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Predictors Of Assertive And Nonassertive Styles Of Self-Defense Behavior During A Lab-Based Sexual Assault Scenario, Raeann E. Anderson, Shawn P. Cahill, Kristin E. Silver, Douglas D. Delahanty Feb 2019

Predictors Of Assertive And Nonassertive Styles Of Self-Defense Behavior During A Lab-Based Sexual Assault Scenario, Raeann E. Anderson, Shawn P. Cahill, Kristin E. Silver, Douglas D. Delahanty

Psychology Faculty Publications

The current study examined how psychological factors influence hypothetical behavioral responses to threat (BRTT). College women (n = 113) with a history of sexual victimization completed a standardized lab-based self-defense scenario. Interpersonal skills, coping style, and assertive and non-assertive BRTT during a prior assault predicted assertive BRTT during the task. The use of non-assertive BRTT during past assaults no longer predicted assertive BRTT during the task when accounting for rape acknowledgment. Findings regarding rape acknowledgment demonstrate the complexity of recovery from sexual assault. Our results highlight interpersonal skills as an intervention target for innovative sexual assault risk reduction interventions.


Monitoring Landscape Dynamics In Central U.S. Grasslands With Harmonized Landsat-8 And Sentinel-2 Time Series Data, Qiang Zhou, Jennifer Rover, Jesslyn Brown, Bruce Worstell, Danny Howard, Zhuoting Wu, Alisa L. Gallant, Bradley Rundquist, Morgen Walter Victor Burke Feb 2019

Monitoring Landscape Dynamics In Central U.S. Grasslands With Harmonized Landsat-8 And Sentinel-2 Time Series Data, Qiang Zhou, Jennifer Rover, Jesslyn Brown, Bruce Worstell, Danny Howard, Zhuoting Wu, Alisa L. Gallant, Bradley Rundquist, Morgen Walter Victor Burke

Geography & Geographic Information Science Faculty Publications

Remotely monitoring changes in central U.S. grasslands is challenging because these landscapes tend to respond quickly to disturbances and changes in weather. Such dynamic responses influence nutrient cycling, greenhouse gas contributions, habitat availability for wildlife, and other ecosystem processes and services. Traditionally, coarse-resolution satellite data acquired at daily intervals have been used for monitoring. Recently, the harmonized Landsat-8 and Sentinel-2 (HLS) data increased the temporal frequency of the data. Here we investigated if the increased data frequency provided adequate observations to characterize highly dynamic grassland processes. We evaluated HLS data available for 2016 to (1) determine if data from Sentinel-2 …


Parp-1/2 Inhibitor Olaparib Prevents Or Partially Reverts Emt Induced By Tgf-Β In Nmumg Cells, Michelle Schacke, Janani Kumar, Nicholas Colwell, Kole Hermanson, Gustavo A. Folle, Sergei Nechaev, Archana Dhasarathy, Laura Lafon-Hughes Jan 2019

Parp-1/2 Inhibitor Olaparib Prevents Or Partially Reverts Emt Induced By Tgf-Β In Nmumg Cells, Michelle Schacke, Janani Kumar, Nicholas Colwell, Kole Hermanson, Gustavo A. Folle, Sergei Nechaev, Archana Dhasarathy, Laura Lafon-Hughes

Biomedical Sciences Faculty Publications

Poly- adenosine diphosphate (ADP)-ribose (PAR) is a polymer synthesized as a posttranslational modification by some poly (ADP-ribose) polymerases (PARPs), namely PARP-1, PARP-2, tankyrase-1, and tankyrase-2 (TNKS-1/2). PARP-1 is nuclear and has also been detected in extracellular vesicles. PARP-2 and TNKS-1/2 are distributed in nuclei and cytoplasm. PARP or PAR alterations have been described in tumors, and in particular by influencing the EpithelialMesenchymal Transition (EMT), which influences cell migration and drug resistance in cancer cells. Pro-EMT and anti-EMT effects of PARP-1 have been reported while whether PAR changes occur specifically during EMT is currently unknown. The PARP-1/2 inhibitor Olaparib (OLA) is …


Investigating Graduate Education And Undergraduate Research Intentions Of College Science Students, Eric D. Deemer, Rachel L. Navarro, Angela M. Byars-Winston, Laura E. Jensen, Catherine P. Chen Jan 2019

Investigating Graduate Education And Undergraduate Research Intentions Of College Science Students, Eric D. Deemer, Rachel L. Navarro, Angela M. Byars-Winston, Laura E. Jensen, Catherine P. Chen

Education, Health & Behavior Studies Faculty Publications

The current study examined predictors of undergraduate science students’ intentions to attend graduate school and participate in undergraduate research. We used social cognitive career theory to test our hypothesized model using a sample (N ¼ 411) of life science and physical science majors and examined basic interests in these disciplines as mediating variables. Among life science majors, results of structural equation modeling indicated that microbiology interest mediated the relationship between scientific self-efficacy (SSE) and graduate education intentions (GEIs) and the latter variable also mediated the relationship between microbiology interest and undergraduate research intentions (URIs). The model for physical science majors …


Volume 56, Number 20: January 02, 2019, University Of North Dakota Jan 2019

Volume 56, Number 20: January 02, 2019, University Of North Dakota

University Letter Archive

No abstract provided.


A Comparison Of Two In-Class Anxiety Reduction Exercises Before A Final Exam, Virginia Clinton, Stacy Meester Jan 2019

A Comparison Of Two In-Class Anxiety Reduction Exercises Before A Final Exam, Virginia Clinton, Stacy Meester

Educational Foundations and Research Faculty Publications

The purpose of this quasi-experiment is to test two different methods for helping students reduce anxiety before an exam. Students in two introductory psychology courses (N = 111) engaged in either a focused-breathing or expressive-writing exercise before their final exam. Results indicated that, compared to previous exam performance, both focused breathing and expressive writing improved performance for students with high levels of trait test anxiety. However, there was no effect on final exam performance for either method for students with low levels of trait test anxiety. Both exercises appeared to reduce state anxiety for students, although the reduction was greater …


Ca2+ Entry Via Trpc1 Is Essential For Cellular Differentiation And Modulates Secretion Via The Snare Complex, Thad A. Rosenberger, Anne Schaar, Yuygang Sun, Pramod Sukumaran, Danielle Krout, James N. Roemmich, Lutz Brinbaumer, Kate Claycombe-Larson, Brij B. Singh Jan 2019

Ca2+ Entry Via Trpc1 Is Essential For Cellular Differentiation And Modulates Secretion Via The Snare Complex, Thad A. Rosenberger, Anne Schaar, Yuygang Sun, Pramod Sukumaran, Danielle Krout, James N. Roemmich, Lutz Brinbaumer, Kate Claycombe-Larson, Brij B. Singh

Biomedical Sciences Faculty Publications

Adipocyte functionality, including adipocyte differentiation and adipokine secretion, is essential in obesity-associated metabolic syndrome. Here, we provide evidence that Ca2+ influx in primary adipocytes, especially upon store-depletion, plays an important role in adipocyte differentiation, functionality, and subsequently metabolic regulation. The endogenous Ca2+ entry channel in both subcutaneous and visceral adipocytes was dependent on TRPC1-STIM1 and blocking Ca2+ entry with SKF-96365 or TRPC1-/- derived adipocytes inhibited adipocyte differentiation. Additionally, TRPC1-/- mice have decreased organ weight, but increased adipose deposition and reduced serum adiponectin and leptin concentrations, without affecting total adipokine expression. Mechanistically, TRPC1- mediated Ca2+ entry regulated SNARE complex formation and …


The Impact Of Shift Work On Health And Wellbeing, Stephanie Gagelin Jan 2019

The Impact Of Shift Work On Health And Wellbeing, Stephanie Gagelin

Physician Assistant Scholarly Project Posters

Many of today’s industries require workers to perform shift work (typically during 1600-0700). If workers are awake during this time period, circadian misalignment occurs. This scholarly project uses research studies and metaanalyses to provide information about increased health risks associated with circadian misalignment, focusing on the categories of glucose metabolism, cardiovascular system, carcinogenesis, and mental health and acuity.

• Shift work has been found to increase BMI and waist circumference of employees, as well as increase blood glucose levels to “prediabetic” levels in previously euglycemic individuals.

• Shift work has been proven to increase high-sensitivity C-reactive protein (hs-CRP), an acute …


Platelets To The Rescue? A Literature Review Of The Safety And Efficacy Of Platelet Rich Plasma For Symptomatic Osteoarthritis Of The Knee, Timothy Simonich Jan 2019

Platelets To The Rescue? A Literature Review Of The Safety And Efficacy Of Platelet Rich Plasma For Symptomatic Osteoarthritis Of The Knee, Timothy Simonich

Physician Assistant Scholarly Project Posters

Osteoarthritis of the knee is one of the most common joint disorders in the United States with rising prevalence due to obesity and an aging population. Regarding non surgical approaches to management, there has been growing interest in the use of intra articular injections with Platelet Rich Plasma (PRP).


Evolution Of Occupational Therapy Practice: Life History Of Joan Rogers, Phd, Otr/L, Faota, Michelle Arnhalt, Ivy Steiger Jan 2019

Evolution Of Occupational Therapy Practice: Life History Of Joan Rogers, Phd, Otr/L, Faota, Michelle Arnhalt, Ivy Steiger

Oral History Posters

Objective: This qualitative study was to examine the evolution of occupational therapy practice throughout the life history and career of Joan Rogers. The purpose of the study is to provide current and future generations of occupational therapists a view of the history and how occupational therapy practice has evolved from its inception to current practice through the life history stories of occupational therapists who have held leadership roles at the national level and beyond.

Method: The Kawa Model guided Semi-structured interview questions. Throughout the interview process, the researchers gained information regarding Joan Roger’s experiences related to gaining her occupational therapy …


Aspirin Use Following Preeclampsia To Prevent Future Adverse Cardiovascular Outcomes, Kristi Bohlig Jan 2019

Aspirin Use Following Preeclampsia To Prevent Future Adverse Cardiovascular Outcomes, Kristi Bohlig

Physician Assistant Scholarly Project Posters

• Introduction: Preeclampsia during pregnancy warrants therapy with low dose aspirin. The purpose of this review is to investigate if these women are at increased future risk for cardiovascular morbidity and mortality, and if aspirin therapy prevents future cardiovascular events.

• Research Questions: Do women who had preeclampsia during pregnancy have increased future cardiovascular morbidity and mortality? • Does continued aspirin use in postpartum women, who had preeclampsia during pregnancy; decrease future cardiovascular morbidity and mortality?

• Research Methods: Literature review was conducted utilizing CINAHL, Dynamed plus and PubMed databases.

• Discussion: Many studies have found that preeclampsia does increase …


Outpatient Pt Management Of Patient With Bilateral Knee Pain S/P Stem Cell Cartilage Replacement Therapy Of Both Knees, Justin Hett Jan 2019

Outpatient Pt Management Of Patient With Bilateral Knee Pain S/P Stem Cell Cartilage Replacement Therapy Of Both Knees, Justin Hett

Physical Therapy Scholarly Projects

Background and Purpose: This article describes the 6-week outpatient physical therapy management of a 65-year-old male who c/o bilateral knee pain s/p stem cell cartilage replacement therapy. The patient presented with decreased ROM in both knees R>L, difficulty ambulating moderate distances, knee pain, and decreased LE strength bilaterally. The purpose of this article is to describe the treatments used for this patient and the results from these treatments.

Description: The treatment of this patient involved range of motion, strengthening, patient education, and stretching.

Outcomes: Following PT intervention, the patient had increased ROM in both knees L>R, normal strength, …


Standard And Cognitive Four Square Step Test (Fsst), Renee Hoffman, Hannah Bucholz Jan 2019

Standard And Cognitive Four Square Step Test (Fsst), Renee Hoffman, Hannah Bucholz

Physical Therapy Scholarly Projects

Background/Purpose: The Four Square Step Test (FSST) measures dynamic standing balance and agility and was developed to identify older adults at risk for falls. It has a cognitive component for remembering the stepping sequence but has never been tested with an additional cognitive task. The purpose of this study was to collect normative data for the FSST and Cognitive FSST in community dwelling adults for various age groups.

Materials/Methods: Eighty-seven community-dwelling adults (55 females, 32 males) between the age 21 and 86 (48.22 years) were included in the study. Participants completed a fall risk checklist and a cognitive screen prior …


Pelvic Examinations For Ovarian Cancer Screening In Asymptomatic Adult Women, Riann Collar Jan 2019

Pelvic Examinations For Ovarian Cancer Screening In Asymptomatic Adult Women, Riann Collar

Physician Assistant Scholarly Project Posters

There is discrepancy amongst organizations and the medical community whether bimanual pelvic examinations should be performed in asymptomatic women for routine screening. The purpose of this literature review was to determine whether bimanual pelvic examinations are beneficial for screening for ovarian cancer in comparison to no screening. In addition, research was conducted to see if healthcare providers’ professional beliefs align with the evidence and national recommendations, to determine women’s thoughts and beliefs regarding pelvic examinations, and identify other screening methods if bimanual pelvic exams are determined to be an invalid screening tool. Throughout reviewing peer reviewed articles and high-quality evidence, …


Parenteral Ascorbic Acid For Treatment Of Sepsis, Lindsey Hiatt Jan 2019

Parenteral Ascorbic Acid For Treatment Of Sepsis, Lindsey Hiatt

Physician Assistant Scholarly Project Posters

Sepsis kills nearly 1 million people each year in the United States and sepsis-related hospitalizations cost approximately $24 billion annually (Paoli, Reynolds, Sinha, Gitlin, & Crouser, 2018). Current treatment guidelines are limited to targeted antibiotics and hemodynamic support. While antibiotics are the definitive treatment to eradicate the infectious pathogen, there are currently no standard-of-care treatments that consistently and successfully attenuate the damage sustained to the body by its own inflammatory response to infection. Many different treatments have been trialed and failed to show improved outcomes. Vitamin C, or ascorbic acid, has long been associated with supporting immune function, and has …


The Use Of Dhea In The Treatment Of Depression, Bryan Tipton Jan 2019

The Use Of Dhea In The Treatment Of Depression, Bryan Tipton

Physician Assistant Scholarly Project Posters

No abstract provided.


Obesity: Modern Medicine Vs. Lifestyle, Jenny Christianson Jan 2019

Obesity: Modern Medicine Vs. Lifestyle, Jenny Christianson

Physician Assistant Scholarly Project Posters

• Obesity is a rising epidemic, and is one of the most common, costly and preventable health problems the world is experiencing today (Center for Disease Control and Prevention, [CDC], 2017).

• From this, it is important to establish an effective treatment plan that can be implemented across the nation for maximum patient benefit.

• Lifestyle changes such as diet and exercise are important to any health care plan and are equally necessary to reduce health risks. However, in certain patients, lifestyle changes are not enough due to the maladaptive biologic process in their brain. Thus, additional treatment options need …


Evolution Of Occupational Therapy Practice: Life History Of Sandy Hanebrink, Otr/L, Clp, Faota, Amira Ragab Jan 2019

Evolution Of Occupational Therapy Practice: Life History Of Sandy Hanebrink, Otr/L, Clp, Faota, Amira Ragab

Oral History Student Papers

The purpose of the life history project is to examine Sandy Hanebrink’s occupational therapy practice and how the profession has evolved at the national level. By completing a literature review, gathering information on the participant, and completing a semi-structured video interview, the researcher was able to analyze the data. The findings from the data emerged into three categories: systematic evolution of the OT profession, personal journey, and influences over the years. The categories were then formed into two overall assertions: Over the years, the systematic evolution of occupational therapy, countless influences, and her personal journey to become an occupational therapist …


A Case Report: Factors Influencing The Physical Therapy Care Following Medical Treatment Of An Anaplastic Oligodendroglioma, Connor Camrud Jan 2019

A Case Report: Factors Influencing The Physical Therapy Care Following Medical Treatment Of An Anaplastic Oligodendroglioma, Connor Camrud

Physical Therapy Scholarly Projects

Purpose The purpose of this case report is to describe the clinical decision-making processes of the physical therapy (PT) care for a patient who was diagnosed with an anaplastic oligodendroglioma and subsequently had surgical decompression and resection, chemotherapy, and radiation.

Background Anaplastic oligodendrogliomas account for 3% to 20% of all brain tumors. The incidence of this tumor is 40% greater in males than females. Average onset occurs between 35 and 44 years of age. Anaplastic oligodendrogliomas commonly occur in the frontal lobes and are supratentorial. Patients will often present with headaches, new weakness, vision changes, and a decline in cognitive …


On The Interpretation Of The Normalization Constant In The Scaling Equation, Karl J. Niklas, Sean T. Hammond Jan 2019

On The Interpretation Of The Normalization Constant In The Scaling Equation, Karl J. Niklas, Sean T. Hammond

Earth System Science and Policy Faculty Publications

The scaling equation, Y1 = βYα2, has been used empirically and explored theoretically primarily to determine the numerical value and meaning of the scaling exponent, α. The mathematical interpretation of α is clear—it is the quotient of the relative rate of change of Y1 with respect to the rate of change of Y2. In contrast, the interpretation of the normalization constant, β, is obscure, so much so that some workers have rejected the idea that it has any biological importance. With the notable exception of Steven J. Gould's early work, Huxley's dismissal of β largely relegated the study of its …


Finding Common Rules Of Robustness And Resilience That Span Multiple Levels Of Biological Organization, Robert Burnap, Jing Chen, Erica Crespi, Moumita Das, Rebecca Simmons, Zhen Wang, Jie Xiao, Bing Yang, John Yin Jan 2019

Finding Common Rules Of Robustness And Resilience That Span Multiple Levels Of Biological Organization, Robert Burnap, Jing Chen, Erica Crespi, Moumita Das, Rebecca Simmons, Zhen Wang, Jie Xiao, Bing Yang, John Yin

Biology Faculty Publications

Today, humans as a species face significant global challenges: meeting the needs of an ever expanding human population for food and energy from limited land, water and other resources; finding ways to counter rapidly changing pathogens that become resistant to current treatments; adapting to climate change that is linked to more frequent flooding, drought, wildfires and temperature extremes; and reversing the deterioration of ecosystems associated with human induced alterations of the environment. Owing to its resilience and robustness, life in one form or another will likely persist, but it is unknown by what mechanisms or in what forms. Much is …


Integrated Microfluidic Systems With Sample Preparation And Nucleic Acid Amplification, Juxin Yin, Yuanjie Suo, Zheyu Zou, Jingjing Sun, Shan Zheng, Ben Wang, Yawei Xu, Diane C. Darland, Julia Zhao, Ying Mu Jan 2019

Integrated Microfluidic Systems With Sample Preparation And Nucleic Acid Amplification, Juxin Yin, Yuanjie Suo, Zheyu Zou, Jingjing Sun, Shan Zheng, Ben Wang, Yawei Xu, Diane C. Darland, Julia Zhao, Ying Mu

Biology Faculty Publications

Rapid, efficient and accurate nucleic acid molecule detection is important in the screening of diseases and pathogens, yet remains a limiting factor at point of care (POC) treatment. Microfluidic systems are characterized by fast, integrated, miniaturized features which provide an effective platform for qualitative and quantitative detection of nucleic acid molecules. The nucleic acid detection process mainly includes sample preparation and target molecule amplification. Given the advancements in theoretical research and technological innovations to date, nucleic acid extraction and amplification integrated with microfluidic systems has advanced rapidly. The primary goal of this review is to outline current approaches used for …


Integrated Management Of Invasive Cattails (Typha Spp.) For Wetland Habitat And Biofuel In The Northern Great Plains Of The United States And Canada: A Review, Dan Svedarsky, Richard Grosshans, Henry David Venema, Susan N. Ellis-Felege, J. Bruggman, Aaron Ostlund, Jeff Lewis Jan 2019

Integrated Management Of Invasive Cattails (Typha Spp.) For Wetland Habitat And Biofuel In The Northern Great Plains Of The United States And Canada: A Review, Dan Svedarsky, Richard Grosshans, Henry David Venema, Susan N. Ellis-Felege, J. Bruggman, Aaron Ostlund, Jeff Lewis

Biology Faculty Publications

On many public lands in the Great Plains region of the USA and Canada, cattail (Typha spp.) growth has far exceeded the 50:50 distribution recommended for optimum wetland wildlife habitat. Excessive cattail growth is the primary concern of wetland managers and its integrated management is reviewed here. The coverage of this mostly hybrid cattail (T. latifolia × T. angustifolia) is often over 90 % and if partially removed for habitat enhancement represents a substantial biomass resource in sites such as conservation wetlands, water retention basins and roadside drainage ditches. Available biomass is estimated to be 3,000 kg/ha assuming a 50 …


The 20-M Shuttle Run: Assessment And Interpretation Of Data In Relation To Youth Aerobic Fitness And Health, Grant R. Tomkinson, Justin J. Lang, Joel Blanchard, Luc A. Léger, Mark S. Tremblay Jan 2019

The 20-M Shuttle Run: Assessment And Interpretation Of Data In Relation To Youth Aerobic Fitness And Health, Grant R. Tomkinson, Justin J. Lang, Joel Blanchard, Luc A. Léger, Mark S. Tremblay

Education, Health & Behavior Studies Faculty Publications

Cardiorespiratory fitness (CRF) is a good summative measure of the body’s ability to perform continuous, rhythmic, dynamic, large-muscle group physical activity, and exercise. In children, CRF is meaningfully associated with health, independent of physical activity levels, and it is an important determinant of sports and athletic performance. Although gas-analyzed peak oxygen uptake is the criterion physiological measure of children’s CRF, it is not practical for population-based testing. Field testing offers a simple, cheap, practical alternative to gas analysis. The 20-m shuttle run test (20mSRT)—a progressive aerobic exercise test involving continuous running between 2 lines 20 m apart in time to …


The Effects Of An Early Motion Protocol For Rehabilitation Following A Massive Rotator Cuff Tear Repair: A Case Report, Kody Strum Jan 2019

The Effects Of An Early Motion Protocol For Rehabilitation Following A Massive Rotator Cuff Tear Repair: A Case Report, Kody Strum

Physical Therapy Scholarly Projects

Background and Purpose: Rotator cuff tears are one of the most common musculoskeletal injuries to occur in the United States. Following a surgical repair, there are two main rehabilitation protocols: early motion and delayed motion. Despite the large number of patients in need of rehab following a rotator cuff tear surgical repair, there is not yet a definitive answer in the literature as far as the best protocol to use.

Case Description: The patient was a 68-year-old male who injured himself while slipping and attempting to catch himself with his right arm. He presented to physical therapy following a surgical …


Using The Landing Error Scoring System (Less) To Predict The Risk Of Lower Extremity Injuries In Athletes, Marit Mikkelsen, Anthony Peterson, Travis Rinkenberger Jan 2019

Using The Landing Error Scoring System (Less) To Predict The Risk Of Lower Extremity Injuries In Athletes, Marit Mikkelsen, Anthony Peterson, Travis Rinkenberger

Physical Therapy Scholarly Projects

Introduction: Athletes that participate in any sport are at an increased risk of injury, especially lower extremity injury. In particular, many athletes experience anterior cruciate ligament (ACL) injury during competition and practice sessions. The Landing Error Scoring System (LESS) is a tool used to identify athletes with a higher potential risk for ACL injury.

Purpose: The purpose of this study is to compare vertical jump landing mechanics between genders and among various sports.

Methods: Forty-one participants (21 females, 20 males) were recruited from a NCAA Division I university. Participants were from the following sports: football, volleyball, women’s soccer, and men’s …


Test-Retest Reliability Of Trimp In Collegiate Ice Hockey Players, Jason G. Ulmer, Grant R. Tomkinson, Sandra E. Short, Martin Short, John S. Fitzgerald Jan 2019

Test-Retest Reliability Of Trimp In Collegiate Ice Hockey Players, Jason G. Ulmer, Grant R. Tomkinson, Sandra E. Short, Martin Short, John S. Fitzgerald

Education, Health & Behavior Studies Faculty Publications

The utility of the heart rate derived variable TRaining IMPulse (TRIMP) for assessing internal training load in ice hockey players is not clear. Having a reliable measure of internal training load during on-ice training sessions would help coaches program exercise training. This study determined the reliability of TRIMP during on-ice training sessions in ice hockey players. Twelve Division I collegiate male ice hockey players (aged 18–23 years) had their heart rate (HR) data recorded during two on-ice practice sessions separated by two weeks. TRIMP and other descriptive HR variables were compared between sessions. TRIMP demonstrated moderate reliability during on-ice sessions. …


Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman Jan 2019

Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman

Oral History Posters

With the high incidence of Lyme disease in the endemic areas of North America, it is important to appropriately diagnosis and treat this condition to prevent post treatment Lyme disease syndrome (PTLDS).

Background information regarding Lyme disease is given. The purpose of this research is to discuss the treatment options available for those patients that fit the case definition of PTLDS. A literature review was conducted using several different electronic databases finding peer reviewed research articles pertaining to the treatment options available for PTLDS. Extended antibiotic use is shown to be not beneficial in most cases. Alternative treatment options listed …


The Use Of Dehydroepiandrosterone For Treatment Of Depression, Bryan Tipton Jan 2019

The Use Of Dehydroepiandrosterone For Treatment Of Depression, Bryan Tipton

Physician Assistant Scholarly Project Papers

Dehydroepiandrosterone (DHEA) and its sulfated ester (DHEA-S) are important pre-hormones that also have direct neurohormonal effects on the central nervous system. Over the last twenty years, data have revealed that serum DHEA peaks in a person’s mid-20s and steadily declines throughout their lifetime. In addition, women tend to have lower values than men. This is of note because lower serum values tend to be correlated with increased risk of depression, worse depressive symptoms, and increased risk of relapse into depression. A review of literature concerning DHEA’s age related values, its association with depression, and its use in the treatment of …


Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman Jan 2019

Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman

Physician Assistant Scholarly Project Posters

With the high incidence of Lyme disease in the endemic areas of North America, it is important to appropriately diagnosis and treat this condition to prevent post treatment Lyme disease syndrome (PTLDS). Background information regarding Lyme disease is given. The purpose of this research is to discuss the treatment options available for those patients that fit the case definition of PTLDS. A literature review was conducted using several different electronic databases finding peer reviewed research articles pertaining to the treatment options available for PTLDS. Extended antibiotic use is shown to be not beneficial in most cases. Alternative treatment options listed …