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Birth Trauma From The Perspective Of Perinatal Counsellors. A Mini Focus Group Study, G Baptie, E Januario, A Norman Jan 2020

Birth Trauma From The Perspective Of Perinatal Counsellors. A Mini Focus Group Study, G Baptie, E Januario, A Norman

School of Psychology

One in five women in the UK develop mental health problems during pregnancy or in the first year after childbirth. ‘Birth trauma’ is a common birth-related mental health issue which stems from perceiving childbirth as a traumatic experience; the term ‘birth trauma’ also encompasses living with and experiencing the accompanying symptoms of trauma after childbirth. A mini focus group study was conducted with two experienced perinatal counsellors to discuss their experiences working with parents struggling with birth trauma. Analysis of the focus group revealed five key themes: the complexity of birth trauma; the power of communication; changes in culture; falling …


An Interdisciplinary Approach To Improving The Quality Of Life In Postural Orthostatic Tachycardia Syndrome: A Case Study, C Turner, D Crocker, J Rhodes, K Nedza, J May Jan 2020

An Interdisciplinary Approach To Improving The Quality Of Life In Postural Orthostatic Tachycardia Syndrome: A Case Study, C Turner, D Crocker, J Rhodes, K Nedza, J May

School of Psychology

No abstract provided.


Children, But Not Great Apes, Respect Ownership, Patricia Kanngiesser, Federico Rossano, Ramona Frickel, Anne Tomm, Michael Tomasello Jan 2020

Children, But Not Great Apes, Respect Ownership, Patricia Kanngiesser, Federico Rossano, Ramona Frickel, Anne Tomm, Michael Tomasello

School of Psychology

Access to and control of resources is a major source of costly conflicts. Animals, under some conditions, respect what others control and use (i.e. possession). Humans not only respect possession of resources, they also respect ownership. Ownership can be viewed as a cooperative arrangement, where individuals inhibit their tendency to take others’ property on the condition that those others will do the same. We investigated to what degree great apes follow this principle, as compared to human children. We conducted two experiments, in which dyads of individuals could access the same food resources. The main test of respect for ownership …


Intentions And Creative Insights: A Reinforcement Learning Study Of Creative Exploration In Problem-Solving, Thomas R. Colin Jan 2020

Intentions And Creative Insights: A Reinforcement Learning Study Of Creative Exploration In Problem-Solving, Thomas R. Colin

School of Engineering, Computing and Mathematics Theses

Insight is perhaps the cognitive phenomenon most closely associated with creativity. People engaged in problem-solving sometimes experience a sudden transformation: they see the problem in a radically different manner, and simultaneously feel with great certainty that they have found the right solution. The change of problem representation is called "restructuring", and the affective changes associated with sudden progress are called the "Aha!" experience. Together, restructuring and the "Aha!" experience characterize insight. Reinforcement Learning is both a theory of biological learning and a subfield of machine learning. In its psychological and neuroscientific guise, it is used to model habit formation, and, …


Investigating The Role Of Tam (Tyro3, Axl And Mertk) Family Receptors In Merlin Deficient Tumours, Foram Dave Jan 2020

Investigating The Role Of Tam (Tyro3, Axl And Mertk) Family Receptors In Merlin Deficient Tumours, Foram Dave

Peninsula Medical School Theses

Mutations in the NF2 gene, which codes for the tumour suppressor Merlin, is responsible for the development of all Neurofibromatosis Type 2 (NF2)-related tumours including schwannomas, meningiomas and ependymomas. These tumours can also occur spontaneously in non-NF2 patients. The only available treatments for this group of tumours are surgery and radiosurgery/radiotherapy. Hence, there is an urgent need for new effective drug-based treatments.TAM (TYRO3, AXL and MERTK) family receptors are involved in tumour development, progression, metastasis and resistance to targeted therapies in several cancers. Our group previously showed overexpression and hyper-activation of all three TAM family receptors and their ligand Gas6 …


Maturity Model For Healthcare Cloud Security, Opeoluwa Ore Akinsanya Jan 2020

Maturity Model For Healthcare Cloud Security, Opeoluwa Ore Akinsanya

School of Engineering, Computing and Mathematics Theses

Management of security across eHealth cloud services is a major organizational challenge that healthcare organizations seek to resolve in order to aid their trusts in cloud and increase the adoption of cloud services in healthcare. The organizational challenges regarding implementations of technical security solutions are the major limiting factors for the adoption of the eHealth cloud. As such, the aim of this research will focus on developing a security maturity model, which will help healthcare organizations to provide a description of the application of their cloud security services, and an assessment and improvement of their cloud security services over time, …


Challenges In Monitoring Mobile Populations - Applying Bayesian Multi-Site Mark-Recapture Abundance Estimation To The Monitoring Of A Highly Mobile Coastal Population Of Bottlenose Dolphins, Simon N. Ingram Jan 2020

Challenges In Monitoring Mobile Populations - Applying Bayesian Multi-Site Mark-Recapture Abundance Estimation To The Monitoring Of A Highly Mobile Coastal Population Of Bottlenose Dolphins, Simon N. Ingram

School of Biological and Marine Sciences

No abstract provided.


Microplastic Exposure Increases Predictability Of Predator Avoidance Strategies In Hermit Crabs, Gerrit B. Nanninga, Cat Horswill, Sarah M. Lane, Andrea Manica, Mark Briffa Jan 2020

Microplastic Exposure Increases Predictability Of Predator Avoidance Strategies In Hermit Crabs, Gerrit B. Nanninga, Cat Horswill, Sarah M. Lane, Andrea Manica, Mark Briffa

School of Biological and Marine Sciences

The contamination of natural systems with plastic debris has become one of the most pressing global environmental issues. Microplastics (MPs) are of particular concern because their ubiquity and small size make them available for ingestion by a range of aquatic biota. MP exposure studies are hence proliferating rapidly but are typically limited to the analyses of population-level responses in toxicity endpoints across treatments. Potential contaminant-induced alterations in behavioural patterns, however, could manifest on numerous levels of variation: at the population level, between individuals and within individuals. Here, we used repeated measures on startle response durations – a risk-avoidance mechanism – …


Effectiveness And Safety Of Opicapone In Parkinson’S Disease Patients With Motor Fluctuations: The Optipark Open-Label Study, Heinz Reichmann, Andrew Lees, José Francisco Rocha, Diogo Magalhães, Patrício Soares-Da-Silva, Camille Carroll Jan 2020

Effectiveness And Safety Of Opicapone In Parkinson’S Disease Patients With Motor Fluctuations: The Optipark Open-Label Study, Heinz Reichmann, Andrew Lees, José Francisco Rocha, Diogo Magalhães, Patrício Soares-Da-Silva, Camille Carroll

Peninsula Medical School

No abstract provided.


A Global Approach To Mapping The Environmental Risk Of Harbours On Aquatic Systems, Paloma F. Valdor, Aina G. Gómez, Peter Steinberg, Edwina Tanner, Antony M. Knights, Rochelle D. Seitz, Laura Airoldi, Louise B. Firth, Christos Arvanitidis, Massimo Ponti, Eva Chatzinikolaou, Paul R. Brooks, Tasman P. Crowe, Alison Smith, Gonzalo Méndez, Aida Ovejero, Abilio Soares-Gomes, John A. Burt, Catriona Macleod, José A. Juanes Jan 2020

A Global Approach To Mapping The Environmental Risk Of Harbours On Aquatic Systems, Paloma F. Valdor, Aina G. Gómez, Peter Steinberg, Edwina Tanner, Antony M. Knights, Rochelle D. Seitz, Laura Airoldi, Louise B. Firth, Christos Arvanitidis, Massimo Ponti, Eva Chatzinikolaou, Paul R. Brooks, Tasman P. Crowe, Alison Smith, Gonzalo Méndez, Aida Ovejero, Abilio Soares-Gomes, John A. Burt, Catriona Macleod, José A. Juanes

School of Biological and Marine Sciences

The goal of this paper is to propose a screening method for assessing the environmental risk to aquatic systems in harbours worldwide. A semi-quantitative method is based on environmental pressures, environmental conditions and societal response. The method is flexible enough to be applied to 15 harbours globally distributed through a multinational test using standardised and homogenised open data that can be obtained for any port worldwide. The method emerges as a useful approach towards the foundation of a global environmental risk atlas of harbours that should guide the harbour sector to develop a more globally informed strategy of sustainable development.


Novel Insights Into The Marine Phase And River Fidelity Of Anadromous Twaite Shad Alosa Fallax In The Uk And Ireland, Peter Davies, Robert J. Britton, Andrew D. Nunn, Jamie R. Dodd, Charles Crundwell, Randolph Velterop, Niall Ó’Maoiléidigh, Ross O'Neill, Emma V. Sheehan, Thomas Stamp, Jonathan D. Bolland Jan 2020

Novel Insights Into The Marine Phase And River Fidelity Of Anadromous Twaite Shad Alosa Fallax In The Uk And Ireland, Peter Davies, Robert J. Britton, Andrew D. Nunn, Jamie R. Dodd, Charles Crundwell, Randolph Velterop, Niall Ó’Maoiléidigh, Ross O'Neill, Emma V. Sheehan, Thomas Stamp, Jonathan D. Bolland

School of Biological and Marine Sciences

No abstract provided.


Photo- And Autoxidation Of Unsaturated Algal Lipids In The Marine Environment: An Overview Of Processes, Their Potential Tracers, And Limitations, Jean François Rontani, Simon T. Belt Jan 2020

Photo- And Autoxidation Of Unsaturated Algal Lipids In The Marine Environment: An Overview Of Processes, Their Potential Tracers, And Limitations, Jean François Rontani, Simon T. Belt

School of Geography, Earth and Environmental Sciences

No abstract provided.


Atomic Spectrometry Update: Review Of Advances In Elemental Speciation, Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. Tyson Jan 2020

Atomic Spectrometry Update: Review Of Advances In Elemental Speciation, Robert Clough, Chris F. Harrington, Steve J. Hill, Yolanda Madrid, Julian F. Tyson

School of Geography, Earth and Environmental Sciences

This review covers advances in elemental speciation by a range of coupled techniques, including HPLC-ICP-MS, HPLC-HG-AFS and GC-ICP-MS.


Effects Of Chlorhexidine Mouthwash On The Oral Microbiome, Raul Bescos, Ann Ashworth, Craig Clarke, Zoe L. Brookes, Louise Belfield, Ana Rodiles, Patricia Casas-Agustench, Garry Farnham, Luke Liddle, Mia Burleigh, Desley White, Chris Easton, Mary Hickson Jan 2020

Effects Of Chlorhexidine Mouthwash On The Oral Microbiome, Raul Bescos, Ann Ashworth, Craig Clarke, Zoe L. Brookes, Louise Belfield, Ana Rodiles, Patricia Casas-Agustench, Garry Farnham, Luke Liddle, Mia Burleigh, Desley White, Chris Easton, Mary Hickson

Peninsula Dental School

Following a single blind, cross-over and non-randomized design we investigated the effect of 7-day use of chlorhexidine (CHX) mouthwash on the salivary microbiome as well as several saliva and plasma biomarkers in 36 healthy individuals. They rinsed their mouth (for 1 min) twice a day for seven days with a placebo mouthwash and then repeated this protocol with CHX mouthwash for a further seven days. Saliva and blood samples were taken at the end of each treatment to analyse the abundance and diversity of oral bacteria, and pH, lactate, glucose, nitrate and nitrite concentrations. CHX significantly increased the abundance of …


Dna Preserved In Jetsam Whale Ambergris, Ruairidh Macleod, Mikkel Holger S. Sinding, Morten Tange Olsen, Matthew J. Collins, Steven J. Rowland Jan 2020

Dna Preserved In Jetsam Whale Ambergris, Ruairidh Macleod, Mikkel Holger S. Sinding, Morten Tange Olsen, Matthew J. Collins, Steven J. Rowland

More Faculty of Science and Engineering Research

Jetsam ambergris, found on beaches worldwide, has always been assumed to originate as a natural product of sperm whales (Physeteroidea). However, only indirect evidence has ever been produced for this, such as the presence of whale prey remains in ambergris. Here, we extracted and analysed DNA sequences from jetsam ambergris from beaches in New Zealand and Sri Lanka, and sequences from ambergris of a sperm whale beached in The Netherlands. The lipid-rich composition of ambergris facilitated high preservation-quality of endogenous DNA, upon which we performed shotgun Illumina sequencing. Alignment of mitochondrial and nuclear genome sequences with open-access reference data for …


Schneiderian Membrane Thickness Variation Following Endodontic Procedures: A Retrospective Cone Beam Computed Tomography Study, Den Munckhof T Van, S Patel, G Koller, E Berkhout, F Mannocci, F Foschi Jan 2020

Schneiderian Membrane Thickness Variation Following Endodontic Procedures: A Retrospective Cone Beam Computed Tomography Study, Den Munckhof T Van, S Patel, G Koller, E Berkhout, F Mannocci, F Foschi

Peninsula Dental School

Background To assess the change of the Schneider membrane thickness measured by CBCT before and after root canal treatment, retreatment and pulp capping procedures. Methods This retrospective study was conducted on CBCT scans of a patient population of Guy’s Hospital NHS Foundation Trust, London. Three groups of patients were studied: Group 1 consisted of patients referred for primary endodontic treatment; Group 2 for endodontic retreatment; Group 3 for indirect pulp capping procedures (serving as a control group). Follow up scans were carried out 1 year after treatment. Measurements were carried out on CBCT scans and data were analysed statistically by …


Modulation Of Oral Microbiota: A New Frontier In Exercise Supplementation, Raul Bescos, Zoe L.S. Brookes, Louise A. Belfield, Manuel Fernandez-Sanjurjo, Patricia Casas-Agustench Jan 2020

Modulation Of Oral Microbiota: A New Frontier In Exercise Supplementation, Raul Bescos, Zoe L.S. Brookes, Louise A. Belfield, Manuel Fernandez-Sanjurjo, Patricia Casas-Agustench

Peninsula Dental School

No abstract provided.


Weathering And Persistence Of Plastic In The Marine Environment: Lessons From Lego, Andrew Turner, Rob Arnold, Tracey Williams Jan 2020

Weathering And Persistence Of Plastic In The Marine Environment: Lessons From Lego, Andrew Turner, Rob Arnold, Tracey Williams

School of Geography, Earth and Environmental Sciences

No abstract provided.


Mobilisation Of Antimony From Microplastics Added To Coastal Sediment, Elanor James, Andrew Turner Jan 2020

Mobilisation Of Antimony From Microplastics Added To Coastal Sediment, Elanor James, Andrew Turner

School of Geography, Earth and Environmental Sciences

No abstract provided.


The Influence Of Additives On The Fate Of Plastics In The Marine Environment, Exemplified With Barium Sulphate, Andrew Turner, Montserrat Filella Jan 2020

The Influence Of Additives On The Fate Of Plastics In The Marine Environment, Exemplified With Barium Sulphate, Andrew Turner, Montserrat Filella

School of Geography, Earth and Environmental Sciences

No abstract provided.


Characterising A Human Endogenous Retrovirus(Herv)-Derived Tumour-Associated Antigen: Enriched Rna-Seq Analysis Of Herv-K(Hml-2) In Mantle Cell Lymphoma Cell Lines, Witold Tatkiewicz, James Dickie, Franchesca Bedford, Alexander Jones, Mark Atkin, Michele Kiernan, Emmanuel Atangana Maze, Bora Agit, Garry Farnham, Alexander Kanapin, Robert Belshaw Jan 2020

Characterising A Human Endogenous Retrovirus(Herv)-Derived Tumour-Associated Antigen: Enriched Rna-Seq Analysis Of Herv-K(Hml-2) In Mantle Cell Lymphoma Cell Lines, Witold Tatkiewicz, James Dickie, Franchesca Bedford, Alexander Jones, Mark Atkin, Michele Kiernan, Emmanuel Atangana Maze, Bora Agit, Garry Farnham, Alexander Kanapin, Robert Belshaw

School of Biomedical Sciences

Background The cell-surface attachment protein (Env) of the HERV-K(HML-2) lineage of endogenous retroviruses is a potentially attractive tumour-associated antigen for anti-cancer immunotherapy. The human genome contains around 100 integrated copies (called proviruses or loci) of the HERV-K(HML-2) virus and we argue that it is important for therapy development to know which and how many of these contribute to protein expression, and how this varies across tissues. We measured relative provirus expression in HERV-K(HML-2), using enriched RNA-Seq analysis with both short- and long-read sequencing, in three Mantle Cell Lymphoma cell lines (JVM2, Granta519 and REC1). We also confirmed expression of the …


A Survey Investigating The Combination And Number Of Imus On The Human Body Used For Detecting Activities And Human Tracking, Olaf Reich, Erik Hubner, Bogdan Ghita, Matthias F. Wagner, Jorg Schafer Jan 2020

A Survey Investigating The Combination And Number Of Imus On The Human Body Used For Detecting Activities And Human Tracking, Olaf Reich, Erik Hubner, Bogdan Ghita, Matthias F. Wagner, Jorg Schafer

School of Engineering, Computing and Mathematics

No abstract provided.


Homogenization And Polarization Of The Seasonal Water Discharge Of Global Rivers In Response To Climatic And Anthropogenic Effects, Yuanfang Chai, Yao Yue, Lin Zhang, Chiyuan Miao, Alistair G.L. Borthwick, Boyuan Zhu, Yitian Li, A. J. Dolman Jan 2020

Homogenization And Polarization Of The Seasonal Water Discharge Of Global Rivers In Response To Climatic And Anthropogenic Effects, Yuanfang Chai, Yao Yue, Lin Zhang, Chiyuan Miao, Alistair G.L. Borthwick, Boyuan Zhu, Yitian Li, A. J. Dolman

School of Engineering, Computing and Mathematics

No abstract provided.


Determination, Occurrence, And Treatment Of Saccharin In Water: A Review, Lina Pang, Alistair G.L. Borthwick, Efthalia Chatzisymeon Jan 2020

Determination, Occurrence, And Treatment Of Saccharin In Water: A Review, Lina Pang, Alistair G.L. Borthwick, Efthalia Chatzisymeon

School of Engineering, Computing and Mathematics

No abstract provided.


Dynamic Flood Topographies In The Terai Region Of Nepal, E. H. Dingle, M. J. Creed, H. D. Sinclair, D. Gautam, N. Gourmelen, A. G.L. Borthwick, M. Attal Jan 2020

Dynamic Flood Topographies In The Terai Region Of Nepal, E. H. Dingle, M. J. Creed, H. D. Sinclair, D. Gautam, N. Gourmelen, A. G.L. Borthwick, M. Attal

School of Engineering, Computing and Mathematics

AbstractFlood hazard maps used to inform and build resilience in remote communities in the Terai region of southern Nepal are based on outdated and static digital elevation models (DEMs), which do not reflect dynamic river configuration or hydrology. Episodic changes in river course, sediment dynamics, and the distribution of flow down large bifurcation nodes can modify the extent of flooding in this region, but these processes are rarely considered in flood hazard assessment. Here, we develop a 2D hydrodynamic flood model of the Karnali River in the Terai region of west Nepal. A number of scenarios are tested examining different …


Intention Recognition Of Elbow Joint Based On Semg Using Adaptive Fuzzy Neural Network, Y Liu, Chunxu Li, Zhaowei Teng, K Liu, Gang Wang, Zhongbo Sun Jan 2020

Intention Recognition Of Elbow Joint Based On Semg Using Adaptive Fuzzy Neural Network, Y Liu, Chunxu Li, Zhaowei Teng, K Liu, Gang Wang, Zhongbo Sun

School of Engineering, Computing and Mathematics

No abstract provided.


Conversations In A Crowded Room: An Assessment Of The Contribution Of Historical Research To Criminology, Henry Yeomans, David Churchill, Iain Channing Jan 2020

Conversations In A Crowded Room: An Assessment Of The Contribution Of Historical Research To Criminology, Henry Yeomans, David Churchill, Iain Channing

School of Law, Humanities and Social Sciences

The relationship between history and social science generally, as well as history and criminology specifically, has long been considered problematic. But, since the likes of Burke (1992) and King (1999) spoke of a ‘dialogue of the deaf’, crime history has rapidly expanded and, more latterly, historical criminology has begun to emerge. This article reappraises the relationship of the subject areas by considering the impact that historical research has had on criminology. Although the impact is found to be somewhat patchy, the article identifies positive signs within the two fields that might point towards a more mutually-enriching future.


Trade Agreements And The Risks For The Nursing Workforce, Nursing Practice And Public Health: A Scoping Review, D Kidgell, D Hills, D Griffiths, R Endacott Jan 2020

Trade Agreements And The Risks For The Nursing Workforce, Nursing Practice And Public Health: A Scoping Review, D Kidgell, D Hills, D Griffiths, R Endacott

School of Nursing and Midwifery

No abstract provided.


Harnessing The Power Of Machine Learning In Dementia Informatics Research: Issues, Opportunities, And Challenges, Gavin Tsang, Xianghua Xie, Shang Ming Zhou Jan 2020

Harnessing The Power Of Machine Learning In Dementia Informatics Research: Issues, Opportunities, And Challenges, Gavin Tsang, Xianghua Xie, Shang Ming Zhou

School of Nursing and Midwifery

No abstract provided.


Arsenic Speciation And Its Dna Fractionation In The Rice Plant Oryza Sativa, Me Foulkes, Ba Sadee, Sj Hill Jan 2020

Arsenic Speciation And Its Dna Fractionation In The Rice Plant Oryza Sativa, Me Foulkes, Ba Sadee, Sj Hill

School of Geography, Earth and Environmental Sciences

The transport of arsenic from soil through to edible crop is important when assessing the potential health risks from a food source.