Digital Commons Network^™

Maximizing Mental Health With Early Detection In The Outpatient Setting: Provider Education On Suicide Screening, Elizabeth A. Doddato

Nursing Capstones

Background: Despite advancements in research, increased efforts to identify “best practices” for suicide prevention, and the subsequent development of evidence-based interventions, suicide trends continue to rise at epidemic proportions. Objective: The project’s purpose is to highlight the significance and benefit of utilizing and implementing evidence-based research interventions into the primary investigator’s outpatient psychiatric organization. Goal: The project’s goal is to determine if provider-specific education on suicide screening enhanced the provider’s comfort level, knowledge-base, and otherwise positively impacted their plan for future implementation of such tools that would ultimately assist in the early detection of at-risk patients. Methods: The project used …

Improving Palliative Care Utilization Process: An Effort To Enhance Providers` Contribution, Orina Machoka

Nursing Capstones

Worldwide, an estimated 20 million people require palliative care. The Worldwide Palliative Care Alliance has identified the need for palliative care has never been higher and is increasing at a rapid rate due to the world`s aging population, increase in cancer, and noncommunicable disease. Despite the increased need, the palliative care establishment has not been efficient in identifying patients who need palliative care. The use of a standardized screening process to assist in the timely identification of patients with palliative care needs is lacking, or in some cases, non-existent. At a Midwestern pain clinic lack of screening is causing a …

Primary Care And Behavioral Health Provider Communication: Strategy For Improvement, Kathleen J. Matthews

Nursing Capstones

Communication in health care is essential. Limited communication between primary care and behavioral health providers was identified as a barrier access to care and effective collaborative care of patients seeking behavioral health treatment in the Matanuska-Susitna (Mat-Su) Borough, Alaska. A one-group pre- and post-test design quality improvement project was created to develop and implement a standardized communication template to facilitate communication and collaboration between behavioral health and primary care providers in the project group. The theory of relational coordination with an emphasis on the mutually reinforcing interaction between relationships and communication served as the theoretical framework for the project. Objectives …

April 2, 2020: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the April 2, 2020, meeting of the University Senate. 14 pages

Criterion-Referenced Mcaft Cut-Points To Identify Metabolically Healthy Cardiorespiratory Fitness Among Adults Aged 18–69 Years: An Analysis Of The Canadian Health Measures Survey, Emily Wolfe Phillips, Deepa P. Rao, Leonard A. Kaminsky, Grant Tomkinson, Robert Ross, Justin J. Lang

Education, Health & Behavior Studies Faculty Publications

Objective: This study aimed to develop and validate health-related criterion-referenced cutpoints for the modified Canadian Aerobic Fitness Test (mCAFT), a field-based measure to predict cardiorespiratory fitness (CRF) among adults (18–69 years). Methods: Criterionreferenced mCAFT cut-points were developed using nationally representative data from cycles 1 (2007–09) and 2 (2009–11) of the Canadian Health Measures Survey (CHMS). Receiver operating characteristic curves were used to identify age- and sex-specific cut-points for measured waist circumference, blood pressure, and high-density lipoprotein. Cut-points were validated against metabolic syndrome using a fasted sub-sample (n=1,093) from cycle 5 (2016– 17). Results: 4,967 participants (50% women) were retained for …

Deep Multilayer Brain Proteomics Identifies Molecular Networks In Alzheimer's Disease Progression, Bing Bai, Xusheng Wang, Yuxin Li, Ping-Chung Chen, Kaiwen Yu, Kaushik Kumar Dey, Jay M. Yarbro, Xian Han, Brianna M. Lutz, Shuquan Rao, Yun Jiao, Jeffrey M. Sifford, Jonghee Han, Minghui Wang, Haiyan Tan, Timothy I. Shaw, Ji-Hoon Cho, Suiping Zhou, Hong Wang, Mingming Niu, Ariana Mancieri, Kaitlynn A. Messler, Xiaojun Sun, Zhiping Wu, Vishwajeeth Pagala, Anthony A. High, Wenjian Bi, Hui Zhang, Hongbo Chi, Vahram Haroutunian, Bin Zhang, Thomas G. Beach, Gang Yu, Junmin Peng

Biology Faculty Publications

Alzheimer's disease (AD) displays a long asymptomatic stage before dementia. We characterize AD stage-associated molecular networks by profiling 14,513 proteins and 34,173 phosphosites in the human brain with mass spectrometry, highlighting 173 protein changes in 17 pathways. The altered proteins are validated in two independent cohorts, showing partial RNA dependency. Comparisons of brain tissue and cerebrospinal fluid proteomes reveal biomarker candidates. Combining with 5xFAD mouse analysis, we determine 15 Aβ-correlated proteins (e.g., MDK, NTN1, SMOC1, SLIT2, and HTRA1). 5xFAD shows a proteomic signature similar to symptomatic AD but exhibits activation of autophagy and interferon response and lacks human-specific deleterious events, …

Sleeping Time Is Associated With Functional Limitations In A National Sample Of Older Americans, Brenda M. Vincent, Nathaniel Johnson, Grant R. Tomkinson, Ryan Mcgrath, Brian C. Clark, Bong-Jin Choi

Education, Health & Behavior Studies Faculty Publications

Background: Engaging in healthy behaviors may help to preserve function during aging; however, it is not well understood how sleeping time is associated with functional capacity in older adults.

Aims: We sought to determine the association of sleeping time on functional limitation in a national sample of older Americans.

Methods: The analytical sample included 6,020 adults aged at least 65 years who participated in the 2007-2016 waves of the National Health and Nutrition Examination Survey. Respondents indicated their hours of sleep/week night and were categorized as <5, 5-6.5, 7-8, 8.5-9, and >9 hours of sleep/week night. Ability to complete 19 functional tasks …

March 10, 2020, The Dakota Student

The Dakota Student

No abstract provided.

March 5, 2020, University Of North Dakota

University Senate Meeting Minutes

Minutes from the March 5, 2020, meeting of the University Senate. 4 pages

March 3, 2020, The Dakota Student

The Dakota Student

No abstract provided.

Discussion Of “Establishing Modified Canadian Aerobic Fitness Test (Mcaft) Cut-Points To Detect Clustered Cardiometabolic Risk Among Canadian Children And Youth Aged 9 To 17 Years” – The Need For Foundational Fitness Research In Canada: Is There Room For Innovation?, Mark S. Tremblay, Grant R. Tomkinson

Education, Health & Behavior Studies Faculty Publications

No abstract provided.

March 5, 2020: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the March 5, 2020, meeting of the University Senate. 9 pages

Emotional Responses To A Sexual Assault Threat: A Qualitative Analysis Among Women With Histories Of Sexual Victimization, Kristin E. Silver, Raeann E. Anderson, Amanda M. Brouwer

Psychology Faculty Publications

Sexual assaults against women are a leading threat to human rights and public health in the United States. Considering the high rates of sexual revictimization among women and the limited understanding of the mechanisms which fuel this phenomenon, the goal of the present study was to investigate the role of emotion in coping with a hypothetical threat of sexual assault for previously sexually victimized college women. A total of 114 college women with a history of sexual victimization listened to an audio-recording describing a sexual assault scenario and then described how they felt. A qualitative analysis paradigm was used to …

Volume 57, Number 27: February 26, 2020, University Of North Dakota

University Letter Archive

No abstract provided.

Febuary 25, 2020, The Dakota Student

The Dakota Student

No abstract provided.

Volume 57, Number 26: February 19, 2020, University Of North Dakota

University Letter Archive

No abstract provided.

Temporal Trends In The Standing Broad Jump Performance Of United States Children And Adolescents, Bridget K. Pinoniemi, Grant R. Tomkinson, Tanis J. Walch, James N. Roemmich, John S. Fitzgerald

Education, Health & Behavior Studies Faculty Publications

Purpose: To estimate temporal trends in broad jump performance for United States youth, a marker of muscular fitness and health.

Method: Electronic databases, topical systematic reviews, and personal libraries were systematically searched for studies reporting descriptive standing broad jump data for apparently healthy United States youth (age 10–17 years). Temporal trends at the sex-age level were estimated using sample-weighted regression models associating the year of testing to mean jump performance, with national trends standardized to the year 1985 using a post-stratified population-weighting procedure.

Results: Collectively, there was a small increase of 12.6 cm (95%CI: 12.5 to 12.7) or 7.9% (95%CI: …

Volume 57, Number 25: February 12, 2020, University Of North Dakota

University Letter Archive

No abstract provided.

Febuary 11, 2020, The Dakota Student

The Dakota Student

No abstract provided.

February 6, 2020, University Of North Dakota

University Senate Meeting Minutes

Minutes from the February 6, 2020, meeting of the University Senate. 3 pages

A Systematic Analysis Of Temporal Trends In The Handgrip Strength Of 2,216,320 Children And Adolescents Between 1967 And 2017, Faith L. Dooley, Tori Kaster, John S. Fitzgerald, Tanis J. Walch, Madison Annandale, Katia Ferrar, Justin J. Lang, Jordan J. Smith, Grant R. Tomkinson

Education, Health & Behavior Studies Faculty Publications

Objective: To estimate national and international temporal trends in handgrip strength for children and adolescents, and to examine relationships between trends in handgrip strength and trends in health-related and sociodemographic indicators.

Methods: Data were obtained through a systematic search of studies reporting temporal trends in the handgrip strength for apparently healthy 9–17 year-olds, and by examining large national fitness datasets. Temporal trends at the country-sex-age level were estimated by sample-weighted regression models relating the year of testing to mean handgrip strength. International and national trends were estimated by a post-stratified population-weighting procedure. Pearson’s correlations quantified relationships between trends in handgrip …

Volume 57, Number 24: February 05, 2020, University Of North Dakota

University Letter Archive

No abstract provided.

Febuary 4, 2020, The Dakota Student

The Dakota Student

No abstract provided.

An Exploration Of Correctional Counselor Workloads In A Midwestern State, Adam K. Matz, Nathan C. Lowe

Criminal Justice Faculty Publications

Time studies have been conducted with a variety of occupations. However, no known research has examined the workload of correctional counselors. The Iowa Department of Corrections, in partnership with the American Probation and Parole Association, performed the first known workload evaluation of this population. Over a hundred correctional counselors participated in a time study informed by a task analysis conducted with a representative advisory committee. The most common activities concerned inmate requests, classification, assessment, release planning, treatment group work, and administrative tasks. Most concerning, respondents indicated anywhere from 20-to-50% of the activities engaged in were unsatisfactorily completed.

Und Today: February 2020, University Of North Dakota

UND Today Archive

No abstract provided.

Role Of Endolysosomes And Inter-Organellar Signaling In Brain Disease, Zahra Afghah, Xuesong Chen, Jonathan David Geiger

Biomedical Sciences Faculty Publications

Endosomes and lysosomes (endolysosomes) are membrane bounded organelles that play a key role in cell survival and cell death. These acidic intracellular organelles are the principal sites for intracellular hydrolytic activity required for the maintenance of cellular homeostasis. Endolysosomes are involved in the degradation of plasma membrane components, extracellular macromolecules as well as intracellular macromolecules and cellular fragments. Understanding the physiological significance and pathological relevance of endolysosomes is now complicated by relatively recent findings of physical and functional interactions between endolysosomes with other intracellular organelles including endoplasmic reticulum, mitochondria, plasma membranes, and peroxisomes. Indeed, evidence clearly indicates that endolysosome dysfunction …

February 6, 2020: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the February 6, 2020, meeting of the University Senate. 13 pages

January 28, 2020, The Dakota Student

The Dakota Student

No abstract provided.

Volume 57, Number 22: January 22, 2020, University Of North Dakota

University Letter Archive

No abstract provided.

Metformin Uptake And Translocation In Chickpeas: Determination Using Liquid Chromatography−Mass Spectrometry, Brett Nespor, Anastasia Andrianova, Sean Pollack, Creighton Pfau, Muhammad Arifuzzaman, Nazrul Islam, Alena Kubatova, Khwaja Hossain

Chemistry Faculty Publications

Multiple chronic conditions (MCCs) such as diabetes, hypertension, heart disease, arthritis, asthma, and common respiratory problems are prevalent in over one-fourth of Americans, and separate drugs are prescribed to manage each of the diseases. The nutritive crop seeds loaded with multiple drugs could be a cheap and sustainable alternative to drugs produced by pharmaceutical companies. Our long-term goal is to produce chickpea seeds containing comparable dosages of multiple drugs regularly prescribed for managing MCC. In this work, we conducted experiments to understand the uptake and translocation of metformin into the tissues of chickpea to demonstrate the applicability of LC–HR-ToF-MS in …