Digital Commons Network^™

An Exploratory Study To Understand Factors Associated With Health-Related Quality Of Life Among Uninsured/Underinsured Patients As Identified By Clinic Providers And Staff, Guillermo M. Wippold, Nwakaego Nmezi, Jaime L. Williams, Jacqueline Butler, Tanya M. Hodge

Faculty Publications

Since the release of Healthy People 2020, there has been extensive research understanding factors associated with health-related quality of life (HRQoL) among specific populations. Despite this growing body of research, little has been conducted to understand the factors associated with HRQoL among uninsured/underinsured Americans. The purposes of the present study were to assess clinic staff to determine: (1) whether there is a need to examine HRQoL among uninsured/underinsured individuals, (2) whether there is a need for tailored HRQoL-promoting interventions among uninsured/underinsured individuals, and (3) the factors associated with HRQoL among uninsured/underinsured individuals. A survey was sent to an association of …

Student Spotlights - 2020, Upstate Account

University of South Carolina Upstate Student Research Journal

Each volume of USC Upstate’s Student Research Journal reserves a section to celebrate the efforts, activities, and successes of our students. The spotlights are typically divided into two major categories: Alumni Spotlights and Nontraditional Student Spotlights. Students featured in the Alumni Spotlight section are nominated by faculty members excited about the transition of USC Upstate students into jobs and professional programs following graduation. Students featured in the Nontraditional Student Spotlight section are nominated by faculty members impressed by the advanced time management skills and multitasking abilities of students facing extra challenges during their tenure at USC Upstate (e.g., return to …

Extensive Morphological Variability In Asexually Produced Planktic Foraminifera, Catherine V. Davis, Caitlin M. Livsey, Hannah M. Palmer, Pincelli M. Hull, Ellen Thomas, Tessa M. Hill, Claudia R. Benitez-Nelson

Faculty Publications

Marine protists are integral to the structure and function of pelagic ecosystems and marine carbon cycling, with rhizarian biomass alone accounting for more than half of all mesozooplankton in the oligotrophic oceans. Yet, understanding how their environment shapes diversity within species and across taxa is limited by a paucity of observations of heritability and life history. Here, we present observations of asexual reproduction, morphologic plasticity, and ontogeny in the planktic foraminifer in laboratory culture. Our results demonstrate that planktic foraminifera reproduce both sexually and asexually and demonstrate extensive phenotypic plasticity in response to nonheritable factors. These two processes fundamentally explain …

Recent Decisions

The Journal of Law and Education

No abstract provided.

Paradise Lost?: A New Legal Theory To Combat Climate Change In South Carolina, Anna C. Parham

South Carolina Law Review

No abstract provided.

Can Children Catch Up From The Consequences Of Undernourishment? Evidence From Child Linear Growth, Developmental Epigenetics, And Brain And Neurocognitive Development, Jef L. Leroy, Edward A. Frongillo Jr., Pragya Dewan, Maureen M. Black, Robert A. Waterland

Faculty Publications

Recovery from nutritionally induced height deficits continues to garner attention. The current literature on catch-up growth, however, has 2 important limitations: wide-ranging definitions of catch-up growth are used, and it remains unclear whether children can recover from the broader consequences of undernutrition. We addressed these shortcomings by reviewing the literature on the criteria for catch-up in linear growth and on the potential to recover from undernutrition early in life in 3 domains: linear growth, developmental epigenetics, and child brain and neurocognitive development. Four criteria must be met to demonstrate catch-up growth in height: after a period in which a growth-inhibiting …

Does Marriage, Employment And Having Children Matter? A Secondary Analysis On Physical Activity Levels, Leisure Time Physical Activity, And Social Roles Among Women In The United States, Tramaine Paul Mcmullen

Theses and Dissertations

Background: Social roles, such as being married, employed, or having children, have been shown to have independent negative relationships with moderate to vigorous physical activity (MVPA) levels among women. Increasing the number of women with children that meets physical activity guidelines is critical to reduce chronic disease and early mortality in this population. However, few studies have examined the relationship between holding multiple social roles, MVPA, and leisure-time physical activity (LTPA) among women with children. The study had two aims: 1) to determine the relationship between objectively measured MVPA by social roles and 2) to examine the frequency of specific …

Research Provides Evidence For Health Policy In Lao Pdr, Ian Bromage, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Sengchanh Kounnavong, Vanphanom Sychareun, Léonie Venroij

Publications

No abstract provided.

Determinants Of Nutrition Agenda Setting In The Context Of The Double Burden Of Malnutrition In Tamil Nadu, India, Shilpa Vimalananda Constantinides

Theses and Dissertations

The double burden of malnutrition is increasing in low- and middleincome countries, with economic, social, and health consequences. Policies and programs to address malnutrition at the national and subnational levels reflect the priorities and framing of the problem by the stakeholder community. Previous studies have examined if and how nutrition-related NCDs have been included into national nutrition policy agendas that have historically focused on reduction of undernutrition, but little is known about if or how this process occurs at the subnational level where policies are translated and implemented according to local contexts, priorities, and frames of nutrition-related NCDs.

We aimed …

Mechanistic Insight On Vibrio Gazogenes Mediated Intervention Of Aflatoxin Biosynthesis In Aspergillus Flavus, Rubaiya Jesmin

Theses and Dissertations

Aflatoxin is a liver carcinogen, mycotoxin, and a secondary metabolite that is produced by some plant pathogens within the genus Aspergillus when they infect crops such as corn, peanuts, and cotton. Given the significant adverse health and economic impacts of aflatoxin and a predicted rise of crop contamination with mycotoxins caused by a changing climate, there is a pressing need for exploring new aflatoxin mitigation methods. Previous studies in our laboratory have shown that metabolites from Vibrio gazogenes, an estuarine non-pathogenic bacterium, can inhibit aflatoxin synthesis. However, a direct interaction study between V. gazogenes and aflatoxin producing strains has …

17 Β-Estradiol And Phytoestrogens Attenuate Apoptotic Cell Death In Hiv-1 Tat Exposed Primary Cortical Cultures, Sheila Marie Adams

Theses and Dissertations

Despite the advent of highly active antiretroviral therapy (HAART), neurological disorders develop in most people infected with human immunodeficiency virus type 1 (HIV-1). The poor CNS delivery of anti-retrovirals allows continued virus production and renders neurons susceptible to the toxic effects of released viral proteins. The neurotoxic potential of HIV-1 viral protein Tat has been shown to include excitotoxicity, oxidative stress, and mitochondrial dysfunction leading to subsequent cell death. Thus, Tat is thought to have a key role in the pathogenesis of HIV-associated neurodegeneration. Estrogens are universally considered to be neuroprotective, as such; estrogens have positive implications in the treatment …

Correlates Of Maternal Health Service Use And Women’S Experiences Using Antenatal Care In Ghana: A Mixed-Methods Study, Anna Cofie

Theses and Dissertations

The pace of improvements in maternal mortality has been slow in Ghana. While Ghana’s maternal mortality ratio (MMR) decreased from 635 per 100,000 live births to 319 per 100,000 live births between 1990 and 2015, the country failed to meet the 75% reduction target set by Millennium Development Goal (MDG) goal 5A, to reduce maternal mortality ratio by 75% between 1990 and 2015. Antenatal care (ANC) is critical to improving maternal morbidity and mortality and child deaths. In 2003, Ghana introduced the National Health Insurance Scheme to ensure that all pregnant women have access to free maternal care, and in …

Association Between Urinary Enterolignans As A Marker For Gut Microbiome Diversity And Depression In Nhanes, Marie Knoll

Theses and Dissertations

Depression is a chronic disease which inflicts functional and emotional impairment that has been a growing issue in the United States (US). Depression is the most prevalent mental disorder in the US and is the leading cause of disability in the world. By 2030, It is projected that major depressive disorder will be the second largest contributor to global burden of disease. Causes of depression are still largely unknown and treatments are often expensive, time consuming, and only available to certain populations. Treatment often requires a combination of medicines and therapy to be effective. In recent years, the gut microbiome …

Intracranial Atherosclerotic Stenosis And Its Association With Inflammation And Meditarrenean Diet, Tushar Trivedi

Theses and Dissertations

Intracranial Atherosclerotic Stenosis (ICAS) is associated with 8 to 10% of all strokes in the U.S. Although there is some evidence that in the Asian population inflammation plays a role in asymptomatic ICAS, it has not been shown in the U.S. population. Prior studies have shown associations between diet and regulation of inflammation. Mediterranean dietary pattern has been associated with lower levels of inflammation and cardiovascular disease (CVD). In light of the important role of inflammation in intermediate stroke risk factors including atherosclerotic disease, and potential role of diet in modulating inflammation, understanding individuals’ diets according to their inflammatory properties …

Bayesian Zero-Inflated Model For Ordinal Data, Huizhong Yang

Theses and Dissertations

Datasets with a relatively large number of zeros is commonly seen in medical applications. Although models like Zero-inflated Poisson (ZIP) model are proposed for counts data, there is still some issues with ordinal data which have excess zeros. In this paper, we developed a Bayesian approach to accommodate the excess zero in ordinal data. Intellectual disability (ID), also known as mental retardation (MR), is a disability characterized by below-average intelligence or mental ability and a lack of the learning necessary skills for daily life. A person with intellectual disability has intellectual functioning and adaptive behaviors limitations. Intellectual disability is a …

The Effects Of Organic Products On Conventional Products And Retailer Assortment Planning, Zhihao Zhang

Theses and Dissertations

The rapid growth in organic products has posed a major challenge to conventional retailer assortment planning. On the one hand, conventional retailers, driven by the relatively high margins of organic products, have increased organic product offerings. On the other hand, the shelf space for conventional retailers has remained the same, with newly opened stores much smaller in sizes. Therefore, retailers need to carefully manage their conventional product assortments to harvest the benefit of offering and increasing organic product assortments. In order to manage the assortment efficiently, conventional retailers need to understand how organic products would affect their existing products, consumers, …

Spatiotemporal Dynamics Of Benthic Microalgae In South Carolina Shelf Sediments, Sarah N. Zaunbrecher

Theses and Dissertations

Benthic microalgae (BMA) play essential roles in food webs and regulating nutrient exchange at the sediment-water interface in continental shelf ecosystems. However, shelf BMA are not widely studied due to the difficulties sampling the upper few millimeters of shelf sediments. A few published studies have highlighted the high spatiotemporal distribution of BMA, but detailed explanations for this known variability are limited. The objectives of this study were to quantify BMA biomass variability on scales of cm to km and relate these measurements to in situ nutrient concentrations, sediment grain size, in situ irradiance, depth, and other environmental factors. Water and …

The Singing Voice Specialist: An Essential Bridge Between Two Worlds, Rebecca Holbrook Loar

Theses and Dissertations

For more than 35 years, voice teachers have been seeking an educational platform to adequately prepare a Singing Voice Specialist. Several degree ideas have been proposed, none of which have been fully implemented, leaving the field of Singing Voice Specialty without a certifying body or way to achieve licensure or certification. This document seeks to uncover the current progress in the field of Singing Voice Specialty, the progression of educational programs geared toward Singing Voice Specialization, possible accrediting associations, and future education needed to propel this profession forward.

In seeking these answers, experts within various aspects of voice care are …

Examining The Organizational Capacity Of Public Libraries That Offer Obesity Prevention Programs, Olivia Whitt

Theses and Dissertations

Supplemental Nutrition Assistance Program Education (SNAP-Ed) is a federally funded grant program that helps SNAP-eligible populations make healthy choices, like those outlined by the Dietary Guidelines for Americans and the Physical Activity Guidelines for Americans. Together with implementation agencies (IAs) and local sites, SNAP-Ed provides direct nutrition education and facilitates policy, systems, and environmental strategies (PSEs) such as farmers markets and community gardens. This qualitative research investigated two specific aims: 1.) Understand the elements of organization capacity that influence a public library’s ability to implement obesity prevention programs and 2.) Evaluate the need for library staff public health knowledge …

Understanding The Influence Of Changing Climate On Mycotoxin Contamination Of Food And Indoor Fungi-Mediated Respiratory Illness, Mayomi Helen Omebeyinje

Theses and Dissertations

Over the years, climate change has been a major core issue in public and environmental health. The World Health Organization (WHO) estimated that about 250,000 additional death per year would be attributed to climate change between 2030 and 2050 if this situation persists. Since our population depends on (but not limited to) the availability of clean water, good air quality, and exposure to environmental hazards/pathogens, the overall health impact caused by climate change is likely to be overwhelming in the nearest future. This dissertation explored the influence of climate change on fungi diseases and pathogenesis after severe weather conditions (hurricanes …

Understanding The Role Of Political Commitment And Coherence Across Sectors And Across National And Sub-National Levels In Enabling Improvements In Nutrition In Rwanda, Elyse Iruhiriye

Theses and Dissertations

Reducing undernutrition is on the political agendas of many low- and middle-income countries. There is general consensus that to improve nutritional outcomes involves actions across the different sectors that influence both the immediate and underlying determinants of optimal nutrition and an enabling environment to support the political and policy processes. Despite renewed attention over the last 15 years, addressing nutrition in a multisectoral way was previously promoted in the 1970’s but failed to have sustained political commitment due to its organizational complexities to plan and implement strategies across sectors.

We conducted an in-depth retrospective case study to understand how Rwanda, …

Nutrient Timing: A Garage Door Of Opportunity?, Shawn M. Arent, Harry P. Cintineo, Bridget A. Mcfadden, Alexa Jenny Chandler, Michelle Angelique Arent

Faculty Publications

Nutrient timing involves manipulation of nutrient consumption at specific times in and around exercise bouts in an effort to improve performance, recovery, and adaptation. Its historical perspective centered on ingestion during exercise and grew to include pre- and post-training periods. As research continued, translational focus remained primarily on the impact and outcomes related to nutrient consumption during one specific time period to the exclusion of all others. Additionally, there seemed to be increasing emphasis on outcomes related to hypertrophy and strength at the expense of other potentially more impactful performance measures. As consumption of nutrients does not occur at only …

Genome-Wide Identification And Characterization Of Snrk Family Genes In Brassica Napus, Weizhuo Zhu, Dezhi Wu, Lixi Jiang, Lingzhen Ye

Publications

BACKGROUND: Sucrose non-fermenting 1 related protein kinases (SnRK) play crucial roles in responding to biotic and abiotic stresses through activating protein phosphorylation pathways. However, little information of SnRK genes was available in Brassica napus, one of important oil crops. Recently, the released sequences of the reference genome of B.napus provide a good chance to perform genome-wide identification and characterization of BnSnRK gene family in the rapeseed. RESULTS: Totally 114 SnRK genes distributed on 19 chromosomes were identified in the genome of B.napus and classified into three subfamilies on the basis of phylogenetic analysis and the domain types. According to gene …

American Heart Association Epi|Lifestyle Scientific Sessions: 2020 Meeting Highlights, Alexander C. Razavi, Véronique Gingras, Erin D. Michos, Ann Marie Navar, Sherry Ann Brown, Erin Delker, Kathryn Foti, Stéphanie Harrison, Yifei Lu, Jovia L. Nierenberg, Jewel Scott Phd, Rn, Fnp-C, Olive Tang, Alvin G. Thomas, Ruth Alma Turkson-Ocran, Amelia Wallace, Mingyu Zhang, Kristie J. Lancaster, Pamela L. Lutsey, Elizabeth Selvin

Faculty Publications

No abstract provided.

American Heart Association Epi|Lifestyle Scientific Sessions: 2020 Meeting Highlights, Alexander C. Razavi, Véronique Gingras, Erin D. Michos, Ann Marie Navar, Sherry Ann Brown, Erin Delker, Kathryn Foti, Stéphanie Harrison, Yifei Lu, Jovia L. Nierenberg, Jewel Scott Phd, Rn, Fnp-C, Olive Tang, Alvin G. Thomas, Ruth Alma Turkson-Ocran, Amelia Wallace, Mingyu Zhang, Kristie J. Lancaster, Pamela L. Lutsey, Elizabeth Selvin

Faculty Publications

No abstract provided.

Linking Activity, Nutrition, And Child Health (Launch): Protocol For A Longitudinal Cohort Study Of Children As They Develop From Infancy To Preschool Age, Russell R. Pate, Edward A. Frongillo Jr., Kerry Cordan, Marsha Dowda, Alexander C. Mclain, Myriam E. Torres, William H. Brown, Agnes Bucko, Emily R. Shull

Faculty Publications

Background

Physical activity is known to provide important health benefits in children ages 3 years and above, but little is known about the effects of physical activity on health in very young children under age 3. LAUNCH (Linking Activity, Nutrition, and Child Health) is a study designed to expand the body of knowledge on development of physical activity behavior and associations between physical activity and other health characteristics as children transition from infancy to preschool age.

Methods

Physical activity and sedentary behavior will be measured objectively in young children over a period of 30 months. Each child will complete a …

Covid19, The Pandemic Which May Exemplify A Need For Harm-Reduction Approaches To Eating Disorders: A Reflection From A Person Living With An Eating Disorder, Margaret Janse Van Rensburg

Faculty and Staff Publications

This reflective piece, written by a woman with an eating disorder aims to identify the impact of COVID-19 on persons living with eating disorders and provide a social justice approach as a resolution. The author identifies that eating disorder behaviors may be the only coping tool available for many persons with eating disorders during this time of uncertainty. While she acknowledges the risks associated with eating disorder behaviors, she identifies that this time of uncertainty may be a time to embrace harm-reduction in approaching the health and wellness of persons with eating disorders.

Responding To Health Needs Of Women, Children And Adolescents Within Syria During Conflict: Intervention Coverage, Challenges And Adaptations, Chaza Akik, Aline Semaan, Linda Shaker-Berbari, Zeina Jamaluddine, Ghada E. Saad, Katherine Lopes, Joanne Constantin, Abdulkarim Ekzayez, Neha S. Singh, Karl Blanchet, Jocelyn Dejong, Hala Ghattas Ph.D.

Faculty Publications

Background:

Women and children suffer disproportionately in armed-conflicts. Since 2011, the protracted Syrian crisis has fragmented the pre-existing healthcare system. Despite the massive health needs of women and children, the delivery of key reproductive, maternal, newborn, child and adolescent health and nutrition (RMNCAH&N) interventions, and its underlying factors are not well-understood in Syria. Our objective was to document intervention coverage indicators and their implementation challenges inside Syria during conflict.

Methods:

We conducted 1) a desk review to extract RMNCAH&N intervention coverage indicators inside Syria during the conflict; and 2) qualitative interviews with decision makers and health program implementers to …

Effect Of Differences In Month And Location Of Measurement In Estimating Prevalence And Trend Of Wasting And Stunting In India In 2005-2006 And 2015-2016, Emily M. Madan, Edward A. Frongillo Jr., Sayeed Unisa, Laxmikant Dwivedi, Robert Johnston, Abner Daniel, Praween K. Agrawal, Sila Deb, Ajay Khera, Purnima Menon, Phuong H. Nguyen

Faculty Publications

Background: Child undernutrition in India remains widespread. Data from the National Family Health Survey 3 and 4 (NFHS-3 and NFHS-4) suggest that wasting prevalence has increased while stunting prevalence has declined. Objective: The objectives of this study were to do the following: ) describe wasting and stunting by month of measurement in India in children surveys, and ) test whether differences in the timing of anthropometric data collection and in states between survey years introduced bias in the comparison of estimates of wasting and stunting between NFHS-3 and NFHS-4. Methods: Data on wasting and stunting for 42,608 and 232,744 children …

Objective Church Environment Audits And Attendee Perceptions Of Healthy Eating And Physical Activity Supports Within The Church Setting, Marilyn E. Wende, Andrew T. Kaczynski, John A. Bernhart, Caroline G. Dunn, Sarah Wilcox

Faculty Publications

Interventions in faith-based settings are increasingly popular, due to their effectiveness for improving attendee health outcomes and behaviors. Little past research has examined the important role of the church environment in individual-level outcomes using objective environmental audits. This study examined associations between the objectively measured physical church environment and attendees’ perceptions of physical activity (PA) and healthy eating (HE) supports within the church environment, self-efficacy for PA and HE, and self-reported PA and HE behaviors. Data were collected via church audits and church attendee surveys in 54 churches in a rural, medically underserved county in South Carolina. Multi-level regression was …