Digital Commons Network^™

Ca2+ Entry Via Trpc1 Is Essential For Cellular Differentiation And Modulates Secretion Via The Snare Complex, Thad A. Rosenberger, Anne Schaar, Yuygang Sun, Pramod Sukumaran, Danielle Krout, James N. Roemmich, Lutz Brinbaumer, Kate Claycombe-Larson, Brij B. Singh

Biomedical Sciences Faculty Publications

Adipocyte functionality, including adipocyte differentiation and adipokine secretion, is essential in obesity-associated metabolic syndrome. Here, we provide evidence that Ca2+ influx in primary adipocytes, especially upon store-depletion, plays an important role in adipocyte differentiation, functionality, and subsequently metabolic regulation. The endogenous Ca2+ entry channel in both subcutaneous and visceral adipocytes was dependent on TRPC1-STIM1 and blocking Ca2+ entry with SKF-96365 or TRPC1-/- derived adipocytes inhibited adipocyte differentiation. Additionally, TRPC1-/- mice have decreased organ weight, but increased adipose deposition and reduced serum adiponectin and leptin concentrations, without affecting total adipokine expression. Mechanistically, TRPC1- mediated Ca2+ entry regulated SNARE complex formation and …

A Website Designed To Equip Occupational Therapists With Information And Strategies For Holistically Addressing Sexual Activity With The Geriatric Population, Amber Fernandez, Ashleigh Mora

Occupational Therapy Capstones

As individuals age, they are likely to experience occupational deprivation. Occupational deprivation occurs in many forms. Many older adults experience occupational deprivation relating to the activity of daily living, sexual activity. Older adults experience many age-related changes, which impacts their ability to engage in sexual activity. Health care professionals have a responsibility to ensure older adults are able to engage in safe sexual practices. Yet, healthcare professionals, including occupational therapists, are not addressing this need with their clients in a routine manner. A literature review was conducted in order to gain a comprehensive understanding of all the barriers older adults …

Life History Of Dr. Neil Harvison Phd, Otr, Fnap, Faota, Kaylee Loken, Bailey Schumacher

Oral History Student Papers

Objective: The purpose of study is to provide current and future generations of occupational therapists a view of the history and how occupational therapy practice has evolved from its inception to current practice through the life history stories of occupational therapists who have held leadership roles at the national level and beyond.

Method: The participant was selected from a participant list compiled through purposive sampling by the project directors. Informed consent was obtained prior to the interview. The project was reviewed by the UND Institutional Review Board and was exempted due to it being a life history. A semi-structured interview …

Is A Varicocelectomy Beneficial In The Era Of Assisted Reproductive Technologies?, Chukwuka Oscar Nnoli

Physician Assistant Scholarly Project Posters

Clinical varicoceles are the most frequent physical finding associated with infertile men and impaired semen parameters. There is evidence that suggests varicocele repair improves semen parameter and increases the chances of natural pregnancy. Today, varicocele repair is often combined with assisted reproductive techniques (ART) such as intrauterine insemination (IUI), in Vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). In this literature review, data examining whether varicocelectomy before ART leads to improved pregnancy outcomes is reviewed. Current data suggest that there is a significant clinical benefit when correcting a varicocele in oligospermic men before IVF/ICSI. Similarly, men with non-obstructive azoospermia also …

The Treatment Of Shoulder Dysfunction By The Correction Of Shouler Girdle Muscle Imbalances: A Case Study, Zachary Peterson

Physical Therapy Scholarly Projects

Background and Purpose: Shoulder dysfunction is a broad expression that encompasses the shoulder girdle not being able to perform fluently, without pain, or within normal ranges of motion. Current literature elaborates on potential causes of dysfunction such as: osteoarthritis, impingement syndrome, and cervical myelopathy. From a clinical standpoint, it is crucial to differentiate between possible diagnoses to ensure the proper treatment is utilized.

Case Description: The patient was a 66‐year‐old female who was referred with the initial diagnosis of shoulder osteoarthritis. She presented with headache pain that was debilitating and followed a pattern consistent with muscle guarding, limited L shoulder …

Evolution Of Occupational Therapy Practice: Life History Of Fred Sammons, Phd (Hon), Ot, Faota, Dalton Fetsch, Jonah Kratochvil

Oral History Student Papers

Objective: The purpose of the life history study of Fred Sammons, OT, is to provide current and future generations of occupational therapists a view of the history and how occupational therapy (OT) practice has evolved from its inception to current practice through the life history stories of occupational therapists who have held leadership roles at the national level and beyond. It is anticipated that the life history process will be a powerful way to gather this information.

Method: An in depth, semi-structured, 70-minute interview was conducted at the Goodstein Foundation Library on the campus of Casper College via …

Outpatient Physical Therapy Management Of A Patient Diagnosed With Myotonic Muscular Dystrophy Type 2, Ashley Jobe

Physical Therapy Scholarly Projects

Background and Purpose. This article describes the 3-week outpatient Physical Therapy management of a 63-year-old female with a diagnosis of Myotonic Muscular Dystrophy (MMD) Type 2. MMD is an inherited disorder, which progressively impacts muscular, respiratory, cardiac, nervous, and endocrine systems. MMD Type 2 is characterized by muscle weakness, muscle pain, and myotonia. The patient in this case study presented to physical therapy with upper and lower extremity weakness and balance impairment. The purpose of this article is to describe the initial physical therapy evaluation process for a patient with MMD, as well as the interventions used for this patient …

Exercise Compared To Ssris In The Treatment Of Major Depressive Disorder, Tiffany Fletschock

Physician Assistant Scholarly Project Posters

Major Depressive Disorder (MDD) is a common disease seen every day by primary care providers across the United States. According to the Centers for Disease Control and Prevention (CDC, 2018), eight percent of all adults over the age of 20 suffer from depression, and a study by the American Psychological Association found depressive disorders to cost roughly $71 billion annually. Today, psychotherapy is the recommended first-line therapy for treating MDD, but pharmacotherapy is more commonly used. Alternative forms of therapy are also being researched in order to avoid the use of medication while adequately treating the symptoms of MDD. For …

The Use Of Dhea In The Treatment Of Depression, Bryan Tipton

Physician Assistant Scholarly Project Posters

No abstract provided.

Electromyographic (Emg) Activity Of The Gluteus Medius During Various Hip Exercises, Kalie Maiden, Mitchell Karbo, Taylor Doeden, Analise Richtsmeier

Physical Therapy Scholarly Projects

Background and Purpose. The purpose of the study was to record and analyze muscle recruitment patterns of the gluteus medius and gluteus maximus muscles when performing a side lying abduction exercise requiring consistent force to roll a ball up and down the wall using the dominant lower extremity. Comparisons were made between the use of either a small, medium or large ball. The subjects performed a standing abduction exercises with theraband around both ankles as well.

Case Description. Fifteen subjects were recruited from the University of North Dakota Department of Physical Therapy to perform the four different types of exercises. …

Collaboration Between Physical Therapy And Music Therapy: A Case Study Of The Interventions And Their Effects On Parkinson's Disease, Mercedes Stein, Kristyn Bergh

Physical Therapy Scholarly Projects

Background and Purpose: Parkinson's Disease is a chronic and progressive neurological disorder that causes motor dysfunction leading to dyskinesia, bradykinesia, muscular rigidity, resting tremors, postural impairments, and gait impairments. These impairments can have a tremendous negative impact on a person's everyday life. This case study demonstrates the collaboration of physical therapy and music therapy interventions and its effects on a female with Parkinson's Disease.

Case Description: The patient is a 72-year old female diagnosed with Parkinson's Disease around 2010. Her primary reason for seeking treatment is due to an increase in freezing of gait and overall decrease in mobility that …

On The Interpretation Of The Normalization Constant In The Scaling Equation, Karl J. Niklas, Sean T. Hammond

Earth System Science and Policy Faculty Publications

The scaling equation, Y1 = βYα2, has been used empirically and explored theoretically primarily to determine the numerical value and meaning of the scaling exponent, α. The mathematical interpretation of α is clear—it is the quotient of the relative rate of change of Y1 with respect to the rate of change of Y2. In contrast, the interpretation of the normalization constant, β, is obscure, so much so that some workers have rejected the idea that it has any biological importance. With the notable exception of Steven J. Gould's early work, Huxley's dismissal of β largely relegated the study of its …

Finding Common Rules Of Robustness And Resilience That Span Multiple Levels Of Biological Organization, Robert Burnap, Jing Chen, Erica Crespi, Moumita Das, Rebecca Simmons, Zhen Wang, Jie Xiao, Bing Yang, John Yin

Biology Faculty Publications

Today, humans as a species face significant global challenges: meeting the needs of an ever expanding human population for food and energy from limited land, water and other resources; finding ways to counter rapidly changing pathogens that become resistant to current treatments; adapting to climate change that is linked to more frequent flooding, drought, wildfires and temperature extremes; and reversing the deterioration of ecosystems associated with human induced alterations of the environment. Owing to its resilience and robustness, life in one form or another will likely persist, but it is unknown by what mechanisms or in what forms. Much is …

The 20-M Shuttle Run: Assessment And Interpretation Of Data In Relation To Youth Aerobic Fitness And Health, Grant R. Tomkinson, Justin J. Lang, Joel Blanchard, Luc A. Léger, Mark S. Tremblay

Education, Health & Behavior Studies Faculty Publications

Cardiorespiratory fitness (CRF) is a good summative measure of the body’s ability to perform continuous, rhythmic, dynamic, large-muscle group physical activity, and exercise. In children, CRF is meaningfully associated with health, independent of physical activity levels, and it is an important determinant of sports and athletic performance. Although gas-analyzed peak oxygen uptake is the criterion physiological measure of children’s CRF, it is not practical for population-based testing. Field testing offers a simple, cheap, practical alternative to gas analysis. The 20-m shuttle run test (20mSRT)—a progressive aerobic exercise test involving continuous running between 2 lines 20 m apart in time to …

Grit Of First- And Second-Year Physical Therapy Students: A Pilot Study, Brianne Halbur, Alison Kopp

Physical Therapy Scholarly Projects

Background and Purpose: The purpose of this pilot study was to compare year-one and yeartwo student physical therapists grit scores using Angela Duckworth's 12 question Grit survey to investigate if there were correlations between the Grit score, GPA, age, or gender. The results of this pilot study will help shape further research on using Grit score as an indicator for academic success and hardship for students in strenuous programs.

Methods: The Grit-0 scale was distributed to both second and first year Doctor of Physical Therapy (DPT) students at the University of North Dakota by the primary investigator. There were 105 …

The Effects Of An Early Motion Protocol For Rehabilitation Following A Massive Rotator Cuff Tear Repair: A Case Report, Kody Strum

Physical Therapy Scholarly Projects

Background and Purpose: Rotator cuff tears are one of the most common musculoskeletal injuries to occur in the United States. Following a surgical repair, there are two main rehabilitation protocols: early motion and delayed motion. Despite the large number of patients in need of rehab following a rotator cuff tear surgical repair, there is not yet a definitive answer in the literature as far as the best protocol to use.

Case Description: The patient was a 68-year-old male who injured himself while slipping and attempting to catch himself with his right arm. He presented to physical therapy following a surgical …

Case Study: Acute And Subacute Physical Therapy Management Of Patient With Multiple Orthopedic Injuries And A Mild Brain Injury Resulting From Motorcycle Collision, Leah Jensen

Physical Therapy Scholarly Projects

Background and Purpose. This case report describes the 3.5-week inpatient physical therapy management of an 18-year-old female involved in a motorcycle accident resulting in multiple orthopedic injuries, a mild brain injury, and multiple skin abrasions. She was non-weight bearing (NWB) with her bilateral upper extremities, toe-touch weight bearing (TTWB) on her right lower extremity, and weight bearing as tolerated (WBAT) on her left lower extremity throughout the course of her treatment. The purpose of this case report is to describe the various physical therapy (PT) interventions utilized for this patient and the patient's status after completion of them.

Case Description. …

Physical Therapy Rehabiliation For Lumbar Radiculopathy: A Case Report, Rebecca Lynch

Physical Therapy Scholarly Projects

Background and Purpose. Lumbar radiculopathy is one of the most common orthopedic conditions. This occurs when there is damage to a nerve root in the area that it exits the spinal cord. This can be caused from a disc herniation bone spurs, trauma, or a mechanical stretching event. There is not consistent evidence in current literature regarding rehabilitation interventions for this condition.

Case Description. This case report describes a 62-year-old female presenting to physical therapy with lumbar radiculopathy symptoms. She had multiple comorbidities as well as a scheduled total knee replacement surgery. Physical therapy interventions for this patient included manual …

Accessibility And Perceived Value Of Pre-Admission Clinical Contact Hours: Physical Therapy Clinician Perspectives, Riley Wilson

Physical Therapy Scholarly Projects

Purpose: This study analyzes the accessibility and perceived value of contact hours prior to a student's acceptance to a professional physical therapy (PT) program from clinicians' perspective. There is limited research regarding the effectiveness of pre-admission clinical contact hours in PT. The results may help the conversation on whether contact hours should be a requirement prior to acceptance into a program, and the impact the requirement may have on practicing clinicians.

Methods: This study utilized an electronic survey sent to the chairpersons or Directors of Clinical Education of 1-2 accredited programs in each state (n=48) that has a PT program, …

Physical Therapy Treatment For A Patient With A Hip Fracture And Cognitive Impairments: A Case Report, Tracie Boehmlehner

Physical Therapy Scholarly Projects

Background and Purpose: As the population shifts to include higher numbers of people in the elderly population, diseases and pathologies associated with geriatric populations will also increase. Two of these conditions are cognitive impairment and hip fractures. Hip fractures can be costly and life altering injuries. Treating patients with both of these conditions can pose a unique challenge to healthcare workers.

Case Description: The patient in this case study is a 78 year-old female who suffered a hip fracture secondary to a fall with a hip herniarthroplasty completed. She had many co-morbidities that are typical of an aging person such …

Enabling Occupational Competence Through Stress Reduction For Parents In The Neonatal Intensive Care Unit (Nicu), Jenna Nelson, Rachel Trieff

Occupational Therapy Capstones

Each year, thousands of infants are admitted to the Neonatal Intensive Care Unit (NICU). Research has shown evidence that parents, of babies who are admitted to the NICU, experience increased stress levels and are at an increased risk for mental health issues after discharge from the hospital. The objective of this scholarly project was to develop an occupation-based group protocol that focuses on enabling an occupational adaptive response for parents in the NICU, through the use of evidenced-based stress reduction techniques. An extensive literature review was conducted to identify research to be used to support the development of this product. …

Evolution Of Occupational Therapy Practice: Life History Of Dr. Barbara L. Kornblau, Jd, Otr/L, Faota, Daspe, Ccm, Cdms, Cpe, Abby Wavra, Kelsey Sherry

Oral History Posters

This paper is a summary of an interview completed with Dr. Barbara L. Kornblau. Barbara is a licensed occupational therapist and lawyer who was interviewed by two occupational therapy students at the University of North Dakota as a part of a larger life history qualitative study that included 30 total participants. This study was done to gather an understanding of her experience in occupational therapy (OT). The interview was semi-structured and lasted approximately 90 minutes, followed by a transcription and data analysis used to organize the information into twelve codes and six emerging themes. This single interview is a part …

The Evolution Of Occupational Therapy: Life History Of Shirley A. Wells, Drph, Otr, Faota, Hope Schuster, Hailey Johnson

Oral History Posters

Objective: The purpose of the life history of Dr. Shirley Wells is to gain an insight about her life experiences and leadership throughout her years of work in the profession of occupational therapy.

Method: An in-depth, semi-structured, hour and a half interview was conducted via the telecommunication app, Zoom. The interview was later transcribed verbatim and coded for the emergent categories and corresponding themes.

Results: The predominant categories representing the major elements of her life history were overcoming challenges, providing a seat at the table, and developing practice. The findings indicate that she made a significant impact for …

Multi-Band Optical And Near-Infrared Properties Of Faint Submillimeter Galaxies With Serendipitous Alma Detections, Pallavi Patil, Kristina Nyland, Mark Lacy, Duncan Farrah, José Afonso, Wayne A. Barkhouse, Jason Surace

Physics Faculty Publications

We present a catalog of 26 faint submillimeter galaxies (SMGs) in the XMM Large Scale Structure (XMM-LSS) field identified by cross-matching serendipitously detected sources in archival pre–Atacama Large Millimeter Array (ALMA) band 6 and 7 data with multiband near-infrared (NIR) and optical data from the Spitzer Extragalactic Representative Volume Survey, the VISTA Deep Extragalactic Survey, the Canada–France–Hawaii Telescope Legacy Large Survey, and the Hyper Suprime-Cam Subaru Strategic Program. Of the 26 SMGs in our sample, 15 are identified here for the first time. The majority of the sources in our sample (16/26) have faint submillimeter fluxes (0.1 mJy < S 1mm …

The Use Of Dehydroepiandrosterone For Treatment Of Depression, Bryan Tipton

Physician Assistant Scholarly Project Papers

Dehydroepiandrosterone (DHEA) and its sulfated ester (DHEA-S) are important pre-hormones that also have direct neurohormonal effects on the central nervous system. Over the last twenty years, data have revealed that serum DHEA peaks in a person’s mid-20s and steadily declines throughout their lifetime. In addition, women tend to have lower values than men. This is of note because lower serum values tend to be correlated with increased risk of depression, worse depressive symptoms, and increased risk of relapse into depression. A review of literature concerning DHEA’s age related values, its association with depression, and its use in the treatment of …

Exercise Compared To Ssris In The Treatment Of Major Depressive Disorder, Tiffany Fletschock

Physician Assistant Scholarly Project Posters

Major Depressive Disorder (MDD) is a common disease seen every day by primary care providers across the United States. According to the Centers for Disease Control and Prevention (CDC, 2018), eight percent of all adults over the age of 20 suffer from depression, and a study by the American Psychological Association found depressive disorders to cost roughly $71 billion annually. Today, psychotherapy is the recommended first-line therapy for treating MDD, but pharmacotherapy is more commonly used. Alternative forms of therapy are also being researched in order to avoid the use of medication while adequately treating the symptoms of MDD. For …

Is A Varicocelectomy Beneficial In The Era Of Assisted Reproductive Technologies, Chukwuka Oscar Nnoli

Physician Assistant Scholarly Project Posters

Clinical varicoceles are the most frequent physical finding associated with infertile men and impaired semen parameters. There is evidence that suggests varicocele repair improves semen parameter and increases the chances of natural pregnancy. Today, varicocele repair is often combined with assisted reproductive techniques (ART) such as intrauterine insemination (IUI), in Vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). In this literature review, data examining whether varicocelectomy before ART leads to improved pregnancy outcomes is reviewed. Current data suggest that there is a significant clinical benefit when correcting a varicocele in oligospermic men before IVF/ICSI. Similarly, men with non-obstructive azoospermia also …

The Effect Of Barefoot Running On Navicular And Pelvic Drop: A Randomized Controlled Trial, Alyssa Sandry, Danielle Gamel, Ryan Cook

Physical Therapy Scholarly Projects

Background and Purpose: Gaining knowledge of the change in navicular drop of the foot and pelvic movement in response to barefoot running training may allow sports medicine professionals, coaches, athletes, and others in the healthcare field to decrease the amount of injuries that may be caused by these motions. Effects of a running training program with conversion from a rearfoot strike pattern (RFSP) to forefoot strike pattern (FFSP) to determine impact on navicular drop and pelvic movement is lacking in literature. Due to the increased correlation of hip movement and lower extremity injuries, the purpose of this study was to …

Effects Of Pole Walking On Older Adults Following Six Weeks Of Training, Samantha Forsch, Raevyn Haugland

Physical Therapy Scholarly Projects

Introduction: Age-related changes in adults over 60 include reduced mobility and function as well as an increase in frailty. Conventional walking has been shown to be an effective physical activity to maintain mobility and improve function and overall health and fitness. Specifically, walking speed has been identified as a crucial predicting factor for fall risk and decreased functional mobility. For this reason, clinicians considered the element of walking speed as the sixth vital sign. Pole walking has gained popularity over the years and may provide additional benefits, when compared to conventional walking, such as improved stride and step length, faster …

Potentials Of Physiological Signals To Implement A Wearable Drowsiness Detection And Warning System For Pilots, Shubha Majumder

Theses and Dissertations

Drowsiness is a transitional psychophysiological state from alertness towards sleep, which decreases concentration and increases response time. Drowsiness during duty hours is common for in-flight pilots due to frequent travel across different time zones, extended duty hours as well as circadian rhythm disruption. Hence, drowsy flying is one of the leading reasons for increased risk of accidents, especially in commercial aviation. Mainly three approaches (i.e., vehicle-based, behavioral, and physiological signal based) are used for onboard drowsiness detection. Among them, physiological signal-based approach is advantageous for early detection of drowsiness with reasonable accuracy due to the strong relationship among some of …