Digital Commons Network^™

The Role Of Exercise Dose On Ghrelin Concentration In Postmenopausal Women, Kimberly Bowyer

Theses and Dissertations

Introduction: As obesity continues to be a major public health concern, exercise is continually at the forefront of combating this epidemic. This thesis aims to examine how two different doses of exercise may affect the “hunger hormone”, ghrelin; in postmenopausal, non-obese women. Methods: 54 non-obese postmenopausal women were randomly assigned to either a higher dose (energy expenditure = 14 kilocalories/per kilogram of body weight/per week) or lower dose (energy expenditure = 8 kcal/kg/week) aerobic exercise training group for 16 weeks. Fasting blood samples were taken at baseline and at post intervention for analysis of ghrelin via multiplex immunoassay. Results: Only …

Association Of Freestanding Dialysis Facility Size, Quality Incentive Program Scores And Patient Survival, Fozia Ajmal

Theses and Dissertations

Background

In 2011, The Centers for Medicare and Medicaid Services (CMS) has introduced a bundled payment reform along with a Quality Incentive Program (QIP) to bring efficiency in End stage renal disease (ESRD) care. The QIP rates facilities using clinical and reporting criteria, but misses out on patient outcomes. It penalizes facilities not achieving a target score by 0-2% of payments. The small facilities are expected to be impacted more by a reduction in payments. We determined the association between ESRD facility size and QIP scores and the association between QIP scores and patient survival.

Methods

We used the Medicare …

Best Practice For Screening Adult Patients With Psoriasis For Polyautoimmunity: Celiac Disease, Rheumatoid Arthritis And Crohn’S Disease, Susan Danielle Ashbaugh

Theses and Dissertations

The purpose of this quality improvement project was to determine if screening primary care patients with psoriasis will improve early detection of celiac disease (CD), rheumatoid arthritis, and Crohn’s disease (CrD). The aim of this project is to assess the utility of early screening in patients with psoriasis in order to facilitate earlier diagnosis of CD, RA and CrD, which would consequently initiate earlier treatment and improve long-term patient outcomes. Genetic and population-based studies suggest that individuals with psoriasis have a greater risk of also having CrD, CD or RA, than do individuals without psoriasis. The literature also suggests that …

The Regulation Of Glycoprotein130 Dependent Inflammatory Cytokines One Basal And Mechanical Stimuli Induced Protein Synthesis In Myotubes And Skeletal Muscles, Song Gao

Theses and Dissertations

Maintaining skeletal muscle mass has a well-documented role in health and quality of life. Two members of IL-6 family of cytokines, IL-6 and LIF, and have a paradoxical role in skeletal muscle mass regulation: short term elevation of IL-6 and LIF plays a key role in mechanical stimuli induced muscle growth and muscle hypertrophy, while the long term elevated IL-6 and LIF regulate muscle wasting during cancer cachexia by disrupting muscle protein turnover regulation. The regulation of muscle protein synthesis is an important determinant of mechanical stimuli induced muscle hypertrophy and muscle wasting during cancer cachexia. IL-6 family of cytokines …

Embodied Madness: Contextualizing Biological Stress Among 19th And 20th-Century Institutionalized Euro-American Women, Madeline M. Atwell

Theses and Dissertations

The late 19th and early 20th-centuries in the United States were periods in which white women of middle and low socio-economic status were admitted into insane asylums at a higher rate than men for the first time in recorded history. An existent body of literature helps us to comprehend the social and cultural climate in which the institutionalization of women was both acceptable and commonplace; yet few studies have paired this research with the information that can be revealed on the bones of those institutionalized. A sample of 53 institutionalized women from the Robert J. Terry Anatomical Collection were analyzed …

Losing Weight With Five A’S (5 A’S): Assess, Advise, Agree, Assist, Arrange Framework And Motivational Interviewing (Mi) For Health Behavior Change Counseling, Jacqueline Baer

Theses and Dissertations

According to the Centers for Disease Control and Prevention (CDC), obesity has reached epidemic levels and has associated with increased risk of morbidity and mortality rates. The increasing prevalence of obesity is a major public health concern. Researchers calculate that health care costs are 44% higher among moderately and severely obese older persons than for persons at normal weights. Seventy-five percent of African American (AA) women are overweight and obese according to data from the CDC and The State of Obesity: Better Policies for a Healthier America. Compared to any other racial ethnic group, AA women are more likely to …

Prenatal Methylmercury Exposure Through Rice Consumption In Rural China, Chuan Hong

Theses and Dissertations

Background: Methylmercury is one of the most toxic forms of mercury, which severely afflicts the developing fetus. Methylmercury exposure occurs not only through fish consumption but also through rice consumption. However, rice does not contain the same beneficial micronutrients that fish/shellfish has. Therefore, prenatal methylmercury exposure through maternal rice consumption may potentially increase adverse health effects on the developing fetus.

Objectives: The purpose of this dissertation was to investigate the magnitude of prenatal methylmercury exposure through rice consumption and the relationship between maternal mercury biomarkers and birth outcomes.

Methods: A total of 398 pregnant women were recruited at parturition in …

Depressive Symptoms Association With Health Outcomes And Treatment In Older Americans With Diabetes, Lashonda Jovon Williams

Theses and Dissertations

Introduction: Diabetes remains the 7th leading cause of death in the United States. Diabetes is a major public health concern of its own, but when you add the comorbidity of depression, diabetes outcomes are amplified. This dissertation examines how depressive symptomatology and treatment for depression are associated with selfreported health (SRH) and diabetes control.

Methods: Chi-square and logistic regression were used to analyze data from the Health and Retirement Study (2012). We assessed the associations between SRH and diabetes control with depressive symptomatology data.

Results: In our sample (n=4374), 19% of respondents reported high depressive symptomatology and …

Early Life Factors And Health Outcomes In Children And Mothers, Olubunmi Olufunke Orekoya

Theses and Dissertations

This dissertation focused on early life exposures and their impact on children and mothers’ health. It consists of three distinct studies with an overarching goal of understanding how early life factors influence health outcomes among children and mothers. The broad aims are: 1) to examine the association between maternal gestational weight gain and offspring weight at 1 year, while assessing the mediating role of birth weight; 2) to determine the association between breastfeeding practices and development of allergic conditions (eczema/skin allergy, hay fever/respiratory allergy, and asthma); and 3) to examine the association between breastfeeding and postpartum weight retention at 12 …

Picturing Rest: A Photovoice Study Of African American Women’S Perceptions And Practices Of Rest, Eboni T. Herbert Harris

Theses and Dissertations

African American women are consistently identified as being less likely to participate in sustained leisure time physical activity (Tussing-Humphreys, Fitzgibbon, Kong, & Odoms-young, 2013), yet more likely to be overweight or obese (Levi, Segal, Laurent, & Rayburn, 2014). There has been a wide range of initiatives directed towards preventing and/or reducing obesity among African Americans, such as targeted physical activity and nutrition interventions involving goal setting, group and individualized counseling, and social support. Previous research focused on African American women’s perceptions toward physical activity, nutrition, and weight; emphasize the consideration of cultural attitudes like placing a high value on rest …

Exploring Spatial Patterning And The Impact Of Obesogenic Built Environments For Youth Obesity, S. Morgan Hughey

Theses and Dissertations

Youth obesity is a major public health concern due to an array of physical, social, and psychological health consequences. Residential location, often referred to as ‘place’, has continued to emerge as a key health determinant with studies showing that where a child lives impacts their health. Environments where it is easy for individuals to have low levels of physical activity – either by discouraging active behavior or promoting sedentary behavior – and easy for individuals to consume unhealthful foods – either by the limited availability of healthful foods or increased availability of unhealthy foods – have been coined ‘obesogenic’. Additional …

The Daily Gamecock, Thursday, January 26, 2017, University Of South Carolina, Office Of Student Media

January

No abstract provided.

The Daily Gamecock, Thursday, March 30, 2017, University Of South Carolina, Office Of Student Media

March

No abstract provided.

The Daily Gamecock, Wednesday, August 9, 2017, University Of South Carolina, Office Of Student Media

August

No abstract provided.

The Daily Gamecock, Wednesday, August 9, 2017, University Of South Carolina, Office Of Student Media

August

No abstract provided.

The Daily Gamecock, Friday, August 18, 2017, University Of South Carolina, Office Of Student Media

August

No abstract provided.

The Daily Gamecock, Monday, January 9, 2017, University Of South Carolina, Office Of Student Media

January

No abstract provided.

The Trade System And Climate Action: Ways Forward Under The Paris Agreement, Susanne Droege, Harro Van Asselt, Kasturi Das, Michael Mehling

South Carolina Journal of International Law and Business

No abstract provided.

Service-Learning: An Interpretive Case Study Of Teachers’ Perspectives And Planning Strategies, Cory Susanne Miller

Theses and Dissertations

This interpretive case study focused on elementary teachers who were implementing a service-learning project in their classroom. Research suggests that service-learning is beneficial for students and is becoming more prevalent in high schools and universities. Current literature, however, provides little evidence for the use of service-learning at the elementary level. The purpose of this study was to explore and gain insight in to how elementary school teachers use service learning and to examine underlying factors that shape and influence how teachers plan for and implement service learning projects. This study aims to provide a planning model to support elementary teachers …

Creating Equitable Access Pathways For All Students In South Carolina? A Study Of Sc International Baccalaureate Diploma Programs, Diane D. Padula

Theses and Dissertations

This case study adds insight to the idea of equitable access as it relates to advanced coursework available to students in public high schools in South Carolina. The International Baccalaureate Diploma Program (IBDP) has become a viable choice since secondary-level magnet programs in SC have taken root for over thirty years. The IBDP originally developed in SC to attract the global elite, however in the recent decade, the IBDP has morphed into a program meant for all students. The concept of IB for All is marketed as a college readiness program within South Carolina IBDP schools. Access is multidimensional; it …

The Decision-Making Process For Individuals At Risk For Hereditary Diffuse Gastric Cancer, Alexa Prose

Theses and Dissertations

Hereditary diffuse gastric cancer (HDGC) is caused by mutations in the CDH1 gene. Individuals who carry mutations in the CDH1 gene have as high as an 80% lifetime risk for gastric cancer. To reduce the high lifetime risk of gastric cancer, CDH1 mutation carriers are recommended to undergo a prophylactic total gastrectomy (TG). Individuals within this at-risk population face a difficult task of deciding whether to have genetic testing for the CDH1 mutation and to have a prophylactic TG. Currently, there is little research that examines the factors influencing decision-making for this population and their specific informational and support needs. …

Altered Gut Microbiome In A Mouse Model Of Gulf War Illness Causes Neuroinflammation And Intestinal Injury Via Leaky Gut And Tlr4 Activation, Firas Alhasson, Suvarthi Das, Ratanesh K. Seth, Diptadip Dattaroy, Varun Chandrashekaran, Caitlin N. Ryan, Luisa S. Chan, Traci Testerman, James Burch, Lorne J. Hofseth, Ronnie Horner, Mitzi Nagarkatti, Prakash Nagarkatti, Stephen M. Lasley, Saurabh Chatterjee

Faculty Publications

Many of the symptoms of Gulf War Illness (GWI) that include neurological abnormalities, neuroinflammation, chronic fatigue and gastrointestinal disturbances have been traced to Gulf War chemical exposure. Though the association and subsequent evidences are strong, the mechanisms that connect exposure to intestinal and neurological abnormalities remain unclear. Using an established rodent model of Gulf War Illness, we show that chemical exposure caused significant dysbiosis in the gut that included increased abundance of phylum Firmicutes and Tenericutes, and decreased abundance of Bacteroidetes. Several gram negative bacterial genera were enriched in the GWI-model that included Allobaculum sp. Altered microbiome caused significant decrease …

Socially Assigned Race, Reactions To Perceived Racial Discrimination And Type Ii Diabetes Mellitus, Jourdyn A. Lawrence

Theses and Dissertations

Background: Numerous studies have utilized race to document health inequities. As race is considered a social classification of persons based upon physical traits, studies have begun to consider socially assigned race defined as the race/ethnicity perceived by others. Socially assigned race may serve as the basis for differential or unfair treatment of persons ascribed to historically oppressed groups. Socially assigned race may also provide additional insight into racial health disparities, particularly among Latino populations who are commonly defined by their ethnicity. This study assesses the relationship between self-identified and socially assigned race/ethnicity and tests the moderating effects of emotional and …

Association Between Diabetes And Cancer In Indian And Us Populations Using Longitudinal Study Design, Shraddha S. Vyas

Theses and Dissertations

Background: There is growing evidence of association between diabetes and cancer. No studies have been conducted in India evaluating this association. With the current epidemiologic, nutritional and economic transition in India, it becomes extremely important to examine this association in an Indian population. Additionally, difference in association exists based on different cancer subtypes. Research has shown that diabetes is associated with an increased risk of colorectal cancer. However most of these studies suggest detection bias to be one of the probable reasons for this association. Additionally, the common risk factors shared by both these conditions are considered to one of …

Paleodemographic And Biochemical Analysis Of Urbanization, Famine, And Mortality, Brittany S. Walter

Theses and Dissertations

Urbanization is a transitional period often associated with deteriorating population health and increased mortality, as the rapid increase of population density in urban centers facilitates the transmission of infectious diseases, unsanitary living conditions, and precarious food supplies. Research on the transition to an urban environment in the past offers a temporal depth to our understanding of the consequences of urbanization that cannot be accomplished through examination of contemporary populations. This project integrates paleodemographic (hazard analysis) and biochemical (stable isotope analysis) approaches to examine the health and diet of inhabitants in late medieval England (c. 1120-1539 CE), specifically the relationship between …

Maternal Physical Activity And Cardiorespiratory Fitness During Pregnancy And Its Relation To Infant Size, Samantha M. Mcdonald

Theses and Dissertations

Recent evidence indicates that U.S.-born infants are larger today compared to 20 years ago. A strong determinant of neonatal size is maternal body mass, where larger mothers deliver larger infants. Consistent evidence indicates that higher levels of maternal physical activity (PA) during pregnancy reduce the risk of delivering a larger infant. However, this protective effect has only been demonstrated in normal weight pregnant women. Little is known about the relationship between maternal PA and neonatal size in overweight or obese pregnant women. Moreover, no studies have examined the association between maternal cardiorespiratory fitness (CRF), an indicator of habitual PA, on …

The Impact Of A Reflective Practice Series On The Awareness Level Of Six Teacher Candidates At A Public University In The Southeast, Lindsay M. Sturkie

Theses and Dissertations

This study examined the impact of a Reflective Practice Series (RPS) on the awareness level of preservice teachers enrolled in a field experience course in a teacher education program at a university in the southeast United States. This study took place during the Fall 2016 semester with six participants, two early childhood majors, two elementary majors, and two middle level majors. Data were collected through pre- and post-questionnaires, course assignments, and field observations. The results revealed that the teacher candidates were able to make connections between theory and reflective teaching, had varying viewpoints about the process of reflection, and most …

Children’S Obesogenic Behaviors During Summer Versus School, Keith Brazendale

Theses and Dissertations

Emerging evidence shows children gain 3-5 times the amount of weight and lose cardiorespiratory fitness (CRF) during summer compared to the 9-months of the school year. Notably, this trend is more pronounced in children who are already overweight or obese going into summer and/or from low-income ethnic minority households. There is little evidence to investigating the underlying mechanisms driving the pronounced occurrence of these negative health outcomes during summer.

The purpose of this dissertation as a whole was to investigate children’s obesogenic behaviors (physical activity, sedentary/ screen time, sleep, and diet) during summer versus school, and compare any differences in …

Identifying Associations Between Religious Commitment And Preventive Health Behaviors In A Southeastern Rural County, Nathan A. Peters

Theses and Dissertations

Health disparities within the United States (US) are continuing to impact ethnic minorities living in rural areas nationwide. In response, there is growing interest in using faith-based settings as vehicles to deliver much needed disease prevention interventions. However, few studies have identified the relationship between private and public religious commitment, individually, and the behaviors or risk factors associated with chronic disease. The purpose of this study was to observe the association between religious commitment, both private (i.e., time spent trying to grow in one’s religious understanding) and public (i.e., frequency of attendance, time spent in fellowship with others) individually, and …

Effects Of A Mindfulness Based Intervention On Diurnal Cortisol In Cancer Survivors, Susannah Small

Theses and Dissertations

Background. There are approximately 15.5 million individuals alive today in the U.S. with a personal history of cancer. For this large and growing population, ill effects associated with cancer diagnosis and treatment include both physical and psychosocial symptoms adversely affecting quality of life. One low-risk alternative to conventional pharmaceutical use in treating these symptoms is mindfulness practice. Research on self-reported measures provides strong evidence that this type of intervention improves quality of life for cancer survivors, but evidence of impact on objective measures is limited. Cortisol, the body’s primary stress hormone, is one relatively easy to measure indicator that …