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Articles 11401 - 11430 of 11798
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Holocene Sea-Level Changes Along The Channel Coast Of South-West England, Anthony Carl Massey
Holocene Sea-Level Changes Along The Channel Coast Of South-West England, Anthony Carl Massey
School of Geography, Earth and Environmental Sciences Theses
A Holocene relative sea-level (RSL) history for the south Devon coast is reconstructed through an analysis of twelve cores extracted from the coastal back-barrier environments of Bantham Sands, North Sands, Slapton Sands and Blackpool Sands. Foraminifera preserved in the sediments are assigned an indicative meaning based on the vertical distribution of their modem counterparts from contemporary salt marsh and mudflat environments in the Erme and Salcombe-Kingsbridge estuaries. The contemporary data provide the first inter-tidal (-2.6 to +2.6 m MTL) foraminifera-based transfer function for south-west England from which sea-level changes can be predicted with good precision (RMSEP = ±0.29 m). Sea-level …
Particulate Phytochelatins As An Indication Of Metal Stress In Natural Waters, Silvia Keiko Kawakami
Particulate Phytochelatins As An Indication Of Metal Stress In Natural Waters, Silvia Keiko Kawakami
School of Geography, Earth and Environmental Sciences Theses
The aim of this study was to investigate the metal stress response of phytoplankton in the Fal, Plym and Tamar Estuaries (SW England, UK) by field measurements of particulate phytochelatins (PCs) and glutathione (GSH) and their relationships with Cu speciation. A high performance liquid chromatographic method was optimised for the determination of particulate PCs and GSH from estuarine waters. Dissolved Cu speciation was determined using well established cathodic stripping voltammetric methods. Glutathione was found throughout the estuaries ranging from 0.6 to 274 µmol (g chl α)ˉ¹ , and PCs were detected mostly in the Fal samples at concentrations up to …
Visualization Techniques For The Analysis Of Neurophysiological Data, Martin Alan Walter
Visualization Techniques For The Analysis Of Neurophysiological Data, Martin Alan Walter
School of Engineering, Computing and Mathematics Theses
In order to understand the diverse and complex functions of the Human brain, the temporal relationships of vast quantities of multi-dimensional spike train data must be analysed. A number of statistical methods already exist to analyse these relationships. However, as a result of expansions in recording capability hundreds of spike trains must now be analysed simultaneously. In addition to the requirements for new statistical analysis methods, the need for more efficient data representation is paramount. The computer science field of Information Visualization is specifically aimed at producing effective representations of large and complex datasets. This thesis is based on the …
Multiple Experts: Scientific, Medical, Media And Lay Discourses On 'New Genetics', Clare Elizabeth Wilkinson
Multiple Experts: Scientific, Medical, Media And Lay Discourses On 'New Genetics', Clare Elizabeth Wilkinson
Other Faculty of Health Theses
The significance of public relationships with scientific and medical expertise has increasingly been highlighted as an area of importance in governmental policy formulation and scientific activities. Central to this relationship has been the role of the media, frequently depicted as increasing the strained communications between science, medicine and the public in the present UK 'crisis' of expertise. Sociological research has contributed to our understandings of science, medicine, the media and lay knowledge. The research presented in this thesis correlates these contributions. It focuses on 'new genetics' to elicit the views towards communication and understanding expressed by three groups; media professionals, …
Matching Provision To Needs : The Example Of Victim Support, Lesley Simmonds
Matching Provision To Needs : The Example Of Victim Support, Lesley Simmonds
Other Faculty of Arts, Humanities and Business Theses
The current study is an evaluation of a voluntary sector service, Victim Support. The focal points of this work are the impact of crime upon victims and the extent to which they feel that Victim Support, as a service provider, has helped to restore their sense of equilibrium. In this way the success of a community response to crime is considered. The research was undertaken between 1998 and 2002 and was largely based upon the work of one local scheme; Victim Support, Plymouth. The study included the views of service users (victims of crime) and those of service providers (paid …
Dynamic Magnetic Effects In Amorphous Microwires For Sensors And Coding Applications, Serghei Sandacci
Dynamic Magnetic Effects In Amorphous Microwires For Sensors And Coding Applications, Serghei Sandacci
School of Engineering, Computing and Mathematics Theses
This work is devoted to the study of the dynamic properties of magnetic amorphous wires, in particular, glass-coated microwires, which have small diameters (5-30 microns), outstanding soft magnetic behaviour with a high permeability and low coercivity, yet, possess a well-defined magnetic structure. First part of my PhD research has been devoted to the investigation of a bi-stable magnetisation reversal in glass-coated amorphous microwires. In contrast to traditional approaches, where characteristics of the magnetisation reversal are analysed as a consequence of the eddy current effect, l have applied stochastic methods for modelling the remagnetisation reversal in the microwires with axial anisotropy. …
User Authentication And Supervision In Networked Systems, Paul Steven Dowland
User Authentication And Supervision In Networked Systems, Paul Steven Dowland
School of Engineering, Computing and Mathematics Theses
This thesis considers the problem of user authentication and supervision in networked systems. The issue of user authentication is one of on-going concern in modem IT systems with the increased use of computer systems to store and provide access to sensitive information resources. While the traditional username/password login combination can be used to protect access to resources (when used appropriately), users often compromise the security that these methods can provide. While alternative (and often more secure) systems are available, these alternatives usually require expensive hardware to be purchased and integrated into IT systems. Even if alternatives are available (and financially …
Early Detection Of Dementia Using The Human Electroencephalogram, Geoffrey T Henderson
Early Detection Of Dementia Using The Human Electroencephalogram, Geoffrey T Henderson
School of Engineering, Computing and Mathematics Theses
Improved life expectancy has led to a significant increase in the number of people in the high-riskage groups that will develop Alzheimer's disease and other dementia. Efforts are being made to develop treatments that slow the progress of these diseases. However, unless a sufferer is diagnosed in the early stages the treatments cannot give the maximum benefit. Therefore, there isan urgent need for a practical, decision support tool that will enable the earliest possible detectionof dementia within the large at-risk population.Current techniques such as Magnetic Resonance Imaging (MRI) that are used to diagnose andassess neurological disorders require specialist equipment and …
The Ecological Causes And Consequences Of Prey Choice And Ontogenetic Niche Shifts In The Common Goby, Angus Charles Jackson
The Ecological Causes And Consequences Of Prey Choice And Ontogenetic Niche Shifts In The Common Goby, Angus Charles Jackson
School of Biological and Marine Sciences Theses
Foraging behaviour of the common goby, Pomatoschistus microps was investigated in both the United Kingdom and Sweden, with the aim of establishing causes and consequences of prey choice and ontogenetic shifts in diet. Goby life-cycle could be clearly divided into two stages, where prey choice changed abruptly from meio- to macrofauna at a standard length of 30 mm. This diet-shift maximised net energy intake rates, as illustrated by a quantitatively validated optimal foraging model. Intrinsic mechanisms were of greater importance than extrinsic factors in driving this shift. Metabolism, the primary prey choice determinant, revealed canalised and predictable diet shifts in …
Ecology And Conservation Of Mediterranean Temporary Ponds In The Uk, Louise Mcabendroth
Ecology And Conservation Of Mediterranean Temporary Ponds In The Uk, Louise Mcabendroth
School of Biological and Marine Sciences Theses
Macroinvertebrate and plant assemblage composition and abiotic habitat characteristics were examined in seventy-six ponds, in the New Forest (Hampshire, UK) and on the Lizard Peninsula (Cornwall, UK), in order to unravel the ecological processes influencing ponds at a range of spatial scales and provide a clear definition of Mediterranean Temporary Pond (MTP) habitat (92/43/EEC) in the UK. In addition, a set of newly created experimental ponds were monitored on the Lizard to examine patterns of colonisation and evaluate the use of habitat creation in temporary pond conservation. The findings are synthesised into a number of management recommendations for ponds in …
Factors Influencing The Accuracy Of Task Completion Time Estimates, Kevin Edward Thomas
Factors Influencing The Accuracy Of Task Completion Time Estimates, Kevin Edward Thomas
School of Psychology Theses
Whilst considerable research has found that people tend to underestimate their task completion times (e.g., Buehler et al., 1994), factors that might influence the accuracy of temporal predictions have received little empirical treatment. The research presented in this thesis identified two distinct factors that mediated time estimation accuracy and bias. One factor was task duration, whereas the other factor was the person’s prior experience of the task. There was evidence that having prior experience of performing all or a substantial part of the same task enabled participants to more accurately estimate its duration. Additionally, predictions were more accurate when participants …
Ecology And Conservation Of Mediterranean Temporary Ponds In The Uk, Louise Mcabendroth
Ecology And Conservation Of Mediterranean Temporary Ponds In The Uk, Louise Mcabendroth
School of Biological and Marine Sciences Theses
Macroinvertebrate and plant assemblage composition and abiotic habitat characteristics were examined in seventy-six ponds, in the New Forest (Hampshire. UK) and on the Lizard Peninsula (Cornwall, UK), in order to unravel the ecological processes influencing ponds at a range of spatial scales and provide a clear definition of Mediterranean Temporary Pond (MTP) habitat (92/43/EEC)in the UK. In addition, a set of newly created experimental ponds were monitored on the Lizard to examine patterns of colonisation and evaluate the use of habitat creation in temporary pond conservation. The findings are synthesised into a number of management recommendations for ponds in the …
Studies On Myxozoan Parasites Of Freshwater Fish And Invertebrate Hosts, Matthew Longshaw
Studies On Myxozoan Parasites Of Freshwater Fish And Invertebrate Hosts, Matthew Longshaw
School of Biological and Marine Sciences Theses
A study of myxozoan parasites has been investigated in hosts from freshwater environments in the UK. Over 17,000 oligochaetes, almost 5,000 juvenile cyprinids representing 7 species and over 60 invertebrate species have been examined for the presence of myxozoan parasites. In addition, studies on the lifecycle of Tetracapsuloides bryosalmonae (the causative agent of salmonid proliferative kidney disease, PKD) and of selected cyprinid myxozoans were conducted. A total of 21 actinospore types in seven collective groups were isolated and described from oligochaetes collected from seven different river systems in England and Wales. Twelve of the actinospores isolated appear to be new …
Deconstructing The Tower Of London : Resolution, Alternatives And Executive Function, Hassina Carder-Gilbert
Deconstructing The Tower Of London : Resolution, Alternatives And Executive Function, Hassina Carder-Gilbert
School of Psychology Theses
Although widely employed as an executive task, the performance demands of the Tower of London task (TOL) are not well understood. The aim of this Thesis is to determine what TOL measures and seven studies are included that illustrate its performance demands. Much of the work is experimental and TOL is explored via a novel verification paradigm in which participants make speeded judgements about whether a demonstrated move is optimal or suboptimal. The deconstruction of the task to the level of the individual move indicated that the number of moves until a disk was placed in its goal position (resolution) …
Supplementary Prescribing By Pharmacists: A New Opportunity?, Gj Sewell
Supplementary Prescribing By Pharmacists: A New Opportunity?, Gj Sewell
School of Health Professions
No abstract provided.
Responsibility, Accountability And Factors Influencing Provision Of Pharmacist Transcription Of Discharge Prescriptions, Gj Sewell, Rj Hobson
Responsibility, Accountability And Factors Influencing Provision Of Pharmacist Transcription Of Discharge Prescriptions, Gj Sewell, Rj Hobson
School of Health Professions
No abstract provided.
An Unsupervised Kernel Based Fuzzy C-Means Clustering Algorithm With Kernel Normalisation, S-M Zhou, Jq Gan
An Unsupervised Kernel Based Fuzzy C-Means Clustering Algorithm With Kernel Normalisation, S-M Zhou, Jq Gan
School of Nursing and Midwifery
In this paper, a novel procedure for normalising Mercer kernel is suggested firstly. Then, the normalised Mercer kernel techniques are applied to the fuzzy c-means (FCM) algorithm, which leads to a normalised kernel based FCM (NKFCM) clustering algorithm. In the NKFCM algorithm, implicit assumptions about the shapes of clusters in the FCM algorithm is removed so that the new algorithm possesses strong adaptability to cluster structures within data samples. Moreover, a new method for calculating the prototypes of clusters in input space is also proposed, which is essential for data clustering applications. Experimental results on several benchmark datasets have demonstrated …
Krox-20 Inhibits Jun-Nh2-Terminal Kinase/C-Jun To Control Schwann Cell Proliferation And Death, David B. Parkinson, Ambily Bhaskaran, Sarah Dickinson, Anna Droggiti
Krox-20 Inhibits Jun-Nh2-Terminal Kinase/C-Jun To Control Schwann Cell Proliferation And Death, David B. Parkinson, Ambily Bhaskaran, Sarah Dickinson, Anna Droggiti
Peninsula Medical School
No abstract provided.
Gats Impacts On Entry Modes And Defensive Marketing Strategies In The Egyptian Banking Sector, Mansour Salman Mohamad Abdel-Maguid Lotayif
Gats Impacts On Entry Modes And Defensive Marketing Strategies In The Egyptian Banking Sector, Mansour Salman Mohamad Abdel-Maguid Lotayif
Plymouth Business School Theses
This research examines the effects of GATS agreements, both on entry modes and defensive marketing strategies in the Egyptian banking sector. The research population is the Egyptian banking sector, employing a total of 83179, from which a representative sample (equal to 800 responses) was selected. As the research aims are diversified, this sample was divided into two main groups i.e. local banks and foreign branches, investigated using different questionnaires. The latter population includes all the foreign branches working in the Egyptian market; the former includes all banks working in Egypt regardless of their ownership status. Four objectives have been pursued …
Stroke In Devon: Knowledge Was Good, But Action Was Poor., C. Carroll, J. Hobart, C. Fox, L. Teare, J. Gibson
Stroke In Devon: Knowledge Was Good, But Action Was Poor., C. Carroll, J. Hobart, C. Fox, L. Teare, J. Gibson
Peninsula Medical School
BACKGROUND AND AIM: Effective implementation of early treatment strategies for stroke requires prompt admission to hospital. There are several reasons for delayed admission. Good awareness should facilitate early admission. We identified local targets for education. METHODS: Four groups, each of 40 people, completed questionnaires to determine their knowledge of stroke symptoms and risk factors, and the action they took or would take in the event of a stroke. The groups were: patients with a diagnosis of stroke or TIA (within 48 hrs of admission); patients at risk of stroke; the general population; and nurses. RESULTS: Forty per cent of stroke …
Raised Intracranial Pressure Presenting With Spontaneous Periorbital Bruising: Two Case Reports, S Hadjikoutis, Cb Carroll, Gtp Plant
Raised Intracranial Pressure Presenting With Spontaneous Periorbital Bruising: Two Case Reports, S Hadjikoutis, Cb Carroll, Gtp Plant
Peninsula Medical School
The venous drainage of the orbit is known to be via the ophthalmic and vortex veins which communicate with the cavernous sinus. We describe two patients with raised intracranial pressure presenting with periorbital bruising. In one patient dural venous sinus thrombosis was demonstrated and it is suspected that the cause of the raised intracranial pressure may have been the same in the second. We suggest that the abrupt rise of pressure in the cerebral venous system was transmitted via the cavernous sinus to the orbital venous system.
Provision Of 24 Hour Acute Neurology Care By Neurologists: Manpower Requirements In The Uk., C. Carroll, J. Zajicek
Provision Of 24 Hour Acute Neurology Care By Neurologists: Manpower Requirements In The Uk., C. Carroll, J. Zajicek
Peninsula Medical School
OBJECTIVES: The ABN has published standards of care for patients with acute neurological disease. Derriford Hospital provides a 24 hour neurology intake service to a population of 500,000 with the equivalent of four consultants, three specialist registrars (SpRs), and four senior house officers (SHOs) with a 37 bed ward. The authors undertook a prospective study of all neurology admissions to enable calculation of manpower necessary to meet the ABN guidelines. METHODS: All admissions to the neurology department were analysed prospectively for a three month period (March to May 2002). RESULTS: There were 629 admissions (equating to 2500 per year); data …
A Randomised Controlled Trial And Cost Effectiveness Study Of Systematic Screening (Targeted And Total Population Screening) Versus Routine Practice For The Detection Of Atrial Fibrillation In The Over 65s: (Safe) [Isrctn19633732], Dawn Swancutt, Richard Hobbs, David Fitzmaurice, Jonathan Mant, Ellen Murray, Sue Jowett, James Raftery, Stirling Bryan, Michael Davies, Gregory Lip
A Randomised Controlled Trial And Cost Effectiveness Study Of Systematic Screening (Targeted And Total Population Screening) Versus Routine Practice For The Detection Of Atrial Fibrillation In The Over 65s: (Safe) [Isrctn19633732], Dawn Swancutt, Richard Hobbs, David Fitzmaurice, Jonathan Mant, Ellen Murray, Sue Jowett, James Raftery, Stirling Bryan, Michael Davies, Gregory Lip
Peninsula Medical School
Background Atrial fibrillation (AF) has been recognised as an important independent risk factor for thromboembolic disease, particularly stroke for which it provides a five-fold increase in risk. This study aimed to determine the baseline prevalence and the incidence of AF based on a variety of screening strategies and in doing so to evaluate the incremental cost-effectiveness of different screening strategies, including targeted or whole population screening, compared with routine clinical practice, for detection of AF in people aged 65 and over. The value of clinical assessment and echocardiography as additional methods of risk stratification for thromboembolic disease in patients with …
Small-Scale Distribution Of Juvenile Gadoids In Shallow Inshore Waters; What Role Does Maerl Play?, Na Kamenos, Pg Moore, Jm Hall-Spencer
Small-Scale Distribution Of Juvenile Gadoids In Shallow Inshore Waters; What Role Does Maerl Play?, Na Kamenos, Pg Moore, Jm Hall-Spencer
School of Biological and Marine Sciences
No abstract provided.
Doctoral Thesis Proposal Defence Seminar., Tj Lynch
Doctoral Thesis Proposal Defence Seminar., Tj Lynch
Plymouth Institute of Education
Lynch, T. (2003, November 3). Evaluating the implementation of the new Queensland health and physical education documents (1999) in Brisbane Catholic Education primary schools.
Functional Interaction Between The Bloom's Syndrome Helicase And The Rad51 Paralog, Rad51l3 (Rad51d), Jp Braybrooke, J-L Li, L Wu, Et Al
Functional Interaction Between The Bloom's Syndrome Helicase And The Rad51 Paralog, Rad51l3 (Rad51d), Jp Braybrooke, J-L Li, L Wu, Et Al
School of Biomedical Sciences
Bloom's syndrome (BS) is a genetic disorder associated with short stature, fertility defects, and a predisposition to the development of cancer. BS cells are characterized by genomic instability; in particular, a high rate of reciprocal exchanges between sister-chromatids and homologous chromosomes. The BS gene product, BLM, is a helicase belonging to the highly conserved RecQ family. BLM is known to form a complex with the RAD51 recombinase, and to act upon DNA intermediates that form during homologous recombination, including D-loops and Holliday junctions. Here, we show that BLM also makes a direct physical association with the RAD51L3 protein (also known …
An Economic Anaysis Of The Impact Of Eu Accession Upon Crude Oil And Oil Production Policy In Lithuania, Irma Pasukeviciute
An Economic Anaysis Of The Impact Of Eu Accession Upon Crude Oil And Oil Production Policy In Lithuania, Irma Pasukeviciute
School of Biological and Marine Sciences Theses
This thesis presents a two-stage economic and policy analysis of the impact of European Union (EU) accession upon crude oil production and transportation policy in Lithuania. The first stage provides the theoretical framework for the research. The analysis begins with the overview of the Russian oil industry, as for over 50 years Lithuania was part of the Soviet Union and thus its oil industry was largely controlled by Russian interests. Although Lithuania became independent in 1991, the dependency on Russia in terms of energy remains until today. The following chapters introduce Lithuania's development since its independence, outline the relationship with …
A Computer Aided Detection System For Mammographic Images Implemented On A Grid Infrastructure, U Bottigli, P Cerello, P Delogu, Me Fantacci, Et Al
A Computer Aided Detection System For Mammographic Images Implemented On A Grid Infrastructure, U Bottigli, P Cerello, P Delogu, Me Fantacci, Et Al
School of Engineering, Computing and Mathematics
The use of an automatic system for the analysis of mammographic images has proven to be very useful to radiologists in the investigation of breast cancer, especially in the framework of mammographic-screening programs. A breast neoplasia is often marked by the presence of microcalcification clusters and massive lesions in the mammogram: hence the need for tools able to recognize such lesions at an early stage. In the framework of the GPCALMA (GRID Platform for Computer Assisted Library for MAmmography) project, the co-working of italian physicists and radiologists built a large distributed database of digitized mammographic images (about 5500 images corresponding …
Proapoptotic Genes Bax And Cd40l Are Predictors Of Survival In Transitional Cell Carcinoma Of The Bladder, Sa Hussain, R Ganesan, L Hiller, Pg Murray, Et Al
Proapoptotic Genes Bax And Cd40l Are Predictors Of Survival In Transitional Cell Carcinoma Of The Bladder, Sa Hussain, R Ganesan, L Hiller, Pg Murray, Et Al
Peninsula Medical School
The purpose of the study was to investigate the effects of expression of a range of genes involved in apoptosis on outcome in bladder cancer. Immunohistochemistry was used to examine expression of BCL2, BAX, P53, CD40 and CD40L in archival tissues of patients included in various treatment trials for transitional cell carcinoma (TCC) of the bladder. Data were collected on 94 patients who first presented with either invasive or superficial bladder cancer. Median follow-up for alive patients was 83 months (m) (range 12-195 m). Median survival was 80 m (95% CI=56-128 m). Median survivals for the various markers were as …
Individual Differences And Strategies For Human Reasoning, Alison Bacon
Individual Differences And Strategies For Human Reasoning, Alison Bacon
School of Psychology Theses
Theories of human reasoning have tended to assume cognitive universality, i. e. that all individuals reason in basically the same way. However, some research (e. g. that of Ford. 1995) has found evidence of individual differences in the strategies people use for syllogistic reasoning. This thesis presents a series of experiments which aimed to identify individual differences in strategies for human reasoning and investigate their nature and aetiology. Experiment 1 successfully replicated and extended Ford (1995) and provided further evidence that most individuals prefer to reason with either verbal-propositional or visuo-spatial representations. Data from verbal and written protocols showed that …