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Designing Clinical Trials In Older People., C. B. Carroll, J. P. Zajicek
Designing Clinical Trials In Older People., C. B. Carroll, J. P. Zajicek
Peninsula Medical School
Adequate medical care of the increasingly ageing population requires robust clinical trial data both to inform treatment decisions, and to understand the natural history of diseases which primarily affect the elderly. However, this information is widely lacking, which is likely to have significant clinical consequences. Under-representation of older people in clinical trials is well documented, the reasons including physicians' perception, protocol eligibility criteria, and functional status requirements. Many clinical trial designs remain conservative and there is no established standardised methodology for recruiting more elderly patients with co-morbidities and disability into clinical trials. Designing clinical trials in older people poses a …
Multidimensional Epidemiological Transformations: Addressing Location-Privacy In Public Health Practice, Philip Abdelmalik
Multidimensional Epidemiological Transformations: Addressing Location-Privacy In Public Health Practice, Philip Abdelmalik
Other Faculty of Health Theses
The ability to control one’s own personally identifiable information is a worthwhile human right that is becoming increasingly vulnerable. However just as significant, if not more so, is the right to health. With increasing globalisation and threats of natural disasters and acts of terrorism, this right is also becoming increasingly vulnerable. Public health practice – which is charged with the protection, promotion and mitigation of the health of society and its individuals – has been at odds with the right to privacy. This is particularly significant when location privacy is under consideration. Spatial information is an important aspect of public …
Wild Country Hall: Children’S Learning At A Residential Outdoor Education Centre., Anthony Thomas Rea
Wild Country Hall: Children’S Learning At A Residential Outdoor Education Centre., Anthony Thomas Rea
Plymouth Institute of Education Theses
This thesis is about learning at a residential outdoor education centre [pseudonym:- Wild County Hall]. It poses and answers three questions: • How useful might discursive positioning be as a perspective on learning? • What are the discourses at Wild Country Hall and how are they different to schooling discourses? • How might neo-Liberal discursive practices, including performativity and current schooling orthodoxies have affected the pedagogic practices at this centre? The review of literature provides an overview of the key literature on outdoor, adventure and experiential learning, considering these through the lenses of learning as acquisition, participation and transformation, before …
Factors Influencing The Marine Spatial Ecology Of Seabirds: Implications For Theory, Conservation And Management, William James Grecian
Factors Influencing The Marine Spatial Ecology Of Seabirds: Implications For Theory, Conservation And Management, William James Grecian
Other Faculty of Science and Engineering Theses
Seabirds are wide-ranging apex-predators and useful bio-indicators of marine systems. Nevertheless, changes are occurring in the marine environment, and seabirds require protection from the deleterious effects of climate change, fisheries, pollution, offshore development, introduced predators and invasive species. The UK supports internationally important populations of seabirds but also has vast wind and wave resources, therefore understanding how seabirds use the marine environment is vital in order to quantify the potential consequences of further exploiting these resources. In this thesis I first describe the range of wave energy converting devices operational or in development in the UK, and review the potential …
Life Cycle Assessment Of Flax Fibres, Nilmini Pj Dissanayake
Life Cycle Assessment Of Flax Fibres, Nilmini Pj Dissanayake
Other Faculty of Science and Engineering Theses
This thesis aims to investigate the sustainability of bast fibres specifically flax fibres as the reinforcement for polymer matrix composites (referenced to glass fibres) by undertaking a quantitative Life Cycle Assessment using the eight environmental impact classification factors of global warming, acidification, eutrophication, human toxicity, aquatic toxicity, ozone depletion, photochemical oxidants creation and non-renewable/abiotic resource depletion. A data set was compiled from numerous literature sources to complete the Life Cycle Inventory for the production of flax fibres. Three scenarios were studied for the production of either flax sliver (pre-spun fibre) or yarn (post-spun fibre): low (no-till combined with warm water …
Cobalt Biogeochemistry In The Atlantic Ocean Using Flow Injection-Chemiluminescence, Rachel Shelley
Cobalt Biogeochemistry In The Atlantic Ocean Using Flow Injection-Chemiluminescence, Rachel Shelley
Other Faculty of Science and Engineering Theses
As ~ 50% of global photosynthesis occurs in marine environments, the factors regulating this process e.g. trace metal availability, have an impact on the global carbon cycle. The key cyanobacteria genera Prochlorococcus and Synechococcus have an absolute requirement for Co. Dissolved cobalt (dCo) concentrations in the open ocean are extremely low (5–120 pM). A sensitive flow injection technique using chemiluminescence detection (FI-CL) was developed (detection limit 4.5 pM dCo, RSD ≤ 4%). Seawater samples must be UV-irradiated prior to analysis, in order to liberate organically-bound Co. A field study in the Sargasso Sea, demonstrated that aerosol Co was significantly more …
Sustainable Heritage Management Practices At Visited Heritage Sites In Devon And Cornwall, Susan Elizabeth Joan Darlow
Sustainable Heritage Management Practices At Visited Heritage Sites In Devon And Cornwall, Susan Elizabeth Joan Darlow
Other Faculty of Science and Engineering Theses
Sustainability is one of the key challenges facing society in the twenty-first century. The adoption of sustainable practices in the heritage sector resonates with its long-established objectives to conserve and enhance the historic environment, although its implementation can also present significant dilemmas for the commodification, integrity, authenticity, accessibility and viability of these resources, particularly where sites are tourist attractions. The aim of this thesis was to investigate progress in the adoption of sustainable practices in heritage properties and sites in Devon and Cornwall. The findings were based on the compilation of an inventory of selected heritage resources; an extensive questionnaire …
New Statistical Methods To Derive Functional Connectivity From Multiple Spike Trains, Mohammad Shahed Masud
New Statistical Methods To Derive Functional Connectivity From Multiple Spike Trains, Mohammad Shahed Masud
Other Faculty of Science and Engineering Theses
Analysis of functional connectivity of simultaneously recorded multiple spike trains is one of the major issues in the neuroscience. The progress of the statistical methods to the analysis of functional connectivity of multiple spike trains is relatively slow. In this thesis two statistical techniques are presented to the analysis of functional connectivity of multiple spike trains. The first method is known as the modified correlation grid (MCG). This method is based on the calculation of cross-correlation function of all possible pair-wise spike trains. The second technique is known as the Cox method. This method is based on the modulated renewal …
Intrusive Thoughts, Mindfulness And Dissociation In Self-Harm, Helen Riley
Intrusive Thoughts, Mindfulness And Dissociation In Self-Harm, Helen Riley
Other Faculty of Science and Engineering Theses
This thesis presents four studies that examine the potential role that intrusive thoughts, dissociation and mindfulness in self-harming behaviours in young people and adults. A large online study was conducted with students and staff at a UK university. This examined a range of risk factors for self-harm derived from the literature, including dissociation, family background/trauma history and intrusive thoughts. This study was followed up with a qualitative study investigating triggers of self-harm, and the role of intrusive thoughts. A third study then looked at these factors in young people who were inpatients in an American psychiatric hospital, and who had …
Detecting Phytoplankton Size Class Using Satellite Earth Observation, Robert J. W. Brewin
Detecting Phytoplankton Size Class Using Satellite Earth Observation, Robert J. W. Brewin
Other Faculty of Science and Engineering Theses
A new range of multi-plankton biogeochemical models have recently been developed, designed to advance our understanding of the ocean carbon cycle to improve predictions of its future influence on climate. Synoptic measurements of the different phytoplankton communities are required to validate and ultimately improve such models. Measuring ocean colour from satellite is the only method currently available for synoptically monitoring wide-area properties of ocean ecosystems, such as phytoplankton chlorophyll biomass. Recently, a variety of bio-optical methods have been established that use satellite data to identify and differentiate between either phytoplankton functional types (PFTs) or phytoplankton size classes (PSCs). In this …
Elucidating The Relative Importance Of The Bacterial And Fungal Feeding Channels Within The Soil Food Web Under Differing Land Managements, Felicity Victoria Crotty
Elucidating The Relative Importance Of The Bacterial And Fungal Feeding Channels Within The Soil Food Web Under Differing Land Managements, Felicity Victoria Crotty
Other Faculty of Science and Engineering Theses
The overall aim of this thesis was to elucidate the relative importance of the bacterial and fungal energy channels within the soil food web and to differentiate and appreciate the differences in niche of the soil fauna when affected by differing land management. Feeding niche of the soil fauna is ambiguous and has been previously determined by observation, inference or biochemical studies. One method that can determine feeding preferences in situ is the use of stable isotopes. Stable isotopes trace the passage of C and N through different trophic levels, both at natural abundance and by the addition of a …
The Visible Invisible Object: A Photographic Enquiry 'Recording' A Lived Life, David George Sullivan
The Visible Invisible Object: A Photographic Enquiry 'Recording' A Lived Life, David George Sullivan
Other Faculty of Arts, Humanities and Business Theses
Abstract The Visible Invisible Object: A Photographic Enquiry ‘Recording’ A Lived Life David George Sullivan This practice-led research project is centred upon a photographic ‘recording’ of everyday ‘objects’, which has been built up since 2004. I have ‘recorded’ everyday ‘objects’ that I have experienced using the camera lens, selected because of the form of the ‘thing’ and to act as a vehicle to signify the ‘encounter’, or a related signified memory. The images act as signifiers. The aim of this practice is to ‘record’ ‘encounters’ and memories through the positing of ‘objects’; to make a selection from this body of …
Late Medieval Roof Bosses In The Churches Of Devon, Susan Andrew
Late Medieval Roof Bosses In The Churches Of Devon, Susan Andrew
Other Faculty of Arts, Humanities and Business Theses
Susan Andrew LATE MEDIEVAL ROOF BOSSES IN THE CHURCHES OF DEVON Abstract The extensive survival of late medieval bosses in the roofs of many parish churches in Devon has long been recognised. These carvings escaped the widespread destruction of images during the Reformation through their relative inaccessibility, and yet most have never before been recorded; nor has systematic study been made of their design, their positioning within a sacred space, or the ways in which they may have been viewed and used by a largely illiterate audience. This thesis rectifies this oversight in its detailed documentation and photography of figural …
Ageing Futures: Towards Cognitively Inclusive Digital Media Products, John Charles Vines
Ageing Futures: Towards Cognitively Inclusive Digital Media Products, John Charles Vines
Other Faculty of Arts, Humanities and Business Theses
This thesis is situated in a moment when the theory and practice of inclusive design appears to be significantly implicated in the social and economic response to demographic changes in Western Europe by addressing the need to reconnect older people with technology. In light of claims that cognitive ageing results in an increasing disconnection from novel digital media in old age, inclusive design is apparently trapped in a discourse in which digital media products and interfaces are designed as a response to a deterministic decline in abilities. The thesis proceeds from this context to ask what intellectual moves are required …
Eniatype: Transdisciplinary Practice For Methodologies Of Communication, Shaun Patrick Murray
Eniatype: Transdisciplinary Practice For Methodologies Of Communication, Shaun Patrick Murray
Other Faculty of Arts, Humanities and Business Theses
The thesis demonstrates a rethinking of methodologies of communication through ecological design. Human communication and ecological accountability are inextricably linked in architectural design: the current global ecological crisis underscores this fundamental connection. Within architectural practice the communication from architect to participant or environment is not at all straightforward. This is also true of the dyadic relation between context, design and communication in architectural education. Notational systems within architectural education used as a communication tool have made the composition of architecture an activity like the composition of fiction: the activity of communication. So deep is the connection between architecture and communication …
Gender, Genre And Politics In The Literary Work Of Sylvia Townsend Warner, Mary Elizabeth Jacobs
Gender, Genre And Politics In The Literary Work Of Sylvia Townsend Warner, Mary Elizabeth Jacobs
Other Faculty of Arts, Humanities and Business Theses
This thesis brings together a collection of works, all of which explore ways in which the prolific twentieth-century writer, Sylvia Townsend Warner, engaged with politics. A committed communist from the 1930s onwards, Warner was also a feminist writer and the works discussed here examine the interface between the politics of gender and the politics of the left. The sexual politics of Warner's private life with her long-term partner, Valentine Ackland, also inform her writings, often providing a homosexual undercurrent that offers multiple possible readings. Warner worked in a range of genres over a writing career that spanned five decades. The …
Ludics For A Ludic Society. The Art And Politics Of Play, Margarete Jahrmann
Ludics For A Ludic Society. The Art And Politics Of Play, Margarete Jahrmann
Other Faculty of Arts, Humanities and Business Theses
This dissertation provides an analysis of, and critical commentary on, the practice of playfulness as persistent phenomenon in the arts, technology and theory. Its aim is to introduce political reflections on agency through the study of playful technological artefacts, which were largely ignored in the recent discussions on game and play. Following the critical analysis of historic discourses and actual studies of play under differing auspices, and in order to understand play as inherently political agency, this thesis’ research question addresses the immersive effects of playful agency in symbolic exchange systems and in the material consciousness of the player. This …
A Cortical Model Of Object Perception Based On Bayesian Networks And Belief Propagation., Salvador Durá-Bernal
A Cortical Model Of Object Perception Based On Bayesian Networks And Belief Propagation., Salvador Durá-Bernal
Other Faculty of Science and Engineering Theses
Evidence suggests that high-level feedback plays an important role in visual perception by shaping the response in lower cortical levels (Sillito et al. 2006, Angelucci and Bullier 2003, Bullier 2001, Harrison et al. 2007). A notable example of this is reflected by the retinotopic activation of V1 and V2 neurons in response to illusory contours, such as Kanizsa figures, which has been reported in numerous studies (Maertens et al. 2008, Seghier and Vuilleumier 2006, Halgren et al. 2003, Lee 2003, Lee and Nguyen 2001). The illusory contour activity emerges first in lateral occipital cortex (LOC), then in V2 and finally …
The Construction Of Sport Heritage Attractions, Gregory Ramshaw
The Construction Of Sport Heritage Attractions, Gregory Ramshaw
Journal of Tourism Consumption and Practice
Sport can be heritage, and sport heritage attractions such as halls of fame, museums, and stadium tours can be one of the more potent forms of heritage tourism. However, few studies have examined sport heritage attractions, nor considered their construction. This paper examines three ways in which sport heritage attractions are constructed, exploring in particular the human dimensions of sport heritage, the link between sport heritage and legacy, and the relationship between sport heritage, tourism and globalization. Several outcomes of these constructions are examined, both in terms of the representation sport heritage as well as implications for the attractions themselves. …
Diversification Of The Tourist Landscape On Ghana’S Atlantic Coast: Forts, Castles And Beach Hotel / Resort Operations In The Tourism Industry, Edward Addo
Journal of Tourism Consumption and Practice
European settlements, trans-Atlantic trade in commodities and slaves, and colonization are indispensable components of Ghana’s political history, heritage, and tourism industry. European forts and castles built as far back as 1482 still characterize the Atlantic coast of Ghana. Since March 6, 1957 when Ghana became the first sub-Sahara African country to gain political independence from European colonial rule, the country has faced many socio-economic and political challenges. Tourism did not receive significant political attention until the late 1990s. In more recent years, the industry has experienced remarkable growth and increasing operations of beach hotels and resorts on the Atlantic coast …
Representing ‘The Real’: Realism And Visual Culture In Tourism, Leisure And Ethnography, Ian Gilhespy, Dave Harris
Representing ‘The Real’: Realism And Visual Culture In Tourism, Leisure And Ethnography, Ian Gilhespy, Dave Harris
Journal of Tourism Consumption and Practice
The collection and use of visual evidence is widespread in a wide range of academic and professional activities. The paper explores the similarities and differences of a range of related phenomena: realism, documentary and authenticity. The status of the ‘realism effect’ is evaluated in a range of leisure activities with an emphasis on tourism and the significance of realist texts in popular culture in narrative and nonnarrative forms. The creative treatment of the representation of reality in the documentary tradition is highlighted. The paper emphasises the pleasures to be gained from ‘experiencing the real’ using semiotics and film theory, in …
Book Reviews: Journal Of Tourism Consumption And Practice Volume 3 No.1 2011, Natalie Hooton, Maximiliano E. Korstanje
Book Reviews: Journal Of Tourism Consumption And Practice Volume 3 No.1 2011, Natalie Hooton, Maximiliano E. Korstanje
Journal of Tourism Consumption and Practice
Sex, Tourism and the Postcolonial Encounter: Landscapes of Longing in Egypt. Jessica Jacobs (2010) Ashgate, Aldershot. Pp 154 ISBN: 9780754647881 Con el Corazón Mirando al Sur. Transformaciones en el Sur de la Ciudad de Buenos Aires. (With the Heart seeing Southward: refurbishments on South of Buenos Aires). Hilda Herzer (Editor) (2008) Espacio Editorial, Buenos Aires. Pp. 367. ISBN 978-950-802-291-2.
Tracking Tourists: Mobility, Experiences And The Supply-Demand Gap In A Swedish Mountain Resort, Bo Svensson, Robert Pettersson, Ingrid Zakrisson
Tracking Tourists: Mobility, Experiences And The Supply-Demand Gap In A Swedish Mountain Resort, Bo Svensson, Robert Pettersson, Ingrid Zakrisson
Journal of Tourism Consumption and Practice
This study focuses on method development in the areas of visitor and experience tracking. It is about understanding experiences in a time-spatial framework made up by visits to a particular destination. These issues were identified as central for destination stakeholders in their attempts at meeting or exceeding visitor expectations at their destination. Development of methods here thus aims at supporting producers in generating such knowledge. The approach that emerged was to track and measure tourism experiences with the help of Global Positioning System (GPS) technology, follow-up surveys and in-depth interviews. The empirical findings are from a case study of the …
Hispaniola: The Future Tourism Destination Of The Caribbean?, Hugues Séraphin
Hispaniola: The Future Tourism Destination Of The Caribbean?, Hugues Séraphin
Journal of Tourism Consumption and Practice
No abstract provided.
Conference Reports: Journal Of Tourism Consumption And Practice Volume 3 No.2 2011, Graham Busby
Conference Reports: Journal Of Tourism Consumption And Practice Volume 3 No.2 2011, Graham Busby
Journal of Tourism Consumption and Practice
British and American Studies XXI, Timisoara, 19-21 May 2011 Sixth Annual International Conference on Tourism, held at St George Lycabettus Hotel, Athens, 1-4 July 2010
Book Review: Journal Of Tourism Consumption And Practice Volume 3 No.2 2011, Les Roberts
Book Review: Journal Of Tourism Consumption And Practice Volume 3 No.2 2011, Les Roberts
Journal of Tourism Consumption and Practice
No abstract provided.
Modelling Coarse-Grained Beach Profile Evolution, Mohamad Hidayat Jamal
Modelling Coarse-Grained Beach Profile Evolution, Mohamad Hidayat Jamal
Other Faculty of Science and Engineering Theses
Coarse-grained beaches are particularly prevalent in the UK, composed of accumulations of either gravel, or mixed sand and gravel sediments. The aim of the work presented in this thesis is to improve capabilities for predicting coarse-grained beach 2D profile development. In particular, the effects of infiltration and sediment sorting are considered. In this study, the public domain numerical model, XBeach (v12) is developed further. This model was initially developed for studying sandy environments especially for the case of dune erosion. Here, the model is modified to enhance its capability to predict beach profile change on coarse-grained beaches. Improvements include: use …
Pyramidal Cell Diversity In The Rat Prefrontal Cortex: Electrophysiology, Dopamine Modulation And Morphology, Ullrich Bartsch
Pyramidal Cell Diversity In The Rat Prefrontal Cortex: Electrophysiology, Dopamine Modulation And Morphology, Ullrich Bartsch
Other Faculty of Science and Engineering Theses
The prefrontal cortex (PFC) is critically involved in many higher cognitive functions such as goaldirected behaviour, affective behaviour and especially working memory. In vivo extracellular recordings of PFC neural activity during working memory tasks show high variety in observed spiking patterns. These complex dynamics are critically shaped by intrinsic, synaptic and structural parameters of respective prefrontal networks. Moreover, dopamine (DA) is crucial for correct functioning of the PFC during working memory tasks. DA modulates a number of synaptic and intrinsic biophysical properties of single neurons, in particular deep layer pyramidal cells, which represent the major output neurons of the PFC. …
The Molecular And Behavioural Ecology Of Click Beetles (Coleoptera: Elateridae) In Agricultural Land, Carly Marie Benefer
The Molecular And Behavioural Ecology Of Click Beetles (Coleoptera: Elateridae) In Agricultural Land, Carly Marie Benefer
Other Faculty of Science and Engineering Theses
The larvae (wireworms) of some click beetle genera inhabit the soil in agricultural land and are crop pests. In the UK, a pest complex of Agriotes species, A. obscurus, A. sputator and A. lineatus, has been identified as the cause of the majority of damage. However, studies on their ecology are lacking, despite knowledge of this being important for the development of sustainable risk assessment and pest management strategies, in part due to the morphologically cryptic nature of wireworms. The ecology of economically important click beetle species was investigated, focusing on UK Agriotes species. The relationship between sex pheromone trapped …
Full-Field Modelling Of Crack Tip Shielding Phenomena, Yanwei Lu
Full-Field Modelling Of Crack Tip Shielding Phenomena, Yanwei Lu
Other Faculty of Science and Engineering Theses
The application of fracture mechanics to engineering design has provided significant advances in understanding of the causes and mechanisms of failure and crack growth. Despite this, there are still some aspects that remain incompletely understood, such as the crack closure/crack shielding effect. The presence of crack closure/shielding acts to reduce . The mechanisms of crack closure/shielding are complicated, and have not been fully understood. This work focuses on the plasticity-induced crack tip shielding mechanism and presents a novel approach to characterise the elastic stress fields under the influence of the plastic enclave surrounding the crack tip. The model is successfully …