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Cancer-Related Risk Behaviors And Screening Intention Among Recreational Sport Athletes, Aldenise P. Ewing

USF Tampa Graduate Theses and Dissertations

The recreational sports arena provides a venue for young adults to increase physical activity and engage in a socially supportive environment. These are both important ways to decrease the risk for chronic diseases. It is assumed that physically active individuals lead healthier lifestyles and are more attuned to their long-term health needs. Recreational sport athletes also engage in risks for adverse cancer outcomes through increased sun exposure, intake of unhealthy diets, and recreational tobacco and alcohol use. It was of interest to assess cancer-related risk factors, cancer knowledge, and theory of planned behavior constructs in this group.

This study involved …

Radon (222rn) Concentrations In The Touristic Jumandy Cave In The Amazon Region Of Ecuador, Felipe Alejandro García Paz, Yasser Alejandro Gonzalez Romero, Rasa Zalakeviciute

KIP Articles

This work consists of the detection and quantification of the concentration levels of radioactive gas radon-222 (222Rn) of natural origin, as well as the determination of the critical points and the estimation of the effective dose absorbed by the tourists and guides inside the Jumandy cavern in Napo, Ecuador. According to the feasibility map of uranium of Ecuador, the study area is located in one of the top-priority areas for obtaining uranium, suggesting possible radioactivity in this unstudied region. The measurements were carried out from July to October of 2017, in three different monitoring points inside the cavern. The average …

Chemical Tools And Treatments For Neurological Disorders And Infectious Diseases, Andrea Lemus

USF Tampa Graduate Theses and Dissertations

Neurological disorders have multiple etiologies such as genetics and age. Stress related disorders are becoming more common and diagnosed more often. Mental health disorders are no longer being treated as purely psychological. Mechanisms into the underlying factors of these disorders continue to bring this area to new frontiers. Chapter 2 of this dissertation focuses on the efforts made to prove the association of the protein FKBP51 to the stress response. We synthesized and used a molecular tool to discover and prove these interactions.

The study of neurodegenerative diseases is of continued importance as the world reaches record numbers of an …

Antarctic Deep Sea Coral And Tropical Fungal Endophyte: Novel Chemistry For Drug Discovery, Anne-Claire D. Limon

USF Tampa Graduate Theses and Dissertations

Considered the pulse controlling the biological interactions and contributing to the ecological survival of organisms, natural products have intrigued, challenged, and stimulated the scientific and non-scientific minds for millennia. Drug resistance and the lack of suitable potent drugs against neglected tropical diseases further motivate the biological activity assessment of these secondary metabolites, when possible.

This thesis describes the chemical investigation of two marine organisms and the elucidation of eight novel structures.

The study of a deep sea Antarctic coral unveils six novel terpenoid structures from three different molecular classes: sesquiterpenoid alcyopterosins, a triterpene steroid, and three prostaglandins. While mass availability …

The Weekly Challenger, November 21, 2019, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The November 21, 2019, issue of The Weekly Challenger.

Cultural Competence: Reflections And Self-Efficacy In A Preservice Teacher-Education Program, Jennifer Fernandez

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to explore preservice teachers’ sense of confidence working with English Learners, and the ability to transfer that confidence to self-efficacy in cultural competence. Specifically, the study evaluated an infused ESOL endorsement program integrated into a teacher preparation program at a local Florida state college. The qualitative study derived information from retrospective data from past assignments in two ESOL specific courses required for students in two different programs, Elementary Education, and Exceptional Student Education. Additionally, data were analyzed from semi-structured interviews in which five preservice teachers participated.

Findings uncovered four major themes and multiple subthemes. …

Risky Times And Spaces: Settler Colonialism And Multiplying Genocide Prevention Through A Virtual Indian Residential School, Andrew Woolford, Adam Muller, Struan Sinclair

Genocide Studies and Prevention: An International Journal

In this article, we examine how the logic of genocide prevention aligns with a settler colonial logic of elimination. We examine how the exclusion of cultural techniques of destruction from consideration contributes to the logic of elimination, and we suggest this is, in part, a structural problem built into the logic of genocide prevention. Along these lines, we interrogate linear and molar approaches to genocide prevention and propose, in addition to existing macro-level strategies, a molecular, everyday ethos of genocide prevention that is attuned to genocidal intimacies and seeks to foster anti-genocide habits and practices. In so doing, we argue …

Closing America’S Retirement Savings Gap: Nudging Small Business Owners To Adopt Workplace Retirement Plans, Peter W. Kirtland

USF Tampa Graduate Theses and Dissertations

Small businesses, with 50 or fewer employees, rarely offer workplace retirement plans. The lack of effective retirement plan options leads to employee stress, financial strain, and social instabilities. The purpose of this research is to study why small business owners make poor decisions about workplace retirement plans. The study evaluates the information supply chain and determines that financial advisors are a critical information delivery mechanism. However, they do not take the time to discuss the various retirement plan options available with the small business owners which leads to lack of plan adoption.

Elaborated Action Design Research (eADR) research methods are …

Risk Of Major Adverse Cardiovascular Events And Major Hemorrhage Among White And Black Patients Undergoing Percutaneous Coronary Intervention, Anping Cai, Chrisly Dillon, William B. Hillegass, Mark Beasley, Brigitta C. Brott, Vera A. Bittner, Gilbert J. Perry, Ganesh V. Halade, Sumanth D. Prabhu, Nita A. Limdi

Internal Medicine Faculty Publications

Background: Data on racial disparities in major adverse cardiovascular events (MACE) and major hemorrhage (HEM) after percutaneous coronary intervention are limited. Factors contributing to these disparities are unknown. Methods and Results: PRiME-GGAT (Pharmacogenomic Resource to Improve Medication Effectiveness–Genotype-Guided Antiplatelet Therapy) is a prospective cohort. Patients aged ≥18 years undergoing percutaneous coronary intervention were enrolled and followed for up to 1 year. Racial disparities in risk of MACE and HEM were assessed using an incident rate ratio. Sequential cumulative adjustment analyses were performed to identify factors contributing to these disparities. Data from 919 patients were included in the analysis. Compared with …

Continuous Glucose Monitoring Based On Remote Sensing Of Variations Of Parameters Of A Sic Implanted Antenna, Fabiola Araujo Cespedes, Stephen E. Saddow, Christopher Leroy Frewin, Erdem Topsakal

USF Patents

A passive sensing continuous glucose monitoring system and method of use thereof. The system includes a passive antenna formed of biocompatible silicon carbide (SiC), modeled to a desired frequency, which is permanently implanted subcutaneously. The system further includes an external-to-the-body transmitting antenna to detect changes in the blood glucose level by sending a radio signal at the frequency of the implanted passive antenna into the body. This signal is received and reflected by the passive antenna, and the reflected signal is then received at an external-to-the-body receiving antenna. Changes in the glucose level lead to modifications in the signal and …

Crow's Nest, November 18, 2019, Crow's Nest Staff

Crow's Nest

The November 18, 2019, issue of the Crow's Nest.

Development Of A Voxel-Based Monte Carlo Radiation Dosimetry Methodology For A Targeted Alpha Particle Therapy, Christopher John Tichacek

USF Tampa Graduate Theses and Dissertations

The use of targeted ligands to deliver radioisotopes directly to tumor cells is a promising therapeutic strategy. Because of the short path length and high LET of alpha particles, targeted alpha particles are ideal for treating metastatic disease while minimizing damage to non-targeted tissues. However, clinical methods for determining 3D radiation dosimetry in patients with multiple metastatic lesions are needed to support clinical translation of novel targeted alpha particle therapies for personalized treatment, especially in patients that have previously received radiotherapy. Recently interest in novel radiopharmaceutical development has grown significantly. However, compared to external beam radiation therapy, progress in customizing …

Effect Of Atypical Protein Kinase C Inhibitor (Dnda) On Cell Proliferation And Migration Of Lung Cancer Cells, Raja Reddy Bommareddy

USF Tampa Graduate Theses and Dissertations

Lung cancer is the second most common cancer, and it is the leading cause of cancer death in both men and women. Elevated levels of PKC-ι and FAK are implicated in the progression of lung cancer and involved in cell proliferation, apoptosis, cell survival, and cell migration processes. Lung cancer diagnosis typically occurs in the late stages, which limits the treatment options. Hence, there is a dire need to develop drugs that are effective and safe to treat lung cancers. We used a novel aPKC inhibitor named DNDA (3,4-amino-2,7 napthalene disulfonic acid) to study the role of atypical PKCs (aPKCs) …

The Activity And Structure Of Cu2+-Biomolecules In Disease And Disease Treatment, Darrell Cole Cerrato

USF Tampa Graduate Theses and Dissertations

Despite its relatively low concentration in the human body, copper is an essential transition metal ion. Under normal circumstances, it is a well-regulated trace element that is introduced via diet or environment depending on the organism. Its strong reactivity and binding to some biologically essential chemicals can be detrimental to the host organism. Herein the oxidative chemistry of copper and its possible prevention in humans and agricultural organisms is discussed, as well as the potential avenues as metal-targeting disease treatment via novel-peptide and peptoid products.

In the first study, copper is implicated in the progression and onset of Alzheimer’s disease. …

Lung Cancer Cells Survive Egfr Tki Exposure Through Upregulation Of Cholesterol Synthesis, Mark Howell

USF Tampa Graduate Theses and Dissertations

Lung cancer is the number one cause of cancer related death in both males and females. About 20% of all non-small cell lung cancer (NSCLC) patients are expected to harbor an epidermal growth factor receptor (EGFR) activating mutation. EGFR inhibitors have been shown to provide clinical benefits over chemotherapy for lung cancer patients with EGFR activating mutations. However, despite the initial clinical responses to these EGFR targeted therapies, long-term efficacy is not possible because acquired drug resistance hampers the effectiveness of these therapies. We found that a fiber inspired smart scaffold (FiSS) platform established in our laboratory allows growth of …

Construction Of G-Quadruplexes Via Self-Assembly: Enhanced Stability And Unique Properties, Ying He

USF Tampa Graduate Theses and Dissertations

This dissertation mainly contains three parts: 1) The construction of well-defined G8-octamers through the monomer conformational design. 2) The construction of cross-layer interactions in the G8-octamer for enhanced stability in H-bond competitive solvents. 3) Design and synthesis of 8-triazole guanosine with photoluminescent properties.

Through the structural conformational design, we have developed a new class of guanosine derivatives with modification on guanine (8-aryl) and ribose (2’,3’-isopropylidene). This unique design has led to the formation of the first discrete G8-octamer with structure characterized by NMR, MS and single crystal X-ray diffraction. The selectivity between monovalent (K+) and divalent cat-ions (Ba2+ and Sr2+) …

High Ammonia Strength Wastewater Treatment Using Algae, Bacteria And Ion Exchange, Nadezhda Zalivina

USF Tampa Graduate Theses and Dissertations

Nitrogen pollution has been considered one of the major problems of the 21st century. Discharge of nitrogen from improperly treated wastewaters into surface water bodies causes eutrophication and hypoxia, which results in significant environmental, public health and economic damages. In addition to the incoming flow, wastewater treatment plants generate internal highly concentrated ammonium streams, such as anaerobic digestion sidestream. As a current practice, sidestream without prior treatment is returned to the head of the plant, which increases the total incoming nitrogen load by 20-30% and often exceeds the treatment capacity. The most commonly used conventional biological nitrogen removal processes are …

Innovating Green Stormwater Infrastructure For Nutrient Management: Long-Term Field And Modeling Studies Of Conventional And Modified Denitrifying Bioretention Systems, Emma V. Lopez-Ponnada

USF Tampa Graduate Theses and Dissertations

Urban stormwater and nutrient management are increasingly important topics to address globally, as coastal urbanization increases, disturbing the natural landscape, hydrology, and water quality. Untreated urban stormwater runoff carries pollutants that enter our waterways, such as rivers and marine environments, which serve as drinking water sources, recreational sites, and locations for economic livelihood. One pollutant and nutrient of concern for water quality is reactive nitrogen (N). Since pre-industrial time, reactive nitrogen has doubled from human activity. When found in excess in waterways, nitrogen causes an overabundant growth of algae, which can result in eutrophic and hypoxic conditions, impacting ecosystems, human …

The Peculiar Nature Of Florida’S Sandhill Wetlands, Ponds & Lakes— Their Ecohydrology, Relationship With The Regional Aquifer & Importance Within The Landscape., Renae Starr Nowicki

USF Tampa Graduate Theses and Dissertations

This dissertation explores the ecohydrology of Florida’s peculiar and poorly studied sandhill wetland and water features, particularly those located in west-central Florida. The primary research goals include: compilation and summarization of the available ecohydrologic information for features across Florida; comparison of water level and water geochemistry data between sandhill wetlands and waters and the regional aquifer to provide evidence of regional hydrologic control; and use of geophysical applications to examine the hydraulic connections between sandhill wetlands and waters and the regional aquifer.

From this research, a natural history of sandhill wetland and water ecohydrology is presented, highlighting: the differences between …

Rescue Of Hearing And Protection Of Auditory Structures From Noise-Induced Hearing Loss, Reza Amanipour

USF Tampa Graduate Theses and Dissertations

Hearing loss due to exposure to high level sound is a major health problem that causes permanent hearing impairment and has a significant impact on job productivity and quality of life. A large population suffers from noise-induced hearing loss (NIHL), a disorder for which there is currently no FDA-approved prevention, treatment or cure. The goal of my dissertation work is to provide insights into the effects of noise trauma on hearing abilities of normal hearing subjects, and determine how a new therapeutic compound (mGlu7 modulator) can protect and/or prevent loss of, or damage to sensory cells and brain neurons, including …

Agenda And Reports, Juvenile Welfare Board Regular Board Meeting, November 14, 2019, Juvenile Welfare Board Of Pinellas County

Juvenile Welfare Board Agendas, Minutes, and Historical Audits

Agenda for the November 14, 2019, meeting of the Juvenile Welfare Board of Pinellas County's regular Board. Includes reports and presentations to review before the meeting.

The Role Of Atypical Protein Kinase C In Colorectal Cancer Cells Carcinogenesis, S M Anisul Islam

USF Tampa Graduate Theses and Dissertations

Colorectal cancer (CRC) is the third most common malignancy and the fourth most common cause of cancer-related death worldwide. CRC is a life-threatening disease due to therapy-resistant cancerous cells. The exact mechanisms of cell growth, survival, metastasis and inter & intracellular signaling pathways involved in CRC are still a significant challenge. Moreover, the treatment of metastatic CRC considered palliative for many years aimed for an improved life, with little hope of a cure, highlighting the need for developing novel targeted therapy for CRC. Hence, investigating new molecular mechanism(s) that lead to colorectal carcinogenesis may give insight into the therapeutic target. …

Perceived Discrimination And Cardiovascular Outcomes In Blacks: A Secondary Data Analysis Of The Heart Score Study, Marilyn Aluoch

USF Tampa Graduate Theses and Dissertations

Despite the consistent reduction in morbidity and mortality associated with cardiovascular disease (CVD) over the last four decades, CVD remains the leading cause of death globally. In the United States, Blacks are disproportionately affected by CVD compared to Whites. Blacks are also more likely to report incidence of perceived discrimination. Perceived discrimination has been linked to cardiovascular risk factors such as smoking, hypertension (HTN), hyperlipidemia, and obesity. However, the relationship between perceived discrimination and cardiovascular outcomes such as stroke, myocardial infarction, acute ischemic syndrome, coronary revascularization, and cardiac death remains unclear. The primary goal of this study was to examine …

Introducing A Mobile Health Care Platform In An Underserved Rural Population: Reducing Assimilations Gaps On Adoption And Use Via Nudges, Joseph Hodges

USF Tampa Graduate Theses and Dissertations

Rural communities are often overlooked when it comes to offering cutting edge consumer healthcare technologies. Mobile applications usually exclude populations in rural demographics due to the infrastructure requirements and available technology in the region. The population studied is a low income rural health plan in southwest Georgia. They are uniquely considered as they have the highest healthcare costs in the U.S. and are compared to healthcare costs among higher income populations like Vail, Colorado. Innovations, such as mobile healthcare applications, have the capacity to offset some of these costs, but even if adoption occurs, this does not guarantee use will …

Untapped Potential Of Gorgonian Octocorals For Detecting Environmental Change In Biscayne National Park, Florida, Usa, Selena A. Kupfner Johnson

USF Tampa Graduate Theses and Dissertations

One consequence of dramatic stony-coral loss has been recognition that gorgonian octocorals (Anthozoa: Octocorallia) have emerged among the dominant reef fauna. However, gorgonians are notoriously difficult to field-identify and consequently have been underrepresented in most monitoring efforts resulting in a lack of long-term data. The rich diversity of habitats, close proximity to the urban center of Miami, and connectivity to other areas of Florida have made Biscayne National Park an active location for reef research since its establishment in 1968. As such, a plethora of data (e.g., museum specimen and species abundance data) has been collected and stored in archives …

Student Attitudes And Behaviors Regarding Academic Dishonesty, Kelly A. Pearson

USF Tampa Graduate Theses and Dissertations

This research study investigated the relationship between students’ attitudes toward academic dishonesty and their self-reported cheating behaviors. Additionally, the study investigated the potential differences between gender and the academic variables class level and cumulative GPA and both students’ attitudes toward academic dishonesty and their self-reported cheating behaviors. This quantitative study analyzed secondary data from a Spring 2014 administration of the Academic Integrity Student Survey (AISS) to examine the attitudes and behaviors of undergraduate level students (N = 574) at a large, four-year, public, research intensive institution in West-Central Florida.

Results indicated a statistically significant correlation between students’ attitudes toward academic …

An Ecology Of Care: Training In Dependence And Caretaking In The Witcher 3: Wild Hunt, Elizabeth Rossbach

USF Tampa Graduate Theses and Dissertations

This project investigates the popular open-world fantasy RPG, The Witcher 3: Wild Hunt (CD Projekt RED 2015) and the ways in which the Witcher 3 brings questions of care and dependence to a digital medium so often thought of in terms of violence and/or mastery. Much of the previous discourse on video games, particularly role-playing games, has tended to center on violence and what this might mean for players behavior or the potential real world effects of this violence. Departing from a focus on violence I argue that the Witcher 3, reveals the potentials of open-world RPG video games to …

The Progressive Transformation Of Medellín- Colombia: A Successful Case Of Women's Political Agency, María Auxiliadora González-Malabet

USF Tampa Graduate Theses and Dissertations

Medellín, Colombia, once one of the most corrupt and violent cities in the world, is now one of the most progressive and democratic cities in South America. This transformation was due to the mobilization of women’s movements and the influx of women in the city’s executive branch. Female political agency and new urban development programs reshaped democratic practices for the citizenry. This research examines the robust association between women’s organizations, women from Compromiso Ciudanano (CC), and a solid and active civil society. The theoretical framework covers democratization, good governance, and Latin American/Indigenous Feminism. The sources include interviews, polls, news articles, …

Disciplinary D/Discourses: Navigating And Negotiating Disciplinary Paradigms, Michael R. P. Bailey

USF Tampa Graduate Theses and Dissertations

Over the past twenty-five years, in the United States, zero-tolerance policies that were initially implemented to deter gun violence and drugs in schools have expanded to include a wide range of discretionary offenses such as disrespect and defiance. As a result, many students have been denied access to educational opportunities, been excluded from their peers, and had their lives irrevocably changed due to systemic sanctioning of exclusionary practices. Educators, who are caught between competing societal demands, job expectations, and ethical beliefs about their profession are tasked with balancing the instructional and interactional components of their work in an attempt to …

Promoting Healthy Sleep Practices Among Parents Of Young Children: A Preliminary Randomized Controlled Trial, Kristin Lynn Edwards

USF Tampa Graduate Theses and Dissertations

One of the most significant and underrecognized public health concerns in young children is related to the consequences of inadequate sleep. Inadequate sleep may result in problems related to behavioral regulation, executive functioning, and academic performance. ‘Sleep hygiene’, a term that describes consistent daytime and nighttime practices that promote healthy sleep, has been found to significantly increase sleep duration and improve sleep quality in the pediatric population. Researchers have found that many parents have a poor understanding of sleep hygiene. The purpose of this study was to determine if an educational intervention increased parental knowledge and practices of sleep hygiene …