Digital Commons Network^™

The Effect Of Sublingual Testosterone On Ischemic Pain Sensitivity, Chance Strenth

Psychology ETDs

Sex differences in pain have been reported for over a half-century with males having higher pain tolerance and lower pain sensitivity than females. Testosterone, a male hormone, is associated with pain perception in humans. However, as of yet no study has directly manipulated a participants’ testosterone to test for causal relationship between testosterone and pain. A double-blind fully-crossed study was conducted using sublingual administration of 0.5 mg testosterone. Twenty female participants completed two 5-hour sessions over a 3-day period. Participants completed an ischemic pain task, behavioral tasks and self-report measures at baseline and at post-administration to explore the effects of …

Factors That Determine Spreading Depolarization Propagation In Brain Slices, Linday Selters

Biomedical Engineering ETDs

In the US alone, more than 750,000 people had a stroke in 2017, more than 1.7 million reported a traumatic brain injury, and more than 9 million suffered from migraines with aura. While all three of these neurological conditions have vastly different causes and possible outcomes they all have a common phenomenon occurring within the brain. A wave that slowly propagates through grey matter, hitting neurons with a large burst of energy, opening them up to a flood of ions and silencing them for an extended period of time. These waves are known as spreading depolarizations (SD). Within well-nourished tissue, …

Fresa Style In Mexico: Sociolinguistic Stereotypes And The Variability Of Social Meanings, Rebeca Martinez Gomez

Linguistics ETDs

This dissertation examines the flexibility in the social meanings of sociolinguistic stereotypes and how linguistic and non-linguistic information affect these meanings. The investigation consists of four empirical studies surrounding the case of fresas in Mexico –members of the upper class that are perceived as using a unique linguistic style.

Study 1 investigates the linguistic and non-linguistic characteristics associated with the fresa stereotype. Through a qualitative analysis of 64 webpages and 3 performances of the style, it is shown that fresasare perceived as the counterpart of another construct, nacos,and that their linguistic style is linked to English due to …

Seasonal Shifts In C3 And C4 Resource Use By A Small Mammal Community Under Changing Precipitation Regimes, Alaina Dianne Pershall

Biology ETDs

In light of climate change and projections of increasing temperatures and aridity in the North American southwest, it is essential to understand how consumer populations will respond to changes in the resource landscape. Rainfall varies in timing and intensity and therefore the timing, proportion, phenology, and abundance of C₃ and C₄ plant resources vary seasonally and annually. Here we examine rodent resource use in the Chihuahuan desert and focus on two distinct precipitation pulses in this system, where spring C₃ plants increase production in response to winter rains and C₄ plants respond to summer monsoons. We …

Evaluating The Aryl Hydrocarbon Receptor As A Target For Pharmacologic Activity Of Repurposed Drugs, Teofilo Borunda Duque

Pharmaceutical Sciences ETDs

The discovery of new pharmacologic targets is important for the advancement of pharmacotherapy and identification of new indications for current drugs. The aryl hydrocarbon receptor (AHR) is a physiologic sensor of both chemical environmental pollutants and ligands of natural origin. Given the broad spectrum of ligands that activate the AHR and its relationship with toxicology, the AHR is not thought to be a traditional target for pharmacotherapy. However, multiple studies have shown potential for the AHR as a novel pharmacologic target Therefore, identifying less toxic agents that modulate the AHR may elucidate mechanisms for pharmacological targeting of the AHR. The …

Using Δ13c, Δ15n, And Δ2h To Better Understand The Ecology Of Green Sea Turtles, Laura Pagès Barceló

Biology ETDs

Many green sea turtle populations are slowly recuperating from a recent severe decline due to anthropogenic factors including human consumption and mortality related to the fishing industry. Despite being charismatic animals that have been extensively studied, there is still a limited understanding of their feeding strategies and diet plasticity. This research explores the use of hydrogen isotopes in marine ecosystems to better understand green sea turtle ecology. This study is presented in two chapters: I first examined the trophic discrimination factor (D²H_NET) for hydrogen isotope (d²H) as a tool to correct hydrogen isotope data …

Water Quality Assessment In The Santa Fe River: Tracking Pollution Sources Via Quantitative Polymerase Chain Reaction Analysis, Hayley Aurora Hajic

Geography ETDs

Microbial contamination affects many water bodies in the United States and pathogens associated with contamination pose a threat to human health. While the nation’s lakes, streams and rivers have been monitored for decades, many still do not meet the requirements of the 1972 Clean Water Act. Due to the number of pathogens that occur in water bodies, it is not feasible to directly monitor all of them. Instead of testing for a plethora of pathogens, it is standard practice for water divisions to monitor fecal indicator bacteria (FIB) as a proxy to determine water quality. There are significant flaws, however, …

Women Near Tv's White House: Power, Gender, And Race On Us Narrative Television, Teresa Caprioglio

Foreign Languages & Literatures ETDs

CBS’s drama Madam Secretary, USA’s miniseries Political Animals, and ABC’s drama Scandal all debuted between 2012-14, each with a female protagonist working closely with the executive branch in Washington-based political circles. Each displays, however, a different engagement with political activity and its relationship to personal life and relationships and to personal identity and presentation. By examining the configurations of gender and power in Madam Secretary and Political Animals, both of which portray female Secretaries of State, this thesis addresses the visual and behavioral expectations for TV women’s access to power and visibility as women and political actors, …

The Heart Of K'É: Transforming Diné Special Education And Unsettling The Colonial Logics Of Disability, Sandra Yellowhorse

American Studies ETDs

This paper takes up the roles of ideology and spatiality as they impact Diné students and learners in understanding conceptions of normativity, neuro-diversity and bodily variance. I am concerned with how the movement and creation of Indigenous schools and their praxis still maintain and often times produce settler colonial ideologies of being, personhood, difference and ability. I illustrate the challenges that Diné planners and educators face in entrenching cultural knowledge and language into their educational initiatives, while some of the problematic manifestations and expressions of normativity present themselves through state polices, federal law and mainstream curriculum.

I focus on the …

Development Of A Positron-Emitting Surrogate Microsphere For Image-Based Dosimetry In Yttrium-90 Radioembolization Therapy, Gregory D. Chambers

Nuclear Engineering ETDs

Radioembolization of liver tumors using yttrium-90 (Y-90) labeled microspheres is a proven method of treatment. The primary decay mode of Y-90 is beta-minus decay. The electrons produced during decay deliver a cytotoxic radiation dose in a localized volume. The radiation dose is sufficient to kill tumor cells yet spare the normal liver. The Y-90 microspheres are delivered via a catheter that has been placed in an artery that supplies blood to the tumor. Microspheres are injected and the blood distributes the microspheres. The current practice involves two separate procedures. The first procedure is an assessment of the vasculature of the …

Fight The “Sitting Disease” – Walk With Your Community, University Of New Mexico Prevention Research Center

Events

Join the Edgewood community and UNM medical student Shana Drake-Levelle for a walk near the Edgewood soccer fields.

Moderate Prenatal Alcohol Exposure Impairs Performance In An Object-Place-Paired-Associate Task, Lilliana May Sanchez

Psychology ETDs

Memory impairments, including spatial and object processing, are often observed in individuals with Fetal Alcohol Spectrum Disorder. Much attention has been directed towards the hippocampus, which displays significant alterations after moderate prenatal alcohol exposure (PAE). In the present study, we tested a moderate PAE rat model in an object-place-paired-associate (OPPA) task, previously shown to require hippocampal processing. The OPPA task was composed of training rats to discriminate between an identical pair of objects presented in 180° opposite arms of a radial arm maze. Animals were given a total of 10 trials per day over 14 consecutive days of training and …

Learning To Read In The Theaetetus: The Recuperation Of Writing In Plato's Philosophy, Luke Lea

Foreign Languages & Literatures ETDs

In my thesis, I take up the popular question of the status of writing in Plato’s dialogues, but from a fresh perspective. Instead of approaching the question of writing head-on, I attend to the philosophical message about reading presented by two dialogues, the Phaedrus and the Theaetetus. My thesis offers interpretations of two individual dialogues whose emphasis on writing and reading as both literary themes and philosophical problems ensure that the overall meanings of these dialogues cannot be reached without attention to this subject.

Although I examine the dialogues in isolation, believing that the setting and characters unique to …

Violence Against Journalists Persists In Mexico, Carlos Navarro

SourceMex

No abstract provided.

Environmentalists Warn About Further Drop In Numbers Of Endangered Porpoises In Mexico, Carlos Navarro

SourceMex

No abstract provided.

Knowledge Sharing As A Means For Capacity Building In International Non-Governmental Organizations In Ecuador, Yolanda E. Ledesma Silva

Latin American Studies ETDs

The purpose of this research was to study factors that facilitate technical knowledge sharing internally in international non-governmental organizations (INGOs) in Ecuador. Using a qualitative design, and semi-structured interviews this study examined knowledge sharing practices in four INGOS located in Quito, capital of Ecuador.

The findings supported nine factors identified in the literature as influencing knowledge sharing practices. These factors included (1) organizational culture, (2) role in organization, (3) procedures for managing knowledge, (4) perceived value of knowledge sharing, (5) media used for sharing information, (6) management practices, (7) organizational structure, (8) mission and strategy, and (9) organizational climate and …

Racial Condition Of America Through ‘Uncle Tom’S Cabin’, Ellerie Ann Freisinger

2018 Award Winners

No abstract provided.

Remark On Vacuum Fluctuation As The Cause Of Universe Creation: Or How Neutrosophic Logic And Material Point Method May Resolve Dispute On The Origin Of The Universe Through Re-Reading Gen. 1:1-2, Florentin Smarandache, Victor Christianto

Branch Mathematics and Statistics Faculty and Staff Publications

Questions regarding the formation of the Universe and what was there before the existence of Early Universe have been great interest to mankind of all times. In recent decades, the Big Bang as described by the Lambda CDMStandard Model Cosmology has become widely accepted by majority of physics and cosmology communities. Among other things, we can cite A.A. Grib Pavlov who pointed out some problems of heavy particles creation out of vacuum and also other proposal of Creatio ex nihilo theory (CET). But the philosophical problems remain, as Vaas pointed out: Did the universe have a beginning or does it …

Grains By Bill Winders (Polity Press, 240 Pages; 2017), Sabina Gaynor

Natural Resources Journal

No abstract provided.

Human Rights And The Global Climate Change Regime, Atieno Mboya Samandari

Natural Resources Journal

This article discusses human rights implications of the market-based mechanisms operationalized under the global climate change regime. It examines greenhouse gas emissions rights created by the Kyoto Protocol and continued by the Paris Agreement. This article discusses implications of these rights for the protection and realization of human rights in the wake of climate change and argues that greenhouse gas emissions rights, as currently constituted, are incompatible with human rights protections. While the Paris Agreement’s recognition of human rights is a significant development, the protection and realization of human rights by states under a free-market approach to climate change remains …

A Lot To Digest: Advancing Food Waste Policy In The United States, Alexandra Evans, Robin Nagele

Natural Resources Journal

An estimated thirty-one percent of the food grown, produced, and transported in the United States is wasted annually. This waste translates into ninety-six billion pounds of food and $165 billion in lost economic value. Food waste occurs at all phases of the supply chain, stretching from farm to table, and imposes substantial economic, environmental, and social costs. This Article highlights the staggering quantity of food waste in the United States and argues that certain innovative policies and market-based initiatives that strategically target the most egregious and unjustifiable types of food waste can efficiently reduce this problem. Applying a simple cost-benefit …

Physical And Chemical Interactions Affecting U And V Transport From Mine Wastes, Sumant Avasarala

Civil Engineering ETDs

This research investigates the physical and chemical interactions that affect the transport of uranium (U) and vanadium (V) from uranium mine waste sites by integrating laboratory experiments and reactive transport modelling with various spectroscopy, microscopy, and diffraction techniques. The document consists of results from three related studies. In the first study (Chapter 3), the reactive transport of U and V was investigated by sequentially reacting mine wastes collected from Blue Gap/Tachee Claim-28 mine site, AZ with 10mM NaHCO₃ (7.9) and 10mM CH₃COOH (3.4) during continuous flow through column experiments. Under both of these conditions (pH 3.4 and …

The Long-Term Effect Of Erythropoiesis Stimulating Agents Given To Preterm Infants: A Proton Magnetic Resonance Spectroscopy Study On Neurometabolites In Early Childhood, Charles Gasparovic, Arvind Caprihan, Ronald A Yeo, John Phillips, Jean R Lowe, Richard Campbell, Robin K Ohls

Pediatrics Research and Scholarship

BACKGROUND: Erythropoiesis stimulating agents (ESAs) are neuroprotective in cell and animal models of preterm birth. Prematurity has been shown to alter neurometabolite levels in children in studies using proton magnetic resonance spectroscopy (1H-MRS).

OBJECTIVE: We hypothesized that ESA treatment in premature infants would tend to normalize neurometabolites by 4-6 years of age.

MATERIALS AND METHODS: Children in a longitudinal study of neurodevelopment underwent MRI and 1H-MRS at approximately 4 years and 6 years of age. Prematurely born children (500-1,250 g birth weight) received ESAs (erythropoietin or darbepoetin) or placebo during their neonatal hospitalization, and these groups were compared to healthy …

Global Seawater Redox Trends During The Late Devonian Mass Extinction Detected Using U Isotopes Of Marine Carbonates, David Allen White

Earth and Planetary Sciences ETDs

The Late Devonian extinction ranks as one of the ‘big five’ Phanerozoic extinctions affecting up to 80% of marine species and occurred during five distinct pulses spanning /or widespread marine anoxia. We test the marine anoxia hypothesis by analyzing uranium isotopes (δ²³⁸U) across a ~7 My interval of well-dated Upper Devonian marine carbonates from the Devil’s Gate Limestone in Nevada, USA.

The measured δ²³⁸U curve shows no co-variation with local anoxic facies, water-depth dependent facies changes, redox-sensitive metals, TOC, or diagnostic elemental ratios indicating the δ²³⁸U curve was not controlled by local depositional or …

Thinking Out Loud On Primeval Atom, Big Bang & Biblical Account Of Creation, Florentin Smarandache, Victor Christianto

Branch Mathematics and Statistics Faculty and Staff Publications

In recent years, the Big Bang as described by the Lambda CDM-Standard Model Cosmology has become widely accepted by majority of physics and cosmology communities. Some people even have concluded that it has no serious alternative in horizon. Is that true? First, as we argued elsewhere, Big Bang relies on singularity, so, when we are able to describe the observed data without invoking singularity, then Big Bang model is no longer required. In this paper, we explore a few alternatives other than Big Bang which most cosmologists believe is the closest to biblical account of creation. We argue that re-reading …

Costa Rica, Panama, Ecuador Launch Initiative To Fight Organized Crime In The Pacific, George Rodrã­Guez

NotiCen

No abstract provided.

Impact Of Drought On Land Cover Changes In Diné Bikéyah – A Study Through Remote Sensing, Anjanette A.J. Hawk

Geography ETDs

This study identifies land cover changes associated with a ten-year drought period and discusses the importance of vegetation change in Diné Bikéyah, a semi-arid land located in a remote part of the southwestern United States (US). This study concludes that drought produced slight changes in vegetation within a 540 km² study area in the Tselani-Cottonwood Chapter (TCC) in Diné Bikéyah. The data for this study consist of three Landsat images for the years 1998, 2002, and 2009. The methods used to analyze these Landsat images included image pre-processing, calculation of normalized difference vegetation index (NDVI) images, and supervised (maximum …

Mathematical Modeling Of Nanoparticle Biodistribution, Prashant Dogra

Biomedical Sciences ETDs

The prospects of nanoparticle-based drug delivery and imaging have been hindered by insufficient understanding of the effects of nanoparticle physicochemical properties on their in vivo disposition. Here, we present an integrative mathematical modeling and in vivo imaging approach to quantify the relationship between nanoparticle physicochemical properties, namely, size, surface charge, and surface chemistry, on their in vivo disposition kinetics in healthy rats. We developed simple master equations in closed-form to accurately represent the time-dependent concentration of nanoparticles in different regions of the body and obtain functional relationships for predictive purpose to support rational design of nanomedicine. We further used …

Thinking Out Loud On Early Creation Through The Lens Of Hermeneutics Of Sherlock Holmes (Towards A Model Of Universe Based On Turbulence-Generated Sound Theory), Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In recent years, apparently the Big Bang as described by the Lambda CDM-Standard Model Cosmology has become widely accepted by majority of physics and cosmology communities. Even some people have concluded that it has no serious alternative in horizon. Is that true? First, as we argued elsewhere, Big Bang story relies on singularity. In other words, when we are able to describe the observed data without invoking singularity, then Big Bang model is no longer required. Therefore, here we explore a few alternative stories other than Big Bang story, which most cosmologists believe it is the nearest to Biblical account …

Regent Policy Manual, Board Of Regents

UNM HLC 2018-19 Assurance Argument Evidence

The Regents Policy Manual as it was constituted in 2018. This manual provides a fundamental grounding to the total governance of the university insofar as it guides the actions and policies of the Board of Regents, and in this, charges various other bodies within the university with governance responsibilities, e.g. section 5.1 which defines the faculty's role in the university's academic mission. Other notable sections includes the institutional polices on "Diversity and Campus Climate" (section 2.4), and "Hiring, Promotion, and Transfer" (6.2).