Digital Commons Network^™

Appropriateness Of Ambulatory Antibiotic Prescribing In South Carolina, 2012–2017, Pamela Bailey, Majdi N. Al-Hasan, Julie Royer, Max Habicht, Julie Ann Justo, P. Brandon Bookstaver Pharm.D., Sharon Weissman, Hana R. Winders

Faculty Publications

This population-based cohort study examines the appropriateness of antibiotic prescribing in South Carolina via aggregated pharmacy claims data matched with diagnosis codes from medical claims. Inappropriate antibiotic prescribing decreased from 30.2% in 2012 to 22.6% in 2017 (P < 0.001) and was more common in adults >40 years old.

Libraries On The Front Lines: The Imperative For Disaster-Ready Information Professionals, Feili Tu-Keefner Ph.D.

Faculty Publications

Libraries, particularly local public libraries, have evolved into hubs for community-first services, extending beyond traditional roles. Library personnel are now expected to act as first responders and crisis leaders during times such as natural disasters. This report documents the critical crisis leadership qualifications required for library personnel, identified through comprehensive research from 2015 to 2023. Findings from these situation-specific case studies call attention to the community’s needs for library services during emergencies, underscoring the requirement for LIS education to include disaster management. Continuing education (CE) is also critical in preparing information professionals for these essential roles.

Progerin Can Induce Dna Damage In The Absence Of Global Changes In Replication Or Cell Proliferation, Liza A. Joudeh, P. Logan Schuck, Nina M. Van, Alannah J. Dicintio, Jason A. Stewart, Alan S. Waldman

Faculty Publications

Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic condition characterized by features of accelerated aging, and individuals with HGPS seldom live beyond their mid-teens. The syndrome is commonly caused by a point mutation in the LMNA gene which codes for lamin A and its splice variant lamin C, components of the nuclear lamina. The mutation causing HGPS leads to production of a truncated, farnesylated form of lamin A referred to as "progerin." Progerin is also expressed at low levels in healthy individuals and appears to play a role in normal aging. HGPS is associated with an accumulation of genomic DNA …

December 4, 2024 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Strategic (Non)Disclosure: Activation And Avoidance Of Social Ties Among Women Seeking Abortion, Kathleen Broussard

Faculty Publications

The increased politicization of sexual and reproductive health has created barriers to medically necessary care. In absence of formal health care, social ties become critical sources of information and resources, yet the disclosure of stigmatized health needs carries significant risk. How do people navigate the risks and benefits of disclosure when seeking care for stigmatized needs? Drawing on original survey data (N = 153) and in-depth interviews (N = 55) with women who attempted a self-managed abortion, I first describe the distinct roles of weak and strong ties in women’s health-seeking experiences. I then demonstrate how both partial disclosure and …

Sexual Orientation, Gender Identity And Virologic Failure Among People With Hiv: A Cohort Study In All Of Us Research Program, Fanghui Shi, Ruilie Cai, Buwei He, Xiaoming Li Ph.D., Xueying Yang Ph.D., Sharon Weissman, Bankole Olatosi Ph.D., Jiajia Zhang Ph.D.

Faculty Publications

Background: Sexual and gender minorities (SGMs) are at higher risk of HIV incidence compared to their heterosexual cisgender counterparts. Despite the high HIV disease burden among SGMs, there was limited data on whether they are at higher risk of virologic failure, which may lead to potential disease progression and increased transmission risk. The All of Us (AoU) Research Program, a national community-engaged program aiming to improve health and facilitate health equity in the United States by partnering with one million participants, provides a promising resource for identifying a diverse and large volunteer TGD cohort. Leveraging various data sources available through …

Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude

Faculty Publications

Triple-negative breast cancers (TNBC) are treated primarily by chemotherapy and lack clinically validated therapeutic targets. In particular, inhibitors of the PI3K/AKT/mTOR pathway, abnormally activated in many breast cancers, failed to achieve clinical efficacy in TNBC due to the development of adaptive drug resistance, which is largely driven by the transcriptomic plasticity of TNBC. Expression of CDK8/19 Mediator kinases that control transcriptional reprogramming correlates with relapse-free survival and treatment failure in breast cancer patients, including TNBC. We now investigated how CDK8/19 inhibitors affect the growth of TNBC tumors and their response to mTOR and AKT inhibitors. In contrast to the effects …

The Daily Gamecock: November 2024, University Of South Carolina, Office Of Student Media

November

No abstract provided.

An Analysis Of Racial Tasking And Other Sport Management Theories Through The Lived Experiences Of Black College Football Coaches, Trevor Bopp, Robert Turick

Journal of Issues in Intercollegiate Athletics

The purpose of this study was to explore Black coaches’ (N = 17) perceptions of the academic research that purports to shed light on their experiences in college football. In sharing their lived experiences, coaches discussed the racial inequalities they have and continue to overcome to enter, remain, and advance in coaching; considered the existence and influence of racial tasking; and provided their thoughts on sport management research. In doing so, they remarked about many of the racialized barriers and disparate outcomes which we have hypothesized, analyzed, interpreted, and written about in our academic work. Implications from this study provide …

Framing Foreignness In Sports: The Effect Of Text And Image Frames On Attitudes Toward Australian College Punters, James Bingaman

Journal of Issues in Intercollegiate Athletics

In recent years, there has been an influx of Australian college punters receiving significant media attention. This media coverage often emphasizes these athlete’s “foreignness” by relying on cultural stereotypes. Existing research has shown that the framing of athletes – both text and image frames – can influence individuals’ attitudes and perceptions. Using a 2 x 3 (two textual frames x three visual frames) experimental design, this study sought to test the effects of “foreignness” framing on attitudes toward Australian punters and punters more broadly. The results offer several directions for sports media scholars to examine media effects related to the …

“We Need To Do More” To “This Is All Bullsh**” : A Continuum Of Race-Related Social Media Activism In College Athletics, Natalie N. Bunch, Lauren Beasley, Beth Cianfrone

Journal of Issues in Intercollegiate Athletics

National Collegiate Athletic Association (NCAA) member institutions have addressed social issues, such as racial justice, via team or athletic department social media platforms. Often the social media strategy is managed by a content creator within the athletic department. However, coaching staff members may be concerned with what is posted to team or athletic department accounts because of the public facing nature of their job, their use of social media in recruitment efforts, and their role in creating a positive environment for current athletes. We surveyed 128 coaches across divisions to determine perceptions of their athletic department’s race-related activism on social …

November 6, 2024 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Share Your Story; Good News From Sc Libraries, Virginia Cononie

South Carolina Libraries

Welcome to the third edition

of Share Your Story, where I am deeply grateful to present over 75 inspiring library stories from across our great state. Each story is a testament to the essential role libraries play in impacting communities and the lives of those they serve.

As you explore this collection, you'll discover a rich tapestry of experiences from school, public, and academic libraries. From community gardens to therapy dog visits, activities fostering the love of reading to donor funds well spent—these stories showcase the diverse ways libraries enrich our local communities.

These stories not only demonstrate Good News …

How To Improve Your Teen Space, Alex Bishop

South Carolina Libraries

No abstract provided.

Revitalizing The Curriculum Collection: A Collaborative Partnership Approach, Kimberly T. Foster, Eric Resnis

South Carolina Libraries

As K-12 education has increasingly focused on standardized testing, university curriculum centers have had to adjust their holding to offer more curricula-focused material. These collections can be vital for the development of pre-service teachers, who often need access to the learning materials that they will later use. This article explores the steps taken by a university library to revitalize a curriculum collection in order to offer more curriculum-based holdings for pre-service teachers to use.

Identifying Ordinal Categories For The Water Insecurity Experiences Scales, Edward A. Frongillo Jr., Hilary J. Bethancourt, Joshua D. Miller, Sera L. Young, The Household Water Insecurity Experiences Scales (Hwise)-Research Coordination Network (Rcn)

Faculty Publications

The Household Water Insecurity Experiences (HWISE) and Individual Water Insecurity Experiences (IWISE) Scales are globally suitable tools for comparably measuring water insecurity experiences among households and adults, respectively. The potential range for HWISE and IWISE scores is 0–36. When the WISE Scales were first published, scores of 12 and higher were considered indicative of water insecurity, but additional cut-points are needed to provide more nuanced insights. We therefore sought to develop a practical set of cut-points for the WISE Scales using HWISE data from 13 sites across 12 countries (n = 3,293) and nationally representative samples of IWISE data …

How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton Ma, Lmsw, Simone Kabarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.

Faculty Publications

Background: The concept of health literacy (HL) is constantly evolving, and social determinants of health (SDoH) have been receiving considerable attention in public health scholarship. Since a 1-size-fits-all approach for HL fails to account for multiple contextual factors and as a result poses challenges in improving literacy levels, there is a need to develop a deeper understanding of the current state of HL and digital health literacy (DHL) research. Objective: This study examined scholars’ conceptualization and scope of work focused on HL and DHL. Methods: Using a search string, investigators (N=2042) focusing on HL, DHL, or both were identified from …

How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? A Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton, Simon Kavarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent Rd, Mph, Cscs, Cissn, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.

Publications

Background: The concept of health literacy (HL) is constantly evolving, and social determinants of health (SDoH) have been receiving considerable attention in public health scholarship. Since a 1-size-fits-all approach for HL fails to account for multiple contextual factors and as a result poses challenges in improving literacy levels, there is a need to develop a deeper understanding of the current state of HL and digital health literacy (DHL) research.

Objective: This study examined scholars’ conceptualization and scope of work focused on HL and DHL.

Methods: Using a search string, investigators (N=2042) focusing on HL, DHL, or both were identified from …

Investigating Ticket Price Determination Of Collegiate Athletics: Insights From Pricing Professionals In Non-Football Bowl Subdivision Schools, Jason D. Reese, Yang Xu

Journal of Issues in Intercollegiate Athletics

This study aims to investigate how ticket prices are set in Division I (DI) college athletics, how the individuals making pricing decisions perceive the purpose of athletics, what objectives pricing managers are trying to achieve with both revenue and non-revenue sports, and the factors that influence how the final price is set. Structured interviews were conducted with 12 athletic department external operations staff from 12 non-FBS DI institutions, representing seven different conferences. Results showed that price is determined through either a bottom-up hierarchical model or a committee-based model. Patronage-Oriented objectives were shown to dominate the pricing strategy in non-FBS programs, …

Evaluation And Lessons Learned From The Dissemination And Implementation Science Scholars Program In The National Cancer Prevention And Control Research Network, Daniela B. Friedman, Cam Escoffery, Elaine H. Morrato, Cynthia A. Thomson, Courtney N. Petagna, Freda Allyson Hucek, Mary Wangen, Aubrey Villalobos, James R. Hébert Scd, Samuel Noblet, Mayank Sakhuja, David O. Garcia, Jennifer L. Cruz, Stephanie B. Wheeler

Faculty Publications

Background:

The Centers for Disease Control and Prevention (CDC)-funded Cancer Prevention and Control Research Network (CPCRN) has been a leader in cancer-related dissemination & implementation (D&I) science. Given increased demand for D&I research, the CPCRN Scholars Program launched in 2021 to expand the number of practitioners, researchers, and trainees proficient in cancer D&I science methods. Methods:

The evaluation was informed by a logic model and data collected through electronic surveys. Through an application process (baseline survey), we assessed scholars’ competencies in D&I science domains/subdomains, collected demographic data, and asked scholars to share proposed project ideas. We distributed an exit survey …

Garnet & Black: Fall 2024, University Of South Carolina, Office Of Student Media

Garnet & Black Magazine

No abstract provided.

The Daily Gamecock: October 2024, University Of South Carolina, Office Of Student Media

October

No abstract provided.

How Has Health Literacy And Digital Health Literacy Scholarship Evolved? A Global, Qualitative Study, Brooks Yelton Ma, Lmsw, Mayank Sakhuja, Simone Kavarana, Lauren Schaurer, Michelle Angelique Arent, Lorie Donelle Phd, Rn, Fcan, Mark M. Macauda, Samuel Noblet, Daniela B. Friedman

Publications

Health literacy (HL) is a key social determinant of health (SDoH) and is of increasing importance in public health research and intervention for improved health outcomes. Definitions of HL and digital health literacy (DHL) have evolved over time as the field has expanded conceptualization from an individual focus to the broader community and organizational levels. Careful consideration of HL and DHL for a variety of contexts and audiences is critical given increased global adoption of digital technologies and responses to emerging public health challenges. This study aimed to capture researchers' conceptualizations of HL/DHL and their motivations to engage in this …

October 9, 2024 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

Disclosure Patterns Of Opioid Use Disorders In Perinatal Care During The Opioid Epidemic On X From 2019 To 2021: Thematic Analysis, Dezhi Wu, Minnie Ng, Saborny Sen Gupta, Phyllis Raynor Phd, Aprn, Pmhnp-Bc, Youyou Tao, Yang Ren, Peiyin Hung, Shan Qiao, Jiajia Zhang, Jennifer Fillo, Xiaoming Li, Constance Guille, Kacey Eichelberger, Bankole Olatosi

Publications

BACKGROUND: In 2021, the United States experienced a 14% rise in fatal drug overdoses totaling 106,699 deaths, driven by harmful opioid use, particularly among individuals in the perinatal period who face increased risks associated with opioid use disorders (OUDs). Increased concerns about the impacts of escalating harmful opioid use among pregnant and postpartum persons are rising. Most of the current limited perinatal OUD studies were conducted using traditional methods, such as interviews and randomized controlled trials to understand OUD treatment, risk factors, and associated adverse effects. However, little is known about how social media data, such as X, formerly known …

Devices And Dining: A Cross-Cultural Analysis Of Mobile Device Use In Italian And American Restaurants, O'Malley Jenkins

Senior Theses

The field of technology ethics has seen increasing growth and interest over the years. Many have begun to consider the impacts of technology’s use and whether it is being employed in a healthy manner by users. However, there has been limited investigation into whether the ways in which technology use varies across cultures. This study begins to address this gap by researching Italian and American device usage in fast food settings. Non-participant naturalistic observations were used to record data for 89 Italian and 88 American customers of fast food restaurants. Analysis of the collected data indicates that Americans use their …

Efficacy Of, And Barriers To, Treatment Options For Pans/Pandas, Kayla E. Pray

Senior Theses

Background: PANS/PANDAS are pediatric autoimmune disorders that cause an acute-onset of OCD-like symptoms and/or severe restricted eating, as well as anxiety, irritation, deterioration of fine motor skills, hyperactivity, and other psychiatric symptoms. An estimated 1-2% of the pediatric population is affected. Currently, there is little research published on the treatment options for PANS/PANDAS and there is no evidence-based consensus on the best treatment option.

Purpose: This study aimed to discover the efficacy of, and barriers to, available treatment options for PANS/PANDAS.

Methods: A convenience sample of individuals diagnosed with PANS/PANDAS or their parent/caregiver was recruited anonymously through Facebook support groups. …

Protecting Coastal Communities And Marine Biodiversity Under The Coastal Zone Management Act, Eric V. Hull

South Carolina Law Review

No abstract provided.

Enhancing Inclusivity In Primary Care On A College Campus, Amanda Finkle Plyler

Doctor of Nursing Practice Scholarly Projects

Problem Statement: Individuals who identify as lesbian, gay, bisexual, transgender, and queer or questioning (LGBTQ+) face higher health disparities and are less likely to seek healthcare due to fear of being misgendered or judged by staff. Purpose: The purpose of this DNP project was to implement an intervention for college students seeking care at Student Health Services (SHS) that includes a question addressing preferred pronouns during establishment of care, creating the opportunity for staff to address patients appropriately and to provide gender-affirming care. Method(s): A pre and post intervention patient satisfaction survey related to sexual orientation and gender identity (SOGI), …

Identifying Adolescent Depression In The Public School System, Laura Lee Griffith

Doctor of Nursing Practice Scholarly Projects

Problem Statement: Twenty percent of United States adolescents experience major depression at some point. Elevated school dropout rates, substance abuse, chronic disease, mortality and morbidity rates, and impaired growth remain because 60 % of adolescents with unidentified depression do not receive treatment. Purpose: This evidence-based project identified adolescents aged 16-19 in a South Carolina high school who had symptoms of depression. Counseling and resource information were provided for students with scores of 10 or greater, or thoughts of self-harm on the PHQ-9. Method: Students were screened using the PHQ-9. Data was organized in Excel and analyzed using the T-tests and …