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A Pilot Study Assessing The Oral Microbiome In Women Of Menopausal Age: Do Oral Nitrate–Reducing Bacteria Play A Role?, Katie Muddiman, Amazon Doble, Abish Stephen, Raul Bescos Garcia, Charlotte Illsley, Tomas Nicholas, Sally Hanks, Lisa Du Toit, Zoe Brookes
A Pilot Study Assessing The Oral Microbiome In Women Of Menopausal Age: Do Oral Nitrate–Reducing Bacteria Play A Role?, Katie Muddiman, Amazon Doble, Abish Stephen, Raul Bescos Garcia, Charlotte Illsley, Tomas Nicholas, Sally Hanks, Lisa Du Toit, Zoe Brookes
Peninsula Dental School
Introduction The links between oral health and female ageing are poorly understood, but many changes occur in the oral cavity of menopausal women that affect quality of life, and few current oral health interventions consider gender as part of their approach. The aim of this pilot study was to test the hypothesis that the oral microbiome and microenvironment change during female ageing and are thus worthy of further consideration both experimentally and clinically. Methods This observational pilot study retrospectively assessed women aged 18 to 89 years (n = 60) attending a UK primary care dental school facility for blood pressure …
Investigating The Determinants Of Fight Dynamics In The Minotaur Beetle Typhaeus Typhoeus, Amy Bromley
Investigating The Determinants Of Fight Dynamics In The Minotaur Beetle Typhaeus Typhoeus, Amy Bromley
School of Biological and Marine Sciences Theses
It is widely accepted that the main determinants of contest outcome are resource value, residency status, and resource holding potential, with each of these playing an important role in determining contest behaviour. Examples of resource holding potential are morphological traits such as body size and weaponry. Animals that possess weaponry can exhibit different morphotypes, such as size difference in horns, which can lead to differences in contest behaviour, with larger morphotypes engaging in head-to-head combat, while smaller morphotypes can avoid combat altogether. One such species that possess weapons in the form of horns and engages in physical combat, is the …
Investigating The Potential Utilisation Of Black Soldier Fly (Hermetia Illucens) As An Alternative Protein Source In Tilapia And Carp Feed, Sahya Maulu
School of Biological and Marine Sciences Theses
Three experimental trials were conducted to evaluate defatted black soldier fly (BSF; Hermetia illucens) larvae meal and BSF frass as alternative protein ingredients. Defatted BSF larvae meal was tested in diets for both Nile tilapia (Oreochromis niloticus) and mirror carp (Cyprinus carpio), whereas BSF frass was assessed only in Nile tilapia.In the first experiment, dietary inclusion of 20% and 40% BSF meal, replacing mainly soybean meal (SBM) and corn gluten meal (CGM), was evaluated in Nile tilapia over 5 weeks. BSF improved growth and feed utilisation in a dose-dependent manner, increased posterior intestinal fold length, muscularis thickness, and goblet cell …
Physiological And Morphological Responses To Drought Stress In Different Cultivation Environments In Wild Type And Aba-Deficient Barley, Chloe Betts
School of Biological and Marine Sciences Theses
Global food security is increasingly threatened by the effects of climate change. Of the environmental factors affected by climate change, drought is one of the most critical for plant survival and reproduction, shaping plant morphology and physiology and therefore crop productivity. Although the effects of drought on plants are widely studied, studies are often conducted in controlled greenhouse or laboratory conditions rather than more realistic field-like conditions. This is justified by the lower costs, convenience, and ability to disentangle the effects of different factors in more controlled conditions. This thesis explores the effect of the same watering limitations in different …
Plastic Pollution: Investigating Environmental Pathways And Critically Evaluating Interventions, Florence Parker-Jurd
Plastic Pollution: Investigating Environmental Pathways And Critically Evaluating Interventions, Florence Parker-Jurd
School of Biological and Marine Sciences Theses
Plastics are lightweight, versatile, and durable materials used in the manufacture of a wide range of products. Innovation in the early 1950’s facilitated a dramatic reduction in production costs with the potential to mass produce inexpensive convenience items intended for single use applications. As a consequence, plastic production has grown exponentially over the last 75 years, and a throw away culture of single use has become deeply engrained in modern society. Plastic production exceeds 450 million tonne/yr, substantially exceeding our capacity to manage associated waste resulting in pollution accumulating in every compartment of the natural environment. While plastic pollution has …
Coral Reef Fishes In Different Hard And Soft Coral-Dominated Reef Habitats, Ana Coelho
Coral Reef Fishes In Different Hard And Soft Coral-Dominated Reef Habitats, Ana Coelho
School of Biological and Marine Sciences Theses
Understanding how fish communities respond to different coral habitats is essential for predicting the future resilience of coral reef ecosystems. This study tested whether fish assemblages differ between hard and soft coral–dominated reef plots and among coral genera. We predicted higher fish abundance and more frequent benthic interactions in hard coral plots, and genus-specific differences in community composition, behaviour, and time spent within plots. This study examined fish species diversity, richness, abundance, behaviour, and the time spent in coral habitats. The analysis encompassed seven coral genera in an Indo-Pacific reef system. Twenty 2 × 2 m reef areas, each dominated …
Effects Of Salinity, Region, Site, And Cohort On Growth Traits Of The Black Mangrove, Avicennia Germinans, Bekki Foster
Effects Of Salinity, Region, Site, And Cohort On Growth Traits Of The Black Mangrove, Avicennia Germinans, Bekki Foster
School of Biological and Marine Sciences Theses
Mangroves are trees that are adapted to grow in saline or brackish environments, typically, in estuarine and coastal zones in tropical and subtropical areas. Their root complexity supports marine biodiversity by providing habitat and nursery grounds for fishes and their canopies serve as roosting and breeding sites for avian species. Additionally, roots facilitate nutrient capture through epibiont communities and trap suspended sediments, enhancing stability against high-energy weather and contributing to vertical accretion, potentially mitigating sea level rise. This study aimed to investigate how such factors as salinity, provenance, and genetic background, affect the above and below ground morphological traits of …
Influence Of Ecological Transitions On The Evolution Of Circadian And Light Detection Genes In Squamates, Isobel Sleep
Influence Of Ecological Transitions On The Evolution Of Circadian And Light Detection Genes In Squamates, Isobel Sleep
School of Biological and Marine Sciences Theses
Circadian rhythms are self-sustaining, endogenous processes that align behaviour and physiology with daily environmental cycles. Rhythms are regulated by conserved genes forming transcriptional feedback loops and are entrained by environmental cues (e.g., light). Circadian systems are well studied in model organisms, their molecular evolution in squamates (lizards and snakes) remains less understood. Squamates represent the most species-rich reptile group with extensive ecological and sensory diversity, exhibiting multiple independent transitions across ecological niches, including repeated shifts into low-light environments (e.g., nocturnality, fossoriality), making them ideal for examining circadian and light-associated gene evolution. This study investigates how ecological transitions have influenced the …
Large-Scale Coastal Dynamics: New Incites From Lidar And Satellite Remote Sensing, Aikaterini Konstantinou
Large-Scale Coastal Dynamics: New Incites From Lidar And Satellite Remote Sensing, Aikaterini Konstantinou
School of Biological and Marine Sciences Theses
This thesis leverages remote sensing methods to advance understanding of shoreline morphodynamics from storm to decadal timescales, focusing on three interrelated objectives. First, regional patterns and timescales of beach recovery following the extreme 2013/14 winter were quantified using bi-annual LiDAR and RTK-GNSS surveys of 23 south-west England sites. Recovery trajectories exhibited consistent patterns aligned with pre-existing storm response classifications, demonstrating that both storm response and post-storm recovery can be classified into four groups governed by intrinsic geomorphological and hydrodynamic controls. Almost 90% of sites had recovered at least 75% of lost sediment within three years, while some fully exposed beaches …
Trialing A Novel Method Of Skin Mucus Sampling To Measure Stress And Reproductive Steroid Hormones In Mobula Species Mobula Alfredi And Mobula Munkiana, Bethany Faulkner
Trialing A Novel Method Of Skin Mucus Sampling To Measure Stress And Reproductive Steroid Hormones In Mobula Species Mobula Alfredi And Mobula Munkiana, Bethany Faulkner
School of Biological and Marine Sciences Theses
Anthropogenic pressures, exacerbated by exceptionally slow population growth, have led to all mobulid species being listed on the IUCN Red List. Understanding stress and reproductive physiology is essential for improving mobulid conservation strategies. However, few studies have investigated the hormonal processes that underlie stress responses and reproductive physiology in mobulids. Studies on fish species have identified positive correlations between steroid hormone concentrations in blood and skin mucus, the collection of the latter being a much less invasive technique. This pilot study examined the feasibility of using skin mucus as a non-invasive matrix for detecting steroid hormones in two mobulid species. …
Impacts Of Microplastics In A Changing Agri-Environment, Riley Kent
Impacts Of Microplastics In A Changing Agri-Environment, Riley Kent
School of Biological and Marine Sciences Theses
Microplastics are increasingly recognized as persistent contaminants in terrestrial ecosystems, yet their impacts on plant performance remain poorly understood under realistic environmental conditions. In natural and agricultural systems, plants rarely encounter contaminants in isolation, instead experiencing multiple interacting stressors. The work presented in this thesis investigated how soil microplastics influence plant growth and physiology both independently and in combination with freshwater flooding, a climate-relevant stressor associated with increased storm activity and shifts in precipitation patterns. Using white clover (Trifolium repens) as a model agronomic legume across multiple cultivars, the study examined how polymer identity, plant genotype, and environmental context interact …
From Public To Policy How Jellyfish Data And Citizen Science Can Be Used For Biodiversity Management, John Terenzini
From Public To Policy How Jellyfish Data And Citizen Science Can Be Used For Biodiversity Management, John Terenzini
School of Biological and Marine Sciences Theses
Long term biodiversity data is necessary for detecting biological and ecological changes to marine ecosystems. The data can inform marine policy, yet data are often lacking for some species and traditional data collection approaches can be logistically challenging and expensive. Jellyfish are one taxon for which data are lacking, and data collection can be challenging due to their life history traits and the inherent challenges of marine research. This research aims to provide evidence for the importance of monitoring jellyfish, demonstrate the effectiveness of citizen science for monitoring jellyfish, and examine how jellyfish monitoring data can inform international frameworks. The …
Does In-Bed Cycling Delivered Within 48 Hours Of Mechanical Ventilation, Reduce The Occurrence Of Delirium In Critically Ill Patients: A Mixed-Methods Feasibility Randomised Controlled Trial Protocol, Jacqueline Bennion, Mark Hudson, Mary Hickson, Victoria Allgar, Bridie Kent, David Mcwilliams, Daniel Martin
Does In-Bed Cycling Delivered Within 48 Hours Of Mechanical Ventilation, Reduce The Occurrence Of Delirium In Critically Ill Patients: A Mixed-Methods Feasibility Randomised Controlled Trial Protocol, Jacqueline Bennion, Mark Hudson, Mary Hickson, Victoria Allgar, Bridie Kent, David Mcwilliams, Daniel Martin
Peninsula Medical School
Background: Delirium is a severe neuropsychiatric clinical state presenting as an acute onset of cognitive deficits. Patients receiving invasive mechanical ventilation (IMV), have the highest incidence (50%–80%) of delirium amongst patients admitted to intensive care units. Preliminary data indicates that early mobilisation is associated with reduced delirium in critically ill patients. However, definitive evidence is lacking. Current practice varies due to many barriers to patients, who require IMV, receiving early mobilisation interventions. In-bed cycling may address some of these barriers. This research aims to evaluate the feasibility and acceptability of early in-bed cycling to reduce delirium in critically ill patients. …
The Effectiveness Of Digital Therapeutics Intervention In Oral Anticoagulation Management: A Systematic Review And Meta-Analysis, Jiayue Guo, Lili You, Lu Liu, Xitong Jiao, Debasish Kar, Jitendra Jonnagaddala
The Effectiveness Of Digital Therapeutics Intervention In Oral Anticoagulation Management: A Systematic Review And Meta-Analysis, Jiayue Guo, Lili You, Lu Liu, Xitong Jiao, Debasish Kar, Jitendra Jonnagaddala
Peninsula Medical School
Objective: To summarize the key intervention characteristics and evaluate the effectivenessand safety of digital therapeutics (DTx) in patients receiving oral anticoagulation, witheffectiveness evaluated using time in therapeutic range (TTR), thromboembolic events (TEE),and mortality, and safety evaluated based on bleeding events.Patients and Methods: We searched PubMed, Embase, Web of Science, and the CochraneLibrary from inception to June 20, 2025, and identified ten randomized controlled trialsinvolving 7,237 patients. The criteria required studies to assess software-based DTxsupporting anticoagulation management and report effectiveness or safety outcomes. Studyquality was evaluated using the Grading of Recommendations, Assessment, Development,and Evaluation (GRADE) framework, and random-effects models were applied.Results: …
Children And Adults Across 15 Countries Believe In Human Uniqueness Of Mind: A Cross-Cultural Investigation Of Cross-Species Mind Perception, Karri Neldner, Luke Maurits, Magie Junker, Lara Abbas, Nayrouz Abbas, Arianna Abis, Federica Amici, Bernardo Arroyo-Garcia, Negar Asghari, Giovanna Barragán Pardo, Zhen Zhang, Junior Peña Chumacero, Ardain Dzabatou, Dustin Eirdosh, Susan Hanisch, Tom Herrnsdorf, Tom Hovehne, Alicia Junker, Patricia Kanngiesser, Felipe Villa Larens, Safaa Mahmoud, Sandra Masaquiza, Iino Masato, Risma Illa Maulany, Tongtong Meng, Kardelen Mutlu, Putu Oka Ngakan, Ebru Peközer, Ljubica Petrović, Mirella Christy Rehatalanit
Children And Adults Across 15 Countries Believe In Human Uniqueness Of Mind: A Cross-Cultural Investigation Of Cross-Species Mind Perception, Karri Neldner, Luke Maurits, Magie Junker, Lara Abbas, Nayrouz Abbas, Arianna Abis, Federica Amici, Bernardo Arroyo-Garcia, Negar Asghari, Giovanna Barragán Pardo, Zhen Zhang, Junior Peña Chumacero, Ardain Dzabatou, Dustin Eirdosh, Susan Hanisch, Tom Herrnsdorf, Tom Hovehne, Alicia Junker, Patricia Kanngiesser, Felipe Villa Larens, Safaa Mahmoud, Sandra Masaquiza, Iino Masato, Risma Illa Maulany, Tongtong Meng, Kardelen Mutlu, Putu Oka Ngakan, Ebru Peközer, Ljubica Petrović, Mirella Christy Rehatalanit
School of Psychology
The way humans relate to other animals is fundamentally shaped by whether we perceive ourselves as unique, with feelings and thoughts not shared by other animals. How beliefs about animals’ ability to feel and think develop across cultures remains largely unexplored. We asked children and adolescents (4–17 years, N = 1025) and adults (N = 190) from 33 urban and rural communities across 15 countries whether animals have thoughts or feelings (judgments of presence), and whether those thoughts or feelings are human-like (judgments of similarity). Bayesian analyses revealed that participants generally ascribed non-human animals the ability for thoughts and feelings. …
Integrating Neuroscience And Social Psychology In Researching Interprofessional Education: The Inspire Framework, Kimberley Schenke, Pamela Rae, Jaysan Charlesford, Phil Gee
Integrating Neuroscience And Social Psychology In Researching Interprofessional Education: The Inspire Framework, Kimberley Schenke, Pamela Rae, Jaysan Charlesford, Phil Gee
School of Psychology
There is an increasing focus on the importance of interprofessional education as an integral part of health and social care training. However, the fundamental psychological processes underlying successful interprofessional education are not well understood. Here we propose a single framework, Integrating Neuroscience and Social Psychology In Researching Interprofessional Education (INSPIRE), grounded in evidence from social psychology and neuroscience that could be used to generate testable hypotheses to inform the design, development and evaluation of interprofessional education. The application of this framework offers a novel, scientifically grounded approach to improving the learning outcomes of interprofessional education and provides a foundation for …
Adherence And Compliance With Exercise Training In Progressive Multiple Sclerosis: Rates And Correlates From The Cogex Trial, Cogex Research Team, Robert W. Motl, Andrew Argie, Roberto S. Hernandez, Brian M. Sandroff, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Maria A. Rocca, Amber Salter, Anthony Feinstein
Adherence And Compliance With Exercise Training In Progressive Multiple Sclerosis: Rates And Correlates From The Cogex Trial, Cogex Research Team, Robert W. Motl, Andrew Argie, Roberto S. Hernandez, Brian M. Sandroff, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Maria A. Rocca, Amber Salter, Anthony Feinstein
School of Health Professions
Background: There is limited understanding of adherence and compliance rates for exercise training(ET) in people with progressive multiple sclerosis(PMS).Objectives: This secondary, exploratory data analysis examined rates of adherence and compliance for continuous, moderate intensity training and high-intensity intervaltraining(HIIT) and possible correlates among people with PMS from the CogEx trial.Methods: CogEx was a multi-site, multi-arm, randomized, double-blinded, and shamcontrolled trial undertaken by 11 sites in six di8erent countries. Participants(N=311) wererandomized into one of four conditions with di8erent combinations of ET and cognitive rehabilitation, including respective sham conditions, delivered twice weekly over 12 weeks.The analysis focused on adherence and compliance rates and …
Assessing The Application Of Optical-Photothermal Infrared Spectroscopy For Single-Grain Chemical Palynology, Laura Scoble, Hao Meng, Simon J. Ussher, Mark F. Fitzsimons, Lauren Ansell, Mustafa Kansiz, Billy Simmonds, Nick Stone, Ralph M. Fyfe
Assessing The Application Of Optical-Photothermal Infrared Spectroscopy For Single-Grain Chemical Palynology, Laura Scoble, Hao Meng, Simon J. Ussher, Mark F. Fitzsimons, Lauren Ansell, Mustafa Kansiz, Billy Simmonds, Nick Stone, Ralph M. Fyfe
School of Geography, Earth and Environmental Sciences
Single-grain pollen analysis is essential for advancing chemical palynology, which classifies morphologically similar taxa based on taxon-specific pollen and sporopollenin chemistry. Fourier-Transform Infrared (FT-IR) spectroscopy and microspectroscopy (μFT-IR) are widely used to differentiate morphologically similar grains but face limitations from Mie scattering and coarse spatial resolution. Here, we present the first application of Optical-PhotoThermal Infrared (O-PTIR) spectroscopy to chemically treated single pollen grains, using Molinia caerulea as a model taxon to fully test and evaluate the technical capabilities and limitations of this technique. O-PTIR achieves sub-micron “super-resolution” infrared spectroscopy through non-contact, non-destructive measurements by exploiting the photothermal effect. O-PTIR spectra …
A Conceptual Framework For Improving The Oral Health Of Children With Disabilities, Shiamaa Al-Mashhadani
A Conceptual Framework For Improving The Oral Health Of Children With Disabilities, Shiamaa Al-Mashhadani
Peninsula Dental School Theses
AbstractTitle: A Conceptual Framework for Improving the Oral Health of Children with DisabilitiesShiamaa Shihab Al-MashhadaniIntroduction:The effect of good oral health contributes to improving general health, well-being, and quality of life. Children with disabilities are more likely to develop oral diseases than the general population. They are disproportionately affected by dental diseases such as high dental caries, periodontal disease prevalence, missing teeth, and malocclusion. There are many challenges that children with disabilities and their carers experience regarding oral health, including access to dental care, availability of preventive interventions, oral health literacy, and education.This study aims to understand the personal experiences and …
The Molecular Effects Of Microwave Irradiation Upon Antibiotic-Resistant Bacterial Pathogens, Alistair White
The Molecular Effects Of Microwave Irradiation Upon Antibiotic-Resistant Bacterial Pathogens, Alistair White
Peninsula Dental School Theses
IntroductionAntimicrobial resistance is a global health crisis due to the emergence and spread of multidrug-resistant bacteria, driven by poor antibiotic stewardship, particularly in low to middle income countries where antibiotics can be bought over the counter. Currently, the molecular diagnosis of infections and genomic DNA extraction are both hindered by several factors including, expense, time, technical expertise, and the requirement of a laboratory-based setting. This makes it difficult to extract genomic material at point-of-care preventing the use of rapid molecular methods for the detection of antibiotic resistant genes. Thus, the gold standard for determining the appropriate antibiotics to treat infections …
Antigypsyism: Foundations Of An Ideology Of Hatred Towards Roma, Fernando Ruiz Molina, Zoë James
Antigypsyism: Foundations Of An Ideology Of Hatred Towards Roma, Fernando Ruiz Molina, Zoë James
School of Law, Humanities and Social Sciences
Roma communities represent the largest ethnic minority in Europe (European Parliamentary Research Service, 2021), dating their presence from the fourteenth century onwards (Council of Europe [CoE], 2012a; CoE n.d.-a; End, 2012).¹Accord-ing to the Council of Europe, it is estimated that the population of Roma citizens living currently in Europe is around 10 to 12 million (CoE, 2012a). Despite their long-standing presence in European countries, Roma are hated within their own countries. From Eastern to Western Europe, animosity towards Roma centres on public acceptance of stereotypes of their criminality and lifestyles, leading to this minority group experiencing the most bias-motivated crime …
Errors And Misconceptions In Mathematics Teacher Retraining: An Investigation Of Subject Knowledge Enhancement Course Results, Gabor Szalontai
Errors And Misconceptions In Mathematics Teacher Retraining: An Investigation Of Subject Knowledge Enhancement Course Results, Gabor Szalontai
School of Law, Humanities and Social Sciences Theses
This thesis investigates the subject knowledge capabilities and deficiencies of teachers who wished to enter or return to secondary mathematics teaching and took part in the Subject Knowledge Enhancement Plus programme. It focuses on the proportions, types and causes of their mistakes, as well as their potential for development and the possibility of increasing their awareness of errors.The study uses recorded responses of 1602 participants from the online assessment of the courses, which ran across England. The assessment, covering the entire secondary curriculum and consisting of 643 questions, provided an interactive, multiple-attempt design allowing the investigation of the participants’ results …
Integrative Analysis Of Differentially Regulated Proteins In Meningioma, Maryam Shah
Integrative Analysis Of Differentially Regulated Proteins In Meningioma, Maryam Shah
Peninsula Medical School Theses
Background: Meningiomas are the most common primary intracranial tumours that arise from arachnoid cap cells of the meninges and dura border cells. These tumours share a unique epigenetic and genomic landscape. The most common epigenetic event in meningiomas is the loss of chromosome 22q. About 50% of meningiomas harbour mutations in the NF2 gene that resides on chromosome 22 and codes for a protein named “Merlin”. Moreover, frequent mutations can be observed in genes including AKT1, KLF4, TRAF7, SMO, and PIK3CA. Based on mutations, meningiomas can be divided into different genomic subgroups that express unique proteomic profiles. …
Stimuli Development To Measure Parafoveal Contrast Sensitivity In Age-Related Macular Degeneration At Varying Luminance Levels, Joao Alhada Lourenco
Stimuli Development To Measure Parafoveal Contrast Sensitivity In Age-Related Macular Degeneration At Varying Luminance Levels, Joao Alhada Lourenco
School of Health Professions Theses
Age-related macular degeneration is a common ocular condition in the older adult population, being the leading cause of visual impairments in industrialised countries. The prevalence of age-related macular degeneration is expected to increase along with increased life-expectancy. The early stages of age-related macular degeneration often present no noticeable symptoms; however, visual function may be impaired, particularly under low light conditions. An initial impairment tends to occur in the parafoveal region where rod photoreceptors are denser, as these photoreceptors were shown to be more prone to dysfunction than cone photoreceptors in early stages of age-related macular degeneration. Therefore, testing for this …
Mapping The Uk Commercial Fishing Network: A Knowledge-Based Framework For Sustainable Technology Adoption And Environmental Decision-Making, Matthew Prowse
Mapping The Uk Commercial Fishing Network: A Knowledge-Based Framework For Sustainable Technology Adoption And Environmental Decision-Making, Matthew Prowse
School of Engineering, Computing and Mathematics Theses
The UK commercial fishing industry operates within a complex web of stakeholders, technologies, and environmental pressures that challenge traditional approaches to sustainability and resource management. This research develops a comprehensive framework for understanding how technological advancement in UK fisheries creates unintended consequences that threaten long-term sustainability. Through a mixed-methods approach combining PESTLE analysis, grounded theory methodology, stakeholder mapping, case study investigation, this study introduces the "By-Product and Excess" theoretical framework to explain how fishing technologies generate two critical outcomes: by-products (undesirable environmental impacts such as CO₂ emissions, microplastics, and ecosystem damage) and excess (enhanced capacity to harvest beyond sustainable limits).The …
Investigating The Biocompatibility Of Nanosilver Hydroxyapatite Coatings With Human Gingival Fibroblasts To Enhance Abutment Integrity For Periodontal Health, Sian Morgan
School of Engineering, Computing and Mathematics Theses
Dental implants are susceptible to bacterial colonisation, which can initiate peri-implant inflammation and ultimately lead to peri-implantitis and implant failure. Antimicrobial surface modifications represent a promising strategy to mitigate bacterial infection however, such approaches must preserve biocompatibility with peri-implant soft tissue cells to ensure effective mucosal sealing and long-term implant success. In particular, human gingival fibroblasts (HGFs) play a critical role in soft tissue integration at the implant-abutment interface, yet their interactions with antimicrobial silver-based coatings remain insufficiently understood. This thesis investigates the biocompatibility of nano silver-hydroxyapatite (Ag+nHA) coatings deposited on titanium substrates, with the aim of developing an antimicrobial …
A General Tool To Assist With On Orbit Manufacturing, Richard Arundal
A General Tool To Assist With On Orbit Manufacturing, Richard Arundal
School of Engineering, Computing and Mathematics Theses
On-Orbit Manufacturing (OOM) presents a transformative paradigm in space mission design, enabling the in-situ production of components, tools, and large-scale structures beyond terrestrial constraints. This dissertation investigates the feasibility of OOM missions by developing a modular, iterative algorithm to support early-stage mission design and scenario analysis. The central hypothesis is that such an algorithm can be parameterised to evaluate a wide spectrum of manufacturing cases in space, ranging from small utility items to large structural systems.The research pursues four core objectives: assessing the terrestrial manufacturing lifecycle and its applicability in the space environment; identifying candidate manufacturing techniques suitable for orbital …
How Does Pre-Registration Child Specific Education Prepare Newly Qualified Nurses’ To Care For Children, Young People, And Their Families? An Empty Narrative Review, Matt Carey, Danielle Edge, Julie Blamires, Mandie Foster, Sarah Neill
How Does Pre-Registration Child Specific Education Prepare Newly Qualified Nurses’ To Care For Children, Young People, And Their Families? An Empty Narrative Review, Matt Carey, Danielle Edge, Julie Blamires, Mandie Foster, Sarah Neill
School of Nursing and Midwifery
This narrative review investigates the influence of child-specific content within pre-registration nursing programs on newly qualified nurses’ perceptions of preparedness to care for children, young people, and their families. Despite international recognition of the specialised competencies required for pediatric nursing, the proportion and quality of child-focused education across Higher Education Institutions is not clear. The Population, Exposure, Outcome framework provided a comprehensive search strategy applied across eight databases to identify relevant studies that met the inclusion and exclusion criteria. Of 663 records identified, 451 were screened and 25 full texts wereassessed for eligibility by two reviewers. No studies met the …
Exploring The Reading Motivation And Reading Experiences Of Secondary School Students With Dyslexia In England, Ahmet Kaan Alper
Exploring The Reading Motivation And Reading Experiences Of Secondary School Students With Dyslexia In England, Ahmet Kaan Alper
School of Law, Humanities and Social Sciences Theses
This research examines how a small group of secondary school students with dyslexia in England make sense of their reading experiences and motivation to read across school, home and everyday settings. It responds to concerns that literacy policy and practice foreground accuracy, speed and comparison, leaving limited space for reading for pleasure on students’ own terms. Drawing on Michel Foucault’s concepts, the study treats dyslexia and literacy as historically and institutionally produced categories and explores how discourses, norms and accountability regimes shape what counts as legitimate reading and a motivated reader. The research is grounded in a relativist ontology and …
Safe Family Therapy Activities And The Emotional Well-Being Of Parents Of Autistic Children, Gamze Camci
Safe Family Therapy Activities And The Emotional Well-Being Of Parents Of Autistic Children, Gamze Camci
School of Law, Humanities and Social Sciences Theses
This thesis addresses a critical gap in the existing literature on the emotional well-being of parents of autistic children by applying SAFE family therapy activities grounded in the Narrative Attachment Therapy approach through a three-cycle action research design. Stage 1 involved 3 parents as primary participants, with their children present during selected sessions. Stage 2 included 2 families; the primary focus was on 3 parents across these families. Stage 3 engaged 5 therapists. Data were collected through interviews, diaries, questionnaires and therapy recordings. Data from interviews and journals were analysed thematically, whereas questionnaires were analysed idiographically. The first and second …