Digital Commons Network^™

The Left Ventricle Under Stress: Exploring The Impact Of Gestational Stress On Postpartum Cardiovascular Health, Archana Ramesh

Senior Theses

A woman’s cardiovascular system undergoes several changes to equip it for the physiological demands of pregnancy. The left ventricle (LV) is most susceptible to changes such as increased cardiac output and workload because it is the primary chamber in the heart that pumps oxygenated blood to the entire body. Some mothers may be unable to cope with the physiological demands, and ventricular hypertrophy, along with other cardiac remodeling that takes place during pregnancy, may bring light to underlying cardiovascular disease (CVD). The peripartum period often comes with heightened stress, disproportionately for certain populations, and this stress has been linked with …

Understanding Patterns Of Hope And Sense Of Belonging From Mentoring Through Latent Class Analysis, Bailey Dow

Theses and Dissertations

Youth who have safe, stable, nurturing relationships (SSNRs) are more resilient to adverse childhood experiences and have better mental health. Compared to prior generations, today’s youth feel lonelier and more socially isolated than ever, and they crave the sense of belonging and hope that comes from meaningful social connections. Mentors can play a crucial role in bolstering these attributes. Mentors help youth in different ways, depending on the mentee's characteristics, preferences, or circumstances. Despite the well-known significance of natural mentoring relationships as a SSNR, researchers have paid little attention to how and why natural mentoring benefits vary among mentees. The …

Juries And Tax: The Effect Of Income Taxation On Tort Damages, Jeffrey H. Kahn, John E. Lopatka

South Carolina Law Review

No abstract provided.

Infringing Uses, Not Works, Timothy J. Mcfarlin

South Carolina Law Review

No abstract provided.

A Low Density Tracker For The Dune Nd Complex., Nibir Talukdar

Theses and Dissertations

The Deep Underground Neutrino Experiment (DUNE) is a next-generation long- baseline neutrino experiment aimed at resolving mass hierarchy and the CP violation puzzle in the neutrino sector. Although neutrinos are the most abundant particles in the universe, their study is challenging due to their extremely low interaction cross sections. DUNE aims to overcome these challenges by sending a beam of muon (anti)neutrinos from Fermilab, located near Chicago, to the Sanford Underground Research Facility (SURF) in South Dakota.

The experiment consists of a near detector (ND) complex at Fermilab, which mea- sures the composition of the unoscillated neutrino beam, and a …

Enhancing Inclusivity In Primary Care On A College Campus, Amanda Finkle Plyler

Doctor of Nursing Practice Scholarly Projects

Problem Statement: Individuals who identify as lesbian, gay, bisexual, transgender, and queer or questioning (LGBTQ+) face higher health disparities and are less likely to seek healthcare due to fear of being misgendered or judged by staff. Purpose: The purpose of this DNP project was to implement an intervention for college students seeking care at Student Health Services (SHS) that includes a question addressing preferred pronouns during establishment of care, creating the opportunity for staff to address patients appropriately and to provide gender-affirming care. Method(s): A pre and post intervention patient satisfaction survey related to sexual orientation and gender identity (SOGI), …

The Impact Of A Visual Remote Patient Monitoring Device (Leaf) On Hospital-Acquired Pressure Injuries (Hapi), Tyler Andrew Gunther

Doctor of Nursing Practice Scholarly Projects

Problem Statement: The Critical Care Department at a large academic hospital in the Southeast has experienced a significant increase in healthcare-acquired pressure injuries (HAPIs), contributing to elevated mortality rates. Factors such as insufficient adherence to turning protocols and resource limitations impact patient safety, thus increasing the potential for adverse outcomes and increased costs. Purpose: The purpose of this DNP scholarly project was to evaluate the impact of a turn monitoring device, specifically the LEAF system by Smith and Nephew, on HAPI incidence in the critical care setting. The project aimed to address the identified barriers to compliance, enhance patient safety, …

Increasing Pre-Procedure Communications To Decrease Colonoscopy Cancellations, Natalie Brooke Midkiff

Doctor of Nursing Practice Scholarly Projects

Problem Statement: Colonoscopies play a vital role in early colorectal disease detection and prevention. Yet, the field of gastroenterology faces a persistent challenge - frequent procedure cancellations and incomplete examinations due to suboptimal bowel preparation. This not only compromises the effectiveness of colonoscopies but also poses potential health risks.

Purpose: This project aimed to reduce procedure cancellations and incomplete examinations by regularly communicating pre-procedure instructions and reminders through text messages and phone calls.

Inclusion Criteria: The criteria were clearly defined, targeting patients aged 18 and older who needed colonoscopies. This focus ensured the project's relevance to specialized gastrointestinal intervention. Establishing …

Regulation And Function Of The Rna-Binding Protein Khsrp During Neuronal Development, Regeneration And Axonal Injury Response, Courtney Nicole Buchanan

Theses and Dissertations

Axons, which extend long distances from neuronal cell bodies, rely on localized mRNA translation to swiftly respond to extracellular stimuli and physiological states. This work investigates the mechanism underlying the RNA-binding protein KHSRP’s, axonal mRNA translation and regulatory pathways involved in neuronal growth and regeneration. Our results indicate that KHSRP deletion in mice leads to upregulation of growth-associated mRNAs linked to neuronal morphology and function, resulting in increased axon growth and altered memory consolidation. Indicating a critical role for KHSRP in neuronal development and function through post-transcriptional regulation (Chapter 2). Additionally, we show there is a rapid increase in axonal …

Integrating Digital Twin Technology For Real Time Blockage Detection In Water Cooled Electronics, Richard Scott Hainey Jr.

Theses and Dissertations

This paper presents a culmination of research into integrating Digital Twin (DT) technology in water-cooled electronic systems to improve system reliability by detecting faults in the cooling system that maintains the proper operation of heat-producing electronic components and systems. A DT is a virtual representation of a physical twin (PT). This PT can represent real-world systems, individual components, or processes. Using the DT, operators can gain insight into the behavior and characteristics of the PT, thereby facilitating informed decisions to improve its health and optimize processes. The DT system is designed to detect obstructions forming in the waste heat-producing components …

The Importance Of Policing, Stephen Rushin

South Carolina Law Review

No abstract provided.

The Role Of Spatial Attention In The Maintenance Of Visual Working Memory: Modulatory Effect By Task-Relevance Of Spatial Information And Evidence From Alpha Oscillations, Sori Kim

Theses and Dissertations

The close interplay between spatial attention and visual working memory is essential for optimizing our visual experiences. The following studies investigated this interaction, focusing on how spatial attention influences visual working memory processes. In Chapter 2 a dual-task paradigm was used to examine how the relevance of spatial information to the task modulated the effects of spatial attention. The findings showed that shifting spatial attention away from a potential memory target impaired its consolidation in working memory. In Chapter 3, the experiment aimed to amplify these effects to observe clearer facilitatory and inhibitory processes. However, the results only demonstrated that …

Effect Of Storage Time And Temperature On Aggregation Of Alzheimer's Disease Amyloid-Β Protein, Amy Veihdeffer

Theses and Dissertations

Amyloid-β protein (Aβ) is widely studied due to its key role in Alzheimer’s disease (AD) pathology. One characteristic of patients suffering from AD is the deposition of amyloid plaques comprised of Aβ aggregates, which are associated with synapse damage. Thus, studying Aβ aggregation and aggregation inhibition may provide pathological and therapeutic insights. Aggregation of Aβ is a nucleation dependent process that may be influenced by the presence of pre-formed Aβ aggregate seeds that can facilitate formation of protein aggregates. These seeds may appear during preparation or storage of monomer, posing impact on experiments that study the aggregation process and the …

Interpretation Of Surface Roughness Of Stainless Steel 316l In Laser Powder Bed Fusion Additive Manufacturing, Tianyu Zhang

Theses and Dissertations

Laser Powder Bed Fusion (L-PBF), a widely used metal additive manufacturing (AM) method, is emerging as a key technology in the modern manufacturing industry. Its applications span across aerospace, transportation, energy, and biomedical industries, aiming to maximize product functionality, quality, and manufacturing efficiency.

Surface roughness, an important measure of product quality, impacts geometrical tolerances and plays a critical role in mechanical and functional properties. Although post-process techniques such as machining, shot peening, and chemical processing can be used to refine surfaces, internal surfaces in complex geometries remain difficult to treat, limiting part performance due to undesired surface features. The …

Retrospective Of My Experience At The University Of South Carolina, Karl Dickey

Theses and Dissertations

Theatre is, by its very nature, a collaborative process. No show lives in true isolation. Even in its smallest version, it takes at least one to perform and one to listen. The theatre that is produced in the 21^st century is deeper and more complex a process than the finished and polished shows that are presented to the audience. Behind, underneath, and all around a single performer on a stage are hours of thoughtful contemplation and execution on the part of the director, designers, and fabricators. There is something to be learned and gained from every human interaction in …

Bridging Disciplinary Boundaries: A Study On The Integration Of Social Studies Within Elementary Ela Education, Jill Knight

Theses and Dissertations

This qualitative action research study investigates the integration of social studies within English Language Arts (ELA) education, highlighting the challenges educators face in balancing curriculum demands amid increasing literacy and math instruction pressures. With over 20 years of experience teaching high school history, the researcher identified a concerning decline in social studies education at the elementary level, a situation worsened by legislative measures such as No Child Left Behind (NCLB) and the Every Student Succeeds Act (ESSA), which prioritize tested subjects. The primary aim of this study was to collaborate with elementary teachers to explore their perceptions and experiences related …

Investigating Student Engagement Through The Implementation Of A Performance Task In Secondary Mathematics: A Mixed Methods Action Research Study, Sulema Wright

Theses and Dissertations

Through teaching experiences in the math classroom, students voiced that solving mathematical problems did not benefit them in the real-world. This study discussed the use of a performance task in a high school geometry class as a way to engage students, increase their confidence when solving math problems, and determine the impact they have on engagement compared to supportive assignments. Students' perspectives were used as one measure in determining engagement, alongside, my perspective of using a tally table. Through the use of a performance task that connected to the life experiences, students’ perspectives proved that implementation increased their engagement in …

Inspecting The Foundations Of Natural Law Ethics And Politics: Looking For Cracks, Detecting Gaps, And Considering The Edifice That Can Be Built Thereon, Adam D. Bailey

Theses and Dissertations

In this dissertation I inspect the foundations of natural law ethics and politics. The inspection involves looking for cracks, detecting gaps, and considering the edifice that can be built thereon. To do so, I critically examine several of the many concepts and principles that are constitutive of those foundations. Some of my examination is done by means of direct consideration of such concepts and principles. And some of it is done by addressing such concepts and principles indirectly as I address questions about practical ethical or political concerns including: how can public officials make decisions that are not biased, what …

Temporal Forecasting Of High-Rate Dynamic Using Physics-Informed Machine Learning And Hardware-Software Co-Design, Puja Chowdhury

Theses and Dissertations

Due to aging, fatigue, corrosion, and even natural disasters; the health of the structure is prone to degradation throughout its service life. The explosively-fast growing efforts on Structural health monitoring (SHM) always try to exploit different aspects of the automation of damage detection, localization, and prognosis tasks. One of the main challenges is the hardware and software co-design to implement the model in real-life situations. On the other hand, the fast-advancing artificial intelligence draws the researchers' attention to adopt different data-driven approaches in this field. This brings other challenges like domain-specific model adaptation, data bias, data scarcity, model validation by …

Perceptions Of Virtual Reality In Cardiac Pharmacy Education, Morgan E. Mendes

Senior Theses

Background: The reformation of how educational content is portrayed is not a new phenomenon. However, the world of pharmacy has been slow to adapt, particularly considering higher education’s declining attendance rates and less engaging lectures. XR can be a great addition to learners’ curriculum, particularly VR, with various applications including adjunctive pharmacotherapy, patient counseling, pharmacist training, and pharmacological modeling. Despite the various barriers VR integration faces, the benefits of VR necessitate its future implementation into our COP curriculum as an augmentative form of learning.

Methods: An independent study of 11 students at the UofSC COP was conducted in the Spring …

Augmented Reality (Ar) And Virtual Reality (Vr)-Based Data Visualization Frameworks For The Manufacturing Industry, Nitol Saha

Theses and Dissertations

Industry 4.0 is transforming the manufacturing industry by integrating digital technologies throughout the production lifecycle, leading to the development of smart factories. The integration of Augmented Reality (AR) and Virtual Reality (VR) alongside smart manufacturing is transforming traditional industry practices by establishing a robust cyber-physical infrastructure, enhanced data visualization, and improved task execution. This thesis aims to develop AR and VR-based data visualization frameworks for the manufacturing industry, focusing on detailed implementation strategies, initial results, and key findings of these frameworks. One major focus of these frameworks is the generalization of the technological assets so that these frameworks can be …

Comparing Likert And Slider Response Formats In Clinical Assessment, Guyin Zhang

Theses and Dissertations

This study used a within-subjects experimental design to compare various response formats in fitting confirmatory factor analysis (CFA) models. Participants responded to the 8-item Center for Epidemiologic Studies Depression Scale (CES-D) across four different response formats: the Likert-type scale, three types of slider response formats, and a number-entry response format. We conducted the comparison of different response formats based on item-level scores, factor structure and psychometric properties of the scale, mean comparisons across groups, and individuals’ sum scores. Similar results were observed across the different response formats with respect to factor structure, reliability, and validity of test scores. However, inconsistent …

Electroless Deposition And Galvanic Displacement For The Control Of Supported Nanoparticle Size And Composition, Haiying Zhou

Theses and Dissertations

Catalyst performances can be greatly affected by properties such as particle size, composition, geometry, and cleanliness of the active surface. To achieve optimal catalytic performance, appropriate synthesis methods are required to synthesize the desired structures. Supported metal particle catalysts are usually prepared by impregnation and precipitation methods in industry. Although these two methods are simple, they exhibit poor control over surface morphology, leading to a wide particle size distribution and uncontrolled distribution of different metal components. In this dissertation, three topics on controlling surface morphology are discussed.

For structure sensitive reactions, reactivity and selectivity can be strongly affected by particle …

Discovering Therapeutic Strategies In Colorectal Cancer Via Synthetic Lethal Genetic Screens On Patient-Derived Organoid Models, Sana Khalili

Theses and Dissertations

Precision medicine is a revolutionary approach of targeting genetic alterations that are present only in tumor cells to find vulnerabilities that can be targeted with therapy. Identifying genetic dependencies in human colon cancer could help identify effective treatment strategies. Genome-wide CRISPR-Cas9 dropout screens can reveal all genetic dependencies, some of which could be exploited as therapeutic targets using existing drugs.

In this dissertation, I comprehensively characterized genetic dependencies present in a colon cancer organoid avatar, and validated tumor-specific selectivity of select pharmacologic agents. I identified all somatic mutations, all expressed genes, and conducted a genome-wide CRISPR dropout screen to elucidate …

Inducing And Interpreting Physical Transformation In Electroacoustic Chamber Music Via Experimental Applications Of Modular Synthesizers, Joseph Samuel Lyons

Theses and Dissertations

One of the most rapidly evolving musical genres of the 21st century is interactive electroacoustic chamber music. This is primarily due to the ongoing developments in creative technology that have increased both the idiom's technical accessibility and its potential for artistic expression. In particular, modern modular synthesizers enable electroacoustic musicians to transform the physical characteristics of sound with an extremely fine level of control. This research project has three major goals. The first goal is to explore the relationship between the many disciplines involved in this genre of music through a review of the scholarship of Aleister Crowley, Edgard Varèse, …

Real-Time Robot Pose Estimation For Industry 4.0: Enhancing Motion Validation And Monitoring With A Vision-Based Framework, Jad Samaha

Theses and Dissertations

Amidst the era of Industry 4.0, robots became integral to automated production lines by performing complex tasks with high precision and adapting to changing production needs in real-time. Therefore, ensuring their precise and reliable operation is paramount for maintaining high-quality standards and operational efficiency. This invoked the need for an automated motion validation tool that guarantees accurate program task execution, by detecting deviations or anomalies that may indicate mechanical faults or software errors. Given the exponential advancements in AI, particularly in Computer Vision, a vision-based solution is ideal for ensuring the correct positioning of a robot in real-time. Operating independently …

The Effects Of Guided Induction Completed Individually And In Groups On The Development Of Negation In Palestinian Arabic An Analysis Of Accuracy, Processing, And Rule Structure, Hana Baalousha

Theses and Dissertations

The effectiveness of different instructional interventions and the various ways such interventions promote L2 learning and processing has been the topic of recent research in the subfield of Instructed Second Language Acquisition (ISLA). Previous research on the effects of guided inductive instruction (GI) in the second language classroom has left various lacunae to be addressed, such as the effect(s) of linguistic complexity, proficiency level, modality of instruction, and the target language (Ranta, 2022). A plethora of studies in the current literature compares the efficacy of GI to deductive instruction as students work individually in computer-assisted language learning contexts (CALL) revealing …

Using Machine Learning And Deep Learning Algorithms To Improve Low Birthweight Prediction, Yang Ren

Theses and Dissertations

Low birthweight (LBW) is a major public health issue resulting in increased neonatal mortality and long-term health complications. Traditional LBW analysis methods, focusing on incidence rates and risk factors through statistical models, often struggle with complex unseen data, and thus, their effectiveness is limited in early prevention of LBW, requiring more advanced LBW prediction models. Therefore, this dissertation delves into this important research area by proposing and examining novel machine learning (ML) and deep learning (DL) algorithms, aiming to predict LBW more accurately during the early stage of pregnancy. This dissertation consists of three studies, strategically designed to build upon …

Assessing The Accuracy, Validity, And Application Of A New Method For Sex Estimation Using Isotopic Ratios Of Fe, Cu, And Zn In Human Bone, Elizabeth Anne Wakefield

Theses and Dissertations

This dissertation evaluates the accuracy, validity, and application of a novel sex determination method based on isotopic variations in copper (Cu) and iron (Fe) within human bone, initially developed by Jaouen et al. (2012). The primary aim of this research was to test the reproducibility of the method, expand the sample to include a broader age range and ethnically diverse groups, and assess its applicability in forensic contexts using contemporary skeletal samples. Bone samples were collected from 60 individuals across two curated skeletal collections: the George S. Huntington Skeletal Collection and the Texas State Forensic Anthropology Donated Skeletal Collection. The …

Creating A Quality Feedback System Between School Administrators And Teachers, Gerald Keith Price

Theses and Dissertations

After moving to a new school district as superintendent, I recognized early on that student achievement was low and intentional work needed to be done to bring about academic improvement. As the district leadership team began to explore causes and discuss possible solutions, we decided we needed to focus on changing the perception around instructional leadership. School administrators are much more likely to have mutual dialogue with their teachers when they assume the role of a coach rather than a superior. With open lines of communication, teachers and administrators are able to discuss ways to maximize learning time with students …