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Gut Microbiome Dynamics In Heart Failure And The Therapeutic Potential Of Nmeg-Cgrp, Kamryn Michael Gleason

Theses and Dissertations

Heart failure (HF) is increasingly recognized as a multisystem disease often linked to gut dysbiosis; however, its specific effects on gut microbial composition remain poorly understood. This study examined long-term changes in the gut microbiome in a murine HF model induced by transverse aortic constriction (TAC) and evaluated the effects of NMEG-CGRP. TAC mimics pressure overload-induced cardiac dysfunction, replicating key features of HF. CGRP, a neuropeptide with vasodilatory and cardioprotective effects, shows potential as a therapy for HF but is limited by rapid degradation. A stabilized analog, NMEG-CGRP, was used to assess its impact on cardiac and gastrointestinal health. Mice …

Parental Attitudes And Expectations Regarding Piano Study For Their Children With Autism Spectrum Disorder, Lin Zhong

Theses and Dissertations

This study investigates parental attitudes and expectations regarding piano study for children with Autism Spectrum Disorder. Although music has been recognized for its therapeutic and educational benefits among individuals with ASD, research examining these outcomes from the perspective of parents has been limited. This study focuses on in-depth interviews with nine parents of children with ASD enrolled in the Carolina LifeSong Initiative, a specialized piano program serving students with diverse developmental disorders.

The interviews explored parents’ motivations for initiating piano study, expectations for both musical and non-musical outcomes, and observations of their children’s growth and challenges through music. Parents reported …

Spectral Modeling Of Electromagnetic Radiation From Power Converters, Regan A. Varner

Theses and Dissertations

Switching power converters are increasingly utilized in contemporary electronics. They are becoming more compact and operate at higher frequencies, which contributes to radiated electromagnetic interference (EMI). This EMI is important to quantify for electromagnetic compatibility of the converters with other nearby systems. In this thesis, analytical models have been developed for both ideal and non-ideal switching waveforms, employing piecewise functions to describe time-domain waveforms, with their corresponding frequency spectra derived and compared to empirical spectra. The results demonstrate that the comparisons with measured frequency data exhibit agreement with the analytical models up to approximately 25 MHz. Additionally, our analysis indicates …

Examining Stress And Anxiety Levels Among Undergraduate Music Majors At The University Of South Carolina, Elise F. Halbig

Senior Theses

The purpose of this study was to examine the stress and anxiety levels among undergraduate music majors at the University of South Carolina (USC) and identify potential stressors that might be unique or more prevalent among that specific population. To evaluate this, a questionnaire consisting of 42 questions was administered to participants. Most of the questions were carefully developed by the researcher; however, the Perceived Stress Scale (Cohen et al, 1983) was used to examine participants' stress levels, and 13 selected questions from the Burns Anxiety Inventory (Burns, 1989) were used to examine their anxiety levels. A total of 45 …

Introduction: Dreaming The Daily Darg, Corey Gibson

Studies in Scottish Literature

Describes the scope of the Carnegie Trust -funded project on Working Lives in Scottish Writing since 1918, discusses the topics and theoretical perspectives explored in the research phase, noting both change and continuity from the treatment dominant in early and mid-20th century Scottish literary studies, and introduces the essays in this special issue and their contributions to the wider project theme.

Scottish Workers’ Stories Of Life And Labour During Covid-19 From The Workers’ Stories Project, Hailey Maxwell, Ruth Gilbert, Suki Sangha, Ewan Gibbs

Studies in Scottish Literature

This article explores how Scottish workers narrated the impact of the COVID-19 pandemic on their life and work, by analysing 55 fifty-five submissions to the Workers' Stories Project. Between 2020 and 2022, the project creative reflections on the pandemic from workers across Scotland, drawing on the tradition of workers' inquiry and workers' education that encouraged critical reflection and the embrace of worker creativity. Submissions were overwhelmingly literary in form, primarily short prose supplemented by poetry, with three key themes emerging: intimacy and alienation; insecurity and status; and a slower living pace. Cumulatively, the stories underline how COVID-19 magnified workplace injustices …

Teaching While Stressed: How Mental Support Is Impacting The Teaching Experience In South Carolina, Olivia Striedl

Senior Theses

Teacher shortages are a widespread issue within both the United States and South Carolina. One cause of high numbers of teachers leaving their positions is low job-satisfaction and high stress levels. In this study of teacher mental health in South Carolina, eight teachers were interviewed regarding their experience with job-related stress and support offered to them. The interviews revealed that teachers experience high levels of stress, with many interviewees having stressors in common. Many participants had at least one experience in which stressors pushed them to leave or almost leave their position, showing the importance of mental health when considering …

The Moderating Effects Of Community Involvement On The Association Between Witnessed Community Violence And Mental Health Outcomes Among Black Adolescents, Curtisha Tamara Shacklewood

Theses and Dissertations

Black youth and adolescents are at a disproportionately high risk for experiencing community violence exposure (CVE) and the potential influence it may have on psychological functioning. Research posits that Black youth who experience community violence are at a significantly higher risk of experiencing elevated internalizing symptoms (e.g., depression) and externalizing symptoms (e.g., delinquency). Previous research has utilized the ecological model to investigate interpersonal protective factors that potentially buffer the effects of CVE, including parental support and family characteristics. However, there is little research that explores community-level factors, such as community activities (e.g., youth activities and parental perception of collective efficacy) …

Developing A Dynamic Bilingual Space In An Early Childhood Korean Heritage Language Classroom Through Multimodal Translanguaging Pedagogy, Kyungjin Hwang

Theses and Dissertations

Drawing on translanguaging theory and multimodal literacy, this dissertation examines how a multimodal translanguaging pedagogy can create a dynamic bilingual space in a Korean heritage language classroom in the southeastern United States. Using a teacher-research design and thematic analysis of classroom video recordings and student artifacts, the study explored ten instructional modules with Korean-American children aged five to six. It first identified the core components of the pedagogy, its framework, curriculum content, and teacher strategies, and then analyzed how children flexibly used Korean and English across modes such as speaking, writing, and drawing. Findings revealed diverse translanguaging forms and functions. …

The Impact Of Project-Based Learning On Future First Generation College Students’ Oral Communication Skills, Presentation Skills, Confidence Levels, And College And Career Readiness, Mandana Marashi

Theses and Dissertations

The purpose of this action research was to evaluate the impact of a project-based learning innovation course on high school students’ oral communication, presentation skills, confidence levels, and college and career readiness in a college and career readiness program housed at a university in the Mid-Atlantic region. Effective oral communication and presentation skills have been continuously emphasized by national organizations and employers to be critical skills for success in students’ academic and professional lives. However, teaching oral communication and presentation skills to high school students has been neglected, which has negatively affected students’ college and career readiness, particularly for students …

Unveiling Caulocovert: Conserved Phage And Gene Transfer Agent In Caulobacter, Talia Neco

Theses and Dissertations

Bacteriophage play an important role in bacterial evolution, population control, and horizontal gene transfer within microbial ecosystems. This study focuses on the discovery and characterization of Caulocovert, an active bacteriophage identified in multiple Caulobacter strains. Using genome annotation tools such as Artemis and Mauve, we identified multiple key phage genes, including the major capsid protein, head-tail connector, portal protein, and major tail protein. These phage genes are present in CB13 and several other strains, such as C. vibriodies CB15 and CB2, C. segnis CBR1, Caulobacter sp. FWC26, and the distantly related Caulobacter sp. D5 strain. The location of these genes …

Influence Of School Climate On Comprehensive School Behavioral Health Effectiveness, Halle Rose Singer

Theses and Dissertations

Youth are experiencing a sharp rise in mental health concerns, which have reached critical levels. Schools have emerged as a key setting for delivering mental health services due to their accessibility, familiarity, and capacity to reach diverse populations. Comprehensive School Behavioral Health (CSBH) systems offer a multi-tiered, evidence-based framework for supporting the mental health of all students. However, the success of CSBH interventions varies across schools presumably indicating that systemic or school level factors, like school climate, may influence youth mental health outcomes. In this study, I investigate how school-level factors, specifically student-perceived school climate, influence the mental health outcomes …

Investigating The Influence Of Instructional Strategies On The Development Of Procedural And Conceptual Knowledge In Advanced Algebra Ii Students, Maura Frances Yinger

Theses and Dissertations

This mixed-methods action research study investigated the influence of instructional strategies shown to improve students’ procedural and conceptual understanding in a rational expressions and equations unit in Advanced Algebra II. The instructional strategies used in the study include comparing, self-explaining, and exploring before instruction. The students (N=27) completed a pre-test and a post-test, both of which were followed by questions asking students to justify their responses on two questions. All students also responded to six digital self-explanation journal prompts. Randomly selected students were placed into three homogenous groups to participate in performance task observations. Analysis of the data …

​​​Creating A Resident And Fellow Scholarly Activity Tracking Tool In A Large Academic Health System: A Dissertation In Practice​, Elyse Anne Wieszczecinski

Theses and Dissertations

Documenting and reviewing resident and fellow scholarly activity within a sponsoring institution can be a laborious task. With multiple lines of information coming from a wide variety of sources, this problem of practice implemented the Information Systems Success Model to help develop a database by which this information can be collected in a way that is efficient while maintaining the need for a user-friendly product. While other healthcare entities have also incorporated this model into their scholarly activity collection, these are still individual needs of the sponsoring institution and its constituents to consider when adapting the strategy. Using an improvement …

Journey To Proficiency: The Impact Of Explicit Problem-Solving Instruction In A Fifth-Grade Math Classroom, Brittany J. Terry

Theses and Dissertations

This action research study examined the impact of explicit problem-solving instruction on fifth-grade students’ mathematics proficiency and attitudes across skill levels. At the outset, students relied on rote procedures rather than conceptual reasoning, limiting their ability to apply skills in new contexts or understand why procedures work. Grounded in constructivist and sociocultural learning theories, the study aimed to move students beyond procedural fluency through explicit instruction of problem-solving strategies, modeling, guided practice, collaboration, and reflection. Over 8 weeks, 32 students participated in daily lessons. Findings from pre–post assessments, interviews, and portfolios indicate that explicit problem-solving instruction supported measurable growth in …

Journey Toward Collective Efficacy: ​The Impact Of Lesson Study In A Professional Learning Community, Julia Rose Pabst

Theses and Dissertations

This mixed methods action research study investigated the impact of a lesson study protocol on elementary teachers’ confidence through the implementation of the Three Read Close Reading Protocol (3RCRP), a research-based reading comprehension strategy. This study, grounded in Bandura’s Social Cognitive Theory, explored how collaborative and practice-based professional learning could bridge the gap between pedagogical knowledge and classroom practice to enhance teacher self-efficacy. The primary research questions focused on how participation in a lesson study influenced teachers’ self-efficacy and which aspects of the protocol were perceived as most influential. Four participants and one participant-observer engaged in a series of Professional …

Developing A Comprehensive Schoolwide Discipline Plan In Title 1 Southern Schools, Rose Clark Kebe

Theses and Dissertations

This qualitative case study explored how teachers in Title I schools across the southern United States perceived and experienced school discipline practices. The study addressed the problem of inconsistent implementation of restorative and preventive frameworks, which has contributed to inequitable outcomes, teacher frustration, and lost instructional time. Although initiatives such as Positive Behavioral Interventions and Supports (PBIS) are mandated across many districts, inconsistent use and limited fidelity have restricted their effectiveness in improving equitable discipline and school climate.

The purpose of the study was to examine teacher perspectives to inform the development of a culturally responsive, schoolwide behavioral system grounded …

Influence Of Channel Geometry And Inflow Hydrograph On Hydraulics And Air Volume Around Shafts Of A Stormwater Main, Lylie Vindie Wilkie

Theses and Dissertations

Stormwater management in urban areas is complex, in part because of difficulties related to modeling water flowing in closed conduits, as well as to controlling odor, noise, and pipe corrosion. This thesis summarizes the main findings of a study on how changes in inflow discharge and the geometry of a stormwater main may affect water flow, and how changes in water depth impact air volume and pressure around an air shaft. The study is conducted using CHAN, a one-dimensional model that simulates both flow hydraulics in mains and associated changes in air volume and pressure around air shafts. Main difference …

The Role Of Fibroblast Activation Protein On Left Ventricular Growth And Extracellular Matrix Remodeling As A Function Of Age And Pressure Overload, Amelia Marie Churillo

Theses and Dissertations

Fibroblast activation protein (FAP) is abundantly expressed in cancer associated fibroblasts and contributes to extracellular matrix (ECM) remodeling. Recent studies using imaging techniques have identified increased levels of FAP in the left ventricle (LV) of patients identified as at risk for developing heart failure. However, the role of FAP in regulated LV myocardial structure and function remains unclear. This project tested two hypotheses: First, genetic ablation of FAP would modify LV structure and function and be more pronounced with aging. Second, genetic ablation of FAP would modify LV structure and function with LV pressure overload (LVPO) accompanied by ECM remodeling.

Combating Obesity: Creating A Comprehensive Wellness Plan For Uninsured & Low-Income Populations, Kayla C. Berrios

Doctor of Nursing Practice Scholarly Projects

Aim: The aim of this project was to research the specific barriers encountered by obese patients that are low-income and uninsured. The goal of this data collection was to inform the stakeholders involved in creating a comprehensive wellness plan for obese patients.

Background: The staff at Good Neighbor Clinic have struggled to support their support their obese patients with weight reduction. Many of the ailments that patients seek care for correlate to their obesity. Health promotion in this community clinic needs a more comprehensive program to support patients during their weight loss experience, providing support and resources to allow for …

Improving The Discussion Of Suicide Prevention: A Quality Improvement Project, Chelsea Reynolds, Alyssa Zeitouni, Kathryn Stephenson

Clinical Practice in Athletic Training

Suicide is currently the second leading cause of death among adolescents in the United States and the third leading cause of death in this age group worldwide.1,2 Suicide prevention is understandably a growing focus in pediatrics. Currently, at the Children’s Hospital Outpatient Clinic, that is staffed by pediatric resident physicians, suicidal ideation is screened for using a PHQ-9 screen. However, at the time this study was initiated and completed, the TEEN screen was utilized. After the screening is performed, regardless of type, it is up to the provider to address these findings in a safe and effective manner. The goal …

Assessing Inclusion Within Naaee Affiliate Ee Associations And Where To Go From Here, Connor Chilton

Theses and Dissertations

Environmental Education (EE) has a history that has been typically defined by traditionally dominant identities (White, male, able-bodied, etc.). The North American Association for Environmental Education (NAAEE) offers a unique position as frontrunners for the field of EE and have the duty to provide an inclusive-minded education for and about the environments throughout the world. Through NAAEE’s affiliate network within the United States, this paper details a glimpse into the work towards inclusion by surveying its leadership position holders about the broad subject and several interconnections of inclusion. Upon completion of the survey, participants who opted to participate in a …

Examining The Effects Of Firearm Lethality And Aggressors’ Intentions To Kill On Injurious Firearm Violence At American Schools: A Research Note, Brent R. Klein, Cory Schnell, Steven M. Chermak, Joshua D. Freilich

Faculty Publications

This study examined firearm lethality and aggressors’ lethal intent on injurious fatal and nonfatal school shootings using data from The American School Shooting Study, which covers 329 school shootings in the United States from 1990 to 2016. We developed a new multidimensional construct for measuring shooters’ determination to kill and examined firearm characteristics while considering confounding factors. We identified 11 distinct categories of shooters’ intent, with most showing a strong desire to kill. Both intent and weapon lethality significantly impacted school shooting homicides. Overall, we recommend that prevention and theoretical models should address both factors.

Effect Of Vitamin D Supplementation During Pregnancy And Lactation On The Development Of Infants Born To Tanzanian Women Living With Hiv: A Secondary Analysis Of A Randomised Controlled Trial, Temiwunmi Shobanke, Alfa Muhihi, Nandita Perumal Phd, Nzovu Ulenga, Fadhlun M. Alwy Al-Beity, Christopher P. Duggan, Wafaie W. Fawzi, Karim P. Manji, Christopher R. Sudfeld

Faculty Publications

Background Infants born to pregnant women living with HIV (WLHIV) are at greater risk for morbidity and mortality and may also have poorer developmental outcomes as compared with infants who are not exposed to HIV. Nutrition interventions in pregnancy may affect developmental outcomes.

Objectives This study evaluated the effect of maternal vitamin D supplementation on infant development outcomes.

Design We conducted a secondary analysis of a randomised, triple-blind, placebo-controlled trial of maternal vitamin D supplementation from June 2015 to October 2019.

Setting Antenatal care clinics in Dar es Salaam, Tanzania.

Participants Pregnant WLHIV and their offspring.

Interventions Daily 3000 IU …

Creating A Classroom Environment For Prekindergarten Students To Develop Social-Emotional Competencies And Transition Out Of The Step Program., Ayeshah N. Major

Theses and Dissertations

This mixed-methods study examined how the integration of Conscious Discipline and SEL-focused children’s literature can support the development of social-emotional competency in prekindergarten students. The problem of practice is that some children enter school without the foundational social-emotional skills necessary for successful learning and positive peer interactions. The purpose of this study is to identify strategies that support social-emotional growth and create an environment that aids STEP students in transitioning to a traditional prekindergarten classroom. Data was collected using parent questionnaires, student assessments, classroom observations, student interviews, and student drawings. The findings revealed that children’s literature provided accessible and meaningful …

The Daily Gamecock: September 2025, University Of South Carolina, Office Of Student Media

2025

No abstract provided.

Wave Intensity Analysis With Exercise Identifies Impairments In Pulmonary Hypertension, Christopher G. Lechuga, Farhan Raza, Mitchel J. Colebank, Claudia E. Korcarz, Jens C. Eickhoff, Naomi C. Chesler

Faculty Publications

Wave intensity analysis provides a novel approach to understanding the dynamic interactions between the right ventricle and pulmonary vasculature, particularly in pulmonary hypertension, a condition characterized by elevated pulmonary arterial pressures and vascular remodeling. This prospective study used wave intensity analysis to evaluate right ventricular and pulmonary vascular mechanics in 22 participants with pulmonary hypertension (including precapillary, isolated postcapillary, and combined pre/postcapillary pulmonary hypertension), and three without pulmonary hypertension. Forward and backward compression and decompression waves were quantified at rest and during incremental exercise (25, 50, and 75 W). Relationships between metrics of wave intensity analysis, hemodynamics, right ventricular function, …

Out Of The Vacuum: The Effect Of Tax Liability Changes On Compliance In The Presence Of Withholding Position And Group Affiliation, Chelsea Rae Austin, Donna Bobek Schmitt, Spenser G. Seifert

Faculty Publications

Prior research has established that tax liability increases lead to decreased compliance. However, tax liability changes do not happen in a vacuum. Notably, prior research has also identified a withholding phenomenon: individuals in a tax due position are less compliant than those in a refund position. Additionally, tax law changes are often enacted in politically polarized environments. We examine how three factors—tax liability changes, withholding position, and group affiliation—combine to influence individuals' tax compliance decisions. Our experimental results show that a tax increase is universally experienced as a loss, even when coupled with a tax refund and enacted by an …

Physical Function And Pain As Predictors Of Movement Behaviors In Adults With Arthritis, Scott Jamieson, Sarah Wilcox Phd, Chih-Hsiang Yang Ph.D., Ye Sil Kim Phd, Christine Pellegrini Ph.D.

Faculty Publications

Purpose

Design

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Measures

Analysis …

September 3, 2025 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.