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Non - Legitimate Illness, Embodied Experience And The Moral Career: The Case Of Me/Cfs, Tracey Collett Jan 2002

Non - Legitimate Illness, Embodied Experience And The Moral Career: The Case Of Me/Cfs, Tracey Collett

School of Law, Humanities and Social Sciences Theses

The condition known as myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is an illness of unknown aetiology which affects over 150 000 persons in the UK. Whilst the cause of the condition is the subject of intense medical debate, the official view is that it is a form of atypical depression or somatisation disorder. This view is at odds with the views of many sufferers who claim that ME/CFS is a pathological disease that renders them severely incapacitated. Sufferers' maintain that, because their condition is regarded as a minor, psychological illness, its' severity is not recognised. Thus, rather than being …

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Uk Survey Of Discharge Prescriptions, Transcribing And Development Of The Hospital Pharmacist-Prescribing Role, Gj Sewell, Rj Hobson Jan 2002

Uk Survey Of Discharge Prescriptions, Transcribing And Development Of The Hospital Pharmacist-Prescribing Role, Gj Sewell, Rj Hobson

School of Health Professions

No abstract provided.

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Factors Influencing Provision Of Pharmacist Discharge Prescription Transcription Services And Authorisation Requirements Of Pharmacist-Written Prescriptions, Gj Sewell, Rj Hobson Jan 2002

Factors Influencing Provision Of Pharmacist Discharge Prescription Transcription Services And Authorisation Requirements Of Pharmacist-Written Prescriptions, Gj Sewell, Rj Hobson

School of Health Professions

No abstract provided.

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The Adaptive Advantage Of Symbolic Theft Over Sensorimotor Toil: Grounding Language In Perceptual Categories, A Cangelosi, S Harnad Jan 2002

The Adaptive Advantage Of Symbolic Theft Over Sensorimotor Toil: Grounding Language In Perceptual Categories, A Cangelosi, S Harnad

School of Engineering, Computing and Mathematics

Using neural nets to simulate learning and the genetic algorithm to simulate evolution in a toy world of mushrooms and mushroom-foragers, we place two ways of acquiring categories into direct competition with one another: In (1) "sensorimotor toil,” new categories are acquired through real-time, feedbackcorrected, trial and error experience in sorting them. In (2) "symbolic theft,” new categories are acquired by hearsay from propositions – boolean combinations of symbols describing them. In competition, symbolic theft always beats sensorimotor toil. We hypothesize that this is the basis of the adaptive advantage of language. Entry-level categories must still be learned by toil, …

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Pharmacokinetics Of Doxorubicin And Cisplatin After Administration By Avitine/Omnipaque Gel Applied Directly To The Liver, Gj Sewell, M Priston, T Manoj, R Duncombe Jan 2002

Pharmacokinetics Of Doxorubicin And Cisplatin After Administration By Avitine/Omnipaque Gel Applied Directly To The Liver, Gj Sewell, M Priston, T Manoj, R Duncombe

School of Health Professions

No abstract provided.

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Identification Of An Mcm4 Homologue Expressed Specifically In The Sexual Stage Of Plasmodium Falciparum, J-L Li, Ls Cox Sep 2001

Identification Of An Mcm4 Homologue Expressed Specifically In The Sexual Stage Of Plasmodium Falciparum, J-L Li, Ls Cox

School of Biomedical Sciences

Mini-chromosome maintenance (MCM) proteins play an essential role in DNA replication initiation. We have isolated a novel gene encoding an MCM-like protein from the human malaria parasite Plasmodium falciparum using the vectorette technique. The gene has no introns and comprises an open reading frame encoding 1005 amino acid residues with a predicted Mr of 115 kDa. The encoded protein, termed PfMCM4, contains all conserved sequences in the MCM family and displays the highest homology to the Cdc54 (MCM4) of Saccharomyces cerevisiae. However, PfMCM4 possesses five unique amino acid inserts with sizes ranging from seven to 75 residues. Southern blotting of …

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Primary Structure And Sexual Stage-Specific Expression Of A Lammer Protein Kinase Of Plasmodium Falciparum, J-L Li, Gat Targett, Da Baker Apr 2001

Primary Structure And Sexual Stage-Specific Expression Of A Lammer Protein Kinase Of Plasmodium Falciparum, J-L Li, Gat Targett, Da Baker

School of Biomedical Sciences

We have isolated a LAMMER-like gene from Plasmodium falciparum by vectorette technique. The gene consists of 3316 bp encoding a protein 881 amino acids with a predicted molecular mass of approximately 106.7 kDa. The encoded protein, termed PfLAMMER, is composed of two distinct domains. The N-terminal domain is not related to any previously described protein kinases and has several interesting features including multiple consensus phosphorylation sites for a range of protein kinases, a number of RS/SR dipeptides, a large proportion of charged amino acids, two putative nuclear localisation signals and 14 copies of a tetramer DKYD repeats. The C-terminal domain …

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Management In The Financial Services : Emotional Labour And Gender, Sarah Watson Jan 2001

Management In The Financial Services : Emotional Labour And Gender, Sarah Watson

School of Law, Humanities and Social Sciences Theses

This thesis examines the development of management in financial services and its implications on managers' activities and socialisation. The thesis uses gender and emotional labour as the main themes for the discussion of management in the financial services. The thesis reports on two ethnographic case studies within two UK retail banks. Analyses are based on data derived from interviews, observations and documents. Both the literature and data suggest that management in the service sector centres around the management of organisational cultures. Managers must disseminate the organisational values in order to extract excellent customer service from the front-line staff. Managers themselves …

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Mass Transport By Non-Linear Internal Waves On The Malin Shelf, Me Inall, Gi Shapiro, Tj Sherwin Jan 2001

Mass Transport By Non-Linear Internal Waves On The Malin Shelf, Me Inall, Gi Shapiro, Tj Sherwin

School of Biological and Marine Sciences

No abstract provided.

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Multivariate Calibration For Icp-Aes, Michael Lee Griffiths Jan 2001

Multivariate Calibration For Icp-Aes, Michael Lee Griffiths

School of Geography, Earth and Environmental Sciences Theses

The analysis of metals is now a major application area for ICP-AES, however, the technique suffers from both spectral and non-spectral interferences. This thesis details the application of univariate and multivariate calibration methods for the prediction of Pt, Pd, and Rh in acid-digested and of Au, Ag and Pd in fusion-digested autocatalyst samples. Of all the univariate calibration methods investigated matrix matching proved the most accurate method with relative root mean square errors (RRMSEs) for Pt, Pd and Rh of 2.4, 3.7, and 2.4 % for a series of synihelic lest solutions, and 12.0, 2.4, and 8.0 % for autocatalyst …

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Determination Of Co And Mn In Marine Waters Using Flow Injection With Chemiluminescence Detection, Vincenzo Cannizzaro Jan 2001

Determination Of Co And Mn In Marine Waters Using Flow Injection With Chemiluminescence Detection, Vincenzo Cannizzaro

School of Geography, Earth and Environmental Sciences Theses

This thesis describes the design, optimisation and shipboard deployment of a flow injection - chemiluminescence (FI-CL) technique for the determination of cobalt (Co) and manganese (Mn) in seawater. Chapter One presents an overview of the marine environment and the biogeochemistry of Co and Mn. Current analytical methods for the determination of Co and Mn in natural waters are also reviewed. Chapter Two reports reagent clean-up techniques and the synthesis of an 8- hydroxyquinoline resin used for in-line matrix elimination and preconcentration. The resin is also characterised in terms of its chelating ability for the transition metals and the earth alkaline …

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Catchment Scale Monitoring And Modelling Of Phosphorus Using Flow Injection Analysis And An Export Coefficient Model, Grady Scott Hanrahan Jan 2001

Catchment Scale Monitoring And Modelling Of Phosphorus Using Flow Injection Analysis And An Export Coefficient Model, Grady Scott Hanrahan

School of Geography, Earth and Environmental Sciences Theses

Acquiring high quality in situ analytical data with good temporal resolution is required for developing models of phosphorus transport and biogeochemical behaviour. Chapter One describes the behaviour of phosphorus in the aquatic environment, its sources, its role in the eutrophication process and legislation to control its release into aquatic systems. It also summarises analytical techniques for the determination of phosphorus in natural waters. An examination of the hypothesis that the export coefficient modelling approach can be used to predict phosphorus loading in the River Frome catchment, Dorset on an armual and seasonal (monthly) basis is presented in Chapter Two. The …

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The Development Of A Holistic Expert System For Integrated Coastal Zone Management, Antoni Bruce Moore Jan 2001

The Development Of A Holistic Expert System For Integrated Coastal Zone Management, Antoni Bruce Moore

School of Geography, Earth and Environmental Sciences Theses

Coastal data and information comprise a massive and complex resource, which is vital to the practice of Integrated Coastal Zone Management (ICZM), an increasingly important application. ICZM is just as complex, but uses the holistic paradigm to deal with the sophistication. The application domain and its resource require a tool of matching characteristics, which is facilitated by the current wide availability of high performance computing. An object-oriented expert system, COAMES, has been constructed to prove this concept. The application of expert systems to ICZM in particular has been flagged as a viable challenge and yet very few have taken it …

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Interagency Coordination And Collaboration In The Management Of Child Sexual Abuse: In Australian And England, Anne Margaret Lawrence Jan 2001

Interagency Coordination And Collaboration In The Management Of Child Sexual Abuse: In Australian And England, Anne Margaret Lawrence

Other Faculty of Health Theses

This thesis focuses on interagency coordination and collaboration in the management of child sexual abuse in Australia and in England. The impetus for the research arose from the experience of the author as manager and practitioner in the area of child sexual abuse, while working in these two countries. Problems regarding the management of interagency cooperation had become apparent in child protection practice and were also recognized in the literature. Personal experience, as well as a review of the literature, revealed that there was a need for the identification and validation of the key mechanisms and processes underlying effective interagency …

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Cytokine Expression In Patients With B-Cell Chronic Lymphocytic Leukaemia, Anna Kaminski Jan 2001

Cytokine Expression In Patients With B-Cell Chronic Lymphocytic Leukaemia, Anna Kaminski

Other Faculty of Health Theses

B-cell chronic lymphocytic leukaemia (B-CLL) results from a clonal accumulation of CD5+ve B-lymphocytes. This expansion of B-lymphocytes is due to increased proliferation and extended survival secondary to decreased apoptosis. Both proliferation and apoptosis are regulated by a group of soluble proteins, termed cytokines, which are secreted by cells and play a key role in the regulation of immunological responses. In view of this, the role of cytokines in the pathogenesis of B-CLL was studied. Interleukin 4 (IL-4) is an anti-apoptotic cytokine which up-regulates bcl-2 in malignant B-lymphocytes. Peripheral blood samples, from untreated B-CLL patients were investigated, together with a group …

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Treatment Of Musculoskeletal Pain With The Sting Of The Stinging Nettle: Urtica Dioica, Colin F Randall Jan 2001

Treatment Of Musculoskeletal Pain With The Sting Of The Stinging Nettle: Urtica Dioica, Colin F Randall

Peninsula Medical School Theses

Introduction The author's interest in the therapeutic potential of the sting of nettles began with the presentation of two patients in his general practice surgery who were self-prescribing nettle sting for their arthritis pain. The publication of these two case reports produced responses from four other doctors about similar cases. Historical and contemporary research An extensive literature and database review produced few references from the medical literature but numerous anecdotal references from herbal and folklore sources of worldwide internal and external use of nettle since Roman times. The author has been asked to contribute two chapters on the historical and …

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Bullying In A Primary School : A Case Study, Christopher Graham Lee Jan 2001

Bullying In A Primary School : A Case Study, Christopher Graham Lee

Plymouth Institute of Education Theses

Bullying has become a significant issue for schools and one that has attracted the media spotlight. It has also received considerable attention from the research community since the late 1980s following the tradition established through the work of many Scandinavian researchers. Much of the research has been longitudinal and sought to illuminate the experience of children who bullied or were being bullied. There has been considerably less research into teachers' and parents' understanding and experience of bullying between school children. This thesis seeks to rectify that situation by examining the views of Year 5 and 6 pupils, teachers and a …

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Measurement And Modelling Of Uranium And Thorium In Natural Waters, Ernily Rachel Unsworth Jan 2001

Measurement And Modelling Of Uranium And Thorium In Natural Waters, Ernily Rachel Unsworth

School of Geography, Earth and Environmental Sciences Theses

Uranium and thorium are the only elements in the actinide series which naturally occur in the environment in sufficient amounts for practical extraction. They are both radiotoxic and chemotoxic to humans due to the effects of the ionising radiation produced by their radioactive decay, the decay of their daughter products, and due to the chemical toxicity resulting from absorption into the body. Thus it is important to be able to quantitatively determine the levels of uranium and thorium in the environment. Measurement of low levels of uramum and thorium in the presence of high levels of inorganic and organic matrix …

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The Synthesis Of Estuarine Bathymetry From Sparse Sounding Data, Janet Eirlys Burroughes Jan 2001

The Synthesis Of Estuarine Bathymetry From Sparse Sounding Data, Janet Eirlys Burroughes

Other Faculty of Science and Engineering Theses

The two aims of the project involved: 1. Devising a system for prediction o f areas of bathymetric change within the Fal estuary 2. Formulating and evaluating a method for interpolating single beam acoustic bathymetry to avoid artefacts o f interpolation. In order to address these aims, sources of bathymetric data for the Fal estuary were identified as Truro Harbour Office, Cornwall County Council and the Environment Agency. The data collected from these sources included red wavelength Lidar, aerial photography and single beam acoustic bathymetry from a number of different years. These data were input into a Geographic Information System …

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The Relationship Between Livestock Distribution Channels And Animal Welfare, Karen Christina Murray Jan 2001

The Relationship Between Livestock Distribution Channels And Animal Welfare, Karen Christina Murray

Other Faculty of Science and Engineering Theses

Major changes are taking place in all sectors of the livestock and meat producing industries from farm to consumer which impinge on the processes and patterns of livestock distribution from farm to slaughter. These changes are identified and described. A survey of the complete journeys from farm to abattoir of 18,393 slaughterweight lambs sold direct from farm to abattoir, via livestock auction markets and via electronic auctions was conducted. Lambs sold direct from farm to abattoir experienced shorter journeys (in terms of both median duration and distance) than lambs sold through either of the other two channels. Lambs sold through …

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Implementing Marine Pollution Policy : Proposals For Change, Jonathan Peter Richards Jan 2001

Implementing Marine Pollution Policy : Proposals For Change, Jonathan Peter Richards

Other Faculty of Science and Engineering Theses

This study aims to determine the factors that affect the implementation of marine pollution policy, especially with regard to regulation of the hazardous substances which contaminate the marine environment- The purpose is to identify weaknesses in the current regulatory regime and to propose improvements. The study also aims to develop a new strategic framework for the implementation of the recent international policy commitments, which call for the complete cessation of discharges of hazardous substances into the marine environment by the year 2020. Furthermore, the study seeks to provide evidence to support or challenge current theories relating to regulation and policy …

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Developments And Benefits Of Liquid Feeding Through Fermentation For The Post-Weaned Pig, Colm Anthony Moran Jan 2001

Developments And Benefits Of Liquid Feeding Through Fermentation For The Post-Weaned Pig, Colm Anthony Moran

Other Faculty of Science and Engineering Theses

A programme of study was undertaken to assess the safety and palatability of fermented liquid feed. A series of laboratory experiments was conducted to select an inoculant capable of fermenting liquid feed at 20°C. Whilst combinations of cultures dropped the pH the most rapidly, the Lb. plantarum (PC) strain decreased the pH the lowest. A series of trials were conducted using a rifampicin mutant of Lb. plantarum (PC) to examine the fate of the starter culture. In an experiment using liquid milled wheat the addition of the starter culture resulted in an improvement in the inhibition of coliforms over the …

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The Importance Of Being : The Autobiographical Subject In The Drama And Memoirs Of Ronald Duncan, Anna Claire Trussler Jan 2001

The Importance Of Being : The Autobiographical Subject In The Drama And Memoirs Of Ronald Duncan, Anna Claire Trussler

Other Faculty of Arts, Humanities and Business Theses

This study developed after considerable time spent collating and cataloguing data contained in Ronald Duncan's archive. Familiarisation with the material led to my identifying a need to explore the elusive nature of the personality that biographical material should hope to uncover. Duncan was prone to mainly confessional writing, a kind of writing that demands a causal inference between life and work. Furthermore, the archive supplies multiple data sources that serve to aid chronology, trace reliability, provide external corroboration and investigate truth-value. My study follows a loosely chronological structure after discerning shifts in his thematic concerns. The years up until the …

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Poetic Anatomy Of The Numinous Creative Passages Into The Self As Beloved, Partou Zia Jan 2001

Poetic Anatomy Of The Numinous Creative Passages Into The Self As Beloved, Partou Zia

Other Faculty of Arts, Humanities and Business Theses

This research is shaped by the actual experience of practice: as painter and writer. My preoccupation is with the nodal moment when conscious awareness is suspended, and both the corporal and psychic involvement in realising the work almost transport one to another zone of effectiveness. This zone, which I name as the poetic zone, is where the numinous enters the ordinary. The investigation for a space/place/moment that lies beyond the logic of acceptable discourse can help initiate and give shape to a new vocabulary - visual or literary. By orchestrating a methodology, which functions on several layers, I have endeavoured …

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From Rio To Romola: Morality And Didacticism In The English Appreciation Of Early Italian Art 1836-1863, Matthew T.W. Plampin Jan 2001

From Rio To Romola: Morality And Didacticism In The English Appreciation Of Early Italian Art 1836-1863, Matthew T.W. Plampin

Other Faculty of Arts, Humanities and Business Theses

This thesis takes as its starting point the marked rise in interest in the earlier schools of Italian painting in the English art world during the 1840s. Over the course of this decade the study and collection of so-called 'primitive' painting was transformed from a marginal pursuit to an aspect of mainstream taste. The thesis defines the critical discourse formulated in order to rationalise the taste for art works which failed to conform to the principles which had governed the appreciation of old master painting in previous decades. It also studies the ramifications of this discourse with regards to broader …

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An Investigation Into The Factors Determining Ruminant Livestock Distribution In The Far South West, Dafydd Huw Davies Jan 2001

An Investigation Into The Factors Determining Ruminant Livestock Distribution In The Far South West, Dafydd Huw Davies

Other Faculty of Arts, Humanities and Business Theses

Major changes are taking place in all sectors of the livestock and meat producing industries from farm to consumer which impinge on the processes and pattems of livestock distribution from farm to slaughter. These changes are identified and described. A farm business survey of lowland beef and sheep finishers was undertaken, prior to the 2001 Foot and Mouth outbreak, to gain a better understanding of farm business behaviour in order to model the farm business strategies in relation to aggregate livestock channel utilisation. Statistically robust and predictive models using a number of derived latent strategic variables, distilling marketing and business …

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Methodological Embodiments:: Psychical Corporeal Performances Of Subjective Specific Auto[Erotic)-Representations, Ryya Aviva Sanders Jan 2001

Methodological Embodiments:: Psychical Corporeal Performances Of Subjective Specific Auto[Erotic)-Representations, Ryya Aviva Sanders

Other Faculty of Arts, Humanities and Business Theses

A great deal of critical attention has been paid over the last twenty years at least to the relation of 'self and 'Other'. But what happens when the external 'other' is displaced to the periphery of the concerns of textual production? In order to explore this question Methodological Embodiments employs an interdisciplinary praxis that is not limited to the classic model of written theory. At the same time, it does not negate this form that has historical and ideological precedence within an academic context. The aim of this thesis is to juxtapose written theory with artistic practices in order to …

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Studies In Agricultural Technology In Nineteenth- And Twentieth-Century England, Paul William Brassley Jan 2001

Studies In Agricultural Technology In Nineteenth- And Twentieth-Century England, Paul William Brassley

Other Faculty of Science and Engineering Theses

Four published papers and several parts of a book are presented herein, together with a previously unpublished short paper explaining the intellectual background against which they were written and summarising their findings on the development of agricultural teQmology in England in the nineteenth and twentieth centuries. This outlines the contribution of economic and sociological the^pries to the study of technical change, but makes the point that historical studies, although clearly influenced by these theories, tend to use a multifactorial approach which avoids privileging any single explanation. Nevertheless, several themes arising in all of this material are identified, especially the gap …

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The Decision To Undertake Vocational Higher Education In Shipping And Logistics In The Uk, John Dinwoodie Jan 2001

The Decision To Undertake Vocational Higher Education In Shipping And Logistics In The Uk, John Dinwoodie

Other Faculty of Science and Engineering Theses

This work investigates the decision to study shipping and logistics at advanced levels in the UK. Documented evidence reports and analyses the perceptions of students on vocational courses in shipping, transport and logistics and investigates why they chose their particular fields of study. A range of instruments are presented to analyse how students perceived that they had arrived at their study decisions, including national surveys of undergraduates in maritime business, postgraduates in shipping and logistics and professionals contemplating updating short courses. Qualitative, quantitative and mapping methods are presented along with perceptions of relevant professional outcome roles and other factors. Exploratory …

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Phonographies: Practical And Theoretical Explorations Into Composing With Disembodied Sound, John Levack Drever Jan 2001

Phonographies: Practical And Theoretical Explorations Into Composing With Disembodied Sound, John Levack Drever

Other Faculty of Arts, Humanities and Business Theses

This is PhD submission is both practical and theoretical. The practical element consists of nine electroacoustic compositions. The dissertation acts as a discursive accompaniment to the compositions, addressing many of the contextual and philosophical issues that have arisen during the compositional process and the perfannance of the works. It charts out discourse surrounding the different genres of electroacoustic music that the works relate to as well as examining models of work in the respective genres (i. e. sonic art, text.. sound, acousmatic composition, inusique concrite and soundscape composition), and places them into a broader cultural and historical context. Chapter 2 …

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