Amyotrophic Lateral Sclerosis, Stephanie Anne Watts

USF Tampa Graduate Theses and Dissertations

Swallowing and cough are two vital functions that are reflexive in nature and are related to each other in terms of shared neural and anatomical space. When a disorder impacts normal and effective swallowing and/or cough, the consequences can be life-threatening. Evaluation and treatment of swallowing and cough disorders can fall under the scope of practice of the speech-language pathologist and speech-language pathologists often are leading professionals. Furthermore, much of the current research on swallowing and cough is spearheaded by speech-language pathologists often working with a multi-disciplinary team. The focus of this dissertation is on the clinical evaluation of cough …


Growing Trichoderma Asperellum, A Natural Fungicide, On Coffee Pulp And Husks, December 2017, Amber Devries, Georgia Van Tyne Dec 2017

Growing Trichoderma Asperellum, A Natural Fungicide, On Coffee Pulp And Husks, December 2017, Amber Devries, Georgia Van Tyne

Monteverde Institute: Tropical Ecology and Conservation

Coffee farms often rely on chemical fungicides to control fungal crop diseases such as ojo de gallo (Mycena citricolor) and red rust (Hemileia vastatrix). Trichoderma is a genus of fungus known to parasitize other fungi and it can be used to treat these crop diseases. Research has already proved that Trichoderma spp. can be cultivated on various organic substrates. Our goal was to help coffee farmers discover which coffee waste products could grow Trichoderma asperellum best. To do this, we collected three coffee by-products from Café de Monteverde: “young” coffee pulp, “old” coffee pulp, and coffee husks. We mixed these …


Differential Maternal Defense Behavior In Three Species Of Treehoppers (Hemiptera: Membracidae), December 2017, Mackenzie Kui Dec 2017

Differential Maternal Defense Behavior In Three Species Of Treehoppers (Hemiptera: Membracidae), December 2017, Mackenzie Kui

Monteverde Institute: Tropical Ecology and Conservation

Maternal care in the animal kingdom can vary immensely from species to species, but the reason for its ubiquity underlies an evolutionary impulse to pass on favorable genes to the next generation. In treehoppers, maternal care increases the rate of offspring survival through species-specific levels of protection from both predation and parasitism. To investigate the factors that influence maternal care, I introduced a variety of animate and inanimate stimuli to both brooding and non-brooding treehoppers in three species: Antianthe expansa, Alchisme grossa, and Umbonia crassicornis. By quantifying their responses as proxies for energy output, I concluded that maternal defense is …


Species Distribution Of The Rocky Intertidal Zone Organisms At La Islita In Cuajiniquil, Costa Rica, December 2017, John La Bonte Dec 2017

Species Distribution Of The Rocky Intertidal Zone Organisms At La Islita In Cuajiniquil, Costa Rica, December 2017, John La Bonte

Monteverde Institute: Tropical Ecology and Conservation

The rocky intertidal zone is an area of the seashore between the high and low tide marks with a hard substrate for organisms to move on. The organisms in this habitat face biotic and abiotic factors that determine their distribution and abundance through a biological mechanism called vertical zonation. I studied the rocky intertidal zone of La Islita near Cuajiniquil, Costa Rica in an effort to find the species that are present in this habitat and their relative abundance throughout the zone. I surveyed five transects that spanned the majority of La Islita to find where and in what abundance …


Diet Of Frugivorous Birds And Bats In Monteverde: Potential Seed Dispersal In Naturally Disrupted Areas, December 2017, Yibing Yu Dec 2017

Diet Of Frugivorous Birds And Bats In Monteverde: Potential Seed Dispersal In Naturally Disrupted Areas, December 2017, Yibing Yu

Monteverde Institute: Tropical Ecology and Conservation

After a natural disruption clears away the previous plant community, plants from the new vegetation succession will exploit the newly opened up spaces and start growing in this area. Seed dispersal by aerial animals is important in the new vegetation succession because it allows seeds from places relatively far away to access the area. In early October the storm Nate caused flash floods and landslildes, which disturbed many natural habitats in Monteverde. In this study I investigated plant species that naturally grow in disrupted areas by looking at what kind of seeds are dispersed by the frugivorous birds and bats …


Variability Of Mycorrhizal Colonization Amongst Varieties Of Coffea Arabica In Monteverde, Costa Rica, December 2017, Mckenzie Sime Dec 2017

Variability Of Mycorrhizal Colonization Amongst Varieties Of Coffea Arabica In Monteverde, Costa Rica, December 2017, Mckenzie Sime

Monteverde Institute: Tropical Ecology and Conservation

Mycorrhizae are a kind of fungus that forms symbiotic relationships with plants. They help plants deal with environmental stressors such as drought and disease. Almost all plants have this symbiosis with mycorrhizae, coffee being included in this group. Coffea arabica, a species of coffee, is grown in tropical regions and multiple varieties have been developed to increase the productivity of the plants. However, tropical regions, like Monteverde, Costa Rica where this study was conducted, are going to be some of the hardest areas hit by climate change. Plants are going to be depending more and more on their mycorrhizae as …


Medicinal Herbs And Mosquitoes: A Study Of Plant-Based Insect Repellents, December 2017, Miguel Alejandro Ochoa Dec 2017

Medicinal Herbs And Mosquitoes: A Study Of Plant-Based Insect Repellents, December 2017, Miguel Alejandro Ochoa

Monteverde Institute: Tropical Ecology and Conservation

Mosquito-borne illnesses present a great threat to human health, and result in millions of cases and hundreds of thousands of deaths annually. This study aimed to determine the effectiveness of extracted essential oils from three neotropical plants traditionally used in Costa Rican folk medicine as mosquito repellents. I extracted the essential oils of Siparuna decipiens (Monimiaceae), Gliricidia sepium (Fabaceae), and Neuroloena lobata (Asteraceae) via simple steam distillation. The extracted oils were then examined and compared to a negative control in the field on live volunteers, focusing on the mosquitoes in the Monteverde Zone, Puntarenas Province, Costa Rica. After a total …


Astaxanthin Attenuates Mptp Induced Neurotoxicity And Modulates Cognitive Function In Aged Mice, Beth Grimmig Dec 2017

Astaxanthin Attenuates Mptp Induced Neurotoxicity And Modulates Cognitive Function In Aged Mice, Beth Grimmig

USF Tampa Graduate Theses and Dissertations

Parkinson’s disease is the second common neurodegenerative disease and is most frequently diagnosed in individuals over 60. There are no available medications that can prevent or restore the loss of neurons that correspond to motor impairments in patients. Identifying novel therapeutic compounds that are capable of slowing and reversing the extensive neurodegeneration that occurs in PD remains an important goal of the field. While basic research has identified potential therapeutic agents, studies often use young model organisms to demonstrate efficacy of the target compound. This approach ignores the impact of the aged CNS on the disease process, and likely contributes …


Methane- And Dissolved Organic Carbon-Fueled Microbial Loop Supports A Tropical Subterranean Estuary Ecosystem, D. Brankovits, J. W. Pohlman, H. Niemann Nov 2017

Methane- And Dissolved Organic Carbon-Fueled Microbial Loop Supports A Tropical Subterranean Estuary Ecosystem, D. Brankovits, J. W. Pohlman, H. Niemann

KIP Articles

Subterranean estuaries extend inland into density-stratified coastal carbonate aquifers containing a surprising diversity of endemic animals (mostly crustaceans) within a highly oligotrophic habitat. How complex ecosystems (termed anchialine) thrive in this globally distributed, cryptic environment is poorly understood. Here, we demonstrate that a microbial loop shuttles methane and dissolved organic carbon (DOC) to higher trophic levels of the anchialine food web in the Yucatan Peninsula (Mexico). Methane and DOC production and consumption within the coastal groundwater correspond with a microbial community capable of methanotrophy, heterotrophy, and chemoautotrophy, based on characterization by 16S rRNA gene amplicon sequencing and respiratory quinone composition. …


Full Issue 46(3) Nov 2017

Full Issue 46(3)

International Journal of Speleology

No abstract provided.


Spatial-Temporal Distribution Of Mosquito Larval Hot Spots In Papoli, Uganda: A Community-Based Approach To Mosquito Control, Ryan E. Tokarz Nov 2017

Spatial-Temporal Distribution Of Mosquito Larval Hot Spots In Papoli, Uganda: A Community-Based Approach To Mosquito Control, Ryan E. Tokarz

USF Tampa Graduate Theses and Dissertations

Mosquito species of the Anopheles gambaie complex are the predominant vectors of malaria transmission throughout sub-Saharan Africa. These mosquitoes tend to be endophilic, as well as anthropophilic, making them prime candidates for disease transmission. Within the same region, related mosquito vectors play a significant role in the transmission of additional human and zoonotic diseases. Furthermore, mosquito nuisance biting is an immense issue that cannot be ignored in terms of its impact on African communities. Depending on the respective factors involved, mosquito control programs throughout the continent have attempted to tackle these issues in a multitude of ways. This research approached …


Using Green Messages To Cue Recycling Tendencies, Danielle Quichocho Nov 2017

Using Green Messages To Cue Recycling Tendencies, Danielle Quichocho

USF Tampa Graduate Theses and Dissertations

Recycling of common plastics is a practical way to limit the amount of waste that ends up in landfills, and eventually contributes to various forms of pollution. However, statistics indicate that it is not currently a normalized, prioritized behavior. A pilot study indicated that relying only on preexisting frameworks such as the Elaboration Likelihood Model to understand consumer perceptions simply does not encompass the scope of the topic. Consumer experiences with green messages, especially in the current climate of a saturated advertising market are incredibly complex. Understanding these experiences is also currently being impeded by inconsistencies in how researchers in …


Ecological Epigenetics Of Avian Range Expansions, Holly J. Kilvitis Nov 2017

Ecological Epigenetics Of Avian Range Expansions, Holly J. Kilvitis

USF Tampa Graduate Theses and Dissertations

In light of human-mediated environmental change, a fundamental goal for biologists is to determine which phenotypic characteristics enable some individuals, populations or species to be more adept at coping with such change, while rendering others more vulnerable. Studying ongoing range expansions provide a unique opportunity to address this question by allowing documentation of how novel environments shape phenotypic variation on ecological timescales. At range-edges, individuals are exposed to strong selective pressures and population genetic challenges (e.g. bottlenecks and/or founder effects), which make genetic adaptation difficult. Nevertheless, certain species, such as the house sparrow (Passer domesticus), seem to thrive in their …


Hidden: A Case Study On Human Trafficking In Costa Rica, Timothy Adam Golob Nov 2017

Hidden: A Case Study On Human Trafficking In Costa Rica, Timothy Adam Golob

USF Tampa Graduate Theses and Dissertations

This is a case study on human trafficking that was conducted on the small Central American country of Costa Rica via a mixed-methods approach which included document review, surveys, and interviews. It was selected due to Costa Rica’s history of fluctuation between Tier 2 and Tier 2 Watch List status on the Trafficking in Persons Report, issued by the U.S. Department of State, over the last ten years. This ranking average indicates that it is one of the worst performing Central American states in efforts to combat trafficking in persons. This finding breaks with Costa Rica’s traditional placement as one …


Agenda And Reports, Juvenile Welfare Board, November 9, 2017, Juvenile Welfare Board Of Pinellas County Nov 2017

Agenda And Reports, Juvenile Welfare Board, November 9, 2017, Juvenile Welfare Board Of Pinellas County

Juvenile Welfare Board Agendas, Minutes, and Historical Audits

Agenda for the November 9, 2017, meeting of the Juvenile Welfare Board. Also included are previous meeting minutes and reports to review before the meeting.


Adverse Childhood Experiences And Its Association With Cognitive Impairment In Non- Patient Older Population, Mohini D. Dutt Nov 2017

Adverse Childhood Experiences And Its Association With Cognitive Impairment In Non- Patient Older Population, Mohini D. Dutt

USF Tampa Graduate Theses and Dissertations

This study explores cognitive impairment and its correlation to early- life adverse experiences in non-patient population between the ages of 50 to 65. This developmental approach and observational study design explores cognition in pre-clinical Alzheimer’s disease (AD). Using a standardized neuropsychological instrument, the Montreal Cognitive Assessment (MoCA) and clinically administered questionnaire, the ACE (Adverse Childhood Experiences), I hypothesized that participants with high ACE scores will inversely have low MoCA scores.

My goal was to use a multiple linear regression model with 3 covariates and 1 predictor of interest (ACEs). At 80% power, a sample size of 40 was calculated as …


Method Of Treatment Of Cancer Using Guanosine 3', 5' Cyclic Monophosphate (Cyclic Gmp), David L. Vesely Nov 2017

Method Of Treatment Of Cancer Using Guanosine 3', 5' Cyclic Monophosphate (Cyclic Gmp), David L. Vesely

USF Patents

A method of treating cancer through use of guanosine 3',5'-cyclic monophosphate (cyclic GMP). Cyclic GMP decreases the number of human breast cancer and prostate adenocarcinoma as well as small-cell and squamous lung cells in culture by 30% (1 .mu.M), 84% (1 mM), 31% (1 .mu.M), and 30% (1 .mu.M), respectively. Cyclic GMP decreases DNA synthesis in human pancreatic, breast, and prostate adenocarcinomas as well as small-cell and squamous cell carcinomas of the lung at its 1 .mu.M concentration by 51%, 54%, 56%, 50% and 52%, respectively. Cyclic GMP when infused for one week decreases the tumor volume of human pancreatic …


How Did I Get Here? Testing The Translation Of The Morris Water Maze And The Influence Of Hemoglobin A1c On Spatial Navigation Performance, Colleen Pappas Nov 2017

How Did I Get Here? Testing The Translation Of The Morris Water Maze And The Influence Of Hemoglobin A1c On Spatial Navigation Performance, Colleen Pappas

USF Tampa Graduate Theses and Dissertations

Changes in cognitive status occur with aging and significant attention has been placed on developing interventions to possibly delay cognitive decline and identifying risk factors that exacerbate cognitive deficits. One issue that arises when studying interventions is that they do not always effectively translate from animal models to human subjects. When testing potentially modifiable risk factors related to cognitive impairment, more sensitive metrics could help in identifying targets for intervention at earlier time-points. Therefore, the aims of the current dissertation were twofold. The first study examined the ability to translate between species using a common behavioral paradigm, the Morris water …


Effect Of Exergaming On Physical Activity Of Adults With Intellectual Disabilities, Jennifer Dawn Vergara Nov 2017

Effect Of Exergaming On Physical Activity Of Adults With Intellectual Disabilities, Jennifer Dawn Vergara

USF Tampa Graduate Theses and Dissertations

Physical inactivity is the fourth leading risk factor related to death (World Health Organization, 2016a). Thus, the World Health Organization (2016a) suggests engaging in at least 150 min of physical activity (PA) throughout the week. Many individuals with intellectual disabilities (ID) engage in sedentary lifestyles that raise concern about their long-term health. The purpose of this study was to evaluate the effects of exergaming on PA and intensity when implemented with adults with ID. Four adult males diagnosed with ID were recruited. During the scheduled phase, percent occurrence of PA was variable across both conditions for each participant. During the …