Digital Commons Network^™

Multiple Myeloma Risk Linked To Dna Damage Response Genes, Michael Conry, Irina Ostrovnaya, Yelena Kemel, Saloni Sinha, Linda B. Baughn, Brian Avery, Kylee Maclachlan, Victoria Groner, Lauren Banaszak, Aaron Norman, Nicholas J. Boddicker, Alyssa I. Clay-Gilmour Ph.D., Shaji Kumar, Ellen Kim, Sita Dandiker, Mitul Waghmare, Susan Slager, Douglas Sborov, Judy Garber, Elizabeth E. Brown, Michelle Hildebrandt, Et. Al.

Faculty Publications

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Background DNA damage response genes (DDRG), implicated in several cancers as both predisposing risk factors as well as biomarkers for aggressiveness, have not been fully explored in multiple myeloma (MM).

Methods Herein, we analyzed disease associations of pathogenic variations in nine putative candidate genes using 3 446 MM cases and 323 233 cancer-free controls.

Results Increased MM risk was found to be associated with inherited rare pathogenic mutations in TP53, ATM, CHEK2, KDM1A, and ARID1A, with an enrichment of these variants among individuals with early onset or family history of MM. Individuals with TP53 or ATM germline mutations are also …

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Asian Reference Values For Handgrip Strength, Gait Speed, Five-Times-Sit-To-Stand Test, Muscle Mass And Calf Circumference, Jozo Grgic, Siew Ling Tey, Dieu Thi Thu Huynh, Yen Ling Low, Zeljko Pedisic, Nina Schaller, Vanessa Kristina Wazny, Weilan Wang, Yasuhiko Saito, Ravindra P Rannan-Eliya, Hala Ghattas Ph.D., Monique Chaaya, Carlos Mendes De Leon, Preeti Gupta, Ecosse L Lamoureux, Mythily Subramaniam, Edimansyah Abdin, Rahul Malhotra, Angelique Chan, Bayasgalan Tumenbayar, Oyunbileg Luvsandavaajav, Bolormaa Enkhtuvshin, Norma Mansor, Halimah Awang, Andrea B Maier

Faculty Publications

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Background:Handgrip strength, gait speed, Five-Times-Sit-to-Stand Test (FTSST) performance, skeletal muscle mass and calf circumference are important health outcomes, particularly useful for diagnosing sarcopenia. The aim of this study was to establish reference (normative) values for handgrip strength, gait speed, FTSST performance, skeletal muscle mass and calf circumference by pooling individual participant data from national cohorts in Asia.

>Methods:We conducted a pooled analysis of individual participant data from 20 national cohorts representing 12 Asian countries (China, India, Indonesia, Israel, Japan, Lebanon, Malaysia, Mongolia, Philippines, Republic of Korea, Singapore and Sri Lanka). We included cohorts with data on at least …

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Flux Crystal Growth Of Potassium Lanthanide Double Vanadates With Lanthanide-Dependent Coordination Number Variance, Hunter B. Tisdale, Hans Conrad Zur Loye

Faculty Publications

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A series of potassium rare earth double vanadates is presented. Single crystals of double vanadates with stoichiometry K₃Ln(VO₄)₂ (Ln = La, Pr, Nd, and Sm) and crystallizing in the glaserite structure type were synthesized via a molten alkali chloride/fluoride flux reaction. Different structures were observed depending on the constituent rare earth: K₃La(VO₄)₂ crystallizes in an as-of-yet unreported modification of the typical glaserite structure in the space group P2₁/c, likely due to its larger ionic size that results in an increase in the lanthanide coordination number …

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Risk And Public Judgments On Police Pursuits: A Nationally Representative Conjoint Experiment, Scott M. Mourtgos, Ian T. Adams, Kyle Mclean, Geoffrey P. Alpert

Faculty Publications

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Police vehicle pursuits emphasize a central tension between law enforcement imperatives and public safety. While modern policies emphasize balancing apprehension needs against risks of continuation, little is known about whether public intuitions mirror this framework. We address this gap using a nationally representative conjoint experiment (N = 3,334) that varied eleven contextual factors across randomized pursuit scenarios. Respondents rated perceived risk, indicated whether pursuits should be terminated, and made forced-choice tradeoffs. Across all outcomes, high-risk situational factors (e.g., high speeds, adverse weather, heavy traffic, urban settings, etc.) increased perceived danger and termination support, while more serious underlying offenses, particularly …

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A Rosary Dipped In Blood, Collin Taylor

Athena: Undergraduate Research and Literary Journal

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A short story about a young adult male named Daniel who navigates the isolation he feels in a rural conservative small town. He seeks escape and liberation through books and education, as well as making his voice known regardless of the consequences.

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2025 - 2026 Faculty Senate Annual Report, University Of South Carolina

Faculty Senate

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The primary file includes the 2025 - 2026 Admissions Committee Report. Additional annual reports are attached.

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Stoichiometry-Controlled Surface Reconstructions In Epitaxial Abo3 Perovskites For Sustainable Energy Applications, Habib Rostaghi Chalaki, Ebenezer Seesi, Gene Yang, Mohammad El Loubani, Dongkyu Lee

Faculty Publications

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ABO₃ perovskite oxides are a versatile class of materials whose surfaces and interfaces play essential roles in sustainable energy technologies, including catalysis, solid oxide fuel and electrolysis cells, thermoelectrics, and energy-relevant oxide electronics. The interplay between point defects and surface reconstructions strongly affects interfacial stability, charge transport, and catalytic activity under operating conditions. This review summarizes recent progress in understanding how oxygen vacancies, cation nonstoichiometry, and electronic defects couple to atomic-scale surface rearrangements in representative perovskite systems. We first revisit Tasker’s classification of ionic surfaces and clarify how defect chemistry provides compensation mechanisms that stabilize otherwise polar or metastable …

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Navigating Racist Spaces Through Radical Self-Care: A Photovoice Exploration Of The Experiences Of Black Graduate Students, Laetitia Adelson, Cherese Fine, Dion Harry, Keneisha Harrington, Rebecca Lynn Morgan Ph.D., Tomiko Smalls, Jerad Green, Courtney Allen, Anuoluwapo Bankole, Robin Phelps-Ward

Faculty Publications

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This manuscript examines the impact of racist campus climates for Black graduate students at a predominantly white institution. Using a photovoice methodological design, this study illuminates students’ ability to thrive through radical self-care despite the many racist factors, incidents, and systems at the institution. The paper ends with recommendations for improving campus racial climate in graduate education.

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Deference To Prestige And Climate Policy, Ty’Teona Shannon, Jeffrey Sinn

Athena: Undergraduate Research and Literary Journal

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This research addresses the problem of resistance and support for climate mitigation policies. Studies have shown that personal values influence political orientations. However, it needs to be clarified what values motivate individuals to resist climate policies. Using hierarchical regression, we show that Social Dominance Orientation is a significant predictor of climate policy support and that Deference to Prestige does not have a strong relationship with climate policy support. Our findings are significant because they provide additional evidence that ideology and values relate to support for climate mitigation policies.

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Moving Forward Together For Cancer Recovery: Collaborative Guide For Researchers And Cancer Care Organizations, M. Madison Kindred, Karen E. Wickersham, Daneille E. Ostendorf, Bernardine M. Pinto

Faculty Publications

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No abstract provided.

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Understanding Addiction As A Disease: College Students’ Perspectives On Substance Use In The Covid-19 Era, Aditi Rudrashetty

Athena: Undergraduate Research and Literary Journal

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This research explores the neurological basis of addiction as a disease and how the exacerbation of external factors has contributed to negative perceptions of addiction. Specifically, it examines the COVID-19 pandemic and contemporary college student experiences as contextual factors influencing attitudes toward substance use disorders. Negative perceptions contribute to stigma, reduce help-seeking behavior, and influence policy responses, hindering effective support and recovery for individuals with substance use disorders. By examining these perceptions, this study contributes to understanding how addiction is conceptualized and potentially addressed in public health and policy contexts. Surveys and semi-structured interviews were conducted with college students to …

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Perceived Use Of Web-Based Videoconferencing For Social Connectedness Among Older Adults Living In Long-Term Care: Qualitative Study, Anna Garnett, Halyna Yurkiv, Denise M. Connelly, Richard Booth, Lorie Donelle Phd, Rn, Fcan, Faan

Publications

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Background:

The COVID-19 pandemic highlighted how restrictions on in-person interactions within long-term care homes (LTCHs) severely compromised social connectedness among older adults and their families. Post pandemic, despite policy changes supporting greater in-person family engagement, frequent outbreaks continue to disrupt face-to-face interactions, and factors such as geography, life circumstances, and health can constrain family members’ ability to make regular in-person visits. Research suggests that web-based videoconferencing technology (WVT) may be a practical solution to help older adults within LTCHs to maintain social connection in the absence of physical gathering. However, increased understanding of end user experience is lacking, and more …

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Developing A Best Practice Guideline For Clinical Practice In A Digital Health Environment: Systematic Reviews Based On The Grading Of Recommendations, Assessment, Development, And Evaluation Approach, Lauren Bailey, Lyndsay Howitt, Nafsin Nizum, Christine Buchanan, Maureen Charlebois, Jennifer Yoon, Rob Beleno, Michelle Beyn, Rebecca Bliss, Elizabeth Borycki, Margarita Cleghorne, Sandra Davidson, Lorie Donelle Phd, Rn, Fcan, Faan, Alexander Hamilton, Tsz Yee Ip, Margery Konan, Daile Moffat, Sanaz Riahi, Tiziana Rivera, Tammy Rooke, Vaishali Sengar, Steve Sottile, Meredith Whitehead, Vanessa Burkoski

Publications

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Background:

Digital health refers to the field of knowledge and practice associated with the development and use of digital technologies to improve clinical practice and health outcomes. Knowledge of digital health technology is becoming essential for all nurses and health providers.

Objective:

This study aims to present the results of the systematic reviews that were used to inform the recommendations in a best practice guideline (BPG) following the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) approach. Reviews focused on digital health education for nurses and health providers, peer champion models, and the use of predictive analytics in digital health …

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Mental And Physical Humanlikeness In Artificial Intelligence Influencers: Effects On Humanness, Eeriness, And Consumer Responses, Terry Kim Ph.D., Hyunjoo Im

Faculty Publications

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Artificial intelligence (AI) influencers, nonhuman characters powered by AI, have garnered a significant following on social media in recent years. Through two between-subjects online experiments (n = 957), this study investigates the impact of AI influencers' appearance realism and self-disclosure on consumer perceptions (humanness and eeriness) and their downstream responses (intention to self-disclose, intention to follow the advice, and brand attitude). Drawing from anthropomorphism and theory of mind, this study emphasizes the distinction of two dimensions of AI influencers' humanlikeness (physical and mental) which differently affect the humanness and eeriness of the AI influencer. Results indicate that the AI …

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Academic Unit Guide To Internships For Academic Credit, Lara Lomicka Anderson, Karen Edwards

Reports

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This guide establishes university-wide best practices for internships completed for academic credit (ACAF 2.03(H)). It is intended to support faculty, internship directors, and academic units in designing and supervising internships that are academically rigorous, safe for students, and compliant with accreditation and institutional policies. At the University of South Carolina, some academic units require internship credit as part of the degree, while many others offer internship courses that allow students to gain professional experience, apply their academic learning, and develop valuable professional networks. For internships that are not completed for academic credit, (e.g., Carolina Internship Program, J-1 …

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Factors Influencing Senior Practicum Readiness For Nursing Practice: A Descriptive Correlational Study, Beth Nease Phd, Dnp, Rn, Ne-Bc, Cynthia F. Corbett Phd, Rn, Faan, Stephanie Armstrong Phd, Msn, Rn, Kesheng Wang Phd, Ma, Bs, Kathy Casey, Kong Chen

Faculty Publications

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Background:

This study investigated the influence of belongingness, self-efficacy, and clinical learning support on readiness for nursing practice and explored the role of demographic factors and nursing program differences.

Method:

A quantitative, descriptive approach was used to explore undergraduate prelicensure senior nursing students' perceptions across the United States.

Results:

Descriptive statistics, Pearson correlation, and multiple linear regression demonstrated students in traditional Bachelor of Science in Nursing programs reported significantly higher scores across all domains compared with those in associate degree programs (p < .01). Similarly, students in programs with ≤400 clinical hours and those assigned only one preceptor scored significantly higher on all measures (p < .01 and p < .05, respectively). Regression analysis indicated self-efficacy and learning support explained 47.9% of the variance in practice readiness (p < .05).

Conclusion:

These findings share how clinical experiences shape students' readiness for nursing practice. Recommendations …

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Cisheterosexism In Lgbtqia+ Health Resource Guides, Vanessa Kitzie, Olivia Reed, Amirezza Kalantari

Faculty Publications

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Cisheterosexism in LGBTQIA+ Health Resource Guides Vanessa Kitzie, Amirezza Kalantari, Olivia Reed University of South Carolina, School of Information Science [email protected] Limited healthcare resources lead many LGBTQIA+ people to peer networks, often accessed via search engines to find community-created health resource websites [1–3]. Academic library guides benefit privileged LGBTQIA+ identities [4], but little is known about community guides, which may reinforce cisheterosexist narratives, causing stigma and stress [5, 6]. This study addresses this gap by scraping Google results for LGBTQIA+ health resources across US states, examining how cisheterosexism shapes health topics, geography, and representation of LGBTQIA+ populations. We hypothesize that …

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Protecting The Debtor Across The Atlantic: A Comparative Analysis Of The United States And European Union Regulatory Frameworks Against Debt Collection Abuse And Harassment, Terin Michelle Tyson

South Carolina Journal of International Law and Business

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Consumer debt is a long-standing global phenomenon, yet the regulation of debt collection practices remains fragmented across international borders. This lack of uniform standards leaves consumers vulnerable to debt collectors who exploit weak legal frameworks, resorting to abusive, harassing, and deceptive tactics to pressure repayment. Such practices not only undermine consumer trust in the financial services industry but also prove self-defeating; aggressive collection methods can destabilize a consumer’s financial footing and daily livelihood, ultimately impairing their capacity to repay.

This article provides a comparative evaluation of consumer protections against abusive and harassing debt collection practices in the United States and …

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Dyno : Dynamic Neurosymbolic Orchestrator For Multi-Agent Systems, Ritvik Garimella, Chathurangi Shyalika, Renjith Prasad, Amit Sheth

Publications

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Large Language Model (LLM)-based multi-agent systems (LaMAS) represent an emerging paradigm for tackling complex, multi-step reasoning and decision-making problems. As these systems scale, orchestration, which is the ability to coordinate, manage, and evaluate the interactions among diverse agents, becomes central to their success. While recent orchestrators such as AgentFlow have demonstrated promise in managing communication and task delegation, they remain limited in their ability to understand task semantics, coordinate heterogeneous agent types (e.g., reactive vs. cognitive), and adaptively align outputs with human-defined goals. In this position paper, we introduce the DYNO (Dynamic Neurosymbolic Orchestrator), a system developed as part of …

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Co-Developing Strategies For Leprosy Management In Malaysia: A Transdisciplinary Research Approach Involving Individuals Affected By Leprosy And Other Stakeholders, Norana Abdul Rahman, Vaikunthan Rajaratnam, Ruth Mh Peters, Marjolein Bm Zweekhorst, Pamela Wright Phd, Ms, Med, Rn, Cen, Karen Morgan, Mohamed Rusli Abdullah

Publications

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Despite Malaysia's low leprosy prevalence, new cases continue to emerge in rural and Indigenous communities. National strategies often prioritise elimination and surveillance, while overlooking the needs and challenges of individuals affected by leprosy and those managing their care. This study employed a transdisciplinary research approach, guided by the Dialogue Model, to co-develop context-specific strategies to improve the lives of those affected through participatory engagement with both groups. Conducted across three high-burden states in Peninsular Malaysia, the research involved a desk review and stakeholder mapping, followed by 40 in-depth interviews with affected individuals and other stakeholders. These were complemented by a …

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Nurses' Implicit Bias Toward Older Adults: A Mid-Range Nursing Theory, Jennifer T. May Phd, Rn, Anp-Bc, Hanne Dolan, Jessica G. Rainbow

Publications

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This article describes the development of the Nurses' Implicit Bias Toward Older Adults Mid-Range Nursing Theory, which explains how biased care arises and affects older adults. Drawing from Pepper's contextual-development worldview, Parse's Humanbecoming Paradigm, and an emancipatory perspective, the theory integrates implicit social cognition to explain how nurses' backgrounds and unconscious processes influence clinical practice. Key "mitigation points" are identified for targeted interventions to address bias. This framework provides a foundation for future research on implicit bias in nursing, with implications for equitable health care delivery and improved older adult patient outcomes, supporting the advancement of nursing science and professional …

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Energetics And Kinetics Of Alkali Ion Exchange In Analcime, Jinyi Liu, An T. Ta, R. Seaton Ullberg, Jean Wilfried Hounfodji, Michael Badawi, Hans Conrad Zur Loye, Simon R. Phillpot

Faculty Publications

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We employ density functional theory calculations to investigate the energetics and diffusion mechanisms of alkali metal ions (Na⁺, K⁺, Rb⁺, and Cs⁺) within the analcime framework. While Na⁺preferentially adsorbs at the center of the 8-member ring, DFT calculations show that larger ions, such as Cs⁺, occupy the center of the cage due to steric constraints. The computed exchange energies indicate that exchange of Na⁺by Cs⁺is thermodynamically favorable. Migration energy barriers, determined using the climbing image nudged elastic band method, show that Na⁺is …

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A Multi-Case Study Exploring Ncaa Division I Athletic Departments’ Mental Health Culture, Kim Tolentino, Dana K. Voelker, Brent Oja, Sofia España Pérez, Sam Zizzi

Journal of Issues in Intercollegiate Athletics

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Mental health and psychological well-being continue to be significant areas of concern for collegiate student-athletes. Researchers have identified the perceived barriers preventing student-athletes from using mental health services which include lack of knowledge, limited access, and perceived negative stigma (e.g., Harris & Maher, 2023; Yoon & Petrie, 2023). Organizational culture, loosely defined as a group’s accumulated shared learning (Schein & Schein, 2017), plays an important role in guiding the behaviors of its members. Developing a positive athletic department culture around mental health can, in turn, be beneficial to increasing student-athletes’ help-seeking behaviors. The purpose of this study was to explore …

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College Athlete Mental Health: Identifying Sources Of Support In Collegiate Athletics, Levone Lee, Lauren Beasley, Kaylee A. Palomino, Patricia M. Kelshaw, Joycelyn Kennedy, Deborah Chanan, Elinah Russell, Tarkington J. Newman

Journal of Issues in Intercollegiate Athletics

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Despite having access to resources and services, college athletes continue to encounter negative mental health experiences and outcomes. Prior research has begun to identify key sources of social support within collegiate athletics, including teammates and athletic trainers. However, there is limited understanding of with whom college athletes feel most comfortable discussing their mental health. The current study aims to identify preferred sources of social support when athletes wish to discuss their mental health and, in turn, examine differences in preference among unique college athlete populations. In total, 247 college athletes participated in the study, representing eight universities within an NCAA …

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Mechanistic Roles And Design Criteria For Catalysts In Lithium–Sulfur Batteries, Saheed Lateef, Golareh Jalilvand

Faculty Publications

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Catalysis is widely explored in lithium–sulfur (Li–S) batteries to address challenges related to limited capacity and cycle durability. Despite extensive research, catalyst development has often focused on materials without a clear understanding of the mechanistic landscape underlying the complex, multi-step, multi-electron sulfur redox pathway. In fact, our understanding of the thermodynamic, kinetic, and mass transport framework in Li–S systems is still evolving, particularly with respect to the reaction pathways during charge and discharge, and the dynamic evolution of materials in both liquid and solid phases. These evolving insights may fundamentally shift the requirements for catalyst design and future research priorities. …

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And Then There Were Two: Navigating Library Services Through Institutional Change, Joni Addis

South Carolina Libraries

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Based on an SCLA conference presentation, this article reflects on one small academic library’s journey through university-wide rightsizing and the impact it had on library services. The loss of positions necessitated across-the-board changes in the division of responsibilities and library operations. In the current climate of higher education in the United States, library staff at other institutions should prepare now for possible staffing challenges in the future. Practical takeaways learned through navigating institutional change are discussed, along with an action plan for library administrators and leaders.

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Tennyson & Contemporary Science: Herschel’S Preliminary Discourse, A Book That Got Away, Patrick Scott

Faculty Publications

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Discusses the rediscovery, provenance, and authenticity of the copy of John Herschel's Preliminary Discourse on the Study of Natural Philosophy (1831), with an ownership inscription by Tennyson dated 1843, and marginal markings on multiple pages, that was previously only known from a brief catalogue description for a 1924 auction.

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Changing Minds, Changing Behavior The Role Of Cognitive-Behavioral Therapy In Addressing Intimate Partner Violence, Natalie Freeman

Graduate Student Thesis

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Intervention programs for intimate partner violence abusers are designed to address and mitigate violent behaviors and promote healthier relationships to reduce recidivism. This paper examines various intervention programs and their strategies, including cognitive-behavioral therapy (CBT), group therapy, and educational programs, along with their theoretical foundations and effectiveness. Cognitive-behavioral therapy focuses on altering thought patterns that contribute to abusive actions, demonstrating effectiveness in reducing violent behaviors and promoting emotional regulation. This study utilized a qualitative design in collaboration with Anger Management of the Upstate, where participants in a CBT-based intimate partner violence intervention program completed an anonymous Qualtrics survey exploring their …

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December 3, 2025 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

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No abstract provided.

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An Arendtian Politics Of Life, Kamryn M. Carter

Senior Theses

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As defined in The History of Sexuality (1978), Michel Foucault’s concept of biopolitics focused on a specifically modern phenomenon in which biological processes are used to regulate populations. This concept has been influential in modern analyses of the state such as that of Giorgio Agamben, who sought to both correct and complete biopolitics with his concept of homo sacer as part of his analysis of the concentration camp. This thesis brings the theory of biopolitics into conversation with Hannah Arendt’s politics of life. It seeks to determine the degree to which biopolitics — as seen in the work of Michel …

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