Digital Commons Network^™

20231215_Hslic's Collection Development Manual Approved, Robyn Gleasner

HSLIC Blog Post

No abstract provided.

Hsc Connects Newsletter - December 15, 2023, Unm Hsc Communications

HSC Connects Newsletters

Weekly newsletter of the UNM Health Sciences Center.

Aleukemic Chronic Myeloid Leukemia Without Neutrophilia And Thrombocytosis: A Report From The Bcr::Abl1 Pathology Group, Daniel Rivera, Wei Cui, Juehua Gao, Deniz Peker, Qian-Yun Zhang, Rajan Dewar, Lianqun Qiu, Sergej Konoplev, Zhihong Hu, Koji Sasaki, Aileen Y. Hu, Shuyu E, Meng Liu, Hong Fang, Wei Wang, Guilin Tang, Jane F Apperley, Andreas Hochhaus, Jorge E. Cortes, Joseph D. Khoury, L Jeffrey Medeiros, Elias Jabbour, Shimin Hu

Pathology Research and Scholarship

Chronic myeloid leukemia (CML) is characterized by leukocytosis with left-shifted neutrophilia, basophilia, eosinophilia, and variable thrombocytosis. However, extremely rare cases of patients with CML without significant leukocytosis and thrombocytosis (aleukemic phase [ALP] CML, or CML-ALP) have been reported. Due to its rarity and limited awareness, there remains a significant knowledge gap concerning the pathologic diagnosis, disease progression, and optimal patient management and outcomes. In this multi-institutional study, we investigated 31 patients with CML-ALP. Over half (54.8%) of patients had a history of or concurrent hematopoietic or nonhematopoietic malignancies. At time of diagnosis of CML-ALP, approximately 26.7% of patients exhibited neutrophilia, …

Environmental Ozone Exposure, Gestational Health, And The Lung-Placental Axis, Russell Hunter

Biomedical Sciences ETDs

Adverse gestational outcomes of pregnancy are a globally occurring threat to fetomaternal health, with limited clinical prognostic and intervention strategies aside from premature labor induction. Epidemiological data shows strong correlations between gestational exposure to air pollution and the incidence of adverse gestational outcomes. The research presented here was designed to evaluate potential murine models of gestational exposure, as well as quantify maternal cardiovascular damage therein. These studies employ radiotelemetry, echocardiography, single cell RNA-sequencing, and untargeted lipidomic analyses in efforts to study these effects. Results implicate cardiovascular responses to mid-gestational ozone exposure as evidenced by decreased maternal cardiac output and increased …

The 2005 Bosnian Law On Defense; A Policy Change Case Study, Gregory D. Vuksich

Political Science ETDs

The Dayton Peace Accord (DPA) in 1995 ended the civil war in Bosnia and Hercegovina and established a constitution for the newly institutionalizing state. It permitted the three ethnicities – Bosniaks, Croats and Serbs – to retain their wartime armed forces in place under ethnic command, a prerogative the Serbs guarded strenuously. International organizations, however, sought a single, multiethnic military institution for the whole of the country. In 2005, however, the Serbs reversed their opposition and agreed to the international organization preference. This study explores why Bosnia’s Serbian community reversed its earlier and acceded to the creation of a single …

Interrogation Of The Molecular Mechanisms That Finetune Fcεri Signaling And Mast Cell Outcomes, Derek A. Rinaldi

Biomedical Sciences ETDs

FcεRI is the ITAM receptor primarily responsible for the allergic response and immune hypersensitivity diseases such as asthma. Regulation of the strength of both FcεRI signaling, and the resulting outcomes, is accomplished via a complex array of molecular mechanisms whose interactions remain unclear. Here, I explored how the biophysical properties of antigens, crosstalk between FcεRI and integrin signaling and Arf6-mediated control of trafficking and exocytosis tune mast cell outcomes. I first found significant differences in FcεRI aggregation, phosphorylation and granule secretion after crosslinking with the multivalent antigen DNP-BSA or the small, trivalent antigen DF3. I also revealed a bi-directional, Syk-mediated …

A Descriptive Analysis Of Fatal Outcomes In Immune Thrombotic Thrombocytopenic Purpura In The Ustma Ttp Registry, Mouhamed Yazan Abou-Ismail, Chong Zhang, Angela Presson, Shruti Chaturvedi, Ana G. Antun, Andrew Farland, Ryan Woods, Ara Metjian, Yara Park, Gustaaf De Ridder, Briana Gibson, Raj S. Kasthuri, Darla K. Liles, Frank Akwaa, Todd Clover, Lisa Baumann Kreuziger, Meera Sridharan, Ronald S. Go, Keith R. Mccrae, Harsh Vardhan Upreti, Radhika Gangaraju, Nicole Katlyn Kocher, X Long Zheng, Jay S. Raval, Camila Masias, Spero R. Cataland, Andrew David Johnson, Elizabeth Davis, Michael D. Evans, Marshall Mazepa, Ming Y. Lim

Pathology Research and Scholarship

No abstract provided.

Racialized Masculinities In Professional Basketball: Utilizing Mixedness To Challenge Commonplace Black/White Media Discourses About Nba Players, Anthony C. Peavy

Communication ETDs

In this dissertation project, I utilize a Critical Mixed Race Studies (CMRS) lens to examine how mixed-race Black/White players in the National Basketball Association (NBA) are represented, discussed, racialized, and gendered by major sports media platforms. More specifically, I utilize this project to elucidate how media centered on professional basketball continue to partake in hegemonic and essentialist rhetoric surrounding Black and White masculinity—that which has been used to discuss Black and White men in basketball throughout the entire history of the sport—to homogenize mixed-race Black/White men in the NBA and present them in a way that diminishes the potentially deconstructive …

12/11/2024 Meeting, Varina A. Kosovich

Meeting Minutes

No abstract provided.

Electrodeposition Of Giant Magnetostrictive Transducers For A Fabricated Mixed Physics Signal Transmission Device, Mina Faltas

Nanoscience and Microsystems ETDs

Non-intrusive solutions for communication through a sealed metal vessel requires the use of piezoelectric transducers to transmit acoustic waves through the vessel wall. This approach suffers the disadvantage of compromised security because a potential eavesdropper could decipher the correlation between digital and electric signals of both sides of the system. One solution is a mixed physics system employing magnetostrictive transducers.

For a magnetostrictive transducer to work well in this application, it would have to have a high piezomagnetic constant. This is influenced by soft magnetism and saturation magnetostriction. Nickel-Iron-Cobalt alloys are modified to retain their soft magnetic properties while increasing …

Amicus Curiae Brief Of The Navajo Nation, Paul Spruhan

Faculty Scholarship

The Navajo Nation Labor Commission ("NNLC" or "Commission") invited the Navajo Nation Department of Justice ("DOJ") to file an amicus brief in this matter. As discussed more fully below, the DOJ recommends that the NNLC hold an evidentiary hearing to gather facts necessary to conduct a full jurisdictional analysis under Montana and determine whether the Northern Apache County Special Healthcare District ("NACSHCD") has sovereign immunity. The fact gathering process is necessary given the fact-intensive analysis under both Montana and Arizona's sovereign immunity laws. As the Navajo Supreme Court has instructed, the proper threshold inquiry is whether jurisdiction exists over the …

12-07-2023 Hsc Committee Minutes, Helen Maestas

HSC Committee (A subcommittee of the UNM Board of Regents)

12-07-2023 HSC Committee Meeting Minutes

Liquid Biopsy: From Concept To Clinical Application, Catherine Alix-Panabières, Dario Marchetti, Julie E. Lang

Pathology Research and Scholarship

The diagnosis and treatment of cancer presents a physical and mental burden to the patient, often involving diagnostic biopsies and surgeries or chemotherapeutic approaches with severe side-effects. Advances which enable early detection of cancer and close monitoring of the disease course without invasive procedures, and which can underpin a tailored approach to treatment, can therefore make a big difference to the quality of life of patients. Liquid biopsies can be used to access tumor cells and tumor DNA circulating in the blood. Monitoring these species can provide a minimally invasive and repeatable means to detect cancer, or gain information about …

Ai In Higher Education And Research, Leo Lo, Laura J. Hall

Biomedical Informatics Seminar Series (BioMISS)

Description:

Artificial Intelligence holds great promise for higher education from helping students learn more efficiently to entering the job market better prepared for the future. It’s also transforming the way in which faculty conduct research. This session of the BioMISS seminar series will focus on AI trends and explore application in research.

Learning Objectives

1. Learn about how generative AI is being integrated into higher education, with some specific examples from initiatives at the University of New Mexico (UNM).
2. Gain a greater understanding of generative AI capabilities and limitations.
3. Insight into the importance of critically assessing information produced by AI …

Laii Open House: Zine And Podcast Release Party, Latin American And Iberian Institute

LAII Events

Join us as we celebrate the end of the semester. Some of our LAS students will present their final projects and food will be served!

20231206_New Materials At Hslic, Moses L. Moya

HSLIC Blog Post

No abstract provided.

20231206_Joseph V. Scaletti Papers Processed, Abbie Weiser

HSLIC Blog Post

No abstract provided.

Reclaiming Indigenous History: Pyroepistomology And Social Justice, Paulette Steeves

LAII Events

The Indigenous past of the Americas has been fabricated to fit into neoliberal time frames of imagined “New Worlds". The past remains a tool of dis-empowerment created by American archaeologists to keep Indigenous civilizations as “infantile” on a global scale. In the Americas, the deep Indigenous past prior to 12,000 years before the present has been aggressively denied for over a century. Anthropologists’ denial of the deep Indigenous past of the Americas, has cleaved Indigenous people’s links to their homeland and created them as recent immigrants to the Americas, on a global scale of human history. Yet, Indigenous oral traditions …

20231205_Library’S Entry-Level Floor Is Getting A Refresh!, Sally Bowler-Hill

HSLIC Blog Post

No abstract provided.

20231204_Fuel For Finals December 4th-8th, Varina Kosovich

HSLIC Blog Post

No abstract provided.

A Review On Possible Physical Meaning Of Elastic-Electromagnetic Mathematical Equivalences, Florentin Smarandache, Victor Christianto

Branch Mathematics and Statistics Faculty and Staff Publications

It is known, despite special theory of relativity has been widely accepted, in our recent draft submitted to this journal it is shown that some experiments have been carried out suggesting superluminal wave propagation, which make Minkowski lightcone not valid anymore. Therefore, it seems worth to reconsider the connection between elastic wave and electromagnetic wave equations, as in their early development. In this paper we will start with Maxwell-Dirac isomorphism, then we will find its connection with elastic wave equations.

Preferences For Cpstf-Recommended Intervention Approaches For Increasing Cancer Screening Among Screen-Eligible Adults In Zuni Pueblo, Usa., Nicholas Edwardson, Mikaela Kosich, V Shane Pankratz, Judith Sheche, Kate Cartwright, Deborah Kanda, Samantha Leekity, Shiraz I. Mishra

Pediatrics Research and Scholarship

We identified preferences toward Community Preventive Services Task Force (CPSTF)-recommended intervention approaches among screen-eligible Zuni Pueblo members in New Mexico, USA and assessed if there were significant differences in those preferences, with the goal of informing the selection of intervention approaches for use in the Zuni Pueblo. We utilize data from a population-based survey (n = 280) focused on 15 CPSTF-recommended intervention approaches designed to improve screening for cervical, breast, and/or colorectal cancer screening. Model-adjusted results suggest some intervention approaches garnered significantly higher support than others. We offer six, data-driven recommendations for consideration by public health practitioners as they endeavor …

Preferences For Cpstf-Recommended Intervention Approaches For Increasing Cancer Screening Among Screen-Eligible Adults In Zuni Pueblo, Usa, Nicholas Edwardson, Mikaela Kosich, V Shane Pankratz, Judith Sheche, Kate Cartwright, Deborah Kanda, Samantha Leekity, Shiraz I Mishra

Pediatrics Research and Scholarship

We identified preferences toward Community Preventive Services Task Force (CPSTF)-recommended intervention approaches among screen-eligible Zuni Pueblo members in New Mexico, USA and assessed if there were significant differences in those preferences, with the goal of informing the selection of intervention approaches for use in the Zuni Pueblo. We utilize data from a population-based survey (n = 280) focused on 15 CPSTF-recommended intervention approaches designed to improve screening for cervical, breast, and/or colorectal cancer screening. Model-adjusted results suggest some intervention approaches garnered significantly higher support than others. We offer six, data-driven recommendations for consideration by public health practitioners as they endeavor …

Salivary Duct Carcinoma Arising In A Warthin Tumor Of The Parotid Gland: A Rare Case Report With Review Of Literature And Pd-L1 Expression, Kaitlyn J. Nielson, Gamaliel Lorenzo, Shweta Agarwal

Pathology Research and Scholarship

Warthin's tumor is the second most common neoplasm of the parotid gland and consists of 2 components, including lymphoid stroma and glandular epithelium. Malignant transformation in this tumor is mostly seen in the lymphoid component; however, the carcinomatous transformation of the epithelial component is extremely rare. Cases of latter reported in the literature include squamous cell carcinoma, adenocarcinoma, mucoepidermoid carcinoma, oncocytic carcinoma, Merkel cell carcinoma, and undifferentiated carcinoma. We describe an extremely rare case of salivary duct carcinoma arising in a Warthin tumor in a 64-year-old male. Patient presented with an enlarging left parotid mass, biopsy of which showed salivary …

Iron Promotes Glycolysis To Drive Colon Tumorigenesis., Zhaoli Liu, Luke Villareal, Lavanya Goodla, Hyeoncheol Kim, Daniel M. Falcon, Mohammad Haneef, David R. Martin, Li Zhang, Ho-Joon Lee, Daniel Kremer, Costas A. Lyssiotis, Yatrik M. Shah, Henry C. Lin, Hui-Kuan Lin, Xiang Xue

Pathology Research and Scholarship

Colorectal cancer (CRC) is the third most common cancer and is also the third leading cause of cancer-related death in the USA. Understanding the mechanisms of growth and progression of CRC is essential to improve treatment. Macronutrients such as glucose are energy source for a cell. Many tumor cells exhibit increased aerobic glycolysis. Increased tissue micronutrient iron levels in both mice and humans are also associated with increased colon tumorigenesis. However, if iron drives colon carcinogenesis via affecting glucose metabolism is still not clear. Here we found the intracellular glucose levels in tumor colonoids were significantly increased after iron treatment.

20231201_On The Road With Hslic Outreach, Deirdre Caparoso

HSLIC Blog Post

No abstract provided.

Godel, Escherian Staircase And Possibility Of Quantum Wormhole With Liquid Crystalline Phase Of Iced-Water - Part I: Theoretical Underpinning, Victor Christianto, T. Daniel Chandra, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

As a senior physicist colleague and our friend, Robert N. Boyd, wrote in a journal (JCFA, Vol. 1,. 2, 2022), Our universe is but one page in a large book [4]. For example, things and Beings can travel between Universes, intentionally or unintentionally. In this short remark, we revisit and offer short remark to Neil’s ideas and trying to connect them with geometrization of musical chords as presented by D. Tymoczko and others, then to Escher staircase and then to Jacob’s ladder which seems to point to possibility to interpret Jacob’s vision as described in the ancient book of Genesis …

Godel, Escherian Staircase And Possibility Of Quantum Wormhole With Liquid Crystalline Phase Of Iced-Water - Part Ii: Experiment Description, Victor Christianto, T. Daniel Chandra, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The present article was partly inspired by G. Pollack’s book, and also Dadoloff, Saxena & Jensen (2010). As a senior physicist colleague and our friend, Robert N. Boyd, wrote in a journal (JCFA, Vol. 1, No. 2, 2022), for example, things and Beings can travel between Universes, intentionally or unintentionally [4]. In this short remark, we revisit and offer short remark to Neil Boyd’s ideas and trying to connect them with geometry of musical chords as presented by D. Tymoczko and others, then to Escherian staircase and then to Jacob’s ladder which seems to pointto possibility to interpret Jacob’s vision …

Extremum Seeking Control Algorithms For Extremely High Frequency Antenna System Pointing, Scott Shore

Mechanical Engineering ETDs

The research examines the application of extremum seeking control (ESC) algorithms to ground station antenna pointing for extremely high frequency (EHF) communication systems. ESC algorithms search for local maxima or minima by locating where an objective function gradient goes to zero. With wireless communication expanding into higher frequencies, the ground station pointing requirement is increasing. ESC presents a method which utilizes available equipment and information to perform ground station pointing. Additionally, ESC algorithms do not rely on assumptions or approximations needed for other techniques. The dissertation demonstrates ESC algorithm feasibility for the ground station pointing problem, benchmarks the ESC algorithms …

Post-Wildfire Export Regimes Of Solutes Along The Gallinas-Pecos River-Santa Rosa Fluvial Network, Asmita Kaphle

Civil Engineering ETDs

Wildfires significantly contribute to water pollution when ash and sediments, including nutrients and metals, are released into fluvial systems, impacting aquatic ecosystems and surrounding communities. This study focuses on the impacts of the Hermits Peak-Calf Canyon Fire on the Gallinas and Pecos watersheds. It employs five monitoring stations along a 190km fluvial network to assess solute export regimes post-fire, where grab samples were collected for nutrient and metal analyses for a period of more than a year. The metrics used for characterizing mobilization, chemostatic, or dilution patterns indicated mobilization for most solutes at all sites upstream of Santa Rosa Lake. …