Digital Commons Network^™

Streptococcus Intermedius Bacteremia And Liver Abscess Following A Routine Dental Cleaning, Lachara V. Livingston, Elimarys Perez-Colon

Internal Medicine Faculty Publications

Streptococcus intermedius is a member of the Streptococcus anginosus group of bacteria. This group is part of the normal flora of the oropharynx, genitourinary, and gastrointestinal tracts; however, they have been known to cause a variety of purulent infections including meningitis, endocarditis, and abscesses, even in immunocompetent hosts. In particular, S. intermedius has been associated with the development of liver and brain abscesses. There have been several case reports of S. intermedius liver abscesses with active periodontal infection. To our knowledge, however, there has not been a case following a routine dental procedure. In fact, the development of liver abscesses …

Classification Of Epidemic Community-Acquired Methicillin-Resistant Staphylococcus Aureus By Anatomical Site Of Isolation, Jill C. Roberts

Environmental and Occupational Health Faculty Publications

Methicillin-resistant Staphylococcus aureus contributes significantly to cost, morbidity, and mortality due to infectious disease. We surveyed community-associated MRSA isolates to determine which strains were present within anatomical sites of interest. The most likely sources of MRSA among anatomic sites swabbed were wounds followed by the nasal cavity. The USA 300 MRSA strain was most commonly isolated among wound infections while nasal swabs largely yielded USA 100 MRSA. The frequency of isolation of USA 100 amongst community-associated strains is clinically significant as this strain is often correlated with invasive disease, exhibits broad antibiotic resistance, and has been considered to be hospital …

2014 Accountability Report Usf System, Usf

USF Accountability Reports

No abstract provided.

2014 Accountability Report Usf Tampa, Usf

USF Accountability Reports

No abstract provided.

Identification And Ss-Lactam Resistance In Aquatic Isolates Of Enterobacter Cloacae And Their Status In Microbiota Of Domica Cave In Slovak Karst (Slovakia), Barbora Gaalova, Alena Donauerova, Milan Seman, Helena Bujdakova

International Journal of Speleology

Domica Cave is located in the Slovak Karst National Park in southern Slovakia. Heterotrophic cultivable psychrophilic and mesophilic microbiota were confirmed to be prevalent in this cave. Escherichia coli was the most abundant bacterium, followed by Enterobacter species and Serrratia species. Enterobacter cloacae isolates belong to the group of faecal contaminants (coliforms) of concern in water. Their status in cave ecosystem is questionable, but we observed E. cloacae in water samples all years round suggesting an autochthonous origin. We were concerned with possible contamination of the cave water with resistant E. cloacae from animal farms located 2-3 km from the …

Speleomycological Research In Underground Osówka Complex In Sowie Mountains (Lower Silesia, Poland), Wojciech Pusz, Rafał Ogórek, Cecylia Miłowana Uklańska-Pusz, Paweł Zagożdżon

International Journal of Speleology

Osówka (Germ. Säuferhöhen), is one of the elements of the unfinished Nazi military complex called “Riese”. The total length of corridors of Osówka complex is about 1,700 m and its capacity amounts to 30,000 m³. As described geologically, Osówka is situated within the Sowie Mts. Massif which consists mostly of various gneisses with different structural characteristics, but with a constant mineral composition. The rock-forming minerals are feldspar (oligoclase), quartz, biotite and light micas, accesory minerals are garnet, sillimanite and dysten. Fine-grained shallow-sea deposits were probably a protolith of these rocks. The study aimed at first mycological evaluation of …

Diversity Of Cultivable Bacteria Involved In The Formation Of Macroscopic Microbial Colonies (Cave Silver) On The Walls Of A Cave In Slovenia, Blagajana Herzog Velikonja, Rok Tkavc, Lejla Pašić

International Journal of Speleology

Karstic caves often support white, yellow, grey or pink microbial colonies that are termed ‘cave silver’ by speleologists. Using various sample pre-treatments and culture media, a wide variety of bacteria associated with these colonies were recovered from a cave in Slovenia, Pajsarjeva jama. Decreasing the inoculum size resulted in significant increases in viable counts, while pre-treatments had the opposite effect with the exception of microwave irradiation. While all growth media yielded viable counts, the maximal counts were observed on a low-nutrient TWA medium.

Based on the 16S rRNA gene sequence of OTU representatives, the majority of the 80 isolates examined …

Genetic Adjuvants For Immunotherapy, Shyam S. Mohapatra, Mukesh Kumar

USF Patents

The present invention pertains to methods and pharmaceutical compositions for modulating an immune response. The method of the present invention involves administration of an effective amount of nucleic acid molecules encoding interleukin-12 (IL-12), interferon-gamma (IFN-γ), or a combination thereof, to a patient in need of such treatment. The pharmaceutical compositions of the invention contain nucleic acid molecules encoding IL-12 and/or IFN-γ and an operably-linked promoter sequence. In another aspect, the present invention concerns expression vectors containing a nucleotide sequence encoding IL-12 and IFN-γ, and an operably-linked promoter sequence. In another aspect, the present invention concerns cells genetically modified with a …

Methods For Inhibiting Tumor Cell Proliferation, James Turkson, Richard Jove, Jay Palmer, Heidi Kay, Hua Yu

USF Patents

The subject invention concerns methods for inhibition of STAT biological functions using platinum complexes.

Jak/Stat Inhibitors And Mapk/Erk Inhibitors For Rsv Infection, Shyam S. Mohapatra

USF Patents

The present invention concerns a method for treating or reducing the likelihood of developing a respiratory syncytial virus (RSV) infection in a subject by administering an effective amount of an inhibitor of the janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathway or the mitogen-activated kinase (MAPK)/extracellular signal-regulated kinase (ERK1/2) signaling pathway to the subject. Another aspect of the invention concerns a pharmaceutical composition that includes an inhibitor of JAK/STAT or MAPK/ERK signaling to the subject; and a pharmaceutically acceptable carrier. Another aspect of the invention concerns a method for identifying agents useful for treating or reducing the …

Factors Influencing Vaccination Decisions In African American Mothers Of Preschool Age Children, Chauntel Mckenzie Mcnair

USF Tampa Graduate Theses and Dissertations

Rates and coverage levels of immunizations of African-American children are reduced compared to other races. Few studies have identified factors that influence vaccination decisions of African-American mothers. This study assessed the mothers' vaccination decisions using a self-administered questionnaire and a screening instrument for determining health literacy. This instrument is called Rapid Estimate of Adult Literacy in Medicine (REALM). The sample was 92 African American mothers, recruited from a large metropolitan church in Jacksonville, Florida, who had at least one child under the age of seven. A cross-sectional research design was used to administer survey instruments to identify and interpret parental …

Mycological Study For A Management Plan Of A Neotropical Show Cave (Brazil), Erika Linzi Silva Taylor, Maria Aparecida De Resende Stoianoff, Rodrigo Lopes Ferreira

International Journal of Speleology

Caves are stable environments with characteristics favoring the development of microorganisms. The allocthonous input of organic matter and microbes into the warm Neotropical caves may favor the development of filamentous fungi, including pathogenic species. Histoplasma capsulatum is a pathogenic species commonly found in caves and associated with bat and bird guano. Many Brazilian caves have been historically visited due to scenic and religious tourism. The objective of this study was to perform a microbiology study for a management plan of a show cave in Brazil, focusing on the presence and distribution of pathogenic and opportunistic fungi in the cave. Statistics …

The Weekly Challenger, September 5, 2013, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The September 5, 2013, issue of The Weekly Challenger.

Skin Lesions In European Hibernating Bats Associated With Geomyces Destructans, The Etiologic Agent Of White-Nose Syndrome, Gudrun Wibbelt, Sébastien J. Puechmaille, Bernd Ohlendorf, Kristin Mühldorfer, Thijs Bosch, Tamás Görföl, Karsten Passior, Andreas Kurth, Daniel Lacremans, Frédéric Forget

KIP Articles

No abstract provided.

Acylsulfonamides And Processes For Producing The Same, Hong-Gang Wang, Roman Manetsch, Xiangdong Hu, Sameer Kulkarni, Jiazhi Sun

USF Patents

The present disclosure relates to acylsulfonamides and processes for their preparation. The processes involve a target-guided synthesis approach, whereby a thioacid and a sulfonyl azide are reacted in the presence of a biological target protein, a Bcl-2 family protein, to form the acylsulfonamide.

Characterizing The Syphilis Epidemic Among Men Who Have Sex With Men In Lima, Peru To Identify New Treatment And Control Strategies, Robert Deiss, Segundo R. Leon, Kelika A. Konda, Brandon Brown, Eddy R. Segura, Jerome T. Galea, Carlos F. Caceres, Jeffrey D. Klausner

Social Work Faculty Publications

Background: Syphilis is an important sexually transmitted infection (STI) with serious public health consequences. Among men who have sex with men (MSM) in Lima, the prevalence and incidence are extraordinarily high. Current syndromic approaches, however, fail to identify asymptomatic cases, and in settings where large proportions of individuals test positive again after treatment, it is frequently difficult to distinguish treatment failure from re-infection. Thus, new approaches are needed to improve treatment strategies and public health control efforts.

Methods/Design: Study participants will undergo baseline testing for syphilis infection along with a behavioral survey covering demographics, sexual behavior, drug and …

Atp-Bioluminescence Immunoassay, Daniel V. Lim, Dawn M. Hunter

USF Patents

Disclosed is a method and associated device for the rapid identification of viable bacterial contaminants in food products. The method detects viable microbes by using a combined ATP-bioluminescence immunoassay. Escherichia coli O157:H7 and Salmonella enterica serovar Typhimurium were selected as target organisms in various matrices including ground beef homogenate, apple juice, milk, and phosphate-buffered saline. Specific antibodies were immobilized on the surface of well plates in which the sample matrices were incubated. The plates were washed, and the wells were incubated with BacTiter-Glo reagent in Mueller-Hinton II broth. Bioluminescent output was measured with a luminometer and signal-to-noise ratios were calculated. …

Usf Women's Club Yearbook, 2013–2014, Usf Women's Club

USF Women’s Club Collection

Yearbook of the USF Women's Club. Inside is a list of past presidents, officers, committee chairmen, and members for 2013–2014. The booklet also includes a tribute to Grace Allen, interest groups, calendar of events, and a copy of the constitution and by-laws from the handbook.

Beyond The Storms: Strengthening Preparedness, Response, & Resilience In The 21st Century, Dane S. Egli

Journal of Strategic Security

Looking Beyond the Storms of major events and reactionary tendencies to prevent future disasters—and continuing to fix things—the author introduces a fresh assessment in the wake of Superstorm Sandy, the vexing challenge of domestic shootings, and a persistent nationwide drought. This paper offers a refreshing perspective on the need for transformational and innovative thinking on preparedness, response, and resilience, as well as disaster management. Against the backdrop of 9-11 terrorist attacks and natural disasters such as hurricanes Katrina, Irene, and Sandy, this paper, highlights that we—as homeland security planners and policymakers—must look beyond the immediate demands of grant proposals and …

Antibiotic-Bound Poly(Caprolactone) Polymer, Edward Turos, Michelle Leslie

USF Patents

This invention is the design and synthesis of a caprolactone monomer which bears a pendant protected carboxyl group. This monomer has been copolymerized with caprolactone in varying ratios. After polymerization, the protecting group can be removed and an antibiotic can be attached as a new pendant group. The bioactivity of the antibiotic-bound poly(caprolactone) polymer is described.

Platinum Complexes And Methods For Inhibiting Tumor Cell Proliferation, Heidi Kay, Jay W. Palmer, Joseph A. Stanko, Said M. Sebti

USF Patents

The subject invention concerns platinum complexes that exhibit antitumor cell and/or antiparasitic activity. The subject invention also concerns the use of platinum complexes of the invention to treat oncological and inflammatory disorders. The platinum complexes of the invention can also be used to treat or prevent infection by a virus or a bacterial or parasitic organism in vivo or in vitro.

Novel Sars-Like Betacoronaviruses In Bats, China, 2011, Li Yang, Zhiqiang Wu, Xianwen Ren

KIP Articles

To clarify the evolutionary relationships among betavoronaviruses that infect bats, we analyzed samples collected during 2010–2011 from 14 insectivorous bat species in China. We identified complete genomes of 2 novel betacoronaviruses in Rhinolophus pusillus and Chaerephon plicata bats, which showed close genetic relationships with severe acute respiratory syndrome coronaviruses.

Effective Treatment Of Tumors And Cancer With Triciribine And Related Compounds, Jin Q. Cheng, Said M. Sebti

USF Patents

The inventors have determined, contrary to the prior art and experience, how to successfully use triciribine to treat tumors and cancer by one or a combination of (i) administering triciribine only to patients which according to a diagnostic test described below, exhibit enhanced sensitivity to the drug; (ii) use of a described dosage level that minimizes the toxicity of the drug but yet still exhibits efficacy; or (iii) use of a described dosage regimen that minimizes the toxicity of the drug.

The Problem, One Solution, And The Future : An Investigation Of Current And Future Insect Pest Management, Tanjim Hossain

USF St. Petersburg campus Honors Program Theses (Undergraduate)

No abstract provided.

Journal Of Cave And Karst Studies, Volume 75, No. 1, April 2013, Malcolm S. Field

KIP Articles

Contents: Evaluation of Strategies for the Decontamination of Equipment for Geomyces Destructans, the Causative Agent of White-Nose Syndrome (WNS) -- Ostracod Assemblages in the Frasassi Caves and Adjacent Sulfidic Spring and Sentino River in the Northeastern Apennines of Italy -- Electric Tomography Applies to the Detection of Subsurface Cavities -- Temporal Variability of Cave-Air CO2 in Central Texas -- High Resolution Seismic Reflection Methods to Detect Near Surface Tuff-Cavities: A Case Study in the Neapolitan Area, Italy -- Chaetaspis Attenuatus, A New Species of Cavernicolous Milliped from Arkansas (Diplopoda: Polydesmida: Macrosternodesmidae) -- Caecidotea Insula, A New Species …

Hibernating Little Brown Myotis (Myotis Lucifugus) Show Variable Immunological Responses To White-Nose Syndrome, Marianne S. Moore, Jonathan D. Reichard, Timothy D. Murtha, Morgan L. Nabhan, Rachel E. Pian, Jennifer S. Ferreira, Thomas H. Kunz

KIP Articles

No abstract provided.

Crow's Nest, March 4, 2013, Crow's Nest Staff

Crow's Nest

The March 4, 2013, issue of the Crow's Nest.

Bacterial Colonization And Extinction On Marine Aggregates: Stochastic Model Of Species Presence And Abundance, Andrew M. Kramer, M. Maille Lyons, Fred C. Dobbs, John M. Drake

Integrative Biology Faculty and Staff Publications

Organic aggregates provide a favorable habitat for aquatic microbes, are efficiently filtered by shellfish, and may play a major role in the dynamics of aquatic pathogens. Quantifying this role requires understanding how pathogen abundance in the water and aggregate size interact to determine the presence and abundance of pathogen cells on individual aggregates. We build upon current understanding of the dynamics of bacteria and bacterial grazers on aggregates to develop a model for the dynamics of a bacterial pathogen species. The model accounts for the importance of stochasticity and the balance between colonization and extinction. Simulation results suggest that while …

Why Some Physicians Accept Healthcare It And Others Resist It: An Activity-Theoretic Analysis., Anol Bhattacherjee, Christopher Davis, Neset Hikmet

USF St. Petersburg Campus Faculty Publications

This paper examines why physicians react differently to the introduction of healthcare information technology (IT) in the same hospital at the same time. These diverse reactions, manifested as different forms of acceptance and resistance, are interpreted within the social-historical context of physicians’ work at a large urban hospital in the USA, using Activity Theory as the theoretical lens. While prior IT research has examined patterns of “similarities” in user behaviors, we examine user “differences” and reconcile these differences within a meta-theoretic framework. We also extend current IT usage research from voluntary to mandatory setting and demonstrate the viability of activity …

Persistent Human Herpesvirus-6 Infection In Patients With An Inherited Form Of The Virus, Shara N. Pantry, Maria M. Medveczky, Jesse H. Arbuckle, Janos Luka, Jose G. Montoya, Jianhong Hu, Rolf Renne, Daniel Peterson, Joshua C. Pritchett, Dharam V. Ablashi, Peter G. Medveczky

Molecular Medicine Faculty Publications

Human herpesvirus-6 (HHV-6)A and 6B are ubiquitous betaherpesviruses viruses with lymphotropic and neurotropic potential. As reported earlier, these viruses establish latency by integration into the telomeres of host chromosomes. Chromosomally integrated HHV-6 (CIHHV-6) can be transmitted vertically from parent to child. Some CIHHV-6 patients are suffering from neurological symptoms, while others remain asymptomatic. Four patients with CIHHV-6 and CNS dysfunction were treated with valganciclovir or foscarnet. HHV-6 replication was detected by reverse transcriptase polymerase chain reaction amplification of a late envelope glycoprotein. In this study we also compared the inherited and persistent HHV-6 viruses by DNA sequencing. The prevalence of …