Digital Commons Network^™

Nanoscale Assembly Of Dectin-1 And Its Glucan Ligand In Immunocyte Membranes And Pathogen Cell Walls, Akram Etemadi Amin

Physics & Astronomy ETDs

Candida spp. pathogens continue to be a significant health care burden with high mortality and exceeding enormous healthcare costs. Candida infection range varies from dermatological infection to more severe bloodstream infection in debilitated patients. Due to this, research dedicated to understanding biophysical interactions between Candida species and the host’s immune cells is essential. The C-type lectin’s (CtLs) are known to bind to Candida cell walls and play a crucial role in downstream immune signaling. It is known that β-glucans, the highly immunogenic polysaccharide in Candida’s cell wall, are mostly masked underneath a layer of mannosylated proteins. The amount of …

Decompositions Of Total Causal Effect: A Natural Counterfactual Framework Assessing Mediation And Interaction, Xin Gao

Mathematics & Statistics ETDs

In this work, we developed ten-way decompositions of the total causal effect on continuous outcomes in the presence of two mediators that have mediation and interaction components. We considered a natural counterfactual interaction effect framework that facilitates the decomposition of the total casual effects of the exposure on the outcome attributable to the effects of mediators and their interaction effects with the exposure. We discussed the identification assumptions and provide empirical formulas for estimating the components of the ten-way decompositions. We also developed multiplicative total causal effect decompositions based on risk ratios for binary outcomes, hazard ratios and logarithm survival …

Weedy Relations: Narratives Of Invasion And Intimacy With Tamarisk In The Chihuahuan Desert, Shannon S. Pepper

Geography ETDs

Tamarix spp., also known as salt cedar or tamarisk, is a shrub that has garnered a notorious reputation in North America as an invasive plant, with widespread policy and research advocating for its eradication in the Southwest U.S. and Northern Mexico. This study examines both governmental conservation documents and news articles to investigate narrative trends on tamarisk in the Southwestern U.S. and Northern Mexico as a contiguous region (the Chihuahuan Desert), expanding on current research to include transborder effects on the perception and management of introduced species. This paper asks: In the last 25 years, how has the movement, …

Regulation Of H2s Production And Signaling Within Vascular Endothelium, Perenkita J. Mendiola

Biomedical Sciences ETDs

Hydrogen sulfide (H2S) is a vasodilator primarily produced by cysthathionine

gamma-lyase (CSE) within the vasculature. Previous studies suggest there are

differences in CSE expression and the contribution of H2S to vasodilation in

different sized arteries. This led us to postulate that there are also regional

differences of regulators of H2S-mediated vasodilatory pathways.

This study examined the role of endothelial cell plasma membrane (EC

PM) cholesterol in regulating H2S-induced vasodilation and the role of

intracellular calcium [Ca2+]i in regulating CSE activity in vascular EC. We

hypothesized that CSE activation in EC by receptor-dependent second

messenger signaling enhances H2S production and subsequent …

Pt-Containing Conjugated Polymers And Small Molecules For Bhj Photovoltaic Devices, Yunjeong Kwon

Chemistry and Chemical Biology ETDs

The current state of organic photovoltaic (OPV) devices involve series of small molecular or polymeric systems that can absorb light from the solar spectrum in concert with another material that acts as an acceptor material. Together these materials serve to generate and split bound excitation species then transport the separate charges to their respected electrode. Several limitations have restricted the widescale use of these materials. Since these devices have their genesis in organic materials the OPV devices inherit short exitonic lifetimes, narrow absorption window and a lack of precise control over the morphology. To overcome these limitations, additional molecular engineering …

Interaction Of A Shock Wave With A Particle Curtain, Daniel M. Freelong

Mechanical Engineering ETDs

This thesis presents an experimental study of the interaction of a normal shock wave with a sparse curtain of particles. Soda lime particles with a nominal diameter of 40 micrometers are used to form the curtain. A high speed camera captured several segments of the particle curtain flow from the front view, including the early formation stages. The frames from the video segments were then extracted into individual sequential images. Properties were found using the images such as the velocity fields, time evolution of multiphase Atwood number, and perturbation growth. Volume fractions were derived from mass discharge measurements and particle …

Single-Crystal Elasticity Of Tremolite At High-Pressure Conditions And Its Implication For The Mid-Lithospheric Discontinuity, Soisiri Charin

Earth and Planetary Sciences ETDs

Tremolite is the calcium magnesium amphibole that widely occurs in igneous and metamorphic rocks of the crustal and upper mantle lithosphere, especially in the greenschist facies to amphibolite facies of ultramafic assemblages. The stability field of amphibole reaches 3-4 GPa and 1100-1200°C depending on water content and cation substitutions giving rise to amphibole to occur in highly variable compositions. This P-T condition, corresponding to the depth about 80-120 km, coincides with the depth range that a negative velocity gradient usually found within most stable cratonic lithospheres. This depth range is seismically called Mid-lithosphere discontinuity (MLD). The geologic processes that might …

Lysmd3: A Mammalian Pattern Recognition Receptor For Chitin, Xin He, Brad A. Howard, Yang Liu, Aaron K. Neumann, Liwu Li, Nidhi Menon, Tiffany Roach, Shiv D. Kale, David C. Samuels, Hongyan Li, Trenton Kite, Hirohito Kita, Tony Y. Hu, Mengyao Luo, Caroline N. Jones, Uju Joy Okaa, Diane L. Squillace, Bruce S. Klein, Christopher B. Lawrence

Pathology Research and Scholarship

Chitin, a major component of fungal cell walls, has been associated with allergic disorders such as asthma. However, it is unclear how mammals recognize chitin and the principal receptor(s) on epithelial cells that sense chitin remain to be determined. In this study, we show that LYSMD3 is expressed on the surface of human airway epithelial cells and demonstrate that LYSMD3 is able to bind chitin, as well as β-glucan, on the cell walls of fungi. Knockdown or knockout of LYSMD3 also sharply blunts the production of inflammatory cytokines by epithelial cells in response to chitin and fungal spores. Competitive inhibition …

Mud Binds Mitotic Kinesins Non-Claret Disjunctional And Pavarotti In D. Melanogaster, Vincent Cutillas

Biology ETDs

The cytoskeleton is crucial to maintaining an even distribution of chromosomes and subsequently to divide the cell during every cell cycle. During mitosis, spindle structure and movement dictates how chromosomes will be separated and act as the sole mechanism for even distribution of these chromosomes. The cytoskeleton also remains a major cellular component during cytokinesis when the cell must cleave the membrane in order to form two resulting daughter cells. Both processes require an extensive use of the immobile structures of the cytoskeleton, such as microtubules (MTs), intermediate filaments, and microfilaments, but also the mobile units, which are the motor …

Immodest Immortality: Emperor Maximilian I'S Artistic Program And The Ambraser Heldenbuch, 1504-1519, Jessica Cochran

History ETDs

Maximilian I (r. 1493-1519) utilized various forms of artistic and literary media throughout his reign to control his public image after his death. This thesis focuses on a manuscript project that has historically received little scholarly attention. The Ambraser Heldenbuch, produced between 1504 and 1517, preserves German heroic epics, many of which would otherwise be lost today. The manuscript has been highly valued for its literary and linguistic significance, but this thesis argues that the entire project sheds light on Maximilian’s plan to immortalize not only his own reputation, but also that of his family. This thesis focuses on …

Sisters Supporting Sisters: Photovoice & Diabetes Discourse Among Church-Based Women In New Mexico, Nina Mock Cooper

Communication ETDs

Within the expansive literature on diabetes in other disciplines, the communication lens focuses on the biomedical perspective and emphasizes doctor-patient and patient-provider relations. While there are limited studies that focus on the psychosocial aspect of diabetes morbidity, there is a gap in the existing literature across disciplines on communication about diabetes using both qualitative and participatory methods that are church-based. Because diabetes disproportionately and adversely impacts communities of color that report high levels of religious influence, there is an dire need for more effective interventions to ameliorate this chronic illness that causes high levels of morbidity and mortality.

The Sisters …

Re/ Constructing Race And Racism Among Unionized Mexican Immigrants Through Vernacular Discourse, Jocelyn Gomez

Communication ETDs

This study explores the vernacular discourse of unionized Mexican immigrants living and working in Orange County in California. Given the current political climate and the historical roots of the construction of "race" in the United States, I explore how the current sociopolitical conditions of organized Latina/o affect their understanding of race and their experiences with racism. It is also important to address the everyday racism the Latina/o community faces that continue to marginalize them. This study focuses on the vernacular discourses on race and racism of organized working-class Latinas/os who are members of labor unions. Through intentional conversations about racial …

Disability Injustice: A Latino’S Creative Autoethnographic Testimonio On The Organizational Culture Of Higher Education, Leonel A. Diaz Jr.

Organization, Information and Learning Sciences ETDs

Using creative autoethnographic testimonio (CAT), a story is told about the injustices within the learning environment and work environment of higher education toward a person with disabilities: sleep apnea, learning disabilities, negative mental health. The author explores the health difficulties of addressing sleep deprivation while attending graduate school and working full-time as a professional. With sleep apnea impacting his health, his mental health declines. As his health declines, there is an increase in discrimination, hostility, oppression, bullying, and toxic masculinity. Initially, the medical system dismisses his declining health and refuses to look further into it. Once he receives medical care …

Disrupting The (Post) Neoliberal Order In Latin America Through The Representation Of Fictional Corporate Office Narratives In Argentina And Mexico (2007-2010), Juliana Todescan

Spanish and Portuguese ETDs

Due to the expansion of the neoliberal and global order in Latin America in the 1990s, national states and citizens are subjected to the free market interests regulated and managed by for profit corporations and the financial industry. Considering this a critical change in the social organization of Latin America, I compare narratives from Argentina and Mexico that imagine cosmopolitan cities being colonized by the corporate logic of profit. My analysis focuses on the representation of low level office workers in Antonio Ortuño’s novel Recursos humanos (2007), Guillermo Saccomanno’s novel El oficinista (2010), and Aníbal Jarkowski’s El trabajo (2007), and …

Dynamic Hvac Energy Management Using Commercial Building Occupancy Metrics & Neural Networks, Krishna Chaitanya Jagadeesh Simma

Civil Engineering ETDs

With the rise of technology use in buildings, it is now possible to collect data that can be used to improve building energy consumption. One factor that has significant impact on building energy consumption is occupancy. Recent studies have shown promising results in obtaining occupancy information from existing infrastructure such as WiFi router networks. However, these existing frameworks require additional investments through software upgrades, added infrastructure, computational resources, and may raise occupant privacy concerns. Additionally, with occupant thermal comfort statistics being lower than ASHAREA specified standards, a novel approach for indoor climate control is needed. To address the limitations in …

Examination Of Intuitive Eating At The Momentary Level, Jamie M. Smith

Psychology ETDs

Background: Intuitive eating involves following internal cues of hunger and satiety to guide eating choices, as opposed to responding to external signals, strong emotions, or dietary rules. This style of eating consistently has been shown to be related to better physical and psychological health indicators. This construct would be better understood if studied at the individual momentary level instead of globally or cross-sectionally. Therefore, the proposed study sought to employ ecological momentary assessment (EMA) to examine the validity of intuitive eating at the momentary level. Additionally, the acceptance and expanded acceptance models of intuitive eating and the roles of weight …

Unm Pathology Pathfinder Summer 2021, Unm Department Of Pathology

Newsletters

No abstract provided.

Hand Of The Potter, Hand Of The State: Pottery Production And Control In Tawantinsuyu, James A. Davenport

Anthropology ETDs

In empires, material culture plays an important role in creating and maintaining state power and legitimizing imperial rule. Through their form and decoration in imperial styles, these objects convey messages about state power, yet their production is often decentralized and carried out by subjects. This dissertation asks the question, how do imperial authorities organize the production of material culture? This question is addressed through a study of one category of material culture—Inka imperial pottery—from the site of Pachacamac, in Peru.

The Inka empire, called Tawantinsuyu, was a territorial empire spanning over 2 million km² in Andean South America …

New Mexican Parents’ Perspectives Regarding Public Schools’ Communication And Language Services For Their Elementary-Aged Children With Autism Spectrum Disorder During Covid-19, Susanna E. Cole

Speech and Hearing Sciences ETDs

This study explored five New Mexican parents’ perceptions of changes to the public school-based communication and language services for their children with autism spectrum disorder (ASD) during the Covid-19 pandemic and the subsequent advantages and disadvantages of these changes. The parents participated in semi-structured interviews between October 2020 and February 2021. All of the parents reported their children’s services had eventually gone completely remote, but one had secured some in-person instruction time for her child by the time of her interview. Three parents reported reduction in school-based communication and language services for which they sought to compensate through other means. …

Quick Pivots: Maintaining An Agile Approach To Outreach During An Evolving Crisis, Holly M. Surbaugh

University Libraries & Learning Sciences Faculty and Staff Publications

As the University of New Mexico responded to the coronavirus pandemic during the spring and summer of 2020, the University Libraries piloted enhanced virtual outreach initiatives, including an online event series and scaled-up social media activity. The Summer of Sci Fi (SoSF) consisted of three Zoom-facilitated programs that offered fun activities designed to engage a socially distanced campus community while highlighting various library resources. Numerous “quick pivots” were necessary to accommodate unpredictable circumstances throughout the pilot implementation. This experience has demonstrated the advantages of approaching outreach with an agile stance, particularly during a crisis.

New Diagnosis Of X-Linked Agammaglobulinemia Presenting As Multi-Focal Acute Pseudomonal Osteomyelitis And Septic Arthritis In A 16-Month Old Boy: A Case Report, Walter Dehority

Western Journal of Orthopaedics

A previously healthy 16-month-old boy presented with 5 days of fever, a limp favoring his right side, and swelling and erythema of the dorsal left foot and left great toe. Contrasted magnetic resonance imaging revealed septic arthritis of the left knee, the interphalangeal joint of the left great toe, and the left subtalar and ankle joints. He had osteomyelitis of the left talus and intraosseous abscess formation in the left calcaneus. Cultures of the blood, left knee synovial fluid, and abscess fluid all showed growth of Pseudomonas aeruginosa. He was subsequently diagnosed with X-linked agammaglobulinemia with a novel mutation in …

Reconstruction Of A Chronic Quadriceps Tendon Rupture After Multiple Failed Repair Attempts: Technique And Case Report, Lauren Edge, Elizabeth Mcleod, Om Pathak, Justin Bartley

Western Journal of Orthopaedics

Rupture of the quadriceps tendon is a relatively uncommon injury that requires prompt surgical intervention to restore the function of the extension apparatus of the knee. Early, definitive surgical intervention generally produces excellent results. In the case of delayed surgery or re-rupture, the tendon is often retracted and scarred, thus complicating subsequent repairs and resulting in poor outcomes. We describe a middle-aged man who presented 4 years after his initial quadriceps rupture, following two repair attempts that failed. Upon presentation, he was unable to perform any active extension at the knee, and he ambulated with the use of a hinged …

Utilizing The Behavioral System Model For Adolescent Depression In The School Setting, Megan Mcguiness

Theoretical Foundation in Advanced Practice Nursing

No abstract provided.

Spanish-Origin Verbal And Grammatical Borrowing In Paraguayan Guaraní, Josefina Bittar Prieto

Linguistics ETDs

Previous work on language change in contact situations has treated lexical borrowing and grammatical borrowing as discrete phenomena (Appel and Muysken 1987, Thomason 2001, Campbell 2013). Claims that lexical borrowing needs to occur before grammatical borrowing (e.g. Thomason and Kaufmann 1988) or that grammar can be borrowed without any lexicon (e.g. Aikhenvald 2002) are often mentioned in the literature. This dissertation explores the interplay between grammatical constructions (in the sense of Goldberg 2006) and lexical elements in intense contact situations. More specifically, it addresses the following research question: Are grammatical constructions borrowed independently from the elements contained in said constructions? …

Fatigue Predicts Future Reduced Social Participation, Not Reduced Physical Function Or Quality Of Life In People With Systemic Sclerosis, Susan L. Murphy, Daniel Whibley, Anna L. Kratz, Janet L L. Poole, Dinesh Khanna

Pediatrics Research and Scholarship

OBJECTIVE: Although fatigue is one of the most problematic symptoms for people with systemic sclerosis, little is known about how fatigue impacts daily life over time. Such information is important when developing fatigue management interventions. This study was conducted to examine 1) if fatigue severity predicted outcomes of worse functioning (social participation, physical function), and quality of life and 2) if level of self-efficacy moderated significant relationships between fatigue and these outcomes.

METHODS: Data were utilized from a clinical trial in which an online self-management intervention was tested (N = 267). Fatigue, social participation, and physical function were assessed by …

Private Actors, Public Records, And New Mexico’S Inspection Of Public Records Act, John Kreienkamp

New Mexico Law Review

In a series of three recent court decisions, New Mexico’s appellate courts have grappled with IPRA’s implications for private entities. In State ex rel. Toomey v. City of Truth or Consequences2 and New Mexico Foundation for Open Government v. Corizon Health, the Court of Appeals held that the records of a private contractor performing services on behalf of a public body were subject to inspection under IPRA to the extent they related to government business.

This article maintains that IPRA requests must be directed to the public body, not a private contractor, and that a private entity is not a …

Submittal Of Mixed Waste Landfill Annual Long-Term Monitoring & Maintenance Report, April 2020-March 2021 For Sandia National Laboratories/New Mexico, Epa Id Number Nm5890110518, June 2021, Sandia National Laboratories/Nm

Facilities-Units

The Department of Energy/National Nuclear Security Administration (DOE/NNSA) and Sandia National Laboratories /New Mexico (SNL/NM) personnel submitted the Mixed Waste Landfill (MWL) Annual Long-Term Monitoring and Maintenance Report for the April 2020 through March 2021 reporting period to the New Mexico Environment Department (NMED) in accordance with the requirements of Section 4.8.1 of the MWL Long-Term Monitoring and Maintenance Plan (LTMMP). The LTMMP became effective on January 8, 2014.

The MWL is a 2.6-acre Solid Waste Management Unit (SWMU 76) located in the north-central portion of SNL/NM Technical Area III that has undergone corrective action. As of March 13, 2016, …

Plant-Based Beverages In The Diets Of Infants And Young Children, Lisa M. Bodnar, Elizabeth Y. Jimenez, Susan S. Baker

Pediatrics Research and Scholarship

No abstract provided.

New Mexico Domestic Violence Needs Assessment, Theresa H. Cruz, William F. Athas, Ivy Vitanzos Cervantes, Alexis Kaminsky, Yvonnie C. Vitanzos, Mary R. Bartlett, Camille R. Velarde

Reports & Documents

No abstract provided.

Satisfaction And Willingness To Recommend: Patient Experience In A Southwestern Healthcare Organization, Judy A. Sanchez

Nursing ETDs

This descriptive study examined perceptions of hospital care in a minority majority state within adult Hispanic white, American Indian, and non-Hispanic white patients using the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey. This secondary analysis of de-identified 2016-2018 data involved 10,181 patients discharged from two urban and five rural hospitals. Demographic variables included: race/ethnicity, preferred language, and hospital location. HCAHPS variables included: overall satisfaction, willingness to recommend, nurse communication, physician communication, responsiveness of hospital staff, pain management, medication communication, cleanliness and quietness, discharge information, and transition of care. Chi-square and loglinear analyses demonstrated that Hispanic whites, and …