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A Sensor-Based Simulation Method For Spatiotemporal Event Detection, Yuqin Jiang, Andrey A. Popov, Zhenlong Li, Michael E. Hodgson, Binghu Huang May 2024

A Sensor-Based Simulation Method For Spatiotemporal Event Detection, Yuqin Jiang, Andrey A. Popov, Zhenlong Li, Michael E. Hodgson, Binghu Huang

Faculty Publications

Human movements in urban areas are essential to understand human–environment interactions. However, activities and associated movements are full of uncertainties due to the complexity of a city. In this paper, we propose a novel sensor-based approach for spatiotemporal event detection based on the Discrete Empirical Interpolation Method. Specifically, we first identify the key locations, defined as “sensors”, which have the strongest correlation with the whole dataset. We then simulate a regular uneventful scenario with the observation data points from those key locations. By comparing the simulated and observation scenarios, events are extracted both spatially and temporally. We apply this method …


Structural Homology Of Mite Profilins To Plant Profilins Is Not Indicative Of Allergic Cross-Reactivity, Andrea O'Malley, Sahana Sankaran, Avery Carriuolo, Kriti Khatri, Krzysztof Kowal, Maksymilian Chruszcz Ph.D. Apr 2024

Structural Homology Of Mite Profilins To Plant Profilins Is Not Indicative Of Allergic Cross-Reactivity, Andrea O'Malley, Sahana Sankaran, Avery Carriuolo, Kriti Khatri, Krzysztof Kowal, Maksymilian Chruszcz Ph.D.

Faculty Publications

Structural and allergenic characterization of mite profilins has not been previously pursued to a similar extent as plant profilins. Here, we describe structures of profilins originating from Tyrophagus putrescentiae (registered allergen Tyr p 36.0101) and Dermatophagoides pteronyssinus (here termed Der p profilin), which are the first structures of profilins from Arachnida. Additionally, the thermal stabilities of mite and plant profilins are compared, suggesting that the high number of cysteine residues in mite profilins may play a role in their increased stability. We also examine the cross-reactivity of plant and mite profilins as well as investigate the relevance of these profilins …


Systematic Review On The Impacts Of Agricultural Interventions On Food Security And Nutrition In Complex Humanitarian Emergency Settings, Melodie Al Daccache, Berthe Abi Zeid, Leila Hojeij, Ghassan Baliki, Tilman Brück, Hala Ghattas Ph.D. Apr 2024

Systematic Review On The Impacts Of Agricultural Interventions On Food Security And Nutrition In Complex Humanitarian Emergency Settings, Melodie Al Daccache, Berthe Abi Zeid, Leila Hojeij, Ghassan Baliki, Tilman Brück, Hala Ghattas Ph.D.

Faculty Publications

Complex humanitarian emergencies are a main driver of food and nutritional insecurity. Agricultural interventions are key to improving nutrition and food security, and their positive impacts are well-documented in stable developing countries. However, it is unclear if their positive effects on food security hold in complex emergency settings, too. In this paper, we systematically review empirical articles that apply rigorous designs to assess the causal impacts of agricultural interventions on food security, nutrition, or health outcomes in complex humanitarian emergencies. We only find six articles matching these criteria, which have mixed results on dietary diversity and food security, and little …


Identifying Multilevel Predictors Of Behavioral Outcomes Like Park Use: A Comparison Of Conditional And Marginal Modeling Approaches, Marilyn E. Wende, S. Morgan Hughey, Alexander C. Mclain, Shirelle Hallum, J. Aaron Hipp, Jasper Schipperijn, Ellen W. Stowe, Andrew T. Kaczynski Ph.D. Apr 2024

Identifying Multilevel Predictors Of Behavioral Outcomes Like Park Use: A Comparison Of Conditional And Marginal Modeling Approaches, Marilyn E. Wende, S. Morgan Hughey, Alexander C. Mclain, Shirelle Hallum, J. Aaron Hipp, Jasper Schipperijn, Ellen W. Stowe, Andrew T. Kaczynski Ph.D.

Faculty Publications

This study compared marginal and conditional modeling approaches for identifying individual, park and neighborhood park use predictors. Data were derived from the ParkIndex study, which occurred in 128 block groups in Brooklyn (New York), Seattle (Washington), Raleigh (North Carolina), and Greenville (South Carolina). Survey respondents (n = 320) indicated parks within one half-mile of their block group used within the past month. Parks (n = 263) were audited using the Community Park Audit Tool. Measures were collected at the individual (park visitation, physical activity, sociodemographic characteristics), park (distance, quality, size), and block group (park count, population density, age structure, racial …


The Daily Gamecock: April 2024, University Of South Carolina, Office Of Student Media Apr 2024

The Daily Gamecock: April 2024, University Of South Carolina, Office Of Student Media

April

No abstract provided.


“A Perfect Storm”: Autistic Experiences Of Menopause And Midlife, Miranda J. Brady, Christine A. Jenkins, Rachel L. Moseley, Margaret Janse Van Rensburg Apr 2024

“A Perfect Storm”: Autistic Experiences Of Menopause And Midlife, Miranda J. Brady, Christine A. Jenkins, Rachel L. Moseley, Margaret Janse Van Rensburg

Faculty and Staff Publications

Previous research indicates that menopause can be an extremely difficult transition for some autistic people. This study asks how autistic people experience menopause and how they can better access services, support and information; autistic Community Research Associates played an important role in each stage of the research. Online focus groups and interviews were conducted with 24 autistic participants who lived in Canada (n = 13) or the United Kingdom (n = 11) and had experience with the menopausal transition. Transcripts were coded and analysed by four team members using reflexive thematic analysis. Four themes and eight subthemes were …


Discovery Of Strong 3-Nitro-2-Phenyl-2h-Chromene Analogues As Antitrypanosomal Agents And Inhibitors Of Trypanosoma Cruzi Glucokinase, Shane M. Carey, Destiny M. O’Neill, Garrett B. Conner, Julian Sherman, Ana Rodriguez, Edward L. D'Antonio Apr 2024

Discovery Of Strong 3-Nitro-2-Phenyl-2h-Chromene Analogues As Antitrypanosomal Agents And Inhibitors Of Trypanosoma Cruzi Glucokinase, Shane M. Carey, Destiny M. O’Neill, Garrett B. Conner, Julian Sherman, Ana Rodriguez, Edward L. D'Antonio

Natural Sciences Faculty Publications

Chagas disease is one of the world’s neglected tropical diseases, caused by the human pathogenic protozoan parasite Trypanosoma cruzi. There is currently a lack of effective and tolerable clinically available therapeutics to treat this life-threatening illness and the discovery of modern alternative options is an urgent matter. T. cruzi glucokinase (TcGlcK) is a potential drug target because its product, D-glucose-6-phosphate, serves as a key metabolite in the pentose phosphate pathway, glycolysis, and gluconeogenesis. In 2019, we identified a novel cluster of TcGlcK inhibitors that also exhibited anti-T. cruzi efficacy called the 3-nitro-2-phenyl-2H-chromene analogues. This was achieved by performing a target-based …


Hhp-8 Barriers And Facilitators To Regular Physical Activity And Healthy Eating Behaviors In Schools: Perspectives Of South Carolina School Personnel, Logan J. Camp-Spivey, Susan D. Newman, Robert N. Stevens, Michelle Nichols Apr 2024

Hhp-8 Barriers And Facilitators To Regular Physical Activity And Healthy Eating Behaviors In Schools: Perspectives Of South Carolina School Personnel, Logan J. Camp-Spivey, Susan D. Newman, Robert N. Stevens, Michelle Nichols

SC Upstate Research Symposium

Background: In South Carolina (SC), 42% of youth are overweight or obese. Two sets of modifiable behaviors contributing to obesity are physical activity (PA) and dietary habits. School-based interventions have successfully improved these behaviors. The purpose of this study was to identify SC public school personnel perspectives on the most common barriers and facilitators to regular PA and healthy eating behaviors in schools.
Methods: A needs assessment survey was conducted with school personnel statewide. There were 17 questions on the survey that addressed: (1) demographic information about participants’ educational backgrounds, (2) barriers to regular PA and healthy eating behaviors in …


Do “In The Family” Coaching Hires Outperform External Hires In Ncaa Division I Men’S Basketball, Maxfield Lane, Nels Popp, Jonathan A. Jensen Apr 2024

Do “In The Family” Coaching Hires Outperform External Hires In Ncaa Division I Men’S Basketball, Maxfield Lane, Nels Popp, Jonathan A. Jensen

Journal of Issues in Intercollegiate Athletics

When conducting searches to fill head coaching positions, many college athletics directors frequently look to candidates who have a connection to the university; former players, assistant coaches, or students. Hiring someone from a university’s “family” is often a popular decision among stakeholders, but utilizing such parameters in a search severely restricts candidate pools. More importantly, little empirical evidence suggesting such hires perform better. The purpose of the current study was to examine whether NCAA Division I men’s basketball coaches who are “In the Family” hires perform better than “External” hires in measures of (a) team success and (b) recruiting. The …


Inclusive Description Recommendations Of The Cooperative Metadata Team, University Of South Carolina Libraries Cooperative Metadata Team Apr 2024

Inclusive Description Recommendations Of The Cooperative Metadata Team, University Of South Carolina Libraries Cooperative Metadata Team

University Libraries Policies and Reports

The University of South Carolina strives to “foster access and belonging” (University of South Carolina Strategic Priories, 2023/28), and the University Libraries endeavors to be “respectful and accessible” and “responsive to changes in user needs” by investing in initiatives that “promote inclusion for and within our community” (University of South Carolina Libraries Strategic Plan, 2022/24). The USC Libraries Cooperative Metadata Team (CoMeT) seeks to support these goals by providing guidelines for creating inclusive metadata and remediating existing records. These guidelines will allow for more efficient, timely, and thoughtful processing of materials.


The Contribution Of The South Carolina Technical College System To Human Capital, Labor Force Participation, And Employment, Justin Land Apr 2024

The Contribution Of The South Carolina Technical College System To Human Capital, Labor Force Participation, And Employment, Justin Land

Senior Theses

This thesis assesses the economic impact of the South Carolina Technical College System by applying a counterfactual analysis method to the study of human capital development and labor force growth from 2010-2019. Data from the U.S. Census Bureau and the Integrated Postsecondary Education Data System (IPEDS) are used to estimate the average years of schooling attained by a South Carolinian during the period and the counterfactual average were the Technical College System to not exist. This result is then combined with probit regression models of labor force participation and employment to estimate the Technical College System’s contribution to the labor …


Decoding Implant-Related Sickness: Unraveling The Complexities Of Breast Implant Illness, Madison M. Stewart Apr 2024

Decoding Implant-Related Sickness: Unraveling The Complexities Of Breast Implant Illness, Madison M. Stewart

Senior Theses

This thesis investigates the phenomenon of breast implant illness (BII), examining its potential correlation with individual factors such as obesity and poor lifestyle habits. BII, characterized by nonspecific symptoms, is often self-diagnosed by patients influenced by social media and internet sources, leading to requests for implant removal. Conducting a comprehensive meta-analysis, the study scrutinizes existing literature to evaluate the association between BII, obesity, and lifestyle choices. Employing inclusion criteria, peer-reviewed publications are analyzed through systematic review methodology to offer insights into the interplay between BII and adiposity, exploring inflammatory mechanisms and patient behaviors like exercise and smoking. The research aims …


Innovative Retail: A Framework For The Future Of Brick-And-Mortar Retail In An Omnichannel Market, Mallory S. Strmel Apr 2024

Innovative Retail: A Framework For The Future Of Brick-And-Mortar Retail In An Omnichannel Market, Mallory S. Strmel

Senior Theses

This thesis was intended to explore the how the role of innovation in customer experience has evolved since the advent of American retail and how it can inform primarily brick-and-mortar retailers on corporate strategy formulation as they prepare for Generation Z to become the primary wielders of purchasing power in the retail landscape. A literature review featuring analysis of two best-in-class retail chains alongside their historical context revealed that many of the innovations in customer experience strategy shaped consumer behavior going forward. To investigate, I conducted a nationwide survey of Generation Z consumers to ascertain their shopping preferences and the …


Elucidating The Role Of Protease-Activated Receptor 2 In Elastase-Induced Abdominal Aortic Aneurysms, John Pitstick Apr 2024

Elucidating The Role Of Protease-Activated Receptor 2 In Elastase-Induced Abdominal Aortic Aneurysms, John Pitstick

Senior Theses

Cardiovascular diseases (CVDs) remain the leading cause of mortality in the world despite extensive research. As a type of CVD, abdominal aortic aneurysm (AAA) represents a critical medical condition characterized by the localized dilation of the abdominal aorta. Complications from aneurysm development results in catastrophic aortic rupture, which leads to mortality more than 80% of the time. As aneurysm development is typically asymptomatic, many AAAs remain untreated until they present a serious risk of rupture. Additionally, no pharmaceutical treatment exists for AAAs, with the only option being surgical intervention. Despite advancements in diagnostic methods and surgical techniques, the pathogenesis of …


‘Kazakh Means Freedom’ - Kazakh Language Policy And National Identity Before And During The Ukraine War, Mclean T. Brown Apr 2024

‘Kazakh Means Freedom’ - Kazakh Language Policy And National Identity Before And During The Ukraine War, Mclean T. Brown

Senior Theses

This thesis examines the link between language policy and national identity in Kazakhstan, tracing the relationship between the two across history and describing how they have been affected by the Ukraine War. The Kazakh government has put considerable effort into developing a national identity for contemporary Kazakhstan, but conflicting standards of production make it difficult for a cohesive, well-defined Kazakh national identity to be put forth. Through qualitative and quantitative analyses, phenomenological critical discourse analysis, and ethnographic research, this thesis strives to alleviate existing gaps in Central Asian studies research while arguing that language policy is a lens through which …


Lyraquist: Language Learning Via Music App, Vivian D'Souza, Siri Avula, Mahi Patel, Tanvi Singh, Ashley Bickham Apr 2024

Lyraquist: Language Learning Via Music App, Vivian D'Souza, Siri Avula, Mahi Patel, Tanvi Singh, Ashley Bickham

Senior Theses

Lyraquist is a new language learning mobile app that encourages the practice of a foreign language through music. Language learners can connect their Spotify Premium account to Lyraquist to listen to music in their target languages and utilize tools such as translation and vocabulary lists to facilitate language practice. Through integration with Spotify, users can import and create Spotify playlists and search the service’s entire catalog. By combining daily listening habits with several tasks associated with language learning in one place, Lyraquist hopes to be a useful language learning tool.


Facing Two Fronts: Asian Americans Grappling With Covid-19 And Xenophobic Tensions, Matthew Soos Apr 2024

Facing Two Fronts: Asian Americans Grappling With Covid-19 And Xenophobic Tensions, Matthew Soos

Senior Theses

This thesis examines the impact of COVID-19-induced discrimination against Asian Americans (AsAms) and its effects on the mental health of college-aged individuals within this demographic. The study specifically targets East and Southeast Asians due to their heightened connection with the pandemic. Data was gathered via a survey disseminated among undergraduate AsAm students at the University of South Carolina. The survey sought information on the occurrence and forms of discrimination encountered pre-pandemic and during the pandemic, alongside the mental health condition and coping mechanisms of the respondents. Moreover, participants were prompted to assess the efficacy of suggested approaches in addressing discrimination. …


Trois Chansons De Bilitis And Estampes–The Symbolist Movement And The Works Of Claude Debussy, Emma J. Devine Apr 2024

Trois Chansons De Bilitis And Estampes–The Symbolist Movement And The Works Of Claude Debussy, Emma J. Devine

Senior Theses

“Nothing is dearer than the grey song where the vague and the precise meet.” Paul Verlaine, “Art poétique”

This thesis compiles information from biographies of Claude Debussy and excerpts from performers, musicologists, music commentators, poets, and art historians, in an attempt to examine Debussy’s work through a well-rounded portrait of the artistic climate in France. This qualitative research thesis begins with a brief summary of Claude Debussy’s life, followed by a portrait of Paris at the turn of the twentieth century. The next section explores the birth of the intertwined movements of Symbolism and Impressionism, their similarities and differences, and …


Melissa A. Harness & Adam Z. Harness, A False Accountability Narrative: The Human Rights Implications Of Developed Nations Over-Testing Youth In Education, Melissa A. Harness, Adam Z. Harness Apr 2024

Melissa A. Harness & Adam Z. Harness, A False Accountability Narrative: The Human Rights Implications Of Developed Nations Over-Testing Youth In Education, Melissa A. Harness, Adam Z. Harness

The Journal of Law and Education

No abstract provided.


Over-The-Air In Personam: Purposeful Availment Through Over-The-Air Updates, Samuel R. Boyd Apr 2024

Over-The-Air In Personam: Purposeful Availment Through Over-The-Air Updates, Samuel R. Boyd

South Carolina Law Review

No abstract provided.


A Child's Right To Real Representation In Dependency Cases: A Proposal To Modify South Carolina's Child Representation System, Elizabeth G. Ward Apr 2024

A Child's Right To Real Representation In Dependency Cases: A Proposal To Modify South Carolina's Child Representation System, Elizabeth G. Ward

South Carolina Law Review

No abstract provided.


From Cough To Crip: The Development Of Codeine From A Purely Medical Substance Into A Popular Recreational Drug, Rhett C. Vaughn Apr 2024

From Cough To Crip: The Development Of Codeine From A Purely Medical Substance Into A Popular Recreational Drug, Rhett C. Vaughn

Senior Theses

The research that was conducted aimed to elicit the influence that pop culture has on recreational drug consumption. Specifically, the usage of the drug codeine has become very popular in social media among many influencers. The research focuses on the prevalence of this drug across several media platforms, alongside the growing rate of consumption globally. Research was conducted primarily through combining various databases at various organizations and this study aims to compile the data into one coherent paper regarding codeine in pop culture. While, it cannot be solely attributed to one specific outlet or influence, this study found that alongside …


The Use Of Figurative Suicidal Language By College Students And Its Impact On Mental Health And Suicide Stigma, Makayla Hooker Apr 2024

The Use Of Figurative Suicidal Language By College Students And Its Impact On Mental Health And Suicide Stigma, Makayla Hooker

Senior Theses

Using suicidal language as a hyperbole in everyday conversation has become common for college students experiencing stress. Previous research analyzed use of suicidal language on social media with the intention of finding the best way to provide help to the individuals expressing true suicidal ideation on social media but found that many people do not literally mean what they are saying when they use suicidal language. It was hypothesized that the frequency with which individuals use suicidal statements figuratively as well as the frequency with which they hear others use these statements would negatively correlate with the level of seriousness …


Preserving Viewpoint Pluralism And Democratic Principles: Florida's "Divisive Concepts" Law And Strategies For Challenging The Law's Enforcement In K-12 And Higher Education, Abigail Dallmann Apr 2024

Preserving Viewpoint Pluralism And Democratic Principles: Florida's "Divisive Concepts" Law And Strategies For Challenging The Law's Enforcement In K-12 And Higher Education, Abigail Dallmann

The Journal of Law and Education

No abstract provided.


Deciphering The Functional Connections Between The Nuclear Paraspeckle And Rad51 Homologous Recombination Proteins Using A Yeast Protein Interaction System, Eric J. Nutz Apr 2024

Deciphering The Functional Connections Between The Nuclear Paraspeckle And Rad51 Homologous Recombination Proteins Using A Yeast Protein Interaction System, Eric J. Nutz

Senior Theses

Homologous recombination (HR) is a repair pathway for DNA double-stranded breaks. Mutations in HR genes contribute to genomic instability and increase the prevalence of cancer. Exploiting HR deficiency in tumor cells has led to improved synthetic lethality outcomes. RAD51 paralogue protein complexes are known to be involved with HR. Proteomic analysis of RAD51 paralogues reveals a connection to the nuclear paraspeckle. A paraspeckle is a little-known, specialized organelle found in the interchromatin space of the nucleus in mammalian cells. Its three central protein components include SFPQ, NONO, and PSPC1. RAD51D is an HR protein shown previously to interact with SFPQ …


The Sentiments Of Drag Performers On Anti-Drag Legislation: A Thematic Analysis, Brian D. Briggs Apr 2024

The Sentiments Of Drag Performers On Anti-Drag Legislation: A Thematic Analysis, Brian D. Briggs

Senior Theses

Since 2022, at least 21 states have considered, filed, or passed legislation with the goal of banning or limiting drag performances in public spaces or in the presence of minors. These pieces of legislation seek to suppress drag performances on the grounds that they appeal to sexual interests, and they even go as far as to claim that drag performers aim to groom and assault children at their performances. These claims are baseless and vastly misrepresent the true breadth of drag as a performance art and the positive messages it promotes, as well as suggest that bias against the LGBTQ+ …


Motivations Behind The Rise And Success Of Homeopathy In India, Kavya Patchipulusu Apr 2024

Motivations Behind The Rise And Success Of Homeopathy In India, Kavya Patchipulusu

Senior Theses

Homeopathy is a form of medicine that is incredibly controversial and is often labeled as a fraudulent, placebo effect drug, that can have potentially dangerous side effects. This is the picture that is painted of homeopathy in the United States and many other countries in which these medicines are banned in distribution or highly unregulated. In contrast, India has popularized and well-integrated homeopathy into their medical systems with government backing and consistent funding towards accredited homeopathic institutions and funding hospital systems. This paper will explore the circumstances and health care dynamics of India that allowed homeopathy to gain the level …


The Individuality Of Bereavement: A Phenomenological Analysis Of Sudden Loss Trauma On Young Adults, Teaghan B. Brosokas Apr 2024

The Individuality Of Bereavement: A Phenomenological Analysis Of Sudden Loss Trauma On Young Adults, Teaghan B. Brosokas

Senior Theses

While death of a loved one or peer is likely experienced by everyone at least once in their lifetime, bereavement is far from a universalized experience. Just as no two people are alike, no two relationships are alike. Thus, no two losses breed the same after-effects. Multiple factors influence the individual characteristics of bereavement, such as mode of loss, relationship to the deceased, and possible societal barriers. This study explores the impact of a sudden unexpected death on young adults based on their relational closeness to the deceased, including plausible reasoning behind reactions and influences on post-loss adjustment. Young adults …


The Impact Of Individual Culture On Purchase Decisions Of Fast Fashion In Brazil, Lucie S. Speck Apr 2024

The Impact Of Individual Culture On Purchase Decisions Of Fast Fashion In Brazil, Lucie S. Speck

Senior Theses

Fast fashion is an emerging method of production in the apparel industry that is characterized by lower-quality materials and faster production timelines than the traditional methods of producing clothing. It is becoming a trending topic in modern business due to its negative social and environmental impact, as brands that use fast fashion production processes are constantly being criticized for inhumane labor practices and large amounts of textile waste.

This research proposes two models using a survey as its main research method. The first model determines how financial situation, collectivism as a cultural value, and education level impact whether social media …


Meme Stocks, Robinhood, And Wall Street: Retail Investors And Changing Market Dynamics, Nick Murray, Spencer Brosnan Apr 2024

Meme Stocks, Robinhood, And Wall Street: Retail Investors And Changing Market Dynamics, Nick Murray, Spencer Brosnan

Senior Theses

This thesis explores the rise of retail investors in the wake of the COVID-19 pandemic, and how they have changed the landscape of financial markets. We outline the full timeline of the GME and AMC social media craze that exemplified the power of retail investors in the market and investigate the impact the COVID-19 pandemic had on this group. Through the use of VandaTrack, a software that tracks retail investors’ trading activity, we were able to quantify the impact that retail investors have on US equities and ETFs and compare them to the market as a whole. We utilized this …