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Full-Text Articles in Entire DC Network
“Medication Is Only 10% Of Recovery”: A Mixed-Method Analysis Of Facilitators And Barriers To The Equitable Implementation Of Medications For Opioid Use Disorder Treatment, Alexandra Hernandez-Vallant
“Medication Is Only 10% Of Recovery”: A Mixed-Method Analysis Of Facilitators And Barriers To The Equitable Implementation Of Medications For Opioid Use Disorder Treatment, Alexandra Hernandez-Vallant
Psychology ETDs
Medications for opioid use disorder (MOUD), the gold standard treatment for OUD, are underutilized. Yet, research on MOUD clinical encounters is limited. Attention to social determinants of health (SDOH) can help improve engagement and retention in MOUD treatment. This dissertation project describes development of a clinical vignette-based survey using a two phase exploratory sequential design to examine the extent to which SDOH influence clinical decision-making among MOUD providers. Study 1 included interviews with 23 providers to learn their perspectives on facilitators/barriers to MOUD treatment and the clinical and social determinants most influential to their clinical decision-making. Study 2 involved development …
Influences Of The Western Press On News Framing Of Global Events In Developing Countries: Examining Covid-19 And Climate Coverage In A Bangladeshi News Organization, Arif Md Tareque Habib
Influences Of The Western Press On News Framing Of Global Events In Developing Countries: Examining Covid-19 And Climate Coverage In A Bangladeshi News Organization, Arif Md Tareque Habib
Communication ETDs
This study shows that a small number of Western news organizations (e.g., Reuters, The New York Times) may influence how local news organizations in developing countries frame global crises and that this influence may lead local news organizations to ignore locally relevant aspects of those crises. To test this thesis, two studies were conducted on the coverage of two crises -- COVID-19 and climate change -- by a news organization in Bangladesh, a developing country in South Asia. The news organization, www.bdnews24.com, serves both as a news agency or news supplier for local newspapers and an online newspaper for users. …
Shifting From Crisis To Prevention: Community-Generated Materials From The Core Sipp Listening Sessions (Version 1), Camille Velarde, Mahtab Soleimani, Yvonnie Baik, Theresa Cruz
Shifting From Crisis To Prevention: Community-Generated Materials From The Core Sipp Listening Sessions (Version 1), Camille Velarde, Mahtab Soleimani, Yvonnie Baik, Theresa Cruz
Reports & Documents
The Core State Injury Prevention Program (CORE SIPP) in New Mexico sought to understand how communities can prevent injury and violence before crisis occurs. In 2025, the University of New Mexico Prevention Research Center, in partnership with the New Mexico Department of Health, listened to service providers, advocates, and community leaders working with youth and families across the state. Participants described overlapping challenges, including poverty, unsafe housing, limited mental health care, transportation gaps, and a lack of safe spaces for young people, and emphasized that real prevention must start early and address families’ basic needs. From these sessions, community members …
Advancing Interactive Web Cartography Through Designing And Developing An Open-Source, Data-Driven Framework For Accessible Geovisualization Of Geospatial (Big) Data, Sarigai Sarigai
Geography ETDs
The growth of geospatial big data has intensified the demand for open-source, accessible tools for interactive spatial exploration. This dissertation introduces a modular web mapping framework and details its design, extension, and evaluation to advance geovisualization through user-centered, transferable design. The first study presents the original framework, named dciWebMapper, establishing foundational cartographic and information visualization principles, with a focus on modularity and extensibility. The second study extends dciWebMapper with advanced capabilities—such as diverse map types, bivariate visualizations, temporal filtering, spatial querying, and hotspot analysis—and demonstrates its broad transferability across domains. The third study offers a structured usability evaluation of …
Coaching Bilingual Speech-Language Student Clinicians And Spanish-Speaking Caregivers To Use Culturally Adapted Ndbi Techniques For Autistic Preschoolers, Richelle R. Mcguire
Coaching Bilingual Speech-Language Student Clinicians And Spanish-Speaking Caregivers To Use Culturally Adapted Ndbi Techniques For Autistic Preschoolers, Richelle R. Mcguire
Speech and Hearing Sciences ETDs
This study used a cascading coaching model to train bilingual speech-language pathology graduate students and Spanish-speaking caregivers to implement naturalistic developmental behavioral intervention (NDBI) strategies with autistic preschoolers. Two triads, each including a student clinician, minimally vocal child with autism, and caregiver, participated. A monolingual instructor coached student clinicians in culturally adapted NDBI techniques, who then coached caregivers in Spanish. A mixed methods approach evaluated outcomes through single-case experimental design and qualitative interviews. All adult participants increased their use of targeted NDBI skills, with large to very large effect sizes. Qualitative findings suggested areas for improvement (e.g., need for more …
Hyperglycemia And Oral Health: A Review Of Dental Clinicians’ Perceptions And Practices Of Blood Glucose Monitoring In The Dental Office, Kathleen Wozniak
Hyperglycemia And Oral Health: A Review Of Dental Clinicians’ Perceptions And Practices Of Blood Glucose Monitoring In The Dental Office, Kathleen Wozniak
Dental Hygiene ETDs
This study aims to review the current practices and perceptions of dentists regarding the likelihood of dental professionals incorporating blood glucose monitoring into patient care protocol of patients with diabetes mellitus and prediabetes in dental offices. A survey link was shared by DentalOffices, a dental resource center. The survey included a series of questions which aimed to review dentists' current attitudes, practices, and considerations for implementation of in-office blood glucose testing as it relates to the treatment of patients with diabetes mellitus. Forty-seven dentists participated in the survey. This study determined blood glucose testing is not a common protocol or …
Citizen Science Helps Monitor Urban Biodiversity: An Interactive, Data-Driven, And Open-Source Perspective, Katie Slack
Citizen Science Helps Monitor Urban Biodiversity: An Interactive, Data-Driven, And Open-Source Perspective, Katie Slack
Geography ETDs
Story maps, a powerful tool for communicating environmental narratives, are often commercial and lack many interactive functions. We integrate a data-driven and interactive geovisualization within an open-source story map created from high-attribute citizen science datasets. This story map creates a backend programming infrastructure for accessible, open-source science communication tools. Our story map intuitively communicates the findings from our web map application (app) portion of the story map to the public and helps reveal findings from the iNaturalist datasets. Albuquerque, New Mexico, United States is a demonstrative case study, but our tools can be flexibly adapted to other cities. Geovisualizations revealed …
Health Impacts, Air Pollution And Electric Vehicles In California, Pufan Qi
Health Impacts, Air Pollution And Electric Vehicles In California, Pufan Qi
Economics ETDs
This research examines the impact of electric vehicles (EVs) on air quality in California over the period from 2010 to 2021, as well as the implications of air pollution for respiratory health, organized into five chapters. The initial chapter provides background information and outlines the objectives, findings, and contributions. The second chapter examines the relationship between air quality and electric vehicles by utilizing fixed effect panel regression models. The third chapter employs panel regressions with Poisson control models to assess the correlation between changes in air quality resulting from electric vehicles and the prevalence of respiratory diseases. The fourth chapter …
Essays On The Economics Of Education Policy, Stephen Owusu
Essays On The Economics Of Education Policy, Stephen Owusu
Economics ETDs
The first chapter of this dissertation evaluates the impact of Ghana’s Capitation Grant Scheme, a government education policy that provides direct funding to public schools to eliminate primary school fees, on both the short- and long-term numeracy and literacy skills of children intended to be treated. The findings suggest that free primary education may exacerbate language competition in linguistically discordant societies. In the second chapter, we find that, even without complementary infrastructural expansion, an additional year of official secondary schooling positively affects secondary and post-secondary educational outcomes. The third chapter investigates the relationship between secondary education length reform and reproductive …
Derivation Of Adjoint Based Error Estimates For Nonlinear Ordinary Differential Equations With Application To Multistage Sir Models With Demographics, Daniel Alcala
Mathematics & Statistics ETDs
Ordinary Differential Equations (ODEs) are central to the mathematical modeling of various real-world phenomena, from mechanical systems governed by Newton’s laws to epidemic dynamics described by SIR-type ODEs. Since many ODEs do not admit closed-form analytic solutions, we approximate them numerically (e.g., with Euler’s, Runge–Kutta, or other such methods). This raises the key question: How accurate are these numerical solutions? In particular, reliably estimating the error in some quantity of interest (QoI) at time T without having an exact solution is of great scientific interest.
The first main contribution of this thesis is the development and analysis of adjoint-based error …
Ecoimmunology Of Dirty Physella Acuta Snails, Kevin Arthur Mcquirk
Ecoimmunology Of Dirty Physella Acuta Snails, Kevin Arthur Mcquirk
Biology ETDs
Research on Physella acuta, an invasive freshwater snail, reveals insights into its parasitology, fitness, and molecular biology. Morphological and molecular analyses revealed two distinct mitogenomic lineages, local (B) and invasive (A) strains of native P. acuta, both having comparable trematode infection rates, suggesting that the low infection rates observed from A in invaded regions result from "enemy release" rather than immune incompatibility. Fitness assessments showed that while lineages A and B performed similarly under laboratory conditions, rewilding experiments revealed significantly higher fitness in lineage A. Transcriptomic profiling supported these differences, with A snails showing greater immune-related gene expression and …
A Data-Driven Approach To Time Series Forecasting And Clustering Of U.S. Regional Drug Overdose Mortality, Koshali Hamy Muthunama Gonnage
A Data-Driven Approach To Time Series Forecasting And Clustering Of U.S. Regional Drug Overdose Mortality, Koshali Hamy Muthunama Gonnage
Mathematics & Statistics ETDs
The increasing rate of drug overdose deaths in the United States poses a critical public health challenge, particularly due to the surge in synthetic opioids and other high-risk substances. This study presents a data-driven framework that integrates time series forecasting and clustering techniques. Monthly mortality data for five key drug types: cocaine, fentanyl, heroin, methamphetamine, and oxycodone were analyzed using four time series forecasting models: ARIMA, ETS, TBATS, and NNAR. These models were evaluated using standard accuracy metrics RMSE, MAPE, and MAE to assess predictive performance. Signal decomposition approach based on Singular Value Decomposition and subspace modeling was employed to …
• Social Media Use Among Undergraduate Women: Associations With Body Image, Disordered Eating, And Well-Being, Kirsten P. Peterson
• Social Media Use Among Undergraduate Women: Associations With Body Image, Disordered Eating, And Well-Being, Kirsten P. Peterson
Psychology ETDs
Though prior research has identified a range of negative impacts associated with social networking site/app (SNS) use, these effects vary and are often attributed to specific aspects of SNSs rather than time spent on them. The current study examined relations between SNS use and various psychological outcomes (i.e., body appreciation, body dissatisfaction, eating pathology, depression, and self-esteem) and how these may differ by platform, proportion of image-based content, image subjects, and passive (relative to active) use. Worse outcomes were anticipated for individuals who primarily used appearance-focused platforms and those with greater exposure to image-based content, self or celebrity images, and …
Cultural Risk And Protective Factors Associated With Sexual Assault Among Hispanic And Non-Hispanic White Women, Daisy Ramos
Cultural Risk And Protective Factors Associated With Sexual Assault Among Hispanic And Non-Hispanic White Women, Daisy Ramos
Psychology ETDs
There is a paucity of research on sexual assault among Hispanic college women. Existing studies indicate that Hispanic college women report similar mental health sequelae as non-Hispanic White women following a sexual assault; thus, factors that protect or increase their risk is an area worthy of further investigation. Latino cultural values, such as familism, may serve as a protective factor for sexual assault among Hispanic college women, while acculturation with mainstream culture may function as a risk factor. This study examined whether ethnicity moderated the effects of cultural protective and risk factors on sexual assault experiences among Hispanic and non-Hispanic …
Using Triple Oxygen Isotopes To Investigate Water Usage In Desert Ecosystems, Cloe V. Knutson
Using Triple Oxygen Isotopes To Investigate Water Usage In Desert Ecosystems, Cloe V. Knutson
Earth and Planetary Sciences ETDs
In arid environments, maintaining water balance can be more critical for survival than obtaining food. As droughts intensify, understanding how animals manage body water is essential. Triple oxygen isotope analysis provides a novel way to trace water sources in animals, distinguishing contributions from free water, food-derived oxygen, and atmospheric O2. We developed an equilibration method using CO2–H2O oxygen exchange and measured δ’18O and Δ’17O values via tunable infrared laser direct spectroscopy (TILDAS). Validated against traditional fluorination methods, this technique enables streamlined analysis of whole blood and plant samples. Applied to …
An Analysis Of Employment Patterns And Career Decisions Among Dental Hygienists: In A Transforming Healthcare Landscape, Shirley Calderon Jamarck
An Analysis Of Employment Patterns And Career Decisions Among Dental Hygienists: In A Transforming Healthcare Landscape, Shirley Calderon Jamarck
Dental Hygiene ETDs
The purpose of this study was to identify the factors contributing to dental hygienists’ consideration of changing careers, retiring early, or feeling burned out. A 26-question survey was emailed to members of the American Dental Hygienists’ Association, with 742 responses meeting inclusion criteria. Participants evaluated aspects of their careers, including job satisfaction, wages and benefits, personal growth, work-related stress, burnout, work-life balance, and retirement plans. Results revealed that one-third of respondents planned to leave the profession, citing burnout, physical strain, and limited career growth as reasons. High correlations were found between job satisfaction and feeling valued, professional accomplishment, and growth …
Lifestyle Factors Contributing To Occupational Heat-Related Acute Kidney Injury, Jonathan Specht, Fabiano Amorim, Flavio De Castro Magalhaes, Zachary Mckenna, Zachary Schlader
Lifestyle Factors Contributing To Occupational Heat-Related Acute Kidney Injury, Jonathan Specht, Fabiano Amorim, Flavio De Castro Magalhaes, Zachary Mckenna, Zachary Schlader
Health, Exercise, and Sports Sciences ETDs
Workers worldwide are at risk for acute kidney injury due to hyperthermia and dehydration as a consequence of exertional heat stress. Limited research has explored the impact which lifestyle agents such as beverages, recreational drugs, and medications have on core temperature, hydration, and risk of acute kidney injury during physical work in the heat. To address this research gap, we explored the impact of three agents frequently used by construction workers on thermoregulation and markers of risk of acute kidney injury. First, we investigated the effect which ibuprofen ingestion has prior to one hour of running in the heat on …
Addressing Head Injuries In High School Football: An Assessment Of Best Practices And Challenges In The Area Of Concussions As Held By New Mexico Activities Association High School Varsity Football Head Coaches And Athletic Directors, Alonzo Maestas
Health, Exercise, and Sports Sciences ETDs
Youth sports participation in the United States offers children and adolescents opportunities for physical activity, skill development, social interaction, and personal achievement. However, with sports comes the risk of injury, including concussions. Concussions can have serious long-term consequences such as chronic traumatic encephalopathy (CTE). In response to the risks of concussions, New Mexico enacted a concussion law, NM Stat 22-13-31. In addition to this law, the New Mexico Activities Association (NMAA) and National Federation of High School Associations (NFHS) have also given guidance on how to manage concussions.
However, there is a gap in the literature concerning concussion education, best …
Making The Macc: Communities Of Practice And Cultural Citizenship In Austin, Texas, Cassie Lynn Smith
Making The Macc: Communities Of Practice And Cultural Citizenship In Austin, Texas, Cassie Lynn Smith
Anthropology ETDs
Meaningful community engagement is a challenge for local governments without a thorough understanding of constituents’ histories and their relationship with City government. This dissertation investigates the City of Austin’s (COA) Emma S. Barrientos Mexican American Cultural Center (MACC) in Austin, Texas, to understand how this culture and arts institution engages with and is influenced by its patrons. This study analyzes the role of the MACC’s community of practice (Lave and Wenger 1991)—an evolving group of educators, activists, artists, and COA staff—in shaping public policy and educational programming as well as creating places of belonging for marginalized people in the city. …
Microneedle-Based Lc-Ms/Ms Profiling Of Dermal Interstitial Fluid Reveals Early Lipid Dysregulation Contributing To Painful Neuropathy In Prediabetic And Type 2 Diabetic Rats, Srinivasa Rao Gadam
Microneedle-Based Lc-Ms/Ms Profiling Of Dermal Interstitial Fluid Reveals Early Lipid Dysregulation Contributing To Painful Neuropathy In Prediabetic And Type 2 Diabetic Rats, Srinivasa Rao Gadam
Biomedical Sciences ETDs
Painful diabetic neuropathy (PDN), a complication of type 1 and type 2 diabetes, also occurs in obesity and prediabetes, with dyslipidemia as a modifiable risk factor. The distal-to-proximal neuropathy pattern and length-dependent intraepidermal nerve fiber loss suggest peripheral contributions. We hypothesized that elevated neurotoxic lipid intermediates—diacylglycerols (DAG), free fatty acids (FFA), and acylcarnitines (CARs)—in the dermal interstitial fluid (ISF) drive metabolism-associated hyperalgesia in prediabetic and diabetic rats. Using a microneedle array (MIA) with LC-MS/MS, we profiled ISF and serum lipids from high-fat diet (HFD) and HFD + streptozotocin (STZ) rat models alongside Hargreaves testing. ISF lipid changes appeared earlier (weeks …
Exploration, Expansion, And Optimization Of Bacteriophage Virus-Like Particle Vaccines, Andzoa N. Jamus
Exploration, Expansion, And Optimization Of Bacteriophage Virus-Like Particle Vaccines, Andzoa N. Jamus
Biomedical Sciences ETDs
Bacteriophage virus-like particles are highly immunogenic, self-assembling platforms used for various vaccines. This work shows efforts to explore new vaccine candidates against Chlamydia trachomatis, targeting proteins that play critical roles in attachment and entry into the host cell, as well as in pathogenesis and bacteria proliferation. This work also shows the optimization of previously identified candidates, by investigating how altering routes of immunization can change the antibody profiles elicited, both systemically and locally. Finally, this work shows the establishment of various Chlamydia infection models in an effort to expand the ways in which vaccine efficacy can be investigated, particularly …
Immune Regulation In Fungal Airway Inflammation And Host Defense, Ruoning Wang
Immune Regulation In Fungal Airway Inflammation And Host Defense, Ruoning Wang
Biomedical Sciences ETDs
Asthma is a chronic inflammatory disease of the lungs characterized by complex pathophysiological mechanisms and diverse endotypes, primarily categorized as T helper type 2 cell (Th2)-high and Th2-low asthma. Despite significant advances in understanding asthma pathogenesis, the mechanisms governing the pulmonary immune system’s response to external challenges have not been fully understood. To address these gaps, this comprehensive project was designed to investigate the interplay between fungal infections and specific CD4+ T cell populations in asthma. Our findings suggest that fungal infections can contribute to neutrophilic asthma by promoting the migration of platelet-myeloid aggregates into the lungs. We also …
Localization Of Alpha Power Deficits In First Episode Psychosis, Crystal A. Garcia, Juan Bustillo
Localization Of Alpha Power Deficits In First Episode Psychosis, Crystal A. Garcia, Juan Bustillo
Biomedical Sciences ETDs
The purpose of this study was to determine where in the brain there may be a difference in brain activity in patients during their first episode of psychosis (FEP) compared to healthy controls (HCs) while performing an auditory oddball task. Time-frequency analysis allows for spectral decomposition where the signal measured by magnetoencephalography (MEG) is used to characterize changes in neural oscillations and their synchronization over time and region. Previous EEG studies report reduced alpha (8-12Hz, 70-160ms) power but most studies focused on patients with chronic schizophrenia and with limited source localization.
A Mutational Analysis Of Thatisin: How Single Point Mutations Impact The Biosynthetic Process Of A Group 16 Graspetide, John F. Boynton Jr
A Mutational Analysis Of Thatisin: How Single Point Mutations Impact The Biosynthetic Process Of A Group 16 Graspetide, John F. Boynton Jr
Chemistry and Chemical Biology ETDs
Abstract:
Graspetides are a family of Ribosomally synthesized and Post-translationally modified Peptide (RiPP) natural products named for their ATP Grasp Macrocyclases. We identified several Graspetide Biosynthetic Gene Clusters containing common double glycine cleavage motifs and attempted characterization of the mature Graspetides. One of the resulting peptides, Thatisin, has a topology with two interlocking macrolactones installed by a single ATP Grasp Ligase named ThtC. Here we use single and double point mutations to observe the impact or variation on the installation of these macrocycles. Alanine scan mutagenesis is used to assess leader peptide residues in the precursor peptide ThtA to determine …
Finite Element Investigation Of Blast Load Responses In Nuclear Power Plant Containment Structures, Janak Raj Awasthi
Finite Element Investigation Of Blast Load Responses In Nuclear Power Plant Containment Structures, Janak Raj Awasthi
Civil Engineering ETDs
Some significant incidents like the Chernobyl disaster (1986), the Fukushima Daiichi hydrogen explosion (2011), and some frequent military and terror threats to the nuclear Power plant structures have led to studying the capacity of power plant structures to withstand blast loadings. From this research, even one-third of the loss of the coolant is enough to damage the power plant structure. Crack starts from the wall and propagates toward the top of the dome and the foundation. The external blast shows high damage symptoms near the foundation area. Most of the steel members, including the rebars, Liner, and Tendons, showed high …
Understanding The Metallic And Oxide Phases In Platinum-Based Bimetallic Heterogeneous Catalysts After High-Temperature Oxidation, Stephen John Porter Jr
Understanding The Metallic And Oxide Phases In Platinum-Based Bimetallic Heterogeneous Catalysts After High-Temperature Oxidation, Stephen John Porter Jr
Nanoscience and Microsystems ETDs
Platinum (Pt) and palladium (Pd) are critical components in diesel emission control systems, enabling the conversion of harmful pollutants under demanding conditions. However, Pt’s effectiveness is hindered by sintering under high-temperature oxidizing environments. This dissertation investigates how Pt and Pd evolve under oxidizing conditions at 800°C, highlighting their distinct thermodynamic behaviors and interactions. Using TEM, EDS, EELS, XRF, XRD, and EXAFS, we show that Pd suppresses Pt sintering by reducing the volatility of PtO₂, leading to the formation of stable particles. Both Pt and Pd are present in metallic and oxide states, forming biphasic 'Janus' particles with conjoined metal and …
Advancements In Microarray Manufacturing Enable Emerging Technologies, Kendall Hoff
Advancements In Microarray Manufacturing Enable Emerging Technologies, Kendall Hoff
Biomedical Engineering ETDs
Significant advances in manufacturing technologies have enabled the production of new DNA microarrays for use in emergent technology. Photolithography, wafer scale manufacturing, and improvements in synthesis chemistry and design enable high-throughput production of extremely high-quality arrays. These new arrays offer extremely high oligonucleotide densities, in the range of tens of thousands of oligonucleotides per square micron. They also offer smaller features sizes, with millions of features per square centimeter. Furthermore, they can be manufactured with the DNA tethered at either end to the surface, leaving either the 5’ or 3’ end free and available for use in enzymatic reactions; and …
Exploring Immune System Through Computational Modeling: A Comprehensive Study Of Lymph Nodes And Immune Response Scaling, Vaccine Efficacy, And Large-Scale Extreme First Passage Time, Jannatul Ferdous
Computer Science ETDs
The adaptive immune response is a complex defense mechanism that develops over time to recognize and eliminate pathogens with remarkable precision and durability. This dissertation investigates the dynamics, scaling, and efficiency of the adaptive immune response through a synthesis of computational modeling, mathematical analysis, and agent-based simulations. First, we analyze the topology of the lymphatic network and investigate the T cell search time to find the lymph node that is containing the matching dendritic cell. Second we show how the scaling of lymph node number and volume with body mass, leads to scale-invariant search times for T cells locating antigen-bearing …
Secured Through Stone: The Power, Monuments, And Memory Of Thyra Danmarkarbót And The Jelling Dynasty, Jacquelyn Truitt
Secured Through Stone: The Power, Monuments, And Memory Of Thyra Danmarkarbót And The Jelling Dynasty, Jacquelyn Truitt
History ETDs
Sometime in the mid-tenth century on the Jutland peninsula of Denmark, the Viking Age Queen Thyra (d. ca. 958/9) passed away and the epithet Danmarkarbót—Denmark’s Adornment—was skillfully carved onto her memorial runestone. Yet Thyra’s story has been clouded by few and unreliable textual sources, by differing assessments of her familial background that have emerged from those sources, and by misrepresentations of the material culture relating to her. This thesis explores Thyra and her place within the Viking Age Jelling dynasty through textual and material evidence and considers how the construction of both medieval and modern memory work and memorialization …
Network Intelligence For Next-Generation Wireless Networks: Advancing Distribution And Coordination, Yonatan Melese Worku
Network Intelligence For Next-Generation Wireless Networks: Advancing Distribution And Coordination, Yonatan Melese Worku
Electrical and Computer Engineering ETDs
Next-generation wireless networks, encompassing 6G and beyond, face rigorous demands for ultra-low latency, ubiquitous connectivity, exceptionally high data rates, and robust security, necessitating innovative approaches to resource optimization and network protection. This dissertation proposes a pioneering framework that synergizes advanced methodologies—deep reinforcement learning, deep learning, blockchain, and multi-agent systems—to address these challenges. Distributed architectures, underpinned by AI-driven multi-agent systems, form the backbone of this framework, enabling seamless integration and intelligent orchestration across diverse domains. The research advances IoT-based systems leveraging machine learning for resource efficiency in healthcare applications, develops reinforcement learning-driven frameworks to optimize energy and coverage for Unmanned Aerial …