Digital Commons Network^™

The Role Of Tax Incentives On Business Location And Economic Growth, Sadie Xi Rose Mazzola

Honors Theses and Capstones

No abstract provided.

An In-Depth Analysis Of The Data Analytics Job Market, Dagny Elaine Wilkins

Honors Theses and Capstones

No abstract provided.

Covid-19’S Impact On Human Trafficking: The Invisible Industry In New Hampshire, Brittany Dunkle

Honors Theses and Capstones

Human trafficking is a modern-day form of slavery that operates on the premise of exploitation, such as forced prostitution and labor, and organ trafficking. This is a global industry resulting in billions. Despite the current global pandemic, COVID-19, putting a halt to many livelihoods around the world, human trafficking will persist, but in conditions that are potentially more harmful for the victims. Victims of trafficking are in an increasingly vulnerable position, and it is important to establish possible mechanisms to protect as many victims and potential victims as possible. Typical risk factors (i.e., poverty, state’s interest vs. individual interest, unemployment) …

Roles Of Non-Frankia Bacteria In Root Nodule Formation And Function In Alnus Sp., Kelsey Christine Mercurio

Honors Theses and Capstones

Plant roots are home to a wide variety of beneficial microbes; understanding and optimizing plant-microbe interactions may be critical to enhance global food security in a sustainable, equitable way. With the help of their nitrogen-fixing bacterial partner, Frankia, actinorhizal plants form symbiotic root nodules and play important roles in agroforestry and land reclamation. However, Frankia does not live alone in nodules, and the other microbial residents may contribute to nodule formation and function. We collected root nodules from alder trees (Alnus sp.) in 2018 and 2019, then isolated DNA and individual bacterial strains to characterize the nodule microbial …

Mimicking The Effect Of Prolactin On Stat3/Stat5 Activity In Breast Cancer, Jennifer N. Barbuto, Sarah R. Walker

Honors Theses and Capstones

Signal transducers and activators of transcription (STAT) 3 and 5 are commonly constitutively activated in breast cancer. STAT5 can outcompete STAT3 and reduce cell proliferation and metastasis. STAT5 activation is stimulated by prolactin, a natural hormone that can be harmful at high levels. The aim of this study is to identify some possible previously developed drugs that mimic the effect of prolactin and STAT5 without the added risk in MDA-MB231 breast cancer cells. Using the CLUE database query app and STAT5 up- and downregulation signatures, three drugs (X, K, and M) were chosen based on their similarity in signatures to …

An Analysis Of River Channel Change Over Time In The Lamprey River, Trevor R. Fenoff

Honors Theses and Capstones

Flooding causes river channel change that threatens people and property. Due to climate change and urbanization, flooding events are projected to happen more frequently in the future, which will make the associated hazards worse. This project estimated the historical river channel change in the Lamprey River in southern New Hampshire. River channel change was estimated by delineating riverbank location on historical aerial photographs. The river channel change was compared to river width, curvature, and the number of 1.5-year flood events to explore the drivers of river channel change in the Lamprey River.

Corticostriatal Pathway Inactivation And Connections To Associative Learning With Nicotine Stimulus In Rats, Anna Kalinowski

Honors Theses and Capstones

The main concern of this study is looking into the neural mechanisms of associative learning with a nicotine stimulus. The goal of this study was to find out if inactivating the corticostriatal pathway through DREADDs (Designer Receptors Exclusively Activated by Designer Drugs) inhibited goal-tracking behavior in rats. In this experiment, rats underwent two surgeries. One was to inject DREADDs into the infralimbic cortex and the other in the dorsomedial caudate-putamen (dmCPu). Rats were initially trained on levers through water deprivation. Once they reached the criterion, they moved on to the self-administration phase. After the rats were trained in self-administration sessions …

Sars-Cov-2: An Investigation On Mutagenicity And Its Effects On Infectivity And Mortality, Tyler Elliott Silverwood

Honors Theses and Capstones

SARS-CoV-2, the etiological agent of the COVID-19 pandemic, has rapidly become a worldwide public health concern. Classified as a betacoronavirus, it is the third human coronavirus (HCoV) to emerge in the 21st century that causes severe disease, alongside SARS-CoV and MERS-CoV. The genome consists of open reading frames encoding accessory proteins and four structural proteins, including the spike protein which is a key determinant of host cell tropism. Mutations within the genome, particularly the spike gene, have been linked in-vitro to increased binding affinity to the human receptor angiotensin-converting enzyme 2 (hACE2), increased fitness in human hosts, and immune evasion. …

Multimedia Of The Mind: Digital Rhetoric And Interdisciplinary Acquisition, Parker C. Ayotte

Honors Theses and Capstones

Multimodal digital narratives are currently in the spotlight for acquisition into the digital humanities. The narrative form is emerging with great research interest, the form having no previously established traditions. This research paper attempts to define the nature of multimodal digital narratives and their implementation into modern society. Specifically, the paper addresses the digital rhetoric appropriated by multimodal digital narratives and how it translates into modifying perceptions of society. This multimodal digital rhetoric is then explored in the context of digital activism and education, formative social discourses the augment societal perceptions. Digital rhetoric is utilized to augment a user’s reality …

Occurrence Of Pulmonary Arteritis With Lungworm Infections In Gray Seals From New England, 2013-2020, Jillian R. Broadhurst, Inga Sidor Dvm, Ms, Dacvp

Honors Theses and Capstones

Gray seals (Halichoerus grypus) are a common pinniped species in New England coastal waters. Parasitic infection is an important cause of mortality for this species, and lungworm species are frequently implicated in cases of respiratory infection, especially in pups and weanling seals. The most common of these is Otostrongylus circumlitus, a large nematode found in the bronchi and bronchioles of affected seals. The full life cycle is unknown but its presence in lungs and sometimes pulmonary arteries suggests that migration via arterial circulation occurs. Signs and microscopic findings are widely variable; our cases included dyspnea, bloody mucoid …

Scottish Marine Renewable Energy: U.S. Approaches For Development Of Wave And Tidal Technologies, Stella Kathryn Fairall

Honors Theses and Capstones

Marine renewable energy, energy harnessed from various ocean resources such as waves, tides, currents, thermal gradients, and marine streams, has incredible potential in the United States. Several European countries have realized the potential of the resource in the North Sea and Atlantic and have created incredibly successful industries already. The United Kingdom, particularly Scotland, is the world leader because of the comprehensive policy, labor force, and markets it has established in order to make MRE a competitive energy source. In the United States, the industry is immature, underfunded, and lacks policy support. In order to establish itself as a world …

New Hampshire Continental Shelf Historical Geophysical Database: 1971 To 2015 - Sediment Data, Larry G. Ward, Rachel C. Morrison, Zachary S. Mcavoy, Maxlimer Coromoto Vallee-Anziani

Data Catalog

The UNH CCOM/JHC "New Hampshire Continental Shelf Historical Geophysical Database: 1971 to 2015 - Sediment Data" contains sediment grain size data and classifications from studies conducted between 1971 and 2015. In total, grain size data was available for 725 bottom sediment samples. Included are sample identification information, station and sample characteristics, sediment classifications, grain size statistics, and grain size distribution. Not all of these parameters were available for every study. Samples were analyzed with standard sieve and pipette analyses after Folk (1980). The sediment grain size classifications include: CMECS (Coastal and Marine Ecological Classification Standard; FGDC, 2012); Gradistat (Blot and …

Goose Pond 2021 Water Quality Highlight Report, Amanda Mcquaid, Robert Craycraft

UNH Cooperative Extension

A Water Quality Highlight Report by UNH CE Lakes Lay Monitoring Program for Goose Pond in Caanaan and Hanover, NH (Deep Station) in 2021.

Wakondah Pond 2021 Water Quality Highlight Report, Amanda Mcquaid, Robert Craycraft

UNH Cooperative Extension

A Water Quality Highlight Report by UNH CE Lakes Lay Monitoring Program for Wakondah Pond in Moultonboro, NH in 2021.

New Hampshire Continental Shelf Geophysical Database: Vibracore Logs And Sediment Data, Larry G. Ward, Rachel C. Morrison, Zachary S. Mcavoy, Maxlimer Coromoto Vallee-Anziani

Data Catalog

The "New Hampshire Continental Shelf Geophysical Database: Vibracore Logs and Sediment Data" contains complete core logs and sediment grain size data from twenty‐three vibracores taken on the New Hampshire shelf in 1984 and 1988. During the present program, the original core descriptions, data, and photographs were verified and significantly expanded, synthesized, and presented in uniform core logs.The vibracore logs, sediment data, and the depositional environments are discussed in detail in Ward et al., 2021 (https://dx.doi.org/10.34051/p/2021.26).

New Hampshire Continental Shelf Geophysical Database: 2016-2017 Field Campaign – Seafloor Photographs, Larry G. Ward, Rachel C. Morrison, Zachary S. Mcavoy

Data Catalog

The "New Hampshire Continental Shelf Geophysical Database: 2016-2017 Field Campaign – Seafloor Photographs” was developed by the University of New Hampshire (UNH) Center for Coastal and Ocean Mapping/Joint Hydrographic Center (CCOM/JHC). The field campaign was conducted to provide ground truth for surficial geology maps for the continental shelf off New Hampshire (NH) and focused on the inner shelf between the coast and the Isles of Shoals. Station locations were chosen where high-resolution bathymetry was available, including multibeam echosounder (MBES) surveys conducted by the UNH CCOM/JHC Hydrographic Field Course (Ocean Engineering 972), MBES surveys by the NOAA National Ocean Service (NOS), …

Improving Employee Engagement On An Inpatient Unit: A Quality Improvement Project, Holly Mccormack

DNP Scholarly Projects

BACKGROUND: Engaged employees are paramount to the success of an organization. They are more invested in their organization and the unit on which they work. This investment in the organization results in higher patient satisfaction and safety, less staff turnover, and improved quality. According to the literature, generational differences may be necessary to consider when improving employee engagement. To successfully lead a multigenerational workforce, nurse leaders should consider these differences and incorporate them into their strategic plan for employee engagement.

METHODS: A pilot survey was conducted on a medical-surgical unit to assess a perceived lack of engagement. Subsequently, work engagement …

Improving The Diagnosis Of Major Depression In A Primary Care Practice Using The Patient Health-9 Questionnaire, Chukwudi C. Orji

DNP Scholarly Projects

Abstract

Background: Major depression is a serious health problem that affects both children and adults. It is a leading cause of disability worldwide. Most cases of major depression are treated in primary care settings. Many cases of major depression presenting in primary care are missed. Many PCPs do not routinely use screening tools. The aim of this project is to improve the diagnosis of major depression in adults in a primary care practice through routine use of the Patient Health Questionnaire-9 (PHQ-9) during initial encounter with patients and during follow-up visit for patients who are receiving treatment for depression to …

Use Of A Simplified Protocol For The Prevention Of Postoperative Nausea And Vomiting In Adult Ambulatory Surgical Patients, Roger Horne

DNP Scholarly Projects

Postoperative nausea and vomiting (PONV) remains a common complication affecting surgical patients after receiving anesthesia. Prevention of PONV is important in an ambulatory surgical setting where patient access to rescue treatment is limited after discharge. A quality improvement (QI) project introduced a simplified PONV prevention strategy to decrease the incidence of PONV at a Veterans Health Administration ambulatory surgery center. A retrospective chart audit of all facility surgical patients receiving anesthesia care (n = 94), excluding ophthalmology patients, was conducted prior to COVID-19 restrictions to establish baseline PONV incidence. An evidence-based, simplified PONV prevention protocol was developed and implemented. …

Improving Care Transitions For Individuals With Suicide Risk After Discharged From Acute Unit, Maureen Ndu

DNP Scholarly Projects

Background: Suicide is a public health problem and the 10th leading cause of death in the US. Suicide accounted for more than 47,5000 deaths in the US in 2017, translating to about 130 suicide deaths each day. An average of 20 veterans commits suicide each day compared to 93 suicides in the general population in the US. Individuals with suicide risks are 300 times at an increased rate of suicide death in the first week and 200 times in the first month of hospital discharge. Nurses are in a strategic position to improve the care transition of individuals with suicide …

Using A Psychopharmacology Education Program To Increase Primary Care Provider Comfort With Treating Basic Psychiatric Disorders, Latesha Reed

DNP Scholarly Projects

BACKGROUND: Almost 1 in 5 people have been diagnosed with a mental health illness but the supply of psychiatric providers does not meet patient’s needs. Multiple reasons contribute to this shortage and nurse practitioners are part of the solution. Even with nurse practitioners specializing in psychiatric mental health there is still a shortage. Primary care is where most patients first present their mental health issues.

METHODS: Literature review informed the development of the educational intervention presented to the primary care providers using a digital, asynchronous learning format. A gap analysis of organizational needs and weaknesses was used to determine the …

Unh 4-H Scholarship Program, Landau

UNH Cooperative Extension

No abstract provided.

Factor Fiction? Identifying A Putative Toxoplasma Gondii Transcriptional Complex, Julia M. Paquette

Honors Theses and Capstones

Toxoplasma gondii is a highly prevalent protozoan parasite that is estimated to infect 30-50% of the global population, though there is no treatment for chronic infection and current treatments for acute infection may have serious side effects. Transcription is a tightly regulated process in T. gondii, allowing the parasite to successfully invade and replicate within host cells, and it is thus a promising avenue to study gene regulation and to investigate possible novel therapeutics. In our lab’s previous research, a TFIID-like complex was identified in T. gondii and found to be associated with the parasite specific bromodomain protein BDP3. …

Presidents And The U.S. Constitution: The Executive’S Role In Interpreting The Supreme Law Of The Land, Mitchell Scacchi

Honors Theses and Capstones

In 1832, President Andrew Jackson issued a veto message claiming the same duty as the Supreme Court to interpret the U.S. Constitution. Do modern presidents exercise the principal role in interpreting the U.S. Constitution that President Jackson claimed was their duty, and, if so, in what ways do they choose to articulate their interpretations? The hypothesis is that modern presidents have exercised a principal role in interpreting the U.S. Constitution similar to the interpretative duty expressed by President Jackson, and they perform this duty, in part, through the issuance of veto messages and signing statements. After a content analysis of …

Individualized Coaching To Improve Pre-School Quality: Perception Of Teachers And Administrators, Danielle Anna Picot

Honors Theses and Capstones

No abstract provided.

Impact Of An Educational Module On Female Collegiate Athlete Knowledge Regarding The Female Athlete Triad, Cayla Marie Barretto

Honors Theses and Capstones

The Female Athlete Triad was defined in women’s sport as early as 1992, by the American College of Sports Medicine (ACSM). The guidelines regarding the Triad emphasis the importance of education in the prevention of the disorder. However, there is little research supporting if this education is occurring and if it is effective. A quantitative, quasi-experimental study was conducted at the University of New Hampshire. Twenty-five female collegiate athletes participated in a pre-test, educational intervention, and post-test to determine baseline knowledge and if there was any improvement in knowledge after education. Percent changes in scores from pre-test and post-test were …

The Future Of Auditing: An Analysis Of Ai Implementation In The Big Four Accounting Firms, Alexander Michael Heye

Honors Theses and Capstones

The implementation of Artificial Intelligence (AI) technology has become somewhat of a hot topic within the modern business world. Many companies have chosen to embrace the potential that these systems have on the ways we can conduct business, while others are hesitant to “dip their toes” in the figurative waters of AI research and utilization. Auditing is no different from other industries in that firms are excited to see what potential these new innovations have in store for promoting a faster, more efficient, and more accurate audit. This review peers into how some Big 4 firms have made the first …

Does The Emigration Of Skilled Labor From Hungary Merit Being Called A Brain Drain?, Alexa Marie Mayo

Honors Theses and Capstones

No abstract provided.

A Critical Review Of Apraxia Of Speech And Childhood Apraxia Of Speech, Madison Joan Smith

Honors Theses and Capstones

The theories and neural bases of Apraxia of Speech (AOS) have long been debated. In 1861, Paul Broca identified two patients with speech/language impairments who became the basis for the theory on aphemia, now known as apraxia. Broca noted of patients with AOS that “there are cases in which the general faculty for language remains unaltered; where the auditory apparatus is intact; where all muscles—including those of speech and articulation—are under voluntary control; and where nevertheless, a cerebral lesion abolishes articulated language” (Broca, 1861/2000). The term “apraxia” was first introduced by Hugo Liepmann in 1908 and was described as “the …

Changing Representations Of The Second World War: Why We Fight, Victory At Sea, And The World At War, Maiah Vorce

Honors Theses and Capstones

No abstract provided.