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Articles 2761 - 2790 of 17691
Full-Text Articles in Entire DC Network
Complete Genome Sequences Of Cluster A6 And Cluster G1 Mycobacterium Smegmatis Phages Hoot And Jolene, Jon Thompson, Asli Özdemir, Arsen M. Topchyan, Maxwell Torosian, Victoria Z. Thymianos, Angelica Eagle, Juliana Mccormick, Leon Kyle G. Boyles, Azucena A. Benito, Kurt Regner, Christy Strong, Philippos K. Tsourkas
Complete Genome Sequences Of Cluster A6 And Cluster G1 Mycobacterium Smegmatis Phages Hoot And Jolene, Jon Thompson, Asli Özdemir, Arsen M. Topchyan, Maxwell Torosian, Victoria Z. Thymianos, Angelica Eagle, Juliana Mccormick, Leon Kyle G. Boyles, Azucena A. Benito, Kurt Regner, Christy Strong, Philippos K. Tsourkas
Life Sciences Faculty Research
We present the complete genome sequences of Mycobacterium smegmatis phages Hoot and Jolene, isolated in Las Vegas, NV. The phages were isolated and annotated by students enrolled in an undergraduate research course at the University of Nevada, Las Vegas. Hoot is a cluster A6 mycobacteriophage, while Jolene is in cluster G1.
Effects Of Cyproheptadine On Body Weight Gain In Children With Nonorganic Failure To Thrive In Taiwan: A Hospital-Based Retrospective Study, Yi-Chun Lin, Hung-Rong Yen, Fuu-Jen Tsai, Chung-Hsing Wang, Lung-Chang Chien, An-Chyi Chen, Ro-Ting Lin
Effects Of Cyproheptadine On Body Weight Gain In Children With Nonorganic Failure To Thrive In Taiwan: A Hospital-Based Retrospective Study, Yi-Chun Lin, Hung-Rong Yen, Fuu-Jen Tsai, Chung-Hsing Wang, Lung-Chang Chien, An-Chyi Chen, Ro-Ting Lin
Epidemiology & Biostatistics Faculty Research
Failure to thrive (FTT) impairs the expected normal physical growth of children. This study aimed to evaluate the effects of cyproheptadine hydrochloride on growth parameters in prepubertal children with FTT. The medical records of prepubertal children who were newly diagnosed with FTT at China Medical University Hospital between 2007 and 2016 were retrospectively examined. The patients were divided into two groups depending on whether they had (T-group) or had not (NT-group) received cyproheptadine hydrochloride (0.3 mg/kg daily) for at least 14 days. The mean length of the treatment period was 97.22 days (range: 14–532 days). Weight, height, and body mass …
International Sex Survey: Study Protocol Of A Large, Cross-Cultural Collaborative Study In 45 Countries, Beata Bothe, Monika Koos, Lena Nagy, Shane W. Kraus, Marc N. Potenza, Zsolt Demetrovics
International Sex Survey: Study Protocol Of A Large, Cross-Cultural Collaborative Study In 45 Countries, Beata Bothe, Monika Koos, Lena Nagy, Shane W. Kraus, Marc N. Potenza, Zsolt Demetrovics
Psychology Faculty Research
Background and aims: Limitations of research into sexuality and compulsive sexual behavior disorder (CSBD) include the use of simplistic methodological designs and the absence of quality and unified measurements, empirically supported theoretical models, and large, collaborative studies between laboratories. We aim to fill these gaps with the International Sex Survey (ISS, http://internationalsexsurvey.org/). Methods: The ISS is a large-scale, international, multi-lab, multi-language study using cross-sectional survey methods, involving more than 40 countries. Participants responding to advertisements complete a self-report, anonymous survey on a secure online platform. Collaborators from each country collect a community sample of adults with a minimum sample size …
Multi-Messenger Astrophysics With Theseus In The 2030s, Bing Zhang, Numerous Authors, See Full List Below
Multi-Messenger Astrophysics With Theseus In The 2030s, Bing Zhang, Numerous Authors, See Full List Below
Physics & Astronomy Faculty Research
Multi-messenger astrophysics is becoming a major avenue to explore the Universe, with the potential to span a vast range of redshifts. The growing synergies between different probes is opening new frontiers, which promise profound insights into several aspects of fundamental physics and cosmology. In this context, THESEUS will play a central role during the 2030s in detecting and localizing the electromagnetic counterparts of gravitational wave and neutrino sources that the unprecedented sensitivity of next generation detectors will discover at much higher rates than the present. Here, we review the most important target signals from multi-messenger sources that THESEUS will be …
Sustainable Tourism Empowered By Social Network Analysis To Gain A Competitive Edge At A Historic Site, Cathrine Linnes, Holly Itoga, Jerome Agrusa, Joseph Lema
Sustainable Tourism Empowered By Social Network Analysis To Gain A Competitive Edge At A Historic Site, Cathrine Linnes, Holly Itoga, Jerome Agrusa, Joseph Lema
Hospitality Faculty Research
Social media has had a strong presence in many people’s lives over the last decade. In addition, social media platforms have allowed people to share opinions, provide advice on numerous factors, including where to visit, as well as to stay connected and maintain friendships. The hospitality and tourism industry, however, can make effective use of these powerful tools for marketing purposes, collaboration and information sharing, and service offerings. Reviewing social media followers’ behaviors and interests offers a wealth of information and valuable data for a variety of tourism organizations. This case study focuses on an analysis of the social networks …
Population Growth In Mountain West Cities And Suburbs, 2010-2020, Dielle T. Telada, William E. Brown Jr.
Population Growth In Mountain West Cities And Suburbs, 2010-2020, Dielle T. Telada, William E. Brown Jr.
Cities & Metros
COVID-19 altered population growth trends within large cities and the relative growth of cities and suburbs within the nation’s largest metropolitan areas. Brookings senior fellow William H. Frey suggests “that most big cities with populations exceeding 250,000 experienced lower population growth in the year the pandemic began than in the previous year.” This Fact Sheet examines annual growth rates within selected Mountain West metros and suburbs from 2010 and 2020.
A Protocol And Novel Tool For Systematically Reviewing The Effects Of Mindful Walking On Mental And Cardiovascular Health, Dustin W. Davis, Bryson Carrier, Brenna Barrios, Kyle Cruz, James W. Navalta
A Protocol And Novel Tool For Systematically Reviewing The Effects Of Mindful Walking On Mental And Cardiovascular Health, Dustin W. Davis, Bryson Carrier, Brenna Barrios, Kyle Cruz, James W. Navalta
Kinesiology and Nutrition Sciences Faculty Research
To our knowledge, no published systematic review has described the effects of mindful walking on mental and cardiovascular health. We have aimed to fill this gap by first establishing our systematic review protocol. Our protocol was adapted from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and is registered in PROSPERO (Registration Number: CRD42021241180). The protocol is described step-by-step in this paper, which we wrote to achieve three objectives: to adhere to the best practices stated in the PRISMA guidelines, to ensure procedural transparency, and to enable readers to co-opt our protocol for future systematic reviews on mindful …
Unlv Top Tier Focus - Student Achievement, University Of Nevada, Las Vegas
Unlv Top Tier Focus - Student Achievement, University Of Nevada, Las Vegas
Focus on Top Tier 2.0
Our Student Achievement goal involves student success, which includes retention and graduation rates, but also includes other academic needs, services, and co-curricular learning experiences. As we evolve to Top Tier 2.0, we will continue with our focus on undergraduate student success and expand to include graduate and professional student opportunities, as well as career development and progression as we work to graduate students who are career ready.
Cognitive Effects Of The Bet Protein Inhibitor Apabetalone: A Prespecified Montreal Cognitive Assessment Analysis Nested In The Betonmace Randomized Controlled Trial, Jeffrey Cummings, Gregory G. Schwartz, Stephen J. Nicholls, Aziz Khan, Chris Halliday, Peter P. Toth, Michael Sweeney, Jan O. Johansson, Norman C.W. Wong, Ewelina Kulikowski, Kamyar Kalantar-Zadeh, Kenneth Lebioda, Henry N. Ginsberg, Bengt Winblad, Henrik Zetterberg, Kausik K. Ray
Cognitive Effects Of The Bet Protein Inhibitor Apabetalone: A Prespecified Montreal Cognitive Assessment Analysis Nested In The Betonmace Randomized Controlled Trial, Jeffrey Cummings, Gregory G. Schwartz, Stephen J. Nicholls, Aziz Khan, Chris Halliday, Peter P. Toth, Michael Sweeney, Jan O. Johansson, Norman C.W. Wong, Ewelina Kulikowski, Kamyar Kalantar-Zadeh, Kenneth Lebioda, Henry N. Ginsberg, Bengt Winblad, Henrik Zetterberg, Kausik K. Ray
School of Medicine Faculty Research
Background: Epigenetic changes may contribute importantly to cognitive decline in late life including Alzheimer's disease (AD) and vascular dementia (VaD). Bromodomain and extra-terminal (BET) proteins are epigenetic 'readers' that may distort normal gene expression and contribute to chronic disorders. Objective: To assess the effects of apabetalone, a small molecule BET protein inhibitor, on cognitive performance of patients 70 years or older participating in a randomized trial of patients at high risk for major cardiovascular events (MACE). Methods: The Montreal Cognitive Assessment (MoCA) was performed on all patients 70 years or older at the time of randomization. 464 participants were randomized …
Re-Thinking Women's Sport Research: Looking In The Mirror And Reflecting Forward, Katie Lebel, Ceyda Mumcu, Ann Pegoraro, Nicole M. Lavoi, Nancy Lough, Dunja Antunovic
Re-Thinking Women's Sport Research: Looking In The Mirror And Reflecting Forward, Katie Lebel, Ceyda Mumcu, Ann Pegoraro, Nicole M. Lavoi, Nancy Lough, Dunja Antunovic
Educational Psychology, Leadership, and Higher Education Faculty Research
Despite decades of research and advocacy—women's professional sports continue to be considered second class to men's sports. The goal of this paper is to rethink how we state, present, and solve problems in women's sport. To affect true change, the wisdom of a broad stakeholder group was embraced such that varied perspectives could be considered. A three-question survey was developed to examine what key constituents believe is working in women's sports, what they believe the salient challenges are for women's sport, and how they would prioritize the next steps forward in the post-pandemic sport landscape. Results indicated siloed differences of …
Perceptions Of Dental Undergraduates Towards Online Education During Covid-19: Assessment From India, Nepal And Sri Lanka, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, Rajlakshmi Banerjee, Rasika Manori Jayasinghe, Dhanushka Leuke Bandara, Navin Agrawal, Vimmi Singh
Perceptions Of Dental Undergraduates Towards Online Education During Covid-19: Assessment From India, Nepal And Sri Lanka, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, Rajlakshmi Banerjee, Rasika Manori Jayasinghe, Dhanushka Leuke Bandara, Navin Agrawal, Vimmi Singh
School of Medicine Faculty Research
Purpose: The social distancing mandates instituted during COVID-19 pandemic mark the sudden transition in the mode of dental education’s delivery to the virtual instruction. It is vital to assess students’ perceptions towards virtual learning environments, particularly among those gaining education in resource-strained countries. This cross-sectional study aims to assess the perceptions of dental undergraduates towards online education, environment and transferable skills and patient care during COVID-19 in India, Nepal, and Sri Lanka. Materials and Methods: Dental preclinical and clinical undergraduate students from India, Nepal and Sri Lanka were recruited from November 2020 to March 2021 through a 47-item web-based survey …
Artificial Image Objects For Classification Of Breast Cancer Biomarkers With Transcriptome Sequencing Data And Convolutional Neural Network Algorithms, Xiangning Chen, Daniel G. Chen, Zhongming Zhao, Justin M. Balko, Jingchun Chen
Artificial Image Objects For Classification Of Breast Cancer Biomarkers With Transcriptome Sequencing Data And Convolutional Neural Network Algorithms, Xiangning Chen, Daniel G. Chen, Zhongming Zhao, Justin M. Balko, Jingchun Chen
School of Medicine Faculty Research
Background: Transcriptome sequencing has been broadly available in clinical studies. However, it remains a challenge to utilize these data effectively for clinical applications due to the high dimension of the data and the highly correlated expression between individual genes. Methods: We proposed a method to transform RNA sequencing data into artificial image objects (AIOs) and applied convolutional neural network (CNN) algorithms to classify these AIOs. With the AIO technique, we considered each gene as a pixel in an image and its expression level as pixel intensity. Using the GSE96058 (n = 2976), GSE81538 (n = 405), and GSE163882 (n = …
Testing Multi-Theory Model (Mtm) In Explaining Sunscreen Use Among Florida Residents: An Integrative Approach For Sun Protection, Manoj Sharma, Matthew Asare, Erin Largo-Wight, Julie Merten, Mike Binder, Ram Lakhan, Kavita Batra
Testing Multi-Theory Model (Mtm) In Explaining Sunscreen Use Among Florida Residents: An Integrative Approach For Sun Protection, Manoj Sharma, Matthew Asare, Erin Largo-Wight, Julie Merten, Mike Binder, Ram Lakhan, Kavita Batra
Environmental & Global Health Faculty Research
Florida residents have the second highest incidence of skin cancer in the nation. Sunscreen usage was found to be the one of the most effective integrative health approaches for reducing risk of skin cancer. Given the limited information on the likelihood of adopting and continuing sunscreen usage behavior, this cross-sectional study aimed to examine the correlates of initiating and sustaining sunscreen usage behavior among Florida dwellers, using the fourth-generation, multi-theory model (MTM) of behavior change. A web-based survey containing 51 questions was emailed to Florida residents aged 18 years or above, who were randomly selected from the state voter file. …
Artificial Intelligence (Ai) Capacity In Mountain West Metros, Olivia K. Cheche, Ally M. Beckwith, William E. Brown Jr.
Artificial Intelligence (Ai) Capacity In Mountain West Metros, Olivia K. Cheche, Ally M. Beckwith, William E. Brown Jr.
Economic Development & Workforce
This fact sheet highlights data on artificial intelligence (AI) growth in Mountain West metropolitan areas over the last several decades, as originally reported by Mark Muro and Sifan Liu from the Brookings Institution’s Metropolitan Policy Program. The Brookings report examines how various metros across the United States contribute towards AI technology creation and business activity.
Using Bibliometrics To Evaluate Outcomes And Influence Of Translational Biomedical Research Centers, Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings
Using Bibliometrics To Evaluate Outcomes And Influence Of Translational Biomedical Research Centers, Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings
Educational Psychology, Leadership, and Higher Education Faculty Research
Introduction. Federal grant funding to support infrastructure development of translational biomedical research centers is a form of public health intervention. Establishing rigorous methods for measuring center success and outcomes is essential to justify continued funding. Methods. Bibliometric data compiled from a 5-year funding cycle of a neurodegeneration and translational neuroscience research center was analyzed using the package bibliometrix for open source software R and the NIH-developed research tool iCite. Results. The research team and their collaborators (n=485) produced 157 grant-citing publications from 2015-2020. The science was produced by small research teams clustered around three main communities of topics: Alzheimer's Disease, …
Novel Insights Into Negative Pressure Wound Healing From An In Situ Porcine Perspective, Jacob G. Hodge, Ashley L. Pistorio, Christopher A. Neal, Hongyan Dai, Jennifer G. Nelson-Brantley, Molly E. Steed, Richard A. Korentager, David S. Zamierowski, Adam J. Mellott
Novel Insights Into Negative Pressure Wound Healing From An In Situ Porcine Perspective, Jacob G. Hodge, Ashley L. Pistorio, Christopher A. Neal, Hongyan Dai, Jennifer G. Nelson-Brantley, Molly E. Steed, Richard A. Korentager, David S. Zamierowski, Adam J. Mellott
School of Medicine Faculty Research
Negative pressure wound therapy (NPWT) is used clinically to promote tissue formation and wound closure. In this study, a porcine wound model was used to further investigate the mechanisms as to how NPWT modulates wound healing via utilization of a form of NPWT called the vacuum-assisted closure. To observe the effect of NPWT more accurately, non-NPWT control wounds containing GranuFoam™ dressings, without vacuum exposure, were utilized. In situ histological analysis revealed that NPWT enhanced plasma protein adsorption throughout the GranuFoam™, resulting in increased cellular colonization and tissue ingrowth. Gram staining revealed that NPWT decreased bacterial dissemination to adjacent tissue with …
Pediatrics Hospital Care In China Before And After Policy Change: A Case Study, Donghui Lou, Betty Burston, Guogen Shan, Christopher Cochran, Fuzai Yin, Lianying Wang, Ruiji Liu, Jay J. Shen
Pediatrics Hospital Care In China Before And After Policy Change: A Case Study, Donghui Lou, Betty Burston, Guogen Shan, Christopher Cochran, Fuzai Yin, Lianying Wang, Ruiji Liu, Jay J. Shen
Healthcare Administration and Policy Faculty Research
Worldwide, healthcare policy change ranks among the top three issues in the public’s consciousness. This study introduces a case study of pediatric hospitalizations at one hospital in Northern China. It seeks to assess whether pediatric hospitalization access, costs, and costs structures favorably changed after selected health policy reforms were implemented in China. A census of all hospital pediatric discharge data from 2015 to 2018 were collected from a general public tertiary hospital in Northern China. Using generalized linear regression, changes in charges for length of stay, daily charges, total charges per discharge, and drug charges and medical service fees as …
Hot Spots Policing In Las Vegas: Results From A Blocked Randomized Controlled Trial In Chronic Violent Crime Locations, Nicholas Corsaro, Robin S. Engel, Tamara D. Herold, Murat Yildirim, Ryan T. Motz
Hot Spots Policing In Las Vegas: Results From A Blocked Randomized Controlled Trial In Chronic Violent Crime Locations, Nicholas Corsaro, Robin S. Engel, Tamara D. Herold, Murat Yildirim, Ryan T. Motz
Criminal Justice Faculty Research
Objectives: This randomized experiment explored the impact of hot spots policing (HSP) strategies on criminal offenses and calls for service within chronic, persistent violent crime clusters in Las Vegas, NV. Methods: Forty-four street segments were randomized into treatment (N = 22) and control (N = 22) conditions across nine chronic, persistent violent crime areas. The conditions (foot patrols, stationary patrol vehicles, and business-as-usual) were active for 6 months. Results: Over 90% of the hot spots experienced an average of 1.5 h or greater of patrol dosage per day. In terms of impact, the mixed effects negative binomial regression results showed …
Palliative Care And Life-Sustaining/Local Procedures In Colorectal Cancer In The United States Hospitals: A Ten-Year Perspective, Zahra Mojtahedi, Ja Seol Koo, Ji Yoo, Pearl Kim, Hee-Taik Kang, Jinwook Hwang, Moon Kyung Joo, Jay J. Shen
Palliative Care And Life-Sustaining/Local Procedures In Colorectal Cancer In The United States Hospitals: A Ten-Year Perspective, Zahra Mojtahedi, Ja Seol Koo, Ji Yoo, Pearl Kim, Hee-Taik Kang, Jinwook Hwang, Moon Kyung Joo, Jay J. Shen
School of Medicine Faculty Research
Background: In recent years, palliative care utilization has been increasing while life-sustaining/local procedures have been declining at the end of life. Palliative care utilization widely varies based on tumor type. Limited information is available on inpatient palliative care in colorectal cancer. Aims: This study investigated inpatient palliative care utilization and its association with patient demographics, hospital charges, and procedures among colorectal cancer patients admitted to US hospitals between 2008 and 2017. Receipt of life-sustaining and local procedures and surgeries were also investigated during the ten years. Methods: Data were extracted from the National inpatient sample (NIS) database containing de-identified information …
Covid-19: Tougher On Women?, Aika Dietz
Covid-19: Tougher On Women?, Aika Dietz
Research Briefs
Women are receiving the worst effects of the COVID-19 recession.
Nevada Campaign Financing: U.S. House Of Representatives, 2020, Kristian Thymianos, Olivia K. Cheche, William E. Brown Jr.
Nevada Campaign Financing: U.S. House Of Representatives, 2020, Kristian Thymianos, Olivia K. Cheche, William E. Brown Jr.
Elections & Governance
In the 2020 election cycle, Nevada’s U.S. House of Representatives delegation fundraised a combined total of $9,994,636. This fact sheet summarizes the campaign donations and expenditures of these representatives. The data are collected from the Open Secrets website.
Investment Patterns In Mountain West States, Counties, And Nevada Cities 2005-2019, Peter Grema, Zachary Walusek, Katie M. Gilbertson, William E. Brown Jr.
Investment Patterns In Mountain West States, Counties, And Nevada Cities 2005-2019, Peter Grema, Zachary Walusek, Katie M. Gilbertson, William E. Brown Jr.
Economic Development & Workforce
The purpose of this fact sheet is to summarize findings on capital flows across Mountain West states and counties, and within Nevada cities. The “Gauging Investment Patterns across the US” report by the Urban Institute present findings of overall volume of capital deployed, racial equity of investments, and income equity for each respective geographic area. The full report further breaks down these three main categories into 18 other metrics.
Lobectomy For Acquired Lobar Emphysema Months Following Newborn Repair Of Congenital Diaphragmatic Hernia, Mary Froehlich, Lance Horner, Joseph Stathos, Craig Nakamura, Michael G. Scheidler
Lobectomy For Acquired Lobar Emphysema Months Following Newborn Repair Of Congenital Diaphragmatic Hernia, Mary Froehlich, Lance Horner, Joseph Stathos, Craig Nakamura, Michael G. Scheidler
School of Medicine Faculty Research
Chronic lung disease is a known morbidity of congenital diaphragmatic hernia repair. Although described as a diffuse lung process, we present a case of localized lobar emphysema in a child with a congenital diaphragmatic hernia repair successfully treated with lobectomy. We aim to describe this unique clinical manifestation, detail the intraoperative findings, and describe the successful postoperative course.
Forging Resilience To Hiv/Aids: Personal Strengths Of Middle-Aged And Older Gay, Bisexual, And Other Men Who Have Sex With Men Living With Hiv/Aids, R. Liboro, J. Despres, B. Ranuschio, S. Bell, L. Barnes
Forging Resilience To Hiv/Aids: Personal Strengths Of Middle-Aged And Older Gay, Bisexual, And Other Men Who Have Sex With Men Living With Hiv/Aids, R. Liboro, J. Despres, B. Ranuschio, S. Bell, L. Barnes
Psychology Faculty Research
HIV-positive gay, bisexual, two-spirit, and other men who have sex with men (MSM) have exhibited significant resilience to HIV/AIDS in Canada since the start of the epidemic. Since 2012, most of the research that has been conducted on resilience to HIV/AIDS has utilized quantitative methods and deficits-based approaches, with a preferential focus on the plight of young MSM. In order to address apparent gaps in research on HIV/AIDS resilience, we conducted a community-based participatory research qualitative study that utilized a strengths-based approach to examine the perspectives and lived experiences of HIV-positive, middle-aged and older MSM on their individual attributes that …
Thermal Analysis Of Benzotriazolium Perrhenate And Its Implication To Rhenium Metal, James Louis-Jean, Harry Jang, Andrew J. Swift, Frederic Poineau
Thermal Analysis Of Benzotriazolium Perrhenate And Its Implication To Rhenium Metal, James Louis-Jean, Harry Jang, Andrew J. Swift, Frederic Poineau
Chemistry and Biochemistry Faculty Research
The thermal analysis behavior of C6H6N3[ReO4] was studied by simultaneous thermal gravimetric analysis (TGA) and differential scanning calorimetry (DSC) up to 700 °C under argon. Such analysis afforded rhenium metal, which was characterized by powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), and energy-dispersive X-ray (EDX) spectroscopy. XRD peak broadening due to crystallite size and lattice strain was analyzed by both Williamson-Hall (W-H) and Debye-Scherrer (D-S) methods. Efforts to isolate Re metal from the thermal treatment of benzotriazole (BTA = C6H5N3) with NH4ReO4 and Re2O7 under various atmospheres and temperatures are also reported. The results provide a significant insight into …
Vaccine Hesitancy Within Nevada Counties, June 2021, Kelliann Beavers, Madison Frazee-Bench, William E. Brown Jr.
Vaccine Hesitancy Within Nevada Counties, June 2021, Kelliann Beavers, Madison Frazee-Bench, William E. Brown Jr.
Health
This fact sheet highlights estimated rates of vaccine hesitancy, vaccination rates, the index of social vulnerability, and the level of concern for 17 Nevada counties as of June, 2021. The data are reported in the U.S. Department of Health and Human Services, Assistant Secretary for Planning and Evaluation (ASPE) estimates.
Physical And Mental Disabilities Among The Gender-Diverse Population Using The Behavioral Risk Factor Surveillance System, Brfss (2017–2019): A Propensity-Matched Analysis, Jennifer R. Pharr, Kavita Batra
Physical And Mental Disabilities Among The Gender-Diverse Population Using The Behavioral Risk Factor Surveillance System, Brfss (2017–2019): A Propensity-Matched Analysis, Jennifer R. Pharr, Kavita Batra
Environmental & Global Health Faculty Research
This propensity-matched analysis utilized the publicly available Behavioral Risk Factor Surveillance System (2017–2019) data to compare the burden of disabilities among transgender/non-binary (TGNB) and cisgender groups. The groups were matched (1:1 ratio) on demographic variables using Nearest Neighborhood Matching. Categorical variables were compared among groups using a Chi-square analysis to test differences in the proportions. Multivariate logistic regression analysis was fit to predict the likelihood of the physical and mental disabilities among the TGNB group compared with the cisgender group while controlling for healthcare access factors, income, and employment. Survey weights were included in the model to account for the …
The Costs Of Developing Treatments For Alzheimer’S Disease: A Retrospective Exploration, Jeffrey L. Cummings, Dana P. Goldman, Nicholas R. Simmons-Stern, Eric Ponton
The Costs Of Developing Treatments For Alzheimer’S Disease: A Retrospective Exploration, Jeffrey L. Cummings, Dana P. Goldman, Nicholas R. Simmons-Stern, Eric Ponton
School of Medicine Faculty Research
Introduction: With the exception of the recent accelerated approval of aducanumab, in over 26 years of research and development (R&D) investment in Alzheimer's disease (AD), only five novel drugs—all for symptomatic treatment only—have reached FDA approval. Here, we estimate the costs of AD drug development during this period in the private sector. Methods: To estimate private R&D funding, we collected information on AD clinical trials (n = 1099; phases 1–4) conducted between January 1, 1995 and June 21, 2021 from various databases. Costs were derived using previously published methodologies and adjusted for inflation. Results: Since 1995, cumulative private expenditures on …
A Theory-Based Analysis Of Covid-19 Vaccine Hesitancy Among African Americans In The United States: A Recent Evidence, Manoj Sharma, Kavita Batra, Ravi Batra
A Theory-Based Analysis Of Covid-19 Vaccine Hesitancy Among African Americans In The United States: A Recent Evidence, Manoj Sharma, Kavita Batra, Ravi Batra
Environmental & Global Health Faculty Research
African Americans have been disproportionately vaccinated at lower rates, which warrants the development of theory-based interventions to reduce vaccine hesitancy in this group. The fourth-generation theories, e.g., multi-theory model (MTM) of health behavior change, are vital in developing behavioral interventions. Therefore, the current study aims to determine recent trends in COVID-19 vaccination rates and to test the MTM model in predicting the initiation of COVID-19 vaccines among vaccine-hesitant Blacks. A sample of 428 unvaccinated African Americans were recruited through a web-based survey using a 28-item psychometric valid questionnaire. Chi-square, independent-samples-t-test or Welch’s t test, and Pearson’s correlation tests were utilized …
Cdc Social Vulnerability Index (Svi): Nevada Counties, Vanessa Booth, Ally M. Beckwith, Kelliann Beavers, William E. Brown Jr.
Cdc Social Vulnerability Index (Svi): Nevada Counties, Vanessa Booth, Ally M. Beckwith, Kelliann Beavers, William E. Brown Jr.
Demography
This fact sheet highlights how Nevada counties rank on the Social Vulnerability Index (SVI) as defined by the Center for Disease Control (CDC) and the Agency for Toxic Substances and Disease Registry (ASTDR). Socially vulnerable populations are often disproportionately harmed during public health emergencies such as natural disasters and infectious disease outbreaks. The Geospatial Research, Analysis, and Services Program (GRASP) created the CDC/ATSDR Social Vulnerability Index (CDC/ATSDR SCI) to help public health officials and emergency response planners meet community health needs during response and recovery efforts (ATSDR, 2020).