Digital Commons Network^™

Meat Alternatives: The State Of The Industry, Barriers To Adoption, And Overcoming Barriers, Steven Maler

Senior Theses

The world faces many environmental problems that can be linked to human activity, including links to the production of food. The meat industry is often seen as a major contributor to such problems. Meat alternatives are often proposed as a way to address these environmental problems. However, these products face barriers when it comes to their adoption by consumers, and firms that produce meat alternatives must overcome these barriers to be successful. I used data from a variety of academic works, newspaper articles, research reports, and company websites to find that these barriers are related to taste, nutrition, convenience, expense, …

Ironing Out Anemia: Assessing The Role Of Marketplace Factors And Government Investment Incentives In Shaping East African Pharmaceutical Markets, Madison M. Bradley

Senior Theses

Africa suffers from the highest disease burden in the world, with over half of the population lacking regular access to essential medicines (Owoeye, 2014, p.214; Chaudhuri & West, 2015, p.23). Following two decades of reform, the continent has now emerged one of the fastest-growing economic regions, shifting public health focus toward non-communicable diseases (NCDs) (Holt et al., 2015, p.2). Among these NCDs is anemia, which has direct and indirect economic effects as large as 4.05% of GDP (Horton & Ross, 2003, p.51). Encouraged by the rapid growth of liberalized markets, African governments and health officials are now considering local pharmaceutical …

The Failed Quest For Equal Educational Opportunity: Regulating Education The Way We Regulate Business, Stephen Sugarman

The Journal of Law and Education

No abstract provided.

Genes Related To Redox And Cell Curvature Facilitate Interactions Between Caulobacter Strains And Arabidopsis, Louis Berrios, Bert Ely

Faculty Publications

Bacteria play an integral role in shaping plant growth and development. However, the genetic factors that facilitate plant-bacteria interactions remain largely unknown. Here, we demonstrated the importance of two bacterial genetic factors that facilitate the interactions between plant-growth-promoting (PGP) bacteria in the genus Caulobacter and the host plant Arabidopsis. Using homologous recombination, we disrupted the cytochrome ubiquinol oxidase (cyo) operon in both C. vibrioides CB13 and C. segnis TK0059 by knocking out the expression of cyoB (critical subunit of the cyo operon) and showed that the mutant strains were unable to enhance the growth of Arabidopsis. In addition, disruption of …

The Effect Of A Folate Free Diet On Tumor Burden And Chemotherapy Effectiveness, Kendall E. Stalls

Senior Theses

Our research is to understand the effect of the microbiota on colorectal cancer. Evidence has been shown that the microbiota is linked to the development and progression of colorectal cancer. The research focuses on how the gut microbiome influences the effectiveness of colorectal cancer treatments. Specifically, how the composition of the microbiota and the metabolites that it secretes changes the response to chemotherapy. We also research how tumor burden can be altered through changing the composition of the gut bacteria. Our experiments are performed on APC/Min+ mice, that have been genetically altered to have colon cancer. We conducted an experiment …

Female Athlete Triad: Evaluation Of The Cumulative Risk Assessment Tool For Female Collegiate Athletes, Jessica Pia

Senior Theses

Content: As the pressure on collegiate and elite female athletes to perform at their highest possible capabilities has grown, so to have the consequences associated with their high energy expending lifestyles. The Female Athlete Triad (Triad) is a syndrome defined as having one or more of the following conditions: LEA with or without disordered eating, menstrual dysfunction, and/or low BMD. Due to potential long-term, irreversible health consequences of the Triad, the Female Athlete Triad Coalition developed a risk assessment tool known as the Triad CRA to identify at-risk athletes and subsequent return-to-play status. Objective: To determine the risk …

Purification And Functional Characterization Of The Iron-Responsive Transcription Factor Aft1 From C. Glabrata, Jade Ikahihifo-Bender

Senior Theses

Due to its unique ability to serve as both an electron donor and acceptor, iron is utilized as a co-factor for many biological processes, including electron transfer, oxygen binding, and vitamin synthesis. Iron is also a key factor during fungal infections as the human host and invading pathogens battle over limited iron pools. The primary iron-responsive transcription factor Aft1 in the opportunistic pathogenic yeast Candida glabrata responds to iron deficiency by activating expression of iron acquisition genes. However, the mechanisms for sensing intracellular iron levels and regulating Aft1 activity in response to iron are unknown. The C. glabrata iron regulation …

Defining Septicemia Incidence And Mortality In South Carolina Through Access To Health Care, Behavioral Health, And Low Socio-Economic Status, Raeann Vossberg

Senior Theses

This study aims to provide an in-depth view of septicemia mortality and incidence in the state of South Carolina through the lenses of socio-economic factors, access to healthcare, and behavioral health factors. This study was conducted using data from the South Carolina Revenue and Fiscal Affairs Office, utilizing their Hospitalization, Inpatient, Emergency Department, and Outpatient data both separately and combined depending on the data point, along with additional data sources for support (see works cited). We hypothesize that the higher rates of septicemia mortality and incidence in the southeastern United States, as well as in South Carolina in particular, could …

Barriers To Healthy Births At Nigerian Hospitals, Caroline Johnston

Senior Theses

Maternal mortality is a problem everywhere, but it is especially dangerous in Nigeria where the average woman experiences pregnancy six times during her lifetime (Population Reference Bureau, 2001). Many researchers focus on the medical complications associated with labor, such as hemorrhage, eclampsia, or infection. Although these birth complications are the direct sources of maternal death, it is also important to recognize how maternal mortality is a multifaceted issue influenced by local cultural groups, religions, politics, poverty level and the absence of basic infrastructures. Although maternal mortality is interconnected with social and geographical elements, my paper concentrates on Nigerian hospitals and …

Are Adverse Childhood Experiences Associated With Health Behaviors Among College Students: Emotion Regulation As A Potential Moderator, Margaret Winters

Senior Theses

In this study, we sought to examine the relations among adverse childhood experiences (ACEs), physical activity (PA), sleep quality, and emotion regulation in college students. ACEs have been proven to have a dose-response relation with adverse health outcomes in adulthood, including heart disease, cancer, lung disease, liver disease, poor mental health, and risky health behaviors (Felitti et al., 1998; Merrick et al., 2016; Zhang et al., 2020). ACEs have also been previously associated with poor sleep quality and emotion dysregulation (Kajeepeta, Gelaye, Jackson, & Williams, 2015[WL1] ; Kim & Cicchetti, 2010). Given these findings, we sought to examine how …

Limitations And Consequences Of Migrant And Refugee Healthcare- An Analysis Of The Current State Of Migrant Health, Meghan Herilla

Senior Theses

Migrants and refugees are an often-neglected specialized population in the field of healthcare, although making up over 14% of the world’s population.

The following paper examines the current state of migrant healthcare, including but not limited to ease of access, quality of care, and the accompanying stigmatization of immigrants in general. It then analyzes current policies, both national and global, influencing the healthcare of immigrants in both the United States and abroad. Finally, a comparison of migrant healthcare in the United States versus Thailand shows how the current U.S. healthcare system can be improved to better accommodate migrants and refugees. …

The Benefits Of A More Physically Active Workforce In The Corporate World, Dillon M. Billingham-Hemminger, Jacob D. Locke

Senior Theses

With the ever-expanding knowledge of the benefits of physical activity and good general health for all aspects of our lives, it should be quite surprising that activity levels are declining at accelerating rates. After taking a deeper look into the probable cause for this phenomenon, it becomes clearer that the increasing pressures of workplace culture are leading to more sedentary lifestyles.

This paper looks at the benefits of physical activity on people and on corporations, specifically workplace disease prevention and wellness programs, to see if there exists a mutualistic relationship between the two. For people, physical activity was consistently found …

The Inflammatory Potential Of Diet And Its Relationship With Metabolic, Mental, And Cardiovascular Health Among Childhood Cancer Survivors: The St. Jude Lifetime Cohort Study (Sjlife), Christian Ricardo Alvarado

Theses and Dissertations

Background: Diet is now known to play an important role in the process of inflammation and subsequent chronic health events, such as cancer, metabolic syndrome (MetS), anxiety, depression, and cardiovascular disease (CVD). The Dietary Inflammatory Index (DII®) and energy-adjusted DII (E-DIITM) are tools that can estimate the inflammatory potential of diet of individuals. Previous research has focused predominantly on diet-associated inflammation and adverse health effects in populations that were not composed of cancer survivors. As of the time of this dissertation, none have focused on childhood cancer survivors. Childhood cancer survivors are at an elevated risk of suffering from an …

The Dietary Inflammatory Index Is Associated With Low Muscle Mass And Low Muscle Function In Older Australians, Marlene Gojanovic, Kara L. Holloway-Kew, Natalie K. Hyde, Mohammadreza Mohebbi, Nitin Shivappa Mbbs, Mph, Ph.D., James R. Hébert Scd., Adrienne O'Neil, Julie A. Pasco

Faculty Publications

Age-associated chronic, low grade systemic inflammation has been recognised as an important contributing factor in the development of sarcopenia; importantly, diet may regulate this process. This cross-sectional study examined the association of diet-related inflammation with components of sarcopenia. Participants (n = 809) aged 60–95 years from the Geelong Osteoporosis Study were studied. Body composition was measured by dual energy X-ray absorptiometry. In this study, low appendicular lean mass (ALM/height2, kg/m2) was defined as T-score < −1 and low muscle function as Timed-Up-and-Go >10 s over 3 m (TUG > 10). Dietary inflammatory index (DII®) scores, based on specific foods and nutrients, were computed using dietary data collected from a …

From Stigma To Dignity? Transforming Workfare With Universal Basic Income And A Federal Job Guarantee, Lynn D. Lu

South Carolina Law Review

No abstract provided.

The Role Of Sexting In The Development Of Romantic Relationships, Max Bretscher

Theses and Dissertations

Using Knapp's stage theory of relationship communication, this pilot study examines "sexting" in the broader framework of relationship development, from initiation to termination. Likert-scale questions (1 = highly unlikely; 2 = highly likely) and open-ended questions were administered through Qualtrics to a small population (N = 45) of undergraduate mass communication students to determine on what communication technology, and in which stage(s) of relationships, is sexting most likely to occur. Quantitative results showed that Snapchat was considered the most appropriate medium for sexts (M = 4.60), followed by texting (4.27). Research that these mediums are used when relationships reach a …

Thinking Like An Historian: Improving Engagement Through Project-Based Learning In A United States History Classroom, George Gray

Theses and Dissertations

The purpose of this action research study is to determine the efficacy of project-based learning activities for improving students’ critical thinking skills and engagement in the classroom. South Carolina’s creation of the United States History end-of-course assessment has led many social studies teachers to design ‘teach to the test’ lesson plans, which this researcher’s students seem to find mundane and uninspiring. Although these teaching methods have helped some students perform well on the end-of-course test, these tactics have sapped their interest in social studies and have not prepared them to be responsible citizens in an active democracy. The social studies …

Genes Related To Redox And Cell Curvature Facilitate Interactions Between Caulobacter Strains And Arabidopsis, Louis Berrios, Bert Ely

Faculty Publications

Bacteria play an integral role in shaping plant growth and development. However, the genetic factors that facilitate plant-bacteria interactions remain largely unknown. Here, we demonstrated the importance of two bacterial genetic factors that facilitate the interactions between plant-growth-promoting (PGP) bacteria in the genus Caulobacter and the host plant Arabidopsis. Using homologous recombination, we disrupted the cytochrome ubiquinol oxidase (cyo) operon in both C. vibrioides CB13 and C. segnis TK0059 by knocking out the expression of cyoB (critical subunit of the cyo operon) and showed that the mutant strains were unable to enhance the growth of …

Examination Of Energy Needs And Female Athlete Triad Components In Competitive Cheerleaders, Allison Smith

Theses and Dissertations

The sport of cheerleading has grown immensely over the recent decades. The current sport requires full body athletic abilities like gymnastics, ballet, and swimming and diving. These sports have previously reported high rates of eating disorder (ED) risk, body image dissatisfaction, and Female Athlete Triad (Triad) components (low energy availability with or without and eating disorder, menstrual cycle dysfunction, and low bone mineral density). Scientific research examining these factors within cheerleaders has been limited. The purpose of this study was to examine overall ED risk across cheerleading team type (All-Star, college), squad type (all-girl, coed), and by position (flyer, base, …

Applications And Mechanisms Of Near Infrared Spectroscopy For Age Estimation In Otoliths Of Red Snapper Lutjanus Campechanus, Michelle S. Passerotti

Theses and Dissertations

Near infrared spectroscopy (NIRS) is a light spectroscopy method useful for non-invasively discriminating and quantifying chemical composition of a wide variety of substances. Recently-developed applications of NIRS to fish age estimation across a range of taxa have sparked intense interest in exploring the feasibility of its use for rapid age estimation in fisheries population management. In this pursuit, development of species-specific calibration models relating traditionally-derived age estimates (i.e., those estimated from growth band counts) to NIR spectral signatures from ageing structures is required to derive predictive models that can then estimate age from rapid scans of whole ageing structures alone. …

The Interactive Effects Of Nontoxic Levels Of Microplastics - Textile Microfibers And Tire Wear Particles, On The Acute Toxicity Of Bifenthrin In The Estuarine Grass Shrimp, Palaemonetes Pugio, Xiaoxuan Fan

Theses and Dissertations

Contemporary pollution issues are primarily focused on Contaminants of Emerging Concern (CECs) which may include Brominated and Fluorinated flame retardants, Pharmaceuticals and Personal Care Products (PPCPs), Contemporary Use Pesticides (CUPs), nanomaterials and microplastics (Muraya et al., 2014). Tire wear particles and textile microfibers are examples of CECs which may gradually increase in the environment and may cause adverse effect on the health of some aquatic species (Marwood et al., 2011; Taylor et al., 2016). Microplastic particles are so small that they can be ingested by many marine species such as filter feeders and small particle feeders including mollusk and crustaceans, …

Panaxynol’S Pharmacokinetic Properties And Its Mechanism Of Action In Treating Ulcerative Colitis, Hossam Sami Tashkandi

Theses and Dissertations

Panaxynol (PA) is a polyacetylene that was found to be an abundant active ingredient in American ginseng (AG). Pharmacokinetics (PK) studies of PA were conducted to determine how the body reacts to it by using liquid chromatography-tandem mass spectrometry (LC-MS/MS) to measure PA’s concentration. In vitro, PA’s clearance by microsome metabolism is a moderate 48.1 minutes. In vivo, CD-1® mice were treated with PA by intravenous (IV) injection or orally (PO). Concentrations of PA were measured in plasma and tissue using LC-MS/MS. Also, PA has a high bioavailability of 50.4% and a moderate half-life of 5.9 hours. In addition, mice …

A Study Of The Social, Cultural, And Environmental Influences On Appalachian Agriculture, Morganne May

Senior Theses

Appalachia, despite its rich history and abundant biological and cultural diversity, is commonly associated with a generalized notion of ignorance, resistance to progress, and "backwardness." This study aims to shed light on the socioeconomic, cultural, and environmental influences which have shaped the present food systems of Appalachia through a review of relevant literature. This history provides the necessary context to strategize a region-specific, socioeconomically and environmentally sustainable food system moving forward.

Examining The Relationship Of Blood Transfusions And Acute Morbidity In Preterm Infants, Kayla Chavis Everhart

Theses and Dissertations

Preterm infants, those that are born less than 37 weeks gestational age, often suffer major morbidity and mortality during hospitalization in the neonatal intensive care unit due to their prematurity; one of the major morbidities is Necrotizing Enterocolitis, a devastating gastrointestinal disease. The exact aspects that cause preterm infants to develop Necrotizing Enterocolitis are unknown; however, our hypothesis is preterm infant thermal stability and/or preterm infant stress around packed red blood cell transfusions are etiological factors in the relationship between these necessary transfusions and morbid outcomes such as Necrotizing Enterocolitis.This dissertation includes an in-depth background and introduction of various morbid …

Previvor And High-Risk Breast Cancer Patients’ Opinions On A Specialized Management Clinic, Madeleine Nicole Tjoelker

Theses and Dissertations

Approximately 5-10% of cancers are thought to be hereditary, caused by pathogenic variants in genes associated with inherited cancer syndromes. Previvors, individuals who have a higher predisposition to cancer due to genetic or other risk factors, have specific healthcare and psychological needs that may be better served by a specialized management clinic. This study compared the experiences of previvors who had access to a specialized management clinic with those who did not, in order to better understand the unique needs of previvors. This study utilized a mixed methods design including an online survey (N=26) and semi-structured phone interview …

Exploring Effects Of Sample Storage, Preparation, And Tissue Type On Fourier Transform-Near Infrared Spectroscopy (Ft-Nirs) Ageing Across Fish Taxa, Keith Fuller

Theses and Dissertations

The accurate determination of age for fish is a vital part of both populationmanagement and ichthyological research. However, the methods which are primarily employed to age fish can be difficult, time consuming, inaccurate, or some combination thereof. Most ageing is currently done via hard parts (such as otoliths, vertebrae, or scales) which are read in a manner similar to tree rings with markings corresponding to known or presumed periods of time. Recently, Fourier transform-near infrared spectroscopy (FT-NIRS) has been investigated as a novel tool to age fish more quickly and objectively. This method works by recording the vibrational frequencies of …

Ready Or Not For K5: A Study On Early Childhood Interventions Within Special Education And General Education Setting, Paulette Mizzell

Theses and Dissertations

This action research study describes how using the Enhanced Alphabet Knowledge model affects preschool students' readiness for Kindergarten. The theoretical framework that supported this study was based on Cindy Jones', Sarah Clark's, and D. Ray Reutzel's Enhanced Alphabet Knowledge Method (2013). This study used quantitative data to further indicate the impact and importance of early intervention classrooms. The participants of this study included eight students from one preschool intervention class. Data collection instruments included pre-and post- phonological awareness literacy screening scores and a teacher questionnaire. Results of this study indicated that the majority of student participants experienced an increase in …

Effect Of Oxidative Stress On Lifespan And Cellular Survival, Benedicth Onyeka Ukhueduan

Theses and Dissertations

When cells experience oxidative stress, the integrated stress response (ISR) signaling pathway is activated. One of the first outcomes of such ISR-activated response is to temporarily halt protein synthesis, which aids in cellular recovery. However, if cells cannot recover from the stress, they activate the cell death pathways which kills the affected cells, usually by apoptosis, which can then lead to either acquisition or prevention of diseases depending on the situation. In physiological aging, a compromised stress response is observed as an organism ages, which leads to disrupted homeostasis and elevated risk of disease. Thus, longevity of an organism is …

A Multilevel And Spatial Analysis Of Oral And Pharyngeal Cancer In South Carolina, Deborah M. Hurley

Theses and Dissertations

Objective: Disparities in the distribution of oral and pharyngeal cancer exist worldwide. This is also true in the United States and in South Carolina. Differences exist in oral and pharyngeal cancer stage and survival by race and sex, with higher incidence rates for Whites but higher proportions of late-stage cancer and lower survival for Blacks. This study was conducted to evaluate whether any differences exist in the spatial distribution of oral and pharyngeal cancer stage at diagnosis and survival, and to evaluate the association of income inequality, material deprivation and other measures of social determinants of health (contextual risk factors) …

Feasibility Of Integrating Survivors Of Stroke Into Cardiac Rehabilitation: A Mixed Methods Pilot Study, Elizabeth W. Regan, Reed Handlery, Jill C. Stewart, Joseph Lee Pearson Ms,Drph, Sara Wilcox Ph.D., Stacy Fritz

Faculty Publications

Background Survivors of stroke are often deconditioned and have limited opportunities for exercise post-rehabilitation. Cardiac Rehabilitation (CR), a structured exercise program offered post-cardiac event in the United States (U.S.), may provide an opportunity for continued exercise.

The purpose of this study was to examine the feasibility of integrating survivors of stroke into an existing, hospital-based CR program through an assessment of (1) recruitment, uptake and retention, (2) adherence and fidelity, (3) acceptability and (4) safety.

Methods A mixed methods design combined a single group, pre-post design, pilot feasibility study with an imbedded qualitative inquiry. Survivors of stroke were recruited into …