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Meeting Abstracts From The 5th National Big Data Health Science Conference, Bankole Olatosi, Miranda Nixon, Xiaoming Li

Publications

No abstract provided.

I1: Introduction: Proceedings Of The 5Th National Big Data Health Science Conference, Bankole Olatosi, Miranda Nixon, Xiaoming Li

Publications

No abstract provided.

Novel Tetrazolium-Based Colorimetric Assay For Helicase Nsp13 In Sars-Cov-2, Triet M. Pham, Morgan G. Howard, Shane M. Carey, Lindsey R. Baker, Edward L. D'Antonio

Natural Sciences Faculty Publications

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a human pathogenic virus that encodes for a helicase (SC2Hel) that is essential for viral replication. SC2Hel has the ability to unravel dsRNA or dsDNA in an NTP-dependent manner from the 5′ to 3′ directionality. The standard helicase assay from studies involving SARS-CoV and SARS-CoV-2 have relied on the concept of fluorescence resonance energy transfer. Adding to the collection of helicase assays, herein, we have developed a novel tetrazolium-based colorimetric assay system for the detection of ADP that is produced via SC2Hel activity. This SC2Hel assay combines three enzyme-coupled steps involving the …

Reducing Non-Communicable Diseases Among Palestinian Populations In Gaza: A Participatory Comparative And Cost-Effectiveness Modeling Assessment, Sanjay Basu, John S. Yudkin, Mohammed Jawad, Hala Ghattas Ph.D., Bassam Abu Hamad, Zeina Jamaluddine, Gloria Safadi, Marie Elizabeth Ragi, Raeda El Sayed Ahmad, Eszter P. Vamos, Christopher Millett

Faculty Publications

We sought to assess the effectiveness and cost-effectiveness of potential new public health and healthcare NCD risk reduction efforts among Palestinians in Gaza. We created a microsimulation model using: (i) a cross-sectional household survey of NCD risk factors among 4,576 Palestinian adults aged ≥40 years old in Gaza; (ii) a modified Delphi process among local public health experts to identify potentially feasible new interventions; and (iii) reviews of intervention cost and effectiveness, modified to the Gazan and refugee contexts. The survey revealed 28.6% tobacco smoking, a 40.4% prevalence of hypertension diagnosis (with a 95.6% medication treatment rate), a 25.6% prevalence …

How Livelihood Change Affects Food Choice Behaviors In Low- And Middle-Income Countries: A Scoping Review, Emma Kenney Mph-Pa, Krystal K. Rampalli, Sharraf Samin, Edward A. Frongillo Ph.D., Ligia I. Reyes, Shiva Bhandari, Morgan Boncyk, Stella Nordhagen, Helen Walls, Sigrid Wertheim-Heck, Amy Ickowitz, Solveig A. Cunningham, Ramya Ambikapathi, Beatrice Ekesa, Mirriam Matita, Christine E. Blake Ph.D., Rd

Faculty Publications

Livelihoods have changed dramatically over the past decade in low- and middle-income countries (LMIC). These shifts are happening in tandem with shifts in individual and household food choice behaviors. This scoping review aimed to identify and characterize mechanisms through which livelihood changes could affect food choice behaviors in LMIC, including behaviors relating to food production, acquisition, preparation, distribution, and consumption. A literature search was conducted using 4 databases: PubMed, PsycInfo, AGRICOLA, and Embase. The search was further enhanced by expert solicitations. Studies were included if they measured or focused on a livelihood change, described or assessed a change in ≥1 …

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.

Technology Development And Materials Research To Enable A Sustainable D-T Fusion Energy Fuel Cycle, Brenda L. Garcia-Diaz, David Babineau, James Klein, Robert Allgood, George Larsen, Holly B. Flynn, Dale Hitchcock, Tim Krentz, Chris Dandeneau, Lucas Angelette, Robert Sindelar

Journal of the South Carolina Academy of Science

No abstract provided.

A 5-Year Longitudinal Structural Equation Model Of Social Isolation And Probable Major Depression Among Participants With Spinal Cord Injury, Chao Li, Susan Newman Phd, Rn, Crrn, Faan, Jillian M. Clark, James S. Krause

Publications

OBJECTIVE: To develop longitudinal structural models of social isolation and probable major depression (PMD) over a 5-year interval among participants with spinal cord injury (SCI). DESIGN: Longitudinal structural equation modeling of self-report assessments collected during two follow-ups (2013 as Time 1, 2018 as Time 2) of a 45-year multicohort longitudinal study. Participants (n = 557) were identified from a specialty hospital in the Southeastern United States and two Midwestern hospitals and were initially enrolled in 1973-1974, 1984-1985, 1993-1994, or 2003-2004. PMD symptomology was measured by the Patient Health Questionnaire-9 (PHQ-9) and was defined by PHQ-9 scores ≥ 10. Social isolation …

Adaptive Apparel For People With Disabilities: A Systematic Literature Review And Future Research Agenda, Md. Rafiqul Islam Rana M.S.,Ph.D, Kerri Mcbee-Black, Ishtehar Sharif Swazan

Faculty Publications

This systematic literature review examines research on adaptive apparel for people with disabilities (PWDs), an underrepresented consumer group. Using the scientific procedures and rationales for systematic literature reviews (SPAR-4-SLR) protocol and the theories, contexts, characteristics, and methods (TCCM) framework, 51 articles from three academic databases were analyzed based on specific keywords and inclusion/exclusion criteria. The review highlighted advancements addressing the needs of PWD consumers, such as innovative designs, user-centered methodologies, and inclusive marketing. However, there remain gaps in areas like disability types, methodologies, cultural factors, and societal barriers. The implications of this research underscore the urgent need for the apparel …

Employing Digital Pcr For Enhanced Detection Of Perinatal Toxoplasma Gondii Infection: A Cross-Sectional Surveillance And Maternalinfant Outcomes Study In El Salvador, Mary K. Lynn, Marvin Stanley Rodriguez Aquino, Pamela Michelle Cornejo Rivas, Xiomara Miranda, David F. Torres-Romero, Hanson Cowan, Madeleine M. Meyer, Willber D. Castro-Godoy, Mufaro Kanyangarara Ph.D., Stella C.W. Self Ph.D., Ms, Berry A. Campbell, Melissa S. Nolan Ph.D., Mph

Faculty Publications

Toxoplasma gondii is a parasitic infection that can be transmitted in utero, resulting in fetal chorioretinitis and other long-term neurological outcomes. If diagnosed early, pregnancysafe chemotherapeutics can prevent vertical transmission. Unfortunately, diagnosis of acute, primary infection among pregnant women remains neglected, particularly in low-andmiddle-income countries. Clinically actionable diagnosis is complex due to the commonality of infection during childhood and early adulthood which spawn long-last antibody titers and historically unreliable direct molecular diagnostics. The current study employed a cross-sectional T. gondii perinatal surveillance study using digital PCR, a next generation molecular diagnostic platform, and a maternal-fetal outcomes survey to ascertain the …

Maternal Care Utilization And Provision During The Covid-19 Pandemic: Voices From Minoritized Pregnant And Postpartum Women And Maternal Care Providers In Deep South, Ran Zhang, Tiffany Byrd, Shan Qiao Ph.D., Myriam E. Torres Phd, Msph, Xiaoming Li Ph.D., Jihong Liu Sc.D.

Faculty Publications

Background

The COVID-19 pandemic has significantly affected maternal care services especially for minoritized individuals, creating challenges for both service users (i.e., African American and Hispanic pregnant/postpartum women) and maternal care providers (MCPs). Guided by a socioecological framework, this study aims to investigate the experiences of African American and Hispanic pregnant and postpartum women, as well as MCPs, in accessing and providing maternal care services during the COVID-19 pandemic in the Deep South.

Methods

We conducted semi-structured interviews with 19 African American women, 20 Hispanic women, and 9 MCPs between January and August 2022. Participants were recruited from Obstetrics and Gynecology …

April 24, 2024 General Faculty Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Systematic Review On The Impacts Of Agricultural Interventions On Food Security And Nutrition In Complex Humanitarian Emergency Settings, Melodie Al Daccache, Berthe Abi Zeid, Leila Hojeij, Ghassan Baliki, Tilman Brück, Hala Ghattas Ph.D.

Faculty Publications

Complex humanitarian emergencies are a main driver of food and nutritional insecurity. Agricultural interventions are key to improving nutrition and food security, and their positive impacts are well-documented in stable developing countries. However, it is unclear if their positive effects on food security hold in complex emergency settings, too. In this paper, we systematically review empirical articles that apply rigorous designs to assess the causal impacts of agricultural interventions on food security, nutrition, or health outcomes in complex humanitarian emergencies. We only find six articles matching these criteria, which have mixed results on dietary diversity and food security, and little …

Messaging About Very Low Nicotine Cigarettes (Vlncs) To Influence Policy Attitudes, Harm Perceptions And Smoking Motivations: A Discrete Choice Experiment, Reed M. Reynolds, Lucy Popova, David L. Ashley, Katherine C. Henderson, Charity A. Ntansah, Bo Yang, Emily E. Hackworth, James Hardin, Jim F. Thrasher Ph.D., Ma, Ms

Faculty Publications

Background To reduce smoking and the harms it causes, countries, including the USA, are considering policies to reduce nicotine in combustible tobacco to minimally addictive levels. Effective messages about very low nicotine cigarettes (VLNCs) and this policy are crucial in combating misperceptions threatening the policy’s effectiveness.

Data and methods A discrete choice experiment assessed messages about VLNCs. Participants were 590 adults who smoked exclusively, 379 adults who both smoked and used e-cigarettes, 443 adults who formerly smoked and 351 young adults who never smoked (total n=1763). Seven message attributes were varied systematically (source, harm, chemicals, nicotine, satisfaction, addictiveness and quitting …

Identifying Multilevel Predictors Of Behavioral Outcomes Like Park Use: A Comparison Of Conditional And Marginal Modeling Approaches, Marilyn E. Wende, S. Morgan Hughey, Alexander C. Mclain, Shirelle Hallum, J. Aaron Hipp, Jasper Schipperijn, Ellen W. Stowe, Andrew T. Kaczynski Ph.D.

Faculty Publications

This study compared marginal and conditional modeling approaches for identifying individual, park and neighborhood park use predictors. Data were derived from the ParkIndex study, which occurred in 128 block groups in Brooklyn (New York), Seattle (Washington), Raleigh (North Carolina), and Greenville (South Carolina). Survey respondents (n = 320) indicated parks within one half-mile of their block group used within the past month. Parks (n = 263) were audited using the Community Park Audit Tool. Measures were collected at the individual (park visitation, physical activity, sociodemographic characteristics), park (distance, quality, size), and block group (park count, population density, age structure, racial …

The Daily Gamecock: April 2024, University Of South Carolina, Office Of Student Media

April

No abstract provided.

“A Perfect Storm”: Autistic Experiences Of Menopause And Midlife, Miranda J. Brady, Christine A. Jenkins, Rachel L. Moseley, Margaret Janse Van Rensburg

Faculty and Staff Publications

Previous research indicates that menopause can be an extremely difficult transition for some autistic people. This study asks how autistic people experience menopause and how they can better access services, support and information; autistic Community Research Associates played an important role in each stage of the research. Online focus groups and interviews were conducted with 24 autistic participants who lived in Canada (n = 13) or the United Kingdom (n = 11) and had experience with the menopausal transition. Transcripts were coded and analysed by four team members using reflexive thematic analysis. Four themes and eight subthemes were …

Improving Dementia Symptoms Through Personalized Music, Lindsay Grainger

SC Upstate Research Symposium

Alzheimer's disease and related dementia (ADRD) is a prevalent, costly, and complicated disease. With over 6 million Americans affected and the cost of treatment soaring to over $320 billion dollars annually, there is a growing need for low-cost interventions to treat symptoms. Routinely listening to personalized music selections has been shown to reduce agitation—the most common symptom of Alzheimer’s disease and related dementia. The purpose of this study was to provide a personalized music listening (PML) intervention of thirty minutes to 10 nursing home residents with dementia. Thirty-minute PML sessions occurred multiple times a week over six weeks. The inclusion …

The Evolution Of The Nonprofit Sector In Nepal, Charles Harrington, Davis Jones

SC Upstate Research Symposium

The nonprofit sector in Nepal has grown exponentially over the last decade. Significant growth in the areas of education, economic development, health and human services, tourism, and environmental conservation has created a demonstrable need for nonprofit organizational support and development to address these emerging needs. This paper and accompanying oral presentation will address the underlying factors that have driven the growth of the nonprofit sector in Nepal, including, but not limited to the history of national philanthropy and community service, early formulation of the nonprofit sector, development of civil society, non-government organizational proliferation, earthquake response and resilience, the emergence of …

Proposed Charlotte To Atlanta High-Speed Passenger Rail Line: An Economic, Infrastructural, And Developmental Analysis In The Upstate Of South Carolina, Ian C. Macurda, Kimberly Whitehead

SC Upstate Research Symposium

This research paper is an in-depth analysis of the high-speed passenger rail line proposed between Charlotte, NC and Atlanta, GA and its impact on the economy, infrastructure, and future development of the Upstate of South Carolina. Currently, passenger rail service between Charlotte and Atlanta is offered on Amtrak at late hours throughout the night on its long-distance passenger rail line The Crescent from New York City, NY to New Orleans, LA. The train is often delayed and is operating at a deficit for Amtrak, like most of their long-distance routes. Traffic on Interstate 85 through the Upstate is another issue …

Hse-8 The Revitalization Of The Hazel Green Academy, Josephine Traver, Jennifer M. Nguyen

SC Upstate Research Symposium

The Hazel Green Academy Revitalization Project is a community service-based project focused on restoring and repurposing the Hazel Green Academy (HGA). Established in 1880, HGA was a residential college-preparatory school located in Eastern Wolfe County, KY. At its height, HGA served not only as a school but also as a source of education and community events. Throughout the years, the academy expanded its facilities and resources to benefit both the students and the community. However, as free public schools emerged in the surrounding area during the 1930s, HGA faced a decline in enrollment. Consequently, HGA struggled for the next few …

Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk

SC Upstate Research Symposium

Purpose Statement: Several studies have shown that aerobic exercise can have a positive impact on alleviating symptoms experienced by individuals with Parkinson's disease (PD). Despite this evidence, the potential benefits of exercise for both PD patients and their care partners (PD dyad) remain unexplored. This research project investigates the effectiveness, therapeutic collaborations, and physical outcomes of a virtual reality (VR) tandem cycling program specifically designed for PD dyads.

Methods: Following approval from the Prisma Health Institutional Review Board, individuals with PD were identified and screened by clinical neurologists. The pre-testing measures for PD dyads (N=9) included emotional and cognitive status …

Hhp-3 Comparing Fitness Data Of Cadets In South Carolina To The General Population: A Pilot Study, Justen Chatman, Ming-Chi Sung, Matthew Brisebois

SC Upstate Research Symposium

BACKGROUND: To prepare for physically challenging environments, it is expected that military personnel achieve higher levels of physical fitness than the general population. The recent COVID-19 pandemic impacted physical activity levels among many of America’s youth, and thus, new recruits may be entering military service with lower fitness levels. It is also unknown how fitness levels of army cadets in upstate South Carolina compare to the general population. Therefore, the purpose of this pilot study was to compare anthropometric and fitness variables of army cadets from upstate South Carolina to data from the general population. METHODS: A sample of 22 …

Hhp-8 Barriers And Facilitators To Regular Physical Activity And Healthy Eating Behaviors In Schools: Perspectives Of South Carolina School Personnel, Logan J. Camp-Spivey, Susan D. Newman, Robert N. Stevens, Michelle Nichols

SC Upstate Research Symposium

Background: In South Carolina (SC), 42% of youth are overweight or obese. Two sets of modifiable behaviors contributing to obesity are physical activity (PA) and dietary habits. School-based interventions have successfully improved these behaviors. The purpose of this study was to identify SC public school personnel perspectives on the most common barriers and facilitators to regular PA and healthy eating behaviors in schools.
Methods: A needs assessment survey was conducted with school personnel statewide. There were 17 questions on the survey that addressed: (1) demographic information about participants’ educational backgrounds, (2) barriers to regular PA and healthy eating behaviors in …

Identifying A Group Of Factors Predicting Cognitive Impairment Among Older Adults, Longgang Zhao, Yuan Wang, Eric Mishio Bawa, Zichun Meng, Jingkai Wei, Sarah Newman-Norlund, Tushar Trivedi, Hatice Hasturk, Roger Newman-Norlund, Julius Fridriksson Ph.D., Anwar T. Nerchant

Faculty Publications

Background

Cognitive impairment has multiple risk factors spanning several domains, but few studies have evaluated risk factor clusters. We aimed to identify naturally occurring clusters of risk factors of poor cognition among middle-aged and older adults and evaluate associations between measures of cognition and these risk factor clusters.

Methods

We used data from the National Health and Nutrition Examination Survey (NHANES) III (training dataset, n = 4074) and the NHANES 2011–2014 (validation dataset, n = 2510). Risk factors were selected based on the literature. We used both traditional logistic models and support vector machine methods to construct a composite score …

Do “In The Family” Coaching Hires Outperform External Hires In Ncaa Division I Men’S Basketball, Maxfield Lane, Nels Popp, Jonathan A. Jensen

Journal of Issues in Intercollegiate Athletics

When conducting searches to fill head coaching positions, many college athletics directors frequently look to candidates who have a connection to the university; former players, assistant coaches, or students. Hiring someone from a university’s “family” is often a popular decision among stakeholders, but utilizing such parameters in a search severely restricts candidate pools. More importantly, little empirical evidence suggesting such hires perform better. The purpose of the current study was to examine whether NCAA Division I men’s basketball coaches who are “In the Family” hires perform better than “External” hires in measures of (a) team success and (b) recruiting. The …

April 3, 2024 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Associations Between Sleep Duration, Sleep Disturbance And Cardiovascular Disease Biomarkers Among Adults In The United States, Prince Nii Ossah Addo, Paddington T. Mundagowa, Longgang Zhao, Mufaro Kanyangarara, Monique J. Brown Ph.D., Mph, Jihong Liu Sc.D.

Faculty Publications

Background

Sleep problems are associated with abnormal cardiovascular biomarkers and an increased risk of cardiovascular diseases (CVDs). However, studies investigating associations between sleep problems and CVD biomarkers have reported conflicting findings. This study examined the associations between sleep problems and CVD biomarkers in the United States.

Methods

Data were from the National Health and Nutrition Examination Survey (NHANES) (2007–2018) and analyses were restricted to adults ≥ 20 years (n = 23,749). CVD biomarkers [C-reactive Protein (CRP), low-density lipoproteins, high-density lipoproteins (HDL), triglycerides, insulin, glycosylated hemoglobin (HbA1c), and fasting blood glucose] were categorized as abnormal or normal using standardized cut-off …

The Contribution Of The South Carolina Technical College System To Human Capital, Labor Force Participation, And Employment, Justin Land

Senior Theses

This thesis assesses the economic impact of the South Carolina Technical College System by applying a counterfactual analysis method to the study of human capital development and labor force growth from 2010-2019. Data from the U.S. Census Bureau and the Integrated Postsecondary Education Data System (IPEDS) are used to estimate the average years of schooling attained by a South Carolinian during the period and the counterfactual average were the Technical College System to not exist. This result is then combined with probit regression models of labor force participation and employment to estimate the Technical College System’s contribution to the labor …

The Effect Of Dental Insurance Coverage And Economic Fluctuations On Oral Health Outcomes In The United States, Laura Singletary

Senior Theses

Proper oral health is imperative to overall health, but obstacles often persist in

receiving proper oral health care. Lack of dental insurance coverage and economic recessions are two main factors contributing to oral health outcomes. Extended time without cleanings or addressing current oral health concerns exacerbates oral health problems into more costly procedures for the patient that are conveniently not covered by many insurance plans. This thesis investigates the oral health outcomes associated with periods following economic downturns, specifically citing the time of the Great Recession from 2007-2009.