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Another Gap On The Rota: A Scoping Review Of Attrition From Specialty Training In Secondary Care, Hannah Gillespie, Megan E.L. Brown, Nicola Brennan, Bryan Burford, Gillian Vance Apr 2025

Another Gap On The Rota: A Scoping Review Of Attrition From Specialty Training In Secondary Care, Hannah Gillespie, Megan E.L. Brown, Nicola Brennan, Bryan Burford, Gillian Vance

Peninsula Medical School

Background The healthcare workforce is in crisis. Despite a competitive selection process, a substantial number of doctors leave specialty training (ST) programmes prematurely. This attrition causes increased costs for the National Health Service, exacerbates workforce shortages and threatens quality and safety of care. It also increases pressure on trainees who remain, further compounding the risk of attrition. There is an urgent need to understand why doctors leave ST in order to find ways to maintain the training pipeline from ST to consultant. Objectives We aimed to understand what is known about why doctors choose to leave ST programmes in secondary …


Effective Protection Of Essential Fish Habitat Requires Understanding Fish Spatial Ecology - Lessons Learnt From Protected European Bass Nursery Areas, Thomas Stamp, Elizabeth West, James E Stewart, Shaun Plenty, Tim Robbins, Emma Sheehan, Jonathan Grabowski Apr 2025

Effective Protection Of Essential Fish Habitat Requires Understanding Fish Spatial Ecology - Lessons Learnt From Protected European Bass Nursery Areas, Thomas Stamp, Elizabeth West, James E Stewart, Shaun Plenty, Tim Robbins, Emma Sheehan, Jonathan Grabowski

School of Biological and Marine Sciences

Spatial management is a widely used technique to protect sessile species or habitats. Protection of essential fish habitat is increasinglybeing recognized globally within fisheries management policies, requiring further practical assessments within temperate fisheries. Weprovide a case study for the efficacy of spatially protecting nursery sites for a highly mobile species—the European bass (Dicentrarchuslabrax). Using acoustic telemetry, 146 individual fish were tracked for up to 812 days across three independent protected bass nurseryareas in the Southwest UK. Within site boundaries commercial fisheries are seasonally restricted to protect vulnerable life stages.Tagged fish were re-detected >5 million times. Detections at receivers highlighted activity …


“We're Not One-Box Issue People”: Intersectional Perspectives On Lgbtq+ Mental Health In Schools: A Uk Qualitative Study With Students, Staff And Training Providers, Charlotte Woodhead, Amy Morgan, Ibrahim Sabra, Sara Sabra, Lukasz Konieczka, Gemma Knowles, Emily Cunningham, Juliet Dryud, Liberty Elliott, Lauren Ige, Angela Mascolo, E. Singh, Katharine Rimes Apr 2025

“We're Not One-Box Issue People”: Intersectional Perspectives On Lgbtq+ Mental Health In Schools: A Uk Qualitative Study With Students, Staff And Training Providers, Charlotte Woodhead, Amy Morgan, Ibrahim Sabra, Sara Sabra, Lukasz Konieczka, Gemma Knowles, Emily Cunningham, Juliet Dryud, Liberty Elliott, Lauren Ige, Angela Mascolo, E. Singh, Katharine Rimes

School of Psychology

Abstract There is limited intersectionality-informed, contextually diverse qualitative research on school experiences of LGBTQ+ students and links to mental health. Focusing on racialized, ethnic minority and religious/faith groups, this coproduced UK study examines how: 1) sexual and/or gender diverse students with intersecting minoritized identities experience school; 2) school environments could better support their mental health; and 3) what shapes school inclusion initiatives. In-depth interviews and focus groups were conducted with 22 staff members, 32 students (13–19 years), and nine LGBTQ+ school inclusion training providers. The sample was diverse across gender and sexual identity, race/ethnicity, religion and context. Data were analysed …


Trapping The Effects Of Tobacco Smoking: The Regulation And Function Of Acp5 Expression In Lung Macrophages, Suzanne H. Willems, Shilei Qian, Pernilla Lång, Bjarne E. Overtoom, Sina Alimostafazadeh, Rocío Fuentes-Mateos, Gwenda F. Vasse, T. Anienke Van Der Veen, Jelmer Vlasma, Marina H. De Jager, Victor Guryev, Gyorgy Fejer, Göran Andersson, Barbro N. Melgert Apr 2025

Trapping The Effects Of Tobacco Smoking: The Regulation And Function Of Acp5 Expression In Lung Macrophages, Suzanne H. Willems, Shilei Qian, Pernilla Lång, Bjarne E. Overtoom, Sina Alimostafazadeh, Rocío Fuentes-Mateos, Gwenda F. Vasse, T. Anienke Van Der Veen, Jelmer Vlasma, Marina H. De Jager, Victor Guryev, Gyorgy Fejer, Göran Andersson, Barbro N. Melgert

School of Biomedical Sciences

Tartrate-resistant acid phosphatase [TRAP, gene acid phosphatase 5 (Acp5; gene name for TRAP)] is highly expressed in alveolar macrophages with proposed roles in lung inflammation and lung fibrosis development. We previously showed that its expression and activity are higher in lung macrophages of smokers and patients with chronic obstructive pulmonary disease (COPD), suggesting involvement in smoke-induced lung damage. In this study, we explored the function of TRAP and regulation of its different mRNA transcripts (Acp5 201-206) in lung tissue exposed to cigarette smoke to elucidate its function in alveolar macrophages. In mice exposed to cigarette smoke or air for 4–6 …


Eight Weeks Of High-Intensity Interval Training Alters The Tongue Microbiome And Impacts Nitrate And Nitrite Levels In Previously Sedentary Men, Annabel Simpson, Andrea M. Pilotto, Lorenza Brocca, Raffaele Mazzolari, Bob T. Rosier, Miguel Carda-Dieguez, Patricia Casas-Agustench, Raul Bescos, Simone Porcelli, Alex Mira, Chris Easton, Fiona L. Henriquez, Mia Burleigh Apr 2025

Eight Weeks Of High-Intensity Interval Training Alters The Tongue Microbiome And Impacts Nitrate And Nitrite Levels In Previously Sedentary Men, Annabel Simpson, Andrea M. Pilotto, Lorenza Brocca, Raffaele Mazzolari, Bob T. Rosier, Miguel Carda-Dieguez, Patricia Casas-Agustench, Raul Bescos, Simone Porcelli, Alex Mira, Chris Easton, Fiona L. Henriquez, Mia Burleigh

School of Health Professions

Nitric oxide (∗NO) is a key signalling molecule, produced enzymatically via ∗NO synthases (NOS) or following the stepwise reduction of nitrate to nitrite via oral bacteria. Exercise training upregulates NOS expression and improves systemic health, but its effect on oral health, and more particularly the oral microbiome, has not been investigated. We used an exercise training study design to investigate changes in the tongue dorsum microbiome, and in nitrate and nitrite levels in the saliva, plasma and muscle, before, during and after an exercise training period. Eleven untrained males (age 25 ± 5 years, mass 64.0 ± 11.2 kg, stature …


Data Driven Multi-Objective Optimization Of The Scheduling For Towing A Floating Offshore Wind Turbine Between Assembly Port And Installation Location Throughout A Year, Frédéric Le Pivert, Adam Roberts, Adan Lopez-Santander, Matthew Craven, Saeid Kazemi Apr 2025

Data Driven Multi-Objective Optimization Of The Scheduling For Towing A Floating Offshore Wind Turbine Between Assembly Port And Installation Location Throughout A Year, Frédéric Le Pivert, Adam Roberts, Adan Lopez-Santander, Matthew Craven, Saeid Kazemi

School of Engineering, Computing and Mathematics

High demand for the installation of floating offshore wind turbines over the coming years is likely to place significant pressure on ports and installation vessels. Optimization of the routes between ports and farms and the towing schedule when transporting equipment is therefore critical to reducing operation timescales and carbon emissions. This paper presents two series of multi-objective optimizations for minimizing the timescale and carbon emissions for the case of an IEA 15 MW turbine on a VolturnUS-S platform being wet towed through the English Channel to the Celtic Sea. The study makes use of the Maritime Simulation Laboratory (MSL) Ship …


Cost Utility Of Specialist Physiotherapy For Functional Motor Disorder (Physio4fmd): Economic Analysis Of A Pragmatic Randomized Controlled Trial, Jonathan Marsden Apr 2025

Cost Utility Of Specialist Physiotherapy For Functional Motor Disorder (Physio4fmd): Economic Analysis Of A Pragmatic Randomized Controlled Trial, Jonathan Marsden

School of Health Professions

Background and ObjectivesFunctional motor disorder (FMD), a motor-dominant variant of functional neurologic disorder, is a disabling condition associated with high health and social care resource use and poor employment outcomes. Specialist physiotherapy presents a possible treatment option, but there is limited evidence for clinical effectiveness and cost-effectiveness. Physio4FMD is a multicenter randomized controlled trial of specialist physiotherapy for FMD compared with treatment as usual (TAU). The aim of the analysis was to conduct a randomized trial based on economic evaluation of specialist physiotherapy compared with TAU.MethodsEleven centers in England and Scotland randomized participants 1:1 to specialist physiotherapy or TAU (referral …


Recomendaciones Para El Diseño De La Realidad Virtual Para Las Personas Mayores, Marius Varga, Leonie Cooper, Hannah Bradwell, Gaudl Swen, Alejandro Veliz Reyes, Ray Jones Apr 2025

Recomendaciones Para El Diseño De La Realidad Virtual Para Las Personas Mayores, Marius Varga, Leonie Cooper, Hannah Bradwell, Gaudl Swen, Alejandro Veliz Reyes, Ray Jones

School of Nursing and Midwifery

No abstract provided.


‘Livewell With Dementia? An Evaluation Of A Pilot Post-Diagnostic Psychoeducation Group For People Diagnosed With Dementia’, Helen Idusohan-Moizer, Oliver T. Neale, Jonathan Moizer, Nicole Quinn Apr 2025

‘Livewell With Dementia? An Evaluation Of A Pilot Post-Diagnostic Psychoeducation Group For People Diagnosed With Dementia’, Helen Idusohan-Moizer, Oliver T. Neale, Jonathan Moizer, Nicole Quinn

School of Psychology

Background: This pilot study reports the evaluation of 30 post-diagnostic, five-week structured psychoeducational intervention groups for people recently diagnosed with dementia, facilitated across Livewell CIC, Plymouth, UK.Method: Two-hundred-and-thirteen individuals were recruited using a convenience sampling methodology. A total of 167 participants (Females N=86, 51.50%, mean age 78.72, ± 8.70; Males N=81, 48.50%, mean age 78.20, ±8.21, overall mean age = 78.47, ±8.45) attended at least one session. Eighty participants completed the programme over a 12-month period.Results: Pre- and post-baseline questionnaires were analysed descriptively. Weekly sessions were analysed using an exploratory qualitative descriptive research design. Post-group evaluation revealed that the group …


Beyond Climate Change: A Model Of Sustainable Development For The Maritime Industry, David Adkins Apr 2025

Beyond Climate Change: A Model Of Sustainable Development For The Maritime Industry, David Adkins

Plymouth Business School

Recent discussions on sustainable development in the maritime industry have focused on climate change, emissions reduction, and future fuels. While vital for global trade and climate management, these topics are only part of the broader sustainable development agenda. The United Nations Sustainable Development Goals (UN SDGs) highlight the need to expand this conversation. Through a series of interviews, this study aims to develop a sustainable development model tailored to the maritime industry. Defining the maritime industry, and contextualising sustainable development to the sector provides significant challenges. The industry’s diversity complicates any definition as it encompasses shipping, maritime services, shipbuilding, education, …


Investigating Appropriate Artificial Intelligence Approaches To Reliably Predict Coastal Wave Overtopping And Identify Process Contributions, Michael Mcglade, Nieves Valiente, Jennifer M. Brown, Christopher Stokes, Tim Poate Apr 2025

Investigating Appropriate Artificial Intelligence Approaches To Reliably Predict Coastal Wave Overtopping And Identify Process Contributions, Michael Mcglade, Nieves Valiente, Jennifer M. Brown, Christopher Stokes, Tim Poate

School of Biological and Marine Sciences

Predicting coastal wave overtopping is a significant challenge, exacerbated by climate change, increasing the frequency of severe flooding and rising sea levels. Digital twin technologies, which utilise artificial intelligence to mimic coastal processes and dynamics, may offer new opportunities to predict coastal wave overtopping and flooding reliably and computationally efficiently. This study investigates the effectiveness of training various artificial intelligence models using wave buoy, meteorological, and recorded coastal wave overtopping observations to predict the occurrence and frequency of overtopping at 10-minute intervals. These models have the potential for future large-scale global applications in estimating wave overtopping and flood forecasting, particularly …


Machine Learning To Predict Stroke Risk From Routine Hospital Data: A Systematic Review, William Heseltine-Carp, Megan Courtman, Daniel Browning, Aishwarya Kasabe, Michael Allen, Adam Streeter, Emmanuel Ifeachor, Martin James, Stephen Mullin Apr 2025

Machine Learning To Predict Stroke Risk From Routine Hospital Data: A Systematic Review, William Heseltine-Carp, Megan Courtman, Daniel Browning, Aishwarya Kasabe, Michael Allen, Adam Streeter, Emmanuel Ifeachor, Martin James, Stephen Mullin

School of Engineering, Computing and Mathematics

Purpose: Stroke remains a leading cause of morbidity and mortality. Despite this, current risk stratification tools such as CHA2DS2-VASc and QRISK3 are of limited accuracy, particularly in those without a diagnosis of atrial-fibrillation. Hence, there is a need for more accurate stroke risk prediction models. Machine-learning (ML) may provide a solution to this by leveraging existing routine hospital databases to build accurate stroke risk prediction models and identify novel risk factors for stroke. Aims: In this systematic review we appraise current research using ML to predict stroke risk from routine hospital data. Based on these findings …


G-Distance: On The Comparison Of Model And Human Heterogeneity, Lenard Dome, Andy J. Wills Apr 2025

G-Distance: On The Comparison Of Model And Human Heterogeneity, Lenard Dome, Andy J. Wills

School of Psychology

Models are often evaluated when their behavior is at its closest to a single, sometimes averaged, set of empirical results, but this evaluation neglects the fact that both model and human behavior can be heterogeneous. Here, we develop a measure, g-distance, which considers model adequacy as the extent to which models exhibit a similar range of behaviors to the humans they model. We define g as the combination of two easily interpretable dimensions of model adequacy: accommodation and excess flexibility. We apply this measure to five models of an irrational learning effect, the inverse base-rate effect. g-Distance identifies two models, …


Encountering Coasts: The Contested Geographies Of Young People's Coastal Citizenship[S], Mark Holton Mar 2025

Encountering Coasts: The Contested Geographies Of Young People's Coastal Citizenship[S], Mark Holton

School of Geography, Earth and Environmental Sciences

This paper examines the contested geographies of young people's citizenship practices and performances in marine and coastal environments. This is important in developing original knowledge of how encounters with new and different coastal places, practices, people, morals and ethics can affect young people's citizenship practices and performances and how young people relate meaningfully with[in] coastal environments. Using a novel digital scrapbooking technique and qualitative interviews, conducted with 22 young adults aged 18–30 in Plymouth, UK, this paper examines how and why young people's everyday engagements and encounters with coastal environments can shape their understandings of environmental and social care. In …


Working Within A Perfect Storm: The Current Uk Care Crisis In Community Neurorehabilitation, Alyson Norman Mar 2025

Working Within A Perfect Storm: The Current Uk Care Crisis In Community Neurorehabilitation, Alyson Norman

School of Psychology

It will not have escaped the notice of our readers that there is a crisis in social care in the UK. This is not just because of a failure of integration between health services and community care provision, but because of the effects of COVID, and because of a shortage of care workers which the British media has widely reported as becoming more acute due to the UK leaving the European Union. The effects of this shortage will have been experienced by anyone involved in catastrophic injury litigation who will have heard case managers routinely reporting problems in recruiting care …


How Many Ways Are There To Measure A Tree? – An Experiment In Cross-Disciplinarity, Kate Pahl, Samyia Ambreen, Khawla Badwan, Simon Carr, David Cooper, Elizabeth Curtis, Ian Davenport, Abigail Hackett, Peter Kraftl, Peter Lawrence, Emily Lines, David CườNg Nguyễn, Caitlin Nunn, Steve Pool, Jennifer Rowntree, Ed Schofield, Johan Siebers, Jo Vergunst Mar 2025

How Many Ways Are There To Measure A Tree? – An Experiment In Cross-Disciplinarity, Kate Pahl, Samyia Ambreen, Khawla Badwan, Simon Carr, David Cooper, Elizabeth Curtis, Ian Davenport, Abigail Hackett, Peter Kraftl, Peter Lawrence, Emily Lines, David CườNg Nguyễn, Caitlin Nunn, Steve Pool, Jennifer Rowntree, Ed Schofield, Johan Siebers, Jo Vergunst

School of Biological and Marine Sciences

This article takes a transdisciplinary approach to a relatively simple-sounding task – tree measuring. It asks the question, ‘How many ways are there to measure a tree?’, in order to provoke a discussion of our different ways of knowing. It attempts to engage a reader in thinking about disciplines and what they do. It does so by sharing insights from a project in which diverse scholars, practitioners and children came together for the common purpose of producing engaged knowledge. The experience of reading the article should prompt questions about whose knowledge counts and why, and the value of university research …


Experimental-Numerical Model Comparison Of A Dynamic Power Cable For A Floating Offshore Wind Turbine, Anna Holcombe, Martyn Hann, Scott Brown, Shanshan Cheng, Robert Rawlinson-Smith, Rachel Nicholls-Lee, Tom Tosdevin, Emma Edwards, Kieran Monk Mar 2025

Experimental-Numerical Model Comparison Of A Dynamic Power Cable For A Floating Offshore Wind Turbine, Anna Holcombe, Martyn Hann, Scott Brown, Shanshan Cheng, Robert Rawlinson-Smith, Rachel Nicholls-Lee, Tom Tosdevin, Emma Edwards, Kieran Monk

School of Engineering, Computing and Mathematics

Dynamic power cables for floating offshore wind turbines (FOWTs) are designed using global numerical modelling tools, to optimise cable configuration. The presented study is a comparison between a global numerical model and a scale physical model, of a dynamic power cable during an operational sea state and a 1-in-50-year storm. Ocean basin experiments were performed with a 1:70 scale model of a dynamic power cable, connected in a tethered wave configuration to a semi-submersible FOWT in water depth representing 70 m, in the COAST laboratory at the University of Plymouth. Measured values of the physical model were used in the …


A Micro-Computed Tomographic Evaluation Of Root Canal Morphology Of Mandibular First Molars In A Black South African Subpopulation, Casper Jonker, Federico Foschi, Ericka Noelle L’Abbé, Anna Catherina Oettlé Mar 2025

A Micro-Computed Tomographic Evaluation Of Root Canal Morphology Of Mandibular First Molars In A Black South African Subpopulation, Casper Jonker, Federico Foschi, Ericka Noelle L’Abbé, Anna Catherina Oettlé

Peninsula Dental School

Abstract: Background: This study evaluates the root canal anatomy (main and accessory canals) of mandibular first molars in Black South Africans using micro-computed tomography. The effect of sex, arch side, and age are also investigated. Methods: The number of root canals in each tooth and individual roots (including an observation of the middle-mesial and middle-distal canals), the number of accessory canals, accessory canal type, root canal thirds, and the prevalence of apical deltas were recorded. A chi-squared test of association (p < 0.05) was used to report on variables (sex, arch sides, and age). Results: In most teeth, either three (55.81%) or four canalled (24.42%) configurations were present. The middle-mesial canal was found in 18.6% of teeth (males and females), with a higher prevalence among females (23.68%). The middle-distal canal was found in 3.49% of teeth. Chamber canals were identified in 4.7% of teeth. Accessory canals most likely located in the apical third were found in approximately 84.9% and 86.1% of mesial roots and distal roots, respectively. Apical deltas were identified in 15.12% of mesial and 20.93% of distal roots. Conclusions: Root canal anatomy in this population is diverse and includesdifferences in arch sides between the sexes.


“Combined With Homelessness, It’S Just A Nightmare”: A Qualitative Study Exploring How People Experiencing Homelessness Perceive Mental Health And Mental Health Services, Simone Stedmon, Pete Keohane Mar 2025

“Combined With Homelessness, It’S Just A Nightmare”: A Qualitative Study Exploring How People Experiencing Homelessness Perceive Mental Health And Mental Health Services, Simone Stedmon, Pete Keohane

School of Psychology

People experiencing chronic homelessness (PECH) have relatively poor mental health. Whilst trauma and psychologically informed services are becoming more commonplace and demonstrate positive outcomes, they are still underutilised by PECH. Furthermore, little is known about how PECH understand their own mental health. This qualitative study explores PECH’s perceptions of mental health, mental health services, and any perceived barriers or facilitators to access. Eleven PECH participated in semi-structured interviews. Interpretative Phenomenological Analysis was used to make sense of the transcripts, and five overarching group experiential themes were created: ‘Origins of Mental Health’, ‘Understanding of Mental Health Difficulties’, ‘Experiences of Help-Seeking and …


A Common Terminology To Unify Research And Conservation Of Coralline Algae And The Habitats They Create, Victor L Jardim, Jacques Grall, M.  Beatriz Barros-Barreto, Anaëlle Bizien, Thomas Benoit, Juan C Braga, Juliet Brodie, Thomas Burel, Andrea Cabrito, Guillermo Diaz-Pulido, Patrick Gagnon, Jason M Hall-Spencer, Mathieu Helias, Paulo Antunes Horta, Siddhi Joshi, Nick A Kamenos, Regina Kolzenburg, Erik C Krieger, Erwann Legrand, Tessa M Page, Viviana Peña, Federica Ragazzola, Lina M Rasmusson, Francesco Rendina, Nadine Schubert, João Silva, Frederico T  S Tâmega, Adeline Tauran, Heidi L Burdett Mar 2025

A Common Terminology To Unify Research And Conservation Of Coralline Algae And The Habitats They Create, Victor L Jardim, Jacques Grall, M.  Beatriz Barros-Barreto, Anaëlle Bizien, Thomas Benoit, Juan C Braga, Juliet Brodie, Thomas Burel, Andrea Cabrito, Guillermo Diaz-Pulido, Patrick Gagnon, Jason M Hall-Spencer, Mathieu Helias, Paulo Antunes Horta, Siddhi Joshi, Nick A Kamenos, Regina Kolzenburg, Erik C Krieger, Erwann Legrand, Tessa M Page, Viviana Peña, Federica Ragazzola, Lina M Rasmusson, Francesco Rendina, Nadine Schubert, João Silva, Frederico T  S Tâmega, Adeline Tauran, Heidi L Burdett

School of Biological and Marine Sciences

Linguistic uncertainty is a prime source of uncertainty pervading ecology and conservation. Coralline algae are a widespread and diverse group of calcifying red macroalgae that underpin coastal ecosystem function and service provision. Recent increasing interest in coralline algae in the scientific literature has revealed a diverse but confusing terminology at organism to habitat scales. Coralline algal research and conservation are international and multidisciplinary, so there are geographic and disciplinary imbalances in research and conservation efforts. To reach consensus and reduce uncertainty, we propose a unified terminology. We review trends in cultural and scientific use of coralline algal terms and propose …


Evaluating The Impact Of School-Based Rebound Therapy On Chest Health In Children And Young People With Neurodisability And Respiratory Issues: A Series Of Single Case Studies, Rachel Knight Lozano, Harriet Shannon, Kayleigh Bell, Julia Melluish, Christopher Morris, Rachel Rapson, Jonathan Marsden Mar 2025

Evaluating The Impact Of School-Based Rebound Therapy On Chest Health In Children And Young People With Neurodisability And Respiratory Issues: A Series Of Single Case Studies, Rachel Knight Lozano, Harriet Shannon, Kayleigh Bell, Julia Melluish, Christopher Morris, Rachel Rapson, Jonathan Marsden

School of Health Professions

PurposeTo evaluate feasibility and impact of an individualised rebound therapy programme on chest health in children with complex neurodisability.Methods and materialsA single-case ABA design was conducted over 18 weeks with five children aged 5–15 years with complex neurodisability. Intervention involved twice weekly rebound therapy for six consecutive weeks in school. Summary outcomes included parent/carer-reported chest health, quality-of-life and clinician-observed motor ability. Serial weekly outcomes included chest health observations, usual care changes, adherence and adverse events. Parents completed a semi-structured interview after follow-up. Quantitative data were analysed descriptively and qualitative data were analysed using thematic analysis.ResultsWithin-case and across-case findings indicated improvement …


The Bionics Bus For Neurology And Neuropsychiatry: Concept Development And Validation, Rohit Shankar Mar 2025

The Bionics Bus For Neurology And Neuropsychiatry: Concept Development And Validation, Rohit Shankar

Peninsula Medical School

Healthcare delivery in the United Kingdom is increasingly becoming a challenging issue where demand is regularly outstripping availability. This is particularly a challenge in neurology and neuropsychiatry, where delays in diagnosis and treatment are leading to worse health and social outcomes. The Darzi report, which focused on three key tenants, has been hailed as the future blueprint for National Health Service (NHS) sustainability and high-quality care delivery. These three tenants are moving from analogue to digital approaches, focusing on prevention and wellbeing, and supporting diagnosis and treatment in communities instead of hospitals. Technological interventions are relevant at all stages of …


Autoantibodies To Apolipoprotein A-I In Hepatitis C Virus Infection: A Role In Disease Progression?, Simon H. Bridge, Sabrina Pagano, John K. Lodge, Isaac T. Shawa, Paula Marin-Crespo, Matthew E. Cramp, David A. Sheridan, Simon D. Taylor-Robinson, Nicolas Vuilleumier, R. Dermot G. Neely, Margaret F. Bassendine Mar 2025

Autoantibodies To Apolipoprotein A-I In Hepatitis C Virus Infection: A Role In Disease Progression?, Simon H. Bridge, Sabrina Pagano, John K. Lodge, Isaac T. Shawa, Paula Marin-Crespo, Matthew E. Cramp, David A. Sheridan, Simon D. Taylor-Robinson, Nicolas Vuilleumier, R. Dermot G. Neely, Margaret F. Bassendine

Peninsula Medical School

Background: Chronic HCV (CHC) infection is associated with autoimmunity. IgG autoantibodies to apolipoprotein A-I (AAA-I) predict all-cause mortality. We evaluated AAA-I in CHC patients and in those who were not viraemic, either because of spontaneous resolution (SR) of infection or HCV clearance following sustained virological response (SVR) after interferon therapy. We limited the study to HCV genotypes 1 and 3, the dominant HCV genotypes circulating in the UK. Methods: Serum samples from 126 CHC patients and 114 nonviraemic individuals (25 SR and 89 SVR) were assayed for AAA-I and lipoproteins. AUC was calculated for AAA-I and HDL-related parameters and used …


The Moving Mandala: Exploring The Pro-Social Effects Of Musical And Non-Musical Synchrony In Children In A Virtual World, Liam Cross, Narcis Pares, Olga Gali, Sena Beste Ercan, Batuhan Sayis, Pamela Heaton, Gray Atherton Mar 2025

The Moving Mandala: Exploring The Pro-Social Effects Of Musical And Non-Musical Synchrony In Children In A Virtual World, Liam Cross, Narcis Pares, Olga Gali, Sena Beste Ercan, Batuhan Sayis, Pamela Heaton, Gray Atherton

School of Psychology

Synchronous movement between individuals has been shown to increase pro-sociality, such as closeness and generosity. To date, synchrony research tests these effects using a variety of movement tasks, including musical and non-musical coordination. However, musical versus non-musical synchrony may have separable pro-social effects. To test this, we had 60 children immersed in an augmented reality space called the 'Moving Mandala' where they moved asynchronously with only visual cues, synchronously with only visual cues or synchronously with musical and visual cues. We then tested for differences in pro-social effects using sharing and proxemics tasks. Results showed that while the synchrony version …


Long Lashes, Mixed Signals: Investigating The Effect Of Eyelash Length On Perceived Health, Attractiveness, And Sexual Receptivity, Farid Pazhoohi Mar 2025

Long Lashes, Mixed Signals: Investigating The Effect Of Eyelash Length On Perceived Health, Attractiveness, And Sexual Receptivity, Farid Pazhoohi

School of Psychology

Eyelashes have evolved as a protective feature for the eyes, offering defense against external dangers such as contamination, excessive evaporation, and shear stress from airflow. They may also serve as indicators of an individual’s health, since various diseases, both congenital and non-congenital, can influence eyelash length. Building on the argument of evolutionary functionality, recent research into human preferences for eyelash length, from an evolutionary perspective, has identified an inverted-U preference pattern across all ethnic groups. However, this research primarily focused on the attractiveness of eyelash length, leaving questions about the alignment of health perceptions and attractiveness and how eyelash length …


An Investigation Of The Acute Effects Of Dance On Heart Rate Variability In People With Parkinson’S, Mirza M F Subhan, Jaspreet Kaur, Sophia Hulbert, Ruth Way Mar 2025

An Investigation Of The Acute Effects Of Dance On Heart Rate Variability In People With Parkinson’S, Mirza M F Subhan, Jaspreet Kaur, Sophia Hulbert, Ruth Way

School of Biomedical Sciences

Background: There is limited research investigating heart rate variability (HRV) in Parkinson’s during dance. The aim of this study was to investigate the effects of dance on HRV in people with Parkinson’s (PwP). Methods: Ten PwP were recruited from a Parkinson’s dance class and completed six sessions; the first half was danced sitting down, while the latter half was standing up. Breathing rate, skin temperature and HRV data were collected and analysed by repeated measures analysis of variance. Results: Analysing all six sections together showed skin temperature (p < 0.001), heart rate (HR; p = 0.029), short-term HRV (SD1; p = 0.025), normalised standard deviation of all the R-R intervals (nSDRR; p = 0.028), and breathing rate (BR; p = 0.001) were significantly different. Conclusions: Significant changes in HR, SD1, nSDRR, BR and skin temperature of PwP occurred during all sections, showing dance improved autonomic function. Further work examining the long-term effects of HRV in a community setting is needed to understand the potential benefits of dance for PwP.


Gamifying Anatomy Outreach: An Underexplored Opportunity, Mikaela L. Stiver, Aamna Naveed, John Chilton, Siobhan M. Moyes Mar 2025

Gamifying Anatomy Outreach: An Underexplored Opportunity, Mikaela L. Stiver, Aamna Naveed, John Chilton, Siobhan M. Moyes

Peninsula Medical School

This article explores the underutilized potential of incorporating gamified approaches into anatomy outreach initiatives. While gamification and game-based learning approaches have been widely adopted in formal educational settings, there is a surprising lack of research on their application for community-based public engagement with anatomy. We emphasize the importance of involving community partners from the outset to co-design gamified outreach activities. A collaborative approach tailors the final products to the needs, preferences, and resources of the target audiences. By actively involving end users, co-design fosters a sense of ownership, relevance, and long-term sustainability for the educational resources. This article also presents …


Hallyu Marketing In Japan: A Configuration Approach To K-Brand Image, Dunya Chen, Jin-Woong Yoo, Saeyeon Roh Mar 2025

Hallyu Marketing In Japan: A Configuration Approach To K-Brand Image, Dunya Chen, Jin-Woong Yoo, Saeyeon Roh

Plymouth Business School

Since cultural community factors shaping the Korean brand (i.e. K-brand) image are rarely discussed, this research identifies the key community elements shaping the K-brand image in Japan where favourable attitudes towards Hallyu (i.e. Korean wave) can occur online. Drawing on the community cluster framework for cultural branding, we employ a configuration approach using Fuzzy-Set Qualitative Comparative Analysis (fsQCA) to uncover the critical cultural community factors and their combinations influencing the K-brand image. Our findings reveal two distinct paths shaping the K-brand image. This paper proposes theoretical and practical insights to strengthen the K-brand image.


The Prevalence Of Weapon Damage: A Proportional Meta-Analysis, Sarah Lane, Erin Mccullough Mar 2025

The Prevalence Of Weapon Damage: A Proportional Meta-Analysis, Sarah Lane, Erin Mccullough

School of Biological and Marine Sciences

Sexually selected weapons are tools that are used in physical fights over mating opportunities. Individuals can face dire fitness consequences if they break their weapon and can no longer fight effectively; however, the costs and consequences of weapon damage have largely been ignored. In this study, the literature was systematically searched to examine the prevalence of weapon damage, and a phylogenetically controlled proportional meta-analysis was conducted to explore factors influencing the patterns of weapon damage across the animal kingdom. A total of 36 suitable studies were identified across 74 species and 13 orders for a total of 82 effect sizes. …


A Comparison Of Physical Characteristics In Different Brands And Staining Techniques In A Brand Of Lissamine Green Strips, Neema Ghorbani-Mojarrad, James S. Wolffsohn, Jennifer P. Craig, Debarun Dutta, Byki Huntjens, Raheel Hussain, Zarghona Khan, Shoaib Raja, Mohammed Ibrahim, Thomas Godfrey, Alison Alderson, Katharine Evans, Mahesh Joshi, Carole Maldonado-Codina, Manbir Nagra, Elidh Martin, Laura Sweeney, Louise Terry, Dean Dunning, Marta Vianya-Estopa Mar 2025

A Comparison Of Physical Characteristics In Different Brands And Staining Techniques In A Brand Of Lissamine Green Strips, Neema Ghorbani-Mojarrad, James S. Wolffsohn, Jennifer P. Craig, Debarun Dutta, Byki Huntjens, Raheel Hussain, Zarghona Khan, Shoaib Raja, Mohammed Ibrahim, Thomas Godfrey, Alison Alderson, Katharine Evans, Mahesh Joshi, Carole Maldonado-Codina, Manbir Nagra, Elidh Martin, Laura Sweeney, Louise Terry, Dean Dunning, Marta Vianya-Estopa

School of Health Professions

Backgrounds/Objectives: The aim of this study was to compare differences in the physical characteristics of lissamine green (LG) strips and the outcomes of using different staining techniques. Methods: Two separate complementary investigations were conducted. Physical study: Differences between four LG strips were evaluated in terms of material, dye concentration, and dye absorption. In vivo study: Bulbar conjunctival staining was compared for four application methods of I-DEW LG strips presented in a randomized order for twenty-two participants: (1) single application 5 s after wetting (also repeated using GreenGlo for comparison), (2) single application using two strips held together, 5 s after …