Digital Commons Network^™

Brain Endothelial Permeability, Transport, And Flow Assessed Over 10 Orders Of Magnitude Using The In Situ Brain Perfusion Technique, Quentin R. Smith, Haritha Mandula, Jagan Mohan R. Parepally, Jun Oki, Fancy Thomas, Helen R. Thorsheim, Abraham J. Al‑Ahmad, Thomas J. Abbruscato, Per Ask, David S. Hage, Peter J. Robinson

David Hage Publications

Background Cerebral blood flow normally places a limit on the magnitude of brain vascular permeability (P) that can be measured in vivo. At normal cerebral blood flow, this limit falls at the lower end of lipophilicity for most FDAapproved CNS drugs. In this study, we report on two methods that can be used to overcome this limitation and measure brain vascular permeability values that are up to ~1000 times higher using the in situ brain perfusion technique.

Methods Rat brain was perfused with physiological saline at increased flow rate and in the presence of various concentrations of plasma protein, serum …

Read More Comics: Developing Student Analysis Skills And Engagement Through The Use Of Comic Books In General Education Courses, Keri Crist-Wagner

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Undergraduate student participation in general education classes constitutes a point of struggle for many educators. Using both critical constructivism and counter storytelling as theoretical frameworks, this multi-method phenomenological case study explored the experiences of undergraduate honors students in a semester-long general education literature class. The purpose of this study was to 1) explore how comics can be used as a pedagogical tool in higher education classrooms, 2) assess the ways in which students interacted with comics, and 3) investigate what role comics played in engagement and development of critical thinking and analysis skills. Primary data collection involved document review of …

The Utilization Of Alcohol Dehydrogenase (Adh) Enzymes In Stereocontrolled Synthesis, Gaurav Pramod Kudalkar

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Clostridium acetobutylicum alcohol dehydrogenase (CaADH) has been shown to catalyze the stereoselective reduction of a broad array of carbonyl compounds. This study uses a Hammett linear free-energy relationship (LFER) analysis to gain insight into CaADH enzyme mechanism across three substrate classes: aryl aldehydes, aryl β-keto esters, and aryl trifluoromethyl ketones. Kinetic data were collected by monitoring NADPH fluorescence, and Michaelis-Menten kinetics were applied. Hammett plots reveal that hydride transfer is rate-limiting for aldehydes and β-keto esters (ρ > 0), while it is proposed that dehydration is rate-limiting for trifluoromethyl ketones (ρ < 0). ¹³C NMR confirmed significant hydration in trifluoromethyl ketones. The …

Minimizing Take Of Threatened Rattlesnakes And Optimizing Project Review In Se Nebraska, Shaun Dunn, Dan Fogell, Colleen Rothe-Groleau

Nebraska Department of Transportation: Research Reports

The western massasauga (Sistrurus tergeminus) and the timber rattlesnake (Crotalus horridus) are protected under Nebraska Statute 37-801-811 and listed as threatened species. These species occur in the right-of-way (ROW) along several roads in Jefferson, Gage, Pawnee, and Richardson Counties which necessitates the need for added Environmental Review (ER) from Nebraska Department of Transportation (NDOT) staff and onsite surveys prior and during maintenance and construction to roadways. This project sought to minimize ER time, staff time, and increase the knowledge of these species in southeast Nebraska by:

1. Identifying precise locations of western massasauga brumation sites;
2. Mapping travel …

Enhancing Water Sustainability In North Africa: Literature Review And Synthesis Of Current Knowledge Gaps In Sudan, Osman M. A. Adam

Department of Agricultural and Biological Systems Engineering: Masters Project Reports

This study delves into the critical role of groundwater in addressing global water challenges, with a focus on the Nubian Sandstone Aquifer System (NSAS) in north Africa. Groundwater constitutes a source of potable water, irrigation, and industrial use, especially in arid regions where surface water is limited. We analyzed the status of water quantity, withdrawals, recharge, and geological characteristics in the NSAS, specifically in Sudan, Egypt, and Libya. Though the NSAS is largely an untapped resource, water withdrawals from the NSAS in Egypt, Sudan, and Libya are projected to increase substantially from 2000 to 2100 due to population growth, with …

Numerical Study On The Behavior Of Natural And Recycled Aggregate Concretes, Shahriar Mardpour

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

This thesis investigates the mechanical behavior of natural and recycled aggregate concretes (NAC and RAC) using a multi-phase numerical approach to predict performance. Growing interest in sustainable materials has led to using recycled concrete aggregates (RCA) to replace natural aggregates, creating Recycled Aggregate Concrete (RAC). Due to their different structural components, RAC and NAC exhibit varying mechanical properties, particularly in strength and durability.

This study validated tension and bending (flexural) test models by comparing numerical results with similar models from the literature. Following validation, a multi-phase approach modeled NAC and RAC for the bending (flexural) and tension tests, providing a …

Understanding And Intervening In Children's Tick Risk Perceptions And Protective Behaviors: A Grounded Theory, Ariel Dawdy

Department of Entomology: Dissertations, Theses, and Student Research

Children, ages 8 years and younger, are at a particularly high risk of contracting a tick-borne disease. This is partially due to the misconceptions spread about tick protective behavior and a poor understanding of how antibiotic treatment can help. Because most communities and families believe that tick control is the individual’s responsibility, looking at the interaction between ticks and human children is essential to understanding the individual’s motivations to protect themselves. To help alleviate the number of individuals contracting tick-borne diseases, misconceptions must be addressed, intervention programs implemented, and a behavioral change must occur. This study used a qualitative research …

Morality, Outgroups, And Politics, John Jostes

Department of Political Science: Dissertations, Theses, and Student Research

Moral differences between Democrats and Republicans contribute to affective polarization, or how negatively each side feels toward one another. Partisans are also generally aware of and sensitive to which social groups comprise the other political party. The present study examines if changes to the United States population, and thus levels of support for the two parties, will influence affective polarization. To do so, participants were randomly assigned to one of two treatment conditions in which they read about demographic changes reported in the 2020 U.S. Census, or a control condition. I find that the treatment conditions did not have a …

Soybean Cyst Nematode (Heterodera Glycines Ichinohe) Virulence Assay Against Resistance Sources In Nebraska, Pratibha Karki

Department of Plant Pathology: Dissertations, Theses, and Student Research

Soybean cyst nematode (SCN, Heterodera glycines Ichinohe), one of the major yield-limiting pathogens of soybean, is currently found in 60 counties of Nebraska that produce more than 90% of the state’s soybean. Often, yield loss occurs without any above-ground symptoms, which makes it difficult to manage. The primary management option is the use of SCN-resistant varieties. Several soybean plant introductions serve as resistance sources against SCN. Unfortunately, the single source, PI 88788, is used in approximately 90% of resistant varieties and its prolonged use has increased the virulence status of SCN in the U.S. A study was conducted to assess …

The Role Of Disgust In Films: Disgust As An Aesthetically Appreciable Emotion That Enhances The Film’S Other Emotional Effects, Yunyi Zhu

Department of Philosophy: Dissertations, Theses, and Student Research

The goal of this paper is to address the questions: what is the role of disgust in films, or what makes people appreciate a film’s disgusting contents, given that disgust is unpleasant to experience? The films to which I am referring are audiovisual artworks, including both TV shows and movies, that arouse the emotion of disgust and typically have contents that are gory or gross, yet despite their disgusting contents, these films have as a primary goal to present a narrative or an experience rather than merely to disgust or disturb their audiences. This includes various genres of films, from …

Controller Software: Evolution, Identification, And Implementation, Balaji Balasubramaniam

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

In the annals of automation history and advancement, one can find control technology is at the core. Modern-day controllers rely heavily on software capability to provide stability and improve the system's performance. In particular, drone flight controllers use autopilot control software to accomplish autonomous navigation from take-off to landing. However, we know very little about how the controller code modifications and its impact, particularly at the software level. No general framework has been developed to identify the control code changes and observe the real values of software control loops at the kernel layer.

In this thesis, we lay the foundation …

Examining Factors Of Variance In Energy Metabolism Of Dairy Cattle, Addison Lee Carroll

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Variation is thought to occur in the use of dietary energy for production in dairy cattle. First, variance can be observed when new methane mitigation strategies are fed resulting in increased H₂ output potentially resulting in downstream effects on estimates heat production via the Brouwer (1965) equation. Therefore, in chapter 3 a review was created to systematically describe the mathematics and theory behind the Brouwer equation, and rederive a heat production equation to integrate H₂ production. Results indicate heat production using the classical Brouwer equation (1965) relative to the rederived equation resulted in an overestimation of heat production …

Mining Work Items To Streamline Software Maintenance Tasks, Salomé Perez-Rosero

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Software engineering maintenance tasks often require associating code changes into groupings of related units of work to have as much information as possible about the developments toward addressing a specific code task. A comprehensive understanding of how a code task has evolved helps developers make better decisions about changes in the overall codebase, where a commit represents the set of code changes made to the codebase at a specific time. While the concept of work items as logically related code changes has been primarily theoretical, its impact on software maintenance tasks, such as tracing the origins of bugs or fixes …

Gamma Sigma Delta, Nebraska Chapter Newsletter, Issue #66 December 2024

Gamma Sigma Delta, Nebraska Chapter: Newsletters

Nominations Solicitations Issue

President's Message, John R. Ruberson

Members

Grad Student Award

Teaching Award

Research Award

Extension Award

Award of Merit

Annual Membership Info

Student Award Fund

In Memoriam: John L. Lambert (April 25, 1942-July 3, 2024), Larry Elmer Germer (April 24, 1941-October 25, 2024), Leo Lucas (1931-November 13, 2024)

Pledge

Examining Factors Of Variance In Energy Metabolism Of Dairy Cattle, Addison L. Carroll

Department of Animal Science: Dissertations, Theses, and Student Research

Variation is thought to occur in the use of dietary energy for production in dairy cattle. First, variance can be observed when new methane mitigation strategies are fed resulting in increased H₂ output potentially resulting in downstream effects on estimates of heat production via the Brouwer (1965) equation. Therefore, in chapter 3 a review was created to systematically describe the mathematics and theory behind the Brouwer equation, and rederive a heat production equation to integrate H₂ production. Results indicate heat production using the classical Brouwer equation (1965) relative to the rederived equation resulted in an overestimation of heat …

“Kematz'ib' Para Gritar” Innovative Technologies In Revitalizing The Mayan Languages: Empowering Youth Through Poetry - A Narrative Study, Héctor De Jesús Palala Martínez

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This dissertation explores innovative approaches to preserving and revitalizing the linguistic and cultural heritage of Mayan-speaking youth of Guatemalan descent in rural Nebraska. It delves into the intersection of technology, artistic expression, and cultural practices, emphasizing the revitalization of Mayan languages in Abya Yala (the Americas), particularly emphasizing the Guatemalan and the Mayan diasporas in Nebraska.

The research investigates the roles of digital humanities, culture-based education, and poetic expressions in language preservation/revitalization efforts among Mayan youth and unaccompanied minors in transnational educational settings. Central to the study is an academic initiative for transnational Mayan high school students integrating poetry and …

Increasing The Impact Of Dietary Fiber From Grains On Human Health Through Gut Microbiome, Sujun Liu

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The relationship between dietary fiber intake and human health has gained significant attention due to its potential in preventing chronic diseases and promoting gut health. Grains are a primary source of dietary fiber; however, the health impact of grain fibers is often limited because they are incompletely metabolized by gut bacteria. This dissertation explores innovative strategies to enhance the concentration and of dietary fiber from grains and its utilization by gut bacteria. By investigating various treatments, this research aims to maximize the health benefits of grain-derived dietary fibers, thereby contributing to a healthier society.

This dissertation is organized into four …

Three New Pieces For Double Bass By Colombian Composers Influenced By Colombian Traditions, Javier Alejandro Barreto Olaya

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This document presents a study on the double bass as a solo instrument within traditional Colombian music, a tradition in which it has generally been relegated to accompaniment functions. I have commissioned three original works by Colombian composers, the integration of traditional genres, including sanjuanero, caña, danza, guabina, and llanero Airs, with modern compositional approaches. The commissioned pieces expand the solo repertoire of the double bass and highlight its potential and ability to adapt to traditional musical contexts. The lack of original repertoire for solo double bass in Colombian music is also addressed, integrating the commissioned pieces. The contribution of …

Domain-Specific Machine Learning Approaches For Geospatial Problems, Shine Bedi

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This dissertation explores novel algorithms for complex geospatial problems at the intersection of environmental, social, and computational sciences. Emphasizing the unique challenges of the geospatial domain, particularly the deviation from the independent and identical distribution (IID) assumption, the research spans various methodologies across different domains, demonstrating the benefits of specialized approaches in spatial analysis.

First, we show that machine learning techniques can be effectively used in environmental modeling, which often has severe class imbalance challenges. Using artificial neural networks (ANN), support vector machines (SVM), and extreme gradient boosting (XGB) and techniques to address class imbalance provides insights into groundwater quality …

Scavenging As An Accelerant In The Postmortem Interval Estimate: Refining Quantitative Regressions For Decomposition Analyses In Southeast Nebraska, Jenna L. Alexander

Department of Anthropology: Theses and Student Research

In forensic anthropology, the postmortem interval (PMI) is an estimation of the time elapsed from the moment of death to the point of discovery or examination. Contemporary approaches for estimating PMI have sought to refine broad quantitative regressions by addressing variance among intrinsic and extrinsic influences of decomposition at a regional level. Southeast Nebraska and the broader Great Plains region encompass one of the most influential agricultural ecosystems, featuring a unique climate type and a diverse spectrum of vertebrate scavengers. While there has been minimal research addressing how the biogeoclimatic conditions of Nebraska affect predicted estimates for PMI using known …

Prevalence Of Autism Spectrum Characteristics In Students Taking Undergraduate Computing Courses, Rachel Michaela Mettenbrink

School of Computing: Dissertations, Theses, and Student Research

The incidence rate of autism spectrum condition (ASC) has increased significantly in recent decades, as awareness of the condition and its impacts increases amongst clinicians, parents, and the general population. Medical literature has proposed that there may be a relationship between ASC and participation in the computing field. This study tests for the prevalence of autism spectrum condition traits measured by delivering the Autism Spectrum Quotient (AQ) to a population of undergraduate computer science students. We examine the relationships between AQ scores and students taking undergraduate computer science classes, sex, socioeconomic status, and parents in the computing industry. Additionally, we …

Exploring Variably Saturated Flow Formulations For Modflow: Implementing A Fully 3d Richards' Equation In Modflow 6, Sebastian Vazquez-Gasty

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

This thesis explores the implementation of a fully 3D Richards’ equation solution into MODFLOW 6 to solve for saturated/unsaturated flow. Currently, MODFLOW 6 has limited capability for solving unsaturated zone flow problems by using the Unsaturated Zone Flow (UZF) package, which neglects capillarity and assumes vertical 1-dimensional flow. Various formulations of the Richards’ equation were first evaluated for their strengths and weaknesses. Various numerical solution approaches to Richards’ equation were also studied to understand the robustness and efficiency of different approaches and to select one that would best fit into the MODFLOW 6 framework. The MODFLOW 6 framework was also …

Acf Response To Ostp Memo, 2022: Public Access Plan (December 2024)

Copyright, Fair Use, Scholarly Communication, etc.

ACF response to OSTP memo, 2022: Public Access Plan (December 2024)

Murdered In Indian Country: Expanding Tribal Criminal Jurisdiction For The Sake Of Indigenous Women, Courtney Shanahan

Nebraska Law Bulletin (Selected Issues)

This paper discusses the Missing and Murdered Indigenous Women Epidemic. Specifically, it analyzes what contributes to the disparate homiciderate for indigenous women by non-Indian offenders in IndianCountry. This paper concludes that to help combat the problem, the federal government should restore tribal criminal jurisdiction over crimes of homicide occurring in Indian Country where the victim is Indian, and the perpetrator is non-Indian.

Part II provides a brief history of colonialism, the use of the Discovery Doctrine in North America, and how the normalization of violence against Native women as a part of “conquest” has led to the violence against Indigenous …

Small Beef-Packer Resilience During The Covid-19 Pandemic: Evidence And Policy Implications, Azzeddine Azzam, Sunil P. Dhoubadel, Binod Khanal

Cornhusker Economics

As part of a larger research project on the economics of beef supply chain resilience to natural disasters, financed in part by a grant from the USDA National Institute of Food and Agriculture, we obtained information from 289 processing plants across the United States about their operations during the peak COVID-19 period of March to June 2020 via a telephone survey. We collected data on plant type (slaughter, processing, both), the dominant livestock processed by the plant (predominantly beef, pork, poultry, and sheep/goat), plant capacity (maximum and typical capacity in slaughter head/day), age of establishment, and, whether the plant ceased, …

Disentangling Genotype And Environment Specific Latent Features For Improved Trait Prediction Using A Compositional Autoencoder, Anirudha Powadi, Talukder Zaki Jubery, Michael C. Tross, James C. Schnable, Baskar Ganapathysubramanian

Department of Agronomy and Horticulture: Faculty Publications

In plant breeding and genetics, predictive models traditionally rely on compact representations of high-dimensional data, often using methods like Principal Component Analysis (PCA) and, more recently, Autoencoders (AE). However, these methods do not separate genotype-specific and environment-specific features, limiting their ability to accurately predict traits influenced by both genetic and environmental factors. We hypothesize that disentangling these representations into genotype-specific and environment-specific components can enhance predictive models. To test this, we developed a compositional autoencoder (CAE) that decomposes high-dimensional data into distinct genotype-specific and environment-specific latent features. Our CAE framework employed a hierarchical architecture within an autoencoder to effectively separate …

Classics And Contemporary Popular Culture [Dialogue: The Interdisciplinary Journal Of Popular Culture And Pedagogy, Volume 1, Issue 1 (Spring 2014)], Lynnea Chapman King, Anna S. Cohenmiller

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Classics and Contemporary Popular Culture [Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy, Volume 1, Issue 1 (Spring 2014)] (Online only)

Editorial

Moving Popular Culture Studies Scholarship into the Future, Lynnea Chapman King and Anna S. CohenMiller

Guest Editorial

“καλὸν ἀνθρωπίνου βίου κάτοπτρον”: Popular Culture as a Pedagogical Lens on Greco-Roman Antiquity, Kirsten Day and Benjamin Haller

Part I: Epic Reconsiderations

Wounds that Will Not Heal: Heroism and Innocence in Shane and the Iliad, Carl A. Rubino

O Homer, Where Art Thou?: Teaching the Iliad and the Odyssey through Popular Culture, Mallory Young

The Odyssey and its Odyssey …

The Labyrinth Of Memory: Iphigeneia, Simonides, And Classical Models Of Architecture As Mind In Chris Nolan’S Inception (2010), Benjamin Haller

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Chris Nolan’s 2010 film Inception uses architecture as a language whereby to comment upon the relationship of the protagonist, Dom Cobb, with his deceased wife, Mal. This paper argues that three classical models – Homer’s tomb of Myrhine described in the Iliad, Iphigeneia’s dream of the collapse of the house of Agamemnon in Euripides’s Iphigeneia Among the Taurians, and Simonides’ Memory Palace mnemonic technique – manifest parallel uses of architecture as a metaphor for mind.

The film identifies each of its main characters – Dom, Mal, and Ariadne – with different architectures and with different modes of cognition. The …

Wounds That Will Not Heal: Heroism And Innocence In Shane And The Iliad, Carl A. Rubino

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

George Stevens’ film Shane, which dates from 1953, remains an especially successful version of the heroic paradigm that is established in Homer’s Iliad. Just as Achilles, the hero of Homer’s poem, considers abandoning the war at Troy in favor of a long and uneventful life at home, the film’s mysterious hero makes a futile attempt to abandon his violent past for a “normal life” as an ordinary farmer in the American west. In the end, however, the threatened status of the domestic world Shane is trying to enter makes it impossible for him to renounce his heroic nature and violent …

Don’T Sweat The Technique: Rhetoric, Coded Social Critique, And Conspiracy Theories In Hip-Hop, Josh Chase

Dialogue: The Interdisciplinary Journal of Popular Culture and Pedagogy

Conspiracy theories are once again a topic of heated debate in both popular and scholarly media. Critics on one side of this debate often take for granted an “underlying assumption that conspiracy theories should be subdued if not eliminated” (Uscinski 444). Other scholars have expressed concern over the ways the “conspiracy theorist” pejorative stifles dissent and regulates political rationality (Rankin; deHaven-Smith). Bratich argues that social anxieties about issues like emerging technology and race “get managed” through the public debate about conspiracy theories as an “object of concern” (160–61). This paper asks, what are the consequences when “conspiracy panic” spreads beyond …