Covid-19 Vaccines And Thrombosis—Roadblock Or Dead-End Street?, Kenneth Lundstrom, Debmalya Barh, Bruce D. Uhal, Kazuo Takayama, Alaa A. A. Aljabali, Tarek Mohamed Abd El-Aziz, Amos Lal, Elrashdy M. Redwan, Parise Adadi, Gaurav Chauhan, Samendra P. Sherchan, Gajendra Kumar Azad, Nima Rezaei, Ángel Serrano-Aroca, Nicolas G. Bazan, Sk. Sarif Hassan, Pritam Kumar Panda, Pabitra Pal Choudhury, Damiano Pizzol, Ramesh Kandimalla, Wagner Baetas-Da-Cruz, Yogendra Kumar Mishra, Giorgio Palù, Adam M. Brufsky, Murtaza M. Tambuwala, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Two adenovirus-based vaccines, ChAdOx1 nCoV-19 and Ad26.COV2.S, and two mRNA-based vaccines, BNT162b2 and mRNA.1273, have been approved by the European Medicines Agency (EMA), and are invaluable in preventing and reducing the incidence of coronavirus disease-2019 (COVID-19). Recent reports have pointed to thrombosis with associated thrombocytopenia as an adverse effect occurring at a low frequency in some individuals after vaccination. The causes of such events may be related to SARS-CoV-2 spike protein interactions with different C-type lectin receptors, heparan sulfate proteoglycans (HSPGs) and the CD147 receptor, or to different soluble splice variants of the spike protein, adenovirus vector interactions with the …

The Signal Peptide Of The Amyloid Precursor Protein Forms Amyloid-Like Aggregates And Enhances Aβ42 Aggregation, Kundlik Gadhave, Taniya Bhardwaj, Vladimir N. Uversky, Michele Vendruscolo, Rajanish Giri

Molecular Medicine Faculty Publications

Signal sequences are short peptides at the N terminus of proteins destined for the secretion pathway. Typically, after cleavage by peptidases, signal peptides are degraded by intra-membrane proteases. In some cases, however, signal peptides can be processed further and released into the endoplasmic reticulum, secretion pathways, or cytoplasm. The consequences of these processes remain unclear, in particular considering that dysregulated signal peptides could potentially aggregate and induce cytotoxicity. To investigate this problem, we study the signal peptide of the amyloid precursor protein (APP), which originates the Alzheimer’s β-amyloid (Aβ) peptide. Our results show that this signal peptide (residues 1–17 of …

Consent To Publish Work In Digital Commons At University Of South Florida, University Of South Florida Libraries

Digital Commons @ University of South Florida Guidelines

No abstract provided.

What Is The Role Of Cyber Operations In Information Warfare?, Emilio Iasiello

Journal of Strategic Security

Much attention has been focused on the potential consequences of cyber attacks against critical infrastructure and the use of cyber weapons as an asymmetric equalizer. However, as a capability considered to be under the larger umbrella of an information operations (IO)/information warfare (IW) campaign, how significant a weapon is cyber for the strategist in an information environment? As observed in recent IO/IW campaigns targeting U.S. elections in 2016 and 2020, lack of any discernable disruptive cyber attacks may have provided an answer to this, as a cyber power purposefully elected not to implement attacks. Instead, cyber espionage was used, and …

Evaluating The Impact Of Incentives On Clinical Trial Participation: Protocol For A Mixed Methods, Community-Engaged Study, Jerome T. Galea, Karah Y. Greene, Brandon Nguyen, Andrea N. Polonijo, Karine Dubé, Jeff Taylor, Christopher Christensen, Zhiwei Zhang, Brandon Brown

Social Work Faculty Publications

Background: Monetary incentives in research are frequently used to support participant recruitment and retention. However, there are scant empirical data regarding how researchers decide upon the type and amount of incentives offered. Likewise, there is little guidance to assist study investigators and institutional review boards (IRBs) in their decision-making on incentives. Monetary incentives, in addition to other factors such as the risk of harm or other intangible benefits, guide individuals’ decisions to enroll in research studies. These factors emphasize the need for evidence-informed guidance for study investigators and IRBs when determining the type and amount of incentives to provide to …

Closing Delivery Gaps In The Treatment Of Tuberculosis Infection: Lessons From Implementation Research In Peru, Courtney M. Yuen, Ana Karina Millones, Daniela Puma, Judith Jimenez, Jerome T. Galea, Roger Calderon, Gabriela S. Pages, Meredith B. Brooks, Leonid Lecca, Tom Nicholson, Mercedes C. Becerra, Salmaan Keshavjee

Social Work Faculty Publications

Background: Targeted testing and treatment of TB infection to prevent disease is a pillar of TB elimination. Despite recent global commitments to greatly expand access to preventive treatment for TB infection, there remains a lack of research on how best to expand preventive treatment programs in settings with high TB burdens.

Methods: We conducted implementation research in Lima, Peru, around a multifaceted intervention to deliver TB preventive treatment to close contacts of all ages, health care workers, and people in congregate settings. Key interventions included use of the interferon gamma release assay (IGRA), specialist support for generalist physicians at primary-level …

A Review Investigating The Relationship Between Cannabis Use And Adolescent Cognitive Functioning, Elena Cyrus, Makella S. Coudray, Sandra Kiplagat, Yandra Mariano, Ines Noel, Jerome T. Galea, Dexter Hadley, Jessy G. Dévieux, Eric Wagner

Social Work Faculty Publications

No abstract provided.

Incident Tuberculosis Diagnoses In Children At High Risk For Disease, Milagros Wong, Julia M. Coit, Milagros Mendoza, Silvia S. Chiang, Helen Marin, Jerome T. Galea, Leonid Lecca, Molly F. Franke

Social Work Faculty Publications

We followed 35 children meeting a research definition for unconfirmed tuberculosis (TB) but in whom a pediatric pulmonologist did not diagnose or treat TB. After a median follow-up of 16.4 months, most children were not diagnosed with TB following a comprehensive evaluation. However, 2 were diagnosed with TB, demonstrating high TB risk (6%; exact 95% CI, 1%–19%). In some contexts, researchers may wish to supplement these research definitions with clinical decision data and longitudinal follow-up in order to improve specificity.

Prediction Tool To Identify Children At Highest Risk Of Tuberculosis Disease Progression Among Those Exposed At Home, Meredith B. Brooks, Leonid Lecca, Carmen Contreras, Roger Calderon, Rosa Yataco, Jerome Galea, Chuan-Chin Huang, Megan B. Murray, Mercedes C. Becerra

Social Work Faculty Publications

Background: There is a dearth of research to understand which children, among those who are exposed at home to tuberculosis (TB), are at the highest risk of TB disease, to tailor care. We sought to identify predictors of TB progression in children.

Methods: We conducted a prospective cohort study of children living with adults with pulmonary TB in Lima, Peru (2009–2012). We applied classification and regression tree analysis to examine potential predictors of incident TB disease during 12 months in 3 age groups (0–4, 5–9, and 10–14 years). We calculated the relative risk (RR) for top predictors in each age …

A Non-Specialist Depression Care Pathway For Adolescents Living With Hiv And Transitioning Into Adult Care In Peru: A Nested, Proof Of Concept Pilot Study, Jerome T. Galea, Carmen Contreras, Milagros Wong, Karen Ramos, Valentina Vargas, Hugo Sánchez, Renato A. Errea, Leonid Lecca, Molly F. Franke

Social Work Faculty Publications

Background: Adolescents living with HIV (ALWH) are disproportionally impacted by depression, experiencing worse HIV outcomes. Integrated depression and HIV care may support antiretroviral adherence. This study pilot tested for proof of concept a basic depression care pathway for ALWH to inform depression care integration with HIV services in Peru.

Methods: ALWH were screened for depression with the Patient Health Questionnaire-9 (PHQ-9). Participants with PHQ-9 scores of ⩾10 or suicidal ideation (SI) were eligible for Psychological First Aid (PFA) delivered by non-mental health specialists. Participants with PHQ-9 re-assessments of ⩾20 or SI were referred to specialized services.

Results: Twenty-eight (11 female, …

Impact Of The Sars-Cov-2 Pandemic On Adolescents Living With Hiv In Lima, Peru, Renato A. Errea, Milagros Wong, Liz Senador, Alicia Ramos, Karen Ramos, Jerome T. Galea, Leonid Lecca, Hugo Sánchez, Carlos Benites, Molly F. Franke

Social Work Faculty Publications

Adolescents living with HIV (ALWH) have lower rates of virologic suppression and higher rates of immunologic decline compared to their older counterparts, potentially placing them at high-risk for developing severe SARS-CoV-2 disease. ALWH who are transitioning to adult care face additional challenges to remaining in care and adhering to treatment. In this special section we report the experiences of ALWH in the process of transitioning to adult HIV services during the COVID-19 pandemic. In first place, the government-mandated stay-at-home order has substantially limited access to full HIV care by restricting public transportation, HIV medication stock-outs, and the suspension of routine …

Adequately Reflecting The Severity Of Tropical Cyclones Using The New Tropical Cyclone Severity Scale, Nadia Bloemendaal, Hans De Moel, Jantsje M. Mol, Priscilla R.M. Bosma, Amy Polen, Jennifer M. Collins

School of Geosciences Faculty and Staff Publications

For decades, meteorologists and governments have been warning communities in coastal areas for an imminent tropical cyclone (TC) using the Saffir-Simpson Hurricane Wind Scale (SSHWS). The SSHWS categorizes a TC based on its maximum wind speed, and is used in defining evacuation strategies and humanitarian response. However, the SSHWS considers only the wind hazard of a TC, whereas a TC can also cause severe conditions through its high storm surges and extreme rainfall, triggering coastal and inland flooding. Consequently, the SSHWS fails to mirror the TC's total severity. This becomes evident when looking at past events such as Hurricane Harvey …

Network & Cyber Security In Hospitality And Tourism, Emmanuel Fragniere, Kamil Yagci

University of South Florida (USF) M3 Publishing

OVERVIEW

The tourism sector was transformed early on by digitalization, which makes it a very innovative area of business. At the same time, this high level of digitalization maturity makes it a very vulnerable industry in terms of cyber security. As a tourism specialist, it is therefore crucial to have a good understanding of network and cybersecurity. In this chapter, we will address this topic in an accessible and popularized manner. The goal is to understand the challenges of cybersecurity and as a tourism professional to contribute with specialists in the field to protect your business, your network, and your …

The Dual Aspect Of Technology In Tourism: Social Contradictions Surrounding The Sharing Economy And Smart Destination Development, Miha Bratec, Marco A. Celdran Bernabeu, Dejan Krizaj, Josep Ivars-Baidal, Ana B. C. Diaz, Peter Kopic, Tadej Rogelja

University of South Florida (USF) M3 Publishing

OVERVIEW

The technology and the rise of Web 2.0. enabled the meteoric rise of peer-to-peer (P2P) platforms facilitating transactions and consequential establishment of the sharing economy concept. This accelerated technological change has led to new dynamics in cities and tourist destinations such as over-tourism with the so-called arise of the sharing economy significantly fueling it. The main purpose of our chapter is to systematically review this dual aspect of technological impacts on tourism. On the one hand, we review the technological aspects that underpin the development of the sharing economy and consequential over-tourism in destinations. On the other hand, we …

Technology For Spas, Salons, And Wellness Centers, Su Gibson

University of South Florida (USF) M3 Publishing

OVERVIEW

Spas, salons and wellness centers have been slow to embrace new technologies, but guest expectations of personalization, access to information, and ease of transactions have recently spurred the creation and adoption of many technology tools within this specialized field. This chapter explores technology commonly used in this segment for managing operations, marketing, enhancing the guest experience and evaluating performance. The chapter begins with an introduction to the nature of spa, salon and wellness center operations and explains how technology is used, in general, to facilitate this high-touch arena of hospitality. Additional topics include technology for managing operations such as …

Report, University Of South Florida Libraries And The Inclusive And Equitable Pedagogy Faculty Learning Community, Fall 2021, University Of South Florida Libraries

All-Library Assessments Reports, Summaries & Misc Reports

A report on the University of South Florida Libraries' involvement with the Inclusive and Equitable Pedagogy Faculty Learning Community (IEPFLC).

2021 Baseball Media Guide, University Of South Florida. Athletic Communications Office, Brian Siegrist, Jay D'Abramo, Tom Zebold

Baseball Media Guides

The media guide for the University of South Florida's (USF) 2021 men's baseball season. Included are sections on the roster and schedule for the season, coaches and staff, player biographies, a 2020 season review, program records, program history, and USF Athletics media information. The Bulls finished with a 31-30 record.

Socioeconomic Challenges Of California Strawberry Production And Disease Resistant Cultivars, Julie Guthman, Estelí Jiménez-Soto

School of Geosciences Faculty and Staff Publications

Strawberries are the 4th highest grossing crop in California and supply 90% of US strawberries. But the industry's long reliance on the use of chemical fumigants to control soil disease, nematodes and weeds is being threatened by increased regulation of these fumigants, leading to urgent efforts to develop and test non-chemical alternatives to fumigation, such as disease resistant cultivars. Many of these technologies are promising ecologically, but making them economically viable for growers is more challenging, especially in light of the socioeconomic context of strawberry production in California that has created a state of lock-in for a sustainability transition. This …

Business For Good: How Universities Can Catalyze The B Corp Movement, Emma C. Jacobs

USF St. Petersburg campus Honors Program Theses (Undergraduate)

The burgeoning B Corp movement is transforming the global economy using the power of business to solve social, environmental, and economic problems. Higher education institutions are uniquely positioned to educate the business leaders of tomorrow on this rising method of "business unusual". Universities can play a key role in catalyzing the B Corp movement, which advocates for corporate social and environmental responsibility, accountability, and transparency. This paper describes how universities can effectively educate and prepare the next generation of changemakers through incorporating what are referred to as B Corp programs. Though they take many unique forms, university B Corp …

Racism In Medicine And Science, Samantha Soriano

USF St. Petersburg campus Honors Program Theses (Undergraduate)

The history of racism and prejudice in the United States is not limited to segregation, slavery, and discrimination. Medical and scientific racism continue to disproportionately affect Black and Indigenous People of Color (BIPOC). BIPOC have been used for scientific advancement without full disclosure of potential harm or adequate compensation. Scientists and medical providers have dehumanized minority individuals by disrespecting their autonomy and targeting vulnerable populations. This thesis consists of a literature review that surrounds the history of medical and scientific exploitation of people of color, ethical guidelines surrounding research, eugenics, and how assumptions affect the quality of care that minority …

A Closer Look: Case Studies In Trauma Survivorship, Mckenna K. Minarcin

USF St. Petersburg campus Honors Program Theses (Undergraduate)

This paper focuses on a case study analysis of several traumatic experiences as told by survivors. Through this case study approach, this paper attempts to humanize the often heavily statistical world of trauma research. The first portion of this thesis is comprised of research surrounding current trauma research and coping mechanisms (both positive and negative) associated with trauma response. These methods include both traditionally accepted practices and alternative treatments, as well as the financial, emotional, and physical implications of these treatment methods. The second portion of this thesis is comprised of the narratives previously mentioned, which were each obtained through …

"Forgotten Children": Siblings Of Adolescents With Eating Disorders, Evin Janik

USF St. Petersburg campus Honors Program Theses (Undergraduate)

Almost 30 million individuals in the United States will have an eating disorder in their lifetime. Of those 30 million, 10,200 individuals will die a year as a direct result of the eating disorder (Deloitte Access Economics, 2020). To discover a way to help those suffering, there has been research into a variety of treatment options. One of the most common treatments is Family-Based Therapy which often dives into the parent and diagnosed child’s relationship. In this form of treatment there is often little focus on the impact of the diagnosis on the sibling(s). In this study we will be …

The Significance Of Deaf Culture: A Bioethical Analysis Of Pediatric Cochlear Implants, Samantha Kappaz

USF St. Petersburg campus Honors Program Theses (Undergraduate)

No abstract provided.

The Role Of Race And Class As Predictors Of Police Violence: A Case Study Of West-Central And Eastern Florida, Matthew Viera

USF St. Petersburg campus Honors Program Theses (Undergraduate)

United States Law Enforcement has come under the watchful eye of the public in recent years due to the Ferguson Riots of 2014 as well as nation-wide protests during the summer of 2020, following the death of George Floyd, a man who died at the hands of police for the suspected use of a fake $20 bill. Given that the contemporary police force appears to be engaging in increasingly more violent interactions with the public, specifically the poor and people of color, it is critical to observe and assess the practices of police officers within cities that are becoming more …

Russo-Ukrainian Patterns Of Genocide In The Twentieth Century, Amos Fox

Journal of Strategic Security

Russo-Ukrainian relations in the 20th Century are dominated by genocide. Using Raphel Lemkin and Martin Shaw as a guide, one finds that Russo-Ukrainian relations during the 20th Century was a long period of genocidal action, linked by periods of punctuated genocides. These genocides included several political genocides that quelled Ukrainian nationalism and independence and kept it subjugated to Soviet Russia. Soviet Russia's genocide during the 20th Century was a carryover from Imperial Russia treatment of Ukraine, the arch of which carries over into today's relations between the two countries. Understanding this long period of genocide helps make sense of the …

A Decade Of Gomri Dispersant Science: Lessons Learned And Recommendations For The Future, Antonietta Quigg, John W. Farrington, Sherryl Gilbert, Steven A. Murawski, Vijay T. John

Marine Science Faculty Publications

Dispersants are among a number of options available to oil spill responders. The goals of this technique are to remove oil from surface waters in order to reduce exposure of surface-dwelling organisms, to keep oil slicks from impacting sensitive shorelines, and to protect responders from volatile organic compounds. During the Deepwater Horizon response, unprecedented volumes of dispersants (Corexit 9500 and 9527) were both sprayed on surface slicks from airplanes and applied directly at the wellhead (~1,500 m water depth). A decade of research followed, leading to a deeper understanding of dispersant effectiveness, fate, and effects. These studies resulted in new …

Usft 2021-2022 Usf Libraries Annual Report, Usf Libraries

Library Annual Reports

No abstract provided.

Utilization, Timing, And Outcomes Of Brca Genetic Testing Among Women With Newly Diagnosed Breast Cancer From A National Commercially Insured Population: The Aboard Study, Joanne Armstrong, Kristian Lynch, Katherine S. Virgo, Marc D. Schwartz, Sue Friedman, Marleah Dean Kruzel, James E. Andrews, Elizabeth Bourquardez Clark, Joanna Clasen, Jessica Conaty, Olivia Parrillo, Rebecca Sutphen

School of Information Faculty Publications

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Methods:

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Transcriptional Host–Pathogen Responses Of Pseudogymnoascus Destructans And Three Species Of Bats With White-Nose Syndrome, Christina M. Davy, Michael E. Donaldson, Hana Bandouchova, Ana M. Breit, Nicole A.S. Dorville, Yvonne A. Dzal, Veronika Kovacova, Emma L. Kunkel, Natália Martínková, Kaleigh J.O. Norquay, James E. Paterson, Jan Zukal, Jiri Pikula, Craig K.R. Willis, Christopher J. Kyle

KIP Articles

No abstract provided.

How To Lie With Coronavirus Statistics: Campbell's Law And Measuring The Effects Of Covid-19, Joel Best

Numeracy

Campbell's Law warns that when measurements become consequential those whose performance is being measured may try to skew the results. This case study examines the Trump administration's efforts to present COVID-19 statistics that would discourage restricting economic activities and encourage reopening the economy.