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Full-Text Articles in Entire DC Network
Comparing The Effect Of Marine Aquarium Salts And Sodium Chloride On Vicia Faba Stress Response, Bethany Smerdon
Comparing The Effect Of Marine Aquarium Salts And Sodium Chloride On Vicia Faba Stress Response, Bethany Smerdon
The Plymouth Student Scientist
Soil salinity is a major abiotic stressor limiting agricultural productivity. Many salt stress studies rely solely on sodium chloride (NaCl) solutions, despite not accurately representing natural saline conditions. This study investigated the stress response of Vicia faba to NaCl and marine aquarium salt (MAS) solutions to assess the impact of a more complex ionic composition on plant physiology. Plants were cultivated in a controlled greenhouse and treated with either NaCl, MAS, or rainwater (control) for up to 55 days. Growth parameters, water status, proline accumulation, chlorophyll content, and root nodule weight were measured to evaluate stress responses. The results indicate …
Evaluating The Impacts Of The Invasive Macrophyte, Crassula Helmsii, On Macroinvertebrate Assemblages At Small Spatial Scales In Lentic Ecosystems, Keivan Rakhshani
Evaluating The Impacts Of The Invasive Macrophyte, Crassula Helmsii, On Macroinvertebrate Assemblages At Small Spatial Scales In Lentic Ecosystems, Keivan Rakhshani
The Plymouth Student Scientist
Freshwater ecosystems cover only three percent of the Earth’s surface yet support approximately ten percent of global biodiversity. These systems play a crucial role in maintaining native biodiversity across spatial and temporal scales but are increasingly threatened by anthropogenic stressors, including habitat modification, pollution, and biological invasions. The introduction of non-native macrophytes can fundamentally alter community structure by modifying habitat complexity, resource availability, and competitive interactions. This study assesses the impact of the invasive macrophyte Crassula helmsii on macroinvertebrate assemblages at small spatial scales within partially invaded ponds in Dartmoor National Park, southwest England. Three ponds with varying degrees of …
Assessing Jasmonic Acid Seed Priming In Brassica Napus: Impacts On Aphid Herbivory Resistance And Seedling Fitness Trade-Offs, Daisy Stradling
Assessing Jasmonic Acid Seed Priming In Brassica Napus: Impacts On Aphid Herbivory Resistance And Seedling Fitness Trade-Offs, Daisy Stradling
The Plymouth Student Scientist
Jasmonic acid (JA) is a key phytohormone involved in plant defence, offering a potential sustainable alternative to conventional chemical pesticides. While JA seed priming has been explored as a strategy to enhance herbivore resistance in certain plant families, its potential fitness trade-offs remain poorly understood. This study investigates the effects of JA seed priming on Brassica napus (oilseed rape), a key agricultural crop, focusing on seedling fitness and resistance to Brevicoryne brassicae (mealy cabbage aphid), a major agricultural pest. To assess potential fitness trade-offs, seeds were primed with 75 µM JA, and multiple seedling fitness parameters were measured. Germination monitoring …
Investigating Deception-Related Moral Conflict Using Electroencephalography (Eeg) Hyperscanning, Madie Ades
Investigating Deception-Related Moral Conflict Using Electroencephalography (Eeg) Hyperscanning, Madie Ades
The Plymouth Student Scientist
Amplitudes of the early Bereitschaftspotential (BP) and deceptive behaviour have been theorised to be modulated by moral conflict experienced when making deceptive decisions, as the decision to lie can depend upon our moral perceptions of what is right and wrong (Panasiti et al., 2014). However, most Electroencephalography (EEG) deception paradigms lack ecological validity by utilising instructed lying and failing to incorporate genuine social interaction (Ganis & Keenan, 2009) and therefore may fail to elicit genuine moral conflict. The present study combined hyperscanning EEG with a competitive two-player social game, where participants freely chose to respond accurately or deceptively for …
Threshold Sites Of Encounter: Dialogic (Place) Making To Enable Cross-Cultural Community Development—Lessons From Tuti Island, Khartoum, Sudan, Ioana Popovici, Robert Brown
Threshold Sites Of Encounter: Dialogic (Place) Making To Enable Cross-Cultural Community Development—Lessons From Tuti Island, Khartoum, Sudan, Ioana Popovici, Robert Brown
School of Art, Design and Architecture
This text explores a possibility for extending our thinking on enacting dialogical placemaking and its potential to contribute to cross-cultural exchange through co-joining making and place as threshold sites of encounter. Advancing our knowledge and practice of dialogical placemaking and cross-cultural interaction is significant owing to the increasing presence of cultural differences, and with it economic, environmental, and social disparities, in an ever-increasingly globalized world. To advance this intention, this text will, through qualitative research, critically reflect upon the experience of a postgraduate Design Studio project based around the regeneration of an urban community situated in Khartoum, Sudan. Preliminary conclusions …
Dose-Dependent Benefits Of Dietary Yeast Cell Wall Supplementation On The Growth Performance And Stress Resilience Of The European Seabass (Dicentrarchus Labrax), Camille Houdelet, Ana Teresa Goncalves, Jorge Dias, Mark Rawling, Eric Leclercq
Dose-Dependent Benefits Of Dietary Yeast Cell Wall Supplementation On The Growth Performance And Stress Resilience Of The European Seabass (Dicentrarchus Labrax), Camille Houdelet, Ana Teresa Goncalves, Jorge Dias, Mark Rawling, Eric Leclercq
School of Biological and Marine Sciences
Preventive health management is central to modern aquaculture practices, within which functional feed additives are a key tool to optimising fish robustness and disease resilience. Despite being well documented, only few studies have assessed the dose–effect of graded levels of S. cerevisiae yeast cell wall (YCW) on fish performance and mucosal barrier immunity. A 9-week trial was conducted to assess the impact of graded levels of YCW on the performance and mucosal barriers of the European seabass under period: (1) non-challenge (43 days) then (2) with an applied husbandry stressors (20 days) in the form of high stocking density, low …
The Science Of Gamification: Reimagining Biomedical Education Through Gamified Learning, Laura Bowater, Michael Dillon
The Science Of Gamification: Reimagining Biomedical Education Through Gamified Learning, Laura Bowater, Michael Dillon
Peninsula Medical School
No abstract provided.
Rewilding Gender: Toward Relational Understandings Of ‘The Wild’, Kim Ward
Rewilding Gender: Toward Relational Understandings Of ‘The Wild’, Kim Ward
School of Geography, Earth and Environmental Sciences
This commentary reframes gender and rewilding through a relational understanding of wildness. Moving beyond a binary lens of ‘the wild’, it examines how gendered relations shape rewilding's material, emotional, and epistemic dimensions. Centring relational wildness exposes how rewilding challenges masculine imaginaries of control and ownership while opening space for more equitable multispecies relations.
Non-Invasive Ultrasonic Neuromodulation Of The Human Nucleus Accumbens Impacts Reward Sensitivity, Siti N Yaakub, John Eraifej, Nadège Bault, Mathilde Lojkiewiez, Elouan Bellec, Jamie Roberts, Noah S Philip, Amir Puyan Divanbeighi Zand, Alexander L Green, Matthew F S Rushworth, Elsa F Fouragnan
Non-Invasive Ultrasonic Neuromodulation Of The Human Nucleus Accumbens Impacts Reward Sensitivity, Siti N Yaakub, John Eraifej, Nadège Bault, Mathilde Lojkiewiez, Elouan Bellec, Jamie Roberts, Noah S Philip, Amir Puyan Divanbeighi Zand, Alexander L Green, Matthew F S Rushworth, Elsa F Fouragnan
School of Psychology
Precisely neuromodulating deep brain regions could bring transformative advancements in both neuroscience and treatment. We demonstrate that non-invasive transcranial ultrasound stimulation (TUS) can selectively modulate deep brain activity and affect learning and decision making, comparable to deep brain stimulation (DBS). We tested whether TUS could causally influence neural and behavioural responses by targeting the nucleus accumbens (NAcc) using a reinforcement learning task. Twenty-six healthy adults completed a within-subject TUS-fMRI experiment with three conditions: TUS to the NAcc, dorsal anterior cingulate cortex (dACC), or Sham. After TUS, participants performed a probabilistic learning task during fMRI. TUS-NAcc altered BOLD responses to reward …
Variation In Corneal Biomechanical Properties Following Continuous Cross-Linking Treatment, Daniela Oehring, Chenhao Zhao, Xinyu Yao, Yewei Zhao, Fangjun Bao, Ahmed Elsheikh, Hongjiang Wu, Jiahui Zon, Xuanya Tong, Lan Yang, Xiaofei Zhou, Ying Li, Yanjie Shen, Yufeng Ye, Shihao Chen, Jia Qu, Qinmei Wang
Variation In Corneal Biomechanical Properties Following Continuous Cross-Linking Treatment, Daniela Oehring, Chenhao Zhao, Xinyu Yao, Yewei Zhao, Fangjun Bao, Ahmed Elsheikh, Hongjiang Wu, Jiahui Zon, Xuanya Tong, Lan Yang, Xiaofei Zhou, Ying Li, Yanjie Shen, Yufeng Ye, Shihao Chen, Jia Qu, Qinmei Wang
School of Health Professions
BackgroundThis retrospective study aimed to evaluate the ecacy of transepithelial accelerated corneal cross-linking when applied separately (transEpi ACXL) or combined with phototherapeutic keratectomy (transPTK ACXL) in keratoconic eyes using biomechanical parameters.MethodsThe study included eyes with progressive keratoconus treated with either continuous transEpi ACXL or transPTK ACXL with 6 months of follow-up. The following parameters were assessed preoperatively and 6 months postoperatively: biomechanically corrected intraocular pressure (bIOP), maximum and mean keratometry (Kmax and Km), minimum and central corneal thickness (MCT and CCT), corneal coma, best-corrected visual acuity (BCVA), deformation amplitude ratio at the apex and 2 mm nasal/temporal (DAR2), integrated inverse …
Thinning Antarctic Glaciers Expose High-Altitude Nunataks Delivering More Bioavailable Iron To The Southern Ocean, Kate Winter, John Woodward, Stuart A. Dunning, James R. Jordan, Joseph A. Graly, Matthew J. Westoby, Sian F. Henley, Robert Raiswell
Thinning Antarctic Glaciers Expose High-Altitude Nunataks Delivering More Bioavailable Iron To The Southern Ocean, Kate Winter, John Woodward, Stuart A. Dunning, James R. Jordan, Joseph A. Graly, Matthew J. Westoby, Sian F. Henley, Robert Raiswell
School of Geography, Earth and Environmental Sciences
Glacial systems entrain and transfer sediment, rich in essential nutrients, from continental sources to the ocean, where they are released by meltwater. In the Southern Ocean, primary producers are limited by the availability of micronutrients, like iron (Fe), so any increase in continental sediment supply could enhance primary productivity and subsequent drawdown of atmospheric CO2. Here we provide a systematic account of labile Fe concentrations in Antarctic continental sediments. Ferrihydrite and crystalline Fe (oxyhydr)oxides were extracted from 27 Antarctic samples collected from nunataks, lateral moraines and blue ice areas in the Sør Rondane Mountains, East Antarctica. We report …
The Mcgill Diverse Face Database: 92 Complex Mental States Across Socially Perceived Racial Categories, Gunnar Schmidtmann
The Mcgill Diverse Face Database: 92 Complex Mental States Across Socially Perceived Racial Categories, Gunnar Schmidtmann
School of Health Professions
Theory of Mind (ToM)—the ability to infer others’ mental states—is fundamental to social cognition. Social categorization, the grouping of individuals into in-group or out-group categories, shapes these inferences. These processes co-occur during facial perception, with recent research suggesting both shared neurocognitive mechanisms and modulation of ToM by social category cues. However, existing tools for studying the impact of racial diversity on social cognition are limited: some databases prioritize racial representation but restrict stimuli to the six basic emotions, while others broaden mental state diversity but lack diversity in social appearance.Here we introduce the McGill Diverse Face Database, a validated set …
Spatial And Temporal Variation In Wave Overtopping Across A Coastal Structure Based On One Year Of Field Observations, Jennifer Brown, Gerd Masselink, Margaret Yelland, Christopher Stokes, Timothy Poate, Robin Pascal, David Jones, John Walk, Christopher Cardwell, Barry Martin, Peter Ganderton, Julie Gregory, Ruth Adams, Joseff Saunders
Spatial And Temporal Variation In Wave Overtopping Across A Coastal Structure Based On One Year Of Field Observations, Jennifer Brown, Gerd Masselink, Margaret Yelland, Christopher Stokes, Timothy Poate, Robin Pascal, David Jones, John Walk, Christopher Cardwell, Barry Martin, Peter Ganderton, Julie Gregory, Ruth Adams, Joseff Saunders
School of Biological and Marine Sciences
Coastal managers worldwide must prepare for changes in annual wave overtopping events due to climate change and sea-level rise. Research often assesses overtopping discharges by extreme events at a sea wall crest, typically using data from physical models or empirical rules based on scaled experiments. Here, we analyse a unique 1-year field dataset of coastal wave overtopping, from SW England, to determine the number of individual waves, regardless of their size, overtopping two locations across a coastal structure. The coastal conditions causing the most frequent overtopping differ from those driving it landward, complicating hazard communications for multiuse infrastructure. These data …
Cultural Innovation Can Increase And Maintain Biodiversity: A Case Study From Medieval Europe, Adam Spitzig, Manfred Rösch, Jessie Woodbridge, Martin Bauch, Piotr Guzowski, Peter Erhart, Ralph Fyfe, Elena Marinova, Adam Izdebski
Cultural Innovation Can Increase And Maintain Biodiversity: A Case Study From Medieval Europe, Adam Spitzig, Manfred Rösch, Jessie Woodbridge, Martin Bauch, Piotr Guzowski, Peter Erhart, Ralph Fyfe, Elena Marinova, Adam Izdebski
School of Geography, Earth and Environmental Sciences
Numerous research efforts have used paleoecological data to reconstruct past biodiversity in Europe. In these projects, researchers have identified increases in biodiversity over the Holocene and hinted at a positive correlation with human population. These are important findings but are not easily translated into effective biodiversity conservation and restoration policy. We argue that, in order to better inform policymaking, studies of past biodiversity dynamics should include analyses of contemporaneous cultural phenomena in order to identify and describe specific anthropogenic drivers of past biodiversity changes. We present an example here, a case study from the Lake Constance region (southwestern Germany), one …
Unveiling Novel Bladder Cancer Associations From Multicentred Primary And Secondary Care Electronic Health Records By Machine Learning: A Case-Control Study, Xu Wang, Andrea Preston, Jonathan Aning, Shang-Ming Zhou
Unveiling Novel Bladder Cancer Associations From Multicentred Primary And Secondary Care Electronic Health Records By Machine Learning: A Case-Control Study, Xu Wang, Andrea Preston, Jonathan Aning, Shang-Ming Zhou
School of Nursing and Midwifery
ObjectiveThe rising incidence and mortality in bladder cancer (BC) underscore the importance of identifying asscociated features. Current reliance on haematuria as a primary indicator for BC proves inadequate. While mining electronic health records (EHRs) offer potential of identifying BC-related signals, traditional data-driven methods struggle with high-dimensional datasets. This study aims to uncover novel BC-associated clinical signals by developing Parsimony-driven cAtegory-balaNced binary Signal extractor for Primary Care EHRs (PanSPICE) tailored to extremely high-dimensional data linked from multi-centres.MethodsWe collected BC cases and control patients (n = 64,884) linked at patient-level from Welsh nationwide databases, yielding 48,261 features in primary care settings. The …
In Vitro And In Vivo Evaluation Of Autochthonous Probiotics And Their Effects On The Mucosal Health Of Nile Tilapia (Oreochromis Niloticus), Sherilyn T. Abarra, Sahya Maulu, Sheu G. Odu-Onikosi, Taofik A. Momoh, Benjamin Eynon, Matthew Emery, Mark Rawling, Daniel L. Merrifield
In Vitro And In Vivo Evaluation Of Autochthonous Probiotics And Their Effects On The Mucosal Health Of Nile Tilapia (Oreochromis Niloticus), Sherilyn T. Abarra, Sahya Maulu, Sheu G. Odu-Onikosi, Taofik A. Momoh, Benjamin Eynon, Matthew Emery, Mark Rawling, Daniel L. Merrifield
School of Biological and Marine Sciences
The host microbiome is a promising source of probiotics for aquaculture species including Nile tilapia. In this study, the probiotic potential of autochthonous bacterial isolates from Nile tilapia and carp mid-intestines were screened in vitro. Two isolates (C61 and T70), closely related to Bacillus subtilis, exhibited antagonistic activity against multiple pathogen species and demonstrated multiple digestive enzyme activities. Their antagonistic activity in Aeromonas hydrophila assays remained even under simulated intestinal juice (SIJ) exposure. Subsequently, C61 (PT1) and T70 (PT2) were added to experimental diets at log 7 CFU/g of diet, and fed to Nile tilapia (5.32 ± 0.12 g) for …
Artificial Light At Night Alters Seaweed Reproductive Phenology, Emma Moyse, Louise Firth, Tim Smyth, Thomas Davies
Artificial Light At Night Alters Seaweed Reproductive Phenology, Emma Moyse, Louise Firth, Tim Smyth, Thomas Davies
School of Biological and Marine Sciences
Artificial light at night (ALAN) is a growing, globally prevalent environmental stressor. It is known to disrupt biological processes across taxa and biomes, including reproductive phenology in terrestrial plants, but its potential to alter reproductive timings in marine macroalgae remains unexplored. We used reflectance spectrometry to quantitatively assess changes in receptacle ripeness of three fucoid macroalgae species at four field sites along an ALAN gradient in Plymouth Sound, UK over a six-month period. At sites with elevated ALAN (measured using Sky Quality Meters, range 16.15–18.76 mag arcsec −2, equivalent to 3.75 × 10 −2–3.38 × 10 −3 cd/m …
Integrating Heritage Assets Into Peatland Restoration: Finding, Assessing And Valuing The Palaeoenvironmental Archive, Heather Davies, Ralph Fyfe
Integrating Heritage Assets Into Peatland Restoration: Finding, Assessing And Valuing The Palaeoenvironmental Archive, Heather Davies, Ralph Fyfe
School of Geography, Earth and Environmental Sciences
Peatland restoration projects aim to improve the delivery of ecosystem services. Cultural heritage and Historic Environment assets are usually identified as co-beneficiaries of restoration but are not commonly well-integrated at the planning or design stages. This paper considers the heritage value of upland peatlands and methods for integrating these values in ecosystem services approaches. Taking Exmoor National Park as a case study, an extensive walkover survey identified 119 small mires and assessed their cultural heritage asset potential. Many were not previously recognised as part of the Historic Environment potential of the upland. A novel valuation system based on proximity of …
Dendritic Inhibition Effects In Memory Retrieval Of A Neuromorphic Microcircuit Model Of The Rat Hippocampus, Nikolaos Andreakos, Vassilis Cutsuridis
Dendritic Inhibition Effects In Memory Retrieval Of A Neuromorphic Microcircuit Model Of The Rat Hippocampus, Nikolaos Andreakos, Vassilis Cutsuridis
School of Engineering, Computing and Mathematics
Background: Studies have shown that input comparison in the hippocampus between the Schaffer collateral (SC) input in apical dendrites and the perforant path (PP) input in the apical tufts dramatically changes the activity of pyramidal cells (PCs). Equally, dendritic inhibition was shown to control PC activity by minimizing the depolarizing signals in their dendritic trees, controlling the synaptic integration time window, and ensuring temporal firing precision. Objectives: We computationally investigated the diverse roles of inhibitory synapses on the PC dendritic arbors of a CA1 microcircuit model in mnemonic retrieval during the co-occurrence of SC and PP inputs. Results: Our study …
Phanerozoic Paleoenvironmental And Paleoclimatic Evolution In Svalbard, Aleksandra Smyrak-Sikora, Peter Betlem, Victoria S. Engelschiøn, William J. Foster, Sten Andreas Grundvåg, Mads E. Jelby, Morgan T. Jones, Grace E. Shephard, Kasia K. Śliwińska, Madeleine L. Vickers, Valentin Zuchuat, Lars Eivind Augland, Jan Inge Faleide, Jennifer M. Galloway, William Helland-Hansen, Maria A. Jensen, Erik P. Johannessen, Maayke Koevoets, Denise Kulhanek, Gareth S. Lord, Tereza Mosociova, Snorre Olaussen, Sverre Planke, Gregory D. Price, Lars Stemmerik, Kim Senger
Phanerozoic Paleoenvironmental And Paleoclimatic Evolution In Svalbard, Aleksandra Smyrak-Sikora, Peter Betlem, Victoria S. Engelschiøn, William J. Foster, Sten Andreas Grundvåg, Mads E. Jelby, Morgan T. Jones, Grace E. Shephard, Kasia K. Śliwińska, Madeleine L. Vickers, Valentin Zuchuat, Lars Eivind Augland, Jan Inge Faleide, Jennifer M. Galloway, William Helland-Hansen, Maria A. Jensen, Erik P. Johannessen, Maayke Koevoets, Denise Kulhanek, Gareth S. Lord, Tereza Mosociova, Snorre Olaussen, Sverre Planke, Gregory D. Price, Lars Stemmerik, Kim Senger
School of Geography, Earth and Environmental Sciences
Sedimentary rocks can provide information about the Earth paleoenvironment and are studied extensively to understand the causes and consequences of global climate changes in deep time. They facilitate long-time perspectives that constrain climate models and provide analogues for how Earth systems may respond to, and recover from, intervals of profound environmental change, including projected anthropogenic change. The Norwegian Svalbard archipelago offers an extensive Phanerozoic stratigraphic record that reflects the geological evolution of the northern flanks of continental assemblages that include Laurentia, Eurasia, and Pangea. Svalbard’s Phanerozoic sedimentary and paleoclimatic archive is controlled largely by Svalbard’s overall northward plate-tectonic motion from …
Image Data From: Prototyping Deep Transfer Learning Classification Of Holographic Plankton Imagery, Kairan Cursons, Pierre Hélaouët, William H Wilson, Rob Camp, Alex Nimmo Smith
Image Data From: Prototyping Deep Transfer Learning Classification Of Holographic Plankton Imagery, Kairan Cursons, Pierre Hélaouët, William H Wilson, Rob Camp, Alex Nimmo Smith
Faculty of Science and Engineering Datasets
Data used for the training and evaluation of Convolution Neural Networks (CNN) for the accompanying paper. Paper Abstract: The Continuous Plankton Recorder (CPR) is an autonomous plankton sampling platform towed by volunteer vessels along their standard routes, facilitating long-term, monthly sampling across extensive geographic areas. The integrated Continuous Plankton Recorder (iCPR) enhances the traditional CPR survey with new data by utilising the CPR sampler as a platform to deploy new technologies in modular self-powered packages, including high-resolution digital plankton imaging through a bespoke holographic camera. This paper presents the development of a computational pipeline for the preprocessing and classification of …
Borrowed Competence: Socially Extending The Mind To Extend Digital Practices, Cordelia R. Stewart, Sheau-Fen (Crystal) Yap, Krzysztof Kubacki
Borrowed Competence: Socially Extending The Mind To Extend Digital Practices, Cordelia R. Stewart, Sheau-Fen (Crystal) Yap, Krzysztof Kubacki
More Faculty of Arts, Humanities and Business Research
This study extends current understanding of digital competence by exploring alternative skill sets harnessed by digitally disadvantaged groups that enable their practices to continue. By combining practice theory with the socially extended mind framework, we address the research question: What forms of offline competence support the integration of digital practices among a disadvantaged consumer group, and how do these competences influence the cohesion and continuity of their practices? Through an ethnography of a ‘Street Church’ community, we demonstrate how different forms of offline social interaction (i.e., sequential, synchronised, substitutive) and group culture
function as valuable resources for guiding digital practices, …
Impact Of Growth Conditions On The Abundance And Diversity Of Cultivable Bacteria Recovered From Pheronema Carpenteri And Investigation Of Their Antimicrobial Potential, Jazmin Conway, Grant G January, Katie J Muddiman, Rosemary Dorrington, Kerry L Howell, Mathew Upton
Impact Of Growth Conditions On The Abundance And Diversity Of Cultivable Bacteria Recovered From Pheronema Carpenteri And Investigation Of Their Antimicrobial Potential, Jazmin Conway, Grant G January, Katie J Muddiman, Rosemary Dorrington, Kerry L Howell, Mathew Upton
School of Biomedical Sciences
The deep sea is a largely unexplored extreme environment supporting a diverse biological community adapted to low temperatures and high pressures. Such environments support microbial life that may be a source of novel antibiotics and other drugs. Whilst this is often the case, many species with bioactive capabilities may be missed with traditional culturing methods. In this study, a total of 16 different concentrations and types of media were employed, to culture 389 bacterial isolates using Dilution to Extinction methods and Actinobacteria Directed Cultivation techniques. This generated 72 (18.6%) isolates with narrow and broad-spectrum activity against ESKAPE pathogens including Escherichia …
Comparative Risk Of End-Stage Renal Disease, Myocardial Infarction And Stroke In Young And Older Onset Diabetes In Uk Biobank, Debasish Kar, Mariam Molokhia, Anthony Wierzbicki, Ania Koziell, Richard Byng, Stuart Spicer, Nicolas Farina, Jonathan Pinkney, Soon Song, Bedowra Zabeen, Shubharthi Kar, Jitendra Jonnagaddala, Siaw-Teng Liaw, Aya El-Wazir, Mintu Nath, Moien Khan, Aziz Sheikh, Simon De Lusignan
Comparative Risk Of End-Stage Renal Disease, Myocardial Infarction And Stroke In Young And Older Onset Diabetes In Uk Biobank, Debasish Kar, Mariam Molokhia, Anthony Wierzbicki, Ania Koziell, Richard Byng, Stuart Spicer, Nicolas Farina, Jonathan Pinkney, Soon Song, Bedowra Zabeen, Shubharthi Kar, Jitendra Jonnagaddala, Siaw-Teng Liaw, Aya El-Wazir, Mintu Nath, Moien Khan, Aziz Sheikh, Simon De Lusignan
Peninsula Medical School
In recent years, coinciding with the increasing incidence of type 2 diabetes mellitus (T2DM) in children and adolescents, the global prevalence of diabetic kidney disease (DKD) and end-stage renal disease (ESRD) are rising year on year. In contrast, the mortality and morbidity due to cardiovascular disease (CVD) and stroke in people with diabetes have been declining. The precise cause of the disparate vascular outcomes in diabetes remains unexplored. To elucidate the relationship, we conducted a retrospective cohort study on the UK Biobank data. In our study, the exposure variables were the age of diabetes and hypertension diagnosis, while the outcome …
Emotional Hypervigilance: Development Of A New Questionnaire And Examining The Importance To Posttraumatic Quality Of Life., Alison Bacon, Alyson Norman
Emotional Hypervigilance: Development Of A New Questionnaire And Examining The Importance To Posttraumatic Quality Of Life., Alison Bacon, Alyson Norman
School of Psychology
Objective: Hypervigilance is a symptom of posttraumatic stress disorder usually defined in terms of behaviours such as environment scanning and planning escape routes. The objective of Study 1 was to develop a new measure to assess the extent to which individuals employ a specifically emotional form of hypervigilance. The aim of Study 2 was to investigate whether emotional hypervigilance is associated with posttraumatic quality of life in addition to the known effects of symptoms and experiential avoidance. Method: Study 1 presents the development and initial testing (N = 275) of the Emotional Vigilance and Awareness Questionnaire (EVAQ). In Study 2, …
Can Dietary Supplements Support Muscle Function And Physical Activity? A Narrative Review, Louise Brough, Gail Rees, Lylah Drummond-Clarke, Jennifer E. Mccallum, Elisabeth Taylor, Oleksii Kozhevnikov, Steven Walker
Can Dietary Supplements Support Muscle Function And Physical Activity? A Narrative Review, Louise Brough, Gail Rees, Lylah Drummond-Clarke, Jennifer E. Mccallum, Elisabeth Taylor, Oleksii Kozhevnikov, Steven Walker
School of Biomedical Sciences
Dietary supplementation is commonly used by athletes to gain muscle mass, enhance performance, and improve recovery. Most adults engage in insufficient physical activity. Yet healthy muscles are also critical for activities of daily living (ADLs), maintaining a good quality of life and positive ageing. There is growing interest in whether dietary supplementation is of value, particularly among subgroups such as the occasionally active, the ill and elderly, and peri- and menopausal women. By focusing on function, performance, mass and strength, ADLs, exercise-induced muscle damage and delayed onset muscle soreness, this review sought to examine muscle health through a nutritional lens. …
A Collaborative Approach To Marine Species Tracking: Insights From The Fish Intel Acoustic Telemetry Network, Alice E. Hall, Tom Stamp, Peter Davies, Mathieu Woillez, Martial Laurans, Marine Gonse, Lydie I.E. Couturier, Olivier Blanpain, Katia Frangoudes, Emmanuelle Quillérou, Eider Graner, Jan Reubens, Carlotta Muñiz, Lucy A. Hawkes, Matthew J. Witt, Thomas W. Horton, Tom Hooper, Ricky Pender, Erwin Quemeneur, Mewen Abjean, Xavier Tetard, Pascal Provost, Silvana Birchenough, Jean Luc Solandt, Colin Trundle, Amy Y. Cartwright, Sian Rees, Ronan Conlon, Shion E.A. Reynell, Ben Ciotti
A Collaborative Approach To Marine Species Tracking: Insights From The Fish Intel Acoustic Telemetry Network, Alice E. Hall, Tom Stamp, Peter Davies, Mathieu Woillez, Martial Laurans, Marine Gonse, Lydie I.E. Couturier, Olivier Blanpain, Katia Frangoudes, Emmanuelle Quillérou, Eider Graner, Jan Reubens, Carlotta Muñiz, Lucy A. Hawkes, Matthew J. Witt, Thomas W. Horton, Tom Hooper, Ricky Pender, Erwin Quemeneur, Mewen Abjean, Xavier Tetard, Pascal Provost, Silvana Birchenough, Jean Luc Solandt, Colin Trundle, Amy Y. Cartwright, Sian Rees, Ronan Conlon, Shion E.A. Reynell, Ben Ciotti
School of Biological and Marine Sciences
Acoustic telemetry offers valuable insights into species' spatial and temporal movement patterns, helping to understand habitat use, behaviour and migration timings. The Fish Intel Network established a collaborative cross-English Channel acoustic telemetry network to track multiple species over small and large spatial scales. This network was designed in close alliance with local fishers to incorporate essential local ecological knowledge of target species and habitats, gathered through interviews and workshops. To date, 254 acoustic receivers have been deployed, and 874 animals have been tagged across the Channel. Six species were tracked for this study: European bass (Dicentrarchus labrax), pollack (Pollachius pollachius), …
Impact Of Macroporosity On The Transesterification Of Triglycerides Over Mgo/Sba-15, Thomas A. Bryant, Lois Damptey, Mark A. Isaacs, Christopher M.A. Parlett, Lee J. Durndell, Marta Granollers Mesa, Georgios Kyriakou, Karen Wilson, Adam F. Lee
Impact Of Macroporosity On The Transesterification Of Triglycerides Over Mgo/Sba-15, Thomas A. Bryant, Lois Damptey, Mark A. Isaacs, Christopher M.A. Parlett, Lee J. Durndell, Marta Granollers Mesa, Georgios Kyriakou, Karen Wilson, Adam F. Lee
School of Geography, Earth and Environmental Sciences
Biofuels are critical drop-in replacement energy sources to support the decarbonisation of hard-to-abate sectors such as aviation and marine shipping. Transesterification of non-edible oils is a well-established route to biodiesel as a versatile liquid transport fuel, but is challenging to scale using existing homogeneous liquid base catalysts. In this work, we report the synthesis, characterisation, and application of silica-supported MgO solid base catalysts for triglyceride transesterification with methanol and highlight the impact of silica pore structure on performance. True liquid crystal templating enables the one-pot synthesis of mesoporous MgO/SBA-15 catalysts with variable Mg content, or hierarchical macroporous–mesoporous MgO/SBA-15 analogues through …
Survival And Recovery Of Three Shark Species In North-East Atlantic Recreational Fisheries, Francesco Garzon, Ghalia Abel, Ian Burrett, Owen Exeter, Lucy A. Hawkes, Thomas Horton, Mario Lambrette, Alex Plaster, David Righton, Hannah Rudd, Jessica Rudd, Bryce Stewart, Simon Thomas, James Thorburn, Paul Whittaker, Matthew J. Witt
Survival And Recovery Of Three Shark Species In North-East Atlantic Recreational Fisheries, Francesco Garzon, Ghalia Abel, Ian Burrett, Owen Exeter, Lucy A. Hawkes, Thomas Horton, Mario Lambrette, Alex Plaster, David Righton, Hannah Rudd, Jessica Rudd, Bryce Stewart, Simon Thomas, James Thorburn, Paul Whittaker, Matthew J. Witt
School of Biological and Marine Sciences
Understanding how sharks respond to catch and release (C&R) recreational fisheries is an important requirement for effective management. Post-release survival and recovery in recreational fisheries can be species- and setting-dependent. Nevertheless, no study on sharks has been conducted in European recreational fisheries, despite their popularity as target. This study presents the first example of biologging to assess C&R effects on blue sharks (Prionace glauca), porbeagle sharks (Lamna nasus) and tope sharks (Galeorhinus galeus) in the UK. Pop-up satellite archival tags (n = 23 blue shark, 20 porbeagle shark, 26 tope shark) revealed high (94.7–96.2%) survival rates in all three species, …
Itrusst Consensus On Biophysical Safety For Transcranial Ultrasound Stimulation, Jean François Aubry, David Attali, Mark E. Schafer, Elsa Fouragnan, Charles F. Caskey, Robert Chen, Ghazaleh Darmani, Ellen J. Bubrick, Jérôme Sallet, Christopher R. Butler, Charlotte J. Stagg, Miriam C. Klein-Flügge, Seung Schik Yoo, Christy K. Holland, Bradley Treeby, Eleanor Martin, Lennart Verhagen, Kim Butts Pauly
Itrusst Consensus On Biophysical Safety For Transcranial Ultrasound Stimulation, Jean François Aubry, David Attali, Mark E. Schafer, Elsa Fouragnan, Charles F. Caskey, Robert Chen, Ghazaleh Darmani, Ellen J. Bubrick, Jérôme Sallet, Christopher R. Butler, Charlotte J. Stagg, Miriam C. Klein-Flügge, Seung Schik Yoo, Christy K. Holland, Bradley Treeby, Eleanor Martin, Lennart Verhagen, Kim Butts Pauly
School of Psychology
Transcranial ultrasound stimulation (TUS) is an emerging technology for non-invasive brain stimulation. The International Transcranial Ultrasonic Stimulation Safety and Standards consortium (ITRUSST) has established consensus on considerations for nonsignificant biophysical risk of TUS, drawing upon the literature and established regulations for biomedical devices. Here, we assume the application of TUS to individuals without contraindications, compromised thermoregulation, vascular vulnerabilities, or administered ultrasound contrast agents. In this context, we present a concise yet comprehensive set of levels for nonsignificant risks of TUS application. For mechanical effects, it is non-significant risk if the mechanical index (MI) or the mechanical index for transcranial application …