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Voices From The Jicarilla Apache: A Critical Analysis On The Impact Of Colonization, Assimilation, On Language Loss Across Generations, Haeyalyn R. Muniz Apr 2022

Voices From The Jicarilla Apache: A Critical Analysis On The Impact Of Colonization, Assimilation, On Language Loss Across Generations, Haeyalyn R. Muniz

Teacher Education, Educational Leadership & Policy ETDs

The purpose of this study was to provide a critical analysis of the impact of colonization and assimilation on the Jicarilla Apache Language through narratives across generations. From a narrative inquiry perspective, I aimed to provide personal stories from among the Jicarilla Apache about language learning environments, experiences, and perspectives. Participants shared those used in the context of everyday interaction which provided language learning and transmission, impact of assimilation policies and practices from residential schools, historical intergenerational trauma, loss of language resulting in loss of culture and ceremonies, transmission of language, and an understanding of collective ideas for additional efforts …


Buying Goodwill: Local And Regional Consumer Relationships In Nineteenth Century New Mexico, Erin Nicole Hegberg Apr 2022

Buying Goodwill: Local And Regional Consumer Relationships In Nineteenth Century New Mexico, Erin Nicole Hegberg

Anthropology ETDs

This dissertation uses comparative analysis of four nineteenth century Hispanic sites to examine the daily practices by Hispanic residents of acquiring and consuming material goods (1821–1912). Through the practice of consumption, Hispanics created and reinforced social relationships with the groups who bartered or sold them goods. In frontier New Mexico consumer relationships reflected important networks that may have played a role in the creation and maintenance of modern Hispanic identity after U.S. annexation. The nineteenth century was a key moment in the developing racialization of Hispanic identity in New Mexico, which makes it a vital period of study for archaeologists …


Investigation Of Iron Homeostasis In Colon Tumorigenesis, Hyeoncheol Kim Ph.D. Apr 2022

Investigation Of Iron Homeostasis In Colon Tumorigenesis, Hyeoncheol Kim Ph.D.

Chemistry and Chemical Biology ETDs

Iron is essential part of the human metabolism. It is a catalytic co-factor for many proteins, but it generates harmful reactive oxygen species in human body. Also, many irons metabolic genes are changes in human cancer cells compared to normal cells, leading to iron accumulation in cancer cells especially in colorectal cancer.

Due to iron’s significant role in colorectal cancer promotion, much research is focused on its role in colorectal cancer genesis. But some important metabolic aspects are not fully addressed and researched. One key aspect of iron on colorectal cancer cell progression is hemin iron. Much research warned hemin …


The 5th Humor, Stella Maria Perry Apr 2022

The 5th Humor, Stella Maria Perry

Theatre & Dance ETDs

I will be using a self-interview as a method of investigating both the origins of myself, the artist, and the work produced I have produced in and out of the MFA Dramatic Writing program with a special focus on my dissertation play, The Blood Vessel.

The intention is to investigate how my plays have come into existence and how they inform each other. This is done through a series of questions I ask myself under the pseudonym Penelope Hawkins. Penelope guides me through the investigation as a character, thus becoming part of the work of the self-interview and still …


Regulation Of Refining And Marketing (The "Downstream" Sector), Joseph A. Schremmer Apr 2022

Regulation Of Refining And Marketing (The "Downstream" Sector), Joseph A. Schremmer

Faculty Book Display Case

The table of contents, indices, and list of authorities is available for this treatise.

NEW: Chapter 29: Oil and Gas – Regulation of the oil and gas industry under federal, state, tribal, and local law, including intersections with the major environmental statutes


Against Political Speech, John M. Kang Apr 2022

Against Political Speech, John M. Kang

Faculty Scholarship

The Supreme Court has dedicated itself to the proposition that political speech, more than any other category of speech, is deserving of the highest protection. A succession of cases amply supports this proposition. In Virginia v. Black, the Court announced that "lawful political speech [is] at the core of what the First Amendment is designed to protect." The Court similarly declared in Monitor Patriot Co. v. Roy that the First Amendment "has its fullest and most urgent application" to political speech. In McIntyre v. Ohio Elections Commission, the Court held that "handing out leaflets in the advocacy of …


Sprinting A Marathon: Next Steps For Gender Equity In Criminal Law Employment, Maryam Ahranjani Apr 2022

Sprinting A Marathon: Next Steps For Gender Equity In Criminal Law Employment, Maryam Ahranjani

Faculty Scholarship

In an era when women’s hard-fought and hard-earned participation in the workforce is in peril, the ABA Criminal Justice Section’s Women in Criminal Justice Task Force (TF) continues its groundbreaking work of documenting challenges in hiring, retention, and promotion of women criminal lawyers. Sprinting a Marathon follows up on the initial findings of the TF as published in the Berkeley Journal of Criminal Law and the ABA Criminal Justice magazine and on the ABA Criminal Justice Section website. This Article describes the results of a survey of diverse criminal lawyers and judges conducted at the end of 2020, as well …


3d Library From Body Size From Unconventional Specimens: A 3d Geometric Morphometrics Approach To Fishes From Ancestral Pueblo Contexts, Jonathan Dombrosky, Thomas F. Turner, Alexandra Harris, Emily Lena Jones Apr 2022

3d Library From Body Size From Unconventional Specimens: A 3d Geometric Morphometrics Approach To Fishes From Ancestral Pueblo Contexts, Jonathan Dombrosky, Thomas F. Turner, Alexandra Harris, Emily Lena Jones

Anthropology Faculty & Staff Publications

Animal body size estimation from zooarchaeological specimens often relies on specific, one-dimensional (i.e., conventional) measures from skeletal elements. Here, we introduce an animal body size estimation technique for archaeological fishes that relies on 3D reference scans and the calculation of centroid size, a standard 3D geometric morphometric proxy measure for organism size. Centroid size-based estimations on whole caudal vertebrae are strongly correlated with a widely accepted measure (i.e., centrum width), but the scalability and flexibility of the centroid size-based approach allows for use on a wide variety of fragmented remains. We use zooarchaeological fish remains (subfamily Ictiobinae) from late pre-Hispanic …


Nm Stat § 7-36-20: Disconnected Land And Water Policy In A Climate-Altered Peri-Urban Fringe, Annalise Porter Apr 2022

Nm Stat § 7-36-20: Disconnected Land And Water Policy In A Climate-Altered Peri-Urban Fringe, Annalise Porter

Water Resources Professional Project Reports

New Mexico (NM) passed a land use law in 1967 that offers tax subsidies to agricultural landowners and is implemented at the county level. This law illustrates a stark disconnect between land and water policy: there are water policy implications because of it, but it has never been discussed accordingly. With a focus on New Mexico’s primary urban county, this study estimates that in 2020, Rio Grande surface flows were used to irrigate 4,388 acres of Bernalillo County land that received the special tax valuation offered through the law. This represents a potential use of nearly 11,000 acre-feet of water, …


Community School Implementation, Melanie Blea Apr 2022

Community School Implementation, Melanie Blea

Teacher Education, Educational Leadership & Policy ETDs

A community school model is one way that struggling schools can restructure under the 2015 Every Student Succeeds Act. Schools operate under the idea that the needs of the whole child must be met before academic advancement can begin. Implementation of a community school model includes obtaining feedback from all stakeholder groups in a school community (students, staff, parents, and community organizations) and examining data to make collective decisions that generate shared responsibility and accountability. The four pillars of a community school (integrated student supports, expanded learning time and opportunities, family and community engagement, and collaborative leadership and practices) …


Gathering Around A New Fire: The Bemo Family, Interracial Marriage, Race, And Power In The Mvskoke Nation, 1870-1897, Michelle M. Martin Mar 2022

Gathering Around A New Fire: The Bemo Family, Interracial Marriage, Race, And Power In The Mvskoke Nation, 1870-1897, Michelle M. Martin

History ETDs

“Gathering Around a New Fire: The Bemo Family, Interracial Marriage, Race, and Power in the Mvskoke Nation, 1870-1897” explores from an Indigenous and gendered perspective the lived experiences of the interracial Bemo family in the Mvskoke Nation located in the Indian Territory (now Oklahoma). The marriage of Douglas Bemo, a Mvskoke/Semvnole student at Tullahassee Mission, to Katie Edwards, his white teacher, is the primary focus of this dissertation. My research seeks to restore Indigenous cultural agency to the complex Bemo family history. I merge Katie’s myopic narrative, federal Indian policy documents, missionary records, and nineteenth-century newspapers with Mvskoke/Semvnole oral histories, …


Hydrocortisone To Improve Survival Without Bronchopulmonary Dysplasia, Kristi L. Watterberg, Michele C. Walsh, Lei Li, Sanjay Chawla, Carl T. D'Angio, Ronald N Goldberg, Susan R. Hintz, Matthew M Laughon, Bradley A. Yoder, Kathleen A. Kennedy, Georgia E. Mcdavid, Conra Backstrom-Lacy, Abhik Das, Margaret M. Crawford, Martin Keszler, Gregory M. Sokol, Brenda B. Poindexter, Namasivayam Ambalavanan, Anna Maria Hibbs, William E. Truog, Barbara Schmidt, Myra H. Wyckoff, Amir M. Khan, Meena Garg, Patricia R. Chess, Anne M. Reynolds, Mohannad Moallem, Edward F. Bell, Lauritz R. Meyer, Ravi M. Patel, Krisa P. Van Meurs, C Michael Cotten, Elisabeth C. Mcgowan, Abbey C. Hines, Stephanie Merhar, Myriam Peralta-Carcelen, Deanne E. Wilson-Costello, Howard W. Kilbride, Sara B. Demauro, Roy J. Heyne, Ricardo A. Mosquera, Girija Natarajan, Isabell B. Purdy, Jean R. Lowe, Nathalie L. Maitre, Heidi M. Harmon, Laurie A. Hogden, Ira Adams-Chapman, Sarah Winter, William F. Malcolm, Rosemary D. Higgins, Eunice Kennedy Shriver Nichd Neonatal Research Network Mar 2022

Hydrocortisone To Improve Survival Without Bronchopulmonary Dysplasia, Kristi L. Watterberg, Michele C. Walsh, Lei Li, Sanjay Chawla, Carl T. D'Angio, Ronald N Goldberg, Susan R. Hintz, Matthew M Laughon, Bradley A. Yoder, Kathleen A. Kennedy, Georgia E. Mcdavid, Conra Backstrom-Lacy, Abhik Das, Margaret M. Crawford, Martin Keszler, Gregory M. Sokol, Brenda B. Poindexter, Namasivayam Ambalavanan, Anna Maria Hibbs, William E. Truog, Barbara Schmidt, Myra H. Wyckoff, Amir M. Khan, Meena Garg, Patricia R. Chess, Anne M. Reynolds, Mohannad Moallem, Edward F. Bell, Lauritz R. Meyer, Ravi M. Patel, Krisa P. Van Meurs, C Michael Cotten, Elisabeth C. Mcgowan, Abbey C. Hines, Stephanie Merhar, Myriam Peralta-Carcelen, Deanne E. Wilson-Costello, Howard W. Kilbride, Sara B. Demauro, Roy J. Heyne, Ricardo A. Mosquera, Girija Natarajan, Isabell B. Purdy, Jean R. Lowe, Nathalie L. Maitre, Heidi M. Harmon, Laurie A. Hogden, Ira Adams-Chapman, Sarah Winter, William F. Malcolm, Rosemary D. Higgins, Eunice Kennedy Shriver Nichd Neonatal Research Network

Pediatrics Research and Scholarship

BACKGROUND: Bronchopulmonary dysplasia is a prevalent complication after extremely preterm birth. Inflammation with mechanical ventilation may contribute to its development. Whether hydrocortisone treatment after the second postnatal week can improve survival without bronchopulmonary dysplasia and without adverse neurodevelopmental effects is unknown.

METHODS: We conducted a trial involving infants who had a gestational age of less than 30 weeks and who had been intubated for at least 7 days at 14 to 28 days. Infants were randomly assigned to receive either hydrocortisone (4 mg per kilogram of body weight per day tapered over a period of 10 days) or placebo. Mandatory …


20220321_Meet Our Students Monday- Six Month Shout-Out, Varina Kosovich Mar 2022

20220321_Meet Our Students Monday- Six Month Shout-Out, Varina Kosovich

HSLIC Blog Post

No abstract provided.


Surviving The Field: Providing The Bare Minimum For Farmworkers In New Mexico, Annie Swift Mar 2022

Surviving The Field: Providing The Bare Minimum For Farmworkers In New Mexico, Annie Swift

New Mexico Law Review

People have cultivated the land now known as New Mexico for millennia. Throughout the last century, however, state law has denied important protections to agricultural workers and thereby contributed to the creation of an agrarian working class that is especially vulnerable to political majorities and powerful interests. For example, the New Mexico legislature explicitly exempted certain farm workers from the Workers’ Compensation Act in 1937, and from the Minimum Wage Act in 1966. Nationally, farm workers have faced exclusion from various labor, health, and safety laws. Consequently, farm workers have enjoyed few legal safeguards against the risk of injury and …


Presas Efímeras Of New Mexico, José A. Rivera Ph.D. Mar 2022

Presas Efímeras Of New Mexico, José A. Rivera Ph.D.

Faculty Publications

The main title of this paper mimics a groundbreaking investigation by anthropologist Teresa Rojas Rabiela and ethnohistorian Ignacio Gutiérrez Ruvalcaba titled: Las presas efímeras mexicanas, del pasado y del presente (Ephemeral diversion dams of Mexico, past and present). Their study inspired the addition of counterpart cases from Nuevo México, a former Mexican province directly north of the Juarez-El Paso border. The work here describes the traditional dams of the northern Río Grande region and also serves as a guide to future research and the development of historic preservation projects. After introducing readers to Las presas efímeras mexicanas, …


Wagon Tracks Volume 36, Issue 2 (January 2022) Feb 2022

Wagon Tracks Volume 36, Issue 2 (January 2022)

Wagon Tracks

Contents

2 On the Cover: The Trail to Santa Fe by Ron Kil Logo Design by Sultan Sultan

4 Introduction

5 Beyond New Mexico and Missouri: Diverse People and Places of the SFT by Guy McClellan

6 What Can the Trail Teach Us? by Steve Schmidt

7 International Connections of the Santa Fe Trail Map by Dr. Susan Calafate Boyle

8-16 The Santa Fe Trail and National Expansion: Commerce, Conquest, and Commemoration by Dr. Leo Oliva

17-23 Business, Politics, and Power: The Transcontinental World of Bent, St. Vrain and Company 1829-1849 by Dr. David C. Beyreis

23 Media Coverage of …


Non-Autophagy Role Of Atg5 And Nbr1 In Unconventional Secretion Of Il-12 Prevents Gut Dysbiosis And Inflammation, Seth D. Merkley, Samuel M. Goodfellow, Yan Guo, Zoe E R Wilton, Janie R. Byrum, Kurt C. Schwalm, Darrell L. Dinwiddie, Rama R. Gullapalli, Vojo Deretic, Anthony Jimenez Hernandez, Steven B. Bradfute, Julie G. In, Eliseo F. Castillo Feb 2022

Non-Autophagy Role Of Atg5 And Nbr1 In Unconventional Secretion Of Il-12 Prevents Gut Dysbiosis And Inflammation, Seth D. Merkley, Samuel M. Goodfellow, Yan Guo, Zoe E R Wilton, Janie R. Byrum, Kurt C. Schwalm, Darrell L. Dinwiddie, Rama R. Gullapalli, Vojo Deretic, Anthony Jimenez Hernandez, Steven B. Bradfute, Julie G. In, Eliseo F. Castillo

Pediatrics Research and Scholarship

Intestinal myeloid cells play a critical role in balancing intestinal homeostasis and inflammation. Here, we report that expression of the autophagy-related 5 [Atg5] protein in myeloid cells prevents dysbiosis and excessive intestinal inflammation by limiting IL-12 production. Mice with a selective genetic deletion of Atg5 in myeloid cells [Atg5ΔMye] showed signs of dysbiosis preceding colitis, and exhibited severe intestinal inflammation upon colitis induction that was characterised by increased IFNγ production. The exacerbated colitis was linked to excess IL-12 secretion from Atg5-deficient myeloid cells and gut dysbiosis. Restoration of the intestinal microbiota or genetic deletion of IL-12 in Atg5ΔMye mice attenuated …


Long-Term Monitoring And Maintenance Plan For The Mixed Waste Landfill - March 2012, Revision I February 16, 2022, Sandia National Laboratories/Nm Feb 2022

Long-Term Monitoring And Maintenance Plan For The Mixed Waste Landfill - March 2012, Revision I February 16, 2022, Sandia National Laboratories/Nm

Facilities-Units

This Revision I_February 16, 2022 version of the Long-term Monitoring and Maintenance Plan for the Mixed Waste Landfill replaces the original March, 2012 MWL LTMMP.


Telafer University’S Experiment In E-Learning As Vague Neutrosophic Experiment, Abdul-Aziz A. Aziz, Huda E. Khalid, Ahmed K. Essa Feb 2022

Telafer University’S Experiment In E-Learning As Vague Neutrosophic Experiment, Abdul-Aziz A. Aziz, Huda E. Khalid, Ahmed K. Essa

Neutrosophic Sets and Systems

No abstract provided.


An Intelligent Model To Rank Risks Of Cloud Computing Based On Firm’S Ambidexterity Performance Under Neutrosophic Environment, Mahmoud Ismail, Nayef Alrashidi, Nabil Moustafa Feb 2022

An Intelligent Model To Rank Risks Of Cloud Computing Based On Firm’S Ambidexterity Performance Under Neutrosophic Environment, Mahmoud Ismail, Nayef Alrashidi, Nabil Moustafa

Neutrosophic Sets and Systems

No abstract provided.


Neutrosophic Entropy Based Heavy Metal Contamination Indices For Impact Assessment Of Sarsa River Water Quality Within County Of District Baddi, India, Simerjit Kaur, C. P. Gandhi, Nidhi Singal Feb 2022

Neutrosophic Entropy Based Heavy Metal Contamination Indices For Impact Assessment Of Sarsa River Water Quality Within County Of District Baddi, India, Simerjit Kaur, C. P. Gandhi, Nidhi Singal

Neutrosophic Sets and Systems

No abstract provided.


Blinded Review Of Hippocampal Neuropathology In Sudden Unexplained Death In Childhood Reveals Inconsistent Observations And Similarities To Explained Paediatric Deaths, Dominique F. Leitner, Declan Mcguone, Christopher William, Arline Faustin, Manor Askenazi, Matija Snuderl, Melissa Guzzetta, Heather S. Jarrell, Katherine Maloney, Ross Reichard, Colin Smith, Victor Weedn, Thomas Wisniewski, Laura Gould, Orrin Devinsky Feb 2022

Blinded Review Of Hippocampal Neuropathology In Sudden Unexplained Death In Childhood Reveals Inconsistent Observations And Similarities To Explained Paediatric Deaths, Dominique F. Leitner, Declan Mcguone, Christopher William, Arline Faustin, Manor Askenazi, Matija Snuderl, Melissa Guzzetta, Heather S. Jarrell, Katherine Maloney, Ross Reichard, Colin Smith, Victor Weedn, Thomas Wisniewski, Laura Gould, Orrin Devinsky

Pathology Research and Scholarship

AIMS: Hippocampal findings are implicated in the pathogenesis of sudden unexplained death in childhood (SUDC), although some studies have identified similar findings in sudden explained death in childhood (SEDC) cases. We blindly reviewed hippocampal histology in SUDC and SEDC controls.

METHODS: Hippocampal haematoxylin and eosin (H&E) slides (n = 67; 36 SUDC, 31 controls) from clinical and forensic collaborators were evaluated by nine blinded reviewers: three board-certified forensic pathologists, three neuropathologists and three dual-certified neuropathologists/forensic pathologists.

RESULTS: Among nine reviewers, about 50% of hippocampal sections were rated as abnormal (52.5% SUDC, 53.0% controls), with no difference by cause of death …


Immunogenicity And Protective Capacity Of A Virus-Like Particle Vaccine Against Chlamydia Trachomatis Type 3 Secretion System Tip Protein, Ct584, Everett Webster, Kyra W. Seiger, Susan B. Core, Amanda L. Collar, Hannah Knapp-Broas, June Graham, Muskan Shrestha, Sarah Afzaal, William M. Geisler, Cosette M. Wheeler, Bryce Chackerian, Kathryn M. Frietze, Rebeccah S. Lijek Jan 2022

Immunogenicity And Protective Capacity Of A Virus-Like Particle Vaccine Against Chlamydia Trachomatis Type 3 Secretion System Tip Protein, Ct584, Everett Webster, Kyra W. Seiger, Susan B. Core, Amanda L. Collar, Hannah Knapp-Broas, June Graham, Muskan Shrestha, Sarah Afzaal, William M. Geisler, Cosette M. Wheeler, Bryce Chackerian, Kathryn M. Frietze, Rebeccah S. Lijek

Pathology Research and Scholarship

An effective vaccine against Chlamydia trachomatis is urgently needed as infection rates continue to rise and C. trachomatis causes reproductive morbidity. An obligate intracellular pathogen, C. trachomatis employs a type 3 secretion system (T3SS) for host cell entry. The tip of the injectosome is composed of the protein CT584, which represents a potential target for neutralization with vaccine-induced antibody. Here, we investigate the immunogenicity and efficacy of a vaccine made of CT584 epitopes coupled to a bacteriophage virus-like particle (VLP), a novel platform for Chlamydia vaccines modeled on the success of HPV vaccines. Female mice were immunized intramuscularly, challenged transcervically …


Psychedelic Therapies At The Crossroads Of Trauma And Substance Use: Historical Perspectives And Future Directions, Taking A Lead From New Mexico, Snehal R. Bhatt, Maya Armstrong, Tassy Parker, Marcello Maviglia, Rebecca Kass, Lawrence Leeman, Paul Romo, Douglas Ziedonis Jan 2022

Psychedelic Therapies At The Crossroads Of Trauma And Substance Use: Historical Perspectives And Future Directions, Taking A Lead From New Mexico, Snehal R. Bhatt, Maya Armstrong, Tassy Parker, Marcello Maviglia, Rebecca Kass, Lawrence Leeman, Paul Romo, Douglas Ziedonis

Family and Community Medicine Research and Scholarship

Post-traumatic stress disorder (PTSD), a common condition with potentially devastating individual, family, and societal consequences, is highly associated with substance use disorders (SUDs). The association between PTSD and SUD is complex and may involve adverse childhood experiences (ACEs), historical and multi-generational traumas, and social determinants of health as well as cultural and spiritual contexts. Current psychosocial and pharmacological treatments for PTSD are only modestly effective, and there is a need for more research on therapeutic interventions for co-occurring PTSD and SUD, including whether to provide integrated or sequential treatments. There is a current resurgence of interest in psychedelics as potential …


University Of New Mexico Health Sciences Center Discovery Research Annual Report 2022, Michael Haederle, Sara Mota, El Webb, Chris Corrie, Byron Hughey-Geer, Jett Loe, Sarah Head, Elizabeth Sandlin Jan 2022

University Of New Mexico Health Sciences Center Discovery Research Annual Report 2022, Michael Haederle, Sara Mota, El Webb, Chris Corrie, Byron Hughey-Geer, Jett Loe, Sarah Head, Elizabeth Sandlin

Research Annual Reports

No abstract provided.


Response: Commentary: Evaluating Sensory Integration/Sensory Processing Treatment: Issues And Analysis, Sarah A Schoen, Roseann C Schaaf, Zoe Mailloux, Anita Bundy, Shelly Lane, Teresa A May-Benson, L Diane Parham, Susanne Smith Roley Jan 2022

Response: Commentary: Evaluating Sensory Integration/Sensory Processing Treatment: Issues And Analysis, Sarah A Schoen, Roseann C Schaaf, Zoe Mailloux, Anita Bundy, Shelly Lane, Teresa A May-Benson, L Diane Parham, Susanne Smith Roley

Pediatrics Research and Scholarship

No abstract provided.


Giardial Lipid Rafts Share Virulence Factors With Secreted Vesicles And Participate In Parasitic Infection In Mice, Brian I. Grajeda, Atasi De Chatterjee, Carmen M. Villalobos, Breanna C. Pence, Cameron C. Ellis, Vanessa Enriquez, Sourav Roy, Sukla Roychowdhury, Aaron K. Neumann, Igor C. Almeida, Steven E. Patterson, Siddhartha Das Jan 2022

Giardial Lipid Rafts Share Virulence Factors With Secreted Vesicles And Participate In Parasitic Infection In Mice, Brian I. Grajeda, Atasi De Chatterjee, Carmen M. Villalobos, Breanna C. Pence, Cameron C. Ellis, Vanessa Enriquez, Sourav Roy, Sukla Roychowdhury, Aaron K. Neumann, Igor C. Almeida, Steven E. Patterson, Siddhartha Das

Pathology Research and Scholarship

Giardia lamblia, a protozoan parasite, is a major cause of waterborne infection, worldwide. While the trophozoite form of this parasite induces pathological symptoms in the gut, the cyst form transmits the infection. Since Giardia is a noninvasive parasite, the actual mechanism by which it causes disease remains elusive. We have previously reported that Giardia assembles cholesterol and GM1 glycosphingolipid-enriched lipid rafts (LRs) that participate in encystation and cyst production. To further delineate the role of LRs in pathogenesis, we isolated LRs from Giardia and subjected them to proteomic analysis. Various cellular proteins including potential virulence factors-e.g., giardins, variant surface …


The Giant Axon Of The Squid: A Simple System For Axonal Transport Studies, Joseph A. Degiorgis, Marcus Jang, Elaine L. Bearer Jan 2022

The Giant Axon Of The Squid: A Simple System For Axonal Transport Studies, Joseph A. Degiorgis, Marcus Jang, Elaine L. Bearer

Pathology Research and Scholarship

The squid giant axon has a long history of being a superb experimental system in which to investigate a wide range of questions concerning intracellular transport. In this protocol we describe the method used for dissecting the axon to preserve its viability in vitro, and the technique for injecting exogenous materials into the living axon. Now that the squid genome is emerging, and the CRISPR/cas9 system has been successfully applied to knock-out squid genes, the giant axon will resume its place in the scientific pantheon of powerful experimental systems in which to address biological questions pertaining to all eukaryotes.


Reduced Cleavage Of Von Willebrand Factor By Adamts13 Is Associated With Microangiopathic Acute Kidney Injury Following Trauma, William E. Plautz, Shannon H. Haldeman, Mitchell R. Dyer, Jason L. Sperry, Francis X. Guyette, Patricia A. Loughran, Jurgis Alvikas, Adnan Hassoune, Lara Hoteit, Nijmeh Alsaadi, Brian S. Zuckerbraun, Marian A. Rollins-Raval, Jay S. Raval, Roberto I. Mota, Matthew D. Neal Jan 2022

Reduced Cleavage Of Von Willebrand Factor By Adamts13 Is Associated With Microangiopathic Acute Kidney Injury Following Trauma, William E. Plautz, Shannon H. Haldeman, Mitchell R. Dyer, Jason L. Sperry, Francis X. Guyette, Patricia A. Loughran, Jurgis Alvikas, Adnan Hassoune, Lara Hoteit, Nijmeh Alsaadi, Brian S. Zuckerbraun, Marian A. Rollins-Raval, Jay S. Raval, Roberto I. Mota, Matthew D. Neal

Pathology Research and Scholarship

Acute kidney injury (AKI) is common after trauma, but contributory factors are incompletely understood. Increases in plasma von Willebrand Factor (vWF) with concurrent decreases in ADAMTS13 are associated with renal microvascular thrombosis in other disease states, but similar findings have not been shown in trauma. We hypothesized that molecular changes in circulating vWF and ADAMTS13 promote AKI following traumatic injury. VWF antigen, vWF multimer composition and ADAMTS13 levels were compared in plasma samples from 16 trauma patients with and without trauma-induced AKI, obtained from the Prehospital Air Medical Plasma (PAMPer) biorepository. Renal histopathology and function, vWF and ADAMTS13 levels were …


From Logic To Realism To Brighter Future For Humanity, Victor Christianto, Florentin Smarandache Jan 2022

From Logic To Realism To Brighter Future For Humanity, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This collection of published papers at International Journal of Neutrosophic Science actually began with just a simple request by Dr. Broumi Said, the editor of IJNS, to us, to submit an article for his new journal. Then we submitted a series of new articles discussing various applications of Neutrosophic Logic, a new kind of logic as developed by one of us (FS). We explore a wide range of subject, from Godel’s incompleteness theorem, to possible technocalypse and neutro-futurology, and also additional sections. Hopefully you will find these articles interesting for better understanding of nature.