Digital Commons Network^™

An Examination Of Stormwater Quality And Quantity In Austin Area Creeks, Weizhen Zhu, Roger Glick

KIP Articles

No abstract provided.

Crow's Nest, January 17, 2022, Crow's Nest Staff

Crow's Nest

The January 17, 2022, issue of the Crow's Nest.

Educating Consumers And Producers Of Data: Review Of Making Sense Of Numbers By Jane E. Miller (2022), Andrew J. Miller

Numeracy

Author Jane E. Miller has brought her considerable experience writing and teaching about numerate communication to a new textbook, Making Sense of Numbers. Miller uses clear prose, timely and authentic examples, and thought-provoking exercises to educate the next generation of consumers and producers of data, students in introductory quantitative reasoning, research methods, or data analysis courses. While the textbook does not fit the mold of a "typical" quantitative literacy course, creative instructors may find ways to use it in innovative quantitative literacy, data literacy, or introductory data science courses.

Author’S Reflections On Making Sense Of Numbers: Quantitative Reasoning For Social Research, Jane E. Miller

Numeracy

Miller, Jane E. 2021. Making Sense of Numbers: Quantitative Reasoning for Social Research. (Los Angeles: SAGE Publications) 608 pp. ISBN 978-1544355597.

This article introduces and provides an excerpt from Making Sense of Numbers: Quantitative Reasoning for Social Research, published by Sage. The book explains and illustrates how making sense of numbers involves integrating concepts and skills from mathematics, statistics, study design, and communications, along with information about the specific topic and context under study. It teaches how to avoid making common errors of logic, calculation, and interpretation by introducing a systematic approach and a healthy dose of skepticism …

Numeracy And Financial Wellbeing During The Covid-19 Pandemic, Nora Wikoff

Numeracy

This paper examines the role of numeracy in smoothing financial difficulties during the COVID-19 pandemic. The results show that numeracy was associated with a 30% reduction in late or non-payment of bills and a 20% reduction in the odds of feeling financially squeezed. The effect of numeracy on financial wellbeing was remarkably consistent across levels of education, ethnicity, and gender, suggesting that improving numeracy levels in the population may be an effective strategy to increase financial capability across the board. However, while numerate individuals were less likely to experience financial difficulty, high numeracy did not predict narrower gaps between Whites …

Building A Social And Academic Online Bridge To Quantitatively-Rich College Coursework, Melissa Eblen-Zayas, Lin Winton

Numeracy

We describe the online summer portion of a quantitative skills bridge program focused on helping students prepare socially and academically for the transition to college. College students are increasingly asked to employ quantitative skills across the curriculum, but students arrive at college with varied preparation. Further, those with the least preparation often encounter other challenges to social belongingness and navigating their institution. In response to these needs, our institution developed a bridge program aimed at students with a broad range of interests -- not just STEM, and the program has a significant focus on community-building as well as strengthening quantitative …

Crow's Nest, January 10, 2022, Crow's Nest Staff

Crow's Nest

The January 10, 2022, issue of the Crow's Nest.

A Study Of Noise Exposures For Amusement Park Employees By Positions And Ride Categories, Danielle M. Dao

USF Tampa Graduate Theses and Dissertations

Millions of workers in the United States encounter daily noise exposures in their workplace, associated with millions of dollars in workers compensation annually. Many industries have been well studied for the presence of hazardous noise, but little exposure data exists for the amusement park industry.Major attractions found at amusement parks fall within one of three categories and in each of those categories, five employee positions are common. This thesis sought to identify if there are differences in potential employee noise exposure among the ride types and if there are differences in noise exposure among the employee positions. The analysis of …

The Weekly Challenger, January 6, 2022, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The January 6, 2022, issue of The Weekly Challenger.

Bis-Cyclic Guanidines As Antibacterial Agents, Jianfeng Cai, Peng Teng, Alekhya Nimmagadda

USF Patents

Provided are novel bis-cyclic guanidine compounds, and the use thereof for treating bacterial infection.

Tables And Figures, Laura Runge

QUANTITATIVE LITERARY ANALYSIS OF THE WORKS OF APHRA BEHN - Datasets

No abstract provided.

Chapter One: The Poetry Of Love, Laura Runge

QUANTITATIVE LITERARY ANALYSIS OF THE WORKS OF APHRA BEHN - Datasets

Chapter Abstract

Behn’s poetry corpus consists of 80 works from the long verse translation Voyage to the Isle of Love to the briefest song from the play The Wandering Nymph. It is the smallest of the genre corpora, but it proves to be formative for its representation of love. The poetry is analyzed by genres to provide a sense of Behn’s range, notably a high number of songs but also surprisingly quite a few verse epistles. The Most Frequent Word patterns highlight a language of fullness and hyperbole (all, thousand) and anatomized bodies of eyes, …

Conclusion: Words Of Passion, Laura Runge

QUANTITATIVE LITERARY ANALYSIS OF THE WORKS OF APHRA BEHN - Datasets

Chapter Abstract

The book ties the thematic threads of the chapters together with an analysis of the words of passion in Behn’s complete oeuvre. In addition to love, the word that ties the book together, Behn’s literary works explore more negative than positive passions with a focus on nervous states of apprehension, fear, doubt and sometimes hope. She also showcases violent, dangerous and extreme passions, hate, revenge and rage. The concordance data reveals, however, that Behn’s passions operate within a moral universe of Christian values where sin and guilt shadow behaviors stimulated by passion. What …

Community-Based Accompaniment For Adolescents Transitioning To Adult Hiv Care In Urban Peru: A Pilot Study, Valentina Vargas, Milagros Wong, Carly A. Rodriguez, Hugo Sanchez, Jerome T. Galea, Alicia Ramos, Liz Senador, Lenka Kolevic, Eduardo Matos, Eduardo Sanchez, Renato A. Errea, Karen Ramos, Catherine Beckhorn, Andrew Lindeborg, Carlos Benites, Leonid Lecca, Sonya Shin, Molly F. Franke

Social Work Faculty Publications

We piloted a community-based intervention to improve outcomes among adolescents living with HIV who were transitioning to adult-oriented care in Lima, Peru. We assessed feasibility and potential effectiveness, including within-person changes in self-reported adherence, psychosocial metrics (NIH Toolbox), and transition readiness (“Am I on TRAC” questionnaire, “Got Transition” checklist). From October 2019 to January 2020, we enrolled 30 adolescents (15–21 years). The nine-month intervention consisted of logistical, adherence and social support delivered by entry-level health workers and group sessions to improve health-related knowledge and skills and social support. In transition readiness, we observed within-person improvements relative to baseline. We also …

Impact Of Prolonged Isolation On Adolescents With Drug-Susceptible Tuberculosis In Lima, Peru: A Qualitative Study, Victoria Elena Rapoport, Elmer Altamirano, Liz Senador, Milagros Wong, Catherine B. Beckhorn, Julia Coit, Stephanie D. Roche, Leonid Lecca, Jerome T. Galea, Silvia S. Chiang

Social Work Faculty Publications

Objectives Patients with tuberculosis (TB) generally are instructed to isolate at the beginning of treatment in order to prevent disease transmission. The duration of isolation varies and may be prolonged (ie, lasting 1 month or more). Few studies have examined the impact of isolation during TB treatment on adolescents, who may be more vulnerable to its negative effects.

Methods This study took place from 2018 through 2019 in Lima, Peru, where the Ministry of Health mandates the exclusion of patients with TB from educational institutions for at least 2 months. Using semi-structured guides, we conducted individual in-depth interviews with adolescents …

Phip Variants Associated With Chung–Jansen Syndrome Disrupt Replication Fork Stability And Genome Integrity, Neysha Tirado-Class, Caitlin Hathaway, Wendy K. Chung, Huzefa Dungrawala

Molecular Biosciences Faculty Publications

Chung–Jansen syndrome (CJS) is a rare, autosomal dominant disorder characterized by developmental delay, intellectual disability/cognitive impairment, behavioral challenges, obesity, and dysmorphic features. CJS is associated with heterozygous variants in PHIP (Pleckstrin-Homology Interacting Protein), a gene that encodes one of several substrate receptors for Cullin4-RING (CRL4) E3 ubiquitin ligase complex. Full-length PHIP, also called DCAF14, was recently identified to function as a replication stress response protein. Herein, we report the identification of two PHIP missense variants identified by exome sequencing in unrelated individuals with CJS. The variants p.D488V and p.E963G occur in different functional elements of DCAF14-WD40 repeat domain and pleckstrin …

Sequence Properties Of An Intramolecular Interaction That Inhibits P53 Dna Binding, Emily Gregory, Gary W. Daughdrill

Molecular Biosciences Faculty Publications

An intramolecular interaction between the p53 transactivation and DNA binding domains inhibits DNA binding. To study this autoinhibition, we used a fragment of p53, referred to as ND WT, containing the N-terminal transactivation domains (TAD1 and TAD2), a proline rich region (PRR), and the DNA binding domain (DBD). We mutated acidic, nonpolar, and aromatic amino acids in TAD2 to disrupt the interaction with DBD and measured the effects on DNA binding affinity at different ionic strengths using fluorescence anisotropy. We observed a large increase in DNA binding affinity for the mutants consistent with reduced autoinhibition. The ΔΔG between DBD and …

Land Reversion And Zoonotic Spillover Risk, John E. Vinson, Nicole L. Gottdenker, Luis Fernando Chaves, Rajreni B. Kaul, Andrew M. Kramer, John M. Drake, Richard J. Hall

Integrative Biology Faculty and Staff Publications

Deforestation alters wildlife communities and modifies human–wildlife interactions, often increasing zoonotic spillover potential. When deforested land reverts to forest, species composition differences between primary and regenerating (secondary) forest could alter spillover risk trajectory. We develop a mathematical model of land-use change, where habitats differ in their relative spillover risk, to understand how land reversion influences spillover risk. We apply this framework to scenarios where spillover risk is higher in deforested land than mature forest, reflecting higher relative abundance of highly competent species and/or increased human–wildlife encounters, and where regenerating forest has either very low or high spillover risk. We find …

A Role For Community-Level Socioeconomic Indicators In Targeting Tuberculosis Screening Interventions, Meredith B. Brooks, Helen E. Jenkins, Daniela Puma, Christine Tzelios, Ana Karina Millones, Judith Jimenez, Jerome T. Galea, Leonid Lecca, Mercedes C. Becerra, Salmaan Keshavjee, Courtney M. Yuen

Social Work Faculty Publications

Tuberculosis screening programs commonly target areas with high case notification rates. However, this may exacerbate disparities by excluding areas that already face barriers to accessing diagnostic services. We compared historic case notification rates, demographic, and socioeconomic indicators as predictors of neighborhood-level tuberculosis screening yield during a mobile screening program in 74 neighborhoods in Lima, Peru. We used logistic regression and Classification and Regression Tree (CART) analysis to identify predictors of screening yield. During February 7, 2019–February 6, 2020, the program screened 29,619 people and diagnosed 147 tuberculosis cases. Historic case notification rate was not associated with screening yield in any …

The Effects Of Effluent Discharge Into The Santa Fé River, João Vito Bezerra Dragone

Undergraduate Journal of Mathematical Modeling: One + Two

The discharge of effluents into rivers is something that has occurred a lot throughout our history, rivers like the Mississippi River and the Tiete River (São Paulo, Brazil) have been targets for many years. Therefore, in this paper I choose to show, through hard data and some assumptions, the impact of sewage dumping in water bodies, in this case the Santa Fé River, Florida and the reason why we should avoid dumping these effluents into the rivers.

Monitoring Drug Concentration In Emergency Medicine, Andrew Woods

Undergraduate Journal of Mathematical Modeling: One + Two

The careful monitoring of a drug’s concentration in the body of a patient is of the utmost importance in modern medicine. Many of the lifesaving medications that are administered in an emergency medicine environment have a narrow window of efficacy. This effective concentration is in an ever-changing state, as the body processes and eliminates exogenous compounds that are introduced to maintain homeostasis. To ensure the proper treatment and/or management of ailments, special attention must be given to the concentration of a given drug in the body as time progresses. These changing concentrations can be evaluated and tracked using the mathematical …

Innovating During Times Of Disruption: A Project Management Framework For Transforming A Student Research Symposium To Serve Virtual Communities During Covid-19, Theresa G. Burress, Allison N. Symulevich

USF St. Petersburg Campus Faculty Publications

No abstract provided.

Randomized Controlled Trial Of A Prenatal Focused Coparenting Consultation For Unmarried African American Families: One-Year Infant And Family Outcomes, James P. Mchale, Carla Smith Stover, Chad Dube, Yana Sirotkin, Serina Lewis, Katherine Mckay

USF St. Petersburg Campus Faculty Publications

Despite a nonmarital birth rate of 70% for non-Hispanic Black women in the United States, there is a dearth of research on culturally grounded coparenting interventions for unmarried Black families with infants. Accordingly, this randomized controlled trial investigated one-year post-partum child and family outcomes of a novel modest dosage (6 session) Focused Coparenting Consultation (FCC) offered prenatally. One-hundred-thirty-eight families led by unmarried Black coparents were randomized to an intervention (N=70) or Treatment-As-Usual (TAU; control) condition (N=68). TAU families received navigational support in accessing existing community services for pregnant and parenting families. Intervention families also received TAU along with 6 dyadic …

Usft Copyright And Intellectual Property Services Assessment Fy22, Leetta Schmidt

All Assessment Data

No abstract provided.

Editorial: Emerging And Re-Emerging Viral Zoonoses, Naveen Kumar, Vladimir N. Uversky, Shailly Tomar, Kenneth S. M. Li, Keith Chappell, Susanna K. P. Lau

Molecular Medicine Faculty Publications

No abstract provided.

An Issue Of Concern: Unique Truncated Orf8 Protein Variants Of Sars-Cov-2, Sk. Sarif Hassan, Vaishnavi Kodakandla, Elrashdy M. Redwan, Kenneth Lundstrom, Pabitra Pal Choudhury, Tarek Mohamed El-Aziz, Kazuo Takayama, Ramesh Kandimalla, Amos Lal, Ángel Serrano-Aroca, Gajendra Kumar Azad, Alaa A.A. Aljabali, Giorgio Palù, Gaurav Chauhan, Parise Adadi, Murtaza Tambuwala, Adam M. Brufsky, Wagner Baetas-Da-Cruz, Debmalya Barh, Vasco Azevedo, Nikolas G. Bazan, Bruno Silva Andrade, Raner José Silva, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Open reading frame 8 (ORF8) shows one of the highest levels of variability among accessory proteins in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of Coronavirus Disease 2019 (COVID-19). It was previously reported that the ORF8 protein inhibits the presentation of viral antigens by the major histocompatibility complex class I (MHC-I), which interacts with host factors involved in pulmonary inflammation. The ORF8 protein assists SARS-CoV-2 in evading immunity and plays a role in SARS-CoV-2 replication. Among many contributing mutations, Q27STOP, a mutation in the ORF8 protein, defines the B.1.1.7 lineage of SARS-CoV-2, engendering the second wave of …

Effect Of Protein–Protein Interactions On Translational Diffusion Of Spheroidal Proteins, Aleksandra M. Kusova, Aleksandr E. Sitnitsky, Vladimir N. Uversky, Yuriy F. Zuev

Molecular Medicine Faculty Publications

One of the commonly accepted approaches to estimate protein–protein interactions (PPI) in aqueous solutions is the analysis of their translational diffusion. The present review article observes a phenomenological approach to analyze PPI effects via concentration dependencies of self- and collective translational diffusion coefficient for several spheroidal proteins derived from the pulsed field gradient NMR (PFG NMR) and dynamic light scattering (DLS), respectively. These proteins are rigid globular α-chymotrypsin (ChTr) and human serum albumin (HSA), and partly disordered α-casein (α-CN) and β-lactoglobulin (β-Lg). The PPI analysis enabled us to reveal the dominance of intermolecular repulsion at low ionic strength of solution …

An Ayurgenomics Approach: Prakriti-Based Drug Discovery And Development For Personalized Care, Zoufang Huang, Vivek P. Chavda, Rajashri Bezbaruah, Vladimir N. Uversky, Sucharitha Palagati, Aayushi B. Patel, Zhe-Sheng Chen

Molecular Medicine Faculty Publications

Originating in ancient India, Ayurveda is an alternative medicinal approach that provides substantial evidence for a theoretical-level analysis of all aspects of life. Unlike modern medicine, Ayurveda is based upon tridoshas (Vata, pitta, and Kapha) and Prakriti. On the other hand, the research of all the genes involved at the proteomics, metabolomics, and transcriptome levels are referred to as genomics. Geoclimatic regions (deshanupatini), familial characteristics (kulanupatini), and ethnicity (jatiprasakta) have all been shown to affect phenotypic variability. The combination of genomics with Ayurveda known as ayurgenomics provided new insights into tridosha that may pave the way for precision medicine (personalized …

Msh3 Homology And Potential Recombination Link To Sars-Cov-2 Furin Cleavage Site, Balamurali K. Ambati, Akhil Varshney, Kenneth Lundstrom, Giorgio Palù, Bruce D. Uhal, Vladimir N. Uversky, Adam M. Brufsky

Molecular Medicine Faculty Publications

Among numerous point mutation differences between the SARS-CoV-2 and the bat RaTG13 coronavirus, only the 12-nucleotide furin cleavage site (FCS) exceeds 3 nucleotides. A BLAST search revealed that a 19 nucleotide portion of the SARS-CoV-2 genome encompassing the furin cleavage site is a 100% complementary match to a codon-optimized proprietary sequence that is the reverse complement of the human mutS homolog (MSH3). The reverse complement sequence present in SARS-CoV-2 may occur randomly but other possibilities must be considered. Recombination in an intermediate host is an unlikely explanation. Single stranded RNA viruses such as SARS-CoV-2 utilize negative strand RNA templates in …

Bmi1 Silencing Induces Mitochondrial Dysfunction In Lung Epithelial Cells Exposed To Hyperoxia, Helena Hernández-Cuervo, Ramani Soundararajan, Sahebgowda Sidramagowda Patil, Mason T. Breitzig, Matthew Alleyn, Lakshmi Galam, Richard Lockey, Vladimir N. Uversky, Narasaiah Kolliputi

Molecular Medicine Faculty Publications

Acute Lung Injury (ALI), characterized by bilateral pulmonary infiltrates that restrict gas exchange, leads to respiratory failure. It is caused by an innate immune response with white blood cell infiltration of the lungs, release of cytokines, an increase in reactive oxygen species (ROS), oxidative stress, and changes in mitochondrial function. Mitochondrial alterations, changes in respiration, ATP production and the unbalancing fusion and fission processes are key events in ALI pathogenesis and increase mitophagy. Research indicates that BMI1 (B cell-specific Moloney murine leukemia virus integration site 1), a protein of the Polycomb repressive complex 1, is a cell cycle and survival …