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Emergence, Differentiation, And Modeling Of Hematopoietic Stem Cells In Developing Embryos, Lucy Shive

Caroliniana Undergraduate Research Journal

In the field of developmental biology, the understanding of embryogenesis is driven by ever-advancing techniques of studying embryos’ structures and behaviors. Yolk sacs are critical to an embryo’s survival and its function in producing a mature organism from a simple zygote. A hallmark of embryonic yolk sacs is their production of primitive hematopoietic stem cells (HSCs). Recent research has explored the mechanisms by which these HSCs develop and migrate, as well as the mechanisms by which they differentiate into various cell types. This more thorough understanding of HSCs is the basis for the development of embryo models, peri-gastruloids, from stem …

Back Matter

Caroliniana Undergraduate Research Journal

This is the Back Matter for Vol. 1, Iss. 1: "The Blueprint" in the Caroliniana Undergraduate Research Journal. The Back Matter includes the following sections:  The Editorial Board, About the Authors, and the Back Cover of the issue. Here you can find more about the contributors that made this issue possible.

Tax Avoidance And Esg Disclosure Mandates: International Evidence, Sadok El Ghoul, Omrane Guedhami, Yongtae Kim, Hyo Jin Yoon

Faculty Publications

This paper examines how regulations mandating environmental, social, and governance (ESG) disclosure affect corporate tax behavior. Using a difference-in-differences analysis on a sample of firms from 48 countries, we find that ESG disclosure mandates lead to significant reductions in tax avoidance, with stronger effects for mandates that include tax-relevant provisions. We identify increases in ESG information transparency and improvements in firms’ ESG performance as channels through which ESG disclosure mandates reduce tax avoidance. We further find that the decrease in tax avoidance following ESG disclosure mandates is more pronounced in countries with weaker financial disclosure requirements, legal and tax enforcement, …

Tunable Shock And Vibration Damping In Metal Laser Powder Bed Fusion Components Via Controlled Post-Print Compaction Of Particle Damper Cavities, Joud N. Stame, Yanzhou Fu, Samuel Roberts, Austin Downey, Tianyu Zhang, Lang Yuan, Daniel Kiracofe

Faculty Publications

Components manufactured by Laser Powder Bed Fusion (LPBF) can incorporate particle dampers (PDS) by retaining unfused powder within internal pockets, providing inherent vibration suppression without added mass or separate damping components. This study investigates the damping performance of such LPBF-integrated PDs through two complementary approaches: (1) quantifying the effect of post-printing volume compression on energy absorption by mechanically indenting the damper pocket, and (2) evaluating how variations in particle packing density influence the dynamic response under both sinusoidal and transient impulse excitation. Experimental results from shaker and shock testing demonstrate that increased packing density, whether by compression or tighter confinement, …

Examining Reporting And Risk-Avoidance Intentions Among Residents Of High-Crime Neighborhoods: Results From A City-Wide Survey Experiment, Paige E. Vaughn, Matt Vogel

Faculty Publications

Objectives

Examine how offense severity and victim–offender relationship shape intentions to report violence and engage in avoidance behaviors among residents of high-crime neighborhoods.

Methods

A 2×2 factorial survey experiment was embedded in a community survey of 220 adults from nine high-crime St. Louis, MO neighborhoods. Logistic regression models estimated vignette effects on reporting and avoidance intentions.

Results

Firearm presence increased intentions to contact police and community workers and avoid risk. Simple assaults by strangers were more likely to be reported to police than those by acquaintances. Respondents expressed willingness to report to police and family or friends, but not community …

Hidden Costs Of Ethical Fashion: Sustainable Development Goals And Garment Worker Exploitation In Bangladesh, Md. Rafiqul Islam Rana M.S., Ph.D.

Faculty Publications

Across garment factories in the Global South, the promise of “ethical fashion” coexists with poverty wages and retaliation. This study examines why the global call for decent work has not improved labor conditions in Bangladesh's ready-made garment industry. Twelve semistructured interviews with production workers were thematically analyzed through Critical Theory and Labor Process Theory. Five persistent problems emerged: wage manipulation, audit and compliance evasion, silencing of worker voice, restrictions on mobility, and the disposal of older workers. A single positive theme, workplace safety and child-labor prevention, showed limited progress. Overall, sustainability rhetoric remains symbolic while buyer cost pressures drive exploitation. …

Hidden Costs Of Ethical Fashion: Sustainable Development Goals And Garment Worker Exploitation In Bangladesh, Md. Rafiqul Islam Rana M.S.,Ph.D

Faculty Publications

Across garment factories in the Global South, the promise of “ethical fashion” coexists with poverty wages and retaliation. This study examines why the global call for decent work has not improved labor conditions in Bangladesh's ready-made garment industry. Twelve semistructured interviews with production workers were thematically analyzed through Critical Theory and Labor Process Theory. Five persistent problems emerged: wage manipulation, audit and compliance evasion, silencing of worker voice, restrictions on mobility, and the disposal of older workers. A single positive theme, workplace safety and child-labor prevention, showed limited progress. Overall, sustainability rhetoric remains symbolic while buyer cost pressures drive exploitation. …

Reproducing Advantage: Inequality In Ncaa Leadership Programming, Jessica K. Brougham, Elizabeth A. Taylor

Journal of Issues in Intercollegiate Athletics

Leadership programming in NCAA Division I athletics is designed to support holistic athlete development, including career readiness, financial literacy, and personal growth. However, participation in selective initiatives like the Student-Athlete Advisory Committee (SAAC) is often limited, raising concerns about equality and access. Through the theory of social reproduction, our study examines how these programs reflet and reinforce structural inequalities. Interviews with athletic staff reveal selection procedures (or lack thereof) privilege athletes who already possess social and cultural capital and therefore reproduce existing hierarchies rather than serve as a developmental tool. The findings highlight the importance of transparent selection criteria, intentional …

Ncaa’S Mental Health Best Practices Still Need Coaching: Perceptions Of Division I Student-Athletes On Strategies And Support Offered By Their Universities, Christopher C. Boyer, Jason Bocarro, Corey Johnson, Austin Thompson-Spain, Lulu Black

Journal of Issues in Intercollegiate Athletics

The NCAA has recognized the growing mental health crisis among student-athletes over the last decade and responded by publishing best practices, passing related legislation, and conducting surveys with student-athletes and coaches regarding mental health. This qualitative study explored the perceptions and insights of 22 Division I student-athletes on current strategies and resources designed to provide the best mental health support to them, along with what they perceive as the barriers or resource deficiencies related to seeking help. This applied research was done in the context of the best practices outlined in the NCAA’s Interassociation Consensus Document: Mental Health Best Practices, …

Game Without A Voice: College Athletes’ Symbolic Participation In Institutional Decisions, Eric G. Kramer, Karina Jolly, Chris Corr, Sarah Stokowski

Journal of Issues in Intercollegiate Athletics

This study examined decision-making by student-athlete advisory committee (SAAC) members within a hegemonic characterization of the National Collegiate Athletic Association (NCAA). Findings revealed that athletes prioritized decisions with tangible, immediate impact – such as mental and physical health and peer support – over broader systemic issues like NCAA legislation. While athletes actively participated in select areas, their perceived influence remained low, particularly within athletic department policy decisions, where findings indicated the greatest gap between participation and desired influence. Such findings reflect a systemic power imbalance that limits athlete agency, reinforced by fears of retribution and structural exclusion from meaningful governance. …

Rock On! Examining The Relationship Between Armed Conflict And Rock Protest Music, Dylan Conner Dunn

Senior Theses

This thesis explores the relationship between rock protest music and wars, armed conflicts, and other related events. The purpose of this research is to explore how such specific events, or war and conflict in general, influence rock songwriters. This paper examines a series of nine rock songs ranging across five decades, from the Vietnam War to the 2010s. A variety of artists wrote and recorded these songs, ranging from hard rock to classic rock, to folk rock and beyond. Some are more audially intense, lyrically visceral, and featuring explicit language, whereas others are much more stripped-back and “family-friendly.” Each of …

Loss Of Sarm1 Affects Myelin Uptake And Clearance In Macrophages, Grace J. Bergeron

Senior Theses

Clearance of myelin debris is an essential step in nerve regeneration after injury in both the central nervous system (CNS) and peripheral nervous system (PNS), a process that is primarily carried out by macrophages. Failure to phagocytose and clear myelin can prolong inflammation and impair recovery. Sterile alpha and TIR motif-containing protein 1 (SARM1) is well researched as a regulator of axonal degeneration, yet its role in macrophages is still unclear. This study investigates how sarm1 deletion and cytokine signaling influence macrophage uptake and clearance of CNS and PNS myelin in vitro. Splenic macrophages isolated from wild-type (WT) and sarm1 …

A Guide To Environmentally Sustainable Filmmaking In South Carolina, Christina Vera Dobrowolski

Senior Theses

The entertainment industry has a massive environmental impact. This information is not new in the filmmaking world, as multiple mainstream efforts exist to curb the material-intensive production of live action films and TV. One of these efforts is the use of voluntary sustainable guidelines, which serve as tools that outline sustainable best practices and resources that can help achieve them. However, current guidelines often lack practicality— focusing more on altruism rather than core economic factors that ultimately drive filmmaking. This project aims to address that gap for filmmakers in South Carolina by offering a website featuring attainable, state-specific resources for …

We're All Ramblers, Here: American National Identity As Articulated Through The Sounds And Stories Of Bluegrass Music, Greyson M. Sherman

Senior Theses

This creative thesis argues that bluegrass music, through its multicultural origins and its central "Rambler" archetype, articulates a distinctly American negotiation between freedom and rootedness — one that extends far beyond the genre's narrow popular image. Drawing on musicological scholarship and cultural history, the paper first recovers bluegrass's suppressed origins in the convergence of West African, Anglo- Celtic, and broader European traditions, complicating narratives that position the genre as exclusively white and Appalachian. It then introduces the Rambler — the restless, longing figure who haunts bluegrass lyrically and structurally — as both a product of that history and a metaphorical …

Heterogeneity Of Treatment Effects In Transcranial Direct Current Stimulation For Knee Osteoarthritis Pain And Symptoms, Chiyoung Lee, Xiaoxiao Sun, Juyoung Park, Chen X. Chen, Christine Pellegrini Ph.D., Nan-Kuei Chen, David O. Garcia, Heewon Kim, C. Kent Kwoh, Hyochol Ahn

Faculty Publications

Introduction: Although heterogeneity of treatment effects (HTEs) is commonly observed in clinical trials, it has received little attention in studies on transcranial direct current stimulation (tDCS).

Objectives: This study identified the presence of HTE in tDCS treatment among participants with symptomatic knee osteoarthritis (KOA) and explored participant characteristics associated with this heterogeneity.

Methods: This secondary analysis of a randomized clinical trial included 120 participants with symptomatic KOA who received 15 daily sessions of home-based 2-mA active or sham tDCS over 3 weeks. We used a multitrajectory analysis to identify distinct subgroups based on the longitudinal trajectories of KOA pain and …

Heterogeneity Of Treatment Effects In Transcranial Direct Current Stimulation For Knee Osteoarthritis Pain And Symptoms, Chiyoung Lee, Xiaoxiao Sun, Juyoung Park, Chen X. Chen, Christine Pellegrini, Nan-Kuei Chen, David O. Garcia, Haewon Kim, C. Kent Kwoh, Hyochoi Ahn

Faculty Publications

Introduction: Although heterogeneity of treatment effects (HTEs) is commonly observed in clinical trials, it has received little attention in studies on transcranial direct current stimulation (tDCS).

Objectives: This study identified the presence of HTE in tDCS treatment among participants with symptomatic knee osteoarthritis (KOA) and explored participant characteristics associated with this heterogeneity.

Methods: This secondary analysis of a randomized clinical trial included 120 participants with symptomatic KOA who received 15 daily sessions of home-based 2-mA active or sham tDCS over 3 weeks. We used a multitrajectory analysis to identify distinct subgroups based on the longitudinal trajectories of KOA pain and …

The Influence Of Mentoring On Educational Attitudes, Beliefs, And Behaviors (Eabbs): A Scoping Review, Amanda L. Davis, Jennifer Koide, Savannah B. Simpson, Samuel Mcquillin, Michael D. Lyons

Faculty Publications

Youth mentoring is a popular means for preventing negative psychosocial outcomes (e.g., high-risk behaviors, school dropout) and promoting positive ones (e.g., matriculation, goal setting). Mentors matched with youth through formal programs, such as Big Brothers Big Sisters, are uniquely positioned to promote the development of the mentee’s positive educational attitudes, beliefs, and behaviors (EABBs; e.g., academic engagement, grit, growth mindset). While school staff, such as school psychologists, are often unable to directly serve all students in need of support due to lack of time or large caseloads, youth mentoring may be a means to target EABB development. However, a critical …

Vaccination Coverage And Factors Associated With Covid-19 Vaccination In The Adult African American Community In South Carolina: A Cross-Sectional Survey, Brittany Divon Smith

Theses and Dissertations

The COVID-19 pandemic has disproportionately affected African American communities, revealing longstanding disparities in healthcare access and outcomes. In South Carolina, where these inequities are particularly evident, understanding the determinants of COVID-19 vaccine uptake among African Americans is crucial for advancing health equity. This thesis examines vaccination coverage and explores social, economic, and psychological predictors of vaccine uptake in a sample of 305 African American adults through a cross-sectional survey conducted in 2023.

Vaccination status was categorized as unvaccinated, partially vaccinated, and fully vaccinated (with or without a booster). Ordinal logistic regression analyses were performed to examine associations between vaccination status …

Ready-To-Teach Reads: Standards-Aligned Novel Studies For Seventh Grade Using Contemporary Middle Grade Fiction, Elizabeth Duvall

Senior Theses

This project aims to provide middle school English teachers with an easy way to update their curriculum to be culturally relevant using ready-to-teach unit plans based on diverse novels. Since research shows students benefit from reading texts from diverse cultures, each novel features minority voices. Both units include lesson plans for each day, and resources like slideshows, worksheets, and discussion questions. They were created using the South Carolina College and Career Ready Standards for English Language Arts. While these units are tailored to South Carolina teachers, they can be used by any educator whose standards align with the units’ learning …

Searching For Temporal Variations In The Fine-Structure Constant Using Espresso Spectrograph Data, David Hoffman Iv

Senior Theses

The fine-structure constant α is a dimensionless constant, defined as e²/(4πε₀ℏc) ≈ 1/137. On the order of human timescales, its value is very much unchanging, however, in recent years there has been extensive debate over whether or not the value of α has remained constant over cosmological timescales. With the natural corollary to a changing α being that either one or multiple of its constituent physical constants have also changed in value, observing a variation in the fine-structure constant would have vast ramifications for our understanding of the nature of the early universe and how it has evolved. While past …

"Ever Changing, Simply Amazing:" A Storymap Of Adaptive Reuse At Brookgreen Gardens, Lola G. Bellah

Senior Theses

In 1930, Archer Huntington, a scholar of Hispanic studies, used a portion of the fortune he inherited from the Central Pacific Railroad to purchase The Oaks, Brookgreen, Springfield, and Laurel Hill plantations in coastal South Carolina and build Atalaya Castle, a winter home on the Atlantic. His wife Anna Hyatt Huntington, a sculptor, led the effort to turn the 19,000 acres into America’s first public sculpture garden, known since as Brookgreen Gardens. In the construction process, some structures from Brookgreen Plantation were repurposed while others were removed from the landscape.

Though Brookgreen Gardens has since interpreted its plantation history through …

Curating Attendee-Centered Corporate Event Experiences Through The Strategic Implementation Of Psychological Principles, Alexis G. Mullendore

Senior Theses

This thesis explores how psychological principles can inform event professionals’

decisions in the planning and execution of attendee-centered corporate events. In the modern

experience economy, corporations increasingly prioritize engaging, high-production events for

employees and stakeholders, while attendee expectations for immersive, spectacle experiences

continue to rise. Therefore, the importance of designing corporate events that balance clients’

fiscal and objective needs with attendees’ experience-driven expectations has become

increasingly recognized. This shift toward a human-focused approach prompted the researcher to

examine how psychological principles can inform the design and execution of events. The

project was conducted through a three-phase research process consisting of …

Beyond The Individual: Exploring Structural Explanations Of Homelessness Through Thematic Analysis Of Extant Research, Madison R. Mcclain

Senior Theses

This thesis examines how homelessness is defined, explained, and addressed within contemporary U.S. research using Critical Race Theory (CRT) and Intersectionality as guiding frameworks. Through a qualitative, deductive thematic analysis of 16 peer-reviewed articles, this study identifies six key themes related to structural causation, policy governance, measurement practices, racial inequality, dominant narratives, and intersecting systems of disadvantage. Findings reveal that while structural explanations of homelessness are widely acknowledged, they are inconsistently defined and often insufficiently theorized. Institutional systems primarily function to manage rather than resolve homelessness, while measurement practices and definitions actively shape who is recognized and prioritized. Additionally, structural …

Modernity And Transcendence: Gendered Subjectivity In Miss Lonelyhearts And A Spy In The House Of Love, Rachel Loging

Senior Theses

This thesis examines how Nathanael West’s Miss Lonelyhearts (1933) and Anaïs Nin’s A Spy in the House of Love (1954) represent gendered subjectivity under the conditions of modernity. Drawing on Ben Singer’s account of modern experience and Rita Felski’s analysis of modernity as a masculine structure organized around autonomy and production, it argues that both texts stage encounters between masculinity and femininity as sites of interpretive conflict. In Miss Lonelyhearts, masculinity remains tied to coherence, authority, and the paradigm of Christ, and repeatedly attempts to impose order through perception, relationships, and religion. These efforts ultimately collapse, exposing the futility and …

Effect Of Ginseng On Obesity And Neurogenesis, Hayden L. Withers, Claudia A. Grillo, Lawrence P. Reagan, Natalia Maciejewska, Sai V. Nallu, Jennifer L. Woodruff

Senior Theses

Obesity and major depressive disorder are two conditions with high comorbidity as well as overlapping pathophysiological mechanisms, including neuroinflammation, metabolic/endocrine dysfunction, and impaired hippocampal neurogenesis. Panax ginseng, a medicinal herb, is known to demonstrate anti-inflammatory and metabolic regulatory properties. Ginseng has demonstrated its effective antidepressant-like effects within preclinical studies, but its potential to restore neurogenesis in the context of obesity-induced depression is not clear. Within this study, male Sprague-Dawley rats were tested in either a high fat diet (HFD) or control diet (Cont) for 12 weeks and then was treated subsequently with daily intraperitoneal injections of either ginseng or saline …

Breaking The Cycle: Implementing Journal-Based Emotional Regulation Workshops At South Carolina’S Department Of Juvenile Justice, Sarah Hobson

Senior Theses

Incarcerated youth experience disproportionately high rates of trauma exposure, estimated at 70% to 90%, which significantly impacts emotional regulation and behavior, keeping them in a cycle of repeated offense and increased recidivism rates (Branson et al., 2017). Despite the prevalence of these psychological needs, juvenile justice systems often lack consistent, trauma-informed programming that addresses the underlying causes of delinquent behavior. This study examines the implementation and impact of a structured, eight-week trauma-informed journaling intervention conducted as a pilot program within the South Carolina Department of Juvenile Justice. This program was implemented among a small cohort of participants at the Juvenile …

Physical And Behavioral Health Diagnoses And Comorbidities Associated With Transition From Military Health System To Veterans Health Care Among Post-­ 9/11 Veterans, Nikki R. Wooten, Megan E. Amaun, Madeline Meyers, Prince Nii Ossah Addo, Jeffery Bowers, Felicia R. Carey, Rudolph P. Rull, Edward J. Boyko, Nathaniel Bell, Ana Defede-Lopéz, Mary Jo V. Pugh

Faculty and Staff Publications

Objective

To identify factors associated with transitioning from Military Health System (MHS) to Veterans Health Administration (VHA) care in post-9/11 veterans.

Study Setting and Design

Retrospective cohort study from the Long-Term Impact of Military-Relevant Brain Injury Consortium Phenotype Study.

Data Sources and Analytic Sample

Population-level data were analyzed from MHS and VHA electronic health data (FY2000-2020). Participants received ≥ 3 years of MHS care and separated from the military before October 1, 2016. The primary outcome was transition from MHS to VHA care after military separation. Covariates included demographic, military, and deployment characteristics at military separation; physical, mental, and substance …

Physical And Behavioral Health Diagnoses And Comorbidities Associated With Transition From Military Health System To Veterans Health Care Among Post-9/11 Veterans, Nikki R. Wooten, Megan E. Amaun, Madeleine Myers, Price N.O. Addo, Jeffrey Bowers, Felicia R. Carey, Rudolph P. Rull, Edward J. Boyko, Nathaniel Bell Ph.D., Ana Defede-Lopéz, Mary Jo V. Pugh

Publications

Objective

To identify factors associated with transitioning from Military Health System (MHS) to Veterans Health Administration (VHA) care in post-9/11 veterans.

Study Setting and Design

Retrospective cohort study from the Long-Term Impact of Military-Relevant Brain Injury Consortium Phenotype Study.

Data Sources and Analytic Sample

Population-level data were analyzed from MHS and VHA electronic health data (FY2000-2020). Participants received ≥ 3 years of MHS care and separated from the military before October 1, 2016. The primary outcome was transition from MHS to VHA care after military separation. Covariates included demographic, military, and deployment characteristics at military separation; physical, mental, and substance …

Is Access Enough?: Toward A Blueprint For Prosocial Digital Interventions In Schools (A Case Study On The Implementation Of A Cmc-Based Gratitude Intervention), Carmen Latrice Landy

Theses and Dissertations

This organizational autoethnography examines the process by which a researcher-practitioner began implementing a CMC-based gratitude intervention for adolescents in a school setting. Too often, innovations are unable to reach full adoption within organizations because the real-world implications have not been fully considered. This study seeks to bring a deeper understanding of the facilitators of and barriers to school-based implementation. Through observations and critical reflection, this study highlights the importance of relationships, processes, and mutual agreements in any effort to introduce new practices to an organization. Weick’s (1988) findings on sensemaking combined with the constructs of the Consolidated Framework for Implementation …

An Autoethnography Of Organic Representation In Queer Arts Documentation, Eden Joyce Prime

Theses and Dissertations

The goal of this project is to illustrate the importance of documentation processes grounded in ‘organic representation,’ a media practice paradigm from the work of A. J. Christian (2020). Organic representation prioritizes narrative co-creation, informed consent, and intersections of identity and cultural knowledge. To effectively document a subject’s lived experience, a media professional must share intersections of identity and/or culture with the subject and provide opportunities for narrative co-creation. Intersectional positionality gives media practitioners authority to document important narratives in a way that honors the identity and contextual significance of the subject. For journalists documenting the life and work of …