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Evaluating The Impact Of Rapid Response Electroencephalogram In Post-Cardiac Arrest Patients, Lauren Lee Steffen

Doctor of Nursing Practice Scholarly Projects

Problem Statement: Timely diagnosis and treatment of nonconvulsive seizures (NCS) and nonconvulsive status epilepticus (NCSE) are critical for improving patient outcomes after a cardiac arrest. However, NCSE can only be confirmed with an electroencephalogram (EEG), which is either considerably delayed or unavailable in the Emergency Department and Intensive Care Unit (ICU). Purpose: This project aimed to describe the impact of a rapid response electroencephalogram (rrEEG) brain monitor on improving time- to- acquisition and length of stay in the Intensive Care Unit for post-resuscitated cardiac arrest survivors; additionally, does rrEEG increase nurse's knowledge and confidence in managing complex seizure patterns? Method(s): …

Spectre Of Justice: Russian Reform In The Courtrooms Of Dostoevsky And Tolstoy, Abby Moore

Senior Theses

The Great Reforms of Alexander II are regarded as transformative policies in the history of Tsarist Russia, drastically changing the empire’s social and political fabric. The judicial reforms of 1864 in particular addressed longstanding issues within the existing criminal justice system, yet they also liberalized the institution at large. Following in the West’s footsteps, the reforms introduced an unprecedented level of democracy into Russia’s courtroom. Among the critics of these changes were renowned authors Fyodor Dostoevsky and Leo Tolstoy, both of whom used the realm of fiction to explore their respective concerns with reformed Russian jurisprudence. Both authors bring distinct …

Motivations Behind The Rise And Success Of Homeopathy In India, Kavya Patchipulusu

Senior Theses

Homeopathy is a form of medicine that is incredibly controversial and is often labeled as a fraudulent, placebo effect drug, that can have potentially dangerous side effects. This is the picture that is painted of homeopathy in the United States and many other countries in which these medicines are banned in distribution or highly unregulated. In contrast, India has popularized and well-integrated homeopathy into their medical systems with government backing and consistent funding towards accredited homeopathic institutions and funding hospital systems. This paper will explore the circumstances and health care dynamics of India that allowed homeopathy to gain the level …

Analyzing Colonial South Carolina's Trade Landscape Through The Ricardian Model, Dylan M. Peddemors

Senior Theses

The state of South Carolina existed as a British colony from its founding in 1663 until it declared independence in 1776. During this period, South Carolina operated as a plantation-based, cash-crop economy relying on two primary exports: rice and indigo. The colony displayed nearly complete specialization in its exports of these crops while importing different goods. The theory of comparative advantage in trade relationships crafted by British economist David Ricardo in the 18th century concludes that gains from trade emerge when trade partners specialize in the production and exportation of the goods of which they have the lowest opportunity cost. …

Preserving Viewpoint Pluralism And Democratic Principles: Florida's "Divisive Concepts" Law And Strategies For Challenging The Law's Enforcement In K-12 And Higher Education, Abigail Dallmann

The Journal of Law and Education

No abstract provided.

The Arabic Influence On The Spanish Language: Sociocultural Mechanisms Of Language Change Under Islamic Rule In The Iberian Peninsula, Reagan Borland

Senior Theses

After Latin, which makes up about 75-80% of the Spanish lexicon (Comparán Rizo, 2006, p. 17), Arabic is the most important linguistic contributor to the branch of Romance languages that would come to be known as Spanish or Castellano (Castilian), surpassing Germanic influence and that of other contributors such as French and Celtic languages. The broad range of Arabisms found in Spanish can be attributed to certain cultural and social changes that took place under Arab-Muslim rule in the Iberian Peninsula between 711 and 1492 and during the period following the so-called “Reconquista” of Spain by the Christian kingdoms to …

The Impact Of Individual Culture On Purchase Decisions Of Fast Fashion In Brazil, Lucie S. Speck

Senior Theses

Fast fashion is an emerging method of production in the apparel industry that is characterized by lower-quality materials and faster production timelines than the traditional methods of producing clothing. It is becoming a trending topic in modern business due to its negative social and environmental impact, as brands that use fast fashion production processes are constantly being criticized for inhumane labor practices and large amounts of textile waste.

This research proposes two models using a survey as its main research method. The first model determines how financial situation, collectivism as a cultural value, and education level impact whether social media …

Plath Fostered It, Women Are Nurturing It: Cycles Of Existential And Confessional Women's Writing In The Mid-20th Century And Beyond, Sophie Elisabeth Conrad

Senior Theses

During the mid-20th century, a wide-ranging yet topically focused genre of women’s writing began to emerge in earnest, currently categorized as existential and confessional. Works like Simone de Beauvoir’s The Second Sex (1949) and Betty Friedan’s The Feminine Mystique (1963) offer explanations of why an ineffable feeling of malaise permeated the lives of 20th-century women and led them to adopt these methods of writing and thinking. However, existential feelings akin to that of the 20th-century female malaise have returned to stake their claim on the minds of 21st-century women, evidenced in popular contemporary works such as Otessa Moshfegh’s My Year …

A Covenant People: Providentialism In Seventeenth-Century New England And Its Impact On The Development Of The Salem Witch Trials, Gracie L. Vess

Senior Theses

This project explores the New English Puritan ideology of providentialism from the first settlement of New England in 1620 to the Salem Village witch trials in 1692. During this period New England watched its motherland experience civil war, the overthrow of the monarchy, the installation of a commonwealth, the failure of the Puritan Reformation, the restoration of the monarchy, and the Glorious Revolution. These events influenced the way New Englanders saw England’s relationship with God as well as the meaning behind their providential purpose by allowing them to believe God had turned his wrath on England, so the colonists needed …

Prenatal And Postnatal Disparities In Very-Preterm Infants In A Study Of Infections Between 2018–2023 In Southeastern Us, Robin B. Dail Phd, Rn, Faan, Kayla C. Everhart Phd, Rn, Victor N. Iskersky, Weili Chang, Kimberley Fisher, Karen Warren Phd, Rn, Heidi J. Steflik, James W. Hardin Ph.D.

Publications

Background: The birthrate of Black preterm (BPT) infants is 65% higher than White preterm (WPT) infants with a BPT mortality that is 2.3 times higher. The incidence of culture-positive late-onset sepsis is as high as 41% in very-preterm infants. The main purpose of this study was to examine thermal gradients and the heart rate in relation to the onset of infection. This report presents disparities in very-preterm infection incidence, bacteria, and mortality data amongst BPT and WPT infants. Methods: 367 preterms born at < 32 weeks gestational age (GA) between 2019–2023 in five neonatal intensive care units (NICUs) were enrolled to study the onset of infections and dispositions; REDCap data were analyzed for descriptive statistics. Results: The 362 infants for analyses included 227 BPTs (63.7%) and 107 WPTs (29.6%), with 28 infants of other races/ethnicities (Hispanic, Asian, and other), 50.6% female, mean GA of 27.66 weeks, and 985.24 g birthweight. BPT infants averaged 968.56 g at birth (SD 257.50), and 27.68 (SD 2.07) weeks GA, compared to WPT infants with a mean birthweight of 1006.25 g (SD 257.77, p = 0.2313) and 27.67 (SD 2.00, p = 0.982) weeks GA. Of the 426 episodes of suspected infections evaluated across all the enrolled infants, the incidence of early-onset sepsis (EOS) was 1.9%, with BPT infants having 2.50 times higher odds of EOS than WPT infants (p = 0.4130, OR (odds ratio) = 2.50, p_or = 0.408). The overall incidence of late-onset sepsis (LOS) was 10.8%, with LOS in 11.9% of BPT infants versus 9.3% (p = 0.489, OR = 1.21, p_or = 0.637) of WPT infants. BPT infants made up 69.2% of the 39 infants with Gram-positive infections vs. 25.6% for WPT infants; 16 infants had Gram-negative culture-positive infections, with 81.2% being BPT infants versus 18.8% being WPT infants. Of the 27 urinary tract infections, 78% were in BPTs. The necrotizing enterocolitis incidence was 6.9%; the incidence in BPT infants was 7.5% vs. 6.5% in WPT infants. The overall mortality was 8.3%, with BPTs at 8.4% vs. WPT infants at 9.3%, (p = 0.6715). Conclusions: BPTs had a higher rate of positive cultures, double the Gram-negative infections, a much higher rate of urinary tract infections, and a higher rate of mortality than their WPT counterparts. This study emphasizes the higher risk of morbidity and mortality for BPTs.

Creation Of Bound Half-Fermion Pairs By Solitons, Sapan Karki, Brett Altschul

Faculty Publications

In the presence of topologically nontrivial bosonic field configurations, the fermion number operator may take on fractional eigenvalues, because of the existence of zero-energy fermion modes. The simplest examples of this occur in 1+1 dimensions, with zero modes attached to kink-type solitons. In the presence of a kink-antikink pair, the two associated zero modes bifurcate into positive and negative energy levels with energies ±ge^-gΔ, in terms of the Yukawa coupling g≪1 and the distance Δ between the kink and antikink centers. When the kink and antikink are moving, it seems that there could be Landau–Zener-like transitions between these …

The Study Of Biomass Based Polymers And Cyclic Polymers, Yishayah Bension

Theses and Dissertations

Plastics have become an integral part of everyday life, from household care to aerospace applications, polymers are involved in every industry. Most of these polymeric materials are derived from petroleum feedstocks which have deleterious effects on our environment. The production of petrochemicals has led to an increase in greenhouse gases and microplastic pollution which have accelerated climate change. My research focuses on utilizing existing biomasses to improve the plastic economy’s circularity. This work develops new materials from bio-based polymers such as lignin and soybean oil. Raw lignin suffers from inherently weak mechanical properties, poor solubility, processability, and molecular structure ambiguity. …

Association Between Direct Access Laws And Physical Therapy Use And The Effect Of Change In Physical Therapy Use On Subsequent Healthcare Spending, Utilization, And Opioid Use, Dakshu Jindal

Theses and Dissertations

Background

Physical therapy (PT) has been recommended as the first-line treatment for patients with incident musculoskeletal conditions without severe trauma. Initial or early use of PT may help address some of the nation’s most pressing health policy challenges, including escalating healthcare spending and an ongoing opioid epidemic, by encouraging the use of physical therapy as a substitute for expensive surgeries and the use of opioids. Yet, state scope of practice laws have historically restricted the diagnosis and treatment of medical conditions to physicians. Traditionally, patients seeking care from a physical therapist had to obtain a referral from a physician first. …

A Scoping Review On Racial Disparities In South Carolina’S Opioid Epidemic, Jake D'Alto

Senior Theses

This thesis examines racial disparities in opioid-related outcomes within South Carolina, highlighting the disproportionate impact of the opioid epidemic on minority communities. Using a comprehensive literature review methodology, the study analyzes the intersection of race, socioeconomic status, and systemic factors that contribute to heightened risks of opioid misuse and overdose among African American populations. The paper identifies key factors such as poverty, incarceration rates, and limited access to healthcare that exacerbate the opioid crisis in these communities. Additionally, it evaluates the effectiveness of current public health responses and legislative measures in addressing these disparities. The research proposes several actionable interventions, …

"Fueling For A Healthy Life:" A Cooking Class For Adolescent And Young Adult Childhood Cancer Survivors, Hope Dominique

Senior Theses

Following cancer treatment, childhood cancer survivors (CCS) are at an increased risk of developing chronic diseases and face an increased risk of health-related death during adulthood. Recent literature demonstrates that modifying lifestyle factors such as nutrition can reduce the risk of late mortality in survivors, suggesting that interventions promoting a healthy lifestyle may improve quality and quantity of life for CCS. However, many adolescent and young adult (AYA) CCS do not adhere to national dietary guidelines and face both real and perceived barriers to adopting healthier eating habits while in a critical period for establishing behaviors that contribute to lifelong …

Facing Two Fronts: Asian Americans Grappling With Covid-19 And Xenophobic Tensions, Matthew Soos

Senior Theses

This thesis examines the impact of COVID-19-induced discrimination against Asian Americans (AsAms) and its effects on the mental health of college-aged individuals within this demographic. The study specifically targets East and Southeast Asians due to their heightened connection with the pandemic. Data was gathered via a survey disseminated among undergraduate AsAm students at the University of South Carolina. The survey sought information on the occurrence and forms of discrimination encountered pre-pandemic and during the pandemic, alongside the mental health condition and coping mechanisms of the respondents. Moreover, participants were prompted to assess the efficacy of suggested approaches in addressing discrimination. …

Co-Occurrence Of Mental Illness And Substance Use Among Us Pregnant Individuals, 2012-2021, Zhong Li, Curisa M. Tucker Phd, Rn, Cassie L. Odahowski Phd, Mph, Kacey Y. Eichelberger, Jiajia Zhang Ph.D., Peiyin Hung Ph.D

Publications

Aim: Substance use disorders are increasingly prevalent among pregnant individuals, with evident risks of adverse perinatal outcomes. This study examines substance use (tobacco, alcohol and marijuana) among pregnant individuals with mental illness. Methods: A national representative sample of pregnant individuals were derived from 2012 to 2021 National Survey of Drug Use and Health data. Associations of past-year mental illness with past-month polysubstance use and each substance use were analyzed by logistic regression models, with complex sampling weights and survey year. Results: Among 6801 pregnant individuals, 16.4% reported having any mental illness (AMI) in 2012 and 2013, increasing to 23.8% in …

Impacts Of Ride-Hailing On Energy And The Environment: A Systematic Review, Tamara L. Sheldon, Rubal Dua

Faculty Publications

Ride-hailing has expanded substantially around the globe over the last decade and is likely to be an integral part of future transportation systems. We perform a systematic review of the literature on energy and environmental impacts of ride-hailing. In general, empirical papers find that ride-hailing has increased congestion, vehicle miles traveled, and emissions. However, theoretical papers overwhelmingly point to the potential for energy and emissions reductions in a future with increased electrification and pooling. Future research addressing the gap between observed and predicted impacts is warranted.

New Genera And Species Of Caulobacter And Brevundimonas Bacteriophages Provide Insights Into Phage Genome Evolution, Bert Ely, Michael Hils, Aaron Clarke, Maegan Albert, Nadia Holness, Jacob Lenski, Tannaz Mohammadi

Faculty Publications

Previous studies have identified diverse bacteriophages that infect Caulobacter vibrioides strain CB15 ranging from small RNA phages to four genera of jumbo phages. In this study, we focus on 20 bacteriophages whose genomes range from 40 to 60 kb in length. Genome comparisons indicated that these diverse phages represent six Caulobacter phage genera and one additional genus that includes both Caulobacter and Brevundimonas phages. Within species, comparisons revealed that both single base changes and inserted or deleted genetic material cause the genomes of closely related phages to diverge. Among genera, the basic gene order and the orientation of key genes …

Covid-19 Vaccine Effectiveness Among People Living With And Without Hiv In South Carolina, Usa: Protocol Of A Population-Based Cohort Study, Xueying Yang, Jiajia Zhang Ph.D., Bankole Olatosi, Sharon Weissman, Xiaoming Li Ph.D.

Faculty Publications

Introduction Despite the effectiveness of COVID-19 vaccines in preventing severe COVID-19 outcomes, a small percentage of fully vaccinated persons will develop symptomatic or asymptomatic infections with SARSCoV-2, which is referred to as ‘breakthrough COVID-19’. People living with HIV (PLWH) appear to have an elevated risk of severe COVID-19 outcomes, yet the effectiveness of the COVID-19 vaccine in this population remains unclear due to the limited research efforts in this population in the real world. This study aims to characterise and compare the breakthrough COVID-19 (eg, prevalence and disease severity) between PLWH and non-PLWH and then examine whether HIV markers play …

Garnet & Black Spring 2024, University Of South Carolina, Office Of Student Media

Garnet & Black Magazine

No abstract provided.

Neonatal Autonomic Regulation As A Predictor Of Autism Symptoms In Very Preterm Infants, Jessica Bradshaw, Christian O'Reilly, Kayla C. Everhart Phd, Rn, Elizabeth Dixon, Amy Vinyard, Abbas Tavakoli Drph, Robin Dail Phd, Rn, Faan

Publications

No abstract provided.

Neonatal Autonomic Regulation As A Predictor Of Autism Spectrum Disorder In Very Preterm Infants, Jessica Bradshaw, Christian O'Reilly, Kayla C. Everhart, Elizabeth Dixon, Amy Vinyard, Abbas Tavakoli Drph, Robin B. Dail

Publications

Infants born preterm are at a significantly higher likelihood of having autism spectrum disorder (ASD), with reports of a 10-fold increase in the rate of ASD for very preterm infants (VPT, born <32 weeks gestation) [1] and a 20-fold increase for extremely preterm infants (born <28 weeks gestation) [2]. Yet, the etiological link between preterm birth and ASD remains unknown. Preterm birth and ASD are both associated with neurological differences, notably autonomic nervous system (ANS) dysfunction. ANS dysfunction can be measured using abnormal heart rate characteristics (HRCs) and thermal gradients (TGs), and previous research has linked ANS dysfunction to neurodevelopmental impairment and autism-specific outcomes. …

Comparison Of Raw Accelerometry Data From Actigraph, Apple Watch, Garmin, And Fitbit Using A Mechanical Shaker Table, James W. White Iii, Olivia L. Finnegan, Nick Tindall, Srihari Nelakuditi, David E. Brown Iii, Russell R. Pate Ph.D., Gregory J. Welk, Massimiliano De Zambotti, Rahul Ghosal, Yuan Wang, Sarah Burkart, Elizabeth L. Adams, Mvs Chandrashekhar, Bridget Armstrong, Michael W. Beets, Robert Weaver Med, Phd

Faculty Publications

The purpose of this study was to evaluate the reliability and validity of the raw accelerometry output from research-grade and consumer wearable devices compared to accelerations produced by a mechanical shaker table. Raw accelerometry data from a total of 40 devices (i.e., n = 10 ActiGraph wGT3X-BT, n = 10 Apple Watch Series 7, n = 10 Garmin Vivoactive 4S, and n = 10 Fitbit Sense) were compared to reference accelerations produced by an orbital shaker table at speeds ranging from 0.6 Hz (4.4 milligravity-mg) to 3.2 Hz (124.7mg). Two-way random effects absolute intraclass correlation coefficients (ICC) tested inter-device reliability. …

Now It’S Your Turn!: Eye Blink Rate In A Jenga Task Modulated By Interaction Of Task Wait Times, Effortful Control, And Internalizing Behaviors, Kelley E. Gunther

Faculty Publications

Dopamine is a versatile neurotransmitter with implications in many domains, including anxiety and effortful control. Where high levels of effortful control are often regarded as adaptive, other work suggests that high levels of effortful control may be a risk factor for anxiety. Dopamine signaling may be key in understanding these relations. Eye blink rate is a non-invasive proxy metric of midbrain dopamine activity. However, much work with eye blink rate has been constrained to screen-based tasks which lack in ecological validity. We tested whether changes in eye blink rate during a naturalistic effortful control task differ as a function of …

Predicting The Rate Of Degradation Related To Oxygen Electrode Delamination In Solid Oxide-Ion Electrolyzers, Yeting Wen, Kevin Huang

Faculty Publications

Language comprehension is often affected in individuals with post-stroke aphasia. However, deficits in auditory comprehension are not fully correlated with deficits in reading comprehension and the mechanisms underlying this dissociation remain unclear. This distinction is important for understanding language mechanisms, predicting long-term impairments and future development of treatment interventions. Using comprehensive auditory and reading measures from a large cohort of individuals with aphasia, we evaluated the relationship between aphasia type and reading comprehension impairments, the relationship between auditory versus reading comprehension deficits and the crucial neuroanatomy supporting the dissociation between post-stroke reading and auditory deficits. Scores from the Western Aphasia …

Dissociating Reading And Auditory Comprehension In Persons With Aphasia, Rachel M. Harrington, Sigfus Kristinsson, Janina Wilmskoetter, Natalie Busby, Dirk Den Ouden, Chris Rorden, Julius Fridriksson Ph.D., Leonardo Bonilha

Faculty Publications

Language comprehension is often affected in individuals with post-stroke aphasia. However, deficits in auditory comprehension are not fully correlated with deficits in reading comprehension and the mechanisms underlying this dissociation remain unclear. This distinction is important for understanding language mechanisms, predicting long-term impairments and future development of treatment interventions. Using comprehensive auditory and reading measures from a large cohort of individuals with aphasia, we evaluated the relationship between aphasia type and reading comprehension impairments, the relationship between auditory versus reading comprehension deficits and the crucial neuroanatomy supporting the dissociation between post-stroke reading and auditory deficits. Scores from the Western Aphasia …

Health Provider Experiences In Supporting Social Connectedness Between Families And Older Adults Living In Long-Term Care Homes, Anna Garnett, Hannah Pollock, Kristin Prentice, Natalie Floriancic, Lorie Donelle Phd, Rn, Fcan, Carri Hand, Abe Oudshoorn, Yolanda Babenko-Mould, Cheryl Forchuk

Publications

INTRODUCTION: Many people, often older adults, living in long-term care homes (OA-LTCH) became socially isolated during the COVID-19 pandemic due to variable restrictions on in-person visits and challenges associated with using technology for social connectivity. Health providers were key to supporting these OA by providing additional care and facilitating their connections with family using technology such as smartphones and iPads. It is important to learn from these experiences to move forwards from the COVID-19 pandemic with evidence-informed strategies that will better position health providers to foster social engagement for OA-LTCH across a range of contextual situations. OBJECTIVE: This exploratory qualitative …

Investigating Consumer Purchase Intention Of Athleisure Products: A Study Of Lululemon’S Sns Ad, Julia Prigl, Jiyeon Kim Ph.D., Karen Edwards J.D.

Faculty Publications

This study investigated how SNS advertising by Lululemon affected consumer purchase intention from the brand. The influence of specific ad traits such as informativeness, creativity, and emotional appeal, on attitude towards the advertisement, the influence of attitude towards the advertisement on willingness to engage with the brand and the influence of willingness to engage with the brand on purchase intention. A moderating effect of a sedentary or active lifestyle is tested. Also, the influence of perceived behavior of others on subjective norm, and the influence of subjective norm on willingness to engage with the brand were investigated. This study contributes …

The Prevalence Of Gram-Negative Bacteria With Difficult-To-Treat Resistance And Utilization Of Novel Β-Lactam Antibiotics In The Southeastern United States, Y. Vivian Tsai, P. Brandon Bookstaver Pharm.D., Joseph Kohn, Julie Ann Justo, Darrell Childress, Stefanie Stramel, Douglas Slain, Patrick Tu, Mary Joyce B. Wingler, Bruce M. Jones, Daniel T. Anderson, Megan M. Seddon, David A. Cretella, Joshua Eudy, Hana Winders, Kayla Antosz Pharm.D., Pamela Bailey, Majdi N. Al-Hasan

Faculty Publications

Objective:

To evaluate temporal trends in the prevalence of gram-negative bacteria (GNB) with difficult-to-treat resistance (DTR) in the southeastern United States. Secondary objective was to examine the use of novel β-lactams for GNB with DTR by both antimicrobial use (AU) and a novel metric of adjusted AU by microbiological burden (am-AU). Design:

Retrospective, multicenter, cohort. Setting:

Ten hospitals in the southeastern United States. Methods:

GNB with DTR including Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp. from 2015 to 2020 were tracked at each institution. Cumulative AU of novel β-lactams including ceftolozane/tazobactam, ceftazidime/avibactam, meropenem/vaborbactam, imipenem/cilastatin/relebactam, and cefiderocol in days of therapy (DOT) …