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The Development And Optimization Of Microbial Molecular Biomarkers For The In Situ Assessment Of Trace Metal Toxicity, Nicolas James Bouskill Jan 2006

The Development And Optimization Of Microbial Molecular Biomarkers For The In Situ Assessment Of Trace Metal Toxicity, Nicolas James Bouskill

School of Biological and Marine Sciences Theses

Microorganisms are fundamental components of many geochemical transformations occurring in the aquatic environment. Microbial redox and methylation of metals within the environment can alter metal speciation, mobility and ultimately, toxicity to eukaryotes. It is therefore practical that any environmental monitoring framework advocating the application of `early-warning biomarker system' should incorporate a holistic view of the environment beginning with microbial activity. This thesis describes the development of protocols for assessing the in situ condition of microbial ecosystems within a gradient of metal contaminated sites radiating downstream of the Anaconda Smelter, a USEPA-designated superfund site and within two control sites. Experiments focus …

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The Potential Use Of (1→3, 1→4)-Β-D-Glucan From Barley As A Functional Food Ingredient For Cereal Foods, Louise Jane Cleary Jan 2006

The Potential Use Of (1→3, 1→4)-Β-D-Glucan From Barley As A Functional Food Ingredient For Cereal Foods, Louise Jane Cleary

School of Biological and Marine Sciences Theses

The health related importance of dietary fibre as part of a balanced diet is well known. More recently, soluble fibres, such as (1→3, 1→4)-β-D-glucan (β-glucan), have been shown to influence glycaemic, insulin and cholesterol responses to foods. Barley is a rich source of β-glucan; however, consumption of products containing barley grain or flour is often limited by their negative organoleptic quality. A potential solution lies in the use of barley as an extraction source for β-glucan fractions. One problem with regards to this is the lack of clarity on the use of barley β-glucan fractions in food systems, particularly their …

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Investigating The Processing Style Account Of The Effects Of Naval Processing On Face Recognition Performance, Nicola Jane Weston Jan 2006

Investigating The Processing Style Account Of The Effects Of Naval Processing On Face Recognition Performance, Nicola Jane Weston

School of Psychology Theses

Engaging in Navon processing prior to face recognition influences recognition performance (Macrae & Lewis, 2002; Perfect, 2003; Weston & Perfect, 2005). Past research has shown that global Navon processing can improve face recognition accuracy whereas local Navon processing impairs it. One explanation, and the dominant one in the literature, is that the Navon letter task elicits holistic and featural processing styles which map onto the holistic and featural processing used in face recognition. However, this theory has not been extensively tested in the literature. This thesis investigates whether processing style can explain the effects caused by the Navon letter task, …

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Structure Of Late Variscan Millevaches Leucogranite Massif In The French Massif Central: Ams And Gravity Modelling Results, A Gébelin, G Martelet, Y Chen, M Brunel, M Faure Jan 2006

Structure Of Late Variscan Millevaches Leucogranite Massif In The French Massif Central: Ams And Gravity Modelling Results, A Gébelin, G Martelet, Y Chen, M Brunel, M Faure

School of Geography, Earth and Environmental Sciences

In the Limousin area, Variscan leucogranitic plutons are spatially associated with normal faults and major strike-slip shear zones that are a continuation of the South Armorican shear zone. Our study focuses on the large N-S-trending Millevaches granitic massif (Massif Central, France), and intends to highlight, through gravity modelling, structural and anisotropy of magnetic susceptibility (AMS), the massif structure at depth and to discuss the mode of emplacement of granites within a strike-slip tectonic context. The mica subfabric suggests that the magnetic foliations display a general NW-SE sub-horizontal pattern on both sides of the N-S Pradines dextral wrench fault zone that …

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Studies On The Decontamination Of Surfaces Exposed To Cytotoxic Drugs In Chemotherapy Workstations, Gj Sewell, S Roberts, N Khammo, G Mcdonnell Jan 2006

Studies On The Decontamination Of Surfaces Exposed To Cytotoxic Drugs In Chemotherapy Workstations, Gj Sewell, S Roberts, N Khammo, G Mcdonnell

School of Health Professions

No abstract provided.

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The Future Of Student Grouping Systems In Science 14-16., Stephen Rowcliffe Jan 2006

The Future Of Student Grouping Systems In Science 14-16., Stephen Rowcliffe

School of Law, Humanities and Social Sciences

Ability grouping is a contentious issue in high school science education, and one that divides teachers,parents, and policymakers alike. However, it may be that current grouping systems are founded on ideasthat are failing to provide for the best interests of students at any ability level. This article aims to reviewcurrent practice and its effects on student and teacher outcomes, and suggest a new direction for studentgrouping polices based on the ideal of “science for all” through curriculum reform and choice-basedmodular course systems. The article is based largely on the British education system.

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Managing Fisheries Resources In Kaptai Reservoir, Bangladesh, Kku Ahmed, S Rahman, Su Ahammed Jan 2006

Managing Fisheries Resources In Kaptai Reservoir, Bangladesh, Kku Ahmed, S Rahman, Su Ahammed

School of Geography, Earth and Environmental Sciences

This paper examines the various challenges facing the development of fisheries resources in Kaptai reservoir, Bangladesh. The reservoir has undergone major changes in its catch composition since impoundment. Production records show a declining trend in the productivity of high-value fish. A host of managerial, socioeconomic and environmental factors are responsible for the underutilization of the reservoir's potential to provide high-value freshwater fish. These include deterioration of the natural breeding ground, environmental damage, poor implementation of regulations, inefficient fish farming technology and poor management practices. These constraints are discussed and possibilities for future improvements are suggested.

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Preliminary Findings From A Study Of The Upper Reaches Of The Tamar Estuary, Uk, Throughout A Complete Tidal Cycle: Part I. Linking Sediment And Hydrodynamic Cycles, Sj Bass, Aj Manning, Kr Dyer Jan 2006

Preliminary Findings From A Study Of The Upper Reaches Of The Tamar Estuary, Uk, Throughout A Complete Tidal Cycle: Part I. Linking Sediment And Hydrodynamic Cycles, Sj Bass, Aj Manning, Kr Dyer

School of Biological and Marine Sciences

No abstract provided.

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Amplification And Suppression Of Internal Waves By Tides Over Variable Bottom Topography, Vasiliy Vlasenko, Nataliya Stashchuk Jan 2006

Amplification And Suppression Of Internal Waves By Tides Over Variable Bottom Topography, Vasiliy Vlasenko, Nataliya Stashchuk

School of Biological and Marine Sciences

The energy exchange between internal waves and barotropic currents over inclined bottom topography is studied theoretically and in the framework of the numerical model. The energy balance equation derived for a continuously stratified fluid predicts that energy can either be transferred toward or away from the internal wave depending on the direction of propagation of both the wave and current. Four scenarios of wave-flow interaction over the inclined bottom were identified. An internal wave extracts energy from the background tidal flow during its propagation upslope-upstream or downslope-downstream and its amplitude grows. The wave loses energy propagating downslope-upstream or upslope-downstream and …

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Durum Wheat Quality I: Some Physical And Chemical Characteristics Of Syrian Durum Wheat Genotypes, Gh El-Khayat, A Samaan, Fa Manthey, Mp Fuller, Cs Brennan Jan 2006

Durum Wheat Quality I: Some Physical And Chemical Characteristics Of Syrian Durum Wheat Genotypes, Gh El-Khayat, A Samaan, Fa Manthey, Mp Fuller, Cs Brennan

School of Biological and Marine Sciences

Some physical and chemical characteristics of nine Syrian durum wheat genotypes were determined in order to investigate the relationships among individual kernel components and kernel quality. All genotypes were grown on fully irrigated plots in Syria. Test weight, 1000-kernel weight, kernel size distribution, hardness and semolina extraction rates were determined along with the chemical characteristics of the kernel (ash, moisture, protein, wet gluten, starch content and falling number). All tested genotypes had high test weight (83.1–85.9 kg hl−1) and 1000-kernel weight (42.5–55.5 g) indicating high milling yield potential. Additionally, all the wheat genotypes demonstrated high falling numbers (433–597 s). Correlation …

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Endogenous Human Cytomegalovirus Gb Is Presented Efficiently By Mhc Class Ii Molecules To Cd4+ Ctl, Nagendra R. Hegde, Claire Dunn, David M. Lewinsohn, Michael A. Jarvis, Jay A. Nelson, David C. Johnson Oct 2005

Endogenous Human Cytomegalovirus Gb Is Presented Efficiently By Mhc Class Ii Molecules To Cd4+ Ctl, Nagendra R. Hegde, Claire Dunn, David M. Lewinsohn, Michael A. Jarvis, Jay A. Nelson, David C. Johnson

School of Biomedical Sciences

Human cytomegalovirus (HCMV) infects endothelial, epithelial, and glial cells in vivo. These cells can express MHC class II proteins, but are unlikely to play important roles in priming host immunity. Instead, it seems that class II presentation of endogenous HCMV antigens in these cells allows recognition of virus infection. We characterized class II presentation of HCMV glycoprotein B (gB), a membrane protein that accumulates extensively in endosomes during virus assembly. Human CD4+ T cells specific for gB were both highly abundant in blood and cytolytic in vivo. gB-specific CD4+ T cell clones recognized gB that was expressed in …

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Simultaneous Determination Of Dissolved Organic Carbon And Total Dissolved Nitrogen On A Coupled High-Temperature Combustion Total Organic Carbon-Nitrogen Chemiluminescence Detection (Htc Toc-Ncd) System, X Pan, R Sanders, Ad Tappin, Pj Worsfold, Ep Achterberg Aug 2005

Simultaneous Determination Of Dissolved Organic Carbon And Total Dissolved Nitrogen On A Coupled High-Temperature Combustion Total Organic Carbon-Nitrogen Chemiluminescence Detection (Htc Toc-Ncd) System, X Pan, R Sanders, Ad Tappin, Pj Worsfold, Ep Achterberg

School of Geography, Earth and Environmental Sciences

The marine biogeochemistries of carbon and nitrogen have come under increased scrutiny because of their close involvement in climate change and coastal eutrophication. Recent studies have shown that the high-temperature combustion (HTC) technique is suitable for routine analyses of dissolved organic matter due to its good oxidation efficiency, high sensitivity, and precision. In our laboratory, a coupled HTC TOC-NCD system with a sample changer was used for the automated and simultaneous determination of dissolved organic carbon (DOC) and total dissolved nitrogen (TDN) in seawater samples. TOC control software was used for TOC instrument control, DOC data acquisition, and data analysis. …

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Severe Tissue Damage And Neurological Deficit Following Extravasation Of Sodium Hypochlorite Solution During Routine Endodontic Treatment., R. Witton, P. A. Brennan Jun 2005

Severe Tissue Damage And Neurological Deficit Following Extravasation Of Sodium Hypochlorite Solution During Routine Endodontic Treatment., R. Witton, P. A. Brennan

Peninsula Dental School

Endodontic therapy is a routinely practised clinical procedure with few reported complications. Sodium hypochlorite is often used as an irrigant during this procedure, but severe complications may occur if this solution extravasates beyond the root apex. We present a case demonstrating some of the severe sequelae that can occur following the misuse of sodium hypochlorite during endodontic treatment of an upper lateral incisor, which also resulted in the previously unreported complication of isolated facial nerve weakness.

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Doctoral Thesis Examination Defence Seminar, Tj Lynch Jun 2005

Doctoral Thesis Examination Defence Seminar, Tj Lynch

Plymouth Institute of Education

Lynch, T. (2005, June 7). An evaluation of school responses to the introduction of the Queensland 1999 health and physical education (HPE) syllabus and policy documents in three Brisbane Catholic Education (BCE) primary schools. Doctoral Thesis Examination Defence Seminar, Faculty of Education, Australian Catholic University (Qld).

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Report Of The Working Group On Deep-Water Ecology (Wgdec), 8-11 March 2005, Jm Hall-Spencer Mar 2005

Report Of The Working Group On Deep-Water Ecology (Wgdec), 8-11 March 2005, Jm Hall-Spencer

School of Biological and Marine Sciences

No abstract provided.

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Sharing Research In Health And Physical Education, Tj Lynch Mar 2005

Sharing Research In Health And Physical Education, Tj Lynch

Plymouth Institute of Education

Lynch, T. (2005, March 11). Sharing research in health and physical education. Abstract presented to the School of Human Movement Studies, Queensland University of Technology (QUT). ?

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Adiabatic Behavior Of Strongly Nonlinear Internal Solitary Waves In Slope-Shelf Areas, V Vlasenko, L Ostrovsky, K Hutter Jan 2005

Adiabatic Behavior Of Strongly Nonlinear Internal Solitary Waves In Slope-Shelf Areas, V Vlasenko, L Ostrovsky, K Hutter

School of Biological and Marine Sciences

No abstract provided.

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Generation Of Secondary Internal Waves By The Interaction Of An Internal Solitary Wave With An Underwater Bank, Vasiliy Vlasenko, Werner Alpers Jan 2005

Generation Of Secondary Internal Waves By The Interaction Of An Internal Solitary Wave With An Underwater Bank, Vasiliy Vlasenko, Werner Alpers

School of Biological and Marine Sciences

No abstract provided.

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“In Search Of Subjectivity: An Irigarayan Reading Of The Body In Self-Representations Of Josephine Baker And Frida Kahlo.”, A Syska Jan 2005

“In Search Of Subjectivity: An Irigarayan Reading Of The Body In Self-Representations Of Josephine Baker And Frida Kahlo.”, A Syska

School of Law, Humanities and Social Sciences

No abstract provided.

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Quantifying Drug-Induced Dyskinesias In The Arms Using Digitised Spiral-Drawing Tasks, Xuguang Liu, Camille B. Carroll, Shou Yan Wang, John Zajicek, Peter G. Bain Jan 2005

Quantifying Drug-Induced Dyskinesias In The Arms Using Digitised Spiral-Drawing Tasks, Xuguang Liu, Camille B. Carroll, Shou Yan Wang, John Zajicek, Peter G. Bain

Peninsula Medical School

No abstract provided.

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The Correlation Grid: Analysis Of Synchronous Spiking In Multi-Dimensional Spike Train Data And Identification Of Feasible Connection Architectures, L Stuart, M Walter, R Borisyuk Jan 2005

The Correlation Grid: Analysis Of Synchronous Spiking In Multi-Dimensional Spike Train Data And Identification Of Feasible Connection Architectures, L Stuart, M Walter, R Borisyuk

School of Engineering, Computing and Mathematics

This paper presents a visualization technique specifically designed to support the analysis of synchronous firings in multiple, simultaneously recorded, spike trains. This technique, called the correlation grid, enables investigators to identify groups of spike trains, where each pair of spike trains has a high probability of generating spikes approximately simultaneously or within a constant time shift. Moreover, the correlation grid was developed to help solve the following reverse problem: identification of the connection architecture between spike train generating units, which may produce a spike train dataset similar to the one under analysis. To demonstrate the efficacy of this approach, results …

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The Effects Of Idea Elaboration On Unconscious Plagiarism, Louisa-Jayne Stark Jan 2005

The Effects Of Idea Elaboration On Unconscious Plagiarism, Louisa-Jayne Stark

School of Psychology Theses

Rates of unconscious plagiarism were investigated using Brown and Murphy's 3-stage paradigm. Initially, participants completed the creative Alternate Uses Test (generation phase) and then at test, recalled their original ideas (recall-own phase) and generated new ideas (generate-new phase). In both of the testing phases, participants plagiarised by reporting someone else's ideas as either their own idea or a new idea. Plagiarism rates increased over a one week retention interval (Experiment 2) and both active and passive participants were equally likely to plagiarise someone else's idea as a new idea (Experiment 1). When an elaboration phase was incorporated into the paradigm, …

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Determination Of Dissolved Iron Speciation In The North East Atlantic Ocean By Flow Injection Chemiluminescence, Simon Ussher Jan 2005

Determination Of Dissolved Iron Speciation In The North East Atlantic Ocean By Flow Injection Chemiluminescence, Simon Ussher

School of Geography, Earth and Environmental Sciences Theses

The knowledge of iron biogeochemistry is constrained by paucity in the understanding of its uptake, transport and the partitioning of the element between different phases, redox states and coordination sites. The work presented in this thesis describes the optimisation and evaluation of a Flow Injection Chemiluminescence (FICL) method for the shipboard determination of dissolved Fe(II) species (< 0.2 µm) in seawater. This includes results from two ship-board trials and a study of the effects of model ligands on iron redox speciation measurements in natural waters. The method was also used to determine the distribution of dissolved iron species (< 0.2 µm) in two contrasting study areas in the North East Atlantic Ocean and for a study of aerosol iron dissolution in seawater. The FI-CL method was evaluated and was found to be robust and sensitive, to have low limits o f detection (5-12 pM) and short analysis times 3 min) suitable for the high resolution spatial and temporal sampling required for shipboard analysis of Fe(II). A study of the effects of model ligands on Fe(II) determination revealed no conclusive evidence for significant interference from organic molecules on the method but Fe(III) in the presence of certain organic molecules had the potential to cause positive and negative interference in aqueous samples. Field survey results obtained for a transect between the Bay of Biscay to the coast of the Netherlands, showed enrichment of dissolved iron (0.7 - 2 nM) on the European continental shelf in March 2002. Near the shelf break, the iron enriched shelf waters were separated from low iron open ocean surface waters (0.15 - 0.4 nM) by a well-defined mixing gradient. Elevated dissolved Fe(II) concentrations (> 100 pM) were observed at the shelf break and during a solar radiation maximum in the coastal waters of the southern North Sea. These features were attributed to the dissolution of Fe(II) from anoxic sediments and photoreduction of iron from dissolved and suspended …

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Modelling The Water Quality Of The Patos Lagoon, Brazil, Deborah Ann Tyrrell Jan 2005

Modelling The Water Quality Of The Patos Lagoon, Brazil, Deborah Ann Tyrrell

School of Geography, Earth and Environmental Sciences Theses

A two-dimensional depth integrated finite element modelling suite comprising the flow model TELEN4AC-2D and the water quality model WQFLOW-2D has been calibrated to simulate the physics and chemistry of the Patos Lagoon and Estuary system in southern Brazil for the investigation of nutrients, primary production and faecal bacteria. The model has been evaluated for use as a predictive tool to aid the decision making process for the rehabilitation and management of the shallow embayment of Saco da Mangueira adjacent to the city of Rio Grande in the lower Patos Estuary. This bay is one of several shallow areas bordering the …

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Analysis Of Pharmaceuticals And Biomolecules Using Hplc Coupled To Icp-Ms And Esi-Ms, Andrew James Cartwright Jan 2005

Analysis Of Pharmaceuticals And Biomolecules Using Hplc Coupled To Icp-Ms And Esi-Ms, Andrew James Cartwright

School of Geography, Earth and Environmental Sciences Theses

The work described within this thesis explores the use of HPLC coupled with ICPMS and ESI-MS in order to develop novel methods which overcome specific analytical challenges in the pharmaceutical industry. A membrane desolvation interface has been evaluated for coupling high performance liquid chromatography (HPLC) with inductively coupled plasma mass spectrometry (ICP-MS). Desolvation of the sample prior to reaching the plasma was shown to facilitate a versatile coupling of the two instrumental techniques, enabling chromatographic eluents containing up to 100 % organic to be used. This interface also allowed gradient elution to be used with ICP-MS. Tris(2,4,6-trimethoxyphenyl)phosphonium propylamine bromide (TMPP) …

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Use Of Depth Perception For The Improved Understanding Of Hydrographic Data, Runar Ostnes Jan 2005

Use Of Depth Perception For The Improved Understanding Of Hydrographic Data, Runar Ostnes

School of Geography, Earth and Environmental Sciences Theses

This thesis has reviewed how increased depth perception can be used to increase the understanding of hydrographic data First visual cues and various visual displays and techniques were investigated. From this investigation 3D stereoscopic techniques prove to be superior in improving the depth perception and understanding of spatially related data and a further investigation on current 3D stereoscopic visualisation techniques was carried out. After reviewing how hydrographic data is currently visualised it was decided that the chromo stereoscopic visualisation technique is preferred to be used for further research on selected hydrographic data models. A novel chromo stereoscopic application was developed …

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Small Island Developing States, Sustainability And The Caribbean Sea, Asha Singh Jan 2005

Small Island Developing States, Sustainability And The Caribbean Sea, Asha Singh

School of Geography, Earth and Environmental Sciences Theses

This study encompasses twenty-seven SIDS and the Caribbean Sea. In order to detennine the pressure on the sea from anthropogenic activities both terrestrial and marine, four major components were investigated. These are (a) how land use activities on the islands are affecting the Sea (b) the effects of coastal and marine based activities on this marine area (c) the influences of natural events on the Caribbean Sea and the SIDS (d) how the region is responding to minimise the pressures on the sea via policies and programmes. In the first component, the DPSIR in combination with GIS was applied to …

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Landscapes Of Ephemeral Embrace : A Painter's Exploration Of Immersive Virtual Space As A Medium For Transforming Perception, Charlotte Adele Davies Jan 2005

Landscapes Of Ephemeral Embrace : A Painter's Exploration Of Immersive Virtual Space As A Medium For Transforming Perception, Charlotte Adele Davies

School of Engineering, Computing and Mathematics Theses

The following text has been written to illuminate the research embodied In Ephemere, a fullyimmersive virtual environment which integrates stereoscopic 3D computer-generated images and spatialized 3D sound, with a user interface based on breathing, balance, and gaze. This artwork was begun when I entered the doctoral program at CAiNA (Centre of Advanced Inquiry Into the Interactive Arts) in 1997, and was completed in 1998. The work Ephemere is grounded in a very personal vision, developed over more than 25 years of artistic practice, including, most significantly, painting. Ephemere follows on its predecessor Osmose, and as such, Is a continuation of …

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Re-Examining Scholarship: Exploring The Meanings Of Boyer's Dimensions To The Professoriate, Julia Craig Laker Jan 2005

Re-Examining Scholarship: Exploring The Meanings Of Boyer's Dimensions To The Professoriate, Julia Craig Laker

Plymouth Institute of Education Theses

Since Boyer's (1990) seminal publication on scholarship there has been a steadily expanding body of knowledge concerned with reviewing the priorities of the professoriate in higher education (HE). This dissertation enters that discourse by exploring HE educators' perceptions of Boyer's (1990) multiple dimensions of scholarship. It also accepts the challenge offered by Schon (1996) that examination of the new dimensions of scholarship requires a new epistemology by designing and employing a spiral methodology. This twofold task forms the basis of this dissertation. This investigation is contextually located in an education department in a large university in the United States of …

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Nursing Research In The National Health Service: Activity, Strategies And Organisational Models, Valerie Anne Woodward Jan 2005

Nursing Research In The National Health Service: Activity, Strategies And Organisational Models, Valerie Anne Woodward

School of Nursing and Midwifery Theses

In this study, nursing research activity and support for this within the English National Health Service (NHS) were examined. The study was carried out in two phases. The first phase involved. working with one acute NHS trust to identify nursing research activity in the trust and to develop its nursing research strategy. The second involved working with five NHS trusts to explore nursing research activity and analyse support for nursing research within these organisations. The professional, educational and policy-related issues that set the context for the study were examined. The literature review for Phase 1 highlighted the fact that there …

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