Digital Commons Network^™

Precision Medicine Approaches To Alcohol Use Disorder For American Indians: Assessment And Phenotypic Differentiation Of Reward And Relief Drinking, Hanna M. Hebden

Psychology ETDs

American Indian (AI) communities endorse high rates of abstinence from alcohol and substance use, yet experience disparate rates of alcohol and substance-related consequences. Alcohol and substance use is conceptualized as interwoven with unique AI contextual factors, which are often not incorporated into examination of related constructs. Current knowledge gaps exist in study of precision medicine approaches to treatment for reward and relief drinking in AI. This study aimed to understand reward and relief substance use phenotypes in AI. We described a contextually-informed model of relief assessment and to compare this assessment to the original reward and relief models using latent …

Public Support For Community Microgrid Services, Janie M. Chermak, Jesse Ian Kaczmarski

SMART Grid Center (NM EPSCoR RII V)

Survey instrument, codebook, summary statistics, and simulation code in STATA v16.1 format for the analysis reported in:

Kaczmarski, Jesse I. "Public support for community microgrid services." Energy Economics 115 (2022): 106344. https://doi.org/10.1016/j.eneco.2022.106344

Accompanying files include a STATA log file and a README. Information from the README file is also included below.

Per the consent language in the included survey instrument, raw data from the reported study are not publicly available.

This readme file was generated on 2023-02-20 by Jesse Kaczmarski

GENERAL INFORMATION

Title of Dataset: Public Support for Community Microgrid Services

Principal Investigator Information Name: Janie Chermak ORCID: N/A Institution: …

Evaluating A Web-Based Training Curriculum For Disseminating Best Practices For The Care Of Newborns With Neonatal Opioid Withdrawal Syndrome In A Rural Hospital, The Nows-Nm Program, Heather Pratt-Chavez, Heidi Rishel Brakey, Sarah G. Sanders, Juhee Patel, Tim Ozechowski, Chloe Stoffel, Andrew L. Sussman, Jessie Marquez, David R. Smith, Alberta S. Kong

Pediatrics Research and Scholarship

BACKGROUND: The incidence of neonatal opiate withdrawal syndrome (NOWS) in the US has grown dramatically over the past two decades. Many rural hospitals not equipped to manage these patients transfer them to hospitals in bigger cities.

METHODS: We created a curriculum, the NOWS-NM Program, a mobile/web-based curriculum training in best practices. To evaluate the curriculum, we conducted pre- and post-surveys of NOWS knowledge, attitudes, and care practices, plus post-curriculum interviews and focus groups.

RESULTS: Fourteen participants completed both pre- and post-curriculum surveys. They indicated an increase in knowledge and care practices. A small number of respondents expressed negative attitudes about …

Machine Learning Methods For Computational Phenotyping Using Patient Healthcare Data With Noisy Labels, Praveen Kumar

Computer Science ETDs

Positive and Unlabeled (PU) learning problems abound in many real-world applications. In healthcare informatics, diagnosed patients are considered labeled positive for a specific disease, but being undiagnosed does not mean they can be labeled negative. PU learning can improve classification performance, and estimate the positive fraction, α, among unlabeled samples. However, algorithms based on the Selected Completely At Random (SCAR) assumption are inadequate when the SCAR assumption fails (e.g., severe cases overrepresented), and when class imbalance is substantial. This dissertation presents and evaluates new algorithms to overcome these limitations. The proposed methods outperform the state-of-art for α-estimation, enhance classification performance, …

The Onset Of Rare Earth Metallosis Begins With Renal Gadolinium-Rich Nanoparticles From Magnetic Resonance Imaging Contrast Agent Exposure, Joshua Deaguero, Tamara Howard, Donna Kusewitt, Adrian Brearley, Abdul-Mehdi Ali, James H. Degnan, Stephen Jett, John Watt, G Patricia Escobar, Karol Dokladny, Brent Wagner

Pathology Research and Scholarship

The leitmotifs of magnetic resonance imaging (MRI) contrast agent-induced complications range from acute kidney injury, symptoms associated with gadolinium exposure (SAGE)/gadolinium deposition disease, potentially fatal gadolinium encephalopathy, and irreversible systemic fibrosis. Gadolinium is the active ingredient of these contrast agents, a non-physiologic lanthanide metal. The mechanisms of MRI contrast agent-induced diseases are unknown. Mice were treated with a MRI contrast agent. Human kidney tissues from contrast-naïve and MRI contrast agent-treated patients were obtained and analyzed. Kidneys (human and mouse) were assessed with transmission electron microscopy and scanning transmission electron microscopy with X-ray energy-dispersive spectroscopy. MRI contrast agent treatment resulted in …

Psychometrics At A Glance: What Does Item Analysis Tell Us?, Katherine Grand

HSC Education Days

The purpose of this work is to help educators improve assessments using item analysis. It is important to assess if the student made a connection of what was taught or learned. If exams are too easy this could lead to low motivation, or exams are too hard it could lead to student frustration or lack of confidence. The purpose of this poster will teach the teacher on how to interpret assessments using item analysis both item quality (difficulty index, discrimination index, and point biserial), and exam quality (Kuder-Richardson 20 (KR-20).

Care Through Connection: Patient Mutuality And Working Alliance Curriculum, N Mariam Salas, Kathryn Lenberg

HSC Education Days

Background: There is clear evidence in the psychology literature that beyond “people skills,” providers who give the patient an active role in developing the treatment plan can increase the adherence to the medical plan by 70%. Though this is utilized extensively in psychology, medical trainees are not routinely taught these communication skills. To arm our fellows with these necessary skills, we worked with our clinical psychologist, Dr. Kathryn Lenberg, to develop an integrated curriculum over the 2-year period of the fellowship. Implementation: We began a phased roll out of the curriculum in 2020. During elective rotations, fellows spent 1 hour …

New Approaches To Case Studies To Prepare Student Nurses For Next-Generation Nclex And Clinical Practice, Christopher Nelson, Crystal Sanchez

HSC Education Days

In the setting of patients with increased complexity and record attrition, more is required of newly-graduated nurses than ever before. Novice nurses struggle to make clinical judgments at the same level as their more experienced counterparts. Nursing scholars have investigated what can be done to better prepare student nurses for the challenges of modern nursing practice. How does one develop or enhance students’ clinical judgment? Was the nursing licensing exam (NCLEX) reliably measuring novice nurses’ ability to use clinical judgment? The National Council of State Boards of Nursing designed the Clinical Judgment Measurement Model (CJMM) to better measure decision-making. The …

Continuous Education For Prite A “For Residents”, “By Residents” Approach, David Andrade, Dominique Price

HSC Education Days

The Psychiatry Resident-In-Training Examination (PRITE®) is an annual examination designed as a point of reference to track competency for psychiatric residents and training programs. PRITE® scores have historically shown significant correlation with board results, however the preparation for PRITE® has become increasingly problematic. Due to limitations of didactic time and faculty as well as escalating clinical responsibilities for residents, exam preparation has been de-prioritized and disorganized. Self- study blocks led to suboptimal review lacking in structure with unclear goals and inadequate follow up. Residents wanted relevant, accessible, and continuous preparation for the PRITE®. In the winter of 2021, “Continuous education …

The Serial Effect, Kat Albrecht, Kaitlyn Filip

New Mexico Law Review

The “CSI Effect” theorizes that criminal juries can be unduly influenced by fictional crime dramas such that they demand a higher standard of forensic evidence than is available, or even possible to provide, in most criminal cases. The CSI Effect has a strong presence in the courtroom despite its narrow focus on forensic evidence and basis in fiction. This article explores a new media-induced effect that may prove to affect American juries even more insidiously: The Serial Effect. This article explores the rise of true crime podcasts and the legal cases featured within them through focus on Syed v. Maryland …

Independent Analysis And Interpretation Of The New Mexico Constitution: If Not Now, When?, The Honorable Linda M. Vanzi, Mark T. Baker

New Mexico Law Review

This article posits that the mode of analysis of state constitutional issues adopted by the New Mexico Supreme Court in State v. Gomez, as it has been applied in the civil context, has neither “promote[d] the development of a sound body of state constitutional jurisprudence” nor led to “consistent, predictable, and reasonable state court decision-making,” as some envisioned in 1998. Instead, it has often led to essentially automatic deference to federal precedent interpreting comparable provisions of the Federal Constitution and very limited, if any, consideration of protections afforded under our state constitution. In addition, the inconsistent application of the Gomez …

New Mexico’S Just Deserts: How The State’S Sentencing Policies Have Negatively Affected Criminal Justice, Oliver M. Stephanz

New Mexico Law Review

This Article takes an empirical, data-driven approach to evaluate New Mexico’s sentencing program against those used throughout the nation. In so doing, it uses three primary factors to weigh the “success” of the state’s sentencing policies: (1) incarceration rates, (2) crime rates, and (3) recidivism. These factors are used because data from the last 40 years show that each one is affected by the type of sentencing system used in a given jurisdiction. Studies further indicate that specific types of sentencing systems are strongly correlated with lower crime, lower numbers of incarcerated individuals, and less recidivism among convicted offenders. This …

Gaps In The Screening Process For Women Diagnosed With Cervical Cancer In Four Diverse Us Health Care Settings, Chun R. Chao, Jessica Chubak, Elisabeth F. Beaber, Aruna Kamineni, Connie Mao, Michael J. Silverberg, Jasmin A. Tiro, Celette Skinner, Michael Garcia, Douglas A. Corley, Rachel L. Winer, Tina Raine-Bennett, Sarah Feldman, Cosette M. Wheeler

Pathology Research and Scholarship

BACKGROUND: Potential care gaps in the cervical cancer screening process among women diagnosed with cervical cancer in an era with increased human papillomavirus (HPV) testing have not been extensively evaluated.

METHODS: Women diagnosed with cervical cancer between ages 21 and 65 at four study sites between 2010 and 2014 were included. Screening histories were ascertained from 0.5 to 4 years prior to cervical cancer diagnosis. We identified potential care gaps in the screening history for each woman and classified them into one of three mutually exclusive types: lack of a screening test, screening test failure, and diagnostic/treatment care gap. Distributions …

State V. Gutierrez Abolishing The Spousal Communications Privilege: An Opinion Raising Profound Questions About The Future Of Evidentiary Privileges In The United States, Edward J. Imwinkelried

New Mexico Law Review

Part I of this article is a detailed description of the original Gutierrez decision, the dissents as well as the majority opinion. Part II then critically evaluates the majority’s analysis of the application of the instrumental theory to the spousal communications privilege. Part II argues that the majority correctly concluded that the instrumental case for the spousal privilege is weak. The majority rigorously applied the instrumental criteria to the privilege and came to the honest, realistic conclusion that, in most cases, spouses would consult and confide even if there were no spousal privilege. However, Part II points out that the …

Particle-In-Cell Simulations Of Plasma Sheath Effects On A Whistler Wave Electric Dipole Antenna Operating In The Magnetosphere, Kevin A. Shipman

Electrical and Computer Engineering ETDs

A coronal mass ejection or a high-altitude nuclear explosion can produce an artificial radiation belt containing high-energy electrons (~1MeV) in the Earth's magnetosphere. Some electrons become trapped in the Earth's magnetic field and have enough energy to severely damage or destroy nearly all lower-earth orbit (LEO) satellites. Over the years, there has been much interest in using a space-borne dipole antenna to inject very low frequency (VLF) whistler waves (3-30kHz) along the Earth's magnetic field lines. The whistler waves precipitate the electrons from the magnetosphere through a wave-particle interaction called pitch-angle scattering. However, because the magnetosphere is composed of plasma, …

Katz Or Dogs? Why The Katz Reasonable Expectation Of Privacy Test Is More Applicable To Advancing Technology Than A Test Applied To Dog Sniffs, Blade M. Allen

Student Published Scholarship

Most often, when law enforcement agencies or governments use a person’s DNA or genetic information, they do so in the pursuit of justice. That said, there are privacy concerns that arise when the government or police have open access to any person’s DNA or genetic information, especially through the Internet. This article attempts to present an argument for a reasonable expectation of privacy (REP) in a person’s genetic information or DNA as well as other forms of advancing technology. It begins with a history of the US Supreme Court’s interpretations of the Fourth Amendment to the US Constitution, continues with …

Why The Actual Malice Test Should Be Eliminated, John M. Kang

Faculty Scholarship

Under traditional common law, a plaintiff could recover damages for libel if she could prove that the defendant had published a factual statement about the plaintiff that tended to injure the plaintiff’s reputation. The plaintiff, at most, was required to show negligence to recover damages for libel. While the amount of money that any given plaintiff could recover in damages was uncertain, one thing was clear: the First Amendment would not protect libel. In 1964, in New York Times Co. v. Sullivan, the Supreme Court radically upended this received view of libel as unprotected speech. According to Sullivan, …

Prenatal Cannabinoid Exposure: Why Expecting Individuals Should Take A Pregnancy Pause From Using Cannabinoid Products, Alexis Lin, Gelonia L. Dent, Suzy Davies, Zarena M. Dominguez, Leigh-Anne Cioffredi, Gabrielle L. Mclemore, Jessie R. Maxwell

Pediatrics Research and Scholarship

Cannabinoid use in all populations is increasing as legalization across the United States continues. Concerningly, there is a lack of caution provided by medical providers to pregnant individuals as to the impact the use of cannabinoids could have on the developing fetus. Research continues in both the preclinical and clinical areas, and is severely needed, as the potency of delta-9-tetrahydrocannabinol (THC), the primary psychoactive component of cannabis, has increased dramatically since the initial studies were completed. Thus far, clinical studies raise compelling evidence for short term memory deficits, impulse control issues, and attention deficiencies following prenatal cannabinoid exposure (PCE). These …

Resolving Conflict In The Operating Room – How A Communication Training Workshop Can Improve Faculty Competency, Aleezay Haider, Ronald Orozco, Rebecca Hohsfield, Ming-Li Wang, Baila Maqbool

Surgical Education

Our study demonstrates that a formal communication training initiative can boost faculty self-confidence in conflict resolution skills within the operating room. Using simulations tailored to the unique challenges of an OR setting equip surgeons with immediately transferable skills.

Evaluation Of Early Insulin Glargine Administration In The Treatment Of Pediatric Diabetic Ketoacidosis, Kelli J. Welter, Jessica L. Marquez, Patricia L. Marshik, Michael V Yao, Ellen S. Bickel

Pediatrics Research and Scholarship

OBJECTIVE: In the management of diabetic ketoacidosis (DKA), the standard of care is to administer insulin glargine after ketoacidosis has resolved and the patient is transitioning from intravenous (IV) insulin to subcutaneous insulin; however, there is evidence to suggest that earlier administration of insulin glargine may accelerate resolution of ketoacidosis. The objective of this research is to determine the efficacy of early subcutaneous insulin glargine on time to resolution of ketoacidosis in children with moderate to severe DKA.

METHODS: This retrospective chart review evaluated children age 2 to 21 years old admitted for moderate to severe DKA who received insulin …

Planned Adaptation And Implementation Of The Community Guide Recommendations For Increasing Physical Activity In Rural Community Settings: A Qualitative Study, Julia Meredith Hess, Sally M. Davis

Pediatrics Research and Scholarship

BACKGROUND: The purpose of this paper is to report on the implementation of an evidence-based model, VIVA, which was developed to translate physical activity (PA) recommendations to rural environments and was scaled-up to 12 rural communities across New Mexico. Our longitudinal qualitative research describes processes of planned adaptation in the rural context with an exploration of inner and outer context adaptations that consider important implementation constructs including leadership, partnership and collaboration.

MATERIALS & METHODS: An enhanced version of the RE-AIM framework was used to formulate community-level engagement and process questions essential to implementation science. Qualitative methods, using a thematic approach …

Pilot Study Shows Skin-To-Skin Care With Parents Improves Heart Rate Variability In Preterm Infants In The Neonatal Intensive Care Unit, Erin Swieter, Jessica M. Gross, Julia Stephen, Kristi Watterberg, Jessie R. Maxwell

Pediatrics Research and Scholarship

BACKGROUND: Skin-to-skin care in the newborn intensive care unit typically lasts for short periods of time and enhances breastfeeding, attachment, and parental self-esteem. Heart rate variability (HRV) increases with gestational age and is a measure of maturation of parasympathetic vs. sympathetic autonomic nervous system activity. HRV measurements may be useful in capturing changes in autonomic regulation in response to skin-to-skin care.

OBJECTIVE: To analyze the effects of skin-to-skin care on HRV in preterm infants receiving respiratory support. We hypothesized that skin-to-skin care would result in a more mature pattern of parasympathetic activity.

METHODS: In this prospective crossover study, infants <30 >weeks' …

Researching Covid To Enhance Recovery (Recover) Adult Study Protocol: Rationale, Objectives, And Design, Leora I Horwitz, Tanayott Thaweethai, Shari B Brosnahan, Mine S Cicek, Megan L Fitzgerald, Jason D Goldman, Rachel Hess, S L Hodder, Vanessa L Jacoby, Michael R Jordan, Jerry A Krishnan, Adeyinka O Laiyemo, Torri D Metz, Lauren Nichols, Rachel E Patzer, Anisha Sekar, Nora G Singer, Lauren E Stiles, Barbara S Taylor, Shifa Ahmed, Heather A Algren, Khamal Anglin, Lisa Aponte-Soto, Hassan Ashktorab, Ingrid V Bassett, Brahmchetna Bedi, Nahid Bhadelia, Christian Bime, Marie-Abele C Bind, Lora J Black, Andra L Blomkalns, Hassan Brim, Mario Castro, James Chan, Alexander W Charney, Benjamin K Chen, Li Qing Chen, Peter Chen, David Chestek, Lori B Chibnik, Dominic C Chow, Helen Y Chu, Rebecca G Clifton, Shelby Collins, Maged M Costantine, Sushma K Cribbs, Steven G Deeks, John D Dickinson, Sarah E Donohue, Matthew S Durstenfeld, Ivette F Emery, Kristine M Erlandson, Julio C Facelli, Rachael Farah-Abraham, Aloke V Finn, Melinda S Fischer, Valerie J Flaherman, Judes Fleurimont, Vivian Fonseca, Emily J Gallagher, Jennifer C Gander, Maria Laura Gennaro, Kelly S Gibson, Minjoung Go, Steven N Goodman, Joey P Granger, Frank L Greenway, John W Hafner, Jenny E Han, Michelle S Harkins, Kristine S P Hauser, James R Heath, Carla R Hernandez, On Ho, Matthew K Hoffman, Susan E Hoover, Carol R Horowitz, Harvey Hsu, Priscilla Y Hsue, Brenna L Hughes, Prasanna Jagannathan, Judith A James, Janice John, Sarah Jolley, S E Judd, Joy J Juskowich, Diane G Kanjilal, Elizabeth W Karlson, Stuart D Katz, J Daniel Kelly, Sara W Kelly, Arthur Y Kim, John P Kirwan, Kenneth S Knox, Andre Kumar, Michelle F Lamendola-Essel, Margaret Lanca, Joyce K Lee-Lannotti, R Craig Lefebvre, Bruce D Levy, Janet Y Lin, Brian P Logarbo, Jennifer K Logue, Michele T Longo, Carlos A Luciano, Karen Lutrick, Shahdi K Malakooti, Gail Mallett, Gabrielle Maranga, Jai G Marathe, Vincent C Marconi, Gailen D Marshall, Christopher F Martin, Jeffrey N Martin, Heidi T May, Grace A Mccomsey, Dylan Mcdonald, Hector Mendez-Figueroa, Lucio Miele, Murray A Mittleman, Sindhu Mohandas, Christian Mouchati, Janet M Mullington, Girish N Nadkarni, Erica R Nahin, Robert B Neuman, Lisa T Newman, Amber Nguyen, Janko Z Nikolich, Igho Ofotokun, Princess U Ogbogu, Anna Palatnik, Kristy T S Palomares, Tanyalak Parimon, Samuel Parry, Sairam Parthasarathy, Thomas F Patterson, Ann Pearman, Michael J Peluso, Priscilla Pemu, Christian M Pettker, Beth A Plunkett, Kristen Pogreba-Brown, Athena Poppas, J Zachary Porterfield, John G Quigley, Davin K Quinn, Hengameh Raissy, Candida J Rebello, Uma M Reddy, Rebecca Reece, Harrison T Reeder, Franz P Rischard, Johana M Rosas, Clifford J Rosen, Nadine G Rouphael, Dwight J Rouse, Adam M Ruff, Christina Saint Jean, Grecio J Sandoval, Jorge L Santana, Shannon M Schlater, Frank C Sciurba, Caitlin Selvaggi, Sudha Seshadri, Howard D Sesso, Dimpy P Shah, Eyal Shemesh, Zaki A Sherif, Daniel J Shinnick, Hyagriv N Simhan, Upinder Singh, Amber Sowles, Vignesh Subbian, Jun Sun, Mehul S Suthar, Larissa J Teunis, John M Thorp, Amberly Ticotsky, Alan T N Tita, Robin Tragus, Katherine R Tuttle, Alfredo E Urdaneta, P J Utz, Timothy M Vanwagoner, Andrew Vasey, Suzanne D Vernon, Crystal Vidal, Tiffany Walker, Honorine D Ward, David E Warren, Ryan M Weeks, Steven J Weiner, Jordan C Weyer, Jennifer L Wheeler, Sidney W Whiteheart, Zanthia Wiley, Natasha J Williams, Juan P Wisnivesky, John C Wood, Lynn M Yee, Natalie M Young, Sokratis N Zisis, Andrea S Foulkes

Pediatrics Research and Scholarship

IMPORTANCE: SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are ill-defined. The objectives of the Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC in Adults (RECOVER-Adult) are to: (1) characterize PASC prevalence; (2) characterize the symptoms, organ dysfunction, natural history, and distinct phenotypes of PASC; (3) identify demographic, social and clinical risk factors for PASC onset and recovery; and (4) define the biological mechanisms underlying PASC pathogenesis. …

Brain Structural Differences In Children With Fetal Alcohol Spectrum Disorder And Its Subtypes, Theresah Boateng, Kathryn Beauchamp, Faerl Torres, Chaselyn D. Ruffaner-Hanson, John Fl Pinner, Kishore Vakamudi, Cassandra Cerros, Dina E. Hill, Julia M. Stephen

Pediatrics Research and Scholarship

INTRODUCTION: The teratogenic effects of prenatal alcohol exposure (PAE) have been examined in animal models and humans. The current study extends the prior literature by quantifying differences in brain structure for individuals with a fetal alcohol spectrum disorder (FASD) compared to typically developing controls, as well as examining FASD subtypes. We hypothesized the FASD group would reveal smaller brain volume, reduced cortical thickness, and reduced surface area compared to controls, with the partial fetal alcohol syndrome (pFAS)/fetal alcohol syndrome (FAS) subtypes showing the largest effects and the PAE/alcohol-related neurodevelopmental disorder (ARND) subtype revealing intermediate effects.

METHODS: The sample consisted of …

Monitoring American Federalism: The History Of State Legislative Resistance, Christian G. Fritz

Faculty Book Display Case

As Americans have monitored federalism, they struggled with how a government based on sovereignty divided between nation and states might function. The Constitution’s shared sovereignty created an inherently dynamic federalism with almost continuous debates over the balance of power, making this testing of the balance of federalism and monitoring government central to the American constitutional order. Many constitutional debates involved the protection of slavery, yet other interests including debt, taxation, and police powers also played vital roles in shaping American federalism. State resistance to the national government utilizing the constitutional tool of interposition arose when the disequilibrium of federalism was …

Issue No. 118: Spring 2023

La Crónica de Nuevo México

Table of Contents

2 A Letter from the President

3 The Development of Political Jurisdictions in New Mexico, 1823 – 1846 by Robert J. Tórrez

12 Gallup’s Grocer by John Lewis Taylor

21 Focus on Diaspora Casts Apache Histories in New Light by Paul Conrad

26 The Spirit of Lucy – Its Cemetery by Denise Tessier

29 CSWR has historic Blackdom town plat by Nancy Brown-Martinez

31 New Books

32 HSNM remembers John Ramsay and J. Paul Taylor

Research Task 03 Matched Guise, Pdf File

El Español de Nuevo México y Colorado Contemporáneos

No abstract provided.

Harnessing Axonal Transport To Map Reward Circuitry: Differing Brain-Wide Projections From Medial Prefrontal Cortical Domains, Elaine L. Bearer, Christopher S. Medina, Taylor W. Uselman, Russell E. Jacobs

Pathology Research and Scholarship

Neurons project long axons that contact other distant neurons. Neurons in the medial prefrontal cortex project into the limbic system to regulate responses to reward or threat. Diminished neural activity in prefrontal cortex is associated with loss of executive function leading to drug use, yet the specific circuitry that mediate these effects is unknown. Different regions within the medial prefrontal cortex may project to differing limbic system nuclei. Here, we exploited the cell biology of intracellular membrane trafficking, fast axonal transport, to map projections from two adjacent medial prefrontal cortical regions. We used Mn(II), a calcium analog, to trace medial …

Reduced Time To Procedure For Gastrointestinal Bleeding After Warfarin Reversal With Four-Factor Complex Concentrate As Compared To Plasma, Hannah Spector, Hannah L. Mcrae, Tanzy Love, Kalynn Northam, Khaled Refaai, Marian A. Rollins-Raval, Majed A. Refaai

Pathology Research and Scholarship

BACKGROUND: Bleeding is a serious adverse effect of vitamin K antagonists (VKAs). Anticoagulation reversal is required in some acute cases. This is usually accomplished by plasma transfusion or four-factor prothrombin complex concentrate (4F-PCC). The aim of this study was to gain insight into the clinical course of patients with gastrointestinal (GI) bleeding who require VKA reversal.

METHODS: Medical records were collected from two centers from patients who presented to the emergency department (ED) for GI bleeding and received 4F-PCC or plasma for VKA reversal between January 2015 and December 2020. ED, hospital, intensive care unit (ICU) length of stay (LOS) …

Expanding The Dimensionality Of Team Deviance: An Organizing Framework And Review, Trevor Spoelma, Tamanna Chauhan

Faculty and Staff Publications

Although team deviance is known to detract from team functioning, extant literature largely focuses on deviance that is independently enacted and directed internally toward other members. This relatively narrow focus poses limitations to the practical application of strategies to reduce the incidence and negative impact of team deviance. We offer a four-dimensional typology that takes into account features of team deviance that are important yet undertheorized: level of coordination and target membership. We use this typology to summarize current research, highlight the narratives on team deviance that underlie each dimension, and discuss how to advance the research domain.