Digital Commons Network^™

An Analysis Of The Results Of Court Of Arbitration For Sport Doping Awards Involving Athletes Between 1994 And 2008., Genevieve F.E. Birren Esq.

Health, Exercise, and Sports Sciences ETDs

The purpose of this study was to create a database of Court of Arbitration for Sport (CAS) awards coded for a variety of factors and then examine those factors to determine whether they had any relationship to the outcome of the CAS awards involving athletes and doping. The initial pool of awards was downloaded from the CAS website and then each award was read and coded for certain information, specifically case name, year, date decided, division, sport, party role, party name, issue, rule applied, sex, decision, and arbitrators deciding. Once this coding was complete the result was a database of …

Developing More Specific Mirna Biogenesis Inhibitors To Get Effective Regulation Of Mirnas, Umesh Bhattarai

Chemistry and Chemical Biology ETDs

MicroRNAs (miRNAs) are short (~ 22 nucleotides long) noncoding RNAs that regulate gene expression post-transcriptionally. They control the expression of various genes that are crucial for cellular function, development and human diseases. Tools to regulate the level and function of miRNAs facilitate the studies of their functions and have therapeutic applications. In my thesis, I developed a newly customizable miRNA biogenesis inhibitor to regulate miRNAs.

Antisense oligonucleotides (ASOs) have been used to regulate miRNA through controlling their production or function. Although commonly used due to the fact that they are easy to design, several limitations exist for ASOs including serious …

Evaluating The Utility Of Object-Based Image Analysis For Ecological Monitoring Of Pinon-Juniper Mortality, Zachary C. Taraschi

Geography ETDs

Forested ecosystems in the American Southwest are experiencing change at an unprecedented rate, largely due to mortality events triggered by increased temperatures, drought, and insect infestations. Large-scale changes in the distributions of these ecosystems can potentially alter regional-scale carbon, water and energy dynamics. One biome in particular that has experienced increased mortality and altered forest composition over the past 30 years are Piñon-Juniper woodlands (Pinus edulis, Juniperus spp.) in the American Southwest. New fields of study, in particular, Remote Sensing, are applying and adapting traditional methods for ecological monitoring of these woodlands. Remote sensing offers the potential to synoptically …

Autophagy Is Stimulated By Acute High Intensity Interval Exercise In Human Skeletal Muscle And Electrical Pulse Stimulation In C2c12 Myotubes In Vitro, Kurt A. Escobar

Health, Exercise, and Sports Sciences ETDs

Purpose: 1) To compare the effects of an acute bout of HIIT exercise (treadmill running) on autophagy to MICT exercise in human skeletal muscle 3 hours post exercise, and 2) to test an in vitro model of muscle contraction-induced autophagy using electrical pulse stimulation in C2C12 myotubes. Methods: Study 1: Ten recreationally active males and females completed a bout of high intensity interval training (HIIT) exercise and moderate intensity continuous exercise (MICT) exercise in a fasted state. Muscle biopsies from the vastus lateralis were taken pre and 3 hours post-exercise. Muscle tissue was analyzed for protein expression of markers of …

Effects Of Exposure To Violence On Health In Iraq Between 2006-2007, Fatemeh Shahandeh

Economics ETDs

Iraq has experienced protracted years of war in last two decades. These prolonged years of war in Iraq manifested conflict and violence, degeneration of economic conditions and a serious breakdown of public health services. Deaths, injury and acts of violence such as kidnapping, threat and witnessing heavy casualties are only a few examples of events that Iraqi people experienced during war times. Conflict can result in lasting and profound consequences for the health of the Iraq population. The burden of the communicable, non-communicable disease and mental illnesses in war zone areas is rising rapidly and becoming a major challenge to …

08-13-2018 Notice Of Hsc Committee Mtg, Patrice Martin

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Advantages Of Percutaneous Endoscopic Gastrostomy Tube Placement In Patients With Head And Neck Cancer Who Receive Radiation As Part Of Their Treatment, Nevin Thul

Speech and Hearing Sciences ETDs

The use of percutaneous endoscopic gastrostomy tubes as an intervention strategy in head and neck cancer was investigated in this retrospective chart review. Twenty-five veterans met the inclusion criteria and were categorized into two groups – use of prophylactic percutaneous endoscopic gastrostomy and absence of percutaneous endoscopic gastrostomy tube placement. Medical charts were reviewed and data extracted included weight, swallow function, swallow exercise compliance, and physical and social quality of life for 2 years post-treatment. Month-to-month data were compared across the two groups with respect to weight, swallow function, swallow exercise compliance, and physical and social quality of life scores. …

Ethnic And Racial Group Differences In Attitudes Towards Undocumented Latino Immigrants, Juan M. Pena

Psychology ETDs

Tensions towards Latino immigrants in the United States have been a growing concern. As the largest ethnic/racial and immigrant group, Latinos/Hispanics often experience discrimination from majority groups. Perceived discrimination has been linked to worse mental and health outcomes among ethnic minority groups. Measures of implicit and explicit attitudes have been used to identify positive and negative attitudes towards Latinos. Intercultural sensitivity, the ability to understand and appreciate different cultures, is theorized to be linked to implicit and explicit attitudes towards undocumented Latino immigrants. Two-hundred eighty-eight college students, 18 years of age or older (M = 21, SD = 5) completed …

Implicit And Explicit Attitudes Toward Physical Appearance Among Recurrent And Non-Binge Eating College Women, Mindy L. Mcentee

Psychology ETDs

Research has found that among individuals who binge eat, overvaluation of body weight/shape and internalization of a thin ideal are associated with higher levels of distress and functional impairment. These findings suggest implicit attitudes and beliefs may play an important role in understanding the complex relations between one’s cognitions and subsequent eating behavior; however, much of the research on binge eating has relied on explicit self-report measures which may not accurately reflect the way individuals automatically process body weight/shape information or the meaning one has associated with these characteristics. The present study sought to address this gap in the literature …

Neurobehavioral Signatures In Children-Victim Of Bullying, Isabel Solis

Psychology ETDs

Experiencing bullying victimization can lead to detrimental damage to a child’s life potential, reduced long-term contributions to society, and in severe cases, to suicide or desperate acts of defensive aggression, such as school shootings. The current study aimed to examine risk factors that may increase the vulnerability of a child to become a target of bullying victimization and the related consequences of victimization, using rigorous neuropsychological and EEG measures. The end-goal is to translate these findings into a program of preventive intervention increasing the child’s resilience and improving social culture among youth in the academic environment. We propose a two-component …

Women's Response Performance In Sexually Risky Situations: Associations With Sexual Victimization History, Alcohol Use, Psychopathology, And Sexual Attitudes, Kristen N. Vitek

Psychology ETDs

This study evaluated the effects of sexual victimization history, alcohol use, psychopathology, and sexual attitudes on the effectiveness of women’s response performance in hypothetical social situations depicting risk for sexual victimization. Two hundred and fifty undergraduate women first listened to audiotaped descriptions of the hypothetical social situations. They then were given a response to each situation deemed in prior work by experts in the sexual victimization field to be effective at reducing victimization risk and asked to provide each response verbally while they were being videotaped. Participants then completed measures assessing prior victimization history, alcohol use, psychopathology, and sexual attitudes. …

Niemann-Pick C1, Its Connection To Obesity, And Its Impact On Human Evolution, Joseph Joshua Castillo

Biomedical Sciences ETDs

Niemann-Pick type-C disease is a rare autosomal recessive neurodegenerative disease that classically presents in the first decade, leading to ataxia, vertical-gaze palsy, loss of communication skills, epileptic seizures, and eventually death. The stark reality about NPC disease underlines the important role the NPC1 protein plays in whole-body lipid homeostasis. It is no surprise, then, that the NPC1 gene has been associated with other diseases as well, such as obesity, diabetes, and Ebola virus infection. In this manuscript, a connection will be made that intertwines genetics, biochemical and molecular mechanisms, physiology, and evolutionary pressures, and will explain how a gene, discovered …

Characterizing Patterns In E. Coli Levels In Rio Grande River Water And Riverbed Sediments Near Albuquerque, Nm, James Fluke

Civil Engineering ETDs

In this work I examined how Fecal indicator Bacteria (FIB) behave in a large environmental system (Rio Grande near Albuquerque, ~60 km distance). I addressed the questions: How do FIB levels in river water and riverbed sediments of this reach change with distance along the river and throughout one year?

I conducted year-round river water and sediment sampling for concentration of E. coli bacteria, a persistent contaminant in the area. I found that over the year, E. coli loading in river water increased along the 60 km reach and E. coli in the sediments mainly increased near the Albuquerque urban …

Water And Healthcare Access Disparities: Impacts On Health, Wealth And Education., Justin Whetten

Economics ETDs

Rural communities in the United States and developing countries face a common problem of access. Lack of clean water or medical specialists can be solved by current technology, but there is a lack of resources and understanding of the problems. Rural communities in developing countries have a lack of access to clean water. Expansion of current water infrastructure and sanitation facilities could be done, but these are large costly projects. The lack of clean water, however, has dire negative effects on child mortality, household morbidity and overall household earning potential. In the United States, rural communities face a similar problem …

Analyzing The Medical Definition Of Death In Criminal Homicide Prosecution, Mariah Wood

Nursing ETDs

I investigated the use of the medical definition of human death in the criminal justice system and the impact of this definition on the prosecution of criminal homicide. The units of design for this research were two violent crimes cases investigated by the Homicide Unit of the Albuquerque Police Department. Data was collected from officer interviews, case files, Office of the Medical Investigator reports, media and social media.

I identified the themes of pursuit of justice, frustration, and family from the collected data. Key findings include that the medical definition of human death causes confusion and delay in the criminal …

Metal Reactivity In Laboratory Burned Wood From A Watershed Affected By Wildfires, Asifur Rahman

Civil Engineering ETDs

Massive amounts of wood ash are deposited into nearby streams as a result of runoff from storm events after increasing frequency of wildfire events that negatively affect water quality. Ash and debris from burned vegetation can alter the pH, turbidity and dissolved oxygen (DO) in water and can release heavy metals, organic matter, and nutrients. We investigated interfacial processes affecting metal mobility in wood ash burned under laboratory-controlled conditions using aqueous chemistry, microscopy and spectroscopy analyses. Wood was collected from the Valles Caldera National Preserve in New Mexico which has experienced two wildfires since 2011 that have caused devastating effects. …

Pre-Boomer Students On Campus: An Exploratory Study Of How Students Born Before 1946 Experience The Youth-Oriented Campus Culture At Unm, Elinor Sue Coates Phd

Organization, Information and Learning Sciences ETDs

Older learners have been studied thoroughly, except for those born before 1946, preceding the post-war "population bulge" (Carlson, 2008; Laditka, Fischer, Laditka, & Segal, 2004; Verstynen, 2011). Most such studies define "older" as over 25 or over 40, and fail to separate the subject group from those who came later. Defining a group by numerical age is problematic because it changes every year and soon omits the group's defining life experiences (Pilcher, 1994), which for this group include the Great Depression, World War II, the polio epidemic, and life before television. To address that gap this critical ethnography explored the …

Cuba Is Now Home To An Official Continental Divide National Scenic Trail Stamp, University Of New Mexico Prevention Research Center

Events

Cuba is now home to an official Continental Divide National Scenic Trail stamp, one in a series of nationwide collectible cancellation stamps.

Reasons To Ramble, University Of New Mexico Prevention Research Center

Events

The following story was written by Whitney Cappellucci, a current med student at The University of New Mexico originally from Raton, a small city in northeastern New Mexico.

Effect Of Undergraduate Research Programs On Retention Of Hispanic Students, Kiyoko N. Simmons

Organization, Information and Learning Sciences ETDs

The Hispanic population in the United States has been increasing, which is affecting the number of Hispanic student population in the higher education. In spite of the rapid increase of Hispanic student population, little empirical research has been conducted on the Hispanic student’s college success. This study investigated the effect of participating in holistic undergraduate research programs on retention outcome of Hispanic students at The University of New Mexico. UNM is a public Hispanic-Serving Institution where 47.3 percent of undergraduate students are Hispanic in 2016.

The Vincent Tinto’s theory of student departure and the five critical factors of retention developed …

Religiosity/Spirituality And Cancer Risk Assessment For Hereditary Breast And Ovarian Cancer: Latina And Non-Latina Women In New Mexico, Belinda Vicuna Tellez

Psychology ETDs

Introduction: Although cancer risk assessment for high-risk individuals and families can offer life-saving information and options for cancer risk management, Latinas have historically underutilized cancer prevention services. Much needed is a better understanding of what encourages and discourages engagement in cancer risk assessment services among Latino populations. Religiosity/spirituality is potentially relevant to such engagement given religion has often been a central coping resource for Latina cancer survivors.

Aim: This study explored the potential impact of religiosity/spirituality and psychological processes on how Latinas and non-Latinas approach decisions regarding preventative health behaviors.

Methods: As a small subset of a larger research project, …

Laterality In The Power Five And Group Of Five Conferences In Women's College Softball, Jon C. Nachtigal

Health, Exercise, and Sports Sciences ETDs

Females in sport are under-represented in data and analysis when compared to their male counterparts. This disparity also applies to women’s softball in comparison to men’s baseball. To help fill this gap, this study evaluated the extent and impact of laterality in women’s college softball’s Power Five and Group of Five conferences from 2015-2017.

This study focused on the extent of a left-sided lateral preference in women’s college softball, possible interactions between throwing hand and batting preference, to what extent the platoon effect exists in the sport, and the extent of positional bias in the sport. As one of the …

Dental Hygienists' Knowledge Of Medical Marijuana: A Survey, Lizbeth Hinojos

Dental Hygiene ETDs

Cannabis consumption is at an all-time high in the United States. Due to its fast growth in the medical industry and the lack of FDA approval, research is very limited. Dental hygienists’ will likely encounter a patient under the influence of this substance in the dental office. To provide the best quality of care, the dental hygienist must be aware of the oral implications, side effects and necessary modifications to treatment. Therefore, dental hygiene providers must be knowledgeable on medical marijuana to have discussions with patients when needed. Due to scarce research on the topic it makes it difficult to …

A Multi-Level Study Of Clearance: The Role Of Gender, Jenna Dole

Sociology ETDs

Objective. To examine the role that gender plays in the clearance of a reported criminal incident, and whether it varies across places. Methods. Using multi-level logistic regressions, data from the 2014 National Incident-Based Reporting System (NIBRS), 2010 Census data, 2013 Law Enforcement Management Statistics, and the 2010 Municipal Yearbook are used to examine the effects of a victim’s sex on crime clearance. Results. Women are initially advantaged in clearance before controlling for any evidentiary factors. However, most of the relationship is explained away when controlling for the relationship between the victim and the offender. Women are more likely to be …

Deposition Of Fr. John Daniel, Hall & Monagle, Llc

Other Depositions

No abstract provided.

American Indian Student Motivation At A Tribal College, Rebecca L. Izzo

Individual, Family, and Community Education ETDs

The purpose of this study was to explore relationships between motivational characteristics of American Indian college students attending a tribal college. The Inventory of School Motivation (ISM) was utilized to identify motivational constructs. The literature in general continues to portray American Indian students as the lowest academically achieving subgroup as well as having a lack of persistence and high dropout rate in higher education. This study identified areas that support motivation to attend college, which then can be shared with the tribal college to develop programs and innovations to recruit and sustain American Indian students in education, as well as …

The Effect Of Breathy And Strained Vocal Quality On Vowel Perception, Sarah Nieman

Speech and Hearing Sciences ETDs

INTRODUCTION: Research into speech intelligibility in dysarthria historically focuses on articulation deficits. However, voice quality deficits associated with motor speech disorders may also impact speech perception. This study investigates how breathy and strained vocal quality affects vowel identification and ratings of vowel goodness.

METHODS: A healthy speaker recorded vowels with normal, simulated breathy and simulated strained voice quality. Acoustic, physiologic, and perceptual measures confirmed the presence of the desired voice deficits. 16 volunteer listeners participated in three perceptual tasks: vowel identification, vowel goodness ratings, and voice quality ratings.

RESULTS: In the voice quality rating task, listeners detected voice quality deficits …

Psychological Factors And The Relation Between Neighborhood Conditions And Latino Health: A Mixed Methods Study, Patricia Rodriguez Espinosa

Psychology ETDs

Latinos, the largest racial/ethnic minority group in the US, face multiple health inequities including higher rates morbidity and mortality. Despite the importance of context and the wide range of stressors faced by this population, the majority of the literature on Latino and immigrant health concentrates on issues related to cultural adaptation processes. Using a socialdeterminants of health framework, the present convergent mixed methods study investigated the relation between neighborhood conditions and Latino health with a psychological lens. A total of 361 Latino residents of Bernalillo County, the largest county in Albuquerque, New Mexico, were recruited to complete a series of …

Regulating Mirna Biogenesis By Small Molecules, Hao Yan

Chemistry and Chemical Biology ETDs

MiRNAs are key cellular regulators and their dysregulation is associated with many human diseases. The development of miRNA inhibitors has significant implications for the therapy of diseases associated with aberrant miRNA expression. It also provides chemical tools for studying miRNA function. This dissertation focuses on the development of small-molecule based miRNA inhibitors targeting miRNA biogenesis.

The dissertation consists of four chapters. In Chapter 1, the biogenesis of miRNA was first introduced, followed by the explanation of miRNA function in health and disease. Then the approaches used for regulating miRNA were reviewed. Finally, the difficulties with miRNA regulation were summarized.

One …

Developing Droplet Based 3d Cell Culture Methods To Enable Investigations Of The Chemical Tumor Microenvironment, Jacqueline Alexandria De Lora

Biomedical Sciences ETDs

Adaptation of cancer cells to changes in the biochemical microenvironment in an expanding tumor mass is a crucial aspect of malignant progression, tumor metabolism, and drug efficacy. In vitro, it is challenging to mimic the evolution of biochemical gradients and the cellular heterogeneity that characterizes cancer tissues found in vivo. It is well accepted that more realistic and controllable in vitro 3D model systems are required to improve the overall cancer research paradigm and thus improve on the translation of results, but multidisciplinary approaches are needed for these advances. This work develops such approaches and demonstrates that new droplet-based cell-encapsulation …