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A Sequential Temperature Cycling Study For The Investigation Of Carboplatin Infusion Stability To Facilitate Dose-Banding, Gj Sewell, S Kaestner Jan 2007

A Sequential Temperature Cycling Study For The Investigation Of Carboplatin Infusion Stability To Facilitate Dose-Banding, Gj Sewell, S Kaestner

School of Health Professions

No abstract provided.


Chemotherapy Dosing Part I: Scientific Basis For Current Practice And Use Of Body Surface Area, Gj Sewell, S Kaestner Jan 2007

Chemotherapy Dosing Part I: Scientific Basis For Current Practice And Use Of Body Surface Area, Gj Sewell, S Kaestner

School of Health Professions

No abstract provided.


Chemotherapy Dosing Part Ii: Alternative Approaches And Future Prospects, Gj Sewell, S Kaestner Jan 2007

Chemotherapy Dosing Part Ii: Alternative Approaches And Future Prospects, Gj Sewell, S Kaestner

School of Health Professions

No abstract provided.


Custom-Made Total Contact Insoles And Prefabricated Functional Diabetic Insoles: A Case Report, J Paton, E Stenhouse, R Jones, G Bruce Jan 2007

Custom-Made Total Contact Insoles And Prefabricated Functional Diabetic Insoles: A Case Report, J Paton, E Stenhouse, R Jones, G Bruce

School of Health Professions

Insoles are commonly prescribed to offload the mechanical stresstransmitted to the plantar tissues of the foot. Traditionally, thecustom-made total-contact insole (TCI) is favoured over itsprefabricated counterpart. The introduction of a new prefabricateddiabetic insole (A Algeo Ltd, Liverpool) designed to modify footbiomechanics may offer an instant, low-cost, clinically-effectivealternative. We report on a comparison of the two insoles in thecase of a 54-year-old woman with type 2 diabetes and peripheralneuropathy, presenting with ulceration overlying the thirdmetatarsal region. The F-scan in-shoe pressure measurement system(TEKSCAN) provided an objective measure of effect.


Avoiding Collapse: Resilience And Sustainable Development In Vulnerable Small Islands, Matthew Paul Bunce Jan 2007

Avoiding Collapse: Resilience And Sustainable Development In Vulnerable Small Islands, Matthew Paul Bunce

School of Geography, Earth and Environmental Sciences Theses

Small islands dependent on reef fisheries, farming and tourism are vulnerable to rising human and natural pressures and may target "sustainable" development. Marine Protected Areas (MPA) have a proven ability to meet ecological goals, such as restoring fisheries and preserving ecosystem function across scales. However, there is a comparative lack of scientific baseline data and social research which may help local MPA to overcome failures in achieving mixed conservation and development goals in populated coastal areas facing intense pressure. This fieldwork-based case study researched in French and Creole languages in the sub-tropical, mid-Oceanic island of Rodrigues (Mauritius, Indian Ocean) addresses …


The Marketing Strategies Of Livestock Enterprises In Objective One Regions : A Comparative Study Between Greece And United Kingdom, Lambros Tsourgiannis Jan 2007

The Marketing Strategies Of Livestock Enterprises In Objective One Regions : A Comparative Study Between Greece And United Kingdom, Lambros Tsourgiannis

School of Geography, Earth and Environmental Sciences Theses

This research aims to identify the marketing decisions made by agricultural producers in two E. U. Objective I regions and to provide insights into the reasons that such decisions are made, with a particular focus on meat and milk products. Two farm business surveys; one in the involving sheep and goat farmers in the Region of East Macedonia and Thrace (EMT11) in Greece and one in the sheep and dairy cow fanners in Cornwall, U. K. were undertaken in order to identify their marketing behaviour. This study used robust predictive models incorporating bivariate and multivariate statistical techniques in order to …


The Ecology And Genetics Of Cirsium Dissectum (L.) Hill In The British Isles And Implications For Its Conservation, Natasha De Vere Jan 2007

The Ecology And Genetics Of Cirsium Dissectum (L.) Hill In The British Isles And Implications For Its Conservation, Natasha De Vere

School of Biological and Marine Sciences Theses

The aim of this study was to research the ecology and genetics of Cirsium dissectum and to discuss the implications of the results for its conservation. The ecology of C. dissectum was described through a review of the literature. Site characteristics, plant communities and reproductive biology were investigated by examining 22 populations throughout the British Isles. Microsatellite genetic markers were used to investigate levels of genetic diversity within and between these populations. Within populations, relationships between genetic diversity, population size, fitness and habitat quality (concentrating on soil nutrients and vegetation structure) were explored using multiple regression and structural equation modelling. …


Evidence For An Olfactory Store In Working Memory?, J Andrade, L Donaldson Jan 2007

Evidence For An Olfactory Store In Working Memory?, J Andrade, L Donaldson

School of Psychology

No abstract provided.


Geochronology Of Salt-Marsh Sediments, William Alderman Marshall Jan 2007

Geochronology Of Salt-Marsh Sediments, William Alderman Marshall

School of Geography, Earth and Environmental Sciences Theses

Salt-marsh sediments can provide important achives of past sea levels if they can besecurely dated. This thesis investigates eight methods for dating salt-marsh sediments.These include traditional and established dating methods (¹⁴C dating and theradionuclides ¹³⁷Cs and ²¹ºPb) and more novel approaches to dating the deposition ofsalt-marsh sediments (palaeomagnetic dating, the use of' atmospheric stable leaddeposition, tephra chronologies, pollen markers, SCP analysis and the use ofatmospheric ¹⁴C 'bomb spike' and high-precision AMS ¹⁴C measurements). Sites wereselected to provide contrasting sediment sequences that differed both in lithology andaccumulation rates and included salt marshes from the Taf estuary (southwest Wales),the Arne Peninsula (southern …


Effects Of Hyperbaric Oxygen On Oxidative Stress, Angiogenesis Factors And Endothelial Cell Injury, Jianfeng Yuan Jan 2007

Effects Of Hyperbaric Oxygen On Oxidative Stress, Angiogenesis Factors And Endothelial Cell Injury, Jianfeng Yuan

School of Biological and Marine Sciences Theses

Hyperbaric oxygen (HBO) therapy is the administration of 100% oxygen at more than one atmosphere. It greatly improves tissue oxygenation and facilitates mechanisms of wound healing, which in turn benefits some patients with chronic wounds. A prominent fact in therapeutic HBO is the acceleration of neoangiogenesis during granulation tissue formation. Angiogenesis is a highly orchestrated event, a diverse range of cells and angiogenesis factors are involved in the process. The formation of reactive oxidative species (ROS) during HBO has been controversially considered as signalling regulator for angiogenic factors, as well as harmful originator for oxidative stress-induced cyto- and geno-toxicity in …


Statistical Contributions To Medical Research In The South West Peninsula, Hilary Patricia Sanders Jan 2007

Statistical Contributions To Medical Research In The South West Peninsula, Hilary Patricia Sanders

School of Engineering, Computing and Mathematics Theses

The papers on which this thesis is based are the result of original research work undertaken in collaboration with healthcare researchers in the South West Peninsula. Modern healthcare research involves large scale multidisciplinary projects and the Statistician's role In these projects, from concept through design and execution to the production of published papers, is crucial. Funding bodies, and in particular the Medical Research Council (MRC), expect a Statistician to be part of the project team and the statistical input and expertise included plays a key role in determining whether or not projects are funded and are subsequently successful. The selection …


The Experience Of Obesity, Its Treatment And Weight Loss: A Qualitative Study Of Overweight Couples, Brenda Potz Kieffer Jan 2007

The Experience Of Obesity, Its Treatment And Weight Loss: A Qualitative Study Of Overweight Couples, Brenda Potz Kieffer

Other Faculty of Health Theses

This study utilized a qualitative, phenomenological methodology to study obesity. The purpose was to better understand the experiences of obesity, treatment and weight loss from the perspectives of formerly obese individuals, their partners and as couples. The participants consisted of six couples mostly from rural communities. In each couple, at least one the partners had experienced weight fluctuations into the obese range and had achieved at least 50% of his or her weight loss goal. The couples participated in two semi-structured interviews, both individually and as couples. A genogram was constructed with each couple to help identify family of origin …


Magnetic Field Sensor Utilizing Magneto Impedance In Thin Film Multi-Layers, Paul Delooze Jan 2007

Magnetic Field Sensor Utilizing Magneto Impedance In Thin Film Multi-Layers, Paul Delooze

Other Faculty of Science and Engineering Theses

Since the discovery of the Magneto Impedance (MI) effect in 1994 there has been a global increase in the research devoted to understanding the effect. In certain magnetic materials, the impedance change, often referred to as the MI ratio, is in the range of 50 to 100% for an excitation current in the MHz frequency range for external magnetic fields of a few Oe. The use of thin film multilayer structures allows the increase of sensitivity and the reduction of size for MI effect to be integrated with micro magnetic sensor technologies. In the present work, we explain the origins …


Managing Community: A Philosophical Analysis Of Praxis, Alan Sanderson Jan 2007

Managing Community: A Philosophical Analysis Of Praxis, Alan Sanderson

Other Faculty of Science and Engineering Theses

If communities are to become a viable means of implementing social policy then community practitioners must individually examine their personal praxis. Therefore, in discovering a community's aims and objectives, a management model is needed that offers every practitioner a reflexive means of understanding peoples' beliefs, values, and attitudes. This proposition is critically examined through a philosophical framework that explores individuals' diverse perspectives on community, derived from their adherence to contending ontological and epistemological propositions about the social world, and its related ethical and motivational dimensions. Following a philosophical analysis, the taxonomy of social reality perspectives, developed by Dixon (2003) and …


The Rape Of Mary Raymond : A Radical View Of Rape In Mary Hays's The Memoirs Of Emma Courtney And The Victim Of Prejudice, Sarah Ann Oliver Jan 2007

The Rape Of Mary Raymond : A Radical View Of Rape In Mary Hays's The Memoirs Of Emma Courtney And The Victim Of Prejudice, Sarah Ann Oliver

Other Faculty of Arts, Humanities and Business Theses

The thesis is an examination of Mary Hays's first and second novels, The Memoirs of Emma Courtney (1796) and The Victim of Prejudice (1799) in order to claim a reworking of political and gender constructions of women that underwrite rape narratives produced in the Long Eighteenth Century. To discuss ways in which Hays's novels challenge the assumptions and constructions of femininity disseminated in earlier rape texts I have selected examples of polemic and narratives written between the 1670s and the 1790s together with some of the contemporary Radical texts which exhibit similar concerns and views expressed in the writer's feminist …


Shared Habitats: The Moverwitness Paradigm, Eila Goldhahn Jan 2007

Shared Habitats: The Moverwitness Paradigm, Eila Goldhahn

Other Faculty of Arts, Humanities and Business Theses

This practice-led research thesis analyses and visualises central components of Authentic Movement, with particular reference to the work of Dr Janet Adler. By contextualising and comparing this improvisation method with modern, post-modern and contemporary movement practices the author describes the emergence of Authentic Movement and distinguishes it from other practices. A new and original viewpoint is adopted and the practice's aesthetic, visual and empathetic characteristics are explored in relationship to and through visual art. The author, a learned Authentic Movement practitioner, critiques, deconstructs and reframes the practice from a visual arts- and performance-based, phenomenological perspective renaming it 'the MoverWitness exchange'. …


William Andrews Nesfield [1794-1881] Artist And Landscape Gardener, Shirley Rose Evans Jan 2007

William Andrews Nesfield [1794-1881] Artist And Landscape Gardener, Shirley Rose Evans

Other Faculty of Arts, Humanities and Business Theses

Contrary to past opinions William Andrews Nesfield's garden layouts were not solely designed to provide appropriate accompaniments to the Elizabethan and Jacobean revival architecture of his brother-in-law Anthony Salvin (1799-1881). Nor were they conceived chiefly to provide his wealthy patrons with a variation on the French seventeenth-century parterre-de-broderie. Undoubtedly, this device helped to forge a sympathetic bond between Nesfield and his patrons, for it had been a symbol of power and status in seventeenth-century France when it was associated with the upper echelons of French society. It therefore represented to the aristocracy and upper gentry of nineteenth-century Britain, during the …


William Andrews Nesfield (1794-1881) Artist And Landscape Gardener, Shirley Rose Evans Jan 2007

William Andrews Nesfield (1794-1881) Artist And Landscape Gardener, Shirley Rose Evans

Other Faculty of Arts, Humanities and Business Theses

Contrary to past opinions William Andrews Nesfield's garden layouts were not solely designedt o provide appropriatea ccompanimentsto the Elizabethana nd Jacobean revival architecture of his brother-in-law Anthony Salvin (1799-1881). Nor were they conceived chiefly to provide his wealthy patrons with a variation on the French seventeenth-centuryparterre-de-broderieU. ndoubtedly,t his device helpedt o forge a sympathetic bond between Nesfield and his patrons, for it had been a symbol of power and statusi n seventeenth-centurFy rancew hen it was associatedw ith the upper echelonso f Frenchs ociety. It thereforer epresentedto the aristocracya nd upper gentry of nineteenthcenturyB ritain, during the time Nesfield was …


The Challenge Of Interagency Information Sharing: A Systemic Analysis Of Two Sure Start Children's Centres, Susan Moira Richardson Jan 2007

The Challenge Of Interagency Information Sharing: A Systemic Analysis Of Two Sure Start Children's Centres, Susan Moira Richardson

Other Faculty of Arts, Humanities and Business Theses

This study investigates a problem facing professionals working in public service agencies, in the current policy context of partnership working. This is the question of how to share personal service user information across agency boundaries, so that there is minimal risk of important information being ‘lost down the cracks' between agencies, while at the same time avoiding the risk of breaching confidentiality. This study aims to understand better the day to day difficulties faced by those grappling with this problem. This research contributes to the theoretical understanding of this challenge by proposing a new model of information sharing behaviour and …


Constructing L2-Svm-Based Fuzzy Classifiers In High-Dimensional Space With Automatic Model Selection And Fuzzy Rule Ranking, Shang Ming Zhou, John Q. Gan Jan 2007

Constructing L2-Svm-Based Fuzzy Classifiers In High-Dimensional Space With Automatic Model Selection And Fuzzy Rule Ranking, Shang Ming Zhou, John Q. Gan

School of Nursing and Midwifery

No abstract provided.


A Study Of Linear Error Correcting Codes, Cen Jung Tjhai Jan 2007

A Study Of Linear Error Correcting Codes, Cen Jung Tjhai

School of Engineering, Computing and Mathematics Theses

Since Shannon's ground-breaking work in 1948, there have been two main development streams of channel coding in approaching the limit of communication channels, namely classical coding theory which aims at designing codes with large minimum Hamming distance and probabilistic coding which places the emphasis on low complexity probabilistic decoding using long codes built from simple constituent codes. This work presents some further investigations in these two channel coding development streams. Low-density parity-check (LDPC) codes form a class of capacity-approaching codes with sparse parity-check matrix and low-complexity decoder Two novel methods of constructing algebraic binary LDPC codes are presented. These methods …


Hunger-Related Intrusive Thoughts Reflect Increased Accessibility Of Food Items, Lisa Marie Berry, Jackie Andrade, Jon May Jan 2007

Hunger-Related Intrusive Thoughts Reflect Increased Accessibility Of Food Items, Lisa Marie Berry, Jackie Andrade, Jon May

School of Psychology

No abstract provided.


Paris Framed: Twentieth-Century French Writers Crossing The City, C Mansfield Jan 2007

Paris Framed: Twentieth-Century French Writers Crossing The City, C Mansfield

Plymouth Business School

Twentieth-century writers frame Paris as a locus of desire for their characters, whether working in fiction or in the more contemporary ethno¬graphic journaling exemplified by the writing of Annie Ernaux in La Vie extérieure (2000) and Journal du dehors (1993). This article draws on the critical approaches taken by Christopher Thompson (1992) and Richard Burton (1988) in their respective works on French nineteenth-century literature and uses their critical frameworks as a starting point with which to explore this travel writing of Ernaux.


The Evolution And Palaeobiogeography Of Mesozoic Planktonic Foraminifera, Wendy Hudson Jan 2007

The Evolution And Palaeobiogeography Of Mesozoic Planktonic Foraminifera, Wendy Hudson

School of Geography, Earth and Environmental Sciences Theses

In the 1960s Oberhauser and Fuchs (palaeontologists working at the Geologische Bundesanstalt in Vienna) described a range of new taxa from the Triassic of Austria that were thought to be the earliest planktonic foraminifera. The first reactions of the palaeontological community were negative but in the subsequent forty years our knowledge of Jurassic planktonic foraminifera has expanded considerably. A thorough re-evaluation of the Oberhauser and Fuchs collections in Vienna has shown that these species are probably not planktonic and that the first planktonic taxa appeared in the Toarcian. This origination in the centre of Western Tethys was followed by a …


A Generalized Method For Transfecting Root Epidermis Uncovers Endosomal Dynamics In Arabidopsis Root Hairs, Prisca Campanoni, Jens Uwe Sutter, Craig Stewart Davis, George Robert Littlejohn, Michael Robert Blatt Jan 2007

A Generalized Method For Transfecting Root Epidermis Uncovers Endosomal Dynamics In Arabidopsis Root Hairs, Prisca Campanoni, Jens Uwe Sutter, Craig Stewart Davis, George Robert Littlejohn, Michael Robert Blatt

School of Biological and Marine Sciences

SummaryProgress in analysing the cellular functions of many structural proteins has accelerated through the use of confocal microscopy together with transient gene expression. Several methods for transient expression have been developed in the past few years, but their application has seen limited success beyond a few tractable species and tissues. We have developed a simple and efficient method to visualize fluorescent proteins in Arabidopsis root epidermis using co‐cultivation of seedlings with Agrobacterium rhizogenes. The method is equally suitable for transient gene expression in other species, including Thellungiella, and can be combined with supporting molecular and biochemical analyses. The method promises …


Motivational Influences On Compliance With And Consequences Of Instructions To Suppress Stereotypes, Na Wyer Jan 2007

Motivational Influences On Compliance With And Consequences Of Instructions To Suppress Stereotypes, Na Wyer

School of Psychology

Two experiments investigated differences in compliance with instructions to suppress stereotypes as a function of prejudice-related motivations. In Experiment 1, only participants identified as high in motivation to control prejudice [Dunton, B. C., & Fazio, R. H. (1997). An individual difference measure of motivation to control prejudiced reactions. Personality and Social Psychology Bulletin, 23, 316–326] complied with suppression instructions. These participants experienced post-suppression rebound effects, but only if they were also high in prejudice. In Experiment 2, only participants identified as high in external motivation to respond without prejudice [Plant, E. A., & Devine, P. G. (1998). Internal and external …


The Geographies Of Policing, R Yarwood Jan 2007

The Geographies Of Policing, R Yarwood

School of Geography, Earth and Environmental Sciences

No abstract provided.


Preserving Deep-Sea Natural Heritage: Emerging Issues In Offshore Conservation And Management, Aj Davies, Jm Roberts, J Hall-Spencer Jan 2007

Preserving Deep-Sea Natural Heritage: Emerging Issues In Offshore Conservation And Management, Aj Davies, Jm Roberts, J Hall-Spencer

School of Biological and Marine Sciences

No abstract provided.


Hypoxia-Regulated Carbonic Anhydrase Ix Expression Is Associated With Poor Survival In Patients With Invasive Breast Cancer, Sa Hussain, R Ganesan, G Reynolds, L Gross, Et Al Jan 2007

Hypoxia-Regulated Carbonic Anhydrase Ix Expression Is Associated With Poor Survival In Patients With Invasive Breast Cancer, Sa Hussain, R Ganesan, G Reynolds, L Gross, Et Al

Peninsula Medical School

Tumour hypoxia is a microenvironmental factor related to poor response to radiation, chemotherapy, genetic instability, selection for resistance to apoptosis, and increased risk of invasion and metastasis. Hypoxia-regulated carbonic anhydrase IX (CA IX) has been studied in various tumour sites and its expression has been correlated with the clinical outcome. The purpose of this study was to investigate the correlation of CA IX expression with outcome in patients with invasive breast cancer. We conducted a retrospective study examining the effects of carbonic anhydrase IX (CA IX) on survival in patients with breast cancer. To facilitate the screening of multiple tissue …


On Computing Shannon’S Sphere Packing Bound And Applications, Mz Ahmed, Ma Ambroze, M Tomlinson Jan 2007

On Computing Shannon’S Sphere Packing Bound And Applications, Mz Ahmed, Ma Ambroze, M Tomlinson

School of Engineering, Computing and Mathematics

A new method to numerically evalu- ate Shannon’s lower bound is presented in this pa- per. This new method is based on the Incomplete Beta function and permits the exact evaluation of the Sphere Packing Bound for a large range of code sizes, rates and probability of error. Comparisons with cur- rent standards (DVB–RCS, DVB–S2 and 3GPP) are also presented and discussed. It is shown that cur- rent standard coding schemes are about 0.6dB from the Shannon Limit corrected for Binary Signalling.