Digital Commons Network^™

Biospeologica Bibliographia Publications 2011-1, Jean-Pierre Besson, Bernard Lebreton

KIP Articles

No abstract provided.

Crow's Nest, November 7, 2011, Crow's Nest Staff

Crow's Nest

The November 7, 2011, issue of the Crow's Nest.

Campus Board Meeting : 2011 : 11 : 03 : Supporting Documents, University Of South Florida St. Petersburg.

Campus Board Supporting Documents

No abstract provided.

Dengue Fever In Tegucigalpa, Honduras: Use Of The Explanatory Model In A Sample Of Urban Neighborhoods To Contextualize And Define Dengue Fever Among Community Participants, Jose Enrique Hasemann

USF Tampa Graduate Theses and Dissertations

This project elucidated the explanatory model of dengue fever held by members of urban communities in Tegucigalpa, Honduras. The study was conducted over a four-month period from May-August of 2011, and it was divided into two stages. The first stage of the project consisted of volunteer participation with dengue fever surveillance brigades in the three communities with the highest incidence of dengue fever during the beginning of 2011. This initial stage employed participant observation as its research method. The second stage was conducted in a different community within Tegucigalpa. The primary research methods employed during the second stage of the …

Flier, Xavier Cortada's Sequentia: Art And Science Together, October 20, 2011, University Of South Florida St. Petersburg. Nelson Poynter Memorial Library

Poynter Library Events

Flier for a talk and art exhibition by Xavier Cortada in honor of the 10th anniversary of sequencing the human genome. The talk was to be held at the University of South Florida St. Petersburg's Nelson Poynter Memorial Library.

Crow's Nest, October 10, 2011, Crow's Nest Staff

Crow's Nest

The October 10, 2011, issue of the Crow's Nest.

Generation Of Transgenic Human Soluble Amyloid Precursor Protein Alpha Expressing Mice, Jun Tan, William Nikolic, Huyan Hou

USF Patents

The present invention relates to a novel animal model for neurological degenerative diseases, especially autism, relating to overexpression of human secreted APP-alpha. This novel animal model exhibits several aspects of amyloidopathy. The present invention also relates to a method for producing the double transgenic animals, to cells and cell lines derived from these animals. Moreover, a method for the evaluation of the in vivo effects of a test compound on secreted APP-alpha expression and autism pathology in these animals is provided.

The Holistic Complementary Structure Of Western Bio-Medicine And Traditional Healing And Achieving Complete Health, Candace Gail Oubre

USF Tampa Graduate Theses and Dissertations

Achieving complete health requires a deep understanding of complementary cultural competency sensitivity between physician and patient. This may include but is not limited to access to preventative health care resources, access to health educational resources and access to cultural healing resources, for example, shamans, Ayurvedic physicians, and herbal healers. Advocates of cultural competency emphasize great importance on knowledge of the patients' cultural background; however, the transcendence of this knowledge can be explained further through complementary cultural competency sensitivity. This is when the cultures of the physician and patient complement each other in terms of understanding what is in the patients' …

Usf Women's Club Yearbook, 2011–2012, Usf Women's Club

USF Women’s Club Collection

Yearbook of the USF Women's Club. Inside is a list of past presidents, officers, committee chairmen, and members for 2011–2012. The booklet also includes a tribute to Grace Allen, interest groups, calendar of events, and a copy of the constitution and by-laws from the handbook.

Alcohol And Tobacco Use Among Monteverde Youth: A Preventative Approach, August 2011, Hannah Bose, Danielle Grams, Joshua Vollstaedt

Monteverde Institute: Culture, Community, and Health

This study investigates adolescent alcohol and tobacco consumption in the Monteverde zone of Costa Rica, addressing who engages in alcohol and tobacco use, what are the motivations to consume or not consume alcohol and tobacco, what protective and risk factors are acting on Monteverde youth, and what activities are desired by Monteverde youth.

Platinum Complexes For Targeted Drug Delivery, Heidi Kay

USF Patents

The subject invention concerns biotin-conjugated platinum complexes that exhibit direct and indirect (immunological) antitumor cell activity. The subject invention also concerns the biotin-platinum complexes of the invention that have another molecule, such as an antibody, a ligand, a receptor, etc., bound to the biotin moiety. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the invention can also be used to treat or prevent infection by a virus or a bacterial or parasitic organism in vivo or in vitro.

Platinum Complexes And Methods For Inhibiting Tumor Cell Proliferation, Heidi Kay, Jay W. Palmer, Joseph A. Stanko, Said M. Sebti

USF Patents

The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the invention can also be used to treat or prevent infection by a virus or a bacterial or parasitic organism in vivo or in vitro.

Characterization Of The Serologic Responses To Plasmodium Vivax Dbpii Variants Among Inhabitants Of Pursat Province, Cambodia, Samantha Jones Barnes

USF Tampa Graduate Theses and Dissertations

The Plasmodium vivax Duffy Binding Protein (DBP) is the ligand in the major pathway for P. vivax invasion of human reticulocytes, making it an appealing vaccine candidate. Region II of DBP (DBP-RII) is the minimal portion of the ligand that mediates recognition of the Duffy Antigen Receptor for Chemokines (DARC receptor) on the reticulocyte surface and constitutes the primary vaccine target. Analysis of natural variation in the coding sequences of DBP-RII revealed signature evidence for selective pressure driving variation in the residues of the putative receptor-binding site. We hypothesize that anti-DBP immunity in P. vivax infections is strain-specific and hindered …

Clonal Genotype Of Geomyces Destructans Among Bats With White Nose Syndrome, New York, Usa, Sunanda Rajkumar

KIP Articles

No abstract provided.

Nursing Students’ Attitudes Toward People With Mental Illness: Do They Change After Instruction And Clinical Exposure?, Rachel Morrison

Honors Thesis and Capstone Projects

People with mental illness are among the most stigmatized groups of patients in the healthcare setting (Putnam, 2008). Nurses comprise roughly 15.3 percent of the healthcare team (U.S. Bureau of Labor Statistics, 2010) and have frequent direct interactions with patients. As one of the larger groups of healthcare providers, nurses can potentially influence this stigma, either by contributing to the prevalent negative attitudes, or by confronting expressions of stigma. A requirement for licensure is to take a course in Mental Health. One of the goals of this course is to decrease stigma toward people with mental illness (American Association of …

The Knowledge, Attitudes, And Behaviors Of Gay, Lesbian, Bisexual And Transgender University Of South Florida (Usf) Students Concerning Human Papillomavirus (Hpv) And The Hpv Vaccine, Andrea E. Larson

Honors Thesis and Capstone Projects

Human papillomavirus (HPV) is one of the most common sexually transmitted diseases and can cause several types of cancer, including cervical and anal cancer. The lesbian, gay, bisexual, and transgender (LGBT) population is an often overlooked subgroup at risk for HPV. The purpose of this research was to describe LGBT college students‟ knowledge, attitudes, and behaviors pertaining to HPV and the HPV vaccine. An online survey consisting of 54 items was created and sent to members of an organization consisting primarily of LGBT students at the University of South Florida. A total of 155 students completed the survey. Several major …

Anti-Malarial Activity Exhibited By Florida Mangrove Endophytes, Jacqueline Lee Salm

Honors Thesis and Capstone Projects

Many organisms around the world including plants, marine organisms, and microbes release chemicals used for things such as pigment or defense against other organisms. These chemicals are known as secondary metabolites and have been found to exhibit promising activity against many infectious diseases and cancer. Natural products chemistry is the study of these secondary metabolites with one of the purposes to discover new small organic molecules for potential pharmaceutical use in the future. With parasitic diseases, such as malaria, prominent throughout the poorest regions of the world, there are great opportunities for discovering anti-malarial drugs from natural products. Approximately 250 …

Secondary Metabolites From Antarctic Marine Invertebrates And Their Potential As Drug Leads, Samantha Landolfa

Honors Thesis and Capstone Projects

The Antarctic region is of particular interest to natural products chemists because it remains relatively unexplored and possesses a wealth of unique biodiversity. Organisms that thrive in this region must produce different chemical defenses to survive in the harsh polar environment, making their secondary metabolites original and potentially useful as drugs for human disease. These compounds often have very complex structures, making their syntheses difficult and impractical. With this knowledge, five Antarctic marine invertebrates were extracted in search of their secondary metabolites. The chemical isolation studies were performed by macroorganism solvent extraction followed by chromatographic separation and purification of metabolites …

Barrier-Permeable Proxy Reporter Analysis, David Fries, Brian Gregson

USF Patents

Analysis of complex media (e.g.—blood and seawater) is difficult because the media are composed of particles of different sizes and chemical profiles. Disclosed is a method for the detection of a constituent in a medium that enhances the molecular selectivity of a detector by separating the detector from the medium by a membrane of specified permeability. Proxy reporters are employed to enhance particle specificity. The novel combination of the invention has application to chemical detection in a broad range of fields.

Calculus, Biology And Medicine: A Case Study In Quantitative Literacy For Science Students, Kim Rheinlander, Dorothy Wallace

Numeracy

This paper describes a course designed to enhance the numeracy of biology and pre-medical students. The course introduces students with the background of one semester of calculus to systems of nonlinear ordinary differential equations as they appear in the mathematical biology literature. Evaluation of the course showed increased enjoyment and confidence in doing mathematics, and an increased appreciation of the utility of mathematics to science. Students who complete this course are better able to read the research literature in mathematical biology and carry out research problems of their own.

Modeling And Surveillance Of Pandemic Influenza Outbreaks, Diana Prieto

USF Tampa Graduate Theses and Dissertations

Pandemic outbreaks are unpredictable as to their virus strain, transmissibility, and impact on our quality of life. Hence, the decision support models for mitigation of pandemic outbreaks must be user-friendly and operational, and also incorporate valid estimates of disease transmissibility and severity. This dissertation research is aimed at 1) reviewing the existing pandemic simulation models to identify their implementation gaps with regard to usability and operability, and suggesting research remedies, 2) increasing operability of simulation models by calibrating them via an epidemiological model that estimates infection probabilities using viral shedding profiles of concurrent pandemic and seasonal influenza, and 3) developing …

Broad Surveys Of Dna Viral Diversity Obtained Through Viral Metagenomics Of Mosquitoes, Terry Fei Fan Ng, Dana Willner, Yan Wei Lim, Robert Schmieder, Betty Chau, Christina Nilsson, Simon Anthony, Yijun Ruan, Forest Rohwer, Mya Breitbart

Marine Science Faculty Publications

Viruses are the most abundant and diverse genetic entities on Earth; however, broad surveys of viral diversity are hindered by the lack of a universal assay for viruses and the inability to sample a sufficient number of individual hosts. This study utilized vector-enabled metagenomics (VEM) to provide a snapshot of the diversity of DNA viruses present in three mosquito samples from San Diego, California. The majority of the sequences were novel, suggesting that the viral community in mosquitoes, as well as the animal and plant hosts they feed on, is highly diverse and largely uncharacterized. Each mosquito sample contained a …

Predictive And Reactive Distribution Of Vaccines And Antivirals During Cross-Regional Pandemic Outbreaks, Andrés Uribe-Sánchez, Alex Savachkin

Industrial and Management Systems Engineering Faculty Publications

As recently pointed out by the Institute of Medicine, the existing pandemic mitigation models lack the dynamic decision support capability. We develop a large-scale simulation-driven optimization model for generating dynamic predictive distribution of vaccines and antivirals over a network of regional pandemic outbreaks. The model incorporates measures of morbidity, mortality, and social distancing, translated into the cost of lost productivity and medical expenses. The performance of the strategy is compared to that of the reactive myopic policy, using a sample outbreak in Fla, USA, with an affected population of over four millions. The comparison is implemented at different levels of …

Laparoscopic Drainage Of A Hepatic Echinococcal Cyst: A Case Report, Steven B. Goldin, James J. L. Mateka, Michael J. Schnaus, Sujat Dahal

Surgery Faculty Publications

The Echinococcus granulosus tapeworm causes hepatic echinococcosis. It is endemic in the Mediterranean region, Middle East, and South America. Human infection is secondary to accidental consumption of ova in feces. Absorption through the bowel wall and entrance into the portal circulation leads to liver infection. This case involves a 34 y/o Moroccan male with an echinococcal liver cyst. His chief complaint was RUQ pain. The patient was treated with albendazole and praziquantel. His PMH and PSH was noncontributory. Patient was not on any other medications. ROS was otherwise unremarkable. The patient was AF VSS. He was tender to palpation in …

Decision Aid Models For Resource Sharing Strategies During Global Influenza Pandemics, Alfredo Santana Reynoso

USF Tampa Graduate Theses and Dissertations

Pandemic influenza outbreaks have historically entailed significant societal and economic disruptions. Today, our quality of life is threatened by our inadequate preparedness for the imminent pandemic. The key challenges we are facing stem from a significant uncertainty in virus epidemiology, limited response resources, inadequate international collaboration, and the lack of appropriate science-based decision support tools. The existing literature falls short of comprehensive models for global pandemic spread and mitigation which incorporate the heterogeneity of the world regions and realistic travel networks. In addition, there exist virtually no studies which quantify the impact of resource sharing strategies among multiple countries. This …

Tarnished Golden Years: Older Offenders With Mental Health Problems And Late Life First Time Offenders, Brianne Stanback

USF Tampa Graduate Theses and Dissertations

Older offenders (offenders 50 years and older) are a distinct groups within the U.S. correctional system. Studies 1 and 2 were intended to investigate mental health and stressors among jailed older offenders.

Study 1 examined the prevalence rates of mental health disorders and explored the relationship between mental health disorders and stressors. Participants 50 years and older (N=330) from the 2002 wave of the Survey of Inmates in Local Jails (SILJ) were studied via descriptive analysis, factor analysis, and a logistic regression to determine which variables were related to the probability of having a mental health problem. 65.8% of participants …

Development Of An Elisa For Eastern Equine Encephalitis Virus That Can Differentiate Infected From Vaccinated Horses, Andrea Bingham

USF Tampa Graduate Theses and Dissertations

Eastern Equine Encephalitis virus (EEEV) causes a fatal mosquito-borne virus that is vaccine preventable for horses. The conventional serological tests measure antibodies to the structural proteins of EEEV which are also found in the vaccine. This makes it difficult to differentiate infected and vaccinated animals (DIVA). Detection of antibodies to non-structural proteins (NSPs) is a theoretical strategy that would allow you to survey natural infections among vaccinated populations. This test would also allow for more accurate representations of the natural infection rate, vaccination rate, and help identify vaccine failures. The potential uses of the NSPs of Eastern Equine Encephalitis virus …

Natural Product Drug Discovery Against Tropical Diseases, Wai Sheung Ma

USF Tampa Graduate Theses and Dissertations

This dissertation describes the isolation of secondary metabolites from natural origins through a series of chromatographic techniques and spectrometric characterization in the effort of drug discovery. The isolated compounds obtained were used as drug leads against tropical diseases, namely malaria and leishmaniasis. While first chapter offers an introduction on the use of a natural product by itself as an effective therapeutic and its role on inspiring the discovery of new drugs, the later chapters will concentrate on isolation and characterization of bioactive natural products from an Antarctic sponge and mangrove endophytic fungi during the dissertation work.

The second chapter describes …

Understanding The Psychosocial Aspects Of Waterpipe Smoking Among College Students, Mary Pautler Martinasek

USF Tampa Graduate Theses and Dissertations

Waterpipe tobacco smoking has migrated from being a custom of some cultures to becoming a staple around college campuses. The social nature and flavored tobacco encourage initiation in this tobacco naïve age group.

The study was a sequential mixed method design, employing primary data collection and analysis of a random sample of university students who live on campus at a single university. The study involved observations (N=6), intercept interviews with smokers and nonsmokers (N=63), three focus groups (N=31), and an online survey (N=288).

Findings were centered on the constructs of the Theory of Reasoned Action by Ajzen and Fishbein (1975), …

The Role Of Hiv-1 Proteins In Alzheimer's Disease Pathology, Brian Nelson Giunta

USF Tampa Graduate Theses and Dissertations

Prevalence of HIV-associated cognitive impairment is rising, the worst form of which is HIV-associated dementia (HAD). The disease is fuiled by a chronic innate type pro-inflammatory response in the brain which is highly dependent upon the activation of microglia. We first created an in vitro model of HAD composed of cultured microglial cells synergistically activated by the addition of IFN-gamma and the HIV-1 coat glycoprotein, gp120. This activation, as measured by TNF-alpha and NO release, is synergistically attenuated through the alpha7nAChR and p44/42 MAPK system by pretreatment with nicotine, and the cholinesterase inhibitor, galantamine. As these medications have been FDA …