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Articles 1531 - 1560 of 16088
Full-Text Articles in Entire DC Network
Motivational Dysregulation With Melanocortin 4 Receptor Haploinsufficiency, Alex M. Steiner, Robert F. Roscoe, Rosemarie M. Booze, Charles F. Mactutus
Motivational Dysregulation With Melanocortin 4 Receptor Haploinsufficiency, Alex M. Steiner, Robert F. Roscoe, Rosemarie M. Booze, Charles F. Mactutus
Faculty Publications
Obesity, by any standard, is a global health crisis. Both genetic and dietary contributions to the development and maintenance of obesity were integral factors of our experimental design. As mutations of the melanocortin 4 receptors (MC4R) are the leading monogenetic cause of obesity, MC4R haploinsufficient rats were fed a range of dietary fat (0–12 %) in a longitudinal design. Physiological and motivational assessments were performed using a locomotor task, a 5-choice sucrose preference task, an operant task with fixed and progressive ratios, as well as a distraction operant task. Dendritic spine morphology of medium spiny neurons (MSNs) of the nucleus …
Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude
Mediator Kinase Inhibitors Suppress Triple-Negative Breast Cancer Growth And Extend Tumor Suppression By Mtor And Akt Inhibitors, Xiaokai Ding, Jiaxin Liang, Amanda C. Sharko, Thomas A. Hilimire, Jing Li, Jürgen Loskutov, Zachary T. Mack, Hao Ji, Gary P. Schools, Chao Cai, Elena N. Pugacheva, Mengqian Chen, Igor Roninson, Eugenia Broude
Faculty Publications
Triple-negative breast cancers (TNBC) are treated primarily by chemotherapy and lack clinically validated therapeutic targets. In particular, inhibitors of the PI3K/AKT/mTOR pathway, abnormally activated in many breast cancers, failed to achieve clinical efficacy in TNBC due to the development of adaptive drug resistance, which is largely driven by the transcriptomic plasticity of TNBC. Expression of CDK8/19 Mediator kinases that control transcriptional reprogramming correlates with relapse-free survival and treatment failure in breast cancer patients, including TNBC. We now investigated how CDK8/19 inhibitors affect the growth of TNBC tumors and their response to mTOR and AKT inhibitors. In contrast to the effects …
Rural-Urban Disparities And Trends In Cancer Screening: An Analysis Of Behavioral Risk Factor Surveillance System Data (2018-2022), Gabriel A. Benavidez, Ami E. Sedani, Tisha M. Felder Phd, Msw, Matthew Asare, Charles R. Rogers
Rural-Urban Disparities And Trends In Cancer Screening: An Analysis Of Behavioral Risk Factor Surveillance System Data (2018-2022), Gabriel A. Benavidez, Ami E. Sedani, Tisha M. Felder Phd, Msw, Matthew Asare, Charles R. Rogers
Publications
Background
Despite evidence of the benefit of routine cancer screenings, data show a concerning decline in cancer screening uptake for multiple cancers. This analysis aimed to examine rural-urban differences in recent trends for being up-to-date with screenings for breast, cervical, and colorectal cancers.
Methods
We used 2018, 2020, and 2022 Behavioral Risk Factor Surveillance System data to assess up-to-date cancer screening status among eligible adults in the United States. We calculated weighted prevalence estimates overall and stratified by county-level rural-urban classification. We used survey-weighted multivariable logistic regression models to examine rural-urban disparities in cancer screening up-to-date status by year.
Results …
Rural-Urban Disparities And Trends In Cancer Screening: An Analysis Of Behavioral Risk Factor Surveillance System Data (2018-2022), Gabriel A. Benavidez, Ami E. Sedani, Tisha Moniek Felder Phd, Msw, Matthew Asare, Charles R. Rogers
Rural-Urban Disparities And Trends In Cancer Screening: An Analysis Of Behavioral Risk Factor Surveillance System Data (2018-2022), Gabriel A. Benavidez, Ami E. Sedani, Tisha Moniek Felder Phd, Msw, Matthew Asare, Charles R. Rogers
Faculty Publications
Background
Despite evidence of the benefit of routine cancer screenings, data show a concerning decline in cancer screening uptake for multiple cancers. This analysis aimed to examine rural-urban differences in recent trends for being up-to-date with screenings for breast, cervical, and colorectal cancers.
Methods
We used 2018, 2020, and 2022 Behavioral Risk Factor Surveillance System data to assess up-to-date cancer screening status among eligible adults in the United States. We calculated weighted prevalence estimates overall and stratified by county-level rural-urban classification. We used survey-weighted multivariable logistic regression models to examine rural-urban disparities in cancer screening up-to-date status by year.
Results …
State Divorce Laws, Reproductive Care Policies, And Pregnancy-Associated Homicide Rates, 2018-2021, Kaitlin M. Boyle, Wendy Regoeczi, Chase B. Meyer
State Divorce Laws, Reproductive Care Policies, And Pregnancy-Associated Homicide Rates, 2018-2021, Kaitlin M. Boyle, Wendy Regoeczi, Chase B. Meyer
Faculty Publications
Importance: Barriers to divorce and reproductive health care can threaten the health and safety of pregnant and recently pregnant females.
Objective: To examine state laws about divorce, reproductive health care (access to contraception, family planning services, and abortion), and pregnancy-associated homicide rates in US states over a 4-year period (2018-2021).
Design, Setting, and Participants: In this cross-sectional study, bivariate tests and regressions were used to analyze crude rates of pregnancy-associated homicide from the National Violent Death Reporting System in 181 state-years for calendar years 2018 to 2021, with analyses conducted on September 8, 2024.
Exposures: Access to divorce while pregnant …
Single-Molecule Profiling Of Per- And Polyfluoroalkyl Substances By Cyclodextrin Mediated Host-Guest Interactions Within A Biological Nanopore, Xiaojun Wei, Aditya Choudhary, Leon Y. Wang, Lixing Yang, Mark J. Uline, Mario Tagliazucchi, Qian Wang, Dmitry Bedrov, Chang Liu
Single-Molecule Profiling Of Per- And Polyfluoroalkyl Substances By Cyclodextrin Mediated Host-Guest Interactions Within A Biological Nanopore, Xiaojun Wei, Aditya Choudhary, Leon Y. Wang, Lixing Yang, Mark J. Uline, Mario Tagliazucchi, Qian Wang, Dmitry Bedrov, Chang Liu
Faculty Publications
Biological nanopores are increasingly used in molecular sensing due to their single-molecule sensitivity. The detection of per- and polyfluoroalkyl substances (PFAS) like perfluorooctanoic acid and perfluorooctane sulfonic acid is critical due to their environmental prevalence and toxicity. Here, we investigate selective interactions between PFAS and four cyclodextrin (CD) variants (α-, β-, γ-, and 2-hydroxypropyl-γ-CD) within an α-hemolysin nanopore. We demonstrate that PFAS molecules can be electrochemically sensed by interacting with a γ-CD in a nanopore. Using HP-γ-CDs with increased steric resistance, we can identify homologs of the perfluoroalkyl carboxylic acid and the perfluoroalkyl sulfonic acid families and detect common PFAS …
Benchmarking Machine Learning Models To Predict Low Birthweight Baby Outcomes And Identify Associated Risk Factors From An Extremely Unbalanced Large-Scale Dataset, Yang Ren, Dezhi Wu, Yan Tong Ph.D., Ana Lopez-De Fede Ph.D., Sarah J. Gareau
Benchmarking Machine Learning Models To Predict Low Birthweight Baby Outcomes And Identify Associated Risk Factors From An Extremely Unbalanced Large-Scale Dataset, Yang Ren, Dezhi Wu, Yan Tong Ph.D., Ana Lopez-De Fede Ph.D., Sarah J. Gareau
Publications
Background: Low birthweight (LBW) is one of the leading causes of neonatal mortality in the United States (US), and also is a major causative factor of short- and long-term adverse health effects in newborns. To prevent adverse birth outcomes, it is critical to precisely predict and identify which mothers are at high risk of bearing LBW babies in the early stage of their pregnancy. Previous studies proposed various LBW prediction models from different ML algorithms primarily on small datasets. However, their model performance is significantly limited by data access barriers and data quality issues with one major technical challenge of …
Revitalizing The Curriculum Collection: A Collaborative Partnership Approach, Kimberly T. Foster, Eric Resnis
Revitalizing The Curriculum Collection: A Collaborative Partnership Approach, Kimberly T. Foster, Eric Resnis
South Carolina Libraries
As K-12 education has increasingly focused on standardized testing, university curriculum centers have had to adjust their holding to offer more curricula-focused material. These collections can be vital for the development of pre-service teachers, who often need access to the learning materials that they will later use. This article explores the steps taken by a university library to revitalize a curriculum collection in order to offer more curriculum-based holdings for pre-service teachers to use.
Sculpting Success: The Importance Of Diet And Physical Activity To Support Skeletal Muscle Health During Weight Loss With New Generation Anti-Obesity Medications, Gregory J. Grosicki, Nikhil V. Dhurandhar, Jessica L. Unick, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, J. Graham Thomas, Holly Lofton, Madelyn C. Shepherd, Jessica Kiel, Christopher Coleman, Satya S. Jonnalagadda
Sculpting Success: The Importance Of Diet And Physical Activity To Support Skeletal Muscle Health During Weight Loss With New Generation Anti-Obesity Medications, Gregory J. Grosicki, Nikhil V. Dhurandhar, Jessica L. Unick, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, J. Graham Thomas, Holly Lofton, Madelyn C. Shepherd, Jessica Kiel, Christopher Coleman, Satya S. Jonnalagadda
Faculty Publications
Obesity is a public health crisis, with prevalence rates tripling over the past 60 y. Although lifestyle modifications, such as diet and physical activity, remain the first-line treatments, recent anti-obesity medications (AOMs) have been shown to achieve greater reductions in body weight and fat mass. However, AOMs also reduce fat-free mass, including skeletal muscle, which has been demonstrated to account for 20% to 50% of total weight loss. This can equate to ∼6 kg or 10% of total lean mass after 12–18 mo, a loss comparable to a decade of human aging. Despite questions surrounding the clinical relevance of weight …
Identifying Ordinal Categories For The Water Insecurity Experiences Scales, Edward A. Frongillo Jr., Hilary J. Bethancourt, Joshua D. Miller, Sera L. Young, The Household Water Insecurity Experiences Scales (Hwise)-Research Coordination Network (Rcn)
Identifying Ordinal Categories For The Water Insecurity Experiences Scales, Edward A. Frongillo Jr., Hilary J. Bethancourt, Joshua D. Miller, Sera L. Young, The Household Water Insecurity Experiences Scales (Hwise)-Research Coordination Network (Rcn)
Faculty Publications
The Household Water Insecurity Experiences (HWISE) and Individual Water Insecurity Experiences (IWISE) Scales are globally suitable tools for comparably measuring water insecurity experiences among households and adults, respectively. The potential range for HWISE and IWISE scores is 0–36. When the WISE Scales were first published, scores of 12 and higher were considered indicative of water insecurity, but additional cut-points are needed to provide more nuanced insights. We therefore sought to develop a practical set of cut-points for the WISE Scales using HWISE data from 13 sites across 12 countries (n = 3,293) and nationally representative samples of IWISE data …
Characterization Of Health And Safety Resources For Athletes With Sickle Cell Trait At Ncaa Institutions, Susan W. Yeargin Ph.D., Atc, Lat, Courtney M. Meyer Ph.D., Rebecca M. Hirschhorn, Abbi D. Lane, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Clint R. Haggard
Characterization Of Health And Safety Resources For Athletes With Sickle Cell Trait At Ncaa Institutions, Susan W. Yeargin Ph.D., Atc, Lat, Courtney M. Meyer Ph.D., Rebecca M. Hirschhorn, Abbi D. Lane, Shawn M. Arent Ph.D., Cscs*D, Fissn, Facsm, Fnak, Clint R. Haggard
Faculty Publications
Yeargin, SW, Meyer, CM, Hirschhorn, RM, Lane, AD, Arent, SM, and Haggard, CR. Characterization of health and safety resources for athletes with sickle cell trait at NCAA institutions. J Strength Cond Res 38(11): 1967-1973, 2024 - The purpose of this study was to report the prevalence of student-athletes with sickle cell trait (SCT), determine which screening practices are most commonly used, describe the health and human performance services provided to athletes, and ascertain if differences between National Collegiate Athletic Association (NCAA) designations or divisions exist. A cross-sectional survey design was used to query healthcare administrators regarding SCT resources at their …
World Delirium Wareness And Quality Survey In 2023- A Worldwide Point Prevalence Study, Heidi Lindroth, Keibun Liu, Laura Szalacha, Giuseppe Bellelli, Mark Von Den Boogaard, Gideon Caplan, Chi Ryang Chung, Muhammed Elhadi, Mohan Gurjar, Gabriel Heras-La-Calle, Magdalena Hoffman, Marie-Madlen Jeitziner, Karla Krewulak, Tanja Mailhot, Alessandro Morandi, Ricardo Kenji Nawa, Esther S. Oh, Marie Oxenboell Collet, Rebecca Von Haken, Peter Nydahl, For The Wdad Study Team
World Delirium Wareness And Quality Survey In 2023- A Worldwide Point Prevalence Study, Heidi Lindroth, Keibun Liu, Laura Szalacha, Giuseppe Bellelli, Mark Von Den Boogaard, Gideon Caplan, Chi Ryang Chung, Muhammed Elhadi, Mohan Gurjar, Gabriel Heras-La-Calle, Magdalena Hoffman, Marie-Madlen Jeitziner, Karla Krewulak, Tanja Mailhot, Alessandro Morandi, Ricardo Kenji Nawa, Esther S. Oh, Marie Oxenboell Collet, Rebecca Von Haken, Peter Nydahl, For The Wdad Study Team
Publications
Background
Delirium, an acute brain dysfunction, is proposed to be highly prevalent in clinical care and shown to significantly increase the risk of mortality and dementia.
Objectives
To report on the global prevalence of clinically documented delirium and delirium-related clinical practices in wards caring for paediatric and adult patients in healthcare facilities.
Design
A prospective, cross-sectional, 39-question survey completed on World Delirium Awareness Day, 15 March 2023.
Participants
Clinicians or researchers with access to clinical data.
Main Outcome and Measure
The primary outcome was the prevalence of clinically documented delirium at 8:00 a.m. (4 h) and 8:00 p.m. (±4 h). …
Adverse Childhood Experiences And Hiv-Related Stigma: A Quantitative Survey Of Tanzanian Men, June 2019, Amandeep Kaur, Monique J. Brown Ph.D., Mph, Geoffrey K. Kangogo, Xiaoming Li Ph.D., Ivan E. Teri, Gaspar Mbita, Aima A. Ahonkhai, Donaldson F. Conserve
Adverse Childhood Experiences And Hiv-Related Stigma: A Quantitative Survey Of Tanzanian Men, June 2019, Amandeep Kaur, Monique J. Brown Ph.D., Mph, Geoffrey K. Kangogo, Xiaoming Li Ph.D., Ivan E. Teri, Gaspar Mbita, Aima A. Ahonkhai, Donaldson F. Conserve
Faculty Publications
Experiencing adverse childhood experiences (ACEs) may impact personal opinions, attitudes, and judgments, which can further result in HIV-related stigma. HIV-related stigma consequentially may impact HIV preventive measures such as HIV testing, pre-exposure prophylaxis uptake, and condom use. The extent to which ACEs influence HIV-related stigma perception has not been well studied. Therefore, the study aimed to examine the association between ACEs and perceived and interpersonal HIV-related stigma among Tanzanian HIV-negative men. Quantitative survey data were obtained from the Tanzania STEP (Self-Testing Education and Promotion) project established in four wards: Mabibo, Manzese, Tandale, and Mwanyanamala. A total of 507 men responded …
How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton Ma, Lmsw, Simone Kabarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.
How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton Ma, Lmsw, Simone Kabarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.
Faculty Publications
Background: The concept of health literacy (HL) is constantly evolving, and social determinants of health (SDoH) have been receiving considerable attention in public health scholarship. Since a 1-size-fits-all approach for HL fails to account for multiple contextual factors and as a result poses challenges in improving literacy levels, there is a need to develop a deeper understanding of the current state of HL and digital health literacy (DHL) research. Objective: This study examined scholars’ conceptualization and scope of work focused on HL and DHL. Methods: Using a search string, investigators (N=2042) focusing on HL, DHL, or both were identified from …
How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? A Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton, Simon Kavarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent Rd, Mph, Cscs, Cissn, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.
How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? A Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton, Simon Kavarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent Rd, Mph, Cscs, Cissn, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.
Publications
Background: The concept of health literacy (HL) is constantly evolving, and social determinants of health (SDoH) have been receiving considerable attention in public health scholarship. Since a 1-size-fits-all approach for HL fails to account for multiple contextual factors and as a result poses challenges in improving literacy levels, there is a need to develop a deeper understanding of the current state of HL and digital health literacy (DHL) research.
Objective: This study examined scholars’ conceptualization and scope of work focused on HL and DHL.
Methods: Using a search string, investigators (N=2042) focusing on HL, DHL, or both were identified from …
Modeling Reversible Volume Change In Automotive Battery Cells With Porous Silicon Oxide-Graphite Composite Anodes, Taylor R. Garrick, Brian J. Koch, Miguel A. Fernandez, Erin Efimoff, Hunter Teel, Matthew D. Jones, Mingjie Tu, Sirivatch Shimpalee
Modeling Reversible Volume Change In Automotive Battery Cells With Porous Silicon Oxide-Graphite Composite Anodes, Taylor R. Garrick, Brian J. Koch, Miguel A. Fernandez, Erin Efimoff, Hunter Teel, Matthew D. Jones, Mingjie Tu, Sirivatch Shimpalee
Faculty Publications
Automotive battery manufacturers are working to improve the individual cell and overall pack design by increasing durability, performance, and range, while reducing cost, and active material volume change is a key aspect that needs to be considered during this design process. Recently, silicon oxide-graphite composite anodes are being explored to increase total anode capacity while maintaining a tolerable amount of cell level reversible volume expansion due to the relatively lower reversible volume change of the silicon oxide compared to pure battery grade or metallurgical grade silicon. To predict the blended anode response and contribution to the overall cell volume change, …
The Mental Health Literacy Of Ncaa College Coaches: Knowledge, Beliefs, And Resources, Lauren Beasley, Steven Hoffman, Jackson Sears
The Mental Health Literacy Of Ncaa College Coaches: Knowledge, Beliefs, And Resources, Lauren Beasley, Steven Hoffman, Jackson Sears
Journal of Issues in Intercollegiate Athletics
National Collegiate Athletic Association (NCAA) college athletes in the United States (U.S.) are at risk for diminished mental health, and stigma may be a barrier to these athletes seeking professional mental health care. Coaches can create a team environment that prioritizes athlete mental health and destigmatizes help-seeking; however, this requires coaches to have appropriate mental health knowledge, operationalized as mental health literacy (MHL). Therefore, the purpose of this exploratory study was to explore three different constructs of MHL of NCAA coaches across Divisions I, II, and III. The Multicomponent Mental Health Literacy Scale (MMHLS), which measures MHL within three domains—knowledge, …
Evaluation And Lessons Learned From The Dissemination And Implementation Science Scholars Program In The National Cancer Prevention And Control Research Network, Daniela B. Friedman, Cam Escoffery, Elaine H. Morrato, Cynthia A. Thomson, Courtney N. Petagna, Freda Allyson Hucek, Mary Wangen, Aubrey Villalobos, James R. Hébert Scd, Samuel Noblet, Mayank Sakhuja, David O. Garcia, Jennifer L. Cruz, Stephanie B. Wheeler
Evaluation And Lessons Learned From The Dissemination And Implementation Science Scholars Program In The National Cancer Prevention And Control Research Network, Daniela B. Friedman, Cam Escoffery, Elaine H. Morrato, Cynthia A. Thomson, Courtney N. Petagna, Freda Allyson Hucek, Mary Wangen, Aubrey Villalobos, James R. Hébert Scd, Samuel Noblet, Mayank Sakhuja, David O. Garcia, Jennifer L. Cruz, Stephanie B. Wheeler
Faculty Publications
Background:
The Centers for Disease Control and Prevention (CDC)-funded Cancer Prevention and Control Research Network (CPCRN) has been a leader in cancer-related dissemination & implementation (D&I) science. Given increased demand for D&I research, the CPCRN Scholars Program launched in 2021 to expand the number of practitioners, researchers, and trainees proficient in cancer D&I science methods. Methods:
The evaluation was informed by a logic model and data collected through electronic surveys. Through an application process (baseline survey), we assessed scholars’ competencies in D&I science domains/subdomains, collected demographic data, and asked scholars to share proposed project ideas. We distributed an exit survey …
Delirium In The United States: Results From The 2023 Cross-Sectional World Delirium Awareness Day Prevalence Study, Heidi Lindroth, Tru Byrnes, Mikita Fuchita, Breanna Hetland, Keibun Liu, Kerri Maya, Natalie S. Mcandrew, Malissa A. Mulkey Phd, Aprn, Ccns, Ccrn, Cnrn, Peter Nydahl, Jessica Palakshappa, Rebecca Von Haken, Kevin J. Psoter, Esther S. Oh, U.S. Wdad Team, Elizabeth Anderson, Lillian Banchero, Dianne Bettic, Lane Branch, Katie Brown, Et. Al
Delirium In The United States: Results From The 2023 Cross-Sectional World Delirium Awareness Day Prevalence Study, Heidi Lindroth, Tru Byrnes, Mikita Fuchita, Breanna Hetland, Keibun Liu, Kerri Maya, Natalie S. Mcandrew, Malissa A. Mulkey Phd, Aprn, Ccns, Ccrn, Cnrn, Peter Nydahl, Jessica Palakshappa, Rebecca Von Haken, Kevin J. Psoter, Esther S. Oh, U.S. Wdad Team, Elizabeth Anderson, Lillian Banchero, Dianne Bettic, Lane Branch, Katie Brown, Et. Al
Publications
Background: Delirium is an acute brain dysfunction associated with an increased risk of mortality and future dementia. Objectives: To describe the prevalence of clinically documented delirium in the United States on World Delirium Awareness Day 2023. Methods: This is a sub-analysis of a prospective, crosssectional, online, international survey. All health care settings were eligible, with the exception of operating rooms and outpatient clinics. Health care clinicians, administrators, and researchers completed the survey. The primary outcome was the prevalence of clinically documented delirium at 8:00 a.m. and 8:00 p.m. on March 15, 2023. Secondary outcomes were related to health care delivery. …
Garnet & Black: Fall 2024, University Of South Carolina, Office Of Student Media
Garnet & Black: Fall 2024, University Of South Carolina, Office Of Student Media
Garnet & Black Magazine
No abstract provided.
Mutation In Prkra Results In Cerebellar Abnormality And Reduced Elf2Α Phosphorylation In A Model Of Dyt-Prkra, Samuel B. Burnett, Allison M. Culver, Tricia A. Simon, Taylor Rowson, Kenneth Frederick, Kristina Palmer, Stephen A. Murray, Shannon W. Davis
Mutation In Prkra Results In Cerebellar Abnormality And Reduced Elf2Α Phosphorylation In A Model Of Dyt-Prkra, Samuel B. Burnett, Allison M. Culver, Tricia A. Simon, Taylor Rowson, Kenneth Frederick, Kristina Palmer, Stephen A. Murray, Shannon W. Davis
Faculty Publications
Variants in the PRKRA gene, which encodes PACT, cause the early-onset primary dystonia DYT-PRKRA, a movement disorder associated with disruption of coordinated muscle movements. PACT and its murine homolog RAX activate protein kinase R (PKR; also known as EIF2AK2) by a direct interaction in response to cellular stressors to mediate phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α). Mice homozygous for a naturally arisen, recessively inherited frameshift mutation, Prkralear-5J, exhibit progressive dystonia. In the present study, we investigated the biochemical and developmental consequences of the Prkralear-5J mutation. Our results indicated that the …
Influence Of Redox Engineering On The Trade-Off Relationship Between Thermopower And Electrical Conductivity In Lanthanum Titanium Based Transition Metal Oxides, Mohammad El Loubani, Gene Yang, Seyed Morteza Taghavi Kouzehkanan, Tae-Sik Oh, Santosh Kiran Balijepalli, Dongkyu Lee
Influence Of Redox Engineering On The Trade-Off Relationship Between Thermopower And Electrical Conductivity In Lanthanum Titanium Based Transition Metal Oxides, Mohammad El Loubani, Gene Yang, Seyed Morteza Taghavi Kouzehkanan, Tae-Sik Oh, Santosh Kiran Balijepalli, Dongkyu Lee
Faculty Publications
Discovery of new materials plays a critical role in developing advanced high-temperature thermoelectric (TE) applications. Transition metal oxides (TMOs) are one of the attractive candidates for high-temperature TE applications due to their thermal and chemical stability. However, the trade-off relationship between thermopower (S) and electrical conductivity (σ) limits the maximum attainable power factor (PF), thereby hindering improvements in TE conversion efficiency. To overcome this trade-off relationship, the emerging approach of the redox-driven metal exsolution in TMOs shows promise in improving both S and σ. However, the effect of metal exsolution with different particle sizes and …
Exploring The Association Between Parenting Stress And A Child’S Exposure To Positive Childhood Experiences (Pces), Elizabeth Crouch Ph.D., Elizabeth Radcliff, Monique J. Brown Ph.D., Mph, Peiyin Hung Ph.D
Exploring The Association Between Parenting Stress And A Child’S Exposure To Positive Childhood Experiences (Pces), Elizabeth Crouch Ph.D., Elizabeth Radcliff, Monique J. Brown Ph.D., Mph, Peiyin Hung Ph.D
Faculty Publications
High levels of parenting stress, defined as a caregiver or parent feeling stress or aggravation from parenting, has been previously shown to be associated with an increased likelihood of neglect, child maltreatment, and household dysfunction: adverse childhood experiences (ACEs). Despite the potential mitigation of positive childhood experiences (PCEs) on ACEs, prior studies on the increased likelihood of a child experiencing ACEs due to parenting stress have left a critical question unanswered: whether high parenting stress may decrease a child’s likelihood of experiencing PCEs. We analyzed the 2019–2020 National Survey of Children’s Health to examine whether higher levels of parenting stress …
Social Isolation And Loneliness Prevention Among Rural Older Adults Aging-In-Place: A Needs Assessment, Jodi L. Southerland, Shimin Zheng, Kayla Dodson, Erin Mauck, Juanita-Dawne R. Bacsu, Monique J. Brown Ph.D., Mph, Jeremy Holloway, Steffi M. Kim, Ayse Malatyali, Matthew Lee Smith
Social Isolation And Loneliness Prevention Among Rural Older Adults Aging-In-Place: A Needs Assessment, Jodi L. Southerland, Shimin Zheng, Kayla Dodson, Erin Mauck, Juanita-Dawne R. Bacsu, Monique J. Brown Ph.D., Mph, Jeremy Holloway, Steffi M. Kim, Ayse Malatyali, Matthew Lee Smith
Faculty Publications
Introduction: The adverse effects of social isolation and loneliness (SI/L) have been documented among older adults in rural communities and contribute to poor health outcomes, premature disability and mortality, and increased burden on the healthcare system. The identification of factors contributing to SI/L among older adults can build the foundation for rural policymakers and leaders to allocate resources and develop tailored strategies more efficiently. The purpose of this article is to describe findings from a needs assessment designed to understand local factors that contribute to SI/L among rural older adults in a county in Northeast Tennessee. Findings from the needs …
The Daily Gamecock: October 2024, University Of South Carolina, Office Of Student Media
The Daily Gamecock: October 2024, University Of South Carolina, Office Of Student Media
October
No abstract provided.
How Has Health Literacy And Digital Health Literacy Scholarship Evolved? A Global, Qualitative Study, Brooks Yelton Ma, Lmsw, Mayank Sakhuja, Simone Kavarana, Lauren Schaurer, Michelle Angelique Arent, Lorie Donelle Phd, Rn, Fcan, Mark M. Macauda, Samuel Noblet, Daniela B. Friedman
How Has Health Literacy And Digital Health Literacy Scholarship Evolved? A Global, Qualitative Study, Brooks Yelton Ma, Lmsw, Mayank Sakhuja, Simone Kavarana, Lauren Schaurer, Michelle Angelique Arent, Lorie Donelle Phd, Rn, Fcan, Mark M. Macauda, Samuel Noblet, Daniela B. Friedman
Publications
Health literacy (HL) is a key social determinant of health (SDoH) and is of increasing importance in public health research and intervention for improved health outcomes. Definitions of HL and digital health literacy (DHL) have evolved over time as the field has expanded conceptualization from an individual focus to the broader community and organizational levels. Careful consideration of HL and DHL for a variety of contexts and audiences is critical given increased global adoption of digital technologies and responses to emerging public health challenges. This study aimed to capture researchers' conceptualizations of HL/DHL and their motivations to engage in this …
Physical Development And Sociocultural Context Influences On Children’S Physical Activity, Alessandro Hervaldo Nicolai Ré, Maria Teresa Cattuzzo, David F. Stodden Ph.D., Guilherme Dos Santos, Albert Lucas Olinto Tertuliano, Carlos Bandeira De Mello Monteiro, Diogo Henrique Constantino Coledam, Anthony David Okely
Physical Development And Sociocultural Context Influences On Children’S Physical Activity, Alessandro Hervaldo Nicolai Ré, Maria Teresa Cattuzzo, David F. Stodden Ph.D., Guilherme Dos Santos, Albert Lucas Olinto Tertuliano, Carlos Bandeira De Mello Monteiro, Diogo Henrique Constantino Coledam, Anthony David Okely
Faculty Publications
Objective:
To examine the predictive strength of cardiorespiratory fitness (CRF), motor competence (MC), maternal educational status, and parental perception of their children’s favorite leisure activities for meeting physical activity (PA) guidelines of each gender among children aged 3–6 years.
Methods: This is a cross-sectional study with 367 preschoolers (53% girls), assessing CRF (PREFIT 20m shuttle run), MC (battery of motor skills), PA (accelerometry), maternal education and parental perception of children’s preferred leisure (questionnaires). Factorial analysis of covariance, multiple logistic regression, and chi-square tests were conducted.
Results: In both genders, CRF was associated with meeting PA guidelines (girls: odds ratio [OR] …
Adding The Third Dimension: 3d Convolutional Neural Network Diagnosis Of Temporal Lobe Epilepsy, Erik Kaestner, Reihaneh Hassanzadeh, Ezequiel Gleichgerrcht, Kyle Hasenstab, Rebecca W. Roth, Allen Chang, Theodor Rüber, Kathryn A. Davis, Patricia Dugan, Ruben Kuzniecky, Julius Fridriksson Ph.D., Alexandra Parashos, Anto I. Bagić, Daniel L. Drane, Simon S. Keller, Vince D. Calhoun, Anees Abrol, Leonardo Bonilha, Carrie R. Mcdonald
Adding The Third Dimension: 3d Convolutional Neural Network Diagnosis Of Temporal Lobe Epilepsy, Erik Kaestner, Reihaneh Hassanzadeh, Ezequiel Gleichgerrcht, Kyle Hasenstab, Rebecca W. Roth, Allen Chang, Theodor Rüber, Kathryn A. Davis, Patricia Dugan, Ruben Kuzniecky, Julius Fridriksson Ph.D., Alexandra Parashos, Anto I. Bagić, Daniel L. Drane, Simon S. Keller, Vince D. Calhoun, Anees Abrol, Leonardo Bonilha, Carrie R. Mcdonald
Faculty Publications
Convolutional neural networks (CNN) show great promise for translating decades of research on structural abnormalities in temporal lobe epilepsy into clinical practice. Three-dimensional CNNs typically outperform two-dimensional CNNs in medical imaging. Here we explore for the first time whether a three-dimensional CNN outperforms a two-dimensional CNN for identifying temporal lobe epilepsy-specific features on MRI. Using 1178 T1-weighted images (589 temporal lobe epilepsy, 589 healthy controls) from 12 surgical centres, we trained 3D and 2D CNNs for temporal lobe epilepsy versus healthy control classification, using feature visualization to identify important regions. The 3D CNN was compared to the 2D model and …
October 9, 2024 Faculty Senate Minutes, University Of South Carolina
October 9, 2024 Faculty Senate Minutes, University Of South Carolina
Faculty Senate
No abstract provided.
Development Of Prediction Models Of Covid-19 Vaccine Uptake Among Lebanese And Syrians In A District Of Beirut, Lebanon: A Population-Based Study, Marie-Elizabeth Ragi, Hala Ghattas Ph.D., Hazar Shamas, Jocelyn Dejong, Nada M. Melhem, Stephen J. Mccall, The Caep Study Group
Development Of Prediction Models Of Covid-19 Vaccine Uptake Among Lebanese And Syrians In A District Of Beirut, Lebanon: A Population-Based Study, Marie-Elizabeth Ragi, Hala Ghattas Ph.D., Hazar Shamas, Jocelyn Dejong, Nada M. Melhem, Stephen J. Mccall, The Caep Study Group
Faculty Publications
Introduction Vaccines are essential to prevent infection and reduce the morbidity of infectious diseases. Previous evidence has shown that migrants and refugees are particularly vulnerable to exclusion and discrimination, and low COVID-19 vaccine intention and uptake were observed among refugees globally. This study aimed to develop and internally validate prediction models of COVID-19 vaccine uptake by nationality.
Methods This is a nested prognostic population-based cross-sectional analysis. Data were collected between June and October 2022 in Sin-El-Fil, a district of Beirut, Lebanon. The study population included a random sample of Lebanese adults and all Syrian adults residing in areas of low …