Digital Commons Network^™

Mechanisms Of Arsenic-Induced Suppression Of Early Red Blood Cell Development, Sebastian Medina

Biomedical Sciences ETDs

Anemia adversely impacts the health of more than a billion people worldwide. A strong association between anemia and arsenic exposure has been reported in epidemiological studies from multiple countries. However, the mechanistic bases for the association between arsenic exposure and anemia is not fully understood. In this study, we found an inverse association between drinking water arsenic exposures and clinical indicators of anemia (i.e., red blood cell counts and hematocrit/packet cell volumes) in a cohort of men from rural Bangladesh enrolled in the Health Effects of Arsenic Longitudinal Study.

Follow-up studies in mice, revealed that 60-day exposure to trivalent inorganic …

Informativeness Of Dental Morphology In Ancestry Estimation In African Americans, Jessica M. Gross, Heather J H Edgar

Pathology Research and Scholarship

OBJECTIVES: Our objective is to assess the informativeness of dental morphology in estimating biogeographic ancestry in African Americans.

MATERIALS AND METHODS: The data are 62 dental morphological traits scored as nondichotomized and dichotomized in 797 individuals, 992,601 SNPs from 271 individuals, and 645 STRs from 177 individuals. Each dataset consists of Africans, Europeans, and African Americans. For each dataset, we summed Fisher Information (FI), then used STRUCTURE to estimate ancestry.

RESULTS: Total FI was highest for SNPs, followed by STRs, nondichotomized dental traits, and dichotomized dental traits. For both genetic datasets, Africans and Europeans fell into two distinctive clusters with …

Genetic Associations Of Hemoglobin In Children With Chronic Kidney Disease In The Pedigfr Consortium, Meredith A Atkinson, Rui Xiao, Anna Köttgen, Elke Wühl, Craig S Wong, Matthias Wuttke, Aysun K Bayazit, Salim Çalişkan, Bradley A Warady, Franz Schaefer, Susan L Furth

Pediatrics Research and Scholarship

BACKGROUND: Genome-wide association studies (GWAS) in healthy populations have identified variants associated with erythrocyte traits, but genetic causes of hemoglobin variation in children with CKD are incompletely understood.

METHODS: The Pediatric Investigation of Genetic Factors Linked with Renal Progression (PediGFR) Consortium comprises three pediatric CKD cohorts: Chronic Kidney Disease in Children (CKiD), Effect of Strict Blood Pressure Control and ACE Inhibition on the Progression of CRF in Pediatric Patients (ESCAPE), and Cardiovascular Comorbidity in Children with CKD (4C). We performed cross-sectional and longitudinal association studies of single-nucleotide polymorphisms (SNPs) in 1125 patients.

RESULTS: Children of European (n = 725) or …

02-05-19 Hsc Committee Meeting Agenda (Revised), Hsc Committee

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Remark On Creatio Ex Nihilo, Intelligent Design And Emergence Philosophy Approaches To Origin Of The Universe, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

It is known that the Big Bang theory was based on the concept of creation ex nihilo, after ancient Greek philosophers. In this paper, we will make few remark on the concept of creatio ex nihilo (as a commentary to a recent paper by Kalachanis, Athanasios Anastasiou, Ioannis Kostikas, Efstratios Theodossious and Мilan S. Dimitrijevi), as well as two other approaches, i.e. Intelligent Design and Emergence Theory by Clayton/Yong. As continuation of our recent paper to appear in forthcoming issue of J. Asia Mathematika, we argue that beside the above three approaches, a new concept called creatio ex-rotatione offers a …

Reaction Of Titanium Subhydride With Multiple Passivating Gasses, Erik C. Strobert Jr

Chemical and Biological Engineering ETDs

Sandia National Laboratories has used substoichiometric titanium hydride as a pyrotechnic fuel for decades. Production of titanium subhydride requires partial dehydriding of titanium hydride powder and subsequent chemical passivation to render the resultant bare titanium surface nonreactive and the powder non-pyrophoric. Novel passivation techniques, using a gas other than air, have been suggested in the past but have never been investigated. This work examines the reaction kinetics of titanium subhydride with three passivating agents, nitrogen, oxygen, and propane. These passivation experiments took place under isothermal conditions (420 ˚C) with varied dehydriding and passivation time periods. It was found that the …

Submittal Of The Mixed Waste Landfill Five-Year Report, Sandia National Laboratories/New Mexico, Epa Id Number Nm5890110518, January 2019, Sandia National Laboratories/Nm Snl

Facilities-Units

The Department of Energy/National Nuclear Security Administration (DOE/NNSA) and Sandia National Laboratories /New Mexico (SNL/NM) personnel submitted the Mixed Waste Landfill (MWL) Five-Year Report for the January 2014 through December 2017 reporting period to the New Mexico Environment Department (NMED) in accordance with the requirements of Section 4.8.2 of the MWL Long-Term Monitoring and Maintenance Plan (LTMMP). The LTMMP became effective on January 8, 2014 and the first Five-Year Report was due January 8, 2019.

The MWL is a 2.6-acre Solid Waste Management Unit (SWMU 76) located in the north-central portion of SNL/NM Technical Area III that has undergone corrective …

Understanding And Improving Patient Satisfaction In Orthopaedic Surgical Procedures: A Review, Paul J. Johnson

UNM Orthopaedic Research Journal

Orthopaedic surgeons and their hospitals are being evaluated and reimbursed according to their ability to provide patient satisfaction. It behooves physicians to learn how patient satisfaction is evaluated, how patient satisfaction may be improved, and how improvements in patient satisfaction may positively influence patient outcomes both subjectively and objectively. The purpose of this review is to illuminate how evaluation works, how patient factors may affect or correlate with increased satisfaction, and how physicians can improve actions to enhance patient satisfaction. Notably, studies have found that improved care coordination, nursing follow-up, provider listening skills, providing realistic yet positive expectations, and sitting …

Periprosthetic Joint Infections: A Review, Jay J. Wojcik

UNM Orthopaedic Research Journal

No abstract provided.

Design For Transtibial Modifiable Socket For Immediate Postoperative Prosthesis, Matthew N. Rush, Evan Hagin, Jane Nguyen, Victoria Lujan, Rebecca A. Dutton, Christina Salas

UNM Orthopaedic Research Journal

Amputations are long-standing surgical procedures that have been performed for centuries; however, very little attention and urgency have been given to immediate restoration of movement and return to a normal lifestyle. In many cases, the time between amputation and prosthetic fitting can pause recovery and development of new routines. To increase recovery, immediate postoperative prostheses (IPOPs) have been developed yet these are under-utilized because of concerns for wound healing and complications with vascular diseases. Subsequently, we designed a transtibial IPOP that utilizes an ergonomic modifiable socket that allows for examination, wound care, and in situ edema control. Additionally, the IPOP …

Fellows And Chiefs, Unm Department Of Orthopaedic Surgery

UNM Orthopaedic Research Journal

No abstract provided.

Division Of Research, Unm Department Of Orthopaedic Surgery

UNM Orthopaedic Research Journal

No abstract provided.

Middle Rio Grande Conservation Action Plan: Framework And Status Assessment, Colorado Natural Heritage Program, Colorado State University, Natural Heritage New Mexico, Biology Department, Unm, Museum Of Southwestern Biology, Unm

Middle Rio Grande Conservation Action Plan Symposium (2019)

No abstract provided.

Outcomes And Suggested Next Steps From The 2019 Mrg-Cap Symposium, Jonathan Tyrrell

Middle Rio Grande Conservation Action Plan Symposium (2019)

No abstract provided.

Long-Term Impacts On Rio Grande Fish Foodweb Structure And Function, Tom Turner

Middle Rio Grande Conservation Action Plan Symposium (2019)

No abstract provided.

Riparian And Wetland Vegetation Communities, Ondrea Hummel

Middle Rio Grande Conservation Action Plan Symposium (2019)

No abstract provided.

Middle Rio Grande Conservation Action Plan - The Dynamic Patch Mosaic Ecosystem Framework, Esteban Muldavin, Elizabeth Milford, Lee Grunau, Renee Rondeau, Yasmeen Najmi

Middle Rio Grande Conservation Action Plan Symposium (2019)

No abstract provided.

The Copy Number Variation Landscape Of Congenital Anomalies Of The Kidney And Urinary Tract, Miguel Verbitsky, Rik Westland, Alejandra Perez, Krzysztof Kiryluk, Qingxue Liu, Priya Krithivasan, Adele Mitrotti, David A Fasel, Ekaterina Batourina, Matthew G. Sampson, Monica Bodria, Max Werth, Charlly Kao, Jeremiah Martino, Valentina P Capone, Asaf Vivante, Shirlee Shril, Byum Hee Kil, Maddalena Marasà, Jun Y. Zhang, Young-Ji Na, Tze Y. Lim, Dina Ahram, Patricia L. Weng, Erin L. Heinzen, Alba Carrea, Giorgio Piaggio, Loreto Gesualdo, Valeria Manca, Giuseppe Masnata, Maddalena Gigante, Daniele Cusi, Claudia Izzi, Francesco Scolari, Joanna A E Van Wijk, Marijan Saraga, Domenico Santoro, Giovanni Conti, Pasquale Zamboli, Hope White, Dorota Drozdz, Katarzyna Zachwieja, Monika Miklaszewska, Marcin Tkaczyk, Daria Tomczyk, Anna Krakowska, Przemyslaw Sikora, Tomasz Jarmoliński, Maria K. Borszewska-Kornacka, Robert Pawluch, Maria Szczepanska, Piotr Adamczyk, Malgorzata Mizerska-Wasiak, Grazyna Krzemien, Agnieszka Szmigielska, Marcin Zaniew, Mark G. Dobson, John M. Darlow, Prem Puri, David E. Barton, Susan L. Furth, Bradley A. Warady, Zoran Gucev, Vladimir J. Lozanovski, Velibor Tasic, Isabella Pisani, Landino Allegri, Lida M. Rodas, Josep M. Campistol, Cécile Jeanpierre, Shumyle Alam, Pasquale Casale, Craig S. Wong, Fangming Lin, Débora M. Miranda, Eduardo A. Oliveira, Ana Cristina Simões-E-Silva, Jonathan M. Barasch, Brynn Levy, Nan Wu, Friedhelm Hildebrandt, Gian Marco Ghiggeri, Anna Latos-Bielenska, Anna Materna-Kiryluk, Feng Zhang, Hakon Hakonarson, Virginia E. Papaioannou, Cathy L. Mendelsohn, Ali G. Gharavi, Simone Sanna-Cherchi

Pediatrics Research and Scholarship

Congenital anomalies of the kidney and urinary tract (CAKUT) are a major cause of pediatric kidney failure. We performed a genome-wide analysis of copy number variants (CNVs) in 2,824 cases and 21,498 controls. Affected individuals carried a significant burden of rare exonic (that is, affecting coding regions) CNVs and were enriched for known genomic disorders (GD). Kidney anomaly (KA) cases were most enriched for exonic CNVs, encompassing GD-CNVs and novel deletions; obstructive uropathy (OU) had a lower CNV burden and an intermediate prevalence of GD-CNVs; and vesicoureteral reflux (VUR) had the fewest GD-CNVs but was enriched for novel exonic CNVs, …

Swmpp Appendices 2019, Sandia National Laboratories/Nm

Municipal Separate Storm Sewer System (MS4) Permit

No abstract provided.

Out Of Africa: The Ecological Context And Constraints On Early Homo Migration, Kathryn Gwen Sokolowski

2020 Award Winners

No abstract provided.

Supporting Data For Allometric Relationships For Quercus Gambelii (Gambel Oak) And Robinia Neomexicana (New Mexico Locust) For Field And Remote Sensing Biomass Retrieval In Post-Disturbance Landscapes, Dan J. Krofcheck, Matthew D. Hurteau, Marcy E. Litvak

Biology Datasets

----File description----

allometry_data.csv: All of the field measurment data that went into calculating the area and volume to biomass regressions

allometry_repo.slides.html: Reveal.js slides for the workflow surrounding the allometry manuscript, including figure generation

jemez_allometry_LA.csv: All of the associated leaf weight and leaf scan data used to calculate species specific leaf area

JemezAllometry_Workbook.xlsx: Microsoft Excel workbook containing an example application of the allometric equations

University Of New Mexico Health Sciences Center Discovery Research Annual Report 2019, Michael Haederle, Jana Fothergill, Emily Monteiro Morelli, Yamhilette Licon Muñoz, Nicole Maphis, Seth Fuller, Jett Loe, Allan Stone

Research Annual Reports

No abstract provided.

Environmental Ramifications Of The Textile Industry, Sarah Ann K. Polsin

2019 Award Winners

No abstract provided.

The Endocytotic Fate Of A Mesoporous Silica Nanoparticle Supported Lipid Bylayer Crispr Delivery Vehicle, Angelea Maestas-Olguin

2019 Award Winners

No abstract provided.

Ms4 Swmpp 2019, Sandia National Laboratories/Nm

Municipal Separate Storm Sewer System (MS4) Permit

No abstract provided.

Dombi Interval Valued Neutrosophic Graph And Its Role In Traffic Control Management, D. Nagarajan, M. Lathamaheswari, S. Broumi, J. Kavikumar

Neutrosophic Sets and Systems

No abstract provided.

Decoupling The Effects Of The Amyloid Precursor Protein From Amyloid-Β Plaques On Axonal Transport Dynamics In The Living Brain, Christopher S. Medina, Taylor W. Uselman, Daniel R. Barto, Frances Cháves, Russell E. Jacobs, Elaine L. Bearer

Pathology Research and Scholarship

Amyloid precursor protein (APP) is the precursor to Aβ plaques. The cytoplasmic domain of APP mediates attachment of vesicles to molecular motors for axonal transport. In APP-KO mice, transport of Mn2+ is decreased. In old transgenic mice expressing mutated human (APPSwInd) linked to Familial Alzheimer's Disease, with both expression of APPSwInd and plaques, the rate and destination of Mn2+ axonal transport is altered, as detected by time-lapse manganese-enhanced magnetic resonance imaging (MEMRI) of the brain in living mice. To determine the relative contribution of expression of APPSwInd versus plaque on transport dynamics, we developed a Tet-off system to decouple expression …

Fluctuating Age Distributions And Sex Ratio Tracking In A Protandrous Shrimp, Eric L. Charnov, Scott Groth

Biology Faculty & Staff Publications

ESS theory for plastic sex ratio is tested in a long term (39 yr) data set for a Pandalid Shrimp.

Preservation Protocols For Maintaining Species Stability Of Arsenic, Chromium, And Selenium In Water Samples, Contessa Lowery

Water Resources Professional Project Reports

Water quality has become an increasing concern in recent years. The environmental challenges surrounding water quality include the presence of dissolved metals and their potential impact on human health and the environment. The challenge is exacerbated because many important metals have multiple oxidation states, which affect the health and environmental behavior of the metal. Many metals are known carcinogens and increased anthropogenic effects have inexorably made metals’ accumulation an imposing threat. Analytical instrumentation has advanced in many areas, making it now possible to measure very low concentrations of multiple elements in water. Current interest is determining the chemical speciation of …

Nidus Idearum. Scilogs, Iv: Vinculum Vinculorum, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

Welcome into my scientific lab! My lab[oratory] is a virtual facility with non-controlled conditions in which I mostly perform scientific meditation and chats: a nest of ideas (nidus idearum, in Latin). I called the jottings herein scilogs (truncations of the words scientific, and gr. Λόγος – appealing rather to its original meanings "ground", "opinion", "expectation"), combining the welly of both science and informal (via internet) talks (in English, French, and Romanian). * In this fourth book of scilogs collected from my nest of ideas, one may find new and old questions and solutions, referring mostly to topics on NEUTROSOPHY – …