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Raptor Nests As A Habitat For Invertebrates: A Review, James R. Philips, Daniel L. Dindal Jan 2024

Raptor Nests As A Habitat For Invertebrates: A Review, James R. Philips, Daniel L. Dindal

Journal of Raptor Research

No abstract provided.


Third Meeting Of The Raptor Research Foundation, Byron E. Harrell Jan 2024

Third Meeting Of The Raptor Research Foundation, Byron E. Harrell

Journal of Raptor Research

No abstract provided.


Cerulean Warbler (Setophaga Cerulea) Response To Changes In Forest Structure In Indiana., Kamal Islam, Jennifer Wagner, Ryan Dibala, Margaret Macneil, Kyle Kaminski, Lila (Prichard) Young Dec 2023

Cerulean Warbler (Setophaga Cerulea) Response To Changes In Forest Structure In Indiana., Kamal Islam, Jennifer Wagner, Ryan Dibala, Margaret Macneil, Kyle Kaminski, Lila (Prichard) Young

Ornitología Neotropical

No abstract provided.


Book Reviews—ReseñAs De Libros—Resenhas De Livros, John G. Blake Dec 2023

Book Reviews—ReseñAs De Libros—Resenhas De Livros, John G. Blake

Ornitología Neotropical

No abstract provided.


The Breeding Biology Of The Fork-Tailed Flycatcher (Tyrannus Savana) In Lowland Pine Savanna Habitats In Belize, Mario Teul, Victoria D. Piaskowski, Kari M. Williams Dec 2023

The Breeding Biology Of The Fork-Tailed Flycatcher (Tyrannus Savana) In Lowland Pine Savanna Habitats In Belize, Mario Teul, Victoria D. Piaskowski, Kari M. Williams

Ornitología Neotropical

No abstract provided.


Robin A Hughes, 1934-1991, Oscar Gonzalez M. Dec 2023

Robin A Hughes, 1934-1991, Oscar Gonzalez M.

Ornitología Neotropical

No abstract provided.


Automated Stereology For Determining Tissue Characteristics, Peter Randolph Mouton, Hady Ahmady Phoulady, Dmitry Goldgof, Lawrence O. Hall Oct 2023

Automated Stereology For Determining Tissue Characteristics, Peter Randolph Mouton, Hady Ahmady Phoulady, Dmitry Goldgof, Lawrence O. Hall

USF Patents

Systems and methods for automated stereology are provided. A method can include providing an imager for capturing a Z-stack of images of a three-dimensional (3D) object; constructing extended depth of field (EDF) images from the Z-stack of images; performing a segmentation method on the EDF images including estimating a Gaussian Mixture Model (GMM), performing morphological operations, performing watershed segmentation, constructing Voronoi diagrams and performing boundary smoothing; and determining one or more stereology parameters such as number of cells in a region.


Synthesis And Antibacterial Testing Of Novel Thiosulfonate Compounds, Lindsay I. Blume Jun 2022

Synthesis And Antibacterial Testing Of Novel Thiosulfonate Compounds, Lindsay I. Blume

USF Tampa Graduate Theses and Dissertations

Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Staphylococcus aureus (VRSA) are increasing concerns in the medical community. In addition to the threat of Staphylococcus aureus, the increase in number and severity of infections caused by other antibiotic-resistant bacteria is problematic to human health, particularly among the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter). The antibiotics like the penicillins and cephalosporins used commonly to treat MRSA, VRSA, and ESKAPE pathogens have continued to decline in the effectiveness. Our laboratory has developed a number of new families of anti-MRSA and anti-VRSA antibacterial compounds. In this thesis, …


Targeting The Side-Chain Convergence Of Α-Helical Hot Spots To Design Small-Molecule Mimetics Disrupting Protein-Protein Interaction, Zhen Wang Mar 2022

Targeting The Side-Chain Convergence Of Α-Helical Hot Spots To Design Small-Molecule Mimetics Disrupting Protein-Protein Interaction, Zhen Wang

USF Tampa Graduate Theses and Dissertations

α-Helix accounts for the largest class of protein secondary structures and plays a key role in mediating protein-protein interactions (PPIs). Small-molecule α-helix mimetics mimic the structural features of α-helical hot spots and offer a powerful tool to unravel complex signaling networks and mitigate aberrant PPIs. In this dissertation, the side-chain conformational convergence of α-helical hot spots was disclosed, and insights into the side-chain convergence were exploited to instruct the design of small-molecule α-helix mimetics. The first chapter of this dissertation provides an overview of the characteristics of α-helical hot spots and current strategies to design small-molecule α-helix mimetics. In chapter …


Exploring The Structure And Activity Of Metallo-Tetracyclines, Shahedul Islam Mar 2022

Exploring The Structure And Activity Of Metallo-Tetracyclines, Shahedul Islam

USF Tampa Graduate Theses and Dissertations

Copper as a key component of electron transport chain of eukaryotes is an essential transition metal ion. Copper homeostasis in mammals complex and tightly regulated. Its strong reactivity together with binding with biologically important chemicals can have important repercussions in human health and overall environment. Tetracycline as one of most abundantly used antibiotic of the world has become abundant in the environment as well. Herein in this dissertation we take the journey to explore the complexation of tetracycline with metals in the environment and the intricate interaction between copper and tetracycline by investigating their oxidative behavior once they are complexed. …


Postojna-Planina Cave System In Slovenia, A Hotspot Of Subterranean Biodiversity And A Cradle Of Speleobiology, Maja Zagmajster, Slavko Polak, Cene Fišer Jun 2021

Postojna-Planina Cave System In Slovenia, A Hotspot Of Subterranean Biodiversity And A Cradle Of Speleobiology, Maja Zagmajster, Slavko Polak, Cene Fišer

KIP Articles

The Postojna-Planina Cave System (PPCS) in central Slovenia is a globally exceptional site of subterranean biodiversity, comprised of many interconnected caves with cumulative passage length exceeding 34 km. Two rivers sink into the caves of the PPCS, called the Pivka and Rak, and join underground into Unica River, which emerges to the surface. The studies of fauna of PPCS began in the 19th century with the first scientific descriptions of specialized cave animals in the world, making it “the cradle of speleobiology”. Currently, the species list of PPCS contains 116 troglobiotic animal species belonging to eight phyla, confirming its status …


Lampenflora In A Show Cave In The Great Basin Is Distinct From Communities On Naturally Lit Rock Surfaces In Nearby Wild Caves, Jake Burgoyne, Robin Crepeau, Jacob Jensen, Hayden Smith, Gretchen Baker, Steven D. Leavitt May 2021

Lampenflora In A Show Cave In The Great Basin Is Distinct From Communities On Naturally Lit Rock Surfaces In Nearby Wild Caves, Jake Burgoyne, Robin Crepeau, Jacob Jensen, Hayden Smith, Gretchen Baker, Steven D. Leavitt

KIP Articles

In show caves, artificial lighting is intended to illuminate striking cave formations for visitors. However, artificial lighting also promotes the growth of novel and diverse biofilm communities, termed lampenflora, that obtain their energy from these artificial light sources. Lampenflora, which generally consist of cyanobacteria, algae, diatoms, and bryophytes, discolor formations and introduce novel ecological interactions in cave ecosystems. The source of lampenflora community members and patterns of diversity have generally been understudied mainly due to technological limitations. In this study, we investigate whether members of lampenflora communities in an iconic show cave—Lehman Caves—in Great Basin National Park (GRBA) in the …


Ojo Guareña: A Hotspot Of Subterranean Biodiversity In Spain, Ana Isabel Camacho, Carlos Puch May 2021

Ojo Guareña: A Hotspot Of Subterranean Biodiversity In Spain, Ana Isabel Camacho, Carlos Puch

KIP Articles

Ojo Guareña Natural Monument in Burgos (Spain) is an important and large karstic system. It consists of more than 110 km of surveyed galleries, and it has rich sources of organic material from the surface and permanent water circulation. It is the fourth largest cave system in the Iberian Peninsula, and one of the 10 largest in Europe. Ojo Guareña also ranks 23rd among the world’s largest caves. To date, only volcanic caves in the Canary Islands, in which between 28 and 38 subterranean species occur, are considered subterranean diversity hotspots in Spain. Here, we provide the first list of …


The Little Things That Count: Mapping Diversity Of West Florida’S Shelf, Nicole L. Seiden Mar 2021

The Little Things That Count: Mapping Diversity Of West Florida’S Shelf, Nicole L. Seiden

USF Tampa Graduate Theses and Dissertations

Biodiversity is essential to the ecosystem functions responsible for generating the multi-billion-dollar industries that the US relies on for food, storm mitigation, tourism and recreation, but is facing increasing natural and anthropogenic threats. High-resolution diversity data covering large spatial areas would enhance current ecology knowledge and better address conservation concerns in the Gulf of Mexico. However, acquiring and handling data of this nature is resource intensive and has not yet been established. In this study, high spatial resolution data was collected from gastropod living and death assemblages collected over 10 years from the West Florida Shelf (WFS). A multivariate regression …


Bone Microenvironmental Control Of Skeletal Malignancy, Chen Hao Lo Feb 2021

Bone Microenvironmental Control Of Skeletal Malignancy, Chen Hao Lo

USF Tampa Graduate Theses and Dissertations

Bone is a common site of metastasis for many solid malignancies. Bone-metastatic cancers pose a significant clinical problem worldwide and is among the main causes for cancer patient morbidity and mortality. Patients with advanced bone-metastatic diseases often present with either osteolytic or osteogenic bone diseases as their cancers progress. These bone pathologies are products of the cancer co-opting the local bone remodeling stroma to yield important growth nutrients and factors. Unfortunately, skeletal metastases remain incurable and are fatal. Identifying and understanding the causal multicellular and molecular interactions underlying skeletal malignancies can yield crucial ideas for targeting and inhibiting disease progression. …


Posttranslational Modification And Protein Disorder Regulate Protein-Protein Interactions And Dna Binding Specificity Of P53, Robin Levy Nov 2020

Posttranslational Modification And Protein Disorder Regulate Protein-Protein Interactions And Dna Binding Specificity Of P53, Robin Levy

USF Tampa Graduate Theses and Dissertations

p53 is an intrinsically disordered transcription factor that suppresses tumor development by arresting the cell cycle and promoting DNA repair. p53 deletions or mutations can lead to cancer due to the inability of cells to respond to stress. The protein levels and post-translational modification state of p53 changes in response to cellular stress like DNA damage. Previous studies have shown that p53 can undergo coupled folding and binding with the E3 ubiquitin ligase, Mdm2, and the histone deacetylase, p300. In normal cells, p53 is kept at a low level by Mdm2, which marks it with ubiquitin, targeting p53 for proteasome …


Spatial Contrasts In Hepatic And Biliary Pahs In Tilefish (Lopholatilus Chamaeleonticeps) Throughout The Gulf Of Mexico, With Comparison To The Northwest Atlantic, Susan M. Snyder, Jill A. Olin, Erin Pulster, Steven Murawski Mar 2020

Spatial Contrasts In Hepatic And Biliary Pahs In Tilefish (Lopholatilus Chamaeleonticeps) Throughout The Gulf Of Mexico, With Comparison To The Northwest Atlantic, Susan M. Snyder, Jill A. Olin, Erin Pulster, Steven Murawski

C-IMAGE Publications

A multinational demersal longline survey was conducted on the Gulf of Mexico continental shelf over the years 2015 and 2016 to generate a Gulf-wide baseline of polycyclic aromatic hydrocarbon (PAH) concentrations in demersal fishes. Tilefish (Lopholatilus chamaeleonticeps) were sampled in all regions of the Gulf of Mexico for biometrics, bile, and liver. Tilefish liver was also obtained from surveys in the northwest Atlantic Ocean for comparison. Liver tissues (n = 305) were analyzed for PAHs and select alkylated homologs using QuEChERS extractions and gas chromatography tandem mass spectrometry. Bile samples (n = 225) were analyzed for …


Drug Discovery Targeting The Disorder-To-Order Transition Regions Through The Conformational Diversity Mimicking And Statistical Analysis, Insung Na, Sungwoo Choi, Seung Han Son, Vladimir N. Uversky, Chul Geun Kim Jan 2020

Drug Discovery Targeting The Disorder-To-Order Transition Regions Through The Conformational Diversity Mimicking And Statistical Analysis, Insung Na, Sungwoo Choi, Seung Han Son, Vladimir N. Uversky, Chul Geun Kim

Molecular Medicine Faculty Publications

Intrinsically disordered proteins exist as highly dynamic conformational ensembles of diverse forms. However, the majority of virtual screening only focuses on proteins with defined structures. This means that computer-aided drug discovery is restricted. As a breakthrough, understanding the structural characteristics of intrinsically disordered proteins and its application can open the gate for unrestricted drug discovery. First, we segmented the target disorder-to-order transition region into a series of overlapping 20-amino-acid-long peptides. Folding prediction generated diverse conformations of these peptides. Next, we applied molecular docking, new evaluation score function, and statistical analysis. This approach successfully distinguished known compounds and their corresponding binding …


Evaluating Prevalence And Mortality Of External Injuries On Loggerhead (Caretta Caretta) And Green (Chelonia Mydas) Sea Turtles In Florida, Usa, Aleah Marie Ataman Jan 2020

Evaluating Prevalence And Mortality Of External Injuries On Loggerhead (Caretta Caretta) And Green (Chelonia Mydas) Sea Turtles In Florida, Usa, Aleah Marie Ataman

USF St. Petersburg campus Master's Theses (Graduate)

Anthropogenic threats, such as bycatch, boat strikes, and pollution, account for two to three times more sea turtle mortality events than natural causes. The goals of this study were to: (1) determine prevalence and cause of external traumatic injuries on nesting loggerhead sea turtles (Caretta caretta) in Juno Beach, Florida and (2) conduct an analysis of historical rehabilitation data from Florida Fish and Wildlife Conservation Commission (FWC) to calculate mortality of loggerhead and green (Chelonia mydas) turtles injured by boats. During the 2019 nesting season, 300 loggerheads were tagged and examined for external injuries. All injuries were categorized based on …


Usft Prog Proposal Cas Cell Bio Microbio Molecular Bio Cell Molecular Bio Bs 20190913, Usf Libraries Sep 2019

Usft Prog Proposal Cas Cell Bio Microbio Molecular Bio Cell Molecular Bio Bs 20190913, Usf Libraries

All Assessment Data

No abstract provided.


Usft Prog Proposal Cas Integrative Bio Marine Biology Bs 20190822, Usf Libraries Aug 2019

Usft Prog Proposal Cas Integrative Bio Marine Biology Bs 20190822, Usf Libraries

All Assessment Data

No abstract provided.


Methods Of Treating Epilepsy Using Neural Stem Cells That Express Nanog, Ssea-4, Oct-4, Mir-34b, Mir-34c And Mir-592, Cesario Venturina Borlongan, Carmelina Gemma, Fernando L. Vale Jul 2019

Methods Of Treating Epilepsy Using Neural Stem Cells That Express Nanog, Ssea-4, Oct-4, Mir-34b, Mir-34c And Mir-592, Cesario Venturina Borlongan, Carmelina Gemma, Fernando L. Vale

USF Patents

Provided herein is a method of diagnosing or prognosing an epilepsy or epilepsy-related disorder. Also provided herein is a method of treating an epilepsy or epilepsy-related disorder. Further provided are non-epileptic and epileptic neural stem cells and cell cultures.


The Potential Of Marine Microbes, Flora And Fauna In Drug Discovery, Santana Alexa Lavonia Thomas Apr 2019

The Potential Of Marine Microbes, Flora And Fauna In Drug Discovery, Santana Alexa Lavonia Thomas

USF Tampa Graduate Theses and Dissertations

Natural products are chemical compounds synthesized by a living organism. These compounds have been utilized by humans from ancient times to the present for their pharmacological and biological activities. Terrestrial organisms are considered a lucrative source of bioactive compounds and chemical diversity. Within the past 60 years, the marine environment has presented its potential as a validated source for structural diversity and biologically active compounds. Technology has given access from shallow waters down to the abyssal plane for exploration and investigation of the inhabitants. Marine organisms have displayed their benefits in the pharmaceutical industry with the approval of several marine-derived …


Spring Water Of An Alpine Karst Aquifer Is Dominated By A Taxonomically Stable But Discharge-Responsive Bacterial Community, Domenico Savio, Philipp Stadler, Georg H. Reischer, Katalin Demeter, Rita B. Linke, Alfred P. Blaschke, Robert L. Mach, Alexander K. T. Kirschner, Hermann Stadler, Andreas H. Farnleitner Feb 2019

Spring Water Of An Alpine Karst Aquifer Is Dominated By A Taxonomically Stable But Discharge-Responsive Bacterial Community, Domenico Savio, Philipp Stadler, Georg H. Reischer, Katalin Demeter, Rita B. Linke, Alfred P. Blaschke, Robert L. Mach, Alexander K. T. Kirschner, Hermann Stadler, Andreas H. Farnleitner

KIP Articles

No abstract provided.


Spring Water Of An Alpine Karst Aquifer Is Dominated By A Taxonomically Stable But Discharge-Responsive Bacterial Community, Domenico Savio, Philipp Stadler, Georg H. Reischer, Katalin Demeter, Rita B. Linke, Alfred P. Blaschke, Robert L. Mach, Alexander K. T. Kirschner, Hermann Stadler, Andreas H. Farnleitner Feb 2019

Spring Water Of An Alpine Karst Aquifer Is Dominated By A Taxonomically Stable But Discharge-Responsive Bacterial Community, Domenico Savio, Philipp Stadler, Georg H. Reischer, Katalin Demeter, Rita B. Linke, Alfred P. Blaschke, Robert L. Mach, Alexander K. T. Kirschner, Hermann Stadler, Andreas H. Farnleitner

KIP Articles

Alpine karst aquifers are important groundwater resources for the provision of drinking water all around the world. Yet, due to difficult accessibility and long-standing methodological limitations, the microbiology of these systems has long been understudied. The aim of the present study was to investigate the structure and dynamics of bacterial communities in spring water of an alpine limestone karst aquifer (LKAS2) under different hydrological conditions (base vs. event flow). The study was based on high-throughput 16S rRNA gene amplicon sequencing, study design and sample selection were guided by hydrology and pollution microbiology data. Spanning more than 27 months, our analyses …


Pah Exposure In Red Snapper (Lutjanus Campechanus) Collected At Natural And Artificial Reef Systems In The Northwestern Gulf Of Mexico, Tiffany Jane Nicholson Jan 2019

Pah Exposure In Red Snapper (Lutjanus Campechanus) Collected At Natural And Artificial Reef Systems In The Northwestern Gulf Of Mexico, Tiffany Jane Nicholson

USF St. Petersburg campus Master's Theses (Graduate)

Red Snapper are commonly recognized as an important fishery across the bordering states of the Gulf of Mexico (GoM) and are found in abundance around oil and gas platforms. A small, yet toxic and environmentally persistent component, of crude oil known as polycyclic aromatic hydrocarbons (PAHs), are released into Gulf waters through both anthropogenic (e.g., oil and gas activities) and natural (e.g., hydrocarbon seeps) sources. These pollutants are associated with a variety of negative health effects in fish including cardio-toxicity, reproductive and developmental impairment, and external skin lesions. The objectives of this study were to measure and to compare PAH …


P53 Phosphomimetics Preserve Transient Secondary Structure But Reduce Binding To Mdm2 And Mdmx, Robin Levy, Emily Gregory, Wade Borcherds, Gary W. Daughdrill Jan 2019

P53 Phosphomimetics Preserve Transient Secondary Structure But Reduce Binding To Mdm2 And Mdmx, Robin Levy, Emily Gregory, Wade Borcherds, Gary W. Daughdrill

Molecular Biosciences Faculty Publications

The disordered p53 transactivation domain (p53TAD) contains specific levels of transient helical secondary structure that are necessary for its binding to the negative regulators, mouse double minute 2 (Mdm2) and MdmX. The interactions of p53 with Mdm2 and MdmX are also modulated by posttranslational modifications (PTMs) of p53TAD including phosphorylation at S15, T18 and S20 that inhibits p53-Mdm2 binding. It is unclear whether the levels of transient secondary structure in p53TAD are changed by phosphorylation or other PTMs. We used phosphomimetic mutants to determine if adding a negative charge at positions 15 and 18 has any effect on the transient …


Validation Of A New Concept For Measuring Respirable Dusts, Xiao Liu Nov 2018

Validation Of A New Concept For Measuring Respirable Dusts, Xiao Liu

USF Tampa Graduate Theses and Dissertations

Sampling of airborne dust in industry is influenced by the potential health effects associated with human exposure. Health effects depend on mass concentration and particle size which influences the site of pulmonary deposition. Occupational diseases tend to be associated with dust deposition in specific regions of the respiratory tract. The ACGIH size selective TLVs are expressed in three forms: Inhalable Particulate Matter, Thoracic Particulate Matter, and Respirable Particulate Matter. In pneuomoconioses, the amount of dust deposited in the lungs can be estimated by sampling the respirable fraction. Dose-response relationships are derived by relating the health experience of workers to the …


Decision-Tree Based Meta-Strategy Improved Accuracy Of Disorder Prediction And Identified Novel Disordered Residues Inside Binding Motifs, Bi Zhao, Bin Xue Oct 2018

Decision-Tree Based Meta-Strategy Improved Accuracy Of Disorder Prediction And Identified Novel Disordered Residues Inside Binding Motifs, Bi Zhao, Bin Xue

Molecular Biosciences Faculty Publications

Using computational techniques to identify intrinsically disordered residues is practical and effective in biological studies. Therefore, designing novel high-accuracy strategies is always preferable when existing strategies have a lot of room for improvement. Among many possibilities, a meta-strategy that integrates the results of multiple individual predictors has been broadly used to improve the overall performance of predictors. Nonetheless, a simple and direct integration of individual predictors may not effectively improve the performance. In this project, dual-threshold two-step significance voting and neural networks were used to integrate the predictive results of four individual predictors, including: DisEMBL, IUPred, VSL2, and ESpritz. The …


Microscopic Fungi On Cadavers And Skeletons From Cave And Mine Environments, Alena Nováková, Alena Kubátová, František Sklenář Aug 2018

Microscopic Fungi On Cadavers And Skeletons From Cave And Mine Environments, Alena Nováková, Alena Kubátová, František Sklenář

KIP Articles

No abstract provided.