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September 8, 2021 Faculty Senate Minutes, University Of South Carolina
September 8, 2021 Faculty Senate Minutes, University Of South Carolina
Faculty Senate
No abstract provided.
Examining Associations Between Knowledge And Vaccine Uptake Using The Human Papillomavirus Knowledge Questionnaire (Hpv-Kq), Sayward Harrison, Valerie Yelverton, Yunfei Wang, Jan Ostermann, Laura J. Fish, Charnetta L. Williams, Lavanya Vasudevan, Emmanuel B. Walter
Examining Associations Between Knowledge And Vaccine Uptake Using The Human Papillomavirus Knowledge Questionnaire (Hpv-Kq), Sayward Harrison, Valerie Yelverton, Yunfei Wang, Jan Ostermann, Laura J. Fish, Charnetta L. Williams, Lavanya Vasudevan, Emmanuel B. Walter
Faculty Publications
Objectives: Understanding the relationship between human papillomavirus (HPV) knowledge and vaccination behavior is important to inform public health interventions, yet few validated HPV knowledge scales exist. This study describes development of the Human Papillomavirus Knowledge Questionnaire (HPV-KQ) and its validation with parents residing in the southern United States (US). Methods: Drawing on previously published measures, we developed the 13-item HPV-KQ and administered the scale via Web-based survey to parents (N=1105) of adolescents ages 9 to 17 years. Dimensionality, internal consistency, model fit, and predictive validity were assessed. Results: The scale was bidimensional. One factor captured general HPV knowledge, and the …
Examining Associations Between Knowledge And Vaccine Uptake Using The Human Papillomavirus Knowledge Questionnaire (Hpv-Kq), Sayward Harrison, Valerie Yelverton, Jan Ostermann Ph.D., Laura J. Fish, Charnetta L. Williams, Lavanya Vasudevan, Emmanuel B. Walter
Examining Associations Between Knowledge And Vaccine Uptake Using The Human Papillomavirus Knowledge Questionnaire (Hpv-Kq), Sayward Harrison, Valerie Yelverton, Jan Ostermann Ph.D., Laura J. Fish, Charnetta L. Williams, Lavanya Vasudevan, Emmanuel B. Walter
Faculty Publications
Objectives: Understanding the relationship between human papillomavirus (HPV) knowledge and vaccination behavior is important to inform public health interventions, yet few validated HPV knowledge scales exist. This study describes development of the Human Papillomavirus Knowledge Questionnaire (HPV-KQ) and its validation with parents residing in the southern United States (US). Methods: Drawing on previously published measures, we developed the 13-item HPV-KQ and administered the scale via Web-based survey to parents (N=1105) of adolescents ages 9 to 17 years. Dimensionality, internal consistency, model fit, and predictive validity were assessed. Results: The scale was bidimensional. One factor captured general HPV knowledge, and the …
September 1, 2021 General Faculty Minutes, University Of South Carolina
September 1, 2021 General Faculty Minutes, University Of South Carolina
Faculty Senate
No abstract provided.
Including Latinx Communities In Academic Libraries: A Theoretical Approach To Information Access, Andrew Wakelee, Kim M. Thompson
Including Latinx Communities In Academic Libraries: A Theoretical Approach To Information Access, Andrew Wakelee, Kim M. Thompson
Faculty Publications
While more Latinx students continue to enroll in higher education, physical, intellectual, and socio-cultural barriers to information may continue to impede their success and inclusion. A tripartite theoretical model that examines physical, intellectual, and socio-cultural information access provides insights for academic libraries to better meet Latinx students’ information needs and include them in campus life. This paper gives an overview of the theoretical framework along with practical steps libraries can take to improve information equity.
What Factors Influence Hiv Testing? Modeling Preference Heterogeneity Using Latent Classes And Class-Independent Random Effects, Jan Ostermann Ph.D., Brian P. Flaherty, Derek S. Brown, Bernard Njau, Amy M. Hobbie, Tara B. Mtuy, Max Masnick, Axel C. Mühlbacher, Nathan M. Thielman
What Factors Influence Hiv Testing? Modeling Preference Heterogeneity Using Latent Classes And Class-Independent Random Effects, Jan Ostermann Ph.D., Brian P. Flaherty, Derek S. Brown, Bernard Njau, Amy M. Hobbie, Tara B. Mtuy, Max Masnick, Axel C. Mühlbacher, Nathan M. Thielman
Faculty Publications
Efforts to eliminate the HIV epidemic will require increased HIV testing rates among high-risk populations. To inform the design of HIV testing interventions, a discrete choice experiment (DCE) with six policy-relevant attributes of HIV testing options elicited the testing preferences of 300 female barworkers and 440 male Kilimanjaro mountain porters in northern Tanzania. Surveys were administered between September 2017 and July 2018. Participants were asked to complete 12 choice tasks, each involving first- and second-best choices from 3 testing options. DCE responses were analyzed using a random effects latent class logit (RELCL) model, in which the latent classes summarize common …
Dependence On Humidity And Aerosol Composition Of The Gas-Particle Partitioning Of Weakly And Moderately Polar Vocs, Jeonghyeon Ahn, Guiying Rao, Eric P. Vejerano
Dependence On Humidity And Aerosol Composition Of The Gas-Particle Partitioning Of Weakly And Moderately Polar Vocs, Jeonghyeon Ahn, Guiying Rao, Eric P. Vejerano
Faculty Publications
Volatile organic compounds (VOCs) dominate the class of pollutants that accumulate in the atmosphere and indoors. Assessing the gas-particle partitioning of VOCs is important to determine their fate, transport, and adverse health impacts. This work is a companion to our earlier study on the temperature dependence of VOC partitioning. Here, we report our measurement of the gas-particle partition coefficient (Kp) for weakly polar (trichloroethylene, TCE) and moderately polar (n-butanol, n-BuOH) VOCs under varying relative humidity (RH) levels onto organic and inorganic aerosols. Kp of TCE was four to five orders of magnitude lower than those …
Creation Of A Cip Method For The Heat Exchangers At Rolls-Royce, Melanie Howe, Austin Williams, Caroline Dempsey, Bethany Fralick
Creation Of A Cip Method For The Heat Exchangers At Rolls-Royce, Melanie Howe, Austin Williams, Caroline Dempsey, Bethany Fralick
Journal of the South Carolina Academy of Science
Rolls-Royce produces various engines which must be tested prior to their distribution to ensure a high-quality product. The manufacturing plant contains four test cells where the engines can be subjected to high levels of torque and extreme temperatures. A heat exchanger is necessary in this testing system and over time, unwanted waste accumulates on the system’s plates. The team is tasked with developing and implementing a system mounted on a mobile cart which can provide data to determine whether the plates need to be cleaned. For this cleaning system to work, it must fully saturate the heat exchanger in cleaning …
Political Socialization In Teenagers: To What Extent Are Socialization Agents Associated With The Political Dispositions Of Adolescents Aged 14–18 ?, Luci Green
Journal of the South Carolina Academy of Science
No abstract provided.
The Relationship Between Personality Traits And The Strength Of Anxiety Symptoms, Kate Soderlund
The Relationship Between Personality Traits And The Strength Of Anxiety Symptoms, Kate Soderlund
Journal of the South Carolina Academy of Science
No abstract provided.
Cardiovascular Health Trajectories And Elevated C-Reactive Protein: The Cardia Study, Jonathan J. Ruiz-Ramie, Jacob L. Barber, Donald M. Lloyd-Jones, Myron D. Gross, Jamal S. Rana, Stephen Sidney, David R. Jacobs Jr., Abbi D. Lane-Cordova, Mark A. Sarzynski Facsm
Cardiovascular Health Trajectories And Elevated C-Reactive Protein: The Cardia Study, Jonathan J. Ruiz-Ramie, Jacob L. Barber, Donald M. Lloyd-Jones, Myron D. Gross, Jamal S. Rana, Stephen Sidney, David R. Jacobs Jr., Abbi D. Lane-Cordova, Mark A. Sarzynski Facsm
Faculty Publications
Background
The relationship between long‐term cardiovascular health (CVH) patterns and elevated CRP (C‐reactive protein) in late middle age has yet to be investigated. We aimed to assess this relationship.Methods and Results
Individual CVH components were measured in 4405 Black and White men and women (aged 18–30 years at baseline) in the CARDIA (Coronary Artery Risk Development in Young Adults) study at 8 examinations over 25 years. CRP was measured at 4 examinations (years 7, 15, 20, and 25). Latent class modeling was used to identify individuals with similar trajectories in CVH from young adulthood to middle age. Multivariable Poisson …Knowledge Assessment Of Anti-Snake Venom Among Healthcare Practitioners In Northern Nigeria, Auwal A. Bala, Abubakar Jatau, Ismaeel Yunusa Ph.D., Mustapha Mohammed, Al-Kassim H. Mohammed, Abubakar M. Isa, Abubakar S. Wada, Kabiru A. Gulma, Inuwa Bello, Sani Malami
Knowledge Assessment Of Anti-Snake Venom Among Healthcare Practitioners In Northern Nigeria, Auwal A. Bala, Abubakar Jatau, Ismaeel Yunusa Ph.D., Mustapha Mohammed, Al-Kassim H. Mohammed, Abubakar M. Isa, Abubakar S. Wada, Kabiru A. Gulma, Inuwa Bello, Sani Malami
Faculty Publications
Introduction: Anti-snake venom (ASV) is the standard therapy for the management of snakebite envenoming (SBE). Therefore, the knowledge of ASV among healthcare practitioners (HCPs) is essential for achieving optimal clinical outcomes in snakebite management. This study aimed to assess knowledge of ASV among the HCPs in northern Nigeria.
Methods: We conducted a cross-sectional study involving eligible HCPs from different healthcare settings in northern Nigeria. The participants were recruited into the study using a combination of online (via Google Form) and face-to-face paper-based survey methods. The ASV knowledge of the respondents was measured using a validated anti-snake venom knowledge assessment tool …
Normalization Of Muscle Strength Measurements In The Assessment Of Cardiometabolic Risk Factors In Adolescents, Tiago Rodrigues De Lima, Xuemei Sui M.D., M.P.H., Ph.D., Diego Augusto Santos Silva
Normalization Of Muscle Strength Measurements In The Assessment Of Cardiometabolic Risk Factors In Adolescents, Tiago Rodrigues De Lima, Xuemei Sui M.D., M.P.H., Ph.D., Diego Augusto Santos Silva
Faculty Publications
Muscle strength (MS) has been associated with cardiometabolic risk factors (CMR) in adolescents, however, the impact attributed to body size in determining muscle strength or whether body size acts as a confounder in this relationship remains controversial. We investigated the association between absolute MS and MS normalized for body size with CMR in adolescents. This was a cross-sectional study comprising 351 adolescents (44.4% male; 16.6 ± 1.0 years) from Brazil. MS was assessed by handgrip and normalized for body weight, body mass index (BMI), height, and fat mass. CMR included obesity, high blood pressure, dyslipidemia, glucose imbalance, and high inflammation …
Covid-19 Disrupted Provision And Utilization Of Health And Nutrition Services In Uttar Pradesh, India: Insights From Service Providers, Household Phone Surveys, And Administrative Data, Phuong H. Nguyen, Shivani Kachwaha, Anjali Pant, Lan M. Tran, Monika Walia, Sebanti Ghosh, Praveen K. Sharma, Jessica Escobar-Alegria, Edward A. Frongillo Jr., Purnima Menon, Rasmi Avula
Covid-19 Disrupted Provision And Utilization Of Health And Nutrition Services In Uttar Pradesh, India: Insights From Service Providers, Household Phone Surveys, And Administrative Data, Phuong H. Nguyen, Shivani Kachwaha, Anjali Pant, Lan M. Tran, Monika Walia, Sebanti Ghosh, Praveen K. Sharma, Jessica Escobar-Alegria, Edward A. Frongillo Jr., Purnima Menon, Rasmi Avula
Faculty Publications
BACKGROUND: The coronavirus (COVID-19) pandemic may substantially affect health systems, but little primary evidence is available on disruption of health and nutrition services. OBJECTIVES: This study aimed to 1) determine the extent of disruption in provision and utilization of health and nutrition services induced by the pandemic in Uttar Pradesh, India; and 2) identify how adaptations were made to restore service provision in response to the pandemic. METHODS: We conducted longitudinal surveys with frontline workers (FLWs, n = 313) and mothers of children < 2 y old (n = 659) in December 2019 (in-person) and July 2020 (by phone). We also interviewed block-level managers and obtained administrative data. We examined changes in service provision and utilization using Wilcoxon matched-pairs signed-rank tests. RESULTS: Compared with prepandemic, service provision reduced substantially during lockdown (83-98 percentage points, pp), except for home visits and take-home rations (∼ 30%). Most FLWs (68%-90%) restored service provision in July 2020, except for immunization and hot cooked meals (< 10%). Administrative data showed similar patterns of disruption and restoration. FLW fears, increased workload, inadequate personal protective equipment (PPE), and manpower shortages challenged service provision. Key adaptations made to provide services were delivering services to beneficiary homes (∼ 40%-90%), social distancing (80%), and using PPE (40%-50%) and telephones for communication (∼ 20%). On the demand side, service utilization reduced substantially (40-80 pp) during the lockdown, but about half of mothers received home visits and food supplementation. Utilization for most services did not improve after the lockdown, bearing the challenges of limited travel (30%), nonavailability of services (26%), and fear of catching the virus when leaving the house (22%) or meeting service providers (14%). CONCLUSIONS: COVID-19 disrupted the provision and use of health and nutrition services in Uttar Pradesh, India, despite adaptations to restore services. Strengthening logistical support, capacity enhancement, performance management, and demand creation are needed to improve service provision and utilization during and post-COVID-19.
Odt Flow: Extracting, Analyzing, And Sharing Multi-Source Multi-Scale Human Mobility, Zhenlong Li, Xiao Huang, Tao Hu, Huan Ning, Xinyue Ye, Binghu Huang, Xiaoming Li
Odt Flow: Extracting, Analyzing, And Sharing Multi-Source Multi-Scale Human Mobility, Zhenlong Li, Xiao Huang, Tao Hu, Huan Ning, Xinyue Ye, Binghu Huang, Xiaoming Li
Faculty Publications
In response to the soaring needs of human mobility data, especially during disaster events such as the COVID-19 pandemic, and the associated big data challenges, we develop a scalable online platform for extracting, analyzing, and sharing multi-source multi-scale human mobility flows. Within the platform, an origin-destination-time (ODT) data model is proposed to work with scalable query engines to handle heterogenous mobility data in large volumes with extensive spatial coverage, which allows for efficient extraction, query, and aggregation of billion-level origin-destination (OD) flows in parallel at the server-side. An interactive spatial web portal, ODT Flow Explorer, is developed to allow users …
Explicit And Implicit Attitudes Towards Prisoners: The Impact Of Level Of Contact, Samantha Peka
Explicit And Implicit Attitudes Towards Prisoners: The Impact Of Level Of Contact, Samantha Peka
USC Aiken Psychology Theses
Objective: Prisoners and ex-prisoners face overt and covert forms of prejudice and discrimination (e.g., barriers to employment, housing, healthcare, voting rights). Fueling this prejudice and discrimination are implicit and explicit negative attitudes towards prisoners. Negative implicit and explicit attitudes play a major role into successful reintegration into society post-release. The purpose of this study was to examine if exposure to prisoners/ex-prisoners and political affiliation influence implicit and explicit attitudes.
Method: Participants (n = 73) completed a prisoner Implicit Association Test (IAT). Then, participants completed the explicit measures, Social Distance Scale, Attribute Questionnaire, Belief in Redeemability, Attitudes Towards Prisoners, and Prosociality …
A Copper-Covered Wooden Object From The Wateree Valley, Adam King, David H. Dye
A Copper-Covered Wooden Object From The Wateree Valley, Adam King, David H. Dye
Faculty & Staff Publications
No abstract provided.
Legacy - August 2021, South Carolina Institute Of Archaeology And Anthropology--University Of South Carolina
Legacy - August 2021, South Carolina Institute Of Archaeology And Anthropology--University Of South Carolina
SCIAA Magazine - Legacy & PastWatch
Contents:
South Carolina Lt. Governor Pamela S. Evette Honors Tommy Charles with the Order of the Palmetto…p. 1
Director’s Notes…p. 2
Ground Penetrating Radar Survey at the Wesley United Methodist Church, Beaufort, South Carolina…p. 8
A Copper-Covered Wooden Object from the Wateree Valley…p. 9
Remote Sensing at the Adamson Mounds Site (38KE11), Kershaw County, South Carolina…p. 12
Numismatic History of the Charlesfort/Santa Elena Site: The U.S. Marine Corps Maneuver Grounds…p. 14
Just How Far Did Soto Go? …p. 19
Conservation and Documentation of a Significant Camden Battlefield Collection…p. 22
Full Circle: John Bartlam’s Porcelain Returns to the Carolinas…p. 25
New …
Play, Chat, Date, Learn, And Suffer? Merton’S Law Of Unintended Consequences And Digital Technology Failures, Mark Rosenbaum, Gabby Walters, Karen Edwards J.D., Claudia Gonzalez, Germán Contreras Ramírez
Play, Chat, Date, Learn, And Suffer? Merton’S Law Of Unintended Consequences And Digital Technology Failures, Mark Rosenbaum, Gabby Walters, Karen Edwards J.D., Claudia Gonzalez, Germán Contreras Ramírez
Faculty Publications
No abstract provided.
The Impact Of Micro Porous Layer On Liquid Water Evolution Inside Pemfc Using Lattice Boltzmann Method, Mitchell Sepe, P. Satjaritanun, I. V. Zenyuk, N. Tippayawong, Sirivatch Shimpalee
The Impact Of Micro Porous Layer On Liquid Water Evolution Inside Pemfc Using Lattice Boltzmann Method, Mitchell Sepe, P. Satjaritanun, I. V. Zenyuk, N. Tippayawong, Sirivatch Shimpalee
Faculty Publications
Proton exchange membrane fuel cells (PEMFCs) require a gas diffusion layer to aid in fuel transport to the catalyst sites. A microporous layer (MPL) is often added to the GDL to improve liquid saturation inside gas diffusion media. In this work, the lattice Boltzmann method was applied to four GDL samples with the addition of an MPL. Three injection orientations were used to study liquid evolution through the samples. Each orientation used four different injection pressures, ranging from 5,000 Pa to 8,000 Pa. Saturation data for GDL samples with and without an MPL were compared. Results showed that when adding …
Exploring How Exposure To Truth And State-Sponsored Anti-Tobacco Media Campaigns Affect Smoking Disparities Among Young Adults Using A National Longitudinal Dataset, 2002-2017, David C. Colston, Yanmei Xie, Jim Thrasher Ph.D.,Ma. Ms, Sherry Emery, Megan E. Patrick, Andrea R. Titus, Micheal R. Elliot, Nancy L. Fleischer
Exploring How Exposure To Truth And State-Sponsored Anti-Tobacco Media Campaigns Affect Smoking Disparities Among Young Adults Using A National Longitudinal Dataset, 2002-2017, David C. Colston, Yanmei Xie, Jim Thrasher Ph.D.,Ma. Ms, Sherry Emery, Megan E. Patrick, Andrea R. Titus, Micheal R. Elliot, Nancy L. Fleischer
Faculty Publications
Background. Little is known regarding long-term impacts of anti-tobacco media campaigns on youth smoking and related disparities in the United States. Methods. We examined longitudinal cohort data from Monitoring the Future (MTF) between 2000 and 2017 in modified Poisson regression models to understand the long-term impacts of televised Truth and state-sponsored ad campaign exposure at baseline (age 18) on first cigarette and daily smoking initiation 1 to 2 years later (at modal ages 19/20). We also used additive interactions to test for potential effect modification between campaign exposure and smoking outcomes by sex, race/ethnicity, and parental educational attainment. Results. We …
Measuring Global Multi-Scale Place Connectivity Using Geotagged Social Media Data, Zhenlong Li, Xiao Huang, Xinyue Ye, Yuqin Jiang, Yago Martin, Huan Ning, Michael E. Hodgson, Xiaoming Li
Measuring Global Multi-Scale Place Connectivity Using Geotagged Social Media Data, Zhenlong Li, Xiao Huang, Xinyue Ye, Yuqin Jiang, Yago Martin, Huan Ning, Michael E. Hodgson, Xiaoming Li
Faculty Publications
Shaped by human movement, place connectivity is quantified by the strength of spatial interactions among locations. For decades, spatial scientists have researched place connectivity, applications, and metrics. The growing popularity of social media provides a new data stream where spatial social interaction measures are largely devoid of privacy issues, easily assessable, and harmonized. In this study, we introduced a global multi-scale place connectivity index (PCI) based on spatial interactions among places revealed by geotagged tweets as a spatiotemporal-continuous and easy-to-implement measurement. The multi-scale PCI, demonstrated at the US county level, exhibits a strong positive association with SafeGraph population movement records …
Measuring Global Multi-Scale Place Connectivity Using Geotagged Social Media Data, Zhenlong Li, Xiao Huang, Yuqin Jiang, Yago Martin, Huan Ning, Michael E. Hodgson, Xiaoming Li
Measuring Global Multi-Scale Place Connectivity Using Geotagged Social Media Data, Zhenlong Li, Xiao Huang, Yuqin Jiang, Yago Martin, Huan Ning, Michael E. Hodgson, Xiaoming Li
Faculty Publications
Shaped by human movement, place connectivity is quantified by the strength of spatial interactions among locations. For decades, spatial scientists have researched place connectivity, applications, and metrics. The growing popularity of social media provides a new data stream where spatial social interaction measures are largely devoid of privacy issues, easily assessable, and harmonized. In this study, we introduced a global multi-scale place connectivity index (PCI) based on spatial interactions among places revealed by geotagged tweets as a spatiotemporal-continuous and easy-to-implement measurement. The multi-scale PCI, demonstrated at the US county level, exhibits a strong positive association with SafeGraph population movement records …
Medication Adherence Reminder System For Virtual Home Assistants: Mixed Methods Evaluation Study, Cythnia F. Corbett, Elizabeth M. Combs, Peyton S. Chandarana, Isabel Stringfellow, Karen Worthy, Thien Nguyen, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Jason M. O'Kane
Medication Adherence Reminder System For Virtual Home Assistants: Mixed Methods Evaluation Study, Cythnia F. Corbett, Elizabeth M. Combs, Peyton S. Chandarana, Isabel Stringfellow, Karen Worthy, Thien Nguyen, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Jason M. O'Kane
Faculty Publications
Background: Medication nonadherence is a global public health challenge that results in suboptimal health outcomes and increases health care costs. Forgetting to take medicines is one of the most common reasons for unintentional medication nonadherence. Research findings indicate that voice-activated virtual home assistants, such as Amazon Echo and Google Home devices, may be useful in promoting medication adherence.
Objective: This study aims to create a medication adherence app (skill), MedBuddy, for Amazon Echo devices and measure the use, usability, and usefulness of this medication-taking reminder skill.
Methods: A single-group, mixed methods, cohort feasibility study was conducted with women who took …
Andrographolide Attenuates Gut-Brain-Axis Associated Pathology In Gulf War Illness By Modulating Bacteriome-Virome Associated Inflammation And Microglia-Neuron Proinflammatory Crosstalk, Punnag Saha, Peter T. Skidmore, Larinda A. Holland, Ayan Mondal, Dipro Bose, Ratanesh K. Seth, Kimberly Sullivan, Patricia A. Janulewicz, Ronnie Horner, Nancy Klimas, Mitzi Nagarkatti, Prakash Nagarkatti, Efrem S. Lim, Saurabh Chatterjee
Andrographolide Attenuates Gut-Brain-Axis Associated Pathology In Gulf War Illness By Modulating Bacteriome-Virome Associated Inflammation And Microglia-Neuron Proinflammatory Crosstalk, Punnag Saha, Peter T. Skidmore, Larinda A. Holland, Ayan Mondal, Dipro Bose, Ratanesh K. Seth, Kimberly Sullivan, Patricia A. Janulewicz, Ronnie Horner, Nancy Klimas, Mitzi Nagarkatti, Prakash Nagarkatti, Efrem S. Lim, Saurabh Chatterjee
Faculty Publications
Gulf War Illness (GWI) is a chronic multi-symptomatic illness that is associated with fatigue, pain, cognitive deficits, and gastrointestinal disturbances and presents a significant challenge to treat in clinics. Our previous studies show a role of an altered Gut-Brain axis pathology in disease development and symptom persistence in GWI. The present study utilizes a mouse model of GWI to study the role of a labdane diterpenoid andrographolide (AG) to attenuate the Gut-Brain axis-linked pathology. Results showed that AG treatment in mice (100 mg/kg) via oral gavage restored bacteriome alterations, significantly increased probiotic bacteria , , and , the genera that …
Nanoparticles For Targeted Drug Delivery To Cancer Stem Cells: A Review Of Recent Advances, Yavuz Nuri Ertas, Keyvan Abedi Dorcheh, Ali Akbari, Esmaiel Jabbari
Nanoparticles For Targeted Drug Delivery To Cancer Stem Cells: A Review Of Recent Advances, Yavuz Nuri Ertas, Keyvan Abedi Dorcheh, Ali Akbari, Esmaiel Jabbari
Faculty Publications
Cancer stem cells (CSCs) are a subpopulation of cells that can initiate, self-renew, and sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug resistance in cancer therapy. CSCs reside within a niche maintained by multiple unique factors in the microenvironment. These factors include hypoxia, excessive levels of angiogenesis, a change of mitochondrial activity from aerobic aspiration to aerobic glycolysis, an upregulated expression of CSC biomarkers and stem cell signaling, and an elevated synthesis of the cytochromes P450 family of enzymes responsible for drug clearance. Antibodies and ligands targeting the unique factors that maintain the niche are utilized …
High-Throughput Computation Of New Carbon Allotropes With Diverse Hybridization And Ultrahigh Hardness, Mohammed Al-Fahdi, Alejandro Rodriguez, Tao Ouyang, Ming Hu
High-Throughput Computation Of New Carbon Allotropes With Diverse Hybridization And Ultrahigh Hardness, Mohammed Al-Fahdi, Alejandro Rodriguez, Tao Ouyang, Ming Hu
Faculty Publications
The discovery of new carbon allotropes with different building blocks and crystal symmetries has long been of great interest to broad materials science fields. Herein, we report several hundred new carbon allotropes predicted by the state-of-the-art RG2 code and first-principles calculations. The types of new carbon allotropes that were identified in this work span pure sp2 , hybrid sp2/sp3 , and pure sp3 C–C bonding. All structures were globally optimized at the first-principles level. The thermodynamic stability of some selected carbon allotropes was further validated by computing their phonon dispersions. The predicted carbon allotropes …
Nanoparticles For Targeted Drug Delivery To Cancer Stem Cells: A Review Of Recent Advances, Yavuz Nuri Ertas, Keyvan Abedu Dorcheh, Ali Akbari, Esmaiel Jabbari
Nanoparticles For Targeted Drug Delivery To Cancer Stem Cells: A Review Of Recent Advances, Yavuz Nuri Ertas, Keyvan Abedu Dorcheh, Ali Akbari, Esmaiel Jabbari
Faculty Publications
Cancer stem cells (CSCs) are a subpopulation of cells that can initiate, self-renew, and sustain tumor growth. CSCs are responsible for tumor metastasis, recurrence, and drug resistance in cancer therapy. CSCs reside within a niche maintained by multiple unique factors in the microenvironment. These factors include hypoxia, excessive levels of angiogenesis, a change of mitochondrial activity from aerobic aspiration to aerobic glycolysis, an upregulated expression of CSC biomarkers and stem cell signaling, and an elevated synthesis of the cytochromes P450 family of enzymes responsible for drug clearance. Antibodies and ligands targeting the unique factors that maintain the niche are utilized …
Ahr Expression On Rorc-Expressing Immune Cells Is Essential For I3c-Mediated Protection Against Colitis, Michal C. Williams
Ahr Expression On Rorc-Expressing Immune Cells Is Essential For I3c-Mediated Protection Against Colitis, Michal C. Williams
Senior Theses
Colitis is an inflammatory bowel disorder (IBD) whose etiology is attributed to modification in the luminal microbiota and dysregulation in the immune response. Indole is a signaling molecule which is naturally produced by gut luminal microbiota. Indole-3- carbinol (I3C) is a compound commonly found in vegetables and a ligand for the aryl hydrocarbon receptor (AhR). Previous studies have detected decreased expression and activation on the AhR receptor in colitis patients, thought to possibly alter gut microbiota metabolism, subsequently promoting colitis. 1 AhR, expressed in a variety of immune and epithelial cells, contributes to gut homeostasis by affecting vital mediators such …
Physical Activity Among Adults Residing In 11 Countries During The Covid-19 Pandemic Lockdown, Kele Ding, Jingzhen Yang, Ming-Kai Chin, Lindsay Sullivan, J. Larry Durstine, Verónica Violant-Holz, Giyasettin Demirhan, Nara R.C. Oliveira, Biljana Popeska, Garry Kuan, Waheeda Khan, Jianhui Dai, Xia Xu, Zornitza Mladenova, Govindasamy Balasekaran, Gary A. Smith, Global Community Health-Covid-19 Collaborative Research Team
Physical Activity Among Adults Residing In 11 Countries During The Covid-19 Pandemic Lockdown, Kele Ding, Jingzhen Yang, Ming-Kai Chin, Lindsay Sullivan, J. Larry Durstine, Verónica Violant-Holz, Giyasettin Demirhan, Nara R.C. Oliveira, Biljana Popeska, Garry Kuan, Waheeda Khan, Jianhui Dai, Xia Xu, Zornitza Mladenova, Govindasamy Balasekaran, Gary A. Smith, Global Community Health-Covid-19 Collaborative Research Team
Faculty Publications
During the novel coronavirus (COVID-19) pandemic, physical activity (PA) behaviors were altered worldwide due to public health measures such as “lockdown.” This study described PA among adults residing in 11 countries during COVID-19 lockdown and examined factors associated with PA engagement. We conducted a cross-sectional anonymous survey among adults (≥18 years old) in 11 countries (Brazil, Bulgaria, China, India, Ireland, Malaysia, North Macedonia, Singapore, Spain, Turkey, United States). Of 11,775 participants, 63.7% were female and 52.8% were 18–34 years old. More than 40% of participants were insufficiently active (43.9%) and reported a decrease in their PA during lockdown (44.8%). Statistically …