Digital Commons Network^™

Play, Chat, Date, Learn, And Suffer? Merton’S Law Of Unintended Consequences And Digital Technology Failures, Mark Rosenbaum, Gabby Walters, Karen Edwards J.D., Claudia Gonzalez, Germán Contreras Ramírez

Faculty Publications

No abstract provided.

Splash: Learnable Activation Functions For Improving Accuracy And Adversarial Robustness, Mohammadamin Tavakoli, Forest Agostinelli, Pierre Baldi

Publications

We introduce SPLASH units, a class of learnable activation functions shown to simultaneously improve the accuracy of deep neural networks while also improving their robustness to adversarial attacks. SPLASH units have both a simple parameterization and maintain the ability to approximate a wide range of non-linear functions. SPLASH units are: (1) continuous; (2) grounded (f(0)=0"); (3) use symmetric hinges; and (4) their hinges are placed at fixed locations which are derived from the data (i.e. no learning required). Compared to nine other learned and fixed activation functions, including ReLU and its variants, SPLASH units show superior performance across three datasets …

Seasonal Variation Of Multiple-Muon Cosmic Ray Air Showers Observed In The Nova Detector Detector On The Surface, M. A. Acero, P. Adamson, L. Aliaga, N. Anfimov, A. Antoshkin, E. Arrieta-Diaz, L. Asquith, A. Aurisano, A. Back, C. Backhouse, M. Baird, N. Balashov, P. Baldi, B. A. Bambah, S. Bashar, K. Bays, R. Bernstein, V. Bhatnagar, B. Bhuyan, J. Bian, Roberto Petti, Et. Al.

Faculty Publications

We report the rate of cosmic ray air showers with multiplicities exceeding 15 muon tracks recorded in the NOvA Far Detector between May 2016 and May 2018. The detector is located on the surface under an overburden of 3.6 meters water equivalent. We observe a seasonal dependence in the rate of multiple-muon showers, which varies in magnitude with multiplicity and zenith angle. During this period, the effective atmospheric temperature and surface pressure ranged between 210 K and 230 K and 940 mbar and 990 mbar, respectively; the shower rates are anticorrelated with the variation in the effective temperature. The variations …

Exploring How Exposure To Truth And State-Sponsored Anti-Tobacco Media Campaigns Affect Smoking Disparities Among Young Adults Using A National Longitudinal Dataset, 2002-2017, David C. Colston, Yanmei Xie, Jim Thrasher Ph.D.,Ma. Ms, Sherry Emery, Megan E. Patrick, Andrea R. Titus, Micheal R. Elliot, Nancy L. Fleischer

Faculty Publications

Background. Little is known regarding long-term impacts of anti-tobacco media campaigns on youth smoking and related disparities in the United States. Methods. We examined longitudinal cohort data from Monitoring the Future (MTF) between 2000 and 2017 in modified Poisson regression models to understand the long-term impacts of televised Truth and state-sponsored ad campaign exposure at baseline (age 18) on first cigarette and daily smoking initiation 1 to 2 years later (at modal ages 19/20). We also used additive interactions to test for potential effect modification between campaign exposure and smoking outcomes by sex, race/ethnicity, and parental educational attainment. Results. We …

Spoken Word Learning In Children With Developmental Language Disorder Or Dyslexia, Suzanne M. Adlof, Lauren S. Baron, Bethany A. Bell, Joanna Scoggins

Faculty Publications

Purpose Word learning difficulties have been documented in multiple studies involving children with dyslexia and developmental language disorder (DLD; see also specific language impairment). However, no previous studies have directly contrasted word learning in these two frequently co-occurring disorders. We examined word learning in second-grade students with DLD-only and dyslexia-only as compared to each other, peers with both disorders (DLD + dyslexia), and peers with typical development. We hypothesized that children with dyslexia-only and DLD-only would show differences in word learning due to differences in their core language strengths and weaknesses. Method Children ( = 244) were taught eight novel …

Medication Adherence Reminder System For Virtual Home Assistants: Mixed Methods Evaluation Study, Cythnia F. Corbett, Elizabeth M. Combs, Peyton S. Chandarana, Isabel Stringfellow, Karen Worthy, Thien Nguyen, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Jason M. O'Kane

Faculty Publications

Background: Medication nonadherence is a global public health challenge that results in suboptimal health outcomes and increases health care costs. Forgetting to take medicines is one of the most common reasons for unintentional medication nonadherence. Research findings indicate that voice-activated virtual home assistants, such as Amazon Echo and Google Home devices, may be useful in promoting medication adherence.

Objective: This study aims to create a medication adherence app (skill), MedBuddy, for Amazon Echo devices and measure the use, usability, and usefulness of this medication-taking reminder skill.

Methods: A single-group, mixed methods, cohort feasibility study was conducted with women who took …

Andrographolide Attenuates Gut-Brain-Axis Associated Pathology In Gulf War Illness By Modulating Bacteriome-Virome Associated Inflammation And Microglia-Neuron Proinflammatory Crosstalk, Punnag Saha, Peter T. Skidmore, Larinda A. Holland, Ayan Mondal, Dipro Bose, Ratanesh K. Seth, Kimberly Sullivan, Patricia A. Janulewicz, Ronnie Horner, Nancy Klimas, Mitzi Nagarkatti, Prakash Nagarkatti, Efrem S. Lim, Saurabh Chatterjee

Faculty Publications

Gulf War Illness (GWI) is a chronic multi-symptomatic illness that is associated with fatigue, pain, cognitive deficits, and gastrointestinal disturbances and presents a significant challenge to treat in clinics. Our previous studies show a role of an altered Gut-Brain axis pathology in disease development and symptom persistence in GWI. The present study utilizes a mouse model of GWI to study the role of a labdane diterpenoid andrographolide (AG) to attenuate the Gut-Brain axis-linked pathology. Results showed that AG treatment in mice (100 mg/kg) via oral gavage restored bacteriome alterations, significantly increased probiotic bacteria , , and , the genera that …

High-Throughput Computation Of New Carbon Allotropes With Diverse Hybridization And Ultrahigh Hardness, Mohammed Al-Fahdi, Alejandro Rodriguez, Tao Ouyang, Ming Hu

Faculty Publications

The discovery of new carbon allotropes with different building blocks and crystal symmetries has long been of great interest to broad materials science fields. Herein, we report several hundred new carbon allotropes predicted by the state-of-the-art RG² code and first-principles calculations. The types of new carbon allotropes that were identified in this work span pure sp² , hybrid sp²/sp³ , and pure sp³ C–C bonding. All structures were globally optimized at the first-principles level. The thermodynamic stability of some selected carbon allotropes was further validated by computing their phonon dispersions. The predicted carbon allotropes …

A Practical Approach For The Applied Voice Instructor Utilizing Limited Piano Skills In The Studio Setting, Lee Whittington Ousley

Theses and Dissertations

Providing a process for reducing accompaniments to commonly assigned undergraduate vocal repertoire could aid instructors with limited piano skills in the applied studio setting. Through the use of questionnaires and an online survey, it was determined that there is a population of undergraduate instructors of voice that do not have an accompanist present to play during student lessons. Without an accompanist, many teachers are unable to play the pieces as written, which warrants the creation of reduced scores as useful alternatives to pre-recorded tracks.

An online survey was distributed to determine if the population of teachers was significant enough to …

Bankruptcy, Taxes, And The Primacy Of Irs Refund Offsets: Copley V. United States, Michelle Lyon Drumbl

South Carolina Law Review

No abstract provided.

Making Executioners Out Of Pharmacists: Why South Carolina Should Not Adopt A Lethal Injection Secrecy Statute, Elizabeth T. French

South Carolina Law Review

No abstract provided.

A Legacy Of Slavery: The Citizen's Arrest Laws Of Georgia And South Carolina, Roger M. Stevens

South Carolina Law Review

No abstract provided.

Covid-19 And Business Interruption Insurance: The Constitutionality Of Legislatively Mandated Coverage, William G. Arnold

South Carolina Law Review

No abstract provided.

Regulation Of Inflammatory Processes By Tryptamine, Cannabidiol And 2,3,7,8-Tetrachlorodibenzo-P-Dioxin, Nicholas Dopkins

Theses and Dissertations

Host immunity is a complicated system of pro-inflammatory and anti-inflammatory processes that respond to exogenous and endogenous threats to regulate host physiology, inhibit carcinogenesis, and protect from infections. Sustained deviance from normal immunological function occurs due to a variety of factors both endogenous and exogenous, with some factors that can dysregulate host immunity including: genetics, microbiota composition, toxin exposure, age, gender, and smoking. The etiology of inflammatory disorders is both convoluted and complex due to the sheer number of facets regulating host immunity. To better contribute to understanding how immunological dysregulation occurs we focused on how three anti-inflammatory compounds (tryptamine, …

John Laurens: An Artist Rediscovered In The Ethelind Pope Brown Collection, Nicole Alexandra Gerth

Theses and Dissertations

The Ethelind Pope Brown collection at the Irvin Department of Rare Books & Special Collections at the University of South Carolina contains thirty-two gouache paintings of south-eastern North American flora and fauna from the eighteenth century. Colonel John Laurens, a native South Carolinian from the eighteenth century, is the decided artist for the collection after appraisers and scholars confirmed that the works were painted by a local amateur artist. Historians respect Laurens for his abolitionist ideologies and his status as an officer under George Washington’s service, but his accomplishment as an amateur naturalist artist is not as well documented. From …

A Descriptive Study About Instructor And Student Attitudes Towards The Use Of Educational Technology In Nursing Instruction, David Lawrence Stanghellini

Theses and Dissertations

In recent years, concern has been expressed by the Institute of Medicine (IOM) and the National League for Nursing (NLN) that nursing school graduates lack critical thinking skills needed to provide increasingly complex care to today’s hospitalized patient. Although the use of educational technology in the classroom has been associated with improved critical thinking and performance, some instructors at schools of nursing remain reluctant to integrating technology into their pedagogy. Barriers to technology integration include limited knowledge in the use of technology, perceived low self-efficacy, concerns about training, and long-term support.

This study examined factors that affect instructor and student …

An Analysis Of Mental State Verbs In Children With Hearing Loss, Morgan Vachio

Theses and Dissertations

Mental state verbs (MSV) require unique cognitive and linguistic knowledge compared to lower level function words (Shatz et al., 1983). These cognitive and linguistic demands are thought to be difficult for children with hearing loss (CHL) due to deficits in word learning (Werfel, 2017; Lund, 2016), limited depth of vocabulary knowledge (Walker et al., 2018) and deficits in complex syntax (Werfel et al., 2021). The present study recruited 73 preschool children (23 CHLCI, 22 CHL-HA and 28 CNH) to participate. Our analysis examined the frequency, lexical diversity and use of MSV within required complex syntax structures.

The Effects Of A Dialogic Pedagogy In A Hybrid Advanced Placement Environmental Science Course On Students’ Learning Experience, Blake Alspach

Theses and Dissertations

This action research study evolved from the sudden shift in schools and districts in response to the COVID 19 pandemic. Shifting from a traditional face-to-face AP Environmental Science classroom to a hybrid classroom required evaluating and revising the pedagogical choices made to create a positive learning experience. A hybrid classroom consists of face-to-face students in the classroom and online students attending the class simultaneously through video conferencing software. Teachers and students had little to no experience engaging in a hybrid learning model, thus creating a need to develop and implement effective instructional practices to support student learning. This qualitative action …

Race Is Not A Risk Factor: Examining The Influence Of Models Of Care, Race, And Discrimination On Racial Disparities In Maternal Outcomes, Curisa Mae Tucker

Theses and Dissertations

Maternal health outcomes are worst for racial and ethnic minority patients in the United States. There are disparities in pregnancy-related death and severe maternal morbidities where Black women suffer the most disparate outcomes. However, much of the previous scholarly work in this arena has charged that race is a risk factor for adverse maternal outcomes in which this dissertation refutes.

To better understand this phenomenon, we first conducted a scoping review of literature. Our aim was to examine the current state of literature on group prenatal care and its impact on maternal outcomes and racial disparities in adverse maternal outcomes. …

Perspective: The Importance Of Water Security For Ensuring Food Security, Good Nutrition, And Well-Being, Sera L. Young, Edward A. Frongillo Jr., Zeina Jamaluddine, Hugo Melgar-Quiñonez, Rafael Pérez-Escamilla, Claudia Ringler, Asher Y. Rosinger

Faculty Publications

Water security is a powerful concept that is still in its early days in the field of nutrition. Given the prevalence and severity of water issues and the many interconnections between water and nutrition, we argue that water security deserves attention commensurate with its importance to human nutrition and health. To this end, we first give a brief introduction to water insecurity and discuss its conceptualization in terms of availability, access, use, and stability. We then lay out the empirical grounding for its assessment. Parallels to the food-security literature are drawn throughout, both because the concepts are analogous and food …

Rabies Postexposure Prophylaxis In The United States: Opportunities To Improve Access, Coordination, And Delivery, Gavin T. Howington, Huy-Binh Nguyen, P Brandon Bookstaver, Peter Akpunonu, Joshua T. Swan

Faculty Publications

No abstract provided.

Deference Is Dead, Long Live Chevron, Nathan D. Richardson

Faculty Publications

Chevron v. NRDC has stood for more than 35 years as the central case on judicial review of administrative agencies’ interpretations of statutes. Its contours have long been debated, but more recently it has come under increasing scrutiny, with some—including two sitting Supreme Court Justices—calling for the case to be overturned. Others praise Chevron, calling deference necessary or even inevitable. All seem to agree the doctrine is powerful and important.

This standard account is wrong, however. Chevron is not the influential doctrine it once was and has not been for a long time. It has been eroded from the outside …

Preventing The Preventable: A Review Of Maternal Mortality Rates In South Carolina, Sydney J. Douglas

South Carolina Law Review

No abstract provided.

The District Of South Carolina's Approach To Post-Removal Damage Stipulations: The Need For One Less "Controversy" In The Amount-In-Controversy Analysis, Samuel C. Williams

South Carolina Law Review

No abstract provided.

Judges As Superheroes: The Danger Of Confusing Constitutional Decisions With Cosmic Battles, H. Jefferson Powell

South Carolina Law Review

No abstract provided.

Investigating The Influence Of Mentors With National Board Certification On Mentees’ Perceptions Of Their Own Teaching Practice And Attitudes Of Remaining A Teacher, Joshua Michael Mcgoun

Theses and Dissertations

In Maryland, 47% of new teachers do not see a third year of teaching. Maryland also imports more teachers from neighboring states than it produces on its own (Kirwan & Hise, 2020). In order to improve new teachers’ skills and hopefully retain them, The Maryland Commission on Innovation and Excellence has proposed creating the position of “Master Teacher” to mentor new teachers. The “Master Teachers” need to earn National Board Certification (NBC) to be considered for the position. This research study examined mentees’ reflections and analyzed the presence of themes relating to the National Board for Professional Teaching Standards’ Five …

A Comparison Of Spatial Clustering Assessment Methods, Nadeesha Dilhani Vidanapathirana

Theses and Dissertations

Spatial clustering detection methods are widely used in many fields of research including sociology, epidemiology, ecology, and criminology. The objective of this study is to assess the performance of four spatial clustering detection methods: the average nearest neighbor ratio, Ripley’s K function, local Moran’s I and Getis-Ord Gi* statistics. We conduct a simulation study to evaluate the performance of each method for areal data under different types of spatial dependence and three different areal structures; a 20x20 regular grid, United States counties in six states and Canadian forward sortation areas (FSAs) in three provinces. The results shows that the empirical …

Partitioning Of Volatile Organic Compounds Into The Multiple Environmental Compartments, Jeonghyeon Ahn

Theses and Dissertations

Volatile organic compounds (VOCs) dominate the class of pollutants that accumulate in the atmosphere and indoors. Partitioning coefficient is a measure of a compound’s ability to distribute between two phases. Assessing the partitioning of VOCs is essential to determine their transport, fate, behavior, and adverse environmental and health impacts across multiple environmental compartments. Studies on VOC partitioning have been limited because discriminating the small mass fraction of VOCs in aerosol particles is difficult to quantify. The partitioning of VOCs into soil, air, and aerosol particle phases was investigated under dynamic laboratory conditions. A bench-scale system that precisely controlled the relative …

Accurate And Integrative Detection Of Copy Number Variants With High-Throughput Data, Xizhi Luo

Theses and Dissertations

Copy number variation, as a major source of genetic variation in the human genome, are gains or losses of the DNA segments. Copy number variation has gained considerable interest as it plays important roles in human complex diseases. Therefore, accurate detection of CNVs with data generated by modern genotyping technologies, such as SNP array and whole-exome sequencing (WES), comprises a critical step toward a better understanding of disease etiology. However, current statistical methodologies for CNV detection still face analytical challenges due to numerous genetic and technological factors that may lead to spurious findings. First, existing methods assume the independent observations …

Dysbiosis-Related Medications And The Association With Cognitive Decline, Cognitive Impairment, And Dementia, Nicholas Victor Resciniti

Theses and Dissertations

The main objectives of this dissertation were to quantitatively assess whether there is an association between medications (e.g., antibiotics, PPIs, antipsychotics) and cognitive performance over time, conduct a causal mediation analysis to evaluate the role of inflammation (C-reactive protein) in the association between medications and subsequent cognitive decline, and examine if dysbiosis-related medications (DRM) are associated with a greater risk of dementia for participants that were cognitively normal and had MCI at baseline.

The Health and Retirement Study (HRS) was used to conduct a secondary data analysis that used longitudinal data from 2004 to 2016. The HRS is an ongoing, …