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Articles 991 - 1020 of 16362
Full-Text Articles in Entire DC Network
Comparison Of Urethral Bulking Injection Therapy And Surgical Midurethral Sling Placement For Treatment Of Stress Urinary Incontinence In Women, Ashley Black
Physician Assistant Scholarly Project Papers
This literature review aims to assess the comparative efficacy and safety of urethral bulking injection therapy and surgical midurethral sling intervention in the treatment of stress incontinence in women. A comprehensive search of the existing literature was conducted and includes studies from PubMed, an electronic search databases. The findings indicate that both urethral bulking injection therapy and surgical midurethral sling intervention are suitable interventions to be considered for the treatment of stress incontinence in women. Current research available regarding the efficacy of urethral bulking agents versus midurethral slings suggests that the placement of a miduerthral sling has the highest incidence …
Liraglutide Versus Semaglutide: Long Term Weight Loss Management In Obese Individuals, Mckenzie Burke
Liraglutide Versus Semaglutide: Long Term Weight Loss Management In Obese Individuals, Mckenzie Burke
Physician Assistant Scholarly Project Papers
Obesity has been a source of complications affecting multiple aspects from a physiological and psychological standpoint which has been steadily growing. There are a multitude of weight loss programs and medications with the idea of sustaining consistent weight loss to include use of the pharmaceuticals discussed within this review. The purpose of this literature review is to compare the efficacy and safety with use of liraglutide versus semaglutide (GLP-1 receptor agonists) in respect to long term weight loss management while in conjunction to lifestyle modifications within the obese population. Thorough research has been done with the aid of health science …
The Effectiveness Of The Gut-Brain-Axis Versus Ssri For Treatment And Management Of Depression, Jenni Hetletved
The Effectiveness Of The Gut-Brain-Axis Versus Ssri For Treatment And Management Of Depression, Jenni Hetletved
Physician Assistant Scholarly Project Papers
Major Depressive Disorder (MDD) is a crippling condition that affects millions of people worldwide. Serotonin reuptake inhibitors (SSRIs) are the staple treatment adjunct to psychotherapy. Recently, the connection between gut health, specifically the gut brain axis, has been researched to look at the connection between gut microbiota and it’s effect on depressive symptoms. A literature review was performed using electronic databases such as PubMed, PsychINFO, and embase. This meta-analysis evaluates the connection between gut microbiota and depression as well as the effectiveness of SSRI therapy on depression. Results show a significant change in gut microbiota with short term change to …
Efficacy Of Transcutaneous Electrical Nerve Stimulation Vs. Calcitonin Gene Related Peptides In The Application Of Migraine Prophylaxis, Matthew Davis
Efficacy Of Transcutaneous Electrical Nerve Stimulation Vs. Calcitonin Gene Related Peptides In The Application Of Migraine Prophylaxis, Matthew Davis
Physician Assistant Scholarly Project Papers
Worldwide migraines affect millions of people everyday causing significant impact on patient’s lives. Oftentimes, these patients have failed several first-line therapies for migraine prophylaxis causing pharmaceutical companies to develop newer therapies. The purpose of this systematic literature review is to evaluate the effectiveness and tolerability of transcutaneous electrical nerve stimulator (TENS) devices versus calcitonin gene related peptide (CGRP) antagonists in the application of migraine prophylaxis. PubMed and ClinicalKey were searched with key terms, 17 sources were selected that were published after 2016. Sources included meta-analysis, literature review, and randomized control trials. The data showed that TENS devices as well as …
Active Toxoplasmosis Infection: Efficacy And Safety Of Treatment Options, Daniele Krouse
Active Toxoplasmosis Infection: Efficacy And Safety Of Treatment Options, Daniele Krouse
Physician Assistant Scholarly Project Papers
This literature review intends to investigate the safety and efficacy of two different drug treatment regimens, pyrimethamine versus trimethoprim-sulfamethoxazole, for active toxoplasmosis infections. Affecting nearly 11% of the United States population and up to 80% of the populations of tropical countries, Toxoplasmosis infection is the second leading cause of death from food borne illness. Current classic management of active infection with pyrimethamine is correlated with numerous undesirable side effects, high cost and need for complex use of adjunctive medications. It is necessary to identify alternative treatment options with fewer side effects, less complex regimens, lower cost, and easier access for …
Associations Between Screen Use And Depression In The Youth Population, David Franta
Associations Between Screen Use And Depression In The Youth Population, David Franta
Physician Assistant Scholarly Project Papers
The association between depression in the youth population and screen use has remained largely unclear. Depression is a common finding in children and adolescents, and as mobile phones, computers, and television are becoming more readily available to young populations, evaluation of the relationship between the two could likely be very important. Unfortunately, little concrete evidence has been established regarding the direct effects of screen time and the presence or development of depression. A literature review comprised of both cross-sectional and longitudinal studies was performed to evaluate the current literature regarding screen use and depression in the youth population, including differences …
Cognitive Behavior Therapy Versus Internet Cognitive Behavior Therapy In Adults With Anxiety Or Depression, Heather Greenwood
Cognitive Behavior Therapy Versus Internet Cognitive Behavior Therapy In Adults With Anxiety Or Depression, Heather Greenwood
Physician Assistant Scholarly Project Papers
According to the American Psychiatric Association, the prevalence of anxiety and depression in adults in their lifetime are nearly 30% and 16.6% respectively. The combination of pharmacotherapy and psychotherapy interventions (including talk therapy or cognitive behavior therapy (CBT)) are considered best practice, but in recent years there has been an increase in the popularity of applications and web-based services categorized as “internet cognitive behavior therapy”, or ICBT. The question proposed is, are these services as good for patient outcomes as traditional in-person CBT? A literature review was performed using electronic medical database PubMed with key word searches for cognitive behavior …
Effectiveness Of Knee Joint Injury Treatments In The Prevention Of Post-Traumatic Osteoarthritis, Jenna Zaeske
Effectiveness Of Knee Joint Injury Treatments In The Prevention Of Post-Traumatic Osteoarthritis, Jenna Zaeske
Physician Assistant Scholarly Project Papers
The purpose of this research and systematic literature review is to determine the effectiveness of rest, physical therapy, and/or surgical intervention following either anterior cruciate ligament (ACL) or meniscus injuries in short- and long- term osteoarthritis outcomes. The short- and longterm outcomes were evaluated to compare the prevalence and progression of osteoarthritis after joint injury. In this literature review, the electronic database PubMed was used to find relevant research. Many keywords were used when searching for articles. Sources included for review had research on ACL or meniscus injuries specifically. Other knee injuries, non-knee injuries and non-human subjects were excluded. Articles …
Gabapentin As An Effective Treatment Option For Alcohol Use Disorder, Monica Hurst
Gabapentin As An Effective Treatment Option For Alcohol Use Disorder, Monica Hurst
Physician Assistant Scholarly Project Papers
The purpose of this literature review is to determine whether gabapentin is an effective treatment option for alcohol use disorder (AUD). Utilizing data sourced primarily from published clinical trials, gabapentin’s effect on heavy drinking, abstinence, withdrawal symptoms and alcohol cravings will be explored. This review will also compare gabapentin’s efficacy against currently approved AUD treatment options, along with what dosages are most efficacious while contributing the fewest adverse effects. The data presented in this literature review undeniably demonstrates a positive effect of gabapentin on alcohol use disorder; Specifically, the data shows that gabapentin at multiple dosages helps to decrease heavy …
A Comparison Of Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies And Standard Migraine Prophylaxis In Those With Episodic Migraines, Alexie Harms
Physician Assistant Scholarly Project Papers
The purpose of this research study is to determine if anti-calcitonin gene related peptide monoclonal antibodies (CGRP mAbs) more effective and tolerable in reducing the number of migraine days in comparison to conventional migraine prophylactic use of Propranolol, Amitriptyline, and Topiramate. Migraines are debilitating and a frequent reason for primary care visits interfering with an individual’s work, school, and daily life. Standard of care treatment options for migraine prophylaxis are drugs initially developed for other diseases and can lead to unnecessary and unwanted side effects decreasing treatment adherence in the prevention of migraines. In this literature review, electronic search databases …
Fertility Treatment In Pcos: Metformin Vs. Inositol, Kaylina Kelley
Fertility Treatment In Pcos: Metformin Vs. Inositol, Kaylina Kelley
Physician Assistant Scholarly Project Papers
The most common endocrine disorder affecting women is polycystic ovary syndrome (PCOS) (Pourghasem, 2019). Metformin is commonly used to decrease insulin resistance and increase fertility in these women. However, it is known to cause many side effects, which are mostly gastrointestinal related. Myoinositol is a B-vitamin that is thought to also decrease insulin resistance and increase fertility with few side effects. The purpose of this literature review is to determine whether myoinositol is a comparable substitute for metformin in patients with PCOS suffering with infertility. This was done by evaluating pregnancy rates, insulin resistance, and side effects of metformin and …
Corticosteriod Injection Vs Therapy Vs Combination For Shoulder Rotator Cuff Injuries, Rodney Guy Palmer Jr.
Corticosteriod Injection Vs Therapy Vs Combination For Shoulder Rotator Cuff Injuries, Rodney Guy Palmer Jr.
Physician Assistant Scholarly Project Papers
Rotator cuff pathologies seen in a primary care setting ranks third for musculoskeletal complaints seen by primary care providers. Rotator cuff pathologies can cause significant dysfunction in activities of daily living (ADLs), work tasks, and daily life. Current treatment recommendations are intra-articular steroid injections, therapy only rehabilitation, or the combination of the two. This literature review researched articles comparing the effectiveness of steroid only treatments, therapy only treatments, and the combination of the two. There was conflicting evidence regarding which treatment was the most effective. Significant side effects for steroid injections were discovered which included rotator cuff rupture. Therapy demonstrated …
Platelet-Rich Plasma Vs Corticosteroid: Osteoarthritis Symptoms, Joshua Zetocha
Platelet-Rich Plasma Vs Corticosteroid: Osteoarthritis Symptoms, Joshua Zetocha
Physician Assistant Scholarly Project Papers
Osteoarthritis (OA) is a disease that hundreds of millions of people suffer from across the world (Palazzo et al., 2016). Currently, corticosteroid intra-articular injections are frequently administered to help with pain and inflammation related to OA (Pereira et al, 2015). A relatively new treatment option is Platelet-Rich Plasma (PRP) intra-articular injections. PRP injections use the patient’s own plasma, injected into the affected joint space, to reduce inflammation and potentially improve both pain and functionality. This literature review will investigate whether the newer PRP injections relieve pain and improve functionality of OA patients better than corticosteroid injections. The literature review was …
Pregnancy Planning: Hormonal Contraception Versus Natural Family Planning, Melanie Loehrer
Pregnancy Planning: Hormonal Contraception Versus Natural Family Planning, Melanie Loehrer
Physician Assistant Scholarly Project Papers
Statement of the problem: Natural family planning methods provide women with an opportunity to use natural methods to plan pregnancy. This is done through daily monitoring of symptoms and biomarker fluctuation in accordance with hormonal changes throughout the menstrual cycle to identify the fertile window. Through the identification of the fertile window and ovulation, one can determine appropriate days for sexual intercourse. This format allows participants to develop a greater understanding and in-depth knowledge of reproductive health to avoid or achieve pregnancy. The use of natural family planning has greatly increased over the last two decades, growing the demand for …
Perimenopausal Depression Screening And Treatment Efficacy Between Antidepressants And/Or Hormone Replacement Therapy, Mandy Stenehjem
Perimenopausal Depression Screening And Treatment Efficacy Between Antidepressants And/Or Hormone Replacement Therapy, Mandy Stenehjem
Physician Assistant Scholarly Project Papers
During the menopause transition (MT), also known as perimenopause, women are at a significantly increased risk of depression. Although the pathophysiology is not fully understood, it is likely to be complex and multifactorial. Data evaluating the involvement of HPA axis dysregulation and correlating female reproductive hormone fluctuations, specifically estradiol, are factors that may contribute to this incidence. Currently antidepressants are the treatment for depression but with biological changes occurring during perimenopause, hormone replacement therapy alone or in combination may have comparable antidepressant effects. The combination of menopause symptoms, depressive symptoms, and psychosocial challenges, make recognition and treatment depend on many …
Chronic Exertional Compartment Syndrome: Surgical Treatment Vs Conservative Care, Molly Ruebke
Chronic Exertional Compartment Syndrome: Surgical Treatment Vs Conservative Care, Molly Ruebke
Physician Assistant Scholarly Project Papers
Chronic exertional compartment syndrome (CECS) is a relatively rare pathology characterized by pain, tightness, and/or numbness in the affected calf upon performance of repetitive physical activity, most commonly with running or serving in the military. CECS usually has a delay in diagnosis due to low levels of awareness among clinicians and a wide range of differential diagnoses for chronic exertional leg pain. The natural course of CECS is often not self-limiting and therefore requires intervention, as symptoms can be severely debilitating and eventually force patients to avoid any provoking activity. The purpose of this literature review is to take a …
Benzimidazole Adjuvant Therapy: A Review Of Efficacy And Safety In Patients With Cancer, Jared Mouw
Benzimidazole Adjuvant Therapy: A Review Of Efficacy And Safety In Patients With Cancer, Jared Mouw
Physician Assistant Scholarly Project Papers
This literature review aims to compile previous studies’ data and explore the effects of benzimidazoles as an adjuvant therapy and its relationship to a patient’s cancer biomarkers, tumor progression, and quality of life. In addition to the aforementioned, we will attempt to review data to identify the safety and toxicity profile of benzimidazoles within a population of patients currently diagnosed with cancer to determine if this class of medications could be implemented along with current cancer treatment regimens to increase efficacy and tolerance. To determine this, the databases of CINAHL, ClinicalKey, and PubMed were searched with the keywords mentioned below. …
The Effects Of Food On Mood: Implications Of Mediterranean And Plant-Based Diets On Depression Symptom Prevalence And Severity, Kaitlyn Prochnow
The Effects Of Food On Mood: Implications Of Mediterranean And Plant-Based Diets On Depression Symptom Prevalence And Severity, Kaitlyn Prochnow
Physician Assistant Scholarly Project Papers
The purpose of this research and systematic literature review is to determine whether adherence to a Mediterranean diet or a plant-based diet has better effects on decreasing depression prevalence and/or symptom severity. A variety of keywords were used to search the online database, PubMed. Clinical trials and randomized controlled trials conducted within the last 20 years were included in the initial search. Exclusions were made if studies were not specific to Mediterranean or plant-based diets, or if they were focused on other psychiatric illnesses besides depression. For the final review, ten articles were selected. After thorough analyses and comparisons of …
Long-Term Control Of Type Ii Diabetes Mellitus And Weight Through Roux-En-Y Gastric Bypass Surgery Versus Weight Loss Medication, Alexandra Laber
Long-Term Control Of Type Ii Diabetes Mellitus And Weight Through Roux-En-Y Gastric Bypass Surgery Versus Weight Loss Medication, Alexandra Laber
Physician Assistant Scholarly Project Papers
Type II diabetes mellitus (T2DM) affects hundreds of millions of individuals in the United States and is only becoming more common. The disease can damage organs all throughout the body and even lead to death. The goal of treatment is to lower blood glucose, but since T2DM tends to be associated with obesity, another common goal in treatment is weight loss. However, this is difficult for many people to achieve, and intense medical treatment is sometimes needed. Since T2DM is a lifelong disease, interventions must be considered in the long term. The purpose of this project is to compare long-term …
Food Intolerance In Patients With Depression, Victoria Gingrey
Food Intolerance In Patients With Depression, Victoria Gingrey
Physician Assistant Scholarly Project Papers
Depression is a multifactorial condition affecting people worldwide. Medication is commonly prescribed for the treatment of depression, but some patients have difficulty finding a medication that is both effective and tolerable while others prefer to avoid medications all together. It has been suggested that dietary modification may reduce the depressive symptoms. As lifestyle changes may be difficult to maintain long term, determining specific foods to avoid for individual patients may improve adherence. A meta-analysis of 10 articles was performed. Articles were found using the electronic search databases PubMed and PsychInfo. Serology differences were appreciated between patients with depression and healthy …
The Effect Of Metformin Vs Lifestyle Modifications On The Prevention Of Prediabetes Progressing To Type Ii Diabetes, Brittany Mcpherson
The Effect Of Metformin Vs Lifestyle Modifications On The Prevention Of Prediabetes Progressing To Type Ii Diabetes, Brittany Mcpherson
Physician Assistant Scholarly Project Papers
Prediabetes is a common disease among American adults that is the predecessor to type 2 diabetes (T2D). T2D is a serious disease that causes long term damage to the heart, blood vessels, and kidneys if uncontrolled. This literature review looks at the effectiveness of medication (metformin), diet alone, exercise alone, and diet and exercise in combination in preventing the progression from prediabetes to a diagnosis of T2D. The literature review was performed using an electronic search database to identify literature related to preventing the conversion of prediabetes to T2D using either lifestyle modifications or metformin within the past five years. …
Benzimidazole Adjuvant Therapy: A Review Of Efficacy And Safety In Patients With Cancer, Jared Mouw
Benzimidazole Adjuvant Therapy: A Review Of Efficacy And Safety In Patients With Cancer, Jared Mouw
Physician Assistant Scholarly Project Posters
• The safety and toxicity profile of benzimidazoles will be assessed within a population of patients currently diagnosed with various types of cancer to determine if this class of medications could be implemented along with current cancer treatment regimens to increase efficacy and tolerance. • Databases of CINAHL, ClinicalKey, and PubMed were searched with the keywords mentioned below. Studies include those after the year 2000, and those focusing on the use of benzimidazoles on human cancer cells and tissue, case studies, or all phases of clinical trials. Excluded were those using non-human study subjects, those before the year 2000, and …
A Comparison Of Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies And Standard Migraine Prophylaxis In Those With Episodic Migraines, Alexie Harms
Physician Assistant Scholarly Project Posters
Migraines are debilitating and a frequent reason for primary care visits. Migraines interfere with an individual’s work, school, and daily life. Standard of care treatment options for migraine prophylaxis include Propranolol, Amitriptyline, and Topiramate which were all developed for other medical conditions. These conventional medications can lead to unwanted side effects decreasing treatment adherence. Calcitonin Gene-Related Peptide monoclonal antibodies (CGRP mAbs) have been under study for the treatment and prevention of migraines. The purpose of this research project is to explore the effectiveness and tolerability of CGRP mAbs in reducing the number of migraine days in comparison to conventional migraine …
Corticosteroid Injection Vs Therapy Vs Combination For Rotator Cuff Injuries, Rodney Guy Palmer Jr.
Corticosteroid Injection Vs Therapy Vs Combination For Rotator Cuff Injuries, Rodney Guy Palmer Jr.
Physician Assistant Scholarly Project Posters
Rotator cuff pathologies seen in a primary care setting ranks third for musculoskeletal complaints seen by primary care providers. Rotator cuff pathologies can cause significant dysfunction in activities of daily living (ADLs), work tasks, and daily life. Some current treatment recommendations are intra-articular steroid injections, therapy only rehabilitation, or the combination of the two. This literature review researched articles comparing the effectiveness of steroid only treatments, therapy only and the combination of the two. There was conflicting evidence regarding which treatment was the most effective. Significant side effects for steroid injections were discovered which included rotator cuff rupture. Therapy demonstrated …
Alternative Treatment Modalities For Plantar Fasciitis, Chelsey Clark
Alternative Treatment Modalities For Plantar Fasciitis, Chelsey Clark
Physician Assistant Scholarly Project Posters
Introduction: Plantar Fasciitis is a common condition in adult patients. The purpose of this literature review is to determine if there is any evidence for alternative treatments in the regimen of plantar fasciitis that has not been resolved with the standard treatment. Methods: The review was done using Pubmed, CINAHL and SportDiscus. Research was included on the following alternative treatments of PF: corticosteroid(CS) injections, extracorporeal shockwave(ESWT), dry needling, platelet-rich plasma (PRP), autologous blood injection (ABI), cupping, custom insoles, and ultrasound therapy (US). Twelve research articles are included. Results: The alternative treatments within this literature review had some promising statistically significant …
Effectiveness Of Knee Joint Injury Treatments In The Prevention Of Post-Traumatic Osteoarthritis, Jenna Zaeske
Effectiveness Of Knee Joint Injury Treatments In The Prevention Of Post-Traumatic Osteoarthritis, Jenna Zaeske
Physician Assistant Scholarly Project Posters
The purpose of this research and systematic literature review is to determine the effectiveness of conservative versus surgical intervention following anterior cruciate ligament (ACL) or meniscus injuries. Short and long term studies were evaluated to compare the prevalence and progression of osteoarthritis after joint injury. Sources included for review had research on ACL or meniscus injuries specifically. Other knee injuries, non-knee injuries and non-human subjects were excluded. After inclusion and exclusion criteria were implemented, 11 articles remained. Patients with ACL and meniscus injuries have a high prevalence of post-traumatic osteoarthritis (PTOA). Studies have shown that trialing physical therapy, specifically neuromuscular …
Roundtable: Issue 2, Mackenzie Amerman, Kalyn Bohrer, Eliza Schueneman, Victoria Voss
Roundtable: Issue 2, Mackenzie Amerman, Kalyn Bohrer, Eliza Schueneman, Victoria Voss
Roundtable: Journal of the UND Honors Program
No abstract provided.
Chronic Exertional Compartment Syndrome: Surgical Treatment Vs Conservative Care, Molly Ruebke
Chronic Exertional Compartment Syndrome: Surgical Treatment Vs Conservative Care, Molly Ruebke
Physician Assistant Scholarly Project Posters
• Summary of Problem: Chronic exertional compartment syndrome (CECS) is a relatively rare pathology characterized by pain, tightness, and/or numbness in the affected calf upon performance of repetitive physical activity, most commonly with running or serving in the military. CECS usually has a delay in diagnosis due to low levels of awareness among clinicians and a wide range of differential diagnoses for chronic exertional leg pain. The natural course of CECS is often not self-limiting and therefore requires intervention, as symptoms can be severely debilitating and eventually force patients to avoid any provoking activity. The purpose of this literature review …
Comparison Of Urethral Bulking Injection Therapy And Surgical Midurethral Sling Placement For Treatment Of Stress Urinary Incontinence In Women, Ashley Black
Physician Assistant Scholarly Project Posters
This literature review aims to assess the comparative efficacy and safety of urethral bulking injection therapy and surgical midurethral sling intervention in the treatment of stress incontinence in women. A comprehensive search of the existing literature was conducted and includes studies from PubMed, an electronic search databases. The findings indicate that both urethral bulking injection therapy and surgical midurethral sling intervention are suitable interventions to be considered for the treatment of stress incontinence in women. Current research available regarding the efficacy of urethral bulking agents versus midurethral slings suggests that the placement of a miduerthral sling has the highest incidence …
Weight Loss For Bariatric Patients: Arterial Embolization Versus Gastric Bypass, Morgan Bernhardt
Weight Loss For Bariatric Patients: Arterial Embolization Versus Gastric Bypass, Morgan Bernhardt
Physician Assistant Scholarly Project Posters
The primary aim of this review is to determine the safety and efficacy of left gastric artery embolization (LGAE) in comparison to Roux-en-Y gastric bypass (RYGB) in bariatric patients for the treatment of obesity. RYGB, an invasive surgical operation, has been proven to result in long-term efficacy of weight loss but can be associated with a higher risk of early and long-term complications to include a gastrojejunal anastomosis leak, surgical site infection, iron deficiency anemia, bowel obstructions, and hernias. RYGB may require reoperation and does have a risk of mortality. Bariatric surgery is now focusing on the appetite-stimulating …