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Drug-Resistant Epilepsy And Ketogenic Diet Therapy – A Qualitative Study Of Families’ Experiences, Jennifer H. Carroll, Tracey Parkin, J. Helen Cross, Mary Hickson, Emma Williams, Val Aldridge, Avril Collinson Jan 2024

Drug-Resistant Epilepsy And Ketogenic Diet Therapy – A Qualitative Study Of Families’ Experiences, Jennifer H. Carroll, Tracey Parkin, J. Helen Cross, Mary Hickson, Emma Williams, Val Aldridge, Avril Collinson

School of Health Professions

Background: A diagnosis of drug-resistant epilepsy is life changing for a family. Ketogenic diet therapy (KDT) can offer hope when other treatments have failed. However, it often requires a significant change in daily routine and dietary habits. This qualitative descriptive study aimed to explore families’ experiences of epilepsy and KDT. Methods: Parents of a child aged ≤18 years with epilepsy, currently or recently treated with KDT, were recruited from the UK and internationally via UK Ketogenic Diet (KD) centres, charities, and social media. Semi-structured interviews were audio recorded, transcribed verbatim, anonymised, coded using Nvivo (V12), and inductive thematic analysis undertaken. …


Beyond Surgery: Navigating Postoperative Care For Cauda Equina Syndrome Through A Scoping Review, Krithika Anil, Sandra Olmesdahl, Jack Read, Sam Hughes, Marcus Drake, Ingrid Hoeritzauer, Julie Woodfield, Holly Roy Jan 2024

Beyond Surgery: Navigating Postoperative Care For Cauda Equina Syndrome Through A Scoping Review, Krithika Anil, Sandra Olmesdahl, Jack Read, Sam Hughes, Marcus Drake, Ingrid Hoeritzauer, Julie Woodfield, Holly Roy

School of Health Professions

Objective: Cauda equina syndrome (CES) is a serious neurological injury that can result in permanent disability. Our objective was to review the evidence for rehabilitation strategies for CES in a scoping review.Methods: A scoping review of the literature to identify rehabilitation strategies and their outcomes was performed. The search strategy used was: (Cauda equina syndrome) AND (treatment OR management OR intervention OR physio* OR bladder* OR neuro* OR stem cell OR repair OR rehab*) AND ("post?operat* OR post?surgical OR surgery"). MEDLINE, CINHAL, Prospero, Cochrane, ClinicalTrials.gov, EMBASE, Web of Science, PEDro, and eThos were searched.Results: Eight studies of rehabilitation for CES …


Exploring Parents’ And Teachers’ Experience Of A Novel Programme: Safe With Schools [Swis] – A Systemic Attachment-Based Approach For Caregivers Of Autistic Children, Tara Vassallo Jan 2024

Exploring Parents’ And Teachers’ Experience Of A Novel Programme: Safe With Schools [Swis] – A Systemic Attachment-Based Approach For Caregivers Of Autistic Children, Tara Vassallo

School of Law, Humanities and Social Sciences Theses

This research explored the experience of thirty-two parents and teachers of autistic children, from nine schools in the southwest of England participating in a novel systemic attachment-based programme SAFE with Schools (SwiS). Designed as a competency-based framework with a non-blaming approach using established techniques and activities drawn from systemic family therapy, the SwiS programme was employed to engage parents and teachers experiencing autism-related difficulties. The aim was to explore their experience of SwiS and in turn how these caregivers made meaning of autism through the systemic attachment-focus of SwiS, what it revealed about the nature of the parent-teacher-child system, and …


The Role Played By Non-Formal Education In The Lives Of Iraqi-British Citizens: A Study Of Three Iraqi-British Cultural Institutions And How Non-Formal Education Empowers Individuals And Communities, Nadeem Al-Abdalla Jan 2024

The Role Played By Non-Formal Education In The Lives Of Iraqi-British Citizens: A Study Of Three Iraqi-British Cultural Institutions And How Non-Formal Education Empowers Individuals And Communities, Nadeem Al-Abdalla

School of Law, Humanities and Social Sciences Theses

This thesis highlights the role played by non-formal education in the lives of Iraqi community members who participate in the activities offered by London’s Iraqi-British cultural centres. The key aims of this thesis were; to research, document and analyse London’s Iraqi community and their experiences of non-formal learning within Iraqi cultural centres; and to establish the extent to which they found their participation in this non-formal learning empowering, both at an individual and community level. Many studies have been conducted into the lives of newly arrived communities. Generally, these studies tend to focus on their early years in the UK …


How Does Living In A Rural Location Affect Experiences Of Acquired Vision Impairment?, Rebecca Woods Jan 2024

How Does Living In A Rural Location Affect Experiences Of Acquired Vision Impairment?, Rebecca Woods

School of Law, Humanities and Social Sciences Theses

This research explores the lived experiences of adults with acquired sight loss who live in rural areas in Southwest England. There is a scarcity of published academic research with this group. Vision impaired people who live in rural locations are therefore unrecognised sources of vision impairment rehabilitation knowledge. The research is conducted in an interpretivist paradigm. The research is guided by phenomenological understanding, rooted in Merleau-Ponty’s concepts of perception, the centrality of tool-use, and human embodiment. Attention is centred on the process of adapting to sight loss in a domestic setting, placing this research in an experiential, community-based educational context. …


University Sustainability In Times Of Uncertainty: The Impact Of Brexit On Eu Staff And Students, Diane Stanley Jan 2024

University Sustainability In Times Of Uncertainty: The Impact Of Brexit On Eu Staff And Students, Diane Stanley

School of Law, Humanities and Social Sciences Theses

The Brexit referendum in June 2016, which led to the UK’s decision to leave the European Union (EU), generated significant concern and anxiety within the United Kingdom's (UK) Higher Education (HE) sector. The potential impact on EU student and staff recruitment, EU research funding, and collaborations with Europe was uncertain, as many Brexit policies and procedures had not been considered by the government when the Leave outcome was announced. EU staff and students working and studying in UK Higher Education Institutions (HEIs) were left contemplating their future in the UK. This thesis examines the impact of Brexit through Charles Wright …


Collaboration In Higher Education: Theorising Co-Creation For Inclusive Learning And Teaching Praxis, Sandra Abegglen Jan 2024

Collaboration In Higher Education: Theorising Co-Creation For Inclusive Learning And Teaching Praxis, Sandra Abegglen

School of Law, Humanities and Social Sciences Theses

In the last ten years UK Higher Education has undergone radical processes of reconstruction by focusing on output and value for money, thereby reinforcing the myth of meritocracy. Together with still prevalent notions of developmental learning and pyramidical teaching, this has heightened a culture of individualism. Despite an ostensible emphasis on partnership, isolation and ‘silo-isation’ are evident today with lecturers and students experiencing increased pressure to produce and perform alone, leading to little time for thinking and doing together. This situation was exacerbated by COVID-19 with social distancing measures and remote instruction, which have further increased workloads and loneliness, accompanied …


Practical Actions To Strengthen Capacity For Deep-Water Research In Africa, Kirsty A Mcquaid, Kerry Howell, Agnes W.N. Muthumbi, Olusola Adeoye, Isa Elegbede, Luther Adams, Blessing Charuka, Ana Hilário, Hendrina Kadila, Sophia Laarissa, Randa Mejri, Sidi Mohamed, Damaris Mutia, Angela Nyangwe, Angus Paterson, Sinothando Shibe, Kerry Sink, Sheena Talma, Urias Taylor, Arthur Tuda Jan 2024

Practical Actions To Strengthen Capacity For Deep-Water Research In Africa, Kirsty A Mcquaid, Kerry Howell, Agnes W.N. Muthumbi, Olusola Adeoye, Isa Elegbede, Luther Adams, Blessing Charuka, Ana Hilário, Hendrina Kadila, Sophia Laarissa, Randa Mejri, Sidi Mohamed, Damaris Mutia, Angela Nyangwe, Angus Paterson, Sinothando Shibe, Kerry Sink, Sheena Talma, Urias Taylor, Arthur Tuda

School of Biological and Marine Sciences

While Africa's deep marine biodiversity offers economic prospects it also supports crucial ecosystem services and sustainable development is dependent on knowledge of these systems. Building understanding of deep-water ecosystems is key, but there are substantial discrepancies in countries' abilities to achieve this. Coinciding with the 2024 Ocean Decade Conference, the Challenger 150 African Network of Deep-water Researchers is pleased to release a report on “Practical Actions to Strengthen Capacity for Deep-water Research in Africa”. Through a series of online workshops, the ANDR brought together 98 individuals from 19 African nations to discuss challenges for deep-water research in Africa, identify solutions …


Gendered Violence And Sexualized Representations In Video Games: (Lack Of) Effect On Gender-Related Attitudes, Liam Cross, Linda K. Kaye, Juris Savostijanovs, Neil Mclatchie, Matthew Johnston, Liam Whiteman, Robyn Mooney, Gray Atherton Jan 2024

Gendered Violence And Sexualized Representations In Video Games: (Lack Of) Effect On Gender-Related Attitudes, Liam Cross, Linda K. Kaye, Juris Savostijanovs, Neil Mclatchie, Matthew Johnston, Liam Whiteman, Robyn Mooney, Gray Atherton

School of Psychology

This research explored how gender portrayals in video games affect gender-related attitudes. Two hundred participants from the United Kingdom and Malaysia participated across three experiments, where the appearance and behaviour of video game characters were manipulated with regard to target (enemy) gender (Study 1), sexually explicit attire (Study 2) and level of character agency (Study 3). We found minimal evidence that exposure to gender-stereotyped content resulted in differential gender-related attitudes (implicit associations, hostile and benevolent sexism, or rape myth acceptance). However, Study 1 findings showed that individuals who played a first-person shooter with male enemies showed lower endorsement of some …


Community-Based Respiratory Health Measures In Children And Young People With Cerebral Palsy: A Scoping Review, Rachel Knight Lozano, Harriet Shannon, Jonathan Gilby, Sian Goddard, Leanne Turner, Jonathan Marsden Jan 2024

Community-Based Respiratory Health Measures In Children And Young People With Cerebral Palsy: A Scoping Review, Rachel Knight Lozano, Harriet Shannon, Jonathan Gilby, Sian Goddard, Leanne Turner, Jonathan Marsden

School of Health Professions

Aim: To identify, map, and describe outcome measurement domains and instruments used within a community setting to assess respiratory health in children and young people aged 1 to 18 years, diagnosed with cerebral palsy (CP). Method: A scoping review methodology informed structured searches in nine databases, grey literature, and registries, conducted in August 2021 (updated in February 2023). Articles were screened for eligibility by two independent researchers. Any outcome measurement instruments used to assess respiratory health or associated impact were extracted, categorized, and mapped to health and health-related domains of the International Classification of Functioning, Disability, and Health. Results: Seventy-six …


Tackling Loneliness Together: A Three-Tier Social Identity Framework For Social Prescribing, S. Alexander Haslam, Catherine Haslam, Tegan Cruwys, Leah S. Sharman, Shaun Hayes, Zoe Walter, Jolanda Jetten, Niklas K. Steffens, Magnolia Cardona, Crystal J. La Rue, Niamh Mcnamara, Blerina Këllezi, Juliet R.H. Wakefield, Clifford Stevenson, Mhairi Bowe, Peter Mcevoy, Alysia M. Robertson, Mark Tarrant, Genevieve Dingle, Tarli Young Jan 2024

Tackling Loneliness Together: A Three-Tier Social Identity Framework For Social Prescribing, S. Alexander Haslam, Catherine Haslam, Tegan Cruwys, Leah S. Sharman, Shaun Hayes, Zoe Walter, Jolanda Jetten, Niklas K. Steffens, Magnolia Cardona, Crystal J. La Rue, Niamh Mcnamara, Blerina Këllezi, Juliet R.H. Wakefield, Clifford Stevenson, Mhairi Bowe, Peter Mcevoy, Alysia M. Robertson, Mark Tarrant, Genevieve Dingle, Tarli Young

School of Psychology

In recent years, there has been growing recognition of the threats to health posed by loneliness. One of the main strategies that has been recommended to address this is social prescribing (SP). This typically involves general practitioners (GPs) and other health practitioners directing clients who are experiencing loneliness and related conditions to take part in social activities—typically in recreational and community contexts. However, evidence for the effectiveness of SP is mixed—leading some to suggest that enthusiasm for it might be misplaced. In this review, we argue that a core problem with most existing approaches to SP is that they lack …


One Hundred Years Of Eeg For Brain And Behaviour Research, Faisal Mushtaq, Dominik Welke, Anne Gallagher, Yuri G Pavlov, Layla Kouara, Jorge Bosch-Bayard, Jasper J F Van Den Bosch, Mahnaz Arvaneh, Amy R Bland, Maximilien Chaumon, Cornelius Borck, Xun He, Steven J Luck, Maro G Machizawa, Cyril Pernet, Aina Puce, Sidney J Segalowitz, Christine Rogers, Muhammad Awais, Claudio Babiloni, Neil W Bailey, Sylvain Baillet, Robert C A Bendall, Daniel Brady, Maria L Bringas-Vega, Niko A Busch, Ana Calzada-Reyes, Armand Chatard, Peter E Clayson, Michael X Cohen Jan 2024

One Hundred Years Of Eeg For Brain And Behaviour Research, Faisal Mushtaq, Dominik Welke, Anne Gallagher, Yuri G Pavlov, Layla Kouara, Jorge Bosch-Bayard, Jasper J F Van Den Bosch, Mahnaz Arvaneh, Amy R Bland, Maximilien Chaumon, Cornelius Borck, Xun He, Steven J Luck, Maro G Machizawa, Cyril Pernet, Aina Puce, Sidney J Segalowitz, Christine Rogers, Muhammad Awais, Claudio Babiloni, Neil W Bailey, Sylvain Baillet, Robert C A Bendall, Daniel Brady, Maria L Bringas-Vega, Niko A Busch, Ana Calzada-Reyes, Armand Chatard, Peter E Clayson, Michael X Cohen

School of Psychology

On the centenary of the first human EEG recording, more than 500 experts reflect on the impact that this discovery has had on our understanding of the brain and behaviour. We document their priorities and call for collective action focusing on validity, democratization and responsibility to realize the potential of EEG in science and society over the next 100 years.


Benchmarking Usability Of Patient Portals In Estonia, Finland, Norway, And Sweden, Sari Kujala, Saija Simola, Bo Wang, Hedvig Soone, Josefin Hagström, Annika Bärkås, Iiris Hörhammer, Åsa Cajander, Asbjørn Johansen Fagerlund, Bridget Kane, Anna Kharko, Eli Kristiansen, Jonas Moll, Hanife Rexphepi, Maria Hägglund, Monika A. Johansen Jan 2024

Benchmarking Usability Of Patient Portals In Estonia, Finland, Norway, And Sweden, Sari Kujala, Saija Simola, Bo Wang, Hedvig Soone, Josefin Hagström, Annika Bärkås, Iiris Hörhammer, Åsa Cajander, Asbjørn Johansen Fagerlund, Bridget Kane, Anna Kharko, Eli Kristiansen, Jonas Moll, Hanife Rexphepi, Maria Hägglund, Monika A. Johansen

School of Psychology

Introduction: Poor usability is a barrier to widespread adoption of electronic health records (EHR). Providing good usability is especially challenging in the health care context, as there is a wide variety of patient users. Usability benchmarking is an approach for improving usability by evaluating and comparing the strength and weaknesses of systems. The main purpose of this study is to benchmark usability of patient portals across countries. Methods: A mixed-methods survey approach was applied to benchmark the national patient portals offering patient access to EHR in Estonia, Finland, Norway, and Sweden. These Nordic countries have similar public healthcare systems, and …


Optimizing Group Work Strategies In Virtual Dissection, Lily Evans, Lauren Singer, Daniel Zahra, Ifeoluwa Agbeja, Siobhan M. Moyes Jan 2024

Optimizing Group Work Strategies In Virtual Dissection, Lily Evans, Lauren Singer, Daniel Zahra, Ifeoluwa Agbeja, Siobhan M. Moyes

Peninsula Medical School

Due to its haptic and interactive nature, virtual anatomy provides an opportunity for small-group learning, enabling students to develop their group work skills before they graduate. However, there is currently little practical guidance supported by pedagogic principles detailing how to incorporate it into curricula. Anatomy educators at the University of Plymouth conducted action research aiming to capture students' overall perceptions of the virtual anatomy platform Anatomage. Questioning the benefits and challenges students face while interacting with Anatomage prompted the creation of evidence-based interventions to be later evaluated. Although a plethora of themes were identified, this report specifically examines those relating …


A Novel Approach To Expedite Emergency Investigation For Suspected Cauda Equina Syndrome Referrals From Community And Primary Care Services: A Service Evaluation, Jonathon Gill, Sue Greenhalgh, Jos M. Latour, Stephen Pickup, Gillian Yeowell Jan 2024

A Novel Approach To Expedite Emergency Investigation For Suspected Cauda Equina Syndrome Referrals From Community And Primary Care Services: A Service Evaluation, Jonathon Gill, Sue Greenhalgh, Jos M. Latour, Stephen Pickup, Gillian Yeowell

School of Nursing and Midwifery

Introduction: Although a rare spinal emergency, cauda equina syndrome (CES) can result in significant physical, emotional, and psychological sequalae. Introducing a CES pathway enhances diagnosis but may increase Radiology and Orthopaedic workload. To address this, one NHS hospital in England introduced a novel CES pathway. Utilising a criteria-led pathway, patients were referred directly from community/primary care, via the Emergency Department, for an emergency MRI scan. Objective: To compare the outcomes of patients referred via an original and redesigned Community and Primary Care CES pathway. Design: A retrospective service evaluation was undertaken of all emergency MRI scans investigating suspected CES via …


Addressing Digital Exclusion Via The Inter-Generational Codesign Of Extended Reality, Underwater Telepresence, Social Games, And Voice Ai Technologies, Ray Jones, Rory Baxter, Marius Varga, Oksana Hagen, Amir Aly, Dena Bazazian, Alejandro Veliz Reyes, Swen Gaudl Jan 2024

Addressing Digital Exclusion Via The Inter-Generational Codesign Of Extended Reality, Underwater Telepresence, Social Games, And Voice Ai Technologies, Ray Jones, Rory Baxter, Marius Varga, Oksana Hagen, Amir Aly, Dena Bazazian, Alejandro Veliz Reyes, Swen Gaudl

School of Nursing and Midwifery

Addressing Digital Exclusion via the Inter-Generational Codesign of Extended Reality, Underwater Telepresence, Social Games, and Voice AI Technologies


Training Needs For Staff Providing Remote Services In General Practice: A Mixed-Methods Study, Trisha Greenhalgh, Rebecca Payne, Nina Hemmings, Helen Leach, Isabel Hanson, Anwar Khan, Lisa Miller, Emma Ladds, Aileen Clarke, Sara E. Shaw, Francesca Dakin, Sietse Wieringa, Sarah Rybczynska-Bunt, Stuart D. Faulkner, Richard Byng, Asli Kalin, Lucy Moore, Joseph Wherton, Laiba Husain, Rebecca Rosen Jan 2024

Training Needs For Staff Providing Remote Services In General Practice: A Mixed-Methods Study, Trisha Greenhalgh, Rebecca Payne, Nina Hemmings, Helen Leach, Isabel Hanson, Anwar Khan, Lisa Miller, Emma Ladds, Aileen Clarke, Sara E. Shaw, Francesca Dakin, Sietse Wieringa, Sarah Rybczynska-Bunt, Stuart D. Faulkner, Richard Byng, Asli Kalin, Lucy Moore, Joseph Wherton, Laiba Husain, Rebecca Rosen

Peninsula Medical School

Background Contemporary general practice includes many kinds of remote encounter. The rise in telephone, video and online modalities for triage and clinical care requires clinicians and support staff to be trained, both individually and as teams, but evidence-based competencies have not previously been produced for general practice. Aim To identify training needs, core competencies, and learning methods for staff providing remote encounters. Design and setting Mixed-methods study in UK general practice. Method Data were collated from longitudinal ethnographic case studies of 12 general practices; a multi-stakeholder workshop; interviews with policymakers, training providers, and trainees; published research; and grey literature (such …


Inconsistent Bioreceptivity Of Three Mortar Mixes In Subtidal Sites, Jessica R. Bone, Alice E. Hall, Rick Stafford, Roger J.H. Herbert Jan 2024

Inconsistent Bioreceptivity Of Three Mortar Mixes In Subtidal Sites, Jessica R. Bone, Alice E. Hall, Rick Stafford, Roger J.H. Herbert

School of Biological and Marine Sciences

Concrete is extensively used in coastal engineering and development which, in addition to its high carbon footprint, threatens intertidal habitats and ecosystems. Eco-engineering addresses this by designing habitat features into coastal infrastructure. The chemical bioreceptivity of cement has been shown to vary, but ordinary Portland cement is generally considered to be the least bioreceptive. In this study, we compare two low carbon mortars (a natural, single source cement (VP), and an ordinary Portland cement/ ground granulated blast furnace slag blend (GGBS)) with an ordinary Portland cement-based control mix (OPC). The three mortars were made into smooth blocks which were secured …


Do I Sound Anxious? Emotional Arousal Is Linked To Changes In Vocalisations In Domestic Chicks (Gallus Gallus Dom.), Sarah A. Collins, Katherine Herborn, Kenneth J. Sufka, Lucy Asher, Ben Brilot Jan 2024

Do I Sound Anxious? Emotional Arousal Is Linked To Changes In Vocalisations In Domestic Chicks (Gallus Gallus Dom.), Sarah A. Collins, Katherine Herborn, Kenneth J. Sufka, Lucy Asher, Ben Brilot

School of Biological and Marine Sciences

A major goal in animal welfare science is the development of methods that quantify or ‘read-out’ current affective states in freely behaving animals. In mammalian models, changes in acoustic parameters within vocalisations have been linked to differences in emotional arousal, although there are very few studies showing changes in vocalisations that act as indicators of valence (positive or negative affect). Currently, there are very few studies on vocal indicators of emotion in birds. To determine the link between acoustic parameters within vocalisations and emotion in domestic chicks (Gallus gallus dom.), we used a well-validated paradigm that purports to elicit two …


Secure Container-Based High Performance Computing Architecture , Holger Gantikow Jan 2024

Secure Container-Based High Performance Computing Architecture , Holger Gantikow

School of Engineering, Computing and Mathematics Theses

This PhD thesis addresses the evolving landscape of High Performance Computing (HPC) by focusing on the critical challenge of securing the use of container virtualisation within HPC environments. The traditional approach to security for HPC operators is being challenged by a growing number of cyber security threats such as hacks and resource misuse. In addition, the risk of insider attacks is increasing, overall requiring a re-evaluation of security strategies, which in many cases are still based on a high level of trust in users.This is further aggravated by the increasing demand to open up HPC environments to novel users and …


Enhancing Pitch Stability In Floating Wind Platforms: The Hydrodynamic Effects Of Thin Plates, Ignacio Pregnan Johannesen Jan 2024

Enhancing Pitch Stability In Floating Wind Platforms: The Hydrodynamic Effects Of Thin Plates, Ignacio Pregnan Johannesen

School of Engineering, Computing and Mathematics Theses

The Floating Offshore Wind Turbines (FOWT) technology is still at an early stage looking for ways to make it competitive. In the case of semi-submersible FOWT the large structure has been pointed as an option to tackle the final energy price and therefore, smaller/cheaper platforms are desired. However, this would have implications on the platform hydrodynamic performance. This thesis discusses the use of thin disks as pitch motion suppression surfaces for FOWT platforms, employing three methodologies; potential flow, Computational Fluid Dynamics (CFD) and Experiments. With NEMOH a boundary element method code, the added mass and excitation forces/moments were calculated for …


Data Security And User Authentication In Public Cloud Computing Environments, Nelson Vasconcelos Soares Dos Santos Jan 2024

Data Security And User Authentication In Public Cloud Computing Environments, Nelson Vasconcelos Soares Dos Santos

School of Engineering, Computing and Mathematics Theses

Cloud computing has become a prevalent paradigm for organisations and individuals, offering a range of services and resources that enable the efficient management, processing and storage of large quantities of data. However, despite its numerous advantages, cloud computing also presents significant challenges related to data security and user authentication. The distributed nature of cloud environments, coupled with the relinquishment of control over data to cloud service providers, has raised concerns regarding data vulnerability to various types of attacks, such as data breaches, malware injection, and denial of service. Moreover, traditional password and token-based authentication methods have been shown to be …


The Assessment Of Floating Offshore Wind Turbines In Extreme Conditions, Andre Onife Alwyn White Jan 2024

The Assessment Of Floating Offshore Wind Turbines In Extreme Conditions, Andre Onife Alwyn White

School of Engineering, Computing and Mathematics Theses

The purpose of this research is to assess if a floating offshore wind turbine (FOWT) system that is suitable for the environmental conditions in the Scottish North Sea (SNS) is also suitable for the environmental conditions in the Jamaica Caribbean Sea (JCS). A FOWT within Jamaica is an important structure because it produces renewable energy which helps to reduce the dependence on fossil fuel as the primary source of energy. At the same time, it also contributes to reducing global warming caused by climate change effects. These structures, therefore, must be robust enough to withstand the most extreme environmental conditions …


Social Prescribing For Autistic Adults, Charlotte Featherstone Jan 2024

Social Prescribing For Autistic Adults, Charlotte Featherstone

Peninsula Medical School Theses

Background Autistic adults are affected by health and social disparities that impact life expectancy and quality of life, frequently resulting in escalating wellbeing concerns requiring costly acute care. Evidence suggests barriers to healthcare and a lack of post-diagnostic support may contribute to these inequalities. Social prescribing, a low-intensity personalised care model receiving increasing attention from policymakers and commissioners, offers opportunities to address isolation, build skills and promote health through collaborations between services and communities. However, social prescribing research and provision has overlooked wellbeing and access needs of autistic adults. This PhD project aimed to investigate factors affecting accessibility of social …


Pancreatoduodenectomy For Malignancy: Factors Influencing Surgical And Oncological Outcomes, Thomas Brendon Russell Jan 2024

Pancreatoduodenectomy For Malignancy: Factors Influencing Surgical And Oncological Outcomes, Thomas Brendon Russell

Peninsula Medical School Theses

Introduction: Fit patients with a resectable pancreatic head adenocarcinoma (PDAC), ampullary adenocarcinoma (AA) or distal cholangiocarcinoma (CC) may be offered pancreatoduodenectomy (PD) with curative-intent. However, perioperative morbidity and cancer recurrence rates are high. This thesis aimed to explore the factors influencing PD outcomes. A focus was placed on nutrition, postoperative complications, and recurrence in AA patients. It is hoped the findings will guide patient selection/consenting and have implications for patient management. Methods: A retrospective cohort study of patients who underwent PD for histologically-confirmed malignancy was carried out (2012-2015). Twenty-nine centres from eight countries were involved. Data on the following were …


Failure, Remediation And The Disruption Of Professional Identity Formation In Undergraduate Medical Students (At Two Uk Medical Schools), James Michael Read Jan 2024

Failure, Remediation And The Disruption Of Professional Identity Formation In Undergraduate Medical Students (At Two Uk Medical Schools), James Michael Read

Peninsula Medical School Theses

The aim of this thesis is to understand how the narratives medical students create around their professional identities are impacted upon by academic failure and subsequent remediation at two UK medical schools. Whilst much has been written regarding pedagogically underpinned approaches to remediation, little has been published regarding how these interventions impact on the ways that students perceive themselves as future doctors, and the implications this has on their future studies. This thesis asks how failure and subsequent remediation impacts on professional identity formation, explores the different identities that students narrate they hold and considers how these findings can be …


Epigenetic Regulation Of Inflammatory Pathways In Alcohol Related Hepatitis, Huey Kuan Tan Jan 2024

Epigenetic Regulation Of Inflammatory Pathways In Alcohol Related Hepatitis, Huey Kuan Tan

Peninsula Medical School Theses

Background: Alcohol-related liver disease (ArLD) contributes to approximately 1% of deaths worldwide and impacts on both economy and healthcare system. Alcohol related hepatitis (AH) - phenomenon of ArLD which is characterised by overactive inflammation is associated with 30% mortality rate at 90 days. Glucocorticoids (GC) are commonly used to treat AH. However, more than 1 in 3 patients fail to respond to GC therapy. Within the GC responders, the efficacy is variable due to individual glucocorticoid resistance. Improving our comprehension of GC non-responsiveness/ resistance is critical for early stratification of these patients and development of alternative therapies. This piece of …


Navigating The Complexity Of Applying Nutrition Evidence To Individualised Care: Summary Of An Academy Of Nutrition Sciences Position Paper, Judith Buttriss, Mary Hickson, Kevin Whelan, Christine Williams Jan 2024

Navigating The Complexity Of Applying Nutrition Evidence To Individualised Care: Summary Of An Academy Of Nutrition Sciences Position Paper, Judith Buttriss, Mary Hickson, Kevin Whelan, Christine Williams

School of Health Professions

Diet is key to the maintenance of health and crucial in the prevention and management of many diseases. Modified nutrient intake may become essential to prevent deficiency, optimise development and health or manage symptoms and disease progression. Adding to the complexity, disease and its treatment can also affect taste, appetite and ability to access and prepare foods. Coupled with this, individual requirements for energy, macronutrients and micronutrients are influenced by factors such as life stage (age, growth, pregnancy, etc.) and health status, which can affect the processes of consuming, digesting, absorbing, metabolising or excreting nutrients. First and foremost, dietary advice …


Brittle-Viscous Deformation Cycles At The Base Of The Seismogenic Zone In The Continental Crust, Francesca Prando Jan 2024

Brittle-Viscous Deformation Cycles At The Base Of The Seismogenic Zone In The Continental Crust, Francesca Prando

School of Geography, Earth and Environmental Sciences Theses

The main goal of the study was to determine the dynamical cycle of ductile-brittle deformation and to characterise the fluid pathways at different scales of a brittle-viscous fault zone active at the base of the seismogenic crust. Object of analysis are samples from the sinistral strike-slip fault zone BFZ045 from Olkiluoto (SW Finland), located at the site of a deep geological repository for nuclear waste. Combined microstructural analysis, electron backscatter diffraction (EBSD), and mineral chemistry were applied to reconstruct the variations in pressure, temperature, fluid pressure, and differential stress that mediated deformation and strain localization along BFZ045 across the BDTZ. …


Sofa-Surfing: The Cartographies Of Young People Utilising Host-Dependent Shelter., Kieran Green Jan 2024

Sofa-Surfing: The Cartographies Of Young People Utilising Host-Dependent Shelter., Kieran Green

School of Geography, Earth and Environmental Sciences Theses

In 2016, 35% of UK young people (16-25 years) reported having sofa-surfed in the past. Past research highlights that spaces where people sofa-surfing stay are often tenuous, short-lived and worsen over time, reducing mental health, educational attainment, and the ability to find work (McLoughlin, 2013; Albanese et al., 2018). However, a study has not elucidated how young people’s preferences, identities, experiences, and access to support create highly varied sofa-surfing geographies and outcomes. This study examined young people's different geographical experiences and outcomes of sofa-surfing. Specifically, I outline key sofa-surfing experiences centred on uses of space, mobility, and identity (cartographies) and …